Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; 1:10,000; loading ...; fig 2b
| Ikari S, Yang Q, Lu S, Liu Y, Hao F, Tong G, et al. Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations. Antioxidants (Basel). 2021;10: pubmed publisher
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- immunocytochemistry; human; 1:200; loading ...; fig 4g
- western blot; human; 1:5000; loading ...; fig 1d, 1g
| Wang L, Rajah A, Brown C, McCaffrey L. CD13 orients the apical-basal polarity axis necessary for lumen formation. Nat Commun. 2021;12:4697 pubmed publisher
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- immunocytochemistry; human; 1:250; loading ...; fig 5a
| Watson A, Grant A, Parker S, Hill S, Whalen M, Chakrabarti J, et al. Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning. Cell Rep. 2021;35:109293 pubmed publisher
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- western blot; mouse; loading ...; fig 8b
| Ramos Morales E, Bayam E, Del Pozo Rodríguez J, Salinas Giegé T, Marek M, Tilly P, et al. The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination. Nucleic Acids Res. 2021;49:6529-6548 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 2a
| Kildey K, Gandhi N, Sahin K, Shah E, Boittier E, Duijf P, et al. Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy. Commun Biol. 2021;4:638 pubmed publisher
|
- western blot; human; loading ...; fig 1b
| Nakajima W, Miyazaki K, Asano Y, Kubota S, Tanaka N. Krüppel-Like Factor 4 and Its Activator APTO-253 Induce NOXA-Mediated, p53-Independent Apoptosis in Triple-Negative Breast Cancer Cells. Genes (Basel). 2021;12: pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig 2h
| Kariya Y, Oyama M, Suzuki T, Kariya Y. αvβ3 Integrin induces partial EMT independent of TGF-β signaling. Commun Biol. 2021;4:490 pubmed publisher
|
- western blot; human; 1:2000; fig s5a
| Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed publisher
|
- western blot; human; fig 2c, 2d
| Li T, Huang T, Du M, Chen X, Du F, Ren J, et al. Phosphorylation and chromatin tethering prevent cGAS activation during mitosis. Science. 2021;371: pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig 1s2a
| Vergarajauregui S, Becker R, Steffen U, Sharkova M, Esser T, Petzold J, et al. AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9. elife. 2020;9: pubmed publisher
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- western blot; mouse; 1:4000; loading ...; fig 2a
| Fomicheva M, Macara I. Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation. elife. 2020;9: pubmed publisher
|
- western blot; mouse; loading ...; fig 1d
| Yan J, Bengtson C, Buchthal B, Hagenston A, Bading H. Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants. Science. 2020;370: pubmed publisher
|
- western blot; human; 1:2000; loading ...; fig 5s3a
| Rogerson C, Ogden S, Britton E, Ang Y, Sharrocks A. Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma. elife. 2020;9: pubmed publisher
|
- western blot; human; loading ...; fig 5d
| Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 4a
| Berges R, Tchoghandjian A, Serge A, Honore S, Figarella Branger D, Bachmann F, et al. EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis. Oncotarget. 2020;11:759-774 pubmed publisher
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- western blot; mouse; 1:8000; loading ...; fig s7a
| Nagaoka S, Nakaki F, Miyauchi H, Nosaka Y, Ohta H, Yabuta Y, et al. ZGLP1 is a determinant for the oogenic fate in mice. Science. 2020;: pubmed publisher
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- immunocytochemistry; human; loading ...; fig 6b
| Bodrug T, Wilson Kubalek E, Nithianantham S, Thompson A, Alfieri A, Gaska I, et al. The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. elife. 2020;9: pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig s3a
| Lehmann M, Lukonin I, Noe F, Schmoranzer J, Clementi C, Loerke D, et al. Nanoscale coupling of endocytic pit growth and stability. Sci Adv. 2019;5:eaax5775 pubmed publisher
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- western blot; human; loading ...; fig s1c
| Larson G, Tran V, Yu S, Cai Y, Higgins C, Smith D, et al. EPS8 Facilitates Uncoating of Influenza A Virus. Cell Rep. 2019;29:2175-2183.e4 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 7a
- western blot; mouse; 1:2000; loading ...; fig 6a
| Vohnoutka R, Gulvady A, Goreczny G, Alpha K, Handelman S, Sexton J, et al. The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts. Mol Biol Cell. 2019;30:3037-3056 pubmed publisher
|
- western blot; mouse; 1:10,000; loading ...; fig s7g
| Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig 4c
| Morishita H, Zhao Y, Tamura N, Nishimura T, Kanda Y, Sakamaki Y, et al. A critical role of VMP1 in lipoprotein secretion. elife. 2019;8: pubmed publisher
|
- western blot; human; loading ...; fig 2d
| Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed publisher
|
- immunocytochemistry; human; loading ...; fig 2c
| Wang R, Yu R, Zhu C, Lin H, Lu X, Wang H. Tubulin detyrosination promotes human trophoblast syncytium formation. J Mol Cell Biol. 2019;: pubmed publisher
|
- immunocytochemistry; human; loading ...; fig 1b
| Hartono -, Hazawa M, Lim K, Dewi F, Kobayashi A, Wong R. Nucleoporin Nup58 localizes to centrosomes and mid-bodies during mitosis. Cell Div. 2019;14:7 pubmed publisher
|
- western blot; human; loading ...; fig 6a
| Dorsch L, Schuldt M, dos Remedios C, Schinkel A, de Jong P, Michels M, et al. Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy. Cells. 2019;8: pubmed publisher
|
- western blot; human; loading ...; fig s6b
| Marcus J, Bejerano Sagie M, Patterson N, Bagchi S, Verkhusha V, Connolly D, et al. Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions. Oncogene. 2019;38:5839-5859 pubmed publisher
|
- western blot; human; 1:5000; loading ...; fig 3d
| Sajini A, Choudhury N, Wagner R, Bornelöv S, Selmi T, Spanos C, et al. Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation. Nat Commun. 2019;10:2550 pubmed publisher
|
- western blot; human; 1:5000; loading ...; fig s1f
| Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig s5g
| A M, Fung T, Kettenbach A, Chakrabarti R, Higgs H. A complex containing lysine-acetylated actin inhibits the formin INF2. Nat Cell Biol. 2019;21:592-602 pubmed publisher
|
- western blot; mouse; 1:10,000; loading ...; fig s1
| Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed publisher
|
- western blot; human; loading ...; fig 3h
| Tsai C, Tsai C, Yi J, Kao H, Huang Y, Wang C, et al. Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells. Sci Rep. 2019;9:5197 pubmed publisher
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- western blot; human; fig 1c
| Patel N, Wang J, Shiozawa K, Jones K, Zhang Y, Prokop J, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. iScience. 2019;13:43-54 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 1c
| Smith B, Wang S, Jaime Figueroa S, Harbin A, Wang J, Hamman B, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019;10:131 pubmed publisher
|
- western blot; mouse; 1:2000; loading ...; fig 1a
| Weinberg S, Singer B, Steinert E, Martinez C, Mehta M, Martínez Reyes I, et al. Mitochondrial complex III is essential for suppressive function of regulatory T cells. Nature. 2019;565:495-499 pubmed publisher
|
- western blot; human; loading ...; fig 1a
| Cui Y, Carosi J, Yang Z, Ariotti N, Kerr M, Parton R, et al. Retromer has a selective function in cargo sorting via endosome transport carriers. J Cell Biol. 2019;218:615-631 pubmed publisher
|
- western blot; human; 1:5000; loading ...; fig 5b
| Makhoul C, Gosavi P, Duffield R, Delbridge B, Williamson N, Gleeson P. Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Mol Biol Cell. 2019;30:370-386 pubmed publisher
|
- western blot; human; 1:1000; loading ...; fig s1a
| Arii J, Watanabe M, Maeda F, Tokai Nishizumi N, Chihara T, Miura M, et al. ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity. Nat Commun. 2018;9:3379 pubmed publisher
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- western blot; human; loading ...; fig 1h
| Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, et al. VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science. 2018;361:290-295 pubmed publisher
|
- immunohistochemistry; zebrafish ; 1:500; fig 4d
| Song P, Perkins B. Developmental expression of the zebrafish Arf-like small GTPase paralogs arl13a and arl13b. Gene Expr Patterns. 2018;29:82-87 pubmed publisher
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- western blot; mouse; loading ...
| Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed publisher
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- western blot; human; loading ...; fig 1d
| Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al. SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science. 2018;360:800-805 pubmed publisher
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- western blot; mouse; loading ...; fig 3d
| Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed publisher
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- immunocytochemistry; human; 1:500; loading ...; fig 2c
| Ruppert J, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash A, et al. HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry. EMBO J. 2018;37: pubmed publisher
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- western blot; human; 1:50,000; loading ...; fig s2f
| Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed publisher
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- immunocytochemistry; mouse; 1:100; loading ...; fig 3a
| Qu X, Yuan F, Corona C, Pasini S, Pero M, Gundersen G, et al. Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity. J Cell Biol. 2017;216:3161-3178 pubmed publisher
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- immunocytochemistry; human; 1:100; loading ...; fig 6a
| Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, et al. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Sci Rep. 2017;7:1474 pubmed publisher
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- immunocytochemistry; human; loading ...; fig s2d
| Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig s4f
| Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard Levin Z, et al. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev. 2017;31:463-480 pubmed publisher
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- western blot; human; 1:2000; loading ...; fig s5c
| Bohnacker T, Prota A, Beaufils F, Burke J, Melone A, Inglis A, et al. Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun. 2017;8:14683 pubmed publisher
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- immunocytochemistry; mouse; 1:1000; loading ...; fig s16a
| Martínez Martín N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, et al. A switch from canonical to noncanonical autophagy shapes B cell responses. Science. 2017;355:641-647 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 7a
- western blot; human; loading ...; fig 3b
| Francis J, Newman L, Cunningham L, Kahn R. A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network. J Biol Chem. 2017;292:4336-4349 pubmed publisher
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- immunocytochemistry; Japanese rice fish; 1:100; loading ...; fig s10a
| Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, et al. Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses. Nat Commun. 2017;8:14090 pubmed publisher
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- immunocytochemistry; human; loading ...; fig s2i
| Bendre S, Rondelet A, Hall C, Schmidt N, Lin Y, Brouhard G, et al. GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK. J Cell Biol. 2016;215:631-647 pubmed
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- immunocytochemistry; fruit fly ; 1:1000; loading ...; fig 3a
| Qu Y, Hahn I, Webb S, Pearce S, Prokop A. Periodic actin structures in neuronal axons are required to maintain microtubules. Mol Biol Cell. 2017;28:296-308 pubmed publisher
|
- immunocytochemistry; human; loading ...; fig 2a
| Capalbo L, Mela I, Abad M, Jeyaprakash A, Edwardson J, D Avino P. Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis. Open Biol. 2016;6: pubmed
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- western blot; human; fig 3
- western blot; mouse; fig 6
| Nowacka J, Baumgartner C, Pelorosso C, Roth M, Zuber J, Baccarini M. MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 2016;7:80113-80130 pubmed publisher
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- western blot; human; fig 1
| Andriani G, Almeida V, Faggioli F, Mauro M, Tsai W, Santambrogio L, et al. Whole Chromosome Instability induces senescence and promotes SASP. Sci Rep. 2016;6:35218 pubmed publisher
|
- immunocytochemistry; mouse; 1:1000; loading ...; fig 2c
| Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
|
- western blot; human; loading ...; fig 5b
| Koch K, Hartmann R, Schröter F, Suwala A, Maciaczyk D, Krüger A, et al. Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells. Oncotarget. 2016;7:73414-73431 pubmed publisher
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- immunocytochemistry; human; 1:500
| Truong D, Puleo J, Llave A, Mouneimne G, Kamm R, Nikkhah M. Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment. Sci Rep. 2016;6:34094 pubmed publisher
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- proximity ligation assay; mouse; 1:20; fig 4
| Frolikova M, Sebkova N, Ded L, Dvorakova Hortova K. Characterization of CD46 and ?1 integrin dynamics during sperm acrosome reaction. Sci Rep. 2016;6:33714 pubmed publisher
|
- western blot; mouse; fig 1
| Kotoku T, Kosaka K, Nishio M, Ishida Y, Kawaichi M, Matsuda E. CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells. Sci Rep. 2016;6:34188 pubmed publisher
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- western blot; human; 1:10,000; fig s8
| Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed publisher
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- western blot; human; fig 3
| Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
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- western blot; human; 1:1000; fig 2c
| Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed publisher
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- immunocytochemistry; fruit fly ; 1:2000; fig 5
- western blot; fruit fly ; 1:5000; fig 4
| Meghini F, Martins T, Tait X, Fujimitsu K, Yamano H, Glover D, et al. Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. Nat Commun. 2016;7:12607 pubmed publisher
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- western blot; human; 1:2500; fig 4
- western blot; rat; 1:2500; fig s2
| Perez C, Pérez Zúñiga F, Garrido F, Reytor E, Portillo F, Pajares M. The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases. PLoS ONE. 2016;11:e0161672 pubmed publisher
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- western blot; human; fig s1
| Fokkelman M, Balcıoğlu H, Klip J, Yan K, Verbeek F, Danen E, et al. Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour. Sci Rep. 2016;6:31707 pubmed publisher
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- western blot; mouse; 1:5000; fig s2
| Saatcioglu H, Cuevas I, Castrillon D. Control of Oocyte Reawakening by Kit. PLoS Genet. 2016;12:e1006215 pubmed publisher
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- western blot; mouse; fig 7
| Furukawa Y, Tanemura K, Igarashi K, Ideta Otsuka M, Aisaki K, Kitajima S, et al. Learning and Memory Deficits in Male Adult Mice Treated with a Benzodiazepine Sleep-Inducing Drug during the Juvenile Period. Front Neurosci. 2016;10:339 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 1d
| Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, et al. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun. 2016;7:12431 pubmed publisher
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- western blot; human; fig 5
| Dhamad A, Zhou Z, Zhou J, Du Y. Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ER?) and Biochemical Characterization of the ER?-Hsp70 Interaction. PLoS ONE. 2016;11:e0160312 pubmed publisher
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- western blot; human; fig 3
| Fritsch K, Mernberger M, Nist A, Stiewe T, Brehm A, Jacob R. Galectin-3 interacts with components of the nuclear ribonucleoprotein complex. BMC Cancer. 2016;16:502 pubmed publisher
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- immunocytochemistry; human; 1:5000; fig 4
- western blot; human; 1:5000; fig 2
| Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016;214:155-66 pubmed publisher
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- western blot; human; 1:1000; fig 4
| Belvedere R, Bizzarro V, Forte G, Dal Piaz F, Parente L, Petrella A. Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway. Sci Rep. 2016;6:29660 pubmed publisher
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- western blot; mouse; 1:1000; fig 2
| Miles D, de Vries N, Gisler S, Lieftink C, Akhtar W, Gogola E, et al. TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming. Stem Cells. 2017;35:147-157 pubmed publisher
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- western blot; mouse; 1:1000; fig 4g
| Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann J, Manns M, et al. MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun. 2016;7:11916 pubmed publisher
|
- western blot; human; fig s3
| Bennesch M, Segala G, Wider D, Picard D. LSD1 engages a corepressor complex for the activation of the estrogen receptor ? by estrogen and cAMP. Nucleic Acids Res. 2016;44:8655-8670 pubmed
|
- western blot; mouse; 1:5000; fig 3
- western blot; African green monkey; 1:5000; fig 1
| Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
|
- immunocytochemistry; mouse; 1:400; loading ...; fig 3c
| Eymery A, Liu Z, Ozonov E, Stadler M, Peters A. The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos. Development. 2016;143:2767-79 pubmed publisher
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- western blot; mouse; 1:1000; fig 1
| Yin Y, Gao D, Wang Y, Wang Z, Wang X, Ye J, et al. Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci U S A. 2016;113:E3773-81 pubmed publisher
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- western blot; human; 1:10,000; fig 3
| Matsumura S, Kojidani T, Kamioka Y, Uchida S, Haraguchi T, Kimura A, et al. Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1. Nat Commun. 2016;7:ncomms11858 pubmed publisher
|
- immunohistochemistry; fruit fly ; fig 3
| Bergstralh D, Lovegrove H, Kujawiak I, Dawney N, Zhu J, Cooper S, et al. Pins is not required for spindle orientation in the Drosophila wing disc. Development. 2016;143:2573-81 pubmed publisher
|
- western blot; rat; 1:1000; fig 1
| Yin Y, Wang Y, Gao D, Ye J, Wang X, Fang L, et al. Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2. Sci Rep. 2016;6:27283 pubmed publisher
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- immunocytochemistry; mouse; 1:1000; fig 2
| van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed publisher
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- western blot; human; fig 5a
| Daubon T, Spuul P, Alonso F, Fremaux I, Genot E. VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells. J Cell Sci. 2016;129:2586-98 pubmed publisher
|
- western blot; human; 1:5000; fig 6
- western blot; mouse; 1:5000; fig s2
| Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed publisher
|
- western blot; mouse; 1:5000; fig 4
| Kobayashi E, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat Commun. 2016;7:11624 pubmed publisher
|
- western blot; bovine; 1:10,000; fig 2
| Umezu K, Hiradate Y, Oikawa T, Ishiguro H, Numabe T, Hara K, et al. Exogenous neurotensin modulates sperm function in Japanese Black cattle. J Reprod Dev. 2016;62:409-14 pubmed publisher
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- western blot; mouse; 1:1000; fig 5
| Kessler S, Laggai S, Van Wonterg E, Gemperlein K, Muller R, Haybaeck J, et al. Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. Front Physiol. 2016;7:147 pubmed publisher
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- western blot; human; fig 2
| Guinot A, Oeztuerk Winder F, Ventura J. miR-17-92/p38? Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression. Cancer Res. 2016;76:4012-22 pubmed publisher
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- western blot; mouse; fig 6
| de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed publisher
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- immunocytochemistry; human; 1:100; fig 4
| Chang C, Hsu W, Tsai J, Tang C, Tang T. CEP295 interacts with microtubules and is required for centriole elongation. J Cell Sci. 2016;129:2501-13 pubmed publisher
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- immunocytochemistry; human; 1:500; fig s1
| Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed publisher
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- western blot; mouse; fig 5
| Takenaka N, Nihata Y, Satoh T. Rac1 Activation Caused by Membrane Translocation of a Guanine Nucleotide Exchange Factor in Akt2-Mediated Insulin Signaling in Mouse Skeletal Muscle. PLoS ONE. 2016;11:e0155292 pubmed publisher
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- western blot; mouse; 1:5000; fig 4
| Marei H, Carpy A, Macek B, Malliri A. Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors. Cell Cycle. 2016;15:1961-74 pubmed publisher
|
- western blot; mouse; 1:2000; fig 1
| Riaz M, Raz Y, van Putten M, Paniagua Soriano G, Krom Y, Florea B, et al. PABPN1-Dependent mRNA Processing Induces Muscle Wasting. PLoS Genet. 2016;12:e1006031 pubmed publisher
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- western blot; human; 1:5000; fig 6
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- western blot; human; fig 3
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- western blot; human; fig 6
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- western blot; mouse; 1:1000; fig 1
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- western blot; rat; 1:1000; fig 1
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- immunohistochemistry; fruit fly ; 1:100; fig 1
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- western blot; mouse; 1:5000; fig 1
| Brüggen B, Kremser C, Bickert A, Ebel P, Vom Dorp K, Schultz K, et al. Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea. Eur J Neurosci. 2016;44:1700-13 pubmed publisher
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- immunocytochemistry; mouse; 1:500; fig 2
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- western blot; human; fig 3
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| Taguchi K, Takaku M, Egner P, Morita M, Kaneko T, Mashimo T, et al. Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity. Toxicol Sci. 2016;152:40-52 pubmed publisher
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- western blot; mouse; 1:5000; fig 1
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- western blot; human; fig 4
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- immunocytochemistry; human; fig 2
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- immunocytochemistry; human; fig 2
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- immunocytochemistry; human; 1:1000; fig 3
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- western blot; human; fig 5
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- immunocytochemistry; mouse; fig 2
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- western blot; human; fig 4
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- western blot; human; 1:5000; fig 1c
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- western blot; human; 1:20,000; fig 3g
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- western blot; human; 1:1000
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- western blot; mouse; 1:10,000; fig 3
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- western blot; human; fig 1
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- western blot; mouse; fig 3c
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- immunocytochemistry; mouse; fig 3
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- immunocytochemistry; human; fig 1
- immunocytochemistry; roundworm ; fig 2
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| Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher
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- western blot; mouse; 1:10,000; fig 1
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- western blot; human; fig 1
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- western blot; human; 1:5000; fig 6
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- immunohistochemistry; roundworm ; 1:200; fig 3
- western blot; roundworm ; 1:5000; fig 1
| Franz A, Pirson P, Pilger D, Halder S, Achuthankutty D, Kashkar H, et al. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. Nat Commun. 2016;7:10612 pubmed publisher
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- immunocytochemistry; longfin inshore squid; fig 1
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- western blot; human; 1:10,000; fig 1
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- western blot; human; 1:10,000; fig 1a
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- immunocytochemistry; mouse; 1:200; fig 4
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- western blot; human; fig 1
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- immunocytochemistry; human; 1:250
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- western blot; mouse; 1:1000; fig 3
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- immunocytochemistry; human; 1:500; fig 7
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- immunocytochemistry; long-nosed rat kangaroo; 1:500; loading ...; fig 1i
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- western blot; human; 1:5000; fig 2
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- western blot; human; fig 1
| Ge C, Che L, Du C. The UBC Domain Is Required for BRUCE to Promote BRIT1/MCPH1 Function in DSB Signaling and Repair Post Formation of BRUCE-USP8-BRIT1 Complex. PLoS ONE. 2015;10:e0144957 pubmed publisher
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- western blot; rat; 1:5000; fig s6
| Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed publisher
