product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-α-Tubulin antibody produced in mouse
catalog :
T9026
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DM1A
reactivity :
longfin inshore squid, Rhynchospora pubera, long-nosed rat kangaroo, Aspergillus sp., Hydractinia echinata, red rock crab, rye, California sea hare, Rhynchospora tenuis, Japanese rice fish, African green monkey, marine lamprey, starlet sea anemone, human, mouse, rat, dogs, chicken, bovine, pigs , zebrafish , fruit fly , Xenopus laevis, roundworm
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay
more info or order :
citations: 2915
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:10,000; loading ...; fig 2b
Ikari S, Yang Q, Lu S, Liu Y, Hao F, Tong G, et al. Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations. Antioxidants (Basel). 2021;10: pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 4g
  • western blot; human; 1:5000; loading ...; fig 1d, 1g
Wang L, Rajah A, Brown C, McCaffrey L. CD13 orients the apical-basal polarity axis necessary for lumen formation. Nat Commun. 2021;12:4697 pubmed publisher
  • immunocytochemistry; human; 1:250; loading ...; fig 5a
Watson A, Grant A, Parker S, Hill S, Whalen M, Chakrabarti J, et al. Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning. Cell Rep. 2021;35:109293 pubmed publisher
  • western blot; mouse; loading ...; fig 8b
Ramos Morales E, Bayam E, Del Pozo Rodríguez J, Salinas Giegé T, Marek M, Tilly P, et al. The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination. Nucleic Acids Res. 2021;49:6529-6548 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 2a
Kildey K, Gandhi N, Sahin K, Shah E, Boittier E, Duijf P, et al. Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy. Commun Biol. 2021;4:638 pubmed publisher
  • western blot; human; loading ...; fig 1b
Nakajima W, Miyazaki K, Asano Y, Kubota S, Tanaka N. Krüppel-Like Factor 4 and Its Activator APTO-253 Induce NOXA-Mediated, p53-Independent Apoptosis in Triple-Negative Breast Cancer Cells. Genes (Basel). 2021;12: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2h
Kariya Y, Oyama M, Suzuki T, Kariya Y. αvβ3 Integrin induces partial EMT independent of TGF-β signaling. Commun Biol. 2021;4:490 pubmed publisher
  • western blot; human; 1:2000; fig s5a
Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed publisher
  • western blot; human; fig 2c, 2d
Li T, Huang T, Du M, Chen X, Du F, Ren J, et al. Phosphorylation and chromatin tethering prevent cGAS activation during mitosis. Science. 2021;371: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1s2a
Vergarajauregui S, Becker R, Steffen U, Sharkova M, Esser T, Petzold J, et al. AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:4000; loading ...; fig 2a
Fomicheva M, Macara I. Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation. elife. 2020;9: pubmed publisher
  • western blot; mouse; loading ...; fig 1d
Yan J, Bengtson C, Buchthal B, Hagenston A, Bading H. Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants. Science. 2020;370: pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 5s3a
Rogerson C, Ogden S, Britton E, Ang Y, Sharrocks A. Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 5d
Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4a
Berges R, Tchoghandjian A, Serge A, Honore S, Figarella Branger D, Bachmann F, et al. EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis. Oncotarget. 2020;11:759-774 pubmed publisher
  • western blot; mouse; 1:8000; loading ...; fig s7a
Nagaoka S, Nakaki F, Miyauchi H, Nosaka Y, Ohta H, Yabuta Y, et al. ZGLP1 is a determinant for the oogenic fate in mice. Science. 2020;: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 6b
Bodrug T, Wilson Kubalek E, Nithianantham S, Thompson A, Alfieri A, Gaska I, et al. The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. elife. 2020;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3a
Lehmann M, Lukonin I, Noe F, Schmoranzer J, Clementi C, Loerke D, et al. Nanoscale coupling of endocytic pit growth and stability. Sci Adv. 2019;5:eaax5775 pubmed publisher
  • western blot; human; loading ...; fig s1c
Larson G, Tran V, Yu S, Cai Y, Higgins C, Smith D, et al. EPS8 Facilitates Uncoating of Influenza A Virus. Cell Rep. 2019;29:2175-2183.e4 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 7a
  • western blot; mouse; 1:2000; loading ...; fig 6a
Vohnoutka R, Gulvady A, Goreczny G, Alpha K, Handelman S, Sexton J, et al. The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts. Mol Biol Cell. 2019;30:3037-3056 pubmed publisher
  • western blot; mouse; 1:10,000; loading ...; fig s7g
Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4c
Morishita H, Zhao Y, Tamura N, Nishimura T, Kanda Y, Sakamaki Y, et al. A critical role of VMP1 in lipoprotein secretion. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 2d
Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2c
Wang R, Yu R, Zhu C, Lin H, Lu X, Wang H. Tubulin detyrosination promotes human trophoblast syncytium formation. J Mol Cell Biol. 2019;: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1b
Hartono -, Hazawa M, Lim K, Dewi F, Kobayashi A, Wong R. Nucleoporin Nup58 localizes to centrosomes and mid-bodies during mitosis. Cell Div. 2019;14:7 pubmed publisher
  • western blot; human; loading ...; fig 6a
Dorsch L, Schuldt M, dos Remedios C, Schinkel A, de Jong P, Michels M, et al. Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy. Cells. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig s6b
Marcus J, Bejerano Sagie M, Patterson N, Bagchi S, Verkhusha V, Connolly D, et al. Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions. Oncogene. 2019;38:5839-5859 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 3d
Sajini A, Choudhury N, Wagner R, Bornelöv S, Selmi T, Spanos C, et al. Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation. Nat Commun. 2019;10:2550 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig s1f
Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s5g
A M, Fung T, Kettenbach A, Chakrabarti R, Higgs H. A complex containing lysine-acetylated actin inhibits the formin INF2. Nat Cell Biol. 2019;21:592-602 pubmed publisher
  • western blot; mouse; 1:10,000; loading ...; fig s1
Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed publisher
  • western blot; human; loading ...; fig 3h
Tsai C, Tsai C, Yi J, Kao H, Huang Y, Wang C, et al. Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells. Sci Rep. 2019;9:5197 pubmed publisher
  • western blot; human; fig 1c
Patel N, Wang J, Shiozawa K, Jones K, Zhang Y, Prokop J, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. iScience. 2019;13:43-54 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 1c
Smith B, Wang S, Jaime Figueroa S, Harbin A, Wang J, Hamman B, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019;10:131 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 1a
Weinberg S, Singer B, Steinert E, Martinez C, Mehta M, Martínez Reyes I, et al. Mitochondrial complex III is essential for suppressive function of regulatory T cells. Nature. 2019;565:495-499 pubmed publisher
  • western blot; human; loading ...; fig 1a
Cui Y, Carosi J, Yang Z, Ariotti N, Kerr M, Parton R, et al. Retromer has a selective function in cargo sorting via endosome transport carriers. J Cell Biol. 2019;218:615-631 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 5b
Makhoul C, Gosavi P, Duffield R, Delbridge B, Williamson N, Gleeson P. Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Mol Biol Cell. 2019;30:370-386 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s1a
Arii J, Watanabe M, Maeda F, Tokai Nishizumi N, Chihara T, Miura M, et al. ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity. Nat Commun. 2018;9:3379 pubmed publisher
  • western blot; human; loading ...; fig 1h
Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, et al. VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science. 2018;361:290-295 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:500; fig 4d
Song P, Perkins B. Developmental expression of the zebrafish Arf-like small GTPase paralogs arl13a and arl13b. Gene Expr Patterns. 2018;29:82-87 pubmed publisher
  • western blot; mouse; loading ...
Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed publisher
  • western blot; human; loading ...; fig 1d
Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al. SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science. 2018;360:800-805 pubmed publisher
  • western blot; mouse; loading ...; fig 3d
Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 2c
Ruppert J, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash A, et al. HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry. EMBO J. 2018;37: pubmed publisher
  • western blot; human; 1:50,000; loading ...; fig s2f
Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 3a
Qu X, Yuan F, Corona C, Pasini S, Pero M, Gundersen G, et al. Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity. J Cell Biol. 2017;216:3161-3178 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 6a
Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, et al. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Sci Rep. 2017;7:1474 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s2d
Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s4f
Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard Levin Z, et al. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev. 2017;31:463-480 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig s5c
Bohnacker T, Prota A, Beaufils F, Burke J, Melone A, Inglis A, et al. Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun. 2017;8:14683 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig s16a
Martínez Martín N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, et al. A switch from canonical to noncanonical autophagy shapes B cell responses. Science. 2017;355:641-647 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7a
  • western blot; human; loading ...; fig 3b
Francis J, Newman L, Cunningham L, Kahn R. A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network. J Biol Chem. 2017;292:4336-4349 pubmed publisher
  • immunocytochemistry; Japanese rice fish; 1:100; loading ...; fig s10a
Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, et al. Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses. Nat Commun. 2017;8:14090 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s2i
Bendre S, Rondelet A, Hall C, Schmidt N, Lin Y, Brouhard G, et al. GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK. J Cell Biol. 2016;215:631-647 pubmed
  • immunocytochemistry; fruit fly ; 1:1000; loading ...; fig 3a
Qu Y, Hahn I, Webb S, Pearce S, Prokop A. Periodic actin structures in neuronal axons are required to maintain microtubules. Mol Biol Cell. 2017;28:296-308 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2a
Capalbo L, Mela I, Abad M, Jeyaprakash A, Edwardson J, D Avino P. Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis. Open Biol. 2016;6: pubmed
  • western blot; human; fig 3
  • western blot; mouse; fig 6
Nowacka J, Baumgartner C, Pelorosso C, Roth M, Zuber J, Baccarini M. MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 2016;7:80113-80130 pubmed publisher
  • western blot; human; fig 1
Andriani G, Almeida V, Faggioli F, Mauro M, Tsai W, Santambrogio L, et al. Whole Chromosome Instability induces senescence and promotes SASP. Sci Rep. 2016;6:35218 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 2c
Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  • western blot; human; loading ...; fig 5b
Koch K, Hartmann R, Schröter F, Suwala A, Maciaczyk D, Krüger A, et al. Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells. Oncotarget. 2016;7:73414-73431 pubmed publisher
  • immunocytochemistry; human; 1:500
Truong D, Puleo J, Llave A, Mouneimne G, Kamm R, Nikkhah M. Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment. Sci Rep. 2016;6:34094 pubmed publisher
  • proximity ligation assay; mouse; 1:20; fig 4
Frolikova M, Sebkova N, Ded L, Dvorakova Hortova K. Characterization of CD46 and ?1 integrin dynamics during sperm acrosome reaction. Sci Rep. 2016;6:33714 pubmed publisher
  • western blot; mouse; fig 1
Kotoku T, Kosaka K, Nishio M, Ishida Y, Kawaichi M, Matsuda E. CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells. Sci Rep. 2016;6:34188 pubmed publisher
  • western blot; human; 1:10,000; fig s8
Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed publisher
  • western blot; human; fig 3
Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  • western blot; human; 1:1000; fig 2c
Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed publisher
  • immunocytochemistry; fruit fly ; 1:2000; fig 5
  • western blot; fruit fly ; 1:5000; fig 4
Meghini F, Martins T, Tait X, Fujimitsu K, Yamano H, Glover D, et al. Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. Nat Commun. 2016;7:12607 pubmed publisher
  • western blot; human; 1:2500; fig 4
  • western blot; rat; 1:2500; fig s2
Perez C, Pérez Zúñiga F, Garrido F, Reytor E, Portillo F, Pajares M. The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases. PLoS ONE. 2016;11:e0161672 pubmed publisher
  • western blot; human; fig s1
Fokkelman M, Balcıoğlu H, Klip J, Yan K, Verbeek F, Danen E, et al. Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour. Sci Rep. 2016;6:31707 pubmed publisher
  • western blot; mouse; 1:5000; fig s2
Saatcioglu H, Cuevas I, Castrillon D. Control of Oocyte Reawakening by Kit. PLoS Genet. 2016;12:e1006215 pubmed publisher
  • western blot; mouse; fig 7
Furukawa Y, Tanemura K, Igarashi K, Ideta Otsuka M, Aisaki K, Kitajima S, et al. Learning and Memory Deficits in Male Adult Mice Treated with a Benzodiazepine Sleep-Inducing Drug during the Juvenile Period. Front Neurosci. 2016;10:339 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 1d
Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, et al. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun. 2016;7:12431 pubmed publisher
  • western blot; human; fig 5
Dhamad A, Zhou Z, Zhou J, Du Y. Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ER?) and Biochemical Characterization of the ER?-Hsp70 Interaction. PLoS ONE. 2016;11:e0160312 pubmed publisher
  • western blot; human; fig 3
Fritsch K, Mernberger M, Nist A, Stiewe T, Brehm A, Jacob R. Galectin-3 interacts with components of the nuclear ribonucleoprotein complex. BMC Cancer. 2016;16:502 pubmed publisher
  • immunocytochemistry; human; 1:5000; fig 4
  • western blot; human; 1:5000; fig 2
Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016;214:155-66 pubmed publisher
  • western blot; human; 1:1000; fig 4
Belvedere R, Bizzarro V, Forte G, Dal Piaz F, Parente L, Petrella A. Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway. Sci Rep. 2016;6:29660 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Miles D, de Vries N, Gisler S, Lieftink C, Akhtar W, Gogola E, et al. TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming. Stem Cells. 2017;35:147-157 pubmed publisher
  • western blot; mouse; 1:1000; fig 4g
Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann J, Manns M, et al. MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun. 2016;7:11916 pubmed publisher
  • western blot; human; fig s3
Bennesch M, Segala G, Wider D, Picard D. LSD1 engages a corepressor complex for the activation of the estrogen receptor ? by estrogen and cAMP. Nucleic Acids Res. 2016;44:8655-8670 pubmed
  • western blot; mouse; 1:5000; fig 3
  • western blot; African green monkey; 1:5000; fig 1
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
  • immunocytochemistry; mouse; 1:400; loading ...; fig 3c
Eymery A, Liu Z, Ozonov E, Stadler M, Peters A. The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos. Development. 2016;143:2767-79 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Yin Y, Gao D, Wang Y, Wang Z, Wang X, Ye J, et al. Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci U S A. 2016;113:E3773-81 pubmed publisher
  • western blot; human; 1:10,000; fig 3
Matsumura S, Kojidani T, Kamioka Y, Uchida S, Haraguchi T, Kimura A, et al. Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1. Nat Commun. 2016;7:ncomms11858 pubmed publisher
  • immunohistochemistry; fruit fly ; fig 3
Bergstralh D, Lovegrove H, Kujawiak I, Dawney N, Zhu J, Cooper S, et al. Pins is not required for spindle orientation in the Drosophila wing disc. Development. 2016;143:2573-81 pubmed publisher
  • western blot; rat; 1:1000; fig 1
Yin Y, Wang Y, Gao D, Ye J, Wang X, Fang L, et al. Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2. Sci Rep. 2016;6:27283 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 2
van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed publisher
  • western blot; human; fig 5a
Daubon T, Spuul P, Alonso F, Fremaux I, Genot E. VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells. J Cell Sci. 2016;129:2586-98 pubmed publisher
  • western blot; human; 1:5000; fig 6
  • western blot; mouse; 1:5000; fig s2
Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed publisher
  • western blot; mouse; 1:5000; fig 4
Kobayashi E, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat Commun. 2016;7:11624 pubmed publisher
  • western blot; bovine; 1:10,000; fig 2
Umezu K, Hiradate Y, Oikawa T, Ishiguro H, Numabe T, Hara K, et al. Exogenous neurotensin modulates sperm function in Japanese Black cattle. J Reprod Dev. 2016;62:409-14 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Kessler S, Laggai S, Van Wonterg E, Gemperlein K, Muller R, Haybaeck J, et al. Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. Front Physiol. 2016;7:147 pubmed publisher
  • western blot; human; fig 2
Guinot A, Oeztuerk Winder F, Ventura J. miR-17-92/p38? Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression. Cancer Res. 2016;76:4012-22 pubmed publisher
  • western blot; mouse; fig 6
de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
Chang C, Hsu W, Tsai J, Tang C, Tang T. CEP295 interacts with microtubules and is required for centriole elongation. J Cell Sci. 2016;129:2501-13 pubmed publisher
  • immunocytochemistry; human; 1:500; fig s1
Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed publisher
  • western blot; mouse; fig 5
Takenaka N, Nihata Y, Satoh T. Rac1 Activation Caused by Membrane Translocation of a Guanine Nucleotide Exchange Factor in Akt2-Mediated Insulin Signaling in Mouse Skeletal Muscle. PLoS ONE. 2016;11:e0155292 pubmed publisher
  • western blot; mouse; 1:5000; fig 4
Marei H, Carpy A, Macek B, Malliri A. Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors. Cell Cycle. 2016;15:1961-74 pubmed publisher
  • western blot; mouse; 1:2000; fig 1
Riaz M, Raz Y, van Putten M, Paniagua Soriano G, Krom Y, Florea B, et al. PABPN1-Dependent mRNA Processing Induces Muscle Wasting. PLoS Genet. 2016;12:e1006031 pubmed publisher
  • western blot; human; 1:5000; fig 6
Marthandan S, Baumgart M, Priebe S, Groth M, Schaer J, Kaether C, et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS ONE. 2016;11:e0154531 pubmed publisher
  • western blot; human; fig 3
Rapiteanu R, Davis L, Williamson J, Timms R, Paul Luzio J, Lehner P. A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin. Traffic. 2016;17:940-58 pubmed publisher
  • western blot; human; fig 6
Strappazzon F, Di Rita A, Cianfanelli V, D Orazio M, Nazio F, Fimia G, et al. Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis. Autophagy. 2016;12:963-75 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
  • western blot; human; 1:1000; fig 6
Lee K, Lee H, Lin H, Tsay H, Tsai F, Shyue S, et al. Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation. 2016;13:92 pubmed publisher
  • western blot; rat; 1:1000; fig 1
Mata Garrido J, Casafont I, Tapia O, Berciano M, Lafarga M. Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization. Acta Neuropathol Commun. 2016;4:41 pubmed publisher
  • immunohistochemistry; fruit fly ; 1:100; fig 1
Kwenda L, Collins C, Dattoli A, Dunleavy E. Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis. Development. 2016;143:1400-12 pubmed publisher
  • western blot; mouse; 1:5000; fig 1
Brüggen B, Kremser C, Bickert A, Ebel P, Vom Dorp K, Schultz K, et al. Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea. Eur J Neurosci. 2016;44:1700-13 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 2
Waisbourd Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, et al. The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17. Hepatology. 2016;64:880-93 pubmed publisher
  • western blot; human; fig 3
Chiang T, le Sage C, Larrieu D, Demir M, Jackson S. CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing. Sci Rep. 2016;6:24356 pubmed publisher
  • western blot; rat; tbl 3
Taguchi K, Takaku M, Egner P, Morita M, Kaneko T, Mashimo T, et al. Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity. Toxicol Sci. 2016;152:40-52 pubmed publisher
  • western blot; mouse; 1:5000; fig 1
Juárez Vicente F, Luna Pelaez N, Garcia Dominguez M. The Sumo protease Senp7 is required for proper neuronal differentiation. Biochim Biophys Acta. 2016;1863:1490-8 pubmed publisher
  • western blot; human; fig 4
Strickland S, Vande Pol S. The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC. J Virol. 2016;90:5611-5621 pubmed publisher
  • immunocytochemistry; human; fig 2
McKenzie C, Bassi Z, Debski J, Gottardo M, Callaini G, Dadlez M, et al. Cross-regulation between Aurora B and Citron kinase controls midbody architecture in cytokinesis. Open Biol. 2016;6: pubmed publisher
  • immunocytochemistry; human; fig 2
Zhao W, Liu J, Zhang X, Deng L. MLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1. J Cell Biol. 2016;212:829-43 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 3
  • western blot; human; 1:1000; fig 3
Chavali P, Chandrasekaran G, Barr A, Tátrai P, Taylor C, Papachristou E, et al. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun. 2016;7:11005 pubmed publisher
  • western blot; human; fig 5
Mitxelena J, Apraiz A, Vallejo Rodríguez J, Malumbres M, Zubiaga A. E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation. Nucleic Acids Res. 2016;: pubmed
  • immunocytochemistry; mouse; fig 2
Makani V, Jang Y, Christopher K, Judy W, Eckstein J, Hensley K, et al. BBB-Permeable, Neuroprotective, and Neurotrophic Polysaccharide, Midi-GAGR. PLoS ONE. 2016;11:e0149715 pubmed publisher
  • western blot; human; fig 4
Nakayama R, Zhang Y, Czaplinski J, Anatone A, Sicinska E, Fletcher J, et al. Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma. Oncotarget. 2016;7:16581-92 pubmed publisher
  • western blot; human; 1:5000; fig 1c
McLaughlin D, Coey C, Yang W, Drohat A, Matunis M. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo. J Biol Chem. 2016;291:9014-24 pubmed publisher
  • western blot; human; 1:20,000; fig 3g
Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K. Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun. 2016;7:10777 pubmed publisher
  • western blot; human; 1:1000
Jia L, Li B, Yu H. The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation. Nat Commun. 2016;7:10818 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Jackson S, Olufs Z, Tran K, Zaidan N, Sridharan R. Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage. Stem Cell Reports. 2016;6:302-11 pubmed publisher
  • western blot; mouse; 1:10,000; fig 3
del Río C, Navarrete C, Collado J, Bellido M, Gómez Cañas M, Pazos M, et al. The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways. Sci Rep. 2016;6:21703 pubmed publisher
  • western blot; human; fig 1
Baron A, von Schubert C, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. elife. 2016;5: pubmed publisher
  • western blot; mouse; fig 3c
Malecova B, Dall Agnese A, Madaro L, Gatto S, Coutinho Toto P, Albini S, et al. TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells. elife. 2016;5: pubmed publisher
  • immunocytochemistry; mouse; fig 3
  • western blot; mouse; 1:5000; fig 1
Liu A, Zhou Z, Dang R, Zhu Y, Qi J, He G, et al. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization. J Cell Biol. 2016;212:449-63 pubmed publisher
  • immunocytochemistry; human; fig 1
  • immunocytochemistry; roundworm ; fig 2
Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed publisher
  • western blot; rat; fig 1
Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher
  • western blot; mouse; 1:10,000; fig 1
Sharma A, Lyashchenko A, Lu L, Nasrabady S, Elmaleh M, Mendelsohn M, et al. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nat Commun. 2016;7:10465 pubmed publisher
  • western blot; human; fig 1
Dos Santos E, Carneiro Lobo T, Aoki M, Levantini E, Bassères D. Aurora kinase targeting in lung cancer reduces KRAS-induced transformation. Mol Cancer. 2016;15:12 pubmed publisher
  • western blot; human; 1:5000; fig 6
Swaminathan V, Fischer R, Waterman C. The FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin. Mol Biol Cell. 2016;27:1085-100 pubmed publisher
  • immunohistochemistry; roundworm ; 1:200; fig 3
  • western blot; roundworm ; 1:5000; fig 1
Franz A, Pirson P, Pilger D, Halder S, Achuthankutty D, Kashkar H, et al. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. Nat Commun. 2016;7:10612 pubmed publisher
  • immunocytochemistry; longfin inshore squid; fig 1
Stevenson J, Conaty E, Walsh R, Poidomani P, Samoriski C, Scollins B, et al. The Amyloid Precursor Protein of Alzheimer's Disease Clusters at the Organelle/Microtubule Interface on Organelles that Bind Microtubules in an ATP Dependent Manner. PLoS ONE. 2016;11:e0147808 pubmed publisher
  • western blot; human; 1:10,000; fig 1
Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed publisher
  • western blot; human; 1:10,000; fig 1a
Rasmussen R, Gajjar M, Jensen K, Hamerlik P. Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma. Mol Oncol. 2016;10:751-63 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 4
  • western blot; mouse; 1:1000; fig 4
Luchsinger L, de Almeida M, Corrigan D, Mumau M, Snoeck H. Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential. Nature. 2016;529:528-31 pubmed publisher
  • western blot; human; fig 1
Kelkar M, Senthilkumar K, Jadhav S, Gupta S, Ahn B, De A. Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation. Sci Rep. 2016;6:19341 pubmed publisher
  • immunocytochemistry; fruit fly ; fig 2
  • western blot; fruit fly ; 1:2000; fig 3
Mauvezin C, Neisch A, Ayala C, Kim J, Beltrame A, Braden C, et al. Coordination of autophagosome-lysosome fusion and transport by a Klp98A-Rab14 complex in Drosophila. J Cell Sci. 2016;129:971-82 pubmed publisher
  • immunocytochemistry; human; 1:250
  • western blot; human; 1:5000
Hori A, Barnouin K, Snijders A, Toda T. A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation. EMBO Rep. 2016;17:326-37 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Murakami K, Günesdogan U, Zylicz J, Tang W, Sengupta R, Kobayashi T, et al. NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers. Nature. 2016;529:403-407 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 7
Zhou H, Wang T, Zheng T, Teng J, Chen J. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun. 2016;7:10151 pubmed publisher
  • immunocytochemistry; long-nosed rat kangaroo; 1:500; loading ...; fig 1i
Kajtez J, Solomatina A, Novak M, Polak B, Vukušić K, Rüdiger J, et al. Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores. Nat Commun. 2016;7:10298 pubmed publisher
  • western blot; human; 1:5000; fig 2
Nelson J, Cook E, Loregger A, Hoeksema M, Scheij S, Kovacevic I, et al. Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake. J Biol Chem. 2016;291:4813-25 pubmed publisher
  • western blot; human; fig 1
Ge C, Che L, Du C. The UBC Domain Is Required for BRUCE to Promote BRIT1/MCPH1 Function in DSB Signaling and Repair Post Formation of BRUCE-USP8-BRIT1 Complex. PLoS ONE. 2015;10:e0144957 pubmed publisher
  • western blot; rat; 1:5000; fig s6
Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed publisher
  • western blot; mouse; fig 4
Giampietro C, Disanza A, Bravi L, Barrios Rodiles M, Corada M, Frittoli E, et al. The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling. J Cell Biol. 2015;211:1177-92 pubmed publisher
  • western blot; mouse; 1:2500
Franco Villanueva A, Wandosell F, Antón I. Neuritic complexity of hippocampal neurons depends on WIP-mediated mTORC1 and Abl family kinases activities. Brain Behav. 2015;5:e00359 pubmed publisher
  • immunocytochemistry; human; 1:1500; fig 1
  • western blot; human; 1:1500; fig 1
  • immunocytochemistry; mouse; 1:1500; fig 5
Mills K, Brocardo M, Henderson B. APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane. Mol Biol Cell. 2016;27:466-82 pubmed publisher
  • western blot; mouse; 1:5000
Müller Schiffmann A, Herring A, Abdel Hafiz L, Chepkova A, Schäble S, Wedel D, et al. Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity. Brain. 2016;139:509-25 pubmed publisher
  • western blot; human; fig 2
Dupont T, Yang S, Patel J, Hatzi K, Malik A, Tam W, et al. Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma. Oncotarget. 2016;7:3520-32 pubmed publisher
  • western blot; mouse; 1:10,000; fig 4b
Ageta Ishihara N, Yamazaki M, Konno K, Nakayama H, Abe M, Hashimoto K, et al. A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance. Nat Commun. 2015;6:10090 pubmed publisher
  • immunocytochemistry; human; fig 1
Ohashi A, Ohori M, Iwai K, Nambu T, Miyamoto M, Kawamoto T, et al. A Novel Time-Dependent CENP-E Inhibitor with Potent Antitumor Activity. PLoS ONE. 2015;10:e0144675 pubmed publisher
  • western blot; human; 1:30,000; fig 4
Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al. Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation. Mol Cell Biol. 2016;36:615-27 pubmed publisher
  • western blot; rat; fig 3
Garcia Manteiga J, Bonfiglio S, Folladori L, Malosio M, Lazarevic D, Stupka E, et al. REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation. Front Cell Neurosci. 2015;9:438 pubmed publisher
  • western blot; mouse; fig 2a
Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, et al. KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. EMBO Mol Med. 2016;8:6-24 pubmed publisher
  • western blot; human; fig 1
Ni Y, Tao L, Chen C, Song H, Li Z, Gao Y, et al. The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33. Int J Mol Sci. 2015;16:27956-66 pubmed publisher
  • western blot; mouse; fig 2
Gao X, Krokowski D, Guan B, Bederman I, Majumder M, Parisien M, et al. Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response. elife. 2015;4:e10067 pubmed publisher
  • western blot; human; fig 4
dos Santos N, Matias A, Higa G, Kihara A, Cerchiaro G. Copper Uptake in Mammary Epithelial Cells Activates Cyclins and Triggers Antioxidant Response. Oxid Med Cell Longev. 2015;2015:162876 pubmed publisher
  • immunohistochemistry - paraffin section; fruit fly ; 1:500; fig s5f
  • western blot; fruit fly ; 1:1000; fig s5a
Gogendeau D, Siudeja K, Gambarotto D, Pennetier C, Bardin A, Basto R. Aneuploidy causes premature differentiation of neural and intestinal stem cells. Nat Commun. 2015;6:8894 pubmed publisher
  • western blot; mouse; fig 1
Jahic A, Khundadze M, Jaenisch N, Schüle R, Klimpe S, Klebe S, et al. The spectrum of KIAA0196 variants, and characterization of a murine knockout: implications for the mutational mechanism in hereditary spastic paraplegia type SPG8. Orphanet J Rare Dis. 2015;10:147 pubmed publisher
  • western blot; mouse; fig 1a
Iarriccio L, Manguán García C, Pintado Berninches L, Mancheño J, Molina A, Perona R, et al. GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells. PLoS ONE. 2015;10:e0142980 pubmed publisher
  • western blot; chicken; 1:1000; fig 3
Furuta M, Hori T, Fukagawa T. Chromatin binding of RCC1 during mitosis is important for its nuclear localization in interphase. Mol Biol Cell. 2016;27:371-81 pubmed publisher
  • immunocytochemistry; mouse; fig 2
Fontinha D, Lopes F, Marques S, Alenquer M, Simas J. Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells. PLoS ONE. 2015;10:e0142540 pubmed publisher
  • western blot; rat
Stanojlović M, Guševac I, Grković I, Zlatković J, Mitrović N, Zarić M, et al. Effects of chronic cerebral hypoperfusion and low-dose progesterone treatment on apoptotic processes, expression and subcellular localization of key elements within Akt and Erk signaling pathways in rat hippocampus. Neuroscience. 2015;311:308-21 pubmed publisher
  • western blot; human; 1:1000; fig 4d
Jia D, Tan Y, Liu H, Ooi S, Li L, Wright K, et al. Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo. Oncotarget. 2016;7:771-85 pubmed publisher
  • proximity ligation assay; human; fig 7
Dumas A, Lê Bury G, Marie Anaïs F, Herit F, Mazzolini J, Guilbert T, et al. The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking. J Cell Biol. 2015;211:359-72 pubmed publisher
  • western blot; mouse; fig 4
Zampieri A, Champagne J, Auzemery B, Fuentes I, Maurel B, Bienvenu F. Hyper sensitive protein detection by Tandem-HTRF reveals Cyclin D1 dynamics in adult mouse. Sci Rep. 2015;5:15739 pubmed publisher
  • western blot; mouse; fig 2
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher
  • immunocytochemistry; fruit fly ; 1:50; fig s1
Radford S, Hoang T, Głuszek A, Ohkura H, McKim K. Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes. PLoS Genet. 2015;11:e1005605 pubmed publisher
  • western blot; mouse; 1:5000; fig 6
Yuzugullu H, Baitsch L, Von T, Steiner A, Tong H, Ni J, et al. A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis. Nat Commun. 2015;6:8501 pubmed publisher
  • western blot; human; fig 7b
Miles W, Lepesant J, Bourdeaux J, Texier M, Kerenyi M, Nakakido M, et al. The LSD1 Family of Histone Demethylases and the Pumilio Posttranscriptional Repressor Function in a Complex Regulatory Feedback Loop. Mol Cell Biol. 2015;35:4199-211 pubmed publisher
  • western blot; human; 1:2000; fig 4
Bagulho A, Vilas Boas F, Pena A, Peneda C, Santos F, Jerónimo A, et al. The extracellular matrix modulates H2O2 degradation and redox signaling in endothelial cells. Redox Biol. 2015;6:454-460 pubmed publisher
  • western blot; fruit fly ; 1:3000; fig 4
Hasanagic M, van Meel E, Luan S, Aurora R, Kornfeld S, Eissenberg J. The lysosomal enzyme receptor protein (LERP) is not essential, but is implicated in lysosomal function in Drosophila melanogaster. Biol Open. 2015;4:1316-25 pubmed publisher
  • western blot; fruit fly ; 1:10,000; fig 3a
Beck K, Ehmann N, Andlauer T, Ljaschenko D, Strecker K, Fischer M, et al. Loss of the Coffin-Lowry syndrome-associated gene RSK2 alters ERK activity, synaptic function and axonal transport in Drosophila motoneurons. Dis Model Mech. 2015;8:1389-400 pubmed publisher
  • western blot; mouse; 1:5000; fig 1
Nemazanyy I, Montagnac G, Russell R, Morzyglod L, Burnol A, Guan K, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283 pubmed publisher
  • western blot; human
Zhu L, Wang Z, Wang W, Wang C, Hua S, Su Z, et al. Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis. J Biol Chem. 2015;290:27053-66 pubmed publisher
  • western blot; human
Qiao Y, Lin S, Chen Y, Voon D, Zhu F, Chuang L, et al. RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer. Oncogene. 2016;35:2664-74 pubmed publisher
  • western blot; human; 1:1000; fig 1c
Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed publisher
  • immunocytochemistry; mouse; fig 3
Hu M, Wang Z, Teng Y, Jiang Z, Ma X, Hou N, et al. Loss of protein phosphatase 6 in oocytes causes failure of meiosis II exit and impaired female fertility. J Cell Sci. 2015;128:3769-80 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Plescher M, Teleman A, Demetriades C. TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1. Sci Rep. 2015;5:13828 pubmed publisher
  • western blot; human; 1:5000; fig 5
Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R, et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int. 2015;2015:731938 pubmed publisher
  • immunocytochemistry; human; 1:4000; fig s2
  • western blot; human; 1:10,000; fig s2
Van de Mark D, Kong D, Loncarek J, Stearns T. MDM1 is a microtubule-binding protein that negatively regulates centriole duplication. Mol Biol Cell. 2015;26:3788-802 pubmed publisher
  • western blot; human; fig 4
Bida O, Gidoni M, Ideses D, Efroni S, Ginsberg D. A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel. Oncotarget. 2015;6:27880-90 pubmed publisher
  • western blot; human; 1:4000; fig 1
Moreau K, Ghislat G, Hochfeld W, Renna M, Zavodszky E, Runwal G, et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun. 2015;6:8045 pubmed publisher
  • western blot; dogs; 1:10,000; fig 1a
Archibald A, Al Masri M, Liew Spilger A, McCaffrey L. Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling. Mol Biol Cell. 2015;26:3578-95 pubmed publisher
  • western blot; mouse; 1:2000
Meraviglia V, Azzimato V, Colussi C, Florio M, Binda A, Panariti A, et al. Acetylation mediates Cx43 reduction caused by electrical stimulation. J Mol Cell Cardiol. 2015;87:54-64 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 3
  • western blot; mouse; 1:5000; fig 4
Guo Y, Zheng Y. Lamins position the nuclear pores and centrosomes by modulating dynein. Mol Biol Cell. 2015;26:3379-89 pubmed publisher
  • western blot; human; fig 1c
Roncero A, López Nieva P, Cobos Fernández M, Villa Morales M, González Sánchez L, López Lorenzo J, et al. Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. Leukemia. 2016;30:94-103 pubmed publisher
  • western blot; human; 1:7500; fig 4
Kortüm F, Harms F, Hennighausen N, Rosenberger G. αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor. PLoS ONE. 2015;10:e0132737 pubmed publisher
  • western blot; human; 1:10,000; fig 1
Schraivogel D, Schindler S, Danner J, Kremmer E, Pfaff J, Hannus S, et al. Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Res. 2015;43:7447-61 pubmed publisher
  • western blot; human; fig 2
Felzen V, Hiebel C, Koziollek Drechsler I, Reißig S, Wolfrum U, Kögel D, et al. Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 2015;6:e1812 pubmed publisher
  • western blot; human; 1:1000; fig 3
Ohashi A, Ohori M, Iwai K, Nakayama Y, Nambu T, Morishita D, et al. Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells. Nat Commun. 2015;6:7668 pubmed publisher
  • immunoprecipitation; human; fig 3
  • immunocytochemistry; human; 1:200; fig 3
  • western blot; human; fig 3
Lin Y, Bhuwania R, Gromova K, Failla A, Lange T, Riecken K, et al. Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion. Oncotarget. 2015;6:18577-89 pubmed
  • immunohistochemistry; starlet sea anemone; 1:100; loading ...; fig 4a
Salinas Saavedra M, Stephenson T, Dunn C, Martindale M. Par system components are asymmetrically localized in ectodermal epithelia, but not during early development in the sea anemone Nematostella vectensis. Evodevo. 2015;6:20 pubmed publisher
  • immunocytochemistry; human; 1:2500; fig 7
  • western blot; human; 1:5000; fig 6
Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed publisher
  • western blot; human
Kim D, Yeom J, Lee B, Lee K, Bae J, Rhee S. Inhibition of discoidin domain receptor 2-mediated lung cancer cells progression by gold nanoparticle-aptamer-assisted delivery of peptides containing transmembrane-juxtamembrane 1/2 domain. Biochem Biophys Res Commun. 2015;464:392-5 pubmed publisher
  • western blot; rat; 1:5000; fig 2
Rato L, Alves M, Dias T, Cavaco J, Oliveira P. Testicular Metabolic Reprogramming in Neonatal Streptozotocin-Induced Type 2 Diabetic Rats Impairs Glycolytic Flux and Promotes Glycogen Synthesis. J Diabetes Res. 2015;2015:973142 pubmed publisher
  • western blot; mouse; 1:2500; fig 3
Selvaraj D, Gangadharan V, Michalski C, Kurejova M, Stösser S, Srivastava K, et al. A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain. Cancer Cell. 2015;27:780-96 pubmed publisher
  • western blot; human; 1:10,000; fig 4
Luo W, Liu W, Hu X, Hanna M, Caravaca A, Paul S. Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody. Sci Rep. 2015;5:11161 pubmed publisher
  • immunocytochemistry; human; 1:400; fig s1
  • western blot; human; 1:10,000; fig 4
Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infect Immun. 2015;83:3268-80 pubmed publisher
  • western blot; mouse
Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher
  • immunocytochemistry; human; 1:2500; fig 3
Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed publisher
  • western blot; human; fig 1d
Urban B, Collard T, Eagle C, Southern S, Greenhough A, Hamdollah Zadeh M, et al. BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling. Gut. 2016;65:1151-64 pubmed publisher
  • western blot; human; fig 4
Kim J, Kim B, Lee H, Thakkar S, Babbitt D, Eguchi S, et al. Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells. Am J Physiol Heart Circ Physiol. 2015;309:H425-33 pubmed publisher
  • immunocytochemistry; African green monkey; 1:250; loading ...; fig 3A
  • western blot; African green monkey; 1:1000; loading ...; fig 3B
Herms A, Bosch M, Reddy B, Schieber N, Fajardo A, Rupérez C, et al. AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation. Nat Commun. 2015;6:7176 pubmed publisher
  • western blot; human; fig 4
Alonso Curbelo D, Osterloh L, Cañón E, Calvo T, Martínez Herranz R, Karras P, et al. RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development. Oncotarget. 2015;6:11848-62 pubmed
  • immunocytochemistry; human; fig s4
  • western blot; human; fig s7
Panic M, Hata S, Neuner A, Schiebel E. The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes. PLoS Genet. 2015;11:e1005243 pubmed publisher
  • immunocytochemistry; dogs
  • western blot; dogs
Reales E, Bernabé Rubio M, Casares Arias J, Rentero C, Fernández Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed publisher
  • western blot; human; 1:1000
Tanas M, Ma S, Jadaan F, Ng C, Weigelt B, Reis Filho J, et al. Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein. Oncogene. 2016;35:929-38 pubmed publisher
  • western blot; human; fig 1
Moldovan J, Moran J. The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition. PLoS Genet. 2015;11:e1005121 pubmed publisher
  • western blot; Xenopus laevis; 1:20,000
Breznau E, Semack A, Higashi T, Miller A. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells. Mol Biol Cell. 2015;26:2439-55 pubmed publisher
  • western blot; mouse; fig 1
Thress K, Paweletz C, Felip E, Cho B, Stetson D, Dougherty B, et al. Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M. Nat Med. 2015;21:560-2 pubmed publisher
  • western blot; mouse; fig 3
Williamson R, Cowell C, Reville T, Roper J, Rendall T, Bass M. Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking. J Biol Chem. 2015;290:15437-49 pubmed publisher
  • western blot; mouse; 1:1000; fig s1
Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, et al. Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice. Nat Commun. 2015;6:7035 pubmed publisher
  • immunohistochemistry; California sea hare; 1:200
Carrigan I, Croll R, Wyeth R. Morphology, innervation, and peripheral sensory cells of the siphon of aplysia californica. J Comp Neurol. 2015;523:2409-25 pubmed publisher
  • western blot; mouse; 1:2000; fig 2
Vicuña L, Strochlic D, Latremoliere A, Bali K, Simonetti M, Husainie D, et al. The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med. 2015;21:518-23 pubmed publisher
  • western blot; human; fig 1
Gago Fuentes R, Fernández Puente P, Megias D, Carpintero Fernández P, Mateos J, Acea B, et al. Proteomic Analysis of Connexin 43 Reveals Novel Interactors Related to Osteoarthritis. Mol Cell Proteomics. 2015;14:1831-45 pubmed publisher
  • western blot; human; fig s7
Ceballos Chávez M, Subtil Rodríguez A, Giannopoulou E, Soronellas D, Vázquez Chávez E, Vicent G, et al. The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers. PLoS Genet. 2015;11:e1005174 pubmed publisher
  • western blot; human; 1:2500; fig s4e
Koizume S, Ito S, Nakamura Y, Yoshihara M, Furuya M, Yamada R, et al. Lipid starvation and hypoxia synergistically activate ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer. Mol Cancer. 2015;14:77 pubmed publisher
  • western blot; human
Tebbi A, Guittet O, Tuphile K, Cabrié A, Lepoivre M. Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis. J Biol Chem. 2015;290:14077-90 pubmed publisher
  • immunocytochemistry; human; 1:250
Hori A, Peddie C, Collinson L, Toda T. Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly. Mol Biol Cell. 2015;26:2005-19 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1b
Chen A, Akhshi T, Lavoie B, Wilde A. Importin β2 Mediates the Spatio-temporal Regulation of Anillin through a Noncanonical Nuclear Localization Signal. J Biol Chem. 2015;290:13500-9 pubmed publisher
  • western blot; mouse; 0.5 ug/ml; fig 1
  • western blot; human; 0.5 ug/ml; fig 1
Tabariès S, Annis M, Hsu B, Tam C, Savage P, Park M, et al. Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis. Oncotarget. 2015;6:9476-87 pubmed
  • western blot; mouse; 1.2 ug/ml
Dorgau B, Herrling R, Schultz K, Greb H, Segelken J, Ströh S, et al. Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions. J Comp Neurol. 2015;523:2062-81 pubmed publisher
  • western blot; mouse; 1:1000; fig 4a
Li L, Xu Z, Liu G, Xu C, Wang Z, Li X, et al. Expression of 1N3R-Tau isoform inhibits cell proliferation by inducing S phase arrest in N2a cells. PLoS ONE. 2015;10:e0119865 pubmed publisher
  • western blot; mouse; 1:5000
Shin C, Grossmann A, Holmen S, Robinson J. The BRAF kinase domain promotes the development of gliomas in vivo. Genes Cancer. 2015;6:9-18 pubmed
  • western blot; human
Ainsua Enrich E, Serrano Candelas E, Álvarez Errico D, Picado C, Sayós J, Rivera J, et al. The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival. J Immunol. 2015;194:4309-18 pubmed publisher
  • western blot; fruit fly ; fig s3
Takada S, Collins E, Kurahashi K. The FHA domain determines Drosophila Chk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses. Mol Biol Cell. 2015;26:1811-28 pubmed publisher
  • western blot; human
Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed publisher
  • western blot; human; fig 1
Kobayashi A, Hashizume C, Dowaki T, Wong R. Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A. Cell Cycle. 2015;14:1447-58 pubmed publisher
  • western blot; human; fig s24
Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed publisher
  • western blot; mouse; 1:2000; fig 5
Tassinari V, Campolo F, Cesarini V, Todaro F, Dolci S, Rossi P. Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand. Cell Death Dis. 2015;6:e1688 pubmed publisher
  • western blot; mouse; fig 1
Cheng H, Chern Y, Chen I, Liu C, Li S, Chun S, et al. Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown. PLoS Genet. 2015;11:e1005043 pubmed publisher
  • western blot; human; fig 1
Wengrod J, Wang D, Weiss S, Zhong H, Osman I, Gardner L. Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Sci Signal. 2015;8:ra27 pubmed publisher
  • western blot; mouse; fig 3
Gillespie M, Gold E, Ramsey S, Podolsky I, Aderem A, Ranish J. An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux. EMBO J. 2015;34:1244-58 pubmed publisher
  • western blot; human; 1:1000
Tsuru A, Setoguchi T, Matsunoshita Y, Nagao Kitamoto H, Nagano S, Yokouchi M, et al. Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression. Br J Cancer. 2015;112:1232-40 pubmed publisher
  • western blot; human; fig 2
Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, et al. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci. 2015;18:501-10 pubmed publisher
  • chromatin immunoprecipitation; human; 1:10,000
Carvallo L, Lopez L, Che F, Lim J, Eugenin E, Williams D, et al. Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes. J Immunol. 2015;194:3246-58 pubmed publisher
  • western blot; human
Banks C, Boanca G, Lee Z, Florens L, Washburn M. Proteins interacting with cloning scars: a source of false positive protein-protein interactions. Sci Rep. 2015;5:8530 pubmed publisher
  • western blot; mouse; 1:1000; fig 6,7
Beaven R, Dzhindzhev N, Qu Y, Hahn I, Dajas Bailador F, Ohkura H, et al. Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system. Mol Biol Cell. 2015;26:1491-508 pubmed publisher
  • western blot; human
Ito T, Taniguchi H, Fukagai K, Okamuro S, Kobayashi A. Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis. PLoS ONE. 2015;10:e0118336 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:750; fig 5
  • immunocytochemistry; human; 1:1000; fig 1
Morris E, Assi K, Salh B, Dedhar S. Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum. Sci Rep. 2015;5:8389 pubmed publisher
  • western blot; human; 1:1000; fig 5
Kondapalli K, Llongueras J, Capilla González V, Prasad H, Hack A, Smith C, et al. A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastoma. Nat Commun. 2015;6:6289 pubmed publisher
  • western blot; mouse; 1:2000
Chen J, Ren J, Jing Q, Lu S, Zhang Y, Liu Y, et al. TSH/TSHR Signaling Suppresses Fatty Acid Synthase (FASN) Expression in Adipocytes. J Cell Physiol. 2015;230:2233-9 pubmed publisher
  • immunohistochemistry; fruit fly ; 1:2000
Okumura M, Sakuma C, Miura M, Chihara T. Linking cell surface receptors to microtubules: tubulin folding cofactor D mediates Dscam functions during neuronal morphogenesis. J Neurosci. 2015;35:1979-90 pubmed publisher
  • western blot; zebrafish ; 1:2000; fig 4
Horstick E, Jordan D, Bergeron S, Tabor K, Serpe M, Feldman B, et al. Increased functional protein expression using nucleotide sequence features enriched in highly expressed genes in zebrafish. Nucleic Acids Res. 2015;43:e48 pubmed publisher
  • western blot; human; fig 1
Santhana Kumar K, Tripolitsioti D, Ma M, Grählert J, Egli K, Fiaschetti G, et al. The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma. Springerplus. 2015;4:19 pubmed publisher
  • western blot; bovine; fig s4
Marsolier J, Perichon M, Debarry J, Villoutreix B, Chluba J, Lopez T, et al. Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation. Nature. 2015;520:378-82 pubmed publisher
  • western blot; human; 1:2000
López de Figueroa P, Lotz M, Blanco F, Caramés B. Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes. Arthritis Rheumatol. 2015;67:966-76 pubmed publisher
  • western blot; human; fig 8
Thomas Y, Peter M, Mechali F, Blanchard J, Coux O, Baldin V. Kizuna is a novel mitotic substrate for CDC25B phosphatase. Cell Cycle. 2014;13:3867-77 pubmed publisher
  • western blot; human; fig s2
Brandstaetter H, Kishi Itakura C, Tumbarello D, Manstein D, Buss F. Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy. 2014;10:2310-23 pubmed publisher
  • immunocytochemistry; mouse; 1:1000
  • western blot; mouse; 1:5000
Kim J, Ishiguro K, Nambu A, Akiyoshi B, Yokobayashi S, Kagami A, et al. Meikin is a conserved regulator of meiosis-I-specific kinetochore function. Nature. 2015;517:466-71 pubmed publisher
  • immunoprecipitation; mouse; 1:2000-1:4000; fig 5
Imajo M, Ebisuya M, Nishida E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat Cell Biol. 2015;17:7-19 pubmed publisher
  • western blot; human
Ling X, Xu C, Fan C, Zhong K, Li F, Wang X. FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX. Cancer Res. 2014;74:7487-97 pubmed publisher
  • western blot; mouse; 1:5000; fig 6
Qiao X, Roth I, Féraille E, Hasler U. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle. 2014;13:3059-75 pubmed publisher
  • western blot; human
Li M, Bian C, Yu X. Poly(ADP-ribosyl)ation is recognized by ECT2 during mitosis. Cell Cycle. 2014;13:2944-51 pubmed publisher
  • immunocytochemistry; mouse
Hoon J, Li H, Koh C. POPX2 phosphatase regulates cell polarity and centrosome placement. Cell Cycle. 2014;13:2459-68 pubmed publisher
  • western blot; mouse; 1:20,000; fig 1
Meng L, Ward A, Chun S, Bennett C, Beaudet A, Rigo F. Towards a therapy for Angelman syndrome by targeting a long non-coding RNA. Nature. 2015;518:409-12 pubmed publisher
  • western blot; human; fig 2
Pickholtz I, Saadyan S, Keshet G, Wang V, Cohen R, Bouwman P, et al. Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells. Oncotarget. 2014;5:11827-46 pubmed
  • immunocytochemistry; rat; 1:250; fig 1
  • western blot; rat; 1:1000; fig 1
Leyk J, Goldbaum O, Noack M, Richter Landsberg C. Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance. J Mol Neurosci. 2015;55:1031-46 pubmed publisher
  • western blot; mouse
Green C, Fraser S, Day M. Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro. Hum Reprod. 2015;30:284-98 pubmed publisher
  • western blot; human; 1:10,000
Boscia F, Passaro C, Gigantino V, Perdonà S, Franco R, Portella G, et al. High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness. J Cell Physiol. 2015;230:1290-7 pubmed publisher
  • western blot; mouse; 1:10,000
Kararigas G, Fliegner D, Forler S, Klein O, Schubert C, Gustafsson J, et al. Comparative proteomic analysis reveals sex and estrogen receptor β effects in the pressure overloaded heart. J Proteome Res. 2014;13:5829-36 pubmed publisher
  • western blot; fruit fly ; fig 1
Andlauer T, Scholz Kornehl S, Tian R, Kirchner M, Babikir H, Depner H, et al. Drep-2 is a novel synaptic protein important for learning and memory. elife. 2014;3: pubmed publisher
  • western blot; human; 1:5000; fig 5
Husedzinovic A, Neumann B, Reymann J, Draeger Meurer S, Chari A, Erfle H, et al. The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization. Mol Biol Cell. 2015;26:161-71 pubmed publisher
  • western blot; African green monkey; fig 4
Korobko E, Kiselev S, Korobko I. Characterization of Rabaptin-5 γ isoform. Biochemistry (Mosc). 2014;79:856-64 pubmed publisher
  • western blot; mouse; 1:2500
Martínez Vega R, Garrido F, Partearroyo T, Cediel R, Zeisel S, Martínez Álvarez C, et al. Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism. FASEB J. 2015;29:418-32 pubmed publisher
  • western blot; mouse; 1:5000; fig 3
Katz Y, Li F, Lambert N, Sokol E, Tam W, Cheng A, et al. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. elife. 2014;3:e03915 pubmed publisher
  • western blot; mouse; 1:5000
Israeli Rosenberg S, Chen C, Li R, Deussen D, Niesman I, Okada H, et al. Caveolin modulates integrin function and mechanical activation in the cardiomyocyte. FASEB J. 2015;29:374-84 pubmed publisher
  • immunocytochemistry; Hydractinia echinata; 1:1000
Kraus Y, Flici H, Hensel K, Plickert G, Leitz T, Frank U. The embryonic development of the cnidarian Hydractinia echinata. Evol Dev. 2014;16:323-38 pubmed publisher
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 5
Mardilovich K, Gabrielsen M, McGarry L, Orange C, Patel R, Shanks E, et al. Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Mol Cancer Ther. 2015;14:246-58 pubmed publisher
  • western blot; human; fig 3
Bultema J, Boyle J, Malenke P, Martin F, Dell Angelica E, Cheney R, et al. Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomes. J Biol Chem. 2014;289:33513-28 pubmed publisher
  • immunocytochemistry; human; 1:1000
  • western blot; human; 1:1000
Agircan F, Schiebel E. Sensors at centrosomes reveal determinants of local separase activity. PLoS Genet. 2014;10:e1004672 pubmed publisher
  • immunohistochemistry; Rhynchospora tenuis; 1:40; fig s2
  • immunohistochemistry; Rhynchospora pubera
Cabral G, Marques A, Schubert V, Pedrosa Harand A, Schlögelhofer P. Chiasmatic and achiasmatic inverted meiosis of plants with holocentric chromosomes. Nat Commun. 2014;5:5070 pubmed publisher
  • western blot; human; fig 4
Reese J, Suman V, Subramaniam M, Wu X, Negron V, Gingery A, et al. ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer. BMC Cancer. 2014;14:749 pubmed publisher
  • western blot; human; 1:1000; fig 2
Ilagan J, Ramakrishnan A, Hayes B, Murphy M, Zebari A, Bradley P, et al. U2AF1 mutations alter splice site recognition in hematological malignancies. Genome Res. 2015;25:14-26 pubmed publisher
  • western blot; human
Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, et al. β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer. Cell Death Differ. 2015;22:298-310 pubmed publisher
  • immunocytochemistry; human; 1:5000; fig 1
  • western blot; human; 1:5000; fig 3
Chan Y, West S. Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nat Commun. 2014;5:4844 pubmed publisher
  • western blot; human; 1:2000
Ribeiro Varandas E, Pereira H, Monteiro S, Neves E, Brito L, Ferreira R, et al. Bisphenol A disrupts transcription and decreases viability in aging vascular endothelial cells. Int J Mol Sci. 2014;15:15791-805 pubmed publisher
  • western blot; rat; 1:2500
Rocha C, Martins A, Rato L, Silva B, Oliveira P, Alves M. Melatonin alters the glycolytic profile of Sertoli cells: implications for male fertility. Mol Hum Reprod. 2014;20:1067-76 pubmed publisher
  • immunoprecipitation; human; fig 3
Tao L, Chen C, Song H, Piccioni M, Shi G, Li B. Deubiquitination and stabilization of IL-33 by USP21. Int J Clin Exp Pathol. 2014;7:4930-7 pubmed
  • western blot; human
Liu J, Zheng L, Ma L, Wang B, Zhao Y, Wu N, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014;25:1154-1160 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 5
Rotunno M, Auclair J, Maniatis S, Shaffer S, AGAR J, Bosco D. Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis. J Biol Chem. 2014;289:28527-38 pubmed publisher
  • western blot; human
Peng M, Emmadi R, Wang Z, Wiley E, Gann P, Khan S, et al. PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors. Oncotarget. 2014;5:6038-48 pubmed
  • western blot; human
Ishii H, Saitoh M, Sakamoto K, Kondo T, Katoh R, Tanaka S, et al. Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms. J Biol Chem. 2014;289:27386-99 pubmed publisher
  • western blot; human; 1:5000
Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, et al. PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma. Mol Oncol. 2015;9:78-92 pubmed publisher
  • western blot; mouse; 1:10,000; fig 2
  • western blot; human; 1:10,000; fig 1
Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed publisher
  • western blot; Aspergillus sp.; 1:1000
James S, Banta T, Barra J, Ciraku L, Coile C, Cuda Z, et al. Restraint of the G2/M transition by the SR/RRM family mRNA shuttling binding protein SNXAHRB1 in Aspergillus nidulans. Genetics. 2014;198:617-33 pubmed publisher
  • western blot; mouse; 1:10,000; fig 5
Lee Y, Santé J, Comerci C, Cyge B, Menezes L, Li F, et al. Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function. Mol Biol Cell. 2014;25:2919-33 pubmed publisher
  • western blot; human
Isogaya K, Koinuma D, Tsutsumi S, Saito R, Miyazawa K, Aburatani H, et al. A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression. Cell Res. 2014;24:994-1008 pubmed publisher
  • western blot; human; fig s1
Smith C, Matheson T, Trombly D, Sun X, Campeau E, Han X, et al. A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli. Mol Biol Cell. 2014;25:2866-81 pubmed publisher
  • western blot; fruit fly ; 1:5000; fig s1
Galletta B, Guillen R, Fagerstrom C, Brownlee C, Lerit D, Megraw T, et al. Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies. Mol Biol Cell. 2014;25:2682-94 pubmed publisher
  • western blot; human; fig 3
Nickerson K, Homer C, Kessler S, Dixon L, Kabi A, Gordon I, et al. The dietary polysaccharide maltodextrin promotes Salmonella survival and mucosal colonization in mice. PLoS ONE. 2014;9:e101789 pubmed publisher
  • western blot; mouse; 1:5000
Lodato S, Molyneaux B, Zuccaro E, Goff L, Chen H, Yuan W, et al. Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014;17:1046-54 pubmed publisher
  • western blot; mouse; 1:10,000; fig 4
Hopkins J, Hwang G, Jacob J, Sapp N, Bedigian R, Oka K, et al. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet. 2014;10:e1004413 pubmed publisher
  • western blot; human; fig s4
Manguan García C, Pintado Berninches L, Carrillo J, Machado Pinilla R, Sastre L, Perez Quilis C, et al. Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells. PLoS ONE. 2014;9:e101424 pubmed publisher
  • western blot; mouse; fig 1
Takeda A, Oberoi Khanuja T, Glatz G, Schulenburg K, Scholz R, Carpy A, et al. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1. EMBO J. 2014;33:1784-801 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
O Rourke B, Gomez Ferreria M, Berk R, Hackl A, Nicholas M, O Rourke S, et al. Cep192 controls the balance of centrosome and non-centrosomal microtubules during interphase. PLoS ONE. 2014;9:e101001 pubmed publisher
  • western blot; human
Kim D, Birendra K, Zhu W, Motamedchaboki K, Doye V, Roux K. Probing nuclear pore complex architecture with proximity-dependent biotinylation. Proc Natl Acad Sci U S A. 2014;111:E2453-61 pubmed publisher
  • western blot; mouse
Soares F, Tattoli I, Rahman M, Robertson S, Belcheva A, Liu D, et al. The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. J Biol Chem. 2014;289:19317-30 pubmed publisher
  • western blot; pigs ; 1:10,000
  • immunocytochemistry; African green monkey; 1:10,000
Kielar M, Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci. 2014;17:923-33 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500
Li R, Tan J, Chen L, Feng J, Liang W, Guo X, et al. Iqcg is essential for sperm flagellum formation in mice. PLoS ONE. 2014;9:e98053 pubmed publisher
  • immunocytochemistry; African green monkey
Cheong F, Feng L, Sarkeshik A, Yates J, Schroer T. Dynactin integrity depends upon direct binding of dynamitin to Arp1. Mol Biol Cell. 2014;25:2171-80 pubmed publisher
  • western blot; human
  • western blot; mouse
Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
  • western blot; human; 1:15,000
Zavodszky E, Seaman M, Moreau K, Jimenez Sanchez M, Breusegem S, Harbour M, et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun. 2014;5:3828 pubmed publisher
  • western blot; human
Shaw Hallgren G, Chmielarska Masoumi K, Zarrizi R, Hellman U, Karlsson P, Helou K, et al. Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells. PLoS ONE. 2014;9:e96506 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 2
  • western blot; human; 1:10,000; fig 2
Thoresen S, Campsteijn C, Vietri M, Schink K, Liestøl K, Andersen J, et al. ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4. Nat Cell Biol. 2014;16:550-60 pubmed publisher
  • western blot; human
Garimella S, Gehlhaus K, Dine J, Pitt J, Grandin M, Chakka S, et al. Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening. Breast Cancer Res. 2014;16:R41 pubmed publisher
  • western blot; human
Hayes S, Hng K, Clark P, Thistlethwaite F, Hawkins R, Ang Y. Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens. World J Gastroenterol. 2014;20:4011-6 pubmed publisher
  • western blot; human
Touat Hamici Z, Legrain Y, Bulteau A, Chavatte L. Selective up-regulation of human selenoproteins in response to oxidative stress. J Biol Chem. 2014;289:14750-61 pubmed publisher
  • western blot; rat
Han X, Cheng D, Song F, Zeng T, An L, Xie K. Decelerated transport and its mechanism of 2,5-hexanedione on middle-molecular-weight neurofilament in rat dorsal root ganglia cells. Neuroscience. 2014;269:192-8 pubmed publisher
  • western blot; mouse; 1:1000
Feuer S, Liu X, Donjacour A, Lin W, Simbulan R, Giritharan G, et al. Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis. Endocrinology. 2014;155:1956-69 pubmed publisher
  • immunocytochemistry; human; 1:200
  • western blot; human
Kuo P, Huang Y, Hsieh C, Lee J, Lin B, Hung L. STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells. PLoS ONE. 2014;9:e93303 pubmed publisher
  • western blot; human; 1:1000
Rennoll S, Scott S, Yochum G. Targeted repression of AXIN2 and MYC gene expression using designer TALEs. Biochem Biophys Res Commun. 2014;446:1120-5 pubmed publisher
  • immunocytochemistry; human
Gunkel M, Flottmann B, Heilemann M, Reymann J, Erfle H. Integrated and correlative high-throughput and super-resolution microscopy. Histochem Cell Biol. 2014;141:597-603 pubmed publisher
  • western blot; pigs
  • western blot; human
Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed publisher
  • western blot; human
Herve D, Philippi A, Belbouab R, Zerah M, Chabrier S, Collardeau Frachon S, et al. Loss of ?1?1 soluble guanylate cyclase, the major nitric oxide receptor, leads to moyamoya and achalasia. Am J Hum Genet. 2014;94:385-94 pubmed publisher
  • western blot; mouse; 1:1000
Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, et al. Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation. J Biol Chem. 2014;289:9865-79 pubmed publisher
  • western blot; human
Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed publisher
  • western blot; rat
Ryszawy D, Sarna M, Rak M, Szpak K, Kedracka Krok S, Michalik M, et al. Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer. Carcinogenesis. 2014;35:1920-30 pubmed publisher
  • western blot; mouse
Wong Y, Holzbaur E. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci. 2014;34:1293-305 pubmed publisher
  • western blot; mouse
Xu C, Fan C, Wang X. Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase. Oncogene. 2015;34:281-9 pubmed publisher
  • western blot; rat; 1:5000
Sike A, Nagy E, Vedelek B, Pusztai D, Szerémy P, Venetianer A, et al. mRNA levels of related Abcb genes change opposite to each other upon histone deacetylase inhibition in drug-resistant rat hepatoma cells. PLoS ONE. 2014;9:e84915 pubmed publisher
  • western blot; roundworm ; fig 6.5
Manil Ségalen M, Culetto E, Legouis R, Lefebvre C. Interactions between endosomal maturation and autophagy: analysis of ESCRT machinery during Caenorhabditis elegans development. Methods Enzymol. 2014;534:93-118 pubmed publisher
  • immunocytochemistry; human
Klinger M, Wang W, Kuhns S, Bärenz F, Dräger Meurer S, Pereira G, et al. The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone. Mol Biol Cell. 2014;25:495-507 pubmed publisher
  • western blot; human
Sharma Walia N, Chandran K, Patel K, Veettil M, Marginean A. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol. 2014;88:2131-56 pubmed publisher
  • western blot; mouse
Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, et al. HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. PLoS Biol. 2013;11:e1001717 pubmed publisher
  • western blot; human; 1:1000
Rennoll S, Konsavage W, Yochum G. Nuclear AXIN2 represses MYC gene expression. Biochem Biophys Res Commun. 2014;443:217-22 pubmed publisher
  • western blot; mouse; fig 6
Tan S, Shui G, Zhou J, Shi Y, Huang J, Xia D, et al. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. Autophagy. 2014;10:226-42 pubmed publisher
  • western blot; rat; 1:5000
Alves M, Martins A, Vaz C, Correia S, Moreira P, Oliveira P, et al. Metformin and male reproduction: effects on Sertoli cell metabolism. Br J Pharmacol. 2014;171:1033-42 pubmed publisher
  • western blot; human; fig 3
Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods Mol Biol. 2014;1087:103-14 pubmed publisher
  • western blot; mouse; 1:10 000
Garcia E, Santana Martínez R, Silva Islas C, Colín González A, Galvan Arzate S, Heras Y, et al. S-allyl cysteine protects against MPTP-induced striatal and nigral oxidative neurotoxicity in mice: participation of Nrf2. Free Radic Res. 2014;48:159-67 pubmed publisher
  • western blot; human
Aukkarasongsup P, Haruyama N, Matsumoto T, Shiga M, Moriyama K. Periostin inhibits hypoxia-induced apoptosis in human periodontal ligament cells via TGF-? signaling. Biochem Biophys Res Commun. 2013;441:126-32 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed publisher
  • immunocytochemistry; human
Hashizume C, Moyori A, Kobayashi A, Yamakoshi N, Endo A, Wong R. Nucleoporin Nup62 maintains centrosome homeostasis. Cell Cycle. 2013;12:3804-16 pubmed publisher
  • western blot; human; fig 5
Martinez Sanchez A, Murphy C. miR-1247 functions by targeting cartilage transcription factor SOX9. J Biol Chem. 2013;288:30802-14 pubmed publisher
  • western blot; mouse; 1:5000
Kim Y, Zheng Y. Generation and characterization of a conditional deletion allele for Lmna in mice. Biochem Biophys Res Commun. 2013;440:8-13 pubmed publisher
  • western blot; human; 1:5000
Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed publisher
  • western blot; mouse
Horton J, Stefanick D, Gassman N, Williams J, Gabel S, Cuneo M, et al. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. DNA Repair (Amst). 2013;12:774-85 pubmed publisher
  • western blot; mouse; 1:10,000
Yuki K, Yoshida T, Miyake S, Tsubota K, Ozawa Y. Neuroprotective role of superoxide dismutase 1 in retinal ganglion cells and inner nuclear layer cells against N-methyl-d-aspartate-induced cytotoxicity. Exp Eye Res. 2013;115:230-8 pubmed publisher
  • western blot; human; fig 1a
Alfonso Pérez T, Domínguez Sánchez M, Garcia Dominguez M, Reyes J. Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis. Oncogene. 2014;33:3064-74 pubmed publisher
  • western blot; mouse
Walser R, Burke J, Gogvadze E, Bohnacker T, Zhang X, Hess D, et al. PKC? phosphorylates PI3K? to activate it and release it from GPCR control. PLoS Biol. 2013;11:e1001587 pubmed publisher
  • western blot; mouse; 1:500
Zhang L, Wahlin K, Li Y, Masuda T, Yang Z, Zack D, et al. RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. Mol Vis. 2013;19:1371-86 pubmed
  • western blot; mouse
Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature. 2013;498:492-6 pubmed publisher
  • immunocytochemistry; Xenopus laevis; 1:100
  • western blot; Xenopus laevis; 1 ug/ml
Samwer M, Dehne H, Spira F, Kollmar M, Gerlich D, Urlaub H, et al. The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J. 2013;32:1886-902 pubmed publisher
  • western blot; mouse
  • western blot; human
Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed publisher
  • western blot; mouse; 1:5000; fig s4
Grabole N, Tischler J, Hackett J, Kim S, Tang F, Leitch H, et al. Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation. EMBO Rep. 2013;14:629-37 pubmed publisher
  • western blot; human; fig 3
Moreno A, Soleto I, García Sanz P, Moreno Bueno G, Palmero I. ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth. Oncogene. 2014;33:1945-53 pubmed publisher
  • western blot; mouse; fig s11
Reginensi A, Scott R, Gregorieff A, Bagherie Lachidan M, Chung C, Lim D, et al. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. PLoS Genet. 2013;9:e1003380 pubmed publisher
  • immunocytochemistry; mouse
Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, et al. NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells. 2013;31:1278-86 pubmed publisher
  • immunohistochemistry; Xenopus laevis; 1:1000
Dush M, Nascone Yoder N. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development. 2013;140:1457-66 pubmed publisher
  • immunocytochemistry; mouse
Trakala M, Fernández Miranda G, Perez de Castro I, Heeschen C, Malumbres M. Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1). Cell Cycle. 2013;12:1030-41 pubmed publisher
  • western blot; rat; 1:1000
Peng X, Gao H, Wang Y, Yang B, Liu T, Sun Y, et al. Conversion of rat embryonic stem cells into neural precursors in chemical-defined medium. Biochem Biophys Res Commun. 2013;431:783-7 pubmed publisher
  • immunocytochemistry; human
Gu B, Eick D, Bensaude O. CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res. 2013;41:1591-603 pubmed publisher
  • western blot; human
Tattoli I, Philpott D, Girardin S. The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole. Biol Open. 2012;1:1215-25 pubmed publisher
  • western blot; human
Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed publisher
  • western blot; human
Fan C, Lum M, Xu C, Black J, Wang X. Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response. J Biol Chem. 2013;288:1674-84 pubmed publisher
  • western blot; human
Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed publisher
  • immunocytochemistry; human; 1:1000
Gao M, Rendtlew Danielsen J, Wei L, Zhou D, Xu Q, Li M, et al. A novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrity. PLoS ONE. 2012;7:e49687 pubmed publisher
  • immunocytochemistry; human; 1:200
  • western blot; human; 1:2000
Ribeiro Varandas E, Viegas W, Sofia Pereira H, Delgado M. Bisphenol A at concentrations found in human serum induces aneugenic effects in endothelial cells. Mutat Res. 2013;751:27-33 pubmed publisher
  • immunocytochemistry; human; 1:3000
Aivar P, Fernandez Orth J, Gomis Pèrez C, Alberdi A, Alaimo A, Rodriguez M, et al. Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker. PLoS ONE. 2012;7:e47263 pubmed publisher
  • immunocytochemistry; human; 1:500
Dinh P, Beura L, Das P, Panda D, Das A, Pattnaik A. Induction of stress granule-like structures in vesicular stomatitis virus-infected cells. J Virol. 2013;87:372-83 pubmed publisher
  • western blot; human
Coffey K, Blackburn T, Cook S, Golding B, Griffin R, Hardcastle I, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS ONE. 2012;7:e45539 pubmed publisher
  • immunocytochemistry; human
Pakala S, Nair V, Reddy S, Kumar R. Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localization. J Biol Chem. 2012;287:40560-9 pubmed publisher
  • immunohistochemistry; red rock crab; 1:1000
Hebras C, McDougall A. Urochordate ascidians possess a single isoform of Aurora kinase that localizes to the midbody via TPX2 in eggs and cleavage stage embryos. PLoS ONE. 2012;7:e45431 pubmed publisher
  • western blot; mouse; 1:10,000
Wallmen B, Schrempp M, Hecht A. Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/?-catenin target gene expression. Nucleic Acids Res. 2012;40:9455-69 pubmed publisher
  • immunocytochemistry; human
Ma M, Chircop M. SNX9, SNX18 and SNX33 are required for progression through and completion of mitosis. J Cell Sci. 2012;125:4372-82 pubmed publisher
  • western blot; human
Liu K, Wang H, Long Y, Ye J, Yuan L. Coordinate lentiviral expression of Cre recombinase and RFP/EGFP mediated by FMDV 2A and analysis of Cre activity. J Cell Biochem. 2012;113:2909-19 pubmed publisher
  • western blot; human
Shia W, Okumura A, Yan M, Sarkeshik A, Lo M, Matsuura S, et al. PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential. Blood. 2012;119:4953-62 pubmed publisher
  • immunocytochemistry; roundworm ; 1:500
Mikeladze Dvali T, von Tobel L, Strnad P, Knott G, Leonhardt H, Schermelleh L, et al. Analysis of centriole elimination during C. elegans oogenesis. Development. 2012;139:1670-9 pubmed publisher
  • western blot; mouse
Austenaa L, Barozzi I, Chronowska A, Termanini A, Ostuni R, Prosperini E, et al. The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesis. Immunity. 2012;36:572-85 pubmed publisher
  • western blot; fruit fly ; 1:2,000
Herz H, Mohan M, Garrett A, Miller C, Casto D, Zhang Y, et al. Polycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila. Mol Cell Biol. 2012;32:1683-93 pubmed publisher
  • immunohistochemistry; rye; 1:100
Houben A, Kumke K, Nagaki K, Hause G. CENH3 distribution and differential chromatin modifications during pollen development in rye (Secale cereale L.). Chromosome Res. 2011;19:471-80 pubmed publisher
  • western blot; mouse; 1:5000
Clarke J, Emson P, Irvine R. Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain. J Comp Neurol. 2009;517:296-312 pubmed publisher
  • immunohistochemistry - paraffin section; marine lamprey
Jin L, Zhang G, Jamison C, Takano H, Haydon P, Selzer M. Axon regeneration in the absence of growth cones: acceleration by cyclic AMP. J Comp Neurol. 2009;515:295-312 pubmed publisher
  • western blot; human
Ramsey C, Yeung F, Stoddard P, Li D, Creutz C, Mayo M. Copine-I represses NF-kappaB transcription by endoproteolysis of p65. Oncogene. 2008;27:3516-26 pubmed publisher
  • western blot; human
Young D, Jonnalagadda J, Gatei M, Jans D, Meyn S, Khanna K. Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association. J Biol Chem. 2005;280:27587-94 pubmed
  • western blot; human
Madison D, Yaciuk P, Kwok R, Lundblad J. Acetylation of the adenovirus-transforming protein E1A determines nuclear localization by disrupting association with importin-alpha. J Biol Chem. 2002;277:38755-63 pubmed
Cisneros Aguirre M, Lopezcolorado F, Tsai L, Bhargava R, Stark J. The importance of DNAPKcs for blunt DNA end joining is magnified when XLF is weakened. Nat Commun. 2022;13:3662 pubmed publisher
Moalem Y, Malis Y, Voloshin K, Dukhovny A, Hirschberg K, Sklan E. Sandfly Fever Viruses Attenuate the Type I Interferon Response by Targeting the Phosphorylation of JAK-STAT Components. Front Immunol. 2022;13:865797 pubmed publisher
Wang Y, Ma B, Liu X, Gao G, Che Z, Fan M, et al. ZFP281-BRCA2 prevents R-loop accumulation during DNA replication. Nat Commun. 2022;13:3493 pubmed publisher
Marchi P, Marrone L, Brasseur L, Coens A, Webster C, Bousset L, et al. C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons. Life Sci Alliance. 2022;5: pubmed publisher
Mac Kain A, Maarifi G, Aicher S, Arhel N, Baidaliuk A, Munier S, et al. Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen. Nat Commun. 2022;13:2442 pubmed publisher
Courtellemont T, De Leo M, Gopaldass N, Mayer A. CROP: a retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system. EMBO J. 2022;41:e109646 pubmed publisher
Cabello Lobato M, Jenner M, Cisneros Aguirre M, Brüninghoff K, Sandy Z, da Costa I, et al. Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining. Nucleic Acids Res. 2022;50:4732-4754 pubmed publisher
Sathyanarayana S, Saunders J, Slaughter J, Tariq K, Chakrabarti R, Sadanandappa M, et al. Pten heterozygosity restores neuronal morphology in fragile X syndrome mice. Proc Natl Acad Sci U S A. 2022;119:e2109448119 pubmed publisher
Haimovici A, Hofer C, Badr M, Bavafaye Haghighi E, Amer T, Boerries M, et al. Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse. Cell Death Dis. 2022;13:315 pubmed publisher
Gogleva A, Polychronopoulos D, Pfeifer M, Poroshin V, Ughetto M, Martin M, et al. Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer. Nat Commun. 2022;13:1667 pubmed publisher
Takenoshita Y, Hara M, Fukagawa T. Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions. Nat Commun. 2022;13:851 pubmed publisher
Tan M, Li S, Juillard F, Chitas R, Custodio T, Xue H, et al. MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res. 2021;49:12895-12911 pubmed publisher
Park S, Frake R, Karabiyik C, Son S, Siddiqi F, Bento C, et al. Vinexin contributes to autophagic decline in brain ageing across species. Cell Death Differ. 2021;: pubmed publisher
Wang L, Proulx M, Kim A, Lelarge V, McCaffrey L. A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation. Sci Rep. 2021;11:22807 pubmed publisher
Nie L, He K, Xie F, Xiao S, Li S, Xu J, et al. Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer's disease. Aging (Albany NY). 2021;13:23739-23756 pubmed publisher
Basic M, Hertel A, Bajdzienko J, Bonn F, Tellechea M, Stolz A, et al. The deubiquitinase USP11 is a versatile and conserved regulator of autophagy. J Biol Chem. 2021;297:101263 pubmed publisher
Soto Faguás C, Sanchez Molina P, Saura C. Loss of presenilin function enhances tau phosphorylation and aggregation in mice. Acta Neuropathol Commun. 2021;9:162 pubmed publisher
Evron T, Caspi M, Kazelnik M, Shor Nareznoy Y, Armoza Eilat S, Kariv R, et al. A CRISPR knockout screen reveals new regulators of canonical Wnt signaling. Oncogenesis. 2021;10:63 pubmed publisher
Nicholas T, Metcalf S, Greulich B, Hollenhorst P. Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1. NAR Cancer. 2021;3:zcab033 pubmed publisher
Olbrich T, Vega Sendino M, Tillo D, Wu W, Zolnerowich N, Pavani R, et al. CTCF is a barrier for 2C-like reprogramming. Nat Commun. 2021;12:4856 pubmed publisher
Feliciano D, Ott C, Espinosa Medina I, Weigel A, Benedetti L, Milano K, et al. YAP1 nuclear efflux and transcriptional reprograming follow membrane diminution upon VSV-G-induced cell fusion. Nat Commun. 2021;12:4502 pubmed publisher
Nowicka U, Chrościcki P, Stroobants K, Sladowska M, Turek M, Uszczynska Ratajczak B, et al. Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins. elife. 2021;10: pubmed publisher
Li M, McGhee E, Shinno L, Lee K, Lin Y. Exposure to Microbial Metabolite Butyrate Prolongs the Survival Time and Changes the Growth Pattern of Human Papillomavirus 16 E6/E7-Immortalized Keratinocytes in Vivo. Am J Pathol. 2021;191:1822-1836 pubmed publisher
Ramirez Alvarez C, Kee C, Sharma A, Thomas L, Schmidt F, Stanifer M, et al. The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity. PLoS Pathog. 2021;17:e1009687 pubmed publisher
Zhang J, He X, Wu H, Zhang X, Yang S, Liu C, et al. Loss of DRC1 function leads to multiple morphological abnormalities of the sperm flagella and male infertility in human and mouse. Hum Mol Genet. 2021;: pubmed publisher
Hatzopoulos G, Kükenshöner T, Banterle N, Favez T, Flückiger I, Hamel V, et al. Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly. Nat Commun. 2021;12:3805 pubmed publisher
Dahlet T, Truss M, Frede U, Al Adhami H, Bardet A, Dumas M, et al. E2F6 initiates stable epigenetic silencing of germline genes during embryonic development. Nat Commun. 2021;12:3582 pubmed publisher
Scott G, Mahoney S, Scott M, Loureiro A, Lopez Ramirez A, Tanner J, et al. N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties. Amino Acids. 2021;53:1927-1939 pubmed publisher
Wright G, Sonavane M, Gassman N. Activated STAT3 Is a Novel Regulator of the XRCC1 Promoter and Selectively Increases XRCC1 Protein Levels in Triple Negative Breast Cancer. Int J Mol Sci. 2021;22: pubmed publisher
Meyer F, Goebel S, Spangel S, Leovsky C, Hoelzer D, Thierbach R. Metformin alters therapeutic effects in the BALB/c tumor therapy model. BMC Cancer. 2021;21:629 pubmed publisher
Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, et al. DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells. Theranostics. 2021;11:6355-6369 pubmed publisher
Kochanowski P, Catapano J, Pudełek M, Wrobel T, Madeja Z, Ryszawy D, et al. Temozolomide Induces the Acquisition of Invasive Phenotype by O6-Methylguanine-DNA Methyltransferase (MGMT)+ Glioblastoma Cells in a Snail-1/Cx43-Dependent Manner. Int J Mol Sci. 2021;22: pubmed publisher
Klouwer F, Falkenberg K, Ofman R, Koster J, van Gent D, Ferdinandusse S, et al. Autophagy Inhibitors Do Not Restore Peroxisomal Functions in Cells With the Most Common Peroxisome Biogenesis Defect. Front Cell Dev Biol. 2021;9:661298 pubmed publisher
Michaluk P, Heller J, Rusakov D. Rapid recycling of glutamate transporters on the astroglial surface. elife. 2021;10: pubmed publisher
Herrero Ruíz A, Martínez García P, Terron Bautista J, Millán Zambrano G, Lieberman J, Jimeno González S, et al. Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing. Cell Rep. 2021;35:108977 pubmed publisher
Giebel N, de Jaime Soguero A, García Del Arco A, Landry J, Tietje M, Villacorta L, et al. USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling. EMBO Rep. 2021;22:e51415 pubmed publisher
Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed publisher
Baxley R, Leung W, Schmit M, Matson J, Yin L, Oram M, et al. Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. Nat Commun. 2021;12:1626 pubmed publisher
Liu L, Lauro B, Wolfe M, Selkoe D. Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides. J Biol Chem. 2021;296:100393 pubmed publisher
Miskin R, Warren J, Ndoye A, Wu L, Lamar J, DiPersio C. Integrin α3β1 Promotes Invasive and Metastatic Properties of Breast Cancer Cells through Induction of the Brn-2 Transcription Factor. Cancers (Basel). 2021;13: pubmed publisher
Chen T, Huang B, Tang T, Chao Y, Xiao X, Lee P, et al. Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response. Cell Death Differ. 2021;: pubmed publisher
Fan X, Zeng Y, Fan Z, Cui L, Song W, Wu Q, et al. Dihydromyricetin promotes longevity and activates the transcription factors FOXO and AOP in Drosophila. Aging (Albany NY). 2020;13:460-476 pubmed publisher
Hachimi M, Grabowski C, Campanario S, Herranz G, Baonza G, Serrador J, et al. Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis. Curr Biol. 2020;: pubmed publisher
Cui L, Song W, Zeng Y, Wu Q, Fan Z, Huang T, et al. Deubiquitinase USP7 regulates Drosophila aging through ubiquitination and autophagy. Aging (Albany NY). 2020;12:23082-23095 pubmed publisher
Tomorsky J, Parker P, Doe C, Niell C. Precise levels of nectin-3 are required for proper synapse formation in postnatal visual cortex. Neural Dev. 2020;15:13 pubmed publisher
Ebert K, Zwingenberger G, Barbaria E, Keller S, Heck C, Arnold R, et al. Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines. BMC Cancer. 2020;20:1039 pubmed publisher
Saldana Caboverde A, Nissanka N, Garcia S, Lombes A, Diaz F. Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Eficient Cells. Cells. 2020;9: pubmed publisher
Chakravarti D, Hu B, Mao X, Rashid A, Li J, Li J, et al. Telomere dysfunction activates YAP1 to drive tissue inflammation. Nat Commun. 2020;11:4766 pubmed publisher
He Z, Duan Z, Chen L, Li B, Zhou Y. Long non-coding RNA Loc490 inhibits gastric cancer cell proliferation and metastasis by upregulating RNA-binding protein Quaking. Aging (Albany NY). 2020;12:17681-17693 pubmed publisher
Chen Y, Zhang P, Lin X, Zhang H, Miao J, Zhou Y, et al. Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats. Aging (Albany NY). 2020;12:17235-17256 pubmed publisher
Nakazawa K, Shichino Y, Iwasaki S, Shiina N. Implications of RNG140 (caprin2)-mediated translational regulation in eye lens differentiation. J Biol Chem. 2020;295:15029-15044 pubmed publisher
Shen J, Zhu X, Liu H. MiR-483 induces senescence of human adipose-derived mesenchymal stem cells through IGF1 inhibition. Aging (Albany NY). 2020;12:15756-15770 pubmed publisher
Yang R, Zhan M, Guo M, Yuan H, Wang Y, Zhang Y, et al. Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway. Cell Death Differ. 2020;: pubmed publisher
Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher
Geisinger J, Stearns T. CRISPR/Cas9 treatment causes extended TP53-dependent cell cycle arrest in human cells. Nucleic Acids Res. 2020;48:9067-9081 pubmed publisher
Bobkov G, Huang A, van den Berg S, Mitra S, Anselm E, Lazou V, et al. Spt6 is a maintenance factor for centromeric CENP-A. Nat Commun. 2020;11:2919 pubmed publisher
Bae B, Gruner H, Lynch M, Feng T, So K, Oliver D, et al. Elimination of Calm1 long 3' UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice. RNA. 2020;: pubmed publisher
Penas C, Apraiz A, Muñoa I, Arroyo Berdugo Y, Rasero J, Ezkurra P, et al. RKIP Regulates Differentiation-Related Features in Melanocytic Cells. Cancers (Basel). 2020;12: pubmed publisher
Yang A, Shao T, Bofill De Ros X, Lian C, Villanueva P, Dai L, et al. AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2. Nat Commun. 2020;11:2765 pubmed publisher
Valbuena Perez J, Linnenberger R, Dembek A, Bruscoli S, Riccardi C, Schulz M, et al. Altered glucocorticoid metabolism represents a feature of macroph-aging. Aging Cell. 2020;19:e13156 pubmed publisher
Bai G, Kermi C, Stoy H, Schiltz C, Bacal J, Zaino A, et al. HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis. Mol Cell. 2020;78:1237-1251.e7 pubmed publisher
Rickman K, Noonan R, Lach F, Sridhar S, Wang A, Abhyankar A, et al. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links. Genes Dev. 2020;34:832-846 pubmed publisher
Kiepas A, Voorand E, Senecal J, Ahn R, Annis M, Jacquet K, et al. The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation. J Biol Chem. 2020;: pubmed publisher
D Souza R, Woodhead J, Hedges C, Zeng N, Wan J, Kumagai H, et al. Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition. Aging (Albany NY). 2020;12:5244-5258 pubmed publisher
Nishiyama A, Mulholland C, Bultmann S, Kori S, Endo A, Saeki Y, et al. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nat Commun. 2020;11:1222 pubmed publisher
Luo H, Yu Q, Liu Y, Tang M, Liang M, Zhang D, et al. LATS kinase-mediated CTCF phosphorylation and selective loss of genomic binding. Sci Adv. 2020;6:eaaw4651 pubmed publisher
Wang Y, Maeda Y, Liu Y, Takada Y, Ninomiya A, Hirata T, et al. Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation. Nat Commun. 2020;11:860 pubmed publisher
Gulmez Karaca K, Kupke J, Brito D, Zeuch B, Thome C, Weichenhan D, et al. Neuronal ensemble-specific DNA methylation strengthens engram stability. Nat Commun. 2020;11:639 pubmed publisher
Mitra S, Bodor D, David A, Abdul Zani I, Mata J, Neumann B, et al. Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin. Nat Commun. 2020;11:501 pubmed publisher
Turchi R, Tortolici F, Guidobaldi G, Iacovelli F, Falconi M, Rufini S, et al. Frataxin deficiency induces lipid accumulation and affects thermogenesis in brown adipose tissue. Cell Death Dis. 2020;11:51 pubmed publisher
An H, Fan C, Sharif M, Kim D, Poitelon Y, Park Y. Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects. Sci Rep. 2020;10:814 pubmed publisher
Shan S, Xu F, Bleyer M, Becker S, Melbaum T, Wemheuer W, et al. Association of α/β-Hydrolase D16B with Bovine Conception Rate and Sperm Plasma Membrane Lipid Composition. Int J Mol Sci. 2020;21: pubmed publisher
Ramos H, Calheiros J, Almeida J, Barcherini V, Santos S, Carvalho A, et al. SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner. Int J Mol Sci. 2020;21: pubmed publisher
Zhang S, Liu Y, Huang Q, Yuan S, Liu H, Shi L, et al. Murine germ cell-specific disruption of Ift172 causes defects in spermiogenesis and male fertility. Reproduction. 2020;159:409-421 pubmed publisher
Wang D, Wu H, Phua S, Yang G, Qi Lim W, Gu L, et al. Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor. Nat Commun. 2020;11:357 pubmed publisher
Emidio G, Placidi M, Rea F, Rossi G, Falone S, Cristiano L, et al. Methylglyoxal-Dependent Glycative Stress and Deregulation of SIRT1 Functional Network in the Ovary of PCOS Mice. Cells. 2020;9: pubmed publisher
Hanniford D, Ulloa Morales A, Karz A, Berzoti Coelho M, Moubarak R, Sánchez Sendra B, et al. Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis. Cancer Cell. 2020;37:55-70.e15 pubmed publisher
Duan Y, Qiu Y, Huang X, Dai C, Yang J, He W. Deletion of FHL2 in fibroblasts attenuates fibroblasts activation and kidney fibrosis via restraining TGF-β1-induced Wnt/β-catenin signaling. J Mol Med (Berl). 2020;98:291-307 pubmed publisher
Iaea D, Spahr Z, Singh R, Chan R, Zhou B, Bareja R, et al. Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865:158609 pubmed publisher
Fierro Fernández M, Miguel V, Marquez Exposito L, Nuevo Tapioles C, Herrero J, Blanco Ruiz E, et al. MiR-9-5p protects from kidney fibrosis by metabolic reprogramming. FASEB J. 2020;34:410-431 pubmed publisher
You E, Ko P, Jeong J, Keum S, Kim J, Seo Y, et al. Dynein-mediated nuclear translocation of yes-associated protein through microtubule acetylation controls fibroblast activation. Cell Mol Life Sci. 2020;: pubmed publisher
Kundu A, Shelar S, Ghosh A, Ballestas M, Kirkman R, Nam H, et al. 14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation. J Biol Chem. 2020;295:1754-1766 pubmed publisher
Chao A, Chen C, Wu M, Hou B, Yang D. Roles of Id1/HIF-1 and CDK5/HIF-1 in cell cycle reentry induced by amyloid-beta peptide in post-mitotic cortical neuron. Biochim Biophys Acta Mol Cell Res. 2020;1867:118628 pubmed publisher
Nguyen A, Zhou J, Sicairos B, Sonney S, Du Y. Upregulation of CD73 Confers Acquired Radioresistance and is Required for Maintaining Irradiation-selected Pancreatic Cancer Cells in a Mesenchymal State. Mol Cell Proteomics. 2020;19:375-389 pubmed publisher
Di M, Wang M, Miao J, Chen B, Huang H, Lin C, et al. CHAF1B induces radioresistance by promoting DNA damage repair in nasopharyngeal carcinoma. Biomed Pharmacother. 2020;123:109748 pubmed publisher
Vymětalová L, Kučírková T, Knopfova L, Pospíšilová V, Kasko T, Lejdarova H, et al. Large-Scale Automated Hollow-Fiber Bioreactor Expansion of Umbilical Cord-Derived Human Mesenchymal Stromal Cells for Neurological Disorders. Neurochem Res. 2020;45:204-214 pubmed publisher
Zhang S, Zhang J, Wei D, An H, Liu W, Lai Y, et al. Dengzhan Shengmai capsules and their active component scutellarin prevent cognitive decline in APP/PS1 mice by accelerating Aβ aggregation and reducing oligomers formation. Biomed Pharmacother. 2020;121:109682 pubmed publisher
Oshima M, Pechberty S, Bellini L, Gopel S, Campana M, Rouch C, et al. Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity. Diabetologia. 2020;63:395-409 pubmed publisher
Palese F, Bonomi E, Nuzzo T, Benussi A, Mellone M, Zianni E, et al. Anti-GluA3 antibodies in frontotemporal dementia: effects on glutamatergic neurotransmission and synaptic failure. Neurobiol Aging. 2020;86:143-155 pubmed publisher
Kowal J, Schmal H, Halekoh U, Hjelmborg J, Kassem M. Single-cell high-content imaging parameters predict functional phenotype of cultured human bone marrow stromal stem cells. Stem Cells Transl Med. 2020;9:189-202 pubmed publisher
Tan J, Fourrière L, Wang J, Perez F, Boncompain G, Gleeson P. Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-β production. Mol Biol Cell. 2020;31:27-44 pubmed publisher
Alsabban A, Morikawa M, Tanaka Y, Takei Y, Hirokawa N. Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia-like phenotypes in mice. EMBO J. 2020;39:e101090 pubmed publisher
Xu X, Eshima S, Kato S, Fisher D, Sakurai H, Hayakawa Y, et al. Rational Combination Therapy for Melanoma with Dinaciclib by Targeting BAK-Dependent Cell Death. Mol Cancer Ther. 2020;19:627-636 pubmed publisher
Sieben C, Jeganathan K, Nelson G, Sturmlechner I, Zhang C, van Deursen W, et al. BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. J Clin Invest. 2020;130:171-188 pubmed publisher
Oh J, Park E, Song K, Bae G, Choi G. PHYTOCHROME INTERACTING FACTOR8 Inhibits Phytochrome A-Mediated Far-Red Light Responses in Arabidopsis. Plant Cell. 2020;32:186-205 pubmed publisher
Jubrail J, Africano Gomez K, Herit F, Mularski A, Bourdoncle P, Oberg L, et al. Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus. EMBO Rep. 2020;21:e47963 pubmed publisher
Pistono C, Monti M, Boiocchi C, Berzolari F, Osera C, Mallucci G, et al. Response to oxidative stress of peripheral blood mononuclear cells from multiple sclerosis patients and healthy controls. Cell Stress Chaperones. 2020;25:81-91 pubmed publisher
Herhaus L, Bhaskara R, Lystad A, Gestal Mato U, Covarrubias Pinto A, Bonn F, et al. TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease. EMBO Rep. 2020;21:e48317 pubmed publisher
Bousquet Mur E, Bernardo S, Papon L, Mancini M, Fabbrizio E, Goussard M, et al. Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma. J Clin Invest. 2020;130:612-624 pubmed publisher
Ishii Y, Taguchi A, Kukimoto I. The homeobox transcription factor HOXC13 upregulates human papillomavirus E1 gene expression and contributes to viral genome maintenance. FEBS Lett. 2020;594:751-762 pubmed publisher
Ryszawy D, Pudełek M, Kochanowski P, Janik Olchawa N, Bogusz J, Rąpała M, et al. High bisphenol A concentrations augment the invasiveness of tumor cells through Snail-1/Cx43/ERRγ-dependent epithelial-mesenchymal transition. Toxicol In Vitro. 2020;62:104676 pubmed publisher
Baby N, Alagappan N, Dheen S, Sajikumar S. MicroRNA-134-5p inhibition rescues long-term plasticity and synaptic tagging/capture in an Aβ(1-42)-induced model of Alzheimer's disease. Aging Cell. 2020;19:e13046 pubmed publisher
Rein B, Yan Z, Wang Z. Diminished social interaction incentive contributes to social deficits in mouse models of autism spectrum disorder. Genes Brain Behav. 2020;19:e12610 pubmed publisher
Palencia Campos A, Martínez Fernández M, Altunoglu U, Soto Bielicka P, Torres A, Marín P, et al. Heterozygous pathogenic variants in GLI1 are a common finding in isolated postaxial polydactyly A/B. Hum Mutat. 2020;41:265-276 pubmed publisher
Odeh M, Tamir Livne Y, Haas T, Bengal E. P38α MAPK coordinates the activities of several metabolic pathways that together induce atrophy of denervated muscles. FEBS J. 2020;287:73-93 pubmed publisher
Cebrià Costa J, Pascual Reguant L, Gonzalez Perez A, Serra Bardenys G, Querol J, Cosín M, et al. LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells. Oncogene. 2020;39:79-121 pubmed publisher
Feng Q, Luo Y, Zhang X, Yang X, Hong X, Sun D, et al. MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. Autophagy. 2020;16:641-658 pubmed publisher
Varga J, Dér N, Zsindely N, Bodai L. Green tea infusion alleviates neurodegeneration induced by mutant Huntingtin in Drosophila. Nutr Neurosci. 2020;23:183-189 pubmed publisher
Pepin M, Koentges C, Pfeil K, Gollmer J, Kersting S, Wiese S, et al. Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1. Front Endocrinol (Lausanne). 2019;10:872 pubmed publisher
Schaub T, Gürgen D, Maus D, Lange C, Tarabykin V, Dragun D, et al. mTORC1 and mTORC2 Differentially Regulate Cell Fate Programs to Coordinate Osteoblastic Differentiation in Mesenchymal Stromal Cells. Sci Rep. 2019;9:20071 pubmed publisher
Lorenzon I, Pellarin I, Pellizzari I, D Andrea S, Belletti B, Sonego M, et al. Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells. Cells. 2019;9: pubmed publisher
Schmeisser S, Li S, Bouchard B, Ruiz M, Des Rosiers C, Roy R. Muscle-Specific Lipid Hydrolysis Prolongs Lifespan through Global Lipidomic Remodeling. Cell Rep. 2019;29:4540-4552.e8 pubmed publisher
Lee H, Lee K, Chen C, Lee T. Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer's disease. J Neuroinflammation. 2019;16:267 pubmed publisher
Lee D, Hokinson D, Park S, Elvira R, Kusuma F, Lee J, et al. ER Stress Induces Cell Cycle Arrest at the G2/M Phase Through eIF2α Phosphorylation and GADD45α. Int J Mol Sci. 2019;20: pubmed publisher
Park S, Kang N, Song E, Wie M, Lee E, Hwang S, et al. ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress. Nat Commun. 2019;10:5718 pubmed publisher
Jonker C, Deo C, Zager P, Tkachuk A, Weinstein A, Rodriguez Boulan E, et al. Accurate measurement of fast endocytic recycling kinetics in real time. J Cell Sci. 2019;: pubmed publisher
Hussain S, Bedekovics T, Ali A, Zaid O, May D, Roux K, et al. A cysteine near the C-terminus of UCH-L1 is dispensable for catalytic activity but is required to promote AKT phosphorylation, eIF4F assembly, and malignant B-cell survival. Cell Death Discov. 2019;5:152 pubmed publisher
Young R, Ewan K, Ferrer V, Allende M, Godovac Zimmermann J, Dale T, et al. Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. elife. 2019;8: pubmed publisher
Casanova M, Moscatelli M, Chauvière L, Huret C, Samson J, Liyakat Ali T, et al. A primate-specific retroviral enhancer wires the XACT lncRNA into the core pluripotency network in humans. Nat Commun. 2019;10:5652 pubmed publisher
Kouloulia S, Hallin E, Simbriger K, Amorim I, Lach G, Amvrosiadis T, et al. Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. Cell Rep. 2019;29:3620-3635.e7 pubmed publisher
Sabatino M, Castellaro A, Racca A, Carbajosa González S, Pansa M, Soria G, et al. Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence. Front Cell Dev Biol. 2019;7:297 pubmed publisher
Ferron M, Cadiet J, Persello A, Prat V, Denis M, Erraud A, et al. O-GlcNAc stimulation: A new metabolic approach to treat septic shock. Sci Rep. 2019;9:18751 pubmed publisher
Napoli B, Gumeni S, Forgiarini A, Fantin M, De Filippis C, Panzeri E, et al. Naringenin Ameliorates Drosophila ReepA Hereditary Spastic Paraplegia-Linked Phenotypes. Front Neurosci. 2019;13:1202 pubmed publisher
Pancholi S, Leal M, Ribas R, Simigdala N, Schuster E, Chateau Joubert S, et al. Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer. Breast Cancer Res. 2019;21:135 pubmed publisher
Schäfer I, Kaisler J, Scheller A, Kirchhoff F, Haghikia A, Faissner A. Conditional Deletion of LRP1 Leads to Progressive Loss of Recombined NG2-Expressing Oligodendrocyte Precursor Cells in a Novel Mouse Model. Cells. 2019;8: pubmed publisher
Bosseboeuf A, Baron A, Duval E, Gautier A, Sourdaine P, Auvray P. K092A and K092B, Two Peptides Isolated from the Dogfish (Scyliorhinus canicula L.), with Potential Antineoplastic Activity Against Human Prostate and Breast Cancer Cells. Mar Drugs. 2019;17: pubmed publisher
Delviks Frankenberry K, Ackerman D, Timberlake N, Hamscher M, Nikolaitchik O, HU W, et al. Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G. Mol Ther Nucleic Acids. 2019;18:1023-1038 pubmed publisher
Albig C, Wang C, Dann G, Wojcik F, Schauer T, Krause S, et al. JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. Nat Commun. 2019;10:5343 pubmed publisher
Piriya Ananda Babu L, Wang H, Eguchi K, Guillaud L, Takahashi T. Microtubule and Actin Differentially Regulate Synaptic Vesicle Cycling to Maintain High-frequency Neurotransmission. J Neurosci. 2019;: pubmed publisher
Ferrari R, de Llobet Cucalon L, Di Vona C, Le Dilly F, Vidal E, Lioutas A, et al. TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation. Mol Cell. 2019;: pubmed publisher
Cisse O, Quraishi M, Gulluni F, Guffanti F, Mavrommati I, Suthanthirakumaran M, et al. Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth. J Exp Clin Cancer Res. 2019;38:472 pubmed publisher
Hwang J, Seo J, Beshiri M, Wankowicz S, Liu D, Cheung A, et al. CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer. Cell Rep. 2019;29:2355-2370.e6 pubmed publisher
Ljepoja B, Schreiber C, Gegenfurtner F, García Román J, Köhler B, Zahler S, et al. Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A. PLoS ONE. 2019;14:e0224314 pubmed publisher
Madhukar N, Khade P, Huang L, Gayvert K, Galletti G, Stogniew M, et al. A Bayesian machine learning approach for drug target identification using diverse data types. Nat Commun. 2019;10:5221 pubmed publisher
Zurlo G, Liu X, Takada M, Fan C, Simon J, Ptacek T, et al. Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer. Nat Commun. 2019;10:5177 pubmed publisher
Montero J, Gstalder C, Kim D, Sadowicz D, Miles W, Manos M, et al. Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies. Nat Commun. 2019;10:5157 pubmed publisher
Nagati J, Xu M, Garcia T, Comerford S, Hammer R, Garcia J. A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling. PLoS ONE. 2019;14:e0225105 pubmed publisher
Huang Q, Chan K, Tobey I, Chan Y, Poterba T, Boutros C, et al. Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids. PLoS ONE. 2019;14:e0225206 pubmed publisher
Hua R, Wei H, Liu C, Zhang Y, Liu S, Guo Y, et al. FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis. Nucleic Acids Res. 2019;47:11755-11770 pubmed publisher
Murányi J, Varga A, Gyulavári P, Pénzes K, Németh C, Csala M, et al. Novel Crizotinib-GnRH Conjugates Revealed the Significance of Lysosomal Trapping in GnRH-Based Drug Delivery Systems. Int J Mol Sci. 2019;20: pubmed publisher
Marcozzi S, Rossi V, Salvatore G, Di Rella F, De Felici M, Klinger F. Distinct effects of epirubicin, cisplatin and cyclophosphamide on ovarian somatic cells of prepuberal ovaries. Aging (Albany NY). 2019;11:10532-10556 pubmed publisher
Millen S, Gross C, Donhauser N, Mann M, Peloponese J, Thoma Kress A. Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission. Front Microbiol. 2019;10:2439 pubmed publisher
Hatanaka Y, Kawasaki T, Abe T, Shioi G, Kohno T, Hattori M, et al. Semaphorin 6A-Plexin A2/A4 Interactions with Radial Glia Regulate Migration Termination of Superficial Layer Cortical Neurons. iScience. 2019;21:359-374 pubmed publisher
Baron O, Grieshober D, Dias C, Fanto M. Fat cadherins in mouse models of degenerative ataxias. Sci Rep. 2019;9:16155 pubmed publisher
Abaffy P, Tomankova S, Naraine R, Kubista M, Sindelka R. The role of nitric oxide during embryonic wound healing. BMC Genomics. 2019;20:815 pubmed publisher
Osada A, Endo K, Kimura Y, Sakamoto K, Nakamura R, Sakamoto K, et al. Addiction of mesenchymal phenotypes on the FGF/FGFR axis in oral squamous cell carcinoma cells. PLoS ONE. 2019;14:e0217451 pubmed publisher
Miah S, Banks C, Ogunbolude Y, Bagu E, Berg J, Saraf A, et al. BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential. Sci Adv. 2019;5:eaaw3113 pubmed publisher
Dudka D, Castrogiovanni C, Liaudet N, Vassal H, Meraldi P. Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics. Curr Biol. 2019;29:3563-3578.e6 pubmed publisher
Bott A, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang Y, et al. Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Rep. 2019;29:1287-1298.e6 pubmed publisher
Sommer A, Falcenberg M, Ljepoja B, Frohlich T, Arnold G, Wagner E, et al. Downregulation of GRK5 hampers the migration of breast cancer cells. Sci Rep. 2019;9:15548 pubmed publisher
Laforet P, Inoue M, Goillot E, Lefeuvre C, Cagin U, Streichenberger N, et al. Deep morphological analysis of muscle biopsies from type III glycogenesis (GSDIII), debranching enzyme deficiency, revealed stereotyped vacuolar myopathy and autophagy impairment. Acta Neuropathol Commun. 2019;7:167 pubmed publisher
Jiang J, Srivastava S, Seim G, Pavlova N, King B, Zou L, et al. Promoter demethylation of the asparagine synthetase gene is required for ATF4-dependent adaptation to asparagine depletion. J Biol Chem. 2019;294:18674-18684 pubmed publisher
Zhou D, Fu H, Han Y, Zhang L, Liu S, Lin L, et al. Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis. JCI Insight. 2019;4: pubmed publisher
Wang C, Su M, Cheng H, Kuo P, Tsai P. Fetuin-A Inhibits Placental Cell Growth and Ciliogenesis in Gestational Diabetes Mellitus. Int J Mol Sci. 2019;20: pubmed publisher
Srikantan S, Deng Y, Cheng Z, Luo A, Qin Y, Gao Q, et al. The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner. Nat Commun. 2019;10:4720 pubmed publisher
Bosseboeuf A, Baron A, Duval E, Gautier A, Sourdaine P, Auvray P. A Potential Antineoplastic Peptide of Human Prostate Cancer Cells Derived from the Lesser Spotted Dogfish (Scyliorhinus canicula L.). Mar Drugs. 2019;17: pubmed publisher
Kumari A, Srivastava S, Manne R, Sisodiya S, Santra M, Guchhait S, et al. C12, a combretastatin-A4 analog, exerts anticancer activity by targeting microtubules. Biochem Pharmacol. 2019;170:113663 pubmed publisher
Leon Aparicio D, Salvador C, Aparicio Trejo O, Briones Herrera A, Pedraza Chaverri J, Vaca L, et al. Novel Potassium Channels in Kidney Mitochondria: The Hyperpolarization-Activated and Cyclic Nucleotide-Gated HCN Channels. Int J Mol Sci. 2019;20: pubmed publisher
Eshelman M, Matthews S, Schleicher E, Fleeman R, Kawasawa Y, Stumpo D, et al. Tristetraprolin targets Nos2 expression in the colonic epithelium. Sci Rep. 2019;9:14413 pubmed publisher
Moss Taylor L, Upadhyay A, Pan X, Kim M, O Connor M. Body Size and Tissue-Scaling Is Regulated by Motoneuron-Derived Activinß in Drosophila melanogaster. Genetics. 2019;213:1447-1464 pubmed publisher
Mousavi S, Skjeldal F, Fønhus M, Haugen L, Eskild W, Berg T, et al. Receptor-Mediated Endocytosis of VEGF-A in Rat Liver Sinusoidal Endothelial Cells. Biomed Res Int. 2019;2019:5496197 pubmed publisher
Sarraf S, Sideris D, Giagtzoglou N, Ni L, Kankel M, Sen A, et al. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Rep. 2019;29:225-235.e5 pubmed publisher
Azzi Martin L, He W, Péré Védrenne C, Korolik V, Alix C, Prochazkova Carlotti M, et al. Cytolethal distending toxin induces the formation of transient messenger-rich ribonucleoprotein nuclear invaginations in surviving cells. PLoS Pathog. 2019;15:e1007921 pubmed publisher
Codony Servat J, Viteri S, Codony Servat C, Ito M, Bracht J, Berenguer J, et al. Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines. Transl Lung Cancer Res. 2019;8:340-351 pubmed publisher
Pauleau A, Bergner A, Kajtez J, Erhardt S. The checkpoint protein Zw10 connects CAL1-dependent CENP-A centromeric loading and mitosis duration in Drosophila cells. PLoS Genet. 2019;15:e1008380 pubmed publisher
Lucà R, di Blasio G, Gallo D, Monteleone V, Manni I, Fici L, et al. Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4. Cancers (Basel). 2019;11: pubmed publisher
Keller B, Maier J, Weldle M, Segan S, Traenkle B, Rothbauer U. A Strategy to Optimize the Generation of Stable Chromobody Cell Lines for Visualization and Quantification of Endogenous Proteins in Living Cells. Antibodies (Basel). 2019;8: pubmed publisher
He J, Wink S, de Bont H, Le Dévédec S, Zhang Y, van de Water B. FRET biosensor-based kinase inhibitor screen for ERK and AKT activity reveals differential kinase dependencies for proliferation in TNBC cells. Biochem Pharmacol. 2019;169:113640 pubmed publisher
van der Noord V, McLaughlin R, Smid M, Foekens J, Martens J, Zhang Y, et al. An increased cell cycle gene network determines MEK and Akt inhibitor double resistance in triple-negative breast cancer. Sci Rep. 2019;9:13308 pubmed publisher
Asai Y, Fukuchi K, Tanno Y, Koitabashi Kiyozuka S, Kiyozuka T, Noda Y, et al. Aurora B kinase activity is regulated by SET/TAF1 on Sgo2 at the inner centromere. J Cell Biol. 2019;218:3223-3236 pubmed publisher
Campbell S, Amin M, Varma D, Bidone T. Computational model demonstrates that Ndc80-associated proteins strengthen kinetochore-microtubule attachments in metaphase. Cytoskeleton (Hoboken). 2019;76:549-561 pubmed publisher
Zhou H, Zheng T, Wang T, Li Q, Wang F, Liang X, et al. CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment. BMC Biol. 2019;17:73 pubmed publisher
Franchini L, Stanic J, Ponzoni L, Mellone M, Carrano N, Musardo S, et al. Linking NMDA Receptor Synaptic Retention to Synaptic Plasticity and Cognition. iScience. 2019;19:927-939 pubmed publisher
Vardhana S, Arnold P, Rosen B, Chen Y, Carey B, Huangfu D, et al. Glutamine independence is a selectable feature of pluripotent stem cells. Nat Metab. 2019;1:676-687 pubmed publisher
Spracklen A, Lamb M, Groen C, Tootle T. Pharmaco-Genetic Screen To Uncover Actin Regulators Targeted by Prostaglandins During Drosophila Oogenesis. G3 (Bethesda). 2019;9:3555-3565 pubmed publisher
Olah J, Szunyogh S, Szénási T, Szaniszlo T, Szabó A, Lehotzky A, et al. Interactions between two regulatory proteins of microtubule dynamics, HDAC6, TPPP/p25, and the hub protein, DYNLL/LC8. Biochim Biophys Acta Mol Cell Res. 2019;1866:118556 pubmed publisher
Zhao W, Cao L, Ying H, Zhang W, Li D, Zhu X, et al. Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition. Cell Res. 2019;29:895-910 pubmed publisher
Steinparzer I, Sedlyarov V, Rubin J, Eislmayr K, Galbraith M, Levandowski C, et al. Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Mol Cell. 2019;76:485-499.e8 pubmed publisher
Grudina C, Kouroupi G, Nonaka T, Hasegawa M, Matsas R, Zurzolo C. Human NPCs can degrade α-syn fibrils and transfer them preferentially in a cell contact-dependent manner possibly through TNT-like structures. Neurobiol Dis. 2019;132:104609 pubmed publisher
Walker R, Keynton J, Grimes D, Sreekumar V, Williams D, Esapa C, et al. Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model. Nat Commun. 2019;10:4072 pubmed publisher
Pan D, Walstein K, Take A, Bier D, Kaiser N, Musacchio A. Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing. Nat Commun. 2019;10:4046 pubmed publisher
Greenberg R, Long H, Swigut T, Wysocka J. Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome. Cell. 2019;178:1421-1436.e24 pubmed publisher
Roesler M, Lombino F, Freitag S, Schweizer M, Hermans Borgmeyer I, Schwarz J, et al. Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization. Front Cell Neurosci. 2019;13:330 pubmed publisher
Schneeberger P, Bierhals T, Neu A, Hempel M, Kutsche K. de novo MEPCE nonsense variant associated with a neurodevelopmental disorder causes disintegration of 7SK snRNP and enhanced RNA polymerase II activation. Sci Rep. 2019;9:12516 pubmed publisher
Niu J, Sun Y, Chen B, Zheng B, Jarugumilli G, Walker S, et al. Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation. Nature. 2019;573:139-143 pubmed publisher
Rouillon C, Depince A, Chenais N, Le Bail P, Labbe C. Somatic cell nuclear transfer in non-enucleated goldfish oocytes: understanding DNA fate during oocyte activation and first cellular division. Sci Rep. 2019;9:12462 pubmed publisher
Ganesan S, Roy C. Host cell depletion of tryptophan by IFNγ-induced Indoleamine 2,3-dioxygenase 1 (IDO1) inhibits lysosomal replication of Coxiella burnetii. PLoS Pathog. 2019;15:e1007955 pubmed publisher
Rathod M, Chatterjee S, Dutta S, Kalraiya R, Bhattacharyya D, De A. Mannose glycosylation is an integral step for NIS localization and function in human breast cancer cells. J Cell Sci. 2019;132: pubmed publisher
Sheng X, Li Y, Li Y, Liu W, Lu Z, Zhan J, et al. PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer stem cell-like characteristics. BMC Cancer. 2019;19:840 pubmed publisher
Schipper K, Seinstra D, Paulien Drenth A, van der Burg E, Ramovs V, Sonnenberg A, et al. Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin. Nat Commun. 2019;10:3800 pubmed publisher
Miller C, Wells R, McKenzie N, Trick M, Ball J, Fatihi A, et al. Variation in Expression of the HECT E3 Ligase UPL3 Modulates LEC2 Levels, Seed Size, and Crop Yields in Brassica napus. Plant Cell. 2019;31:2370-2385 pubmed publisher
Gómez H L, Felipe Medina N, Condezo Y, García Valiente R, Ramos I, Suja J, et al. The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility. PLoS Genet. 2019;15:e1008316 pubmed publisher
Pinto C, Khandekar A, Bhavna R, Kiesel P, Pigino G, Sonawane M. Microridges are apical epithelial projections formed of F-actin networks that organize the glycan layer. Sci Rep. 2019;9:12191 pubmed publisher
Guo L, Mohd K, Ren H, Xin G, Jiang Q, Clarke P, et al. Phosphorylation of importin-α1 by CDK1-cyclin B1 controls mitotic spindle assembly. J Cell Sci. 2019;132: pubmed publisher
Kim J, Wojcik M, Wang Y, Moon S, Zin E, Marnani N, et al. Oblique-plane single-molecule localization microscopy for tissues and small intact animals. Nat Methods. 2019;16:853-857 pubmed publisher
Swartz S, McKay L, Su K, Bury L, Padeganeh A, Maddox P, et al. Quiescent Cells Actively Replenish CENP-A Nucleosomes to Maintain Centromere Identity and Proliferative Potential. Dev Cell. 2019;51:35-48.e7 pubmed publisher
Ranjan P, Awasthi M, Snell W. Transient Internalization and Microtubule-Dependent Trafficking of a Ciliary Signaling Receptor from the Plasma Membrane to the Cilium. Curr Biol. 2019;29:2942-2947.e2 pubmed publisher
Fung T, Ji W, Higgs H, Chakrabarti R. Two distinct actin filament populations have effects on mitochondria, with differences in stimuli and assembly factors. J Cell Sci. 2019;132: pubmed publisher
Zhuo H, Zhou D, Wang Y, Mo H, Yu Y, Liu Y. Sonic hedgehog selectively promotes lymphangiogenesis after kidney injury through noncanonical pathway. Am J Physiol Renal Physiol. 2019;317:F1022-F1033 pubmed publisher
Xiao L, Chen Y, Yuan Y, Xu B, Gao Q, Chen P, et al. PC-1 NF suppresses high glucose-stimulated inflammation and extracellular matrix accumulation in glomerular mesangial cells via the Wnt/β-catenin signaling. Exp Ther Med. 2019;18:2029-2036 pubmed publisher
Zeeshan M, Ferguson D, Abel S, Burrrell A, Rea E, Brady D, et al. Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission. Life Sci Alliance. 2019;2: pubmed publisher
Gąsiorowski L, Furu A, Hejnol A. Morphology of the nervous system of monogonont rotifer Epiphanes senta with a focus on sexual dimorphism between feeding females and dwarf males. Front Zool. 2019;16:33 pubmed publisher
Hoppstädter J, Dembek A, Linnenberger R, Dahlem C, Barghash A, Fecher Trost C, et al. Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide. Front Immunol. 2019;10:1634 pubmed publisher
Lauzier A, Normandeau Guimond J, Vaillancourt Lavigueur V, Boivin V, Charbonneau M, Rivard N, et al. Colorectal cancer cells respond differentially to autophagy inhibition in vivo. Sci Rep. 2019;9:11316 pubmed publisher
Nader K, Krysiak A, Beroun A, Pekala M, Szymanska M, Kuzniewska B, et al. Loss of serum response factor in mature neurons in the dentate gyrus alters the morphology of dendritic spines and hippocampus-dependent behavioral tasks. Brain Struct Funct. 2019;224:2691-2701 pubmed publisher
Bloodgood R, Tetreault J, Sloboda R. The Chlamydomonas flagellar membrane glycoprotein FMG-1B is necessary for expression of force at the flagellar surface. J Cell Sci. 2019;132: pubmed publisher
Yeoh L, Goodman C, Mollard V, McHugh E, Lee V, Sturm A, et al. Alternative splicing is required for stage differentiation in malaria parasites. Genome Biol. 2019;20:151 pubmed publisher
Marrugal A, Ferrer I, Pastor M, Ojeda L, Quintanal Villalonga Á, Carnero A, et al. Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry. Cells. 2019;8: pubmed publisher
Cabrera E, Raninga P, Khanna K, Freire R. GSK3-β Stimulates Claspin Degradation via β-TrCP Ubiquitin Ligase and Alters Cancer Cell Survival. Cancers (Basel). 2019;11: pubmed publisher
Quesada López T, Gavaldà Navarro A, Morón Ros S, Campderros L, Iglesias R, Giralt M, et al. GPR120 controls neonatal brown adipose tissue thermogenic induction. Am J Physiol Endocrinol Metab. 2019;317:E742-E750 pubmed publisher
Logsdon G, Gambogi C, Liskovykh M, Barrey E, Larionov V, Miga K, et al. Human Artificial Chromosomes that Bypass Centromeric DNA. Cell. 2019;178:624-639.e19 pubmed publisher
Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, et al. Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes. Nat Commun. 2019;10:3312 pubmed publisher
Tomay F, Marinelli A, Leoni V, Caccia C, Matros A, Mock H, et al. Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice. J Transl Med. 2019;17:237 pubmed publisher
McMahon K, Wu Y, Gambin Y, Sierecki E, Tillu V, HALL T, et al. Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis. Nat Commun. 2019;10:3279 pubmed publisher
Kazakevych J, Stoyanova E, Liebert A, Varga Weisz P. Transcriptome analysis identifies a robust gene expression program in the mouse intestinal epithelium on aging. Sci Rep. 2019;9:10410 pubmed publisher
Kumar A, Shutova M, Tanaka K, Iwamoto D, Calderwood D, Svitkina T, et al. Filamin A mediates isotropic distribution of applied force across the actin network. J Cell Biol. 2019;218:2481-2491 pubmed publisher
Olbrich T, Vega Sendino M, Murga M, de Carcer G, Malumbres M, Ortega S, et al. A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells. Cell Rep. 2019;28:597-604.e4 pubmed publisher
Wood K, Rowlands C, Qureshi W, Thomas H, Buczek W, Briggs T, et al. Disease modeling of core pre-mRNA splicing factor haploinsufficiency. Hum Mol Genet. 2019;28:3704-3723 pubmed publisher
Runwal G, Stamatakou E, Siddiqi F, Puri C, Zhu Y, Rubinsztein D. LC3-positive structures are prominent in autophagy-deficient cells. Sci Rep. 2019;9:10147 pubmed publisher
Wang S, Lin H, Chen Y, Hsu T, Chuang J, Kao T, et al. CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation. J Neuroinflammation. 2019;16:146 pubmed publisher
Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed publisher
Mandati V, Del Maestro L, Dingli F, Lombard B, Loew D, Molinie N, et al. Phosphorylation of Merlin by Aurora A kinase appears necessary for mitotic progression. J Biol Chem. 2019;294:12992-13005 pubmed publisher
Kute P, Ramakrishna S, Neelagandan N, Chattarji S, Muddashetty R. NMDAR mediated translation at the synapse is regulated by MOV10 and FMRP. Mol Brain. 2019;12:65 pubmed publisher
Nogueira Recalde U, Lorenzo Gómez I, Blanco F, Loza M, Grassi D, Shirinsky V, et al. Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy. EBioMedicine. 2019;45:588-605 pubmed publisher
Koedoot E, Fokkelman M, Rogkoti V, Smid M, van de Sandt I, de Bont H, et al. Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes. Nat Commun. 2019;10:2983 pubmed publisher
Van Haute L, Lee S, McCann B, Powell C, Bansal D, Vasiliauskaite L, et al. NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs. Nucleic Acids Res. 2019;47:8720-8733 pubmed publisher
Lee M, Hwang Y, Yoon J, Sun J, Harned A, Nagashima K, et al. Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled. J Cell Biol. 2019;: pubmed publisher
Wagner W, Lippmann K, Heisler F, Gromova K, Lombino F, Roesler M, et al. Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. Cell Rep. 2019;28:11-20.e9 pubmed publisher
Zhang Y, Du X, Liu M, Tang F, Zhang P, Ai C, et al. Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy. Cell Res. 2019;29:609-627 pubmed publisher
Platanitis E, Demiröz D, Schneller A, Fischer K, Capelle C, Hartl M, et al. A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription. Nat Commun. 2019;10:2921 pubmed publisher
McLaughlin R, He J, van der Noord V, Redel J, Foekens J, Martens J, et al. A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy. Breast Cancer Res. 2019;21:77 pubmed publisher
Chiticariu E, Regamey A, Huber M, Hohl D. CENPV is a CYLD-interacting molecule regulating ciliary acetylated α-tubulin. J Invest Dermatol. 2019;: pubmed publisher
Brkić Z, Milosavljevic M, Glavonic E, Adzic M. Mitochondrial signaling in inflammation-induced depressive behavior in female and male rats: The role of glucocorticoid receptor. Brain Res Bull. 2019;150:317-327 pubmed publisher
Manning C, Biga V, Boyd J, Kursawe J, Ymisson B, Spiller D, et al. Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis. Nat Commun. 2019;10:2835 pubmed publisher
Rageot D, Bohnacker T, Keles E, McPhail J, Hoffmann R, Melone A, et al. (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase. J Med Chem. 2019;62:6241-6261 pubmed publisher
Tettey T, Gao X, Shao W, Li H, Story B, Chitsazan A, et al. A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing. Cell Rep. 2019;27:3770-3779.e7 pubmed publisher
Feldmann L, Le Prieult F, Felzen V, Thal S, Engelhard K, Behl C, et al. Proteasome and Autophagy-Mediated Impairment of Late Long-Term Potentiation (l-LTP) after Traumatic Brain Injury in the Somatosensory Cortex of Mice. Int J Mol Sci. 2019;20: pubmed publisher
Najafov A, Mookhtiar A, Luu H, Ordureau A, Pan H, Amin P, et al. TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL. Mol Cell. 2019;: pubmed publisher
Li J, Ma C, Long F, Yang D, Liu X, Hu Y, et al. Parkin Impairs Antiviral Immunity by Suppressing the Mitochondrial Reactive Oxygen Species-Nlrp3 Axis and Antiviral Inflammation. iScience. 2019;16:468-484 pubmed publisher
Martín Cortázar C, Chiodo Y, Jiménez P R, Bernabé M, Cayuela M, Iglesias T, et al. CDCA7 finely tunes cytoskeleton dynamics to promote lymphoma migration and invasion. Haematologica. 2019;: pubmed publisher
Li G, Wang M, Ren L, Li H, Liu Q, Ouyang Y, et al. Regulator of G protein signaling 20 promotes proliferation and migration in bladder cancer via NF-κB signaling. Biomed Pharmacother. 2019;117:109112 pubmed publisher
Piacentini L, Marchetti M, Bucciarelli E, Casale A, Cappucci U, Bonifazi P, et al. A role of the Trx-G complex in Cid/CENP-A deposition at Drosophila melanogaster centromeres. Chromosoma. 2019;: pubmed publisher
Dankner M, Ouellet V, Communal L, Schmitt E, Perkins D, Annis M, et al. CCN3/Nephroblastoma Overexpressed Is a Functional Mediator of Prostate Cancer Bone Metastasis That Is Associated with Poor Patient Prognosis. Am J Pathol. 2019;189:1451-1461 pubmed publisher
Morii K, Yamasaki S, Doi S, Irifuku T, Sasaki K, Doi T, et al. microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress. PLoS ONE. 2019;14:e0218468 pubmed publisher
Zhu L, Liao S, Fukunaga R. Drosophila Regnase-1 RNase is required for mRNA and miRNA profile remodelling during larva-to-adult metamorphosis. RNA Biol. 2019;16:1386-1400 pubmed publisher
Alcala S, Martinelli P, Hermann P, Heeschen C, Sainz B. The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures. Stem Cells Int. 2019;2019:1378639 pubmed publisher
Singh P, Roukounakis A, Weber A, Das K, Sohm B, Villunger A, et al. Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim. Cell Death Differ. 2019;: pubmed publisher
Trapp Fragnet L, Courvoisier K, Remy S, Pape G, Loustalot F, Denesvre C. Identification of Marek's Disease Virus VP22 Tegument Protein Domains Essential for Virus Cell-to-Cell Spread, Nuclear Localization, Histone Association and Cell-Cycle Arrest. Viruses. 2019;11: pubmed publisher
Alfano D, Altomonte A, Cortes C, Bilio M, Kelly R, Baldini A. Tbx1 regulates extracellular matrix-cell interactions in the second heart field. Hum Mol Genet. 2019;28:2295-2308 pubmed publisher
Li G, Jin D, Zhong T. Tubgcp3 Is Required for Retinal Progenitor Cell Proliferation During Zebrafish Development. Front Mol Neurosci. 2019;12:126 pubmed publisher
Good A, Haemmerle M, Oguh A, Doliba N, Stoffers D. Metabolic stress activates an ERK/hnRNPK/DDX3X pathway in pancreatic β cells. Mol Metab. 2019;: pubmed publisher
Whitfield M, Thomas L, Bequignon E, Schmitt A, Stouvenel L, Montantin G, et al. Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia. Am J Hum Genet. 2019;: pubmed publisher
Kono K, Yoshiura S, Fujita I, Okada Y, Shitamukai A, Shibata T, et al. Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization. elife. 2019;8: pubmed publisher
Magre I, Fandade V, Damle I, Banerjee P, Yadav S, Sonawane M, et al. Nup358 regulates microridge length by controlling SUMOylation-dependent activity of aPKC in zebrafish epidermis. J Cell Sci. 2019;132: pubmed publisher
Liu Y, Sugiura Y, Sudhof T, Lin W. Ablation of all synaptobrevin vSNAREs blocks evoked but not spontaneous neurotransmitter release at neuromuscular synapses. J Neurosci. 2019;: pubmed publisher
Hambleton E, Jones V, Maegele I, Kvaskoff D, Sachsenheimer T, Guse A. Sterol transfer by atypical cholesterol-binding NPC2 proteins in coral-algal symbiosis. elife. 2019;8: pubmed publisher
Wang C, Ma S, Bi S, Su L, Huang S, Miao J, et al. Enhancing autophagy protects platelets in immune thrombocytopenia patients. Ann Transl Med. 2019;7:134 pubmed publisher
Bauer C, Schneeberger P, Kortüm F, Altmuller J, Santos Simarro F, Baker L, et al. Gain-of-Function Mutations in KCNN3 Encoding the Small-Conductance Ca2+-Activated K+ Channel SK3 Cause Zimmermann-Laband Syndrome. Am J Hum Genet. 2019;104:1139-1157 pubmed publisher
Liu X, Wang M, Jiang T, He J, Fu X, Xu Y. IDO1 Maintains Pluripotency of Primed Human Embryonic Stem Cells by Promoting Glycolysis. Stem Cells. 2019;: pubmed publisher
Luo Y, Barrios Rodiles M, Gupta G, Zhang Y, Ogunjimi A, Bashkurov M, et al. Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility. Nat Commun. 2019;10:2356 pubmed publisher
Lin S, Liu Y. Mechanical Stretch Induces mTOR Recruitment and Activation at the Phosphatidic Acid-Enriched Macropinosome in Muscle Cell. Front Cell Dev Biol. 2019;7:78 pubmed publisher
Napolioni V, Pariano M, Borghi M, Oikonomou V, Galosi C, De Luca A, et al. Genetic Polymorphisms Affecting IDO1 or IDO2 Activity Differently Associate With Aspergillosis in Humans. Front Immunol. 2019;10:890 pubmed publisher
Iwai K, Nambu T, Dairiki R, Ohori M, Yu J, Burke K, et al. Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor. Sci Adv. 2019;5:eaav3660 pubmed publisher
Gambarotto D, Pennetier C, Ryniawec J, Buster D, Gogendeau D, Goupil A, et al. Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells. Dev Cell. 2019;: pubmed publisher
Lismont C, Koster J, Provost S, Baes M, Van Veldhoven P, Waterham H, et al. Deciphering the potential involvement of PXMP2 and PEX11B in hydrogen peroxide permeation across the peroxisomal membrane reveals a role for PEX11B in protein sorting. Biochim Biophys Acta Biomembr. 2019;: pubmed publisher
Lichtig H, Cohen Y, Bin Nun N, Golubkov V, Frank D. PTK7 proteolytic fragment proteins function during early Xenopus development. Dev Biol. 2019;: pubmed publisher
Hayashishita M, Kawahara H, Yokota N. BAG6 deficiency induces mis-distribution of mitochondrial clusters under depolarization. FEBS Open Bio. 2019;9:1281-1291 pubmed publisher
Zhao Y, Zhong S, Zhang S, Bi J, Xiao Z, Wang S, et al. UBN2 promotes tumor progression via the Ras/MAPK pathway and predicts poor prognosis in colorectal cancer. Cancer Cell Int. 2019;19:126 pubmed publisher
Fouquerel E, Barnes R, Uttam S, Watkins S, Bruchez M, Opresko P. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Mol Cell. 2019;: pubmed publisher
Reyes Fermín L, Avila Rojas S, Aparicio Trejo O, Tapia E, Rivero I, Pedraza Chaverri J. The Protective Effect of Alpha-Mangostin against Cisplatin-Induced Cell Death in LLC-PK1 Cells is Associated to Mitochondrial Function Preservation. Antioxidants (Basel). 2019;8: pubmed publisher
Slobodnyuk K, Radic N, Ivanova S, Lladó A, Trempolec N, Zorzano A, et al. Autophagy-induced senescence is regulated by p38α signaling. Cell Death Dis. 2019;10:376 pubmed publisher
Che L, Yang X, Ge C, El Amouri S, Wang Q, Pan D, et al. Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis. PLoS ONE. 2019;14:e0216553 pubmed publisher
Gravotta D, Perez Bay A, Jonker C, Zager P, Benedicto I, Schreiner R, et al. Clathrin and clathrin adaptor AP-1 control apical trafficking of megalin in the biosynthetic and recycling routes. Mol Biol Cell. 2019;30:1716-1728 pubmed publisher
Strutt H, Gamage J, Strutt D. Reciprocal action of Casein Kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation. elife. 2019;8: pubmed publisher
Boeckel S, Hrabalkova L, Baker T, MacPherson H, Frew L, Boyle A, et al. Cathelicidins and the Onset of Labour. Sci Rep. 2019;9:7356 pubmed publisher
Nakajima Y, Lee Z, McKinney S, Swanson S, Florens L, Gibson M. Junctional tumor suppressors interact with 14-3-3 proteins to control planar spindle alignment. J Cell Biol. 2019;218:1824-1838 pubmed publisher
Zdankowski P, McGloin D, Swedlow J. Full volume super-resolution imaging of thick mitotic spindle using 3D AO STED microscope. Biomed Opt Express. 2019;10:1999-2009 pubmed publisher
Giriwono P, Shirakawa H, Ohsaki Y, Sato S, Aoyama Y, Ho H, et al. Geranylgeraniol Suppresses the Expression of IRAK1 and TRAF6 to Inhibit NFκB Activation in Lipopolysaccharide-Induced Inflammatory Responses in Human Macrophage-Like Cells. Int J Mol Sci. 2019;20: pubmed publisher
Kurolap A, Eshach Adiv O, Konnikova L, Werner L, Gonzaga Jauregui C, Steinberg M, et al. A Unique Presentation of Infantile-Onset Colitis and Eosinophilic Disease without Recurrent Infections Resulting from a Novel Homozygous CARMIL2 Variant. J Clin Immunol. 2019;39:430-439 pubmed publisher
Xu M, Wang F, Li G, Wang X, Fang X, Jin H, et al. MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC. Mol Cancer. 2019;18:93 pubmed publisher
Mazloomian A, Araki S, Ohori M, El Naggar A, Yap D, Bashashati A, et al. Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation. Commun Biol. 2019;2:165 pubmed publisher
Xiao Z, Sperl B, Gartner S, Nedelko T, Stacher Priehse E, Ullrich A, et al. Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach. Oncotarget. 2019;10:2546-2560 pubmed publisher
Zhaojie L, Yuchen L, Miao C, Yacun C, Shayi W, Anbang H, et al. Gelsolin-like actin-capping protein has prognostic value and promotes tumorigenesis and epithelial-mesenchymal transition via the Hippo signaling pathway in human bladder cancer. Ther Adv Med Oncol. 2019;11:1758835919841235 pubmed publisher
Hamon A, García García D, Ail D, Bitard J, Chesneau A, Dalkara D, et al. Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina. Cell Rep. 2019;27:1712-1725.e6 pubmed publisher
Felipe Abrio B, Verdugo Sivianes E, Carnero A. c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer. Mol Oncol. 2019;: pubmed publisher
Vezzoli E, Caron I, Talpo F, Besusso D, Conforti P, Battaglia E, et al. Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease. J Clin Invest. 2019;130:2390-2403 pubmed publisher
Shariati S, Domínguez A, Xie S, Wernig M, Qi L, Skotheim J. Reversible Disruption of Specific Transcription Factor-DNA Interactions Using CRISPR/Cas9. Mol Cell. 2019;74:622-633.e4 pubmed publisher
Luo Q, Xiao Y, Alex A, Cummins T, Bhatwadekar A. The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1. Invest Ophthalmol Vis Sci. 2019;60:1928-1936 pubmed publisher
Tufi R, Gleeson T, von Stockum S, Hewitt V, Lee J, Terriente Félix A, et al. Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo. Cell Rep. 2019;27:1541-1550.e5 pubmed publisher
Lee S, Kieu C, Martin C, Han J, Chen W, Kim J, et al. NFATc3 plays an oncogenic role in oral/oropharyngeal squamous cell carcinomas by promoting cancer stemness via expression of OCT4. Oncotarget. 2019;10:2306-2319 pubmed publisher
Goto T, Kanda K, Nishikata T. Non-centrosomal microtubule structures regulated by egg activation signaling contribute to cytoplasmic and cortical reorganization in the ascidian egg. Dev Biol. 2019;448:161-172 pubmed publisher
Xiao C, Qiu S, Li X, Luo D, Liu G. EDTP/MTMR14: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates. Neurosci Lett. 2019;705:151-158 pubmed publisher
Texada M, Jørgensen A, Christensen C, Koyama T, Malita A, Smith D, et al. A fat-tissue sensor couples growth to oxygen availability by remotely controlling insulin secretion. Nat Commun. 2019;10:1955 pubmed publisher
Moncho Amor V, Pintado Berninches L, Ibanez de Caceres I, Martín Villar E, Quintanilla M, Chakravarty P, et al. Role of Dusp6 Phosphatase as a Tumor Suppressor in Non-Small Cell Lung Cancer. Int J Mol Sci. 2019;20: pubmed publisher
Gui Y, Lu Q, Gu M, Wang M, Liang Y, Zhu X, et al. Fibroblast mTOR/PPARγ/HGF axis protects against tubular cell death and acute kidney injury. Cell Death Differ. 2019;: pubmed publisher
Good A, Cannon C, Haemmerle M, Yang J, Stanescu D, Doliba N, et al. JUND regulates pancreatic β cell survival during metabolic stress. Mol Metab. 2019;25:95-106 pubmed publisher
Parker S, Krantz J, Kwak E, Barker N, Deer C, Lee N, et al. Insulin Induces Microtubule Stabilization and Regulates the Microtubule Plus-End Tracking Protein Network in Adipocytes. Mol Cell Proteomics. 2019;: pubmed publisher
Farina F, Ramkumar N, Brown L, Samandar Eweis D, Anstatt J, WARING T, et al. Local actin nucleation tunes centrosomal microtubule nucleation during passage through mitosis. EMBO J. 2019;38: pubmed publisher
Wu Z, Qiu M, Guo Y, Zhao J, Liu Z, Wang H, et al. OTU deubiquitinase 4 is silenced and radiosensitizes non-small cell lung cancer cells via inhibiting DNA repair. Cancer Cell Int. 2019;19:99 pubmed publisher
Emanuelli A, Manikoth Ayyathan D, Koganti P, Shah P, Apel Sarid L, Paolini B, et al. Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer. Cancers (Basel). 2019;11: pubmed publisher
Siddiqi F, Menzies F, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, et al. Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing. Nat Commun. 2019;10:1817 pubmed publisher
Huang X, Xue H, Ma J, Zhang Y, Zhang J, Liu Y, et al. Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β-catenin activity. J Cell Mol Med. 2019;23:4443-4453 pubmed publisher
Marcello E, Musardo S, Vandermeulen L, Pelucchi S, Gardoni F, Santo N, et al. Amyloid-β Oligomers Regulate ADAM10 Synaptic Localization Through Aberrant Plasticity Phenomena. Mol Neurobiol. 2019;: pubmed publisher
Tsai J, Hsu W, Liu J, Chang C, Tang T. CEP120 interacts with C2CD3 and Talpid3 and is required for centriole appendage assembly and ciliogenesis. Sci Rep. 2019;9:6037 pubmed publisher
Lau L, Porciuncula A, Yu A, Iwakura Y, David G. Uncoupling the Senescence-Associated Secretory Phenotype from Cell Cycle Exit via Interleukin-1 Inactivation Unveils Its Protumorigenic Role. Mol Cell Biol. 2019;39: pubmed publisher
Maslon M, Braunschweig U, Aitken S, Mann A, Kilanowski F, Hunter C, et al. A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes. EMBO J. 2019;38: pubmed publisher
Wang Y, Brady K, Caiello B, Ackerson S, Stewart J. Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association. Life Sci Alliance. 2019;2: pubmed publisher
Liao S, Kandasamy S, Zhu L, Fukunaga R. DEAD-box RNA helicase Belle post-transcriptionally promotes gene expression in an ATPase activity-dependent manner. RNA. 2019;: pubmed publisher
Xu W, Gulvady A, Goreczny G, Olson E, Turner C. Paxillin-dependent regulation of apical-basal polarity in mammary gland morphogenesis. Development. 2019;146: pubmed publisher
Scharner J, Qi S, Rigo F, Bennett C, Krainer A. Delivery of GalNAc-Conjugated Splice-Switching ASOs to Non-hepatic Cells through Ectopic Expression of Asialoglycoprotein Receptor. Mol Ther Nucleic Acids. 2019;16:313-325 pubmed publisher
Rogerson C, Britton E, Withey S, Hanley N, Ang Y, Sharrocks A. Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its pre-cancerous precursor state. Genome Res. 2019;: pubmed publisher
Chakraborty D, Felzen V, Hiebel C, Stürner E, Perumal N, Manicam C, et al. Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress. Redox Biol. 2019;24:101181 pubmed publisher
Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, et al. The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα. Nat Commun. 2019;10:1566 pubmed publisher
Dilsizoglu Senol A, Pepe A, Grudina C, Sassoon N, Reiko U, Bousset L, et al. Effect of tolytoxin on tunneling nanotube formation and function. Sci Rep. 2019;9:5741 pubmed publisher
Schwarzerová K, Bellinvia E, Martinek J, Sikorová L, Dostal V, Libusova L, et al. Tubulin is actively exported from the nucleus through the Exportin1/CRM1 pathway. Sci Rep. 2019;9:5725 pubmed publisher
Gan C, Sam K, Yee P, Zainal N, Lee B, Abdul Rahman Z, et al. IFITM3 knockdown reduces the expression of CCND1 and CDK4 and suppresses the growth of oral squamous cell carcinoma cells. Cell Oncol (Dordr). 2019;: pubmed publisher
Ho D, Lee H, Son I, Seol W. G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses. Anim Cells Syst (Seoul). 2019;23:106-111 pubmed publisher
Ravindran S, Nalavadi V, Muddashetty R. BDNF Induced Translation of Limk1 in Developing Neurons Regulates Dendrite Growth by Fine-Tuning Cofilin1 Activity. Front Mol Neurosci. 2019;12:64 pubmed publisher
Aparisi Rey A, Karaulanov E, Sharopov S, Arab K, Schäfer A, Gierl M, et al. Gadd45α modulates aversive learning through post-transcriptional regulation of memory-related mRNAs. EMBO Rep. 2019;20: pubmed publisher
Celaya A, Sanchez Perez I, Bermúdez Muñoz J, Rodriguez de la Rosa L, Pintado Berninches L, Perona R, et al. Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss. elife. 2019;8: pubmed publisher
Cho I, Hunter C, Ye S, Pongos A, Chan A. Combination of stem cell and gene therapy ameliorates symptoms in Huntington's disease mice. NPJ Regen Med. 2019;4:7 pubmed publisher
Peñalver González B, Vallejo Rodríguez J, Mentxaka G, Fullaondo A, Iglesias Ara A, Field S, et al. Golgi Oncoprotein GOLPH3 Gene Expression Is Regulated by Functional E2F and CREB/ATF Promoter Elements. Genes (Basel). 2019;10: pubmed publisher
Zarei M, Pujol E, Quesada López T, Villarroya F, Barroso E, Vazquez S, et al. Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21. Br J Pharmacol. 2019;176:2292-2305 pubmed publisher
El Houjeiri L, Possik E, Vijayaraghavan T, Paquette M, Martina J, Kazan J, et al. The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance. Cell Rep. 2019;26:3613-3628.e6 pubmed publisher
Zinn A, Goicoechea S, Kreider Letterman G, Maity D, Awadia S, Cedeno Rosario L, et al. The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly. Sci Rep. 2019;9:5163 pubmed publisher
Tsalikis J, Abdel Nour M, Farahvash A, Sorbara M, Poon S, Philpott D, et al. Isoginkgetin, a Natural Biflavonoid Proteasome Inhibitor, Sensitizes Cancer Cells to Apoptosis via Disruption of Lysosomal Homeostasis and Impaired Protein Clearance. Mol Cell Biol. 2019;39: pubmed publisher
Uzair I, Conte Grand J, Flamini M, Sanchez A. Molecular Actions of Thyroid Hormone on Breast Cancer Cell Migration and Invasion via Cortactin/N-WASP. Front Endocrinol (Lausanne). 2019;10:139 pubmed publisher
Yamaguchi T, Hayashi M, Ida L, Yamamoto M, Lu C, Kajino T, et al. ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma. Oncogene. 2019;: pubmed publisher
Akande O, Damle P, Pop M, Sherman N, Szomju B, Litovchick L, et al. DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination. Cell Rep. 2019;26:3323-3335.e4 pubmed publisher
Aziz K, Limzerwala J, Sturmlechner I, Hurley E, Zhang C, Jeganathan K, et al. Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice. Gastroenterology. 2019;: pubmed publisher
Wiegand C, Abel M, Hipler U, Elsner P. Effect of non-adhering dressings on promotion of fibroblast proliferation and wound healing in vitro. Sci Rep. 2019;9:4320 pubmed publisher
Li K, Qiu C, Sun P, Liu D, Wu T, Wang K, et al. Ets1-Mediated Acetylation of FoxO1 Is Critical for Gluconeogenesis Regulation during Feed-Fast Cycles. Cell Rep. 2019;26:2998-3010.e5 pubmed publisher
Hong A, Tseng Y, Wala J, Kim W, Kynnap B, Doshi M, et al. Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition. elife. 2019;8: pubmed publisher
Crerar H, Scott Solomon E, Bodkin Clarke C, Andreassi C, Hazbon M, Logie E, et al. Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019;102:553-563.e8 pubmed publisher
Ichisima J, Suzuki N, Samata B, Awaya T, Takahashi J, Hagiwara M, et al. Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model. J Hum Genet. 2019;64:445-458 pubmed publisher
Zhang D, Liu X, Xu X, Xu J, Yi Z, Shan B, et al. HPCAL1 promotes glioblastoma proliferation via activation of Wnt/β-catenin signalling pathway. J Cell Mol Med. 2019;23:3108-3117 pubmed publisher
Böhme M, McCarthy A, Grasskamp A, Beuschel C, Goel P, Jusyte M, et al. Rapid active zone remodeling consolidates presynaptic potentiation. Nat Commun. 2019;10:1085 pubmed publisher
Gleason C, Oses Prieto J, Li K, Saha B, Situ G, Burlingame A, et al. Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt. J Cell Sci. 2019;132: pubmed publisher
Zhou R, Yang Y, Park S, Seo Y, Jung S, Kim K, et al. p300/CBP-associated factor promotes autophagic degradation of δ-catenin through acetylation and decreases prostate cancer tumorigenicity. Sci Rep. 2019;9:3351 pubmed publisher
Li L, Wu S, Yan M, Lian Q, Ge R, Cheng C. Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: An in vitro study. Asian J Androl. 2019;21:365-375 pubmed publisher
Mylavarapu S, Kumar H, Kumari S, Sravanthi L, Jain M, Basu A, et al. Activation of Epithelial-Mesenchymal Transition and Altered β-Catenin Signaling in a Novel Indian Colorectal Carcinoma Cell Line. Front Oncol. 2019;9:54 pubmed publisher
Pudełek M, Catapano J, Kochanowski P, Mrowiec K, Janik Olchawa N, Czyz J, et al. Therapeutic potential of monoterpene α-thujone, the main compound of Thuja occidentalis L. essential oil, against malignant glioblastoma multiforme cells in vitro. Fitoterapia. 2019;134:172-181 pubmed publisher
Choi S, Martínez T, Kim S, Donaldson C, Shokhirev M, Saghatelian A, et al. CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability. Genes Dev. 2019;33:418-435 pubmed publisher
Chen S, Yue J, Zhang J, Jiang M, Hu T, Leng W, et al. Continuous exposure of isoprenaline inhibits myoblast differentiation and fusion through PKA/ERK1/2-FOXO1 signaling pathway. Stem Cell Res Ther. 2019;10:70 pubmed publisher
Duciel L, Anezo O, Mandal K, Laurent C, Planque N, Coquelle F, et al. Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2. Sci Rep. 2019;9:2990 pubmed publisher
Antas P, Novellasdemunt L, Kucharska A, Massie I, Carvalho J, Oukrif D, et al. SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization. Cell Rep. 2019;26:2266-2273.e4 pubmed publisher
Li L, Mao B, Yan M, Wu S, Ge R, Lian Q, et al. Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization. Cell Death Dis. 2019;10:194 pubmed publisher
Baron D, Matheny T, Lin Y, Leszyk J, Kenna K, Gall K, et al. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Hum Mol Genet. 2019;: pubmed publisher
Grigelioniene G, Suzuki H, Taylan F, Mirzamohammadi F, Borochowitz Z, Ayturk U, et al. Gain-of-function mutation of microRNA-140 in human skeletal dysplasia. Nat Med. 2019;25:583-590 pubmed publisher
Senturk M, Lin G, Zuo Z, Mao D, Watson E, Mikos A, et al. Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Nat Cell Biol. 2019;21:384-396 pubmed publisher
Carim S, Ben El Kadhi K, Yan G, Sweeney S, Hickson G, Carreno S, et al. IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis. Curr Biol. 2019;: pubmed publisher
Zhao M, Xie J, Shu W, Wang H, Bi J, Jiang W, et al. MiR-15b and miR-322 inhibit SETD3 expression to repress muscle cell differentiation. Cell Death Dis. 2019;10:183 pubmed publisher
Gültekin Y, Steller H. Axin proteolysis by Iduna is required for the regulation of stem cell proliferation and intestinal homeostasis in Drosophila. Development. 2019;146: pubmed publisher
Liao M, Liao W, Xu N, Li B, Liu F, Zhang S, et al. LncRNA EPB41L4A-AS1 regulates glycolysis and glutaminolysis by mediating nucleolar translocation of HDAC2. EBioMedicine. 2019;41:200-213 pubmed publisher
Mirkovic M, Guilgur L, Tavares A, Passagem Santos D, Oliveira R. Induced aneuploidy in neural stem cells triggers a delayed stress response and impairs adult life span in flies. PLoS Biol. 2019;17:e3000016 pubmed publisher
Legge D, Shephard A, Collard T, Greenhough A, Chambers A, Clarkson R, et al. BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells. Dis Model Mech. 2019;12: pubmed publisher
Lampi Y, Van Looveren D, Vranckx L, Thiry I, Bornschein S, Debyser Z, et al. Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection. Sci Rep. 2019;9:2389 pubmed publisher
Izumi H, Li Y, Shibaki M, Mori D, Yasunami M, Sato S, et al. Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region. Sci Rep. 2019;9:2236 pubmed publisher
Shi P, Wang Y, Huang Y, Zhang C, Li Y, Liu Y, et al. Arp2/3-branched actin regulates microtubule acetylation level and affects mitochondrial distribution. J Cell Sci. 2019;: pubmed publisher
Felipe Abrio B, Verdugo Sivianes E, Saez C, Carnero A. Loss of MYBBP1A Induces Cancer Stem Cell Activity in Renal Cancer. Cancers (Basel). 2019;11: pubmed publisher
Kaya Aksoy E, Cingöz A, Senbabaoglu F, Seker F, Sur Erdem I, Kayabolen A, et al. The pro-apoptotic Bcl-2 family member Harakiri (HRK) induces cell death in glioblastoma multiforme. Cell Death Discov. 2019;5:64 pubmed publisher
Ibrahim D, Ko J, Iwata W, Okumichi H, Kiuchi Y. An in vitro study of scarring formation mediated by human Tenon fibroblasts: Effect of Y-27632, a Rho kinase inhibitor. Cell Biochem Funct. 2019;37:113-124 pubmed publisher
Di Emidio G, Santini S, D Alessandro A, Vetuschi A, Sferra R, Artini P, et al. SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary. Biochim Biophys Acta Mol Basis Dis. 2019;1865:1389-1401 pubmed publisher
Estañ M, Fernández Núñez E, Zaki M, Esteban M, Donkervoort S, Hawkins C, et al. Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy. Nat Commun. 2019;10:797 pubmed publisher
Maio N, Kim K, Holmes Hampton G, Singh A, Rouault T. Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. Haematologica. 2019;: pubmed publisher
Hepburn A, Steele R, Veeratterapillay R, Wilson L, Kounatidou E, Barnard A, et al. The induction of core pluripotency master regulators in cancers defines poor clinical outcomes and treatment resistance. Oncogene. 2019;38:4412-4424 pubmed publisher
Araki K, Kawauchi K, Sugimoto W, Tsuda D, Oda H, Yoshida R, et al. Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells. Commun Biol. 2019;2:3 pubmed publisher
Takenaka N, Araki N, Satoh T. Involvement of the protein kinase Akt2 in insulin-stimulated Rac1 activation leading to glucose uptake in mouse skeletal muscle. PLoS ONE. 2019;14:e0212219 pubmed publisher
Hu J, Lessard C, Longstaff C, O Brien M, Palmer K, Reinholdt L, et al. ENU-induced mutant allele of Dnah1, ferf1, causes abnormal sperm behavior and fertilization failure in mice. Mol Reprod Dev. 2019;86:416-425 pubmed publisher
Stefanski A, Martinez N, Peterson L, Callahan T, Treacy E, Luck M, et al. Murine trophoblast-derived and pregnancy-associated exosome-enriched extracellular vesicle microRNAs: Implications for placenta driven effects on maternal physiology. PLoS ONE. 2019;14:e0210675 pubmed publisher
Pierce E, Graham B, Stiff M, Osborne J, Haigler C. Cultures of Gossypium barbadense cotton ovules offer insights into the microtubule-mediated control of fiber cell expansion. Planta. 2019;249:1551-1563 pubmed publisher
Wehrle A, Witkos T, Unger S, Schneider J, Follit J, Hermann J, et al. Hypomorphic mutations of TRIP11 cause odontochondrodysplasia. JCI Insight. 2019;4: pubmed publisher
Sanchez Ruderisch H, Queirós A, Fliegner D, Eschen C, Kararigas G, Regitz Zagrosek V. Sex-specific regulation of cardiac microRNAs targeting mitochondrial proteins in pressure overload. Biol Sex Differ. 2019;10:8 pubmed publisher
Ho D, Seol W, Son I. Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein. Cell Cycle. 2019;18:467-475 pubmed publisher
Sanidas I, Morris R, Fella K, Rumde P, Boukhali M, Tai E, et al. A Code of Mono-phosphorylation Modulates the Function of RB. Mol Cell. 2019;73:985-1000.e6 pubmed publisher
Vacca F, Vossio S, Mercier V, Moreau D, Johnson S, Scott C, et al. Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells. J Lipid Res. 2019;60:832-843 pubmed publisher
Villafañez F, García I, Carbajosa S, Pansa M, Mansilla S, Llorens M, et al. AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress. Oncogene. 2019;38:4310-4324 pubmed publisher
Rivero S, Gómez Marín E, Guerrero Martínez J, García Martínez J, Reyes J. TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells. Cell Death Dis. 2019;10:95 pubmed publisher
de Pins B, Cifuentes Diaz C, Farah A, López Molina L, Montalban E, Sancho Balsells A, et al. Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease. J Neurosci. 2019;39:2441-2458 pubmed publisher
Kern S, Truebenbach I, Höhn M, Gorges J, Kazmaier U, Zahler S, et al. Combined antitumoral effects of pretubulysin and methotrexate. Pharmacol Res Perspect. 2019;7:e00460 pubmed publisher
Tabariès S, McNulty A, Ouellet V, Annis M, Dessureault M, Vinette M, et al. Afadin cooperates with Claudin-2 to promote breast cancer metastasis. Genes Dev. 2019;33:180-193 pubmed publisher
Stewart M, Lau P, Banks G, Bains R, Castroflorio E, Oliver P, et al. Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities. Dis Model Mech. 2019;12: pubmed publisher
Wu Z, Qiu M, Mi Z, Meng M, Guo Y, Jiang X, et al. WT1-interacting protein inhibits cell proliferation and tumorigenicity in non-small-cell lung cancer via the AKT/FOXO1 axis. Mol Oncol. 2019;13:1059-1074 pubmed publisher
Isgrig K, McDougald D, Zhu J, Wang H, Bennett J, Chien W. AAV2.7m8 is a powerful viral vector for inner ear gene therapy. Nat Commun. 2019;10:427 pubmed publisher
Abe Y, Suzuki Y, Kawamura K, Tanaka N. MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex. Commun Biol. 2019;2:23 pubmed publisher
Rabouw H, Langereis M, Anand A, Visser L, de Groot R, Walter P, et al. Small molecule ISRIB suppresses the integrated stress response within a defined window of activation. Proc Natl Acad Sci U S A. 2019;116:2097-2102 pubmed publisher
Dwivedi D, Kumari A, Rathi S, Mylavarapu S, Sharma M. The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis. J Cell Biol. 2019;: pubmed publisher
Wen S, Lima L, Lobb R, Norris E, Hastie M, Krumeich S, et al. Breast Cancer-Derived Exosomes Reflect the Cell-of-Origin Phenotype. Proteomics. 2019;19:e1800180 pubmed publisher
Di Giacomo S, Briz O, Monte M, Sanchez Vicente L, Abete L, Lozano E, et al. Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps. Arch Toxicol. 2019;93:623-634 pubmed publisher
Nagano T, Yamao S, Terachi A, Yarimizu H, Itoh H, Katasho R, et al. d-amino acid oxidase promotes cellular senescence via the production of reactive oxygen species. Life Sci Alliance. 2019;2: pubmed publisher
Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed publisher
Lodyga M, Cambridge E, Karvonen H, Pakshir P, Wu B, Boo S, et al. Cadherin-11-mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β. Sci Signal. 2019;12: pubmed publisher
Jiménez López J, El Hammadi M, Ortiz R, Cayero Otero M, Cabeza L, Perazzoli G, et al. A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer. Pharmacol Res. 2019;141:451-465 pubmed publisher
Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers T, et al. Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells. Haematologica. 2019;: pubmed publisher
Garrido Rodríguez M, Ortea I, Calzado M, Munoz E, Garcia V. SWATH proteomic profiling of prostate cancer cells identifies NUSAP1 as a potential molecular target for Galiellalactone. J Proteomics. 2019;193:217-229 pubmed publisher
Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, et al. The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer. Cell Rep. 2019;26:415-428.e5 pubmed publisher
Picco M, Castro M, Quezada M, Barbero G, Villanueva M, Fernández N, et al. STAT3 enhances the constitutive activity of AGC kinases in melanoma by transactivating PDK1. Cell Biosci. 2019;9:3 pubmed publisher
Morgan M, Kabayama Y, Much C, Ivanova I, Di Giacomo M, Auchynnikava T, et al. A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis. Cell Res. 2019;29:221-232 pubmed publisher
Del Olmo T, Lauzier A, Normandin C, Larcher R, Lecours M, Jean D, et al. APEX2-mediated RAB proximity labeling identifies a role for RAB21 in clathrin-independent cargo sorting. EMBO Rep. 2019;20: pubmed publisher
Tona R, Chen W, Nakano Y, Reyes L, Petralia R, Wang Y, et al. The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy. Hum Mol Genet. 2019;28:1530-1547 pubmed publisher
Broekema M, Massink M, Donato C, de Ligt J, Schaarschmidt J, Borgman A, et al. Natural helix 9 mutants of PPARγ differently affect its transcriptional activity. Mol Metab. 2019;20:115-127 pubmed publisher
Porokuokka L, Virtanen H, Lindén J, Sidorova Y, Danilova T, Lindahl M, et al. Gfra1 Underexpression Causes Hirschsprung's Disease and Associated Enterocolitis in Mice. Cell Mol Gastroenterol Hepatol. 2019;7:655-678 pubmed publisher
Yang X, Lou Y, Wang M, Liu C, Liu Y, Huang W. miR‑675 promotes colorectal cancer cell growth dependent on tumor suppressor DMTF1. Mol Med Rep. 2019;19:1481-1490 pubmed publisher
Cejas R, Lorenz V, Garay Y, Irazoqui F. Biosynthesis of O-N-acetylgalactosamine glycans in the human cell nucleus. J Biol Chem. 2019;294:2997-3011 pubmed publisher
Tiedemann K, Sadvakassova G, Mikolajewicz N, Juhas M, Sabirova Z, Tabariès S, et al. Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis. Transl Oncol. 2019;12:462-474 pubmed publisher
Zhao Z, Kesti T, Uğurlu H, Baur A, Fagerlund R, Saksela K. Tyrosine phosphorylation directs TACE into extracellular vesicles via unconventional secretion. Traffic. 2019;20:202-212 pubmed publisher
Todaro F, Campolo F, Barrios F, Pellegrini M, Di Cesare S, Tessarollo L, et al. Regulation of Kit Expression in Early Mouse Embryos and ES Cells. Stem Cells. 2019;37:332-344 pubmed publisher
Yin W, Satkunendran T, Mo R, Morrissy S, Zhang X, Huang E, et al. Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma. Dev Cell. 2019;48:167-183.e5 pubmed publisher
Le Dily F, Vidal E, Cuartero Y, Quilez J, Nacht A, Vicent G, et al. Hormone-control regions mediate steroid receptor-dependent genome organization. Genome Res. 2019;29:29-39 pubmed publisher
Lafarga V, Sung H, Haneke K, Roessig L, Pauleau A, Bruer M, et al. TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress. EMBO Rep. 2019;20: pubmed publisher
Packer L, Stehbens S, Bonazzi V, Gunter J, Ju R, Ward M, et al. Bcl-2 inhibitors enhance FGFR inhibitor-induced mitochondrial-dependent cell death in FGFR2-mutant endometrial cancer. Mol Oncol. 2019;13:738-756 pubmed publisher
Shirai Y, Mizutani A, Nishijima S, Horie M, Kikuguchi C, Elisseeva O, et al. CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development. Oncogene. 2019;38:2580-2594 pubmed publisher
Khan M, Muzumdar D, Shiras A. Attenuation of Tumor Suppressive Function of FBXO16 Ubiquitin Ligase Activates Wnt Signaling In Glioblastoma. Neoplasia. 2019;21:106-116 pubmed publisher
Gold D, Katsuki T, Li Y, Yan X, Regulski M, Ibberson D, et al. The genome of the jellyfish Aurelia and the evolution of animal complexity. Nat Ecol Evol. 2019;3:96-104 pubmed publisher
Phan A, Thomas C, Chakraborty M, Berry J, Kamasawa N, Davis R. Stromalin Constrains Memory Acquisition by Developmentally Limiting Synaptic Vesicle Pool Size. Neuron. 2019;101:103-118.e5 pubmed publisher
Sharma P, Lioutas A, Fernandez Fuentes N, Quilez J, Carbonell Caballero J, Wright R, et al. Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription. Mol Cell. 2019;73:84-96.e7 pubmed publisher
Vigolo E, Markó L, Hinze C, Muller D, Schmidt Ullrich R, Schmidt Ott K. Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury. Kidney Int. 2019;95:108-122 pubmed publisher
Hu L, Huang H, Hei M, Yang Y, Li S, Liu Y, et al. Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment. Nucleic Acids Res. 2019;47:468-479 pubmed publisher
Higashi T, Stephenson R, Miller A. Comprehensive analysis of formin localization in Xenopus epithelial cells. Mol Biol Cell. 2019;30:82-95 pubmed publisher
Tan Z, Chan Y, Chua Y, Rutledge S, Pavelka N, Cimini D, et al. Environmental stresses induce karyotypic instability in colorectal cancer cells. Mol Biol Cell. 2019;30:42-55 pubmed publisher
Pillozzi S, Bernini A, Spiga O, Lelli B, Petroni G, Bracci L, et al. Peptides and small molecules blocking the CXCR4/CXCL12 axis overcome bone marrow‑induced chemoresistance in acute leukemias. Oncol Rep. 2019;41:312-324 pubmed publisher
Simhadri S, Vincelli G, Huo Y, Misenko S, Foo T, Ahlskog J, et al. PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response. Oncogene. 2019;38:1585-1596 pubmed publisher
Wood T, Barry J, Yang Z, Cepeda C, Levine M, Gray M. Mutant huntingtin reduction in astrocytes slows disease progression in the BACHD conditional Huntington's disease mouse model. Hum Mol Genet. 2019;28:487-500 pubmed publisher
Boyle A, Rinaldi S, Rossi A, Saunders P, Norman J. Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models. FASEB J. 2019;33:2743-2758 pubmed publisher
Broustas C, Hopkins K, Panigrahi S, Wang L, Virk R, Lieberman H. RAD9A promotes metastatic phenotypes through transcriptional regulation of anterior gradient 2 (AGR2). Carcinogenesis. 2019;40:164-172 pubmed publisher
Kikuchi K, Ihara D, Fukuchi M, Tanabe H, Ishibashi Y, Tsujii J, et al. Involvement of SRF coactivator MKL2 in BDNF-mediated activation of the synaptic activity-responsive element in the Arc gene. J Neurochem. 2019;148:204-218 pubmed publisher
Prasad H, Dang D, Kondapalli K, Natarajan N, Cebotaru V, Rao R. NHA2 promotes cyst development in an in vitro model of polycystic kidney disease. J Physiol. 2019;597:499-519 pubmed publisher
Arbel Rubinstein T, Shahmoon S, Zigmond E, Etan T, Merenbakh Lamin K, Pasmanik Chor M, et al. Klotho suppresses colorectal cancer through modulation of the unfolded protein response. Oncogene. 2019;38:794-807 pubmed publisher
Son S, Park S, Lee H, Siddiqi F, Lee J, Menzies F, et al. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Cell Metab. 2019;29:192-201.e7 pubmed publisher
Takeshima H, Horie M, Mikami Y, Makita K, Miyashita N, Matsuzaki H, et al. CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts. Allergol Int. 2019;68:101-109 pubmed publisher
Killackey S, Rahman M, Soares F, Zhang A, Abdel Nour M, Philpott D, et al. The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1. Mol Cell Biochem. 2019;453:187-196 pubmed publisher
Negoita F, Blomdahl J, Wasserstrom S, Winberg M, Osmark P, Larsson S, et al. PNPLA3 variant M148 causes resistance to starvation-mediated lipid droplet autophagy in human hepatocytes. J Cell Biochem. 2019;120:343-356 pubmed publisher
Peeters J, Picavet L, Coenen S, Mauthe M, Vervoort S, Mocholí E, et al. Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy. Autophagy. 2019;15:98-112 pubmed publisher
Yang V, Liu Y, Kim J, Shroyer K, Bialkowska A. Increased Genetic Instability and Accelerated Progression of Colitis-Associated Colorectal Cancer through Intestinal Epithelium-specific Deletion of Klf4. Mol Cancer Res. 2019;17:165-176 pubmed publisher
Sharma M, Sajikumar S. G9a/GLP Complex Acts as a Bidirectional Switch to Regulate Metabotropic Glutamate Receptor-Dependent Plasticity in Hippocampal CA1 Pyramidal Neurons. Cereb Cortex. 2019;29:2932-2946 pubmed publisher
Karalis T, Heldin P, Vynios D, Neill T, Buraschi S, Iozzo R, et al. Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors. Matrix Biol. 2019;78-79:118-138 pubmed publisher
Göktuna S. IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation. Turk J Biol. 2018;42:268-278 pubmed publisher
Webster K, Henke K, Ingalls D, Nahrin A, Harris M, Siegfried K. Cyclin-dependent kinase 21 is a novel regulator of proliferation and meiosis in the male germline of zebrafish. Reproduction. 2018;157:383-398 pubmed publisher
Hoppstädter J, Diesel B, Linnenberger R, Hachenthal N, Flamini S, Minet M, et al. Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages. Front Immunol. 2018;9:3111 pubmed publisher
Li Z, Zhang X, Guo Z, Zhong Y, Wang P, Li J, et al. SIRT6 Suppresses NFATc4 Expression and Activation in Cardiomyocyte Hypertrophy. Front Pharmacol. 2018;9:1519 pubmed publisher
Budka J, Ferris M, Capone M, Hollenhorst P. Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance. Genes Cancer. 2018;9:198-214 pubmed publisher
Tornillo G, Knowlson C, Kendrick H, Cooke J, Mirza H, Aurrekoetxea Rodríguez I, et al. Dual Mechanisms of LYN Kinase Dysregulation Drive Aggressive Behavior in Breast Cancer Cells. Cell Rep. 2018;25:3674-3692.e10 pubmed publisher
Ramani A, Mariappan A, Gottardo M, Mandad S, Urlaub H, Avidor Reiss T, et al. Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes. Cell Rep. 2018;25:3618-3630.e6 pubmed publisher
Singh R, Haka A, Bhardwaj P, Zha X, Maxfield F. Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and Catabolism. Arterioscler Thromb Vasc Biol. 2018;:ATVBAHA118312087 pubmed publisher
Antúnez Mojica M, Rojas Sepúlveda A, Mendieta Serrano M, González Maya L, Marquina S, Salas Vidal E, et al. Lignans from Bursera fagaroides Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos. Molecules. 2018;24: pubmed publisher
Guijarro T, Magro Lopez E, Manso J, Garcia Martinez R, Fernandez Aceñero M, Liste I, et al. Detrimental pro-senescence effects of vitamin D on lung fibrosis. Mol Med. 2018;24:64 pubmed publisher
Nagy S, Maurer G, Hentze J, Rose M, Werge T, Rewitz K. AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance. PLoS Genet. 2018;14:e1007623 pubmed publisher
John C, Grune J, Ott C, Nowotny K, Deubel S, Kühne A, et al. Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse. Front Endocrinol (Lausanne). 2018;9:732 pubmed publisher
Normand S, Waldschmitt N, Neerincx A, Martinez Torres R, Chauvin C, Couturier Maillard A, et al. Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens. Nat Commun. 2018;9:5338 pubmed publisher
Park S, Lim Y, Lee D, Elvira R, Lee J, Lee M, et al. Modulation of Protein Synthesis by eIF2α Phosphorylation Protects Cell from Heat Stress-Mediated Apoptosis. Cells. 2018;7: pubmed publisher
Menzies S, Volkmar N, van den Boomen D, Timms R, Dickson A, Nathan J, et al. The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1. elife. 2018;7: pubmed publisher
Perrucci G, Barbagallo V, Corlianò M, Tosi D, Santoro R, Nigro P, et al. Integrin ανβ5 in vitro inhibition limits pro-fibrotic response in cardiac fibroblasts of spontaneously hypertensive rats. J Transl Med. 2018;16:352 pubmed publisher
Relic B, Charlier E, Deroyer C, Malaise O, Crine Y, Neuville S, et al. Serum starvation raises turnover of phosphorylated p62/SQSTM1 (Serine 349), reveals expression of proteasome and N-glycanase1 interactive protein RAD23B and sensitizes human synovial fibroblasts to BAY 11-7085-induced cell death. Oncotarget. 2018;9:35830-35843 pubmed publisher
Varela Eirin M, Varela Vazquez A, Guitián Caamaño A, Paíno C, Mato V, Largo R, et al. Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis. Cell Death Dis. 2018;9:1166 pubmed publisher
Ciuba K, Hawkes W, Tojkander S, Kogan K, Engel U, Iskratsch T, et al. Calponin-3 is critical for coordinated contractility of actin stress fibers. Sci Rep. 2018;8:17670 pubmed publisher
Ikeuchi T, de Vega S, Forcinito P, Doyle A, Amaral J, Rodriguez I, et al. Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity. Sci Rep. 2018;8:17654 pubmed publisher
Ling H, Peng L, Wang J, Rahhal R, Seto E. Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication. Cell Rep. 2018;25:2851-2865.e3 pubmed publisher
Bainor A, Saini S, Calderon A, Casado Polanco R, Giner Ramirez B, Moncada C, et al. The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Cell Rep. 2018;25:2797-2807.e8 pubmed publisher
Solís C, Morales T. Lactation diminishes lesion-induced permeability of tracers into the brain. Brain Res Bull. 2018;144:92-100 pubmed publisher
Karole A, Chodisetty S, Ali A, Kumari N, Tyagi S. Novel sub-cellular localizations and intra-molecular interactions may define new functions of Mixed Lineage Leukemia protein. Cell Cycle. 2018;17:2684-2696 pubmed publisher
Doyle T, Moncorgé O, Bonaventure B, Pollpeter D, Lussignol M, Tauziet M, et al. The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry. Nat Microbiol. 2018;3:1369-1376 pubmed publisher
Marques M, Melo J, Cavadas B, Mendes N, Pereira L, Carneiro F, et al. Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells. Front Microbiol. 2018;9:2712 pubmed publisher
Zhu H, Zhang W, Zhao Y, Shu X, Wang W, Wang D, et al. GSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions. Mol Neurodegener. 2018;13:62 pubmed publisher
Marié I, Chang H, Levy D. HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies. J Exp Med. 2018;215:3194-3212 pubmed publisher
Jang J, Oh H, Nam D, Seol W, Seo M, Park S, et al. Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity. Anim Cells Syst (Seoul). 2018;22:273-280 pubmed publisher
Arnandis T, Monteiro P, Adams S, Bridgeman V, Rajeeve V, Gadaleta E, et al. Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion. Dev Cell. 2018;47:409-424.e9 pubmed publisher
Berto M, Jean V, Zwart W, Picard D. ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1. Life Sci Alliance. 2018;1:e201800055 pubmed publisher
Stoupa A, Adam F, Kariyawasam D, Strassel C, Gawade S, Szinnai G, et al. TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology. EMBO Mol Med. 2018;10: pubmed publisher
Artelt N, Siegerist F, Ritter A, Grisk O, Schlüter R, Endlich K, et al. Comparative Analysis of Podocyte Foot Process Morphology in Three Species by 3D Super-Resolution Microscopy. Front Med (Lausanne). 2018;5:292 pubmed publisher
Dogar A, Pauchard Batschulat R, Grisoni Neupert B, Richman L, Paillusson A, Pradervand S, et al. Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each. PLoS ONE. 2018;13:e0206823 pubmed publisher
Litvinchuk A, Wan Y, Swartzlander D, Chen F, Cole A, Propson N, et al. Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease. Neuron. 2018;100:1337-1353.e5 pubmed publisher
Park S, Mansur R, Lee Y, Lee J, Seo M, Choi A, et al. Liraglutide Activates mