This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Thrombin human
catalog :
T9326
citations: 71
Reference
Cennamo N, Pasquardini L, Arcadio F, Vanzetti L, Bossi A, Zeni L. D-shaped plastic optical fibre aptasensor for fast thrombin detection in nanomolar range. Sci Rep. 2019;9:18740 pubmed publisher
Hong L, Du X, You T, Sun L, Li W, Xiao L, et al. Reciprocal enhancement of thrombosis by endothelial-to-mesenchymal transition induced by iliac vein compression. Life Sci. 2019;233:116659 pubmed publisher
Piao C, Ralay Ranaivo H, Rusie A, Wadhwani N, Koh S, Wainwright M. Thrombin decreases expression of the glutamate transporter GLAST and inhibits glutamate uptake in primary cortical astrocytes via the Rho kinase pathway. Exp Neurol. 2015;273:288-300 pubmed publisher
Hansson K, Gustafsson D, Skärby T, Frison L, Berntorp E. Effects of recombinant human prothrombin on thrombin generation in plasma from patients with hemophilia A and B. J Thromb Haemost. 2015;13:1293-300 pubmed publisher
Stroka D, Keogh A, Vu D, Fort A, Stoffel M, Kühni Boghenbor K, et al. In vitro rescue of FGA deletion by lentiviral transduction of an afibrinogenemic patient's hepatocytes. J Thromb Haemost. 2014;12:1874-9 pubmed publisher
Ataollahi F, Pingguan Murphy B, Moradi A, Wan Abas W, Chua K, Abu Osman N. New method for the isolation of endothelial cells from large vessels. Cytotherapy. 2014;16:1145-52 pubmed publisher
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Davalos D, Baeten K, Whitney M, Mullins E, Friedman B, Olson E, et al. Early detection of thrombin activity in neuroinflammatory disease. Ann Neurol. 2014;75:303-8 pubmed publisher
Fiore A, Grandmougin D, Maureira J, Elfarra M, Laurent N, Andronache M, et al. Efficacy of TachoSil® as a sutureless hemostatic patch to repair a perforation of the interventricular groove during endocardial radiofrequency ablation. J Cardiovasc Surg (Torino). 2014;55:295-8 pubmed
Hoth J, Wells J, Jones S, Yoza B, McCall C. Complement mediates a primed inflammatory response after traumatic lung injury. J Trauma Acute Care Surg. 2014;76:601-8; discussion 608-9 pubmed publisher
Viennet C, Laurensou C, Goydadin A, Faivre B, Muret P, Humbert P. Development of an in vitro fibrin clot model to evaluate fibrinolytic agents for wound care application. J Wound Care. 2014;23:66-7, 70, 72 pubmed
van den Biggelaar M, Hernández Fernaud J, van den Eshof B, Neilson L, Meijer A, Mertens K, et al. Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells. Blood. 2014;123:e22-36 pubmed publisher
Carcaillon L, Brailly Tabard S, Ancelin M, Rouaud O, Dartigues J, Guiochon Mantel A, et al. High plasma estradiol interacts with diabetes on risk of dementia in older postmenopausal women. Neurology. 2014;82:504-11 pubmed publisher
Lyden P, Pereira B, Chen B, Zhao L, Lamb J, Lei I, et al. Direct thrombin inhibitor argatroban reduces stroke damage in 2 different models. Stroke. 2014;45:896-9 pubmed publisher
Gadwal S, Korotkov K, Delarosa J, Hol W, Sandkvist M. Functional and structural characterization of Vibrio cholerae extracellular serine protease B, VesB. J Biol Chem. 2014;289:8288-98 pubmed publisher
Beaulieu L, Lin E, Mick E, Koupenova M, Weinberg E, Kramer C, et al. Interleukin 1 receptor 1 and interleukin 1? regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans. Arterioscler Thromb Vasc Biol. 2014;34:552-64 pubmed publisher
Colucci G, Stutz M, Rochat S, Conte T, Pavicic M, Reusser M, et al. The effect of desmopressin on platelet function: a selective enhancement of procoagulant COAT platelets in patients with primary platelet function defects. Blood. 2014;123:1905-16 pubmed publisher
Elmahdy M, Kassem H, Ewis E, Mahdy S. Comparison between ultrasound-guided compression and para-aneurysmal saline injection in the treatment of postcatheterization femoral artery pseudoaneurysms. Am J Cardiol. 2014;113:871-6 pubmed publisher
Hamaji M, Kojima F, Nakamura T. Collagen fleece failed to prevent intrapleural adhesions in a canine model: failure of murine models to translate into a large animal model. Gen Thorac Cardiovasc Surg. 2014;62:202-3 pubmed publisher
Rocanin Arjo A, Cohen W, Carcaillon L, Frere C, Saut N, Letenneur L, et al. A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential. Blood. 2014;123:777-85 pubmed publisher
