Reference |
---|
Selvam A, Bj rnstedt M. A Novel Assay Method to Determine the β-Elimination of Se-Methylselenocysteine to Monomethylselenol by Kynurenine Aminotransferase 1. Antioxidants (Basel). 2020;9: pubmed publisher
|
Zivanović J, Kouroussis E, Kohl J, Adhikari B, Bursać B, Schott Roux S, et al. Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metab. 2019;30:1152-1170.e13 pubmed publisher
|
Zhang T, Zheng P, Shen X, Shao R, Wang B, Shen H, et al. Curcuminoid WZ26, a TrxR1 inhibitor, effectively inhibits colon cancer cell growth and enhances cisplatin-induced cell death through the induction of ROS. Free Radic Biol Med. 2019;141:93-102 pubmed publisher
|
de Souza L, Schmitz A, da Silva L, de Oliveira K, Nedel C, Tasca C, et al. Inhibition of reductase systems by 2-AAPA modulates peroxiredoxin oxidation and mitochondrial function in A172 glioblastoma cells. Toxicol In Vitro. 2017;42:273-280 pubmed publisher
|
Garcia A, Machado R, Grazul R, Lopes M, Corrêa C, Dos Santos H, et al. Novel antitumor adamantane-azole gold(I) complexes as potential inhibitors of thioredoxin reductase. J Biol Inorg Chem. 2016;21:275-92 pubmed publisher
|
Yan J, Guo Y, Wang Y, Mao F, Huang L, Li X. Design, synthesis, and biological evaluation of benzoselenazole-stilbene hybrids as multi-target-directed anti-cancer agents. Eur J Med Chem. 2015;95:220-9 pubmed publisher
|
Gallagher J, Zheng W, Rong X, Miranda N, Lin Z, Dunn B, et al. Divergence in a master variator generates distinct phenotypes and transcriptional responses. Genes Dev. 2014;28:409-21 pubmed publisher
|
Lothrop A, Snider G, Flemer S, Ruggles E, Davidson R, Lamb A, et al. Compensating for the absence of selenocysteine in high-molecular weight thioredoxin reductases: the electrophilic activation hypothesis. Biochemistry. 2014;53:664-74 pubmed publisher
|
Rovenko B, Lushchak V, Lushchak O. [Carbohydrate restriction in the larval diet causes oxidative stress in adult insects of Drosophila melanogaster]. Ukr Biokhim Zh (1999). 2013;85:61-72 pubmed
|
Lothrop A, Snider G, Ruggles E, Patel A, Lees W, Hondal R. Selenium as an electron acceptor during the catalytic mechanism of thioredoxin reductase. Biochemistry. 2014;53:654-63 pubmed publisher
|
Cao Z, Subramaniam S, Bulleid N. Lack of an efficient endoplasmic reticulum-localized recycling system protects peroxiredoxin IV from hyperoxidation. J Biol Chem. 2014;289:5490-8 pubmed publisher
|
Parker M, Zhu X, Stubbe J. Bacillus subtilis class Ib ribonucleotide reductase: high activity and dynamic subunit interactions. Biochemistry. 2014;53:766-76 pubmed publisher
|
Snider G, Dustin C, Ruggles E, Hondal R. A mechanistic investigation of the C-terminal redox motif of thioredoxin reductase from Plasmodium falciparum. Biochemistry. 2014;53:601-9 pubmed publisher
|
Lothrop A, Snider G, Ruggles E, Hondal R. Why is mammalian thioredoxin reductase 1 so dependent upon the use of selenium?. Biochemistry. 2014;53:554-65 pubmed publisher
|
Feng D, Dai Q, Xie H, Li R, Zheng G, Wang J, et al. [Protective effect of Pinus massoniana bark extracts against cisplatin-induced nephrotoxicity in human embryonic kidney cells]. Zhongguo Zhong Yao Za Zhi. 2013;38:2868-73 pubmed
|
Luo Z, Sheng J, Sun Y, Lu C, Yan J, Liu A, et al. Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen. J Med Chem. 2013;56:9089-99 pubmed publisher
|
Peng X, Zhang M, Conserva F, Hosny G, Selivanova G, Bykov V, et al. APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase. Cell Death Dis. 2013;4:e881 pubmed publisher
|
Randall M, Hristova M, van Der Vliet A. Protein alkylation by the α,β-unsaturated aldehyde acrolein. A reversible mechanism of electrophile signaling?. FEBS Lett. 2013;587:3808-14 pubmed publisher
|
Jayakumar S, Kunwar A, Sandur S, Pandey B, Chaubey R. Differential response of DU145 and PC3 prostate cancer cells to ionizing radiation: role of reactive oxygen species, GSH and Nrf2 in radiosensitivity. Biochim Biophys Acta. 2014;1840:485-94 pubmed publisher
|
Joshi R, Kumar A, Manral S, Sinha R, Arora S, Sharma A, et al. Calreticulin transacetylase mediated upregulation of thioredoxin by 7,8-diacetoxy-4-methylcoumarin enhances the antioxidant potential and the expression of vascular endothelial growth factor in peripheral blood mononuclear cells. Chem Biol Interact. 2013;206:327-36 pubmed publisher
|
Kim S, Kim D, Jung W, Koo J. The expression of redox proteins in phyllodes tumor. Breast Cancer Res Treat. 2013;141:365-74 pubmed publisher
|
Casagrande N, De Paoli M, Celegato M, Borghese C, Mongiat M, Colombatti A, et al. Preclinical evaluation of a new liposomal formulation of cisplatin, lipoplatin, to treat cisplatin-resistant cervical cancer. Gynecol Oncol. 2013;131:744-52 pubmed publisher
|
Xu J, Croitoru V, Rutishauser D, Cheng Q, Arner E. Wobble decoding by the Escherichia coli selenocysteine insertion machinery. Nucleic Acids Res. 2013;41:9800-11 pubmed publisher
|
Cunniff B, Snider G, Fredette N, Hondal R, Heintz N. A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates. Anal Biochem. 2013;443:34-40 pubmed publisher
|
Zhu Z, Yang G, Wang Y, Yang J, Gao A, Niu P, et al. Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in rats. Toxicol Lett. 2013;222:289-94 pubmed publisher
|
Marco S, Rullo R, Albino A, Masullo M, De Vendittis E, Amato M. The thioredoxin system in the dental caries pathogen Streptococcus mutans and the food-industry bacterium Streptococcus thermophilus. Biochimie. 2013;95:2145-56 pubmed publisher
|
Bitar M, Abdel Halim S, Al Mulla F. Caveolin-1/PTRF upregulation constitutes a mechanism for mediating p53-induced cellular senescence: implications for evidence-based therapy of delayed wound healing in diabetes. Am J Physiol Endocrinol Metab. 2013;305:E951-63 pubmed publisher
|
Lepistö A, Pakula E, Toivola J, Krieger Liszkay A, Vignols F, Rintamäki E. Deletion of chloroplast NADPH-dependent thioredoxin reductase results in inability to regulate starch synthesis and causes stunted growth under short-day photoperiods. J Exp Bot. 2013;64:3843-54 pubmed publisher
|
Stangherlin A, Reddy A. Regulation of circadian clocks by redox homeostasis. J Biol Chem. 2013;288:26505-11 pubmed publisher
|
Fritz Wolf K, Jortzik E, Stumpf M, Preuss J, Iozef R, Rahlfs S, et al. Crystal structure of the Plasmodium falciparum thioredoxin reductase-thioredoxin complex. J Mol Biol. 2013;425:3446-60 pubmed publisher
|
Dai B, Yoo S, Bartholomeusz G, Graham R, Majidi M, Yan S, et al. KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancer. Cancer Res. 2013;73:5532-43 pubmed publisher
|
Engelman R, Weisman Shomer P, Ziv T, Xu J, Arner E, Benhar M. Multilevel regulation of 2-Cys peroxiredoxin reaction cycle by S-nitrosylation. J Biol Chem. 2013;288:11312-24 pubmed publisher
|
Cebula M, Moolla N, Capovilla A, Arner E. The rare TXNRD1_v3 ("v3") splice variant of human thioredoxin reductase 1 protein is targeted to membrane rafts by N-acylation and induces filopodia independently of its redox active site integrity. J Biol Chem. 2013;288:10002-11 pubmed publisher
|
Schlosser S, Leitsch D, Duch ne M. Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example. Biochem J. 2013;451:277-88 pubmed publisher
|
Van Laer K, Dziewulska A, Fislage M, Wahni K, Hbeddou A, Collet J, et al. NrdH-redoxin of Mycobacterium tuberculosis and Corynebacterium glutamicum dimerizes at high protein concentration and exclusively receives electrons from thioredoxin reductase. J Biol Chem. 2013;288:7942-55 pubmed publisher
|
Rovenko B, Lushchak O, Lozins kyĭ O, Kubrak O, Lushchak V. [Mild oxidative stress in fruit fly Drosophila melanogaster caused by products of sucrose hydrolysis]. Ukr Biokhim Zh (1999). 2012;84:97-105 pubmed
|
Liu C, Liu Z, Li M, Li X, Wong Y, Ngai S, et al. Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase. PLoS ONE. 2013;8:e53945 pubmed publisher
|
Cohen Kutner M, Khomsky L, Trus M, Aisner Y, Niv M, Benhar M, et al. Thioredoxin-mimetic peptides (TXM) reverse auranofin induced apoptosis and restore insulin secretion in insulinoma cells. Biochem Pharmacol. 2013;85:977-90 pubmed publisher
|
Navakoski de Oliveira K, Andermark V, von Grafenstein S, Onambele L, Dahl G, Rubbiani R, et al. Butyltin(IV) benzoates: inhibition of thioredoxin reductase, tumor cell growth inhibition, and interactions with proteins. ChemMedChem. 2013;8:256-64 pubmed publisher
|
Fujishiro S, Dodo K, Iwasa E, Teng Y, Sohtome Y, Hamashima Y, et al. Epidithiodiketopiperazine as a pharmacophore for protein lysine methyltransferase G9a inhibitors: reducing cytotoxicity by structural simplification. Bioorg Med Chem Lett. 2013;23:733-6 pubmed publisher
|
Lu J, Vlamis Gardikas A, Kandasamy K, Zhao R, Gustafsson T, Engstrand L, et al. Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione. FASEB J. 2013;27:1394-403 pubmed publisher
|
Eweas A, Allam G, Abuelsaad A, Alghamdi A, Maghrabi I. Design, synthesis, anti-schistosomal activity and molecular docking of novel 8-hydroxyquinoline-5-sufonyl 1,4-diazepine derivatives. Bioorg Chem. 2013;46:17-25 pubmed publisher
|
Fernandes A, Wallenberg M, Gandin V, Misra S, Tisato F, Marzano C, et al. Methylselenol formed by spontaneous methylation of selenide is a superior selenium substrate to the thioredoxin and glutaredoxin systems. PLoS ONE. 2012;7:e50727 pubmed publisher
|
Lopert P, Day B, Patel M. Thioredoxin reductase deficiency potentiates oxidative stress, mitochondrial dysfunction and cell death in dopaminergic cells. PLoS ONE. 2012;7:e50683 pubmed publisher
|
Wang P, Wu Y, Li X, Ma X, Zhong L. Thioredoxin and thioredoxin reductase control tissue factor activity by thiol redox-dependent mechanism. J Biol Chem. 2013;288:3346-58 pubmed publisher
|
Pirazzini M, Bordin F, Rossetto O, Shone C, Binz T, Montecucco C. The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals. FEBS Lett. 2013;587:150-5 pubmed publisher
|
Ekström L, Johansson M, Monostory K, Rundlöf A, Arner E, Björkhem Bergman L. Simvastatin inhibits the core promoter of the TXNRD1 gene and lowers cellular TrxR activity in HepG2 cells. Biochem Biophys Res Commun. 2013;430:90-4 pubmed publisher
|
Oehninger L, Stefanopoulou M, Alborzinia H, Schur J, Ludewig S, Namikawa K, et al. Evaluation of arene ruthenium(II) N-heterocyclic carbene complexes as organometallics interacting with thiol and selenol containing biomolecules. Dalton Trans. 2013;42:1657-66 pubmed publisher
|
Ibáñez E, Stoedter M, Hofmann P, Plano D, Calvo A, Nguewa P, et al. Structure- and cell-specific effects of imidoselenocarbamates on selenoprotein expression and activity in liver cells in culture. Metallomics. 2012;4:1297-307 pubmed publisher
|
Debnath A, Ndao M, Reed S. Reprofiled drug targets ancient protozoans: drug discovery for parasitic diarrheal diseases. Gut Microbes. 2013;4:66-71 pubmed publisher
|
Méplan C, Rohrmann S, Steinbrecher A, Schomburg L, Jansen E, Linseisen J, et al. Polymorphisms in thioredoxin reductase and selenoprotein K genes and selenium status modulate risk of prostate cancer. PLoS ONE. 2012;7:e48709 pubmed publisher
|
Sobhakumari A, Love Homan L, Fletcher E, Martin S, Parsons A, Spitz D, et al. Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism. PLoS ONE. 2012;7:e48175 pubmed publisher
|
Ghosh P, Roy S, Chakraborty P, Ghosh S, Bhattacharya S. Effects of organoselenium compound 2-(5-selenocyanato-pentyl)-benzo[de]isoquinoline 1,3-dione on cisplatin induced nephrotoxicity and genotoxicity: an investigation of the influence of the compound on oxidative stress and antioxidant enzyme system. Biometals. 2013;26:61-73 pubmed publisher
|
Bohrer A, Massot V, Innocenti G, Reichheld J, Issakidis Bourguet E, Vanacker H. New insights into the reduction systems of plastidial thioredoxins point out the unique properties of thioredoxin z from Arabidopsis. J Exp Bot. 2012;63:6315-23 pubmed publisher
|
Watson M, van Leer L, Vanderlelie J, Perkins A. Selenium supplementation protects trophoblast cells from oxidative stress. Placenta. 2012;33:1012-9 pubmed publisher
|
Lee Y, Kim S, Lazar P, Moon J, Hwang S, Thangapandian S, et al. Comparative molecular modeling study of Arabidopsis NADPH-dependent thioredoxin reductase and its hybrid protein. PLoS ONE. 2012;7:e46279 pubmed publisher
|
Jin X, Stamnaes J, Klöck C, Diraimondo T, Sollid L, Khosla C. Activation of extracellular transglutaminase 2 by thioredoxin. J Biol Chem. 2011;286:37866-73 pubmed publisher
|
May J, Qu Z, Nelson D. Uptake and reduction of alpha-lipoic acid by human erythrocytes. Clin Biochem. 2007;40:1135-42 pubmed
|
Nordman T, Xia L, Björkhem Bergman L, Damdimopoulos A, Nalvarte I, Arner E, et al. Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase. Biofactors. 2003;18:45-50 pubmed
|
Moore E, Reichard P, Thelander L. ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES.V. PURIFICATION AND PROPERTIES OF THIOREDOXIN REDUCTASE FROM ESCHERICHIA COLI B. J Biol Chem. 1964;239:3445-52 pubmed
|
Arner E, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem. 2000;267:6102-9 pubmed
|
Zhong L, Holmgren A. Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations. J Biol Chem. 2000;275:18121-8 pubmed
|
Speranza M, Ronchi S, Minchiotti L. Purification and characterization of yeast thioredoxin reductase. Biochim Biophys Acta. 1973;327:274-81 pubmed
|