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- western blot; mouse; fig 4
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- western blot; mouse; 1:2500
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- immunocytochemistry; human; 1:1500; fig 1
- western blot; human; 1:1500; fig 1
- immunocytochemistry; mouse; 1:1500; fig 5
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- western blot; mouse; 1:5000
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- western blot; human; fig 2
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- western blot; mouse; 1:10,000; fig 4b
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- immunocytochemistry; human; fig 1
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- western blot; human; 1:30,000; fig 4
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| Garcia Manteiga J, Bonfiglio S, Folladori L, Malosio M, Lazarevic D, Stupka E, et al. REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation. Front Cell Neurosci. 2015;9:438 pubmed publisher
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- western blot; mouse; fig 2a
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- western blot; human; fig 1
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- western blot; mouse; fig 2
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- western blot; human; fig 4
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- immunohistochemistry - paraffin section; fruit fly ; 1:500; fig s5f
- western blot; fruit fly ; 1:1000; fig s5a
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- western blot; mouse; fig 1
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- western blot; mouse; fig 1a
| Iarriccio L, Manguán GarcÃa C, Pintado Berninches L, Mancheño J, Molina A, Perona R, et al. GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells. PLoS ONE. 2015;10:e0142980 pubmed publisher
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- western blot; chicken; 1:1000; fig 3
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- immunocytochemistry; mouse; fig 2
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| Stanojlović M, Guševac I, Grković I, Zlatković J, Mitrović N, Zarić M, et al. Effects of chronic cerebral hypoperfusion and low-dose progesterone treatment on apoptotic processes, expression and subcellular localization of key elements within Akt and Erk signaling pathways in rat hippocampus. Neuroscience. 2015;311:308-21 pubmed publisher
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- western blot; human; 1:1000; fig 4d
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- proximity ligation assay; human; fig 7
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- western blot; mouse; fig 4
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- western blot; mouse; fig 2
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- immunocytochemistry; fruit fly ; 1:50; fig s1
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- western blot; mouse; 1:5000; fig 6
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- western blot; human; fig 7b
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- western blot; human; 1:2000; fig 4
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- western blot; fruit fly ; 1:3000; fig 4
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- western blot; fruit fly ; 1:10,000; fig 3a
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- western blot; mouse; 1:5000; fig 1
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| Zhu L, Wang Z, Wang W, Wang C, Hua S, Su Z, et al. Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis. J Biol Chem. 2015;290:27053-66 pubmed publisher
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| Qiao Y, Lin S, Chen Y, Voon D, Zhu F, Chuang L, et al. RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer. Oncogene. 2016;35:2664-74 pubmed publisher
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- western blot; human; 1:1000; fig 1c
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- immunocytochemistry; mouse; fig 3
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- western blot; mouse; 1:1000; fig 4
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- western blot; human; 1:5000; fig 5
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- immunocytochemistry; human; 1:4000; fig s2
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- western blot; human; fig 4
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- western blot; human; 1:4000; fig 1
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- western blot; dogs; 1:10,000; fig 1a
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- western blot; mouse; 1:2000
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- immunocytochemistry; mouse; 1:500; fig 3
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- western blot; human; fig 1c
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- western blot; human; 1:7500; fig 4
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- western blot; human; 1:10,000; fig 1
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- western blot; human; fig 2
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- western blot; human; 1:1000; fig 3
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- immunoprecipitation; human; fig 3
- immunocytochemistry; human; 1:200; fig 3
- western blot; human; fig 3
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- immunohistochemistry; starlet sea anemone; 1:100; loading ...; fig 4a
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- immunocytochemistry; human; 1:2500; fig 7
- western blot; human; 1:5000; fig 6
| Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed publisher
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| Kim D, Yeom J, Lee B, Lee K, Bae J, Rhee S. Inhibition of discoidin domain receptor 2-mediated lung cancer cells progression by gold nanoparticle-aptamer-assisted delivery of peptides containing transmembrane-juxtamembrane 1/2 domain. Biochem Biophys Res Commun. 2015;464:392-5 pubmed publisher
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- western blot; rat; 1:5000; fig 2
| Rato L, Alves M, Dias T, Cavaco J, Oliveira P. Testicular Metabolic Reprogramming in Neonatal Streptozotocin-Induced Type 2 Diabetic Rats Impairs Glycolytic Flux and Promotes Glycogen Synthesis. J Diabetes Res. 2015;2015:973142 pubmed publisher
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- western blot; mouse; 1:2500; fig 3
| Selvaraj D, Gangadharan V, Michalski C, Kurejova M, Stösser S, Srivastava K, et al. A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain. Cancer Cell. 2015;27:780-96 pubmed publisher
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- western blot; human; 1:10,000; fig 4
| Luo W, Liu W, Hu X, Hanna M, Caravaca A, Paul S. Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody. Sci Rep. 2015;5:11161 pubmed publisher
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- immunocytochemistry; human; 1:400; fig s1
- western blot; human; 1:10,000; fig 4
| Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infect Immun. 2015;83:3268-80 pubmed publisher
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| Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher
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- immunocytochemistry; human; 1:2500; fig 3
| Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed publisher
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- western blot; human; fig 1d
| Urban B, Collard T, Eagle C, Southern S, Greenhough A, Hamdollah Zadeh M, et al. BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling. Gut. 2016;65:1151-64 pubmed publisher
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- western blot; human; fig 4
| Kim J, Kim B, Lee H, Thakkar S, Babbitt D, Eguchi S, et al. Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells. Am J Physiol Heart Circ Physiol. 2015;309:H425-33 pubmed publisher
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- immunocytochemistry; African green monkey; 1:250; loading ...; fig 3A
- western blot; African green monkey; 1:1000; loading ...; fig 3B
| Herms A, Bosch M, Reddy B, Schieber N, Fajardo A, Rupérez C, et al. AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation. Nat Commun. 2015;6:7176 pubmed publisher
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- western blot; human; fig 4
| Alonso Curbelo D, Osterloh L, Cañón E, Calvo T, MartÃnez Herranz R, Karras P, et al. RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development. Oncotarget. 2015;6:11848-62 pubmed
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- immunocytochemistry; human; fig s4
- western blot; human; fig s7
| Panic M, Hata S, Neuner A, Schiebel E. The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes. PLoS Genet. 2015;11:e1005243 pubmed publisher
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- immunocytochemistry; dogs
- western blot; dogs
| Reales E, Bernabé Rubio M, Casares Arias J, Rentero C, Fernández Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed publisher
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- western blot; human; 1:1000
| Tanas M, Ma S, Jadaan F, Ng C, Weigelt B, Reis Filho J, et al. Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein. Oncogene. 2016;35:929-38 pubmed publisher
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- western blot; human; fig 1
| Moldovan J, Moran J. The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition. PLoS Genet. 2015;11:e1005121 pubmed publisher
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- western blot; Xenopus laevis; 1:20,000
| Breznau E, Semack A, Higashi T, Miller A. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells. Mol Biol Cell. 2015;26:2439-55 pubmed publisher
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- western blot; mouse; fig 1
| Thress K, Paweletz C, Felip E, Cho B, Stetson D, Dougherty B, et al. Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M. Nat Med. 2015;21:560-2 pubmed publisher
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- western blot; mouse; fig 3
| Williamson R, Cowell C, Reville T, Roper J, Rendall T, Bass M. Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking. J Biol Chem. 2015;290:15437-49 pubmed publisher
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- western blot; mouse; 1:1000; fig s1
| Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, et al. Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice. Nat Commun. 2015;6:7035 pubmed publisher
|
- immunohistochemistry; California sea hare; 1:200
| Carrigan I, Croll R, Wyeth R. Morphology, innervation, and peripheral sensory cells of the siphon of aplysia californica. J Comp Neurol. 2015;523:2409-25 pubmed publisher
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- western blot; mouse; 1:2000; fig 2
| Vicuña L, Strochlic D, Latremoliere A, Bali K, Simonetti M, Husainie D, et al. The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med. 2015;21:518-23 pubmed publisher
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- western blot; human; fig 1
| Gago Fuentes R, Fernández Puente P, Megias D, Carpintero Fernández P, Mateos J, Acea B, et al. Proteomic Analysis of Connexin 43 Reveals Novel Interactors Related to Osteoarthritis. Mol Cell Proteomics. 2015;14:1831-45 pubmed publisher
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- western blot; human; fig s7
| Ceballos Chávez M, Subtil RodrÃguez A, Giannopoulou E, Soronellas D, Vázquez Chávez E, Vicent G, et al. The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers. PLoS Genet. 2015;11:e1005174 pubmed publisher
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- western blot; human; 1:2500; fig s4e
| Koizume S, Ito S, Nakamura Y, Yoshihara M, Furuya M, Yamada R, et al. Lipid starvation and hypoxia synergistically activate ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer. Mol Cancer. 2015;14:77 pubmed publisher
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| Tebbi A, Guittet O, Tuphile K, Cabrié A, Lepoivre M. Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis. J Biol Chem. 2015;290:14077-90 pubmed publisher
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- immunocytochemistry; human; 1:250
| Hori A, Peddie C, Collinson L, Toda T. Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly. Mol Biol Cell. 2015;26:2005-19 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1b
| Chen A, Akhshi T, Lavoie B, Wilde A. Importin β2 Mediates the Spatio-temporal Regulation of Anillin through a Noncanonical Nuclear Localization Signal. J Biol Chem. 2015;290:13500-9 pubmed publisher
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- western blot; mouse; 0.5 ug/ml; fig 1
- western blot; human; 0.5 ug/ml; fig 1
| Tabariès S, Annis M, Hsu B, Tam C, Savage P, Park M, et al. Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis. Oncotarget. 2015;6:9476-87 pubmed
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- western blot; mouse; 1.2 ug/ml
| Dorgau B, Herrling R, Schultz K, Greb H, Segelken J, Ströh S, et al. Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions. J Comp Neurol. 2015;523:2062-81 pubmed publisher
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- western blot; mouse; 1:1000; fig 4a
| Li L, Xu Z, Liu G, Xu C, Wang Z, Li X, et al. Expression of 1N3R-Tau isoform inhibits cell proliferation by inducing S phase arrest in N2a cells. PLoS ONE. 2015;10:e0119865 pubmed publisher
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- western blot; mouse; 1:5000
| Shin C, Grossmann A, Holmen S, Robinson J. The BRAF kinase domain promotes the development of gliomas in vivo. Genes Cancer. 2015;6:9-18 pubmed
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| Ainsua Enrich E, Serrano Candelas E, Ãlvarez Errico D, Picado C, Sayós J, Rivera J, et al. The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival. J Immunol. 2015;194:4309-18 pubmed publisher
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- western blot; fruit fly ; fig s3
| Takada S, Collins E, Kurahashi K. The FHA domain determines Drosophila Chk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses. Mol Biol Cell. 2015;26:1811-28 pubmed publisher
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| Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed publisher
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- western blot; human; fig 1
| Kobayashi A, Hashizume C, Dowaki T, Wong R. Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A. Cell Cycle. 2015;14:1447-58 pubmed publisher
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- western blot; human; fig s24
| Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed publisher
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- western blot; mouse; 1:2000; fig 5
| Tassinari V, Campolo F, Cesarini V, Todaro F, Dolci S, Rossi P. Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand. Cell Death Dis. 2015;6:e1688 pubmed publisher
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- western blot; mouse; fig 1
| Cheng H, Chern Y, Chen I, Liu C, Li S, Chun S, et al. Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown. PLoS Genet. 2015;11:e1005043 pubmed publisher
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- western blot; human; fig 1
| Wengrod J, Wang D, Weiss S, Zhong H, Osman I, Gardner L. Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Sci Signal. 2015;8:ra27 pubmed publisher
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- western blot; mouse; fig 3
| Gillespie M, Gold E, Ramsey S, Podolsky I, Aderem A, Ranish J. An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux. EMBO J. 2015;34:1244-58 pubmed publisher
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- western blot; human; 1:1000
| Tsuru A, Setoguchi T, Matsunoshita Y, Nagao Kitamoto H, Nagano S, Yokouchi M, et al. Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression. Br J Cancer. 2015;112:1232-40 pubmed publisher
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- western blot; human; fig 2
| Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, et al. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci. 2015;18:501-10 pubmed publisher
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- chromatin immunoprecipitation; human; 1:10,000
| Carvallo L, Lopez L, Che F, Lim J, Eugenin E, Williams D, et al. Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes. J Immunol. 2015;194:3246-58 pubmed publisher
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| Banks C, Boanca G, Lee Z, Florens L, Washburn M. Proteins interacting with cloning scars: a source of false positive protein-protein interactions. Sci Rep. 2015;5:8530 pubmed publisher
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- western blot; mouse; 1:1000; fig 6,7
| Beaven R, Dzhindzhev N, Qu Y, Hahn I, Dajas Bailador F, Ohkura H, et al. Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system. Mol Biol Cell. 2015;26:1491-508 pubmed publisher
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| Ito T, Taniguchi H, Fukagai K, Okamuro S, Kobayashi A. Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis. PLoS ONE. 2015;10:e0118336 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:750; fig 5
- immunocytochemistry; human; 1:1000; fig 1
| Morris E, Assi K, Salh B, Dedhar S. Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum. Sci Rep. 2015;5:8389 pubmed publisher
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- western blot; human; 1:1000; fig 5
| Kondapalli K, Llongueras J, Capilla González V, Prasad H, Hack A, Smith C, et al. A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastoma. Nat Commun. 2015;6:6289 pubmed publisher
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- western blot; mouse; 1:2000
| Chen J, Ren J, Jing Q, Lu S, Zhang Y, Liu Y, et al. TSH/TSHR Signaling Suppresses Fatty Acid Synthase (FASN) Expression in Adipocytes. J Cell Physiol. 2015;230:2233-9 pubmed publisher
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- immunohistochemistry; fruit fly ; 1:2000
| Okumura M, Sakuma C, Miura M, Chihara T. Linking cell surface receptors to microtubules: tubulin folding cofactor D mediates Dscam functions during neuronal morphogenesis. J Neurosci. 2015;35:1979-90 pubmed publisher
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- western blot; zebrafish ; 1:2000; fig 4
| Horstick E, Jordan D, Bergeron S, Tabor K, Serpe M, Feldman B, et al. Increased functional protein expression using nucleotide sequence features enriched in highly expressed genes in zebrafish. Nucleic Acids Res. 2015;43:e48 pubmed publisher
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- western blot; human; fig 1
| Santhana Kumar K, Tripolitsioti D, Ma M, Grählert J, Egli K, Fiaschetti G, et al. The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma. Springerplus. 2015;4:19 pubmed publisher
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- western blot; bovine; fig s4
| Marsolier J, Perichon M, Debarry J, Villoutreix B, Chluba J, Lopez T, et al. Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation. Nature. 2015;520:378-82 pubmed publisher
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- western blot; human; 1:2000
| López de Figueroa P, Lotz M, Blanco F, Caramés B. Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes. Arthritis Rheumatol. 2015;67:966-76 pubmed publisher
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- western blot; human; fig 8
| Thomas Y, Peter M, Mechali F, Blanchard J, Coux O, Baldin V. Kizuna is a novel mitotic substrate for CDC25B phosphatase. Cell Cycle. 2014;13:3867-77 pubmed publisher
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- western blot; human; fig s2
| Brandstaetter H, Kishi Itakura C, Tumbarello D, Manstein D, Buss F. Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy. 2014;10:2310-23 pubmed publisher
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- immunocytochemistry; mouse; 1:1000
- western blot; mouse; 1:5000
| Kim J, Ishiguro K, Nambu A, Akiyoshi B, Yokobayashi S, Kagami A, et al. Meikin is a conserved regulator of meiosis-I-specific kinetochore function. Nature. 2015;517:466-71 pubmed publisher
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- immunoprecipitation; mouse; 1:2000-1:4000; fig 5
| Imajo M, Ebisuya M, Nishida E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat Cell Biol. 2015;17:7-19 pubmed publisher
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| Ling X, Xu C, Fan C, Zhong K, Li F, Wang X. FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX. Cancer Res. 2014;74:7487-97 pubmed publisher
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- western blot; mouse; 1:5000; fig 6
| Qiao X, Roth I, Féraille E, Hasler U. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle. 2014;13:3059-75 pubmed publisher
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| Li M, Bian C, Yu X. Poly(ADP-ribosyl)ation is recognized by ECT2 during mitosis. Cell Cycle. 2014;13:2944-51 pubmed publisher
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- immunocytochemistry; mouse
| Hoon J, Li H, Koh C. POPX2 phosphatase regulates cell polarity and centrosome placement. Cell Cycle. 2014;13:2459-68 pubmed publisher
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- western blot; mouse; 1:20,000; fig 1
| Meng L, Ward A, Chun S, Bennett C, Beaudet A, Rigo F. Towards a therapy for Angelman syndrome by targeting a long non-coding RNA. Nature. 2015;518:409-12 pubmed publisher
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- western blot; human; fig 2
| Pickholtz I, Saadyan S, Keshet G, Wang V, Cohen R, Bouwman P, et al. Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells. Oncotarget. 2014;5:11827-46 pubmed
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- immunocytochemistry; rat; 1:250; fig 1
- western blot; rat; 1:1000; fig 1
| Leyk J, Goldbaum O, Noack M, Richter Landsberg C. Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance. J Mol Neurosci. 2015;55:1031-46 pubmed publisher
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| Green C, Fraser S, Day M. Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro. Hum Reprod. 2015;30:284-98 pubmed publisher
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- western blot; human; 1:10,000
| Boscia F, Passaro C, Gigantino V, Perdonà S, Franco R, Portella G, et al. High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness. J Cell Physiol. 2015;230:1290-7 pubmed publisher
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- western blot; mouse; 1:10,000
| Kararigas G, Fliegner D, Forler S, Klein O, Schubert C, Gustafsson J, et al. Comparative proteomic analysis reveals sex and estrogen receptor β effects in the pressure overloaded heart. J Proteome Res. 2014;13:5829-36 pubmed publisher
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- western blot; fruit fly ; fig 1
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- western blot; human; 1:5000; fig 5
| Husedzinovic A, Neumann B, Reymann J, Draeger Meurer S, Chari A, Erfle H, et al. The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization. Mol Biol Cell. 2015;26:161-71 pubmed publisher
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- western blot; African green monkey; fig 4
| Korobko E, Kiselev S, Korobko I. Characterization of Rabaptin-5 γ isoform. Biochemistry (Mosc). 2014;79:856-64 pubmed publisher
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- western blot; mouse; 1:2500
| MartÃnez Vega R, Garrido F, Partearroyo T, Cediel R, Zeisel S, MartÃnez Ãlvarez C, et al. Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism. FASEB J. 2015;29:418-32 pubmed publisher
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- western blot; mouse; 1:5000; fig 3
| Katz Y, Li F, Lambert N, Sokol E, Tam W, Cheng A, et al. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. elife. 2014;3:e03915 pubmed publisher
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- western blot; mouse; 1:5000
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- immunocytochemistry; Hydractinia echinata; 1:1000
| Kraus Y, Flici H, Hensel K, Plickert G, Leitz T, Frank U. The embryonic development of the cnidarian Hydractinia echinata. Evol Dev. 2014;16:323-38 pubmed publisher
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- immunocytochemistry; human; fig 5
- western blot; human; fig 5
| Mardilovich K, Gabrielsen M, McGarry L, Orange C, Patel R, Shanks E, et al. Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Mol Cancer Ther. 2015;14:246-58 pubmed publisher
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- western blot; human; fig 3
| Bultema J, Boyle J, Malenke P, Martin F, Dell Angelica E, Cheney R, et al. Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomes. J Biol Chem. 2014;289:33513-28 pubmed publisher
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- immunocytochemistry; human; 1:1000
- western blot; human; 1:1000
| Agircan F, Schiebel E. Sensors at centrosomes reveal determinants of local separase activity. PLoS Genet. 2014;10:e1004672 pubmed publisher
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- immunohistochemistry; Rhynchospora tenuis; 1:40; fig s2
- immunohistochemistry; Rhynchospora pubera
| Cabral G, Marques A, Schubert V, Pedrosa Harand A, Schlögelhofer P. Chiasmatic and achiasmatic inverted meiosis of plants with holocentric chromosomes. Nat Commun. 2014;5:5070 pubmed publisher
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- western blot; human; fig 4
| Reese J, Suman V, Subramaniam M, Wu X, Negron V, Gingery A, et al. ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer. BMC Cancer. 2014;14:749 pubmed publisher
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- western blot; human; 1:1000; fig 2
| Ilagan J, Ramakrishnan A, Hayes B, Murphy M, Zebari A, Bradley P, et al. U2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res. 2015;25:14-26 pubmed publisher
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| Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, et al. β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer. Cell Death Differ. 2015;22:298-310 pubmed publisher
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- immunocytochemistry; human; 1:5000; fig 1
- western blot; human; 1:5000; fig 3
| Chan Y, West S. Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nat Commun. 2014;5:4844 pubmed publisher
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- western blot; human; 1:2000
| Ribeiro Varandas E, Pereira H, Monteiro S, Neves E, Brito L, Ferreira R, et al. Bisphenol A disrupts transcription and decreases viability in aging vascular endothelial cells. Int J Mol Sci. 2014;15:15791-805 pubmed publisher
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- western blot; rat; 1:2500
| Rocha C, Martins A, Rato L, Silva B, Oliveira P, Alves M. Melatonin alters the glycolytic profile of Sertoli cells: implications for male fertility. Mol Hum Reprod. 2014;20:1067-76 pubmed publisher
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- immunoprecipitation; human; fig 3
| Tao L, Chen C, Song H, Piccioni M, Shi G, Li B. Deubiquitination and stabilization of IL-33 by USP21. Int J Clin Exp Pathol. 2014;7:4930-7 pubmed
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| Liu J, Zheng L, Ma L, Wang B, Zhao Y, Wu N, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014;25:1154-1160 pubmed publisher
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- immunocytochemistry; mouse; 1:100; fig 5
| Rotunno M, Auclair J, Maniatis S, Shaffer S, AGAR J, Bosco D. Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis. J Biol Chem. 2014;289:28527-38 pubmed publisher
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| Peng M, Emmadi R, Wang Z, Wiley E, Gann P, Khan S, et al. PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors. Oncotarget. 2014;5:6038-48 pubmed
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| Ishii H, Saitoh M, Sakamoto K, Kondo T, Katoh R, Tanaka S, et al. Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms. J Biol Chem. 2014;289:27386-99 pubmed publisher
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- western blot; human; 1:5000
| Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, et al. PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma. Mol Oncol. 2015;9:78-92 pubmed publisher
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- western blot; mouse; 1:10,000; fig 2
- western blot; human; 1:10,000; fig 1
| Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed publisher
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- western blot; Aspergillus sp.; 1:1000
| James S, Banta T, Barra J, Ciraku L, Coile C, Cuda Z, et al. Restraint of the G2/M transition by the SR/RRM family mRNA shuttling binding protein SNXAHRB1 in Aspergillus nidulans. Genetics. 2014;198:617-33 pubmed publisher
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- western blot; mouse; 1:10,000; fig 5
| Lee Y, Santé J, Comerci C, Cyge B, Menezes L, Li F, et al. Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function. Mol Biol Cell. 2014;25:2919-33 pubmed publisher
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| Isogaya K, Koinuma D, Tsutsumi S, Saito R, Miyazawa K, Aburatani H, et al. A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression. Cell Res. 2014;24:994-1008 pubmed publisher
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- western blot; human; fig s1
| Smith C, Matheson T, Trombly D, Sun X, Campeau E, Han X, et al. A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli. Mol Biol Cell. 2014;25:2866-81 pubmed publisher
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- western blot; fruit fly ; 1:5000; fig s1
| Galletta B, Guillen R, Fagerstrom C, Brownlee C, Lerit D, Megraw T, et al. Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies. Mol Biol Cell. 2014;25:2682-94 pubmed publisher
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- western blot; human; fig 3
| Nickerson K, Homer C, Kessler S, Dixon L, Kabi A, Gordon I, et al. The dietary polysaccharide maltodextrin promotes Salmonella survival and mucosal colonization in mice. PLoS ONE. 2014;9:e101789 pubmed publisher
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- western blot; mouse; 1:5000
| Lodato S, Molyneaux B, Zuccaro E, Goff L, Chen H, Yuan W, et al. Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014;17:1046-54 pubmed publisher
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- western blot; mouse; 1:10,000; fig 4
| Hopkins J, Hwang G, Jacob J, Sapp N, Bedigian R, Oka K, et al. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet. 2014;10:e1004413 pubmed publisher
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- western blot; human; fig s4
| Manguan García C, Pintado Berninches L, Carrillo J, Machado Pinilla R, Sastre L, Perez Quilis C, et al. Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells. PLoS ONE. 2014;9:e101424 pubmed publisher
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- western blot; mouse; fig 1
| Takeda A, Oberoi Khanuja T, Glatz G, Schulenburg K, Scholz R, Carpy A, et al. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1. EMBO J. 2014;33:1784-801 pubmed publisher
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- immunocytochemistry; human
- western blot; human
| O Rourke B, Gomez Ferreria M, Berk R, Hackl A, Nicholas M, O Rourke S, et al. Cep192 controls the balance of centrosome and non-centrosomal microtubules during interphase. PLoS ONE. 2014;9:e101001 pubmed publisher
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| Kim D, Birendra K, Zhu W, Motamedchaboki K, Doye V, Roux K. Probing nuclear pore complex architecture with proximity-dependent biotinylation. Proc Natl Acad Sci U S A. 2014;111:E2453-61 pubmed publisher
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| Soares F, Tattoli I, Rahman M, Robertson S, Belcheva A, Liu D, et al. The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. J Biol Chem. 2014;289:19317-30 pubmed publisher
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- western blot; pigs ; 1:10,000
- immunocytochemistry; African green monkey; 1:10,000
| Kielar M, Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci. 2014;17:923-33 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:500
| Li R, Tan J, Chen L, Feng J, Liang W, Guo X, et al. Iqcg is essential for sperm flagellum formation in mice. PLoS ONE. 2014;9:e98053 pubmed publisher
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- immunocytochemistry; African green monkey
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- western blot; human
- western blot; mouse
| Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
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- western blot; human; 1:15,000
| Zavodszky E, Seaman M, Moreau K, Jimenez Sanchez M, Breusegem S, Harbour M, et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun. 2014;5:3828 pubmed publisher
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| Shaw Hallgren G, Chmielarska Masoumi K, Zarrizi R, Hellman U, Karlsson P, Helou K, et al. Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells. PLoS ONE. 2014;9:e96506 pubmed publisher
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- immunocytochemistry; human; 1:1000; fig 2
- western blot; human; 1:10,000; fig 2
| Thoresen S, Campsteijn C, Vietri M, Schink K, Liestøl K, Andersen J, et al. ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4. Nat Cell Biol. 2014;16:550-60 pubmed publisher
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| Garimella S, Gehlhaus K, Dine J, Pitt J, Grandin M, Chakka S, et al. Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening. Breast Cancer Res. 2014;16:R41 pubmed publisher
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| Hayes S, Hng K, Clark P, Thistlethwaite F, Hawkins R, Ang Y. Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens. World J Gastroenterol. 2014;20:4011-6 pubmed publisher
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| Touat Hamici Z, Legrain Y, Bulteau A, Chavatte L. Selective up-regulation of human selenoproteins in response to oxidative stress. J Biol Chem. 2014;289:14750-61 pubmed publisher
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| Han X, Cheng D, Song F, Zeng T, An L, Xie K. Decelerated transport and its mechanism of 2,5-hexanedione on middle-molecular-weight neurofilament in rat dorsal root ganglia cells. Neuroscience. 2014;269:192-8 pubmed publisher
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- western blot; mouse; 1:1000
| Feuer S, Liu X, Donjacour A, Lin W, Simbulan R, Giritharan G, et al. Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis. Endocrinology. 2014;155:1956-69 pubmed publisher
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- immunocytochemistry; human; 1:200
- western blot; human
| Kuo P, Huang Y, Hsieh C, Lee J, Lin B, Hung L. STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells. PLoS ONE. 2014;9:e93303 pubmed publisher
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- western blot; human; 1:1000
| Rennoll S, Scott S, Yochum G. Targeted repression of AXIN2 and MYC gene expression using designer TALEs. Biochem Biophys Res Commun. 2014;446:1120-5 pubmed publisher
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- immunocytochemistry; human
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- western blot; pigs
- western blot; human
| Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed publisher
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| Herve D, Philippi A, Belbouab R, Zerah M, Chabrier S, Collardeau Frachon S, et al. Loss of ?1?1 soluble guanylate cyclase, the major nitric oxide receptor, leads to moyamoya and achalasia. Am J Hum Genet. 2014;94:385-94 pubmed publisher
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- western blot; mouse; 1:1000
| Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, et al. Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation. J Biol Chem. 2014;289:9865-79 pubmed publisher
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| Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed publisher
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| Ryszawy D, Sarna M, Rak M, Szpak K, Kedracka Krok S, Michalik M, et al. Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer. Carcinogenesis. 2014;35:1920-30 pubmed publisher
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| Wong Y, Holzbaur E. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci. 2014;34:1293-305 pubmed publisher
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| Xu C, Fan C, Wang X. Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase. Oncogene. 2015;34:281-9 pubmed publisher
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- western blot; rat; 1:5000
| Sike A, Nagy E, Vedelek B, Pusztai D, Szerémy P, Venetianer A, et al. mRNA levels of related Abcb genes change opposite to each other upon histone deacetylase inhibition in drug-resistant rat hepatoma cells. PLoS ONE. 2014;9:e84915 pubmed publisher
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- western blot; roundworm ; fig 6.5
| Manil Ségalen M, Culetto E, Legouis R, Lefebvre C. Interactions between endosomal maturation and autophagy: analysis of ESCRT machinery during Caenorhabditis elegans development. Methods Enzymol. 2014;534:93-118 pubmed publisher
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- immunocytochemistry; human
| Klinger M, Wang W, Kuhns S, Bärenz F, Dräger Meurer S, Pereira G, et al. The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone. Mol Biol Cell. 2014;25:495-507 pubmed publisher
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| Sharma Walia N, Chandran K, Patel K, Veettil M, Marginean A. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol. 2014;88:2131-56 pubmed publisher
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| Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, et al. HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. PLoS Biol. 2013;11:e1001717 pubmed publisher
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- western blot; human; 1:1000
| Rennoll S, Konsavage W, Yochum G. Nuclear AXIN2 represses MYC gene expression. Biochem Biophys Res Commun. 2014;443:217-22 pubmed publisher
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- western blot; mouse; fig 6
| Tan S, Shui G, Zhou J, Shi Y, Huang J, Xia D, et al. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. Autophagy. 2014;10:226-42 pubmed publisher
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- western blot; rat; 1:5000
| Alves M, Martins A, Vaz C, Correia S, Moreira P, Oliveira P, et al. Metformin and male reproduction: effects on Sertoli cell metabolism. Br J Pharmacol. 2014;171:1033-42 pubmed publisher
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- western blot; human; fig 3
| Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods Mol Biol. 2014;1087:103-14 pubmed publisher
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- western blot; mouse; 1:10 000
| Garcia E, Santana Martínez R, Silva Islas C, Colín González A, Galvan Arzate S, Heras Y, et al. S-allyl cysteine protects against MPTP-induced striatal and nigral oxidative neurotoxicity in mice: participation of Nrf2. Free Radic Res. 2014;48:159-67 pubmed publisher
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| Aukkarasongsup P, Haruyama N, Matsumoto T, Shiga M, Moriyama K. Periostin inhibits hypoxia-induced apoptosis in human periodontal ligament cells via TGF-? signaling. Biochem Biophys Res Commun. 2013;441:126-32 pubmed publisher
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- immunocytochemistry; human
- western blot; human
| Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed publisher
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- immunocytochemistry; human
| Hashizume C, Moyori A, Kobayashi A, Yamakoshi N, Endo A, Wong R. Nucleoporin Nup62 maintains centrosome homeostasis. Cell Cycle. 2013;12:3804-16 pubmed publisher
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- western blot; human; fig 5
| Martinez Sanchez A, Murphy C. miR-1247 functions by targeting cartilage transcription factor SOX9. J Biol Chem. 2013;288:30802-14 pubmed publisher
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- western blot; mouse; 1:5000
| Kim Y, Zheng Y. Generation and characterization of a conditional deletion allele for Lmna in mice. Biochem Biophys Res Commun. 2013;440:8-13 pubmed publisher
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- western blot; human; 1:5000
| Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed publisher
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| Horton J, Stefanick D, Gassman N, Williams J, Gabel S, Cuneo M, et al. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. DNA Repair (Amst). 2013;12:774-85 pubmed publisher
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- western blot; mouse; 1:10,000
| Yuki K, Yoshida T, Miyake S, Tsubota K, Ozawa Y. Neuroprotective role of superoxide dismutase 1 in retinal ganglion cells and inner nuclear layer cells against N-methyl-d-aspartate-induced cytotoxicity. Exp Eye Res. 2013;115:230-8 pubmed publisher
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- western blot; human; fig 1a
| Alfonso Pérez T, Domínguez Sánchez M, Garcia Dominguez M, Reyes J. Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis. Oncogene. 2014;33:3064-74 pubmed publisher
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| Walser R, Burke J, Gogvadze E, Bohnacker T, Zhang X, Hess D, et al. PKC? phosphorylates PI3K? to activate it and release it from GPCR control. PLoS Biol. 2013;11:e1001587 pubmed publisher
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- western blot; mouse; 1:500
| Zhang L, Wahlin K, Li Y, Masuda T, Yang Z, Zack D, et al. RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. Mol Vis. 2013;19:1371-86 pubmed
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| Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature. 2013;498:492-6 pubmed publisher
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- immunocytochemistry; Xenopus laevis; 1:100
- western blot; Xenopus laevis; 1 ug/ml
| Samwer M, Dehne H, Spira F, Kollmar M, Gerlich D, Urlaub H, et al. The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J. 2013;32:1886-902 pubmed publisher
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- western blot; mouse
- western blot; human
| Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed publisher
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- western blot; mouse; 1:5000; fig s4
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- western blot; human; fig 3
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- western blot; mouse; fig s11
| Reginensi A, Scott R, Gregorieff A, Bagherie Lachidan M, Chung C, Lim D, et al. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. PLoS Genet. 2013;9:e1003380 pubmed publisher
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- immunocytochemistry; mouse
| Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, et al. NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells. 2013;31:1278-86 pubmed publisher
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- immunohistochemistry; Xenopus laevis; 1:1000
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- immunocytochemistry; mouse
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- western blot; rat; 1:1000
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- immunocytochemistry; human
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| Tattoli I, Philpott D, Girardin S. The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole. Biol Open. 2012;1:1215-25 pubmed publisher
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| Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed publisher
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| Fan C, Lum M, Xu C, Black J, Wang X. Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response. J Biol Chem. 2013;288:1674-84 pubmed publisher
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| Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed publisher
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- immunocytochemistry; human; 1:200
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- immunocytochemistry; human; 1:3000
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| Coffey K, Blackburn T, Cook S, Golding B, Griffin R, Hardcastle I, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS ONE. 2012;7:e45539 pubmed publisher
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- immunocytochemistry; human
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