Tian X, Tian Y, Gawlak G, Sarich N, Wu T, Birukova A. Control of vascular permeability by atrial natriuretic peptide via a GEF-H1-dependent mechanism. J Biol Chem. 2014;289:5168-83 pubmed publisher
Lin P, Chen X, Moktan H, Arrese E, Duan L, Wang L, et al. Membrane attachment and structure models of lipid storage droplet protein 1. Biochim Biophys Acta. 2014;1838:874-81 pubmed publisher
Zentai C, Braunschweig T, Rossaint R, Daniels M, Czaplik M, Tolba R, et al. Fibrin patch in a pig model with blunt liver injury under severe hypothermia. J Surg Res. 2014;187:616-24 pubmed publisher
Gao F, Liu F, Chen Z, Hua Y, Keep R, Xi G. Hydrocephalus after intraventricular hemorrhage: the role of thrombin. J Cereb Blood Flow Metab. 2014;34:489-94 pubmed publisher
Miyoshi Y, Sogabe O, Tanaka S. [Ultrasound-guided percutaneous thrombin injection therapy for the treatment of iatrogenic brachial pseudoaneurysms]. Kyobu Geka. 2013;66:1045-9 pubmed
Zecher D, Cumpelik A, Schifferli J. Erythrocyte-derived microvesicles amplify systemic inflammation by thrombin-dependent activation of complement. Arterioscler Thromb Vasc Biol. 2014;34:313-20 pubmed publisher
Bastiaans J, van Meurs J, van Holten Neelen C, Nagtzaam N, van Hagen P, Chambers R, et al. Thrombin induces epithelial-mesenchymal transition and collagen production by retinal pigment epithelial cells via autocrine PDGF-receptor signaling. Invest Ophthalmol Vis Sci. 2013;54:8306-14 pubmed publisher
Tisi P, Callam M. Treatment for femoral pseudoaneurysms. Cochrane Database Syst Rev. 2013;:CD004981 pubmed publisher
Walker B, Towhid S, Schmid E, Hoffmann S, Abed M, Münzer P, et al. Dynamic adhesion of eryptotic erythrocytes to immobilized platelets via platelet phosphatidylserine receptors. Am J Physiol Cell Physiol. 2014;306:C291-7 pubmed publisher
Lopes P, Lao E, Nie S, Ma C. Failed thrombin treatment due to patent collateral leakage after refractory guidewire-induced coronary artery perforation. Acta Cardiol. 2013;68:525-7 pubmed
Bauer K. Dabigatran, ROCKET atrial fibrillation, and beyond: basic science, mechanisms of agents, monitoring, and reversal. Stroke. 2013;44:S38-40 pubmed publisher
Tang T, Zhou H. Response. J Neurosurg. 2013;118:914-5 pubmed
Xu F, Hua M, Luo L, Du H, Yang Y. Electrochemical aptamer sensor for thrombin detection based on Au nanoneedle and enzymatic ascorbic acid oxidization. J Nanosci Nanotechnol. 2013;13:558-63 pubmed
Chang C, Chen Y, Kao Y, Lin Y, Chen S, Chen Y. Response to letter regarding article, "Dabigatran and thrombin modulate electrophysiological characteristics of pulmonary vein and left atrium" by Chang et al. Circ Arrhythm Electrophysiol. 2013;6:e23 pubmed publisher
Lin G, Li Y, Han C. Letter by Lin et al regarding article, "Dabigatran and thrombin modulate electrophysiological characteristics of pulmonary vein and left atrium" by Chang et al. Circ Arrhythm Electrophysiol. 2013;6:e22 pubmed publisher
Geoghegan J, Monk I, O Gara J, Foster T. Subdomains N2N3 of fibronectin binding protein A mediate Staphylococcus aureus biofilm formation and adherence to fibrinogen using distinct mechanisms. J Bacteriol. 2013;195:2675-83 pubmed publisher
King C, Holley A, Moores L. Moving toward a more ideal anticoagulant: the oral direct thrombin and factor Xa inhibitors. Chest. 2013;143:1106-1116 pubmed publisher
Vidaeff A, Monga M, Ramin S, Saade G, Sangi Haghpeykar H. Is thrombin activation predictive of subsequent preterm delivery?. Am J Obstet Gynecol. 2013;208:306.e1-7 pubmed publisher
Khan M, Maasch C, Vater A, Klussmann S, Morser J, Leung L, et al. Targeting complement component 5a promotes vascular integrity and limits airway remodeling. Proc Natl Acad Sci U S A. 2013;110:6061-6 pubmed publisher
Clark S, Thomas C, Hammond V, Aldrovandi M, Wilkinson G, Hart K, et al. Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation. Proc Natl Acad Sci U S A. 2013;110:5875-80 pubmed publisher
Mattheij N, Gilio K, van Kruchten R, Jobe S, Wieschhaus A, Chishti A, et al. Dual mechanism of integrin ?IIb?3 closure in procoagulant platelets. J Biol Chem. 2013;288:13325-36 pubmed publisher
Kovach I, Kakalis L, Jordan F, Zhang D. Proton bridging in the interactions of thrombin with hirudin and its mimics. Biochemistry. 2013;52:2472-81 pubmed publisher
Kowey P, Naccarelli G. The reply. Am J Med. 2013;126:e23 pubmed publisher
Pazmiño P. Dabigatran: a nephrological way out. Am J Med. 2013;126:e21 pubmed publisher
Bonaca M, Scirica B, Creager M, Olin J, Bounameaux H, Dellborg M, et al. Vorapaxar in patients with peripheral artery disease: results from TRA2{degrees}P-TIMI 50. Circulation. 2013;127:1522-9, 1529e1-6 pubmed publisher
Shiraishi M, Tamura K, Egoshi M, Miyamoto A. Cholesterol enrichment of rabbit platelets enhances the Ca(2+) entry pathway induced by platelet-derived secondary feedback agonists. Life Sci. 2013;92:838-44 pubmed publisher
Garber S, Sivakumar W, Schmidt R. Response. J Neurosurg. 2013;118:485 pubmed
Garber S, Sivakumar W, Schmidt R. Response. J Neurosurg. 2013;118:483 pubmed
Kohler H. Interaction between FXIII and fibrinogen. Blood. 2013;121:1931-2 pubmed publisher
Lin H, Trejo J. Transactivation of the PAR1-PAR2 heterodimer by thrombin elicits ?-arrestin-mediated endosomal signaling. J Biol Chem. 2013;288:11203-15 pubmed publisher
Lin K, Kuo J, Lu W, Chung C, Chou D, Huang S, et al. Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo. Biochem Pharmacol. 2013;85:1478-85 pubmed publisher
Wong P, White A, Luettgen J. Inhibitory effect of apixaban compared with rivaroxaban and dabigatran on thrombin generation assay. Hosp Pract (1995). 2013;41:19-25 pubmed publisher
Chen X, Zhang Y, Wang Y, Li D, Zhang L, Wang K, et al. PDK1 regulates platelet activation and arterial thrombosis. Blood. 2013;121:3718-26 pubmed publisher
Cheranova D, Gibson M, Chaudhary S, Zhang L, Heruth D, Grigoryev D, et al. RNA-seq analysis of transcriptomes in thrombin-treated and control human pulmonary microvascular endothelial cells. J Vis Exp. 2013;: pubmed publisher
Klompenhouwer E, Thomassen I, Teijink J. [A man with a bump on his forehead after a fall]. Ned Tijdschr Geneeskd. 2013;157:A4231 pubmed
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Metzger U, Schall C, Zocher G, Uns ld I, Stec E, Li S, et al. The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria. Proc Natl Acad Sci U S A. 2009;106:14309-14 pubmed publisher
Mieczkowski C, Iavarone A, Alber T. Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase. EMBO J. 2008;27:3186-97 pubmed publisher
Agarwal S, Simonds W, Marx S. The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3. Mol Cancer. 2008;7:65 pubmed publisher
Bacha U, Barrila J, Gabelli S, Kiso Y, Mario Amzel L, Freire E. Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CL(pro). Chem Biol Drug Des. 2008;72:34-49 pubmed publisher
Nickson A, Stoll K, Clarke J. Folding of a LysM domain: entropy-enthalpy compensation in the transition state of an ideal two-state folder. J Mol Biol. 2008;380:557-69 pubmed publisher
Carter J, Buerke U, Rossner E, Russ M, Schubert S, Schmidt H, et al. Anti-inflammatory actions of aprotinin provide dose-dependent cardioprotection from reperfusion injury. Br J Pharmacol. 2008;155:93-102 pubmed publisher
Kaushik S, Cuervo A. Chaperone-mediated autophagy. Methods Mol Biol. 2008;445:227-44 pubmed publisher
Brailoiu E, Jiang X, Brailoiu G, Yang J, Chang J, Wang H, et al. State-dependent calcium mobilization by urotensin-II in cultured human endothelial cells. Peptides. 2008;29:721-6 pubmed publisher
Wheeler Jones C, Learmonth M, Martin H, Aitken A. Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation. Biochem J. 1996;315 ( Pt 1):41-7 pubmed
Cho K, Tanaka T, Cook R, Kisiel W, Fujikawa K, Kurachi K, et al. Active-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide and thio ester substrates. Biochemistry. 1984;23:644-50 pubmed
MacGillivray R, Davie E. Characterization of bovine prothrombin mRNA and its translation product. Biochemistry. 1984;23:1626-34 pubmed
Lundblad R, Kingdon H, Mann K. Thrombin. Methods Enzymol. 1976;45:156-76 pubmed
Mann K. Prothrombin. Methods Enzymol. 1976;45:123-56 pubmed
product information
Catalog Number :
T9326
Product Name :
Thrombin human
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
BioUltra, recombinant, expressed in HEK 293 cells, aqueous solution, ≥95% (SDS-PAGE)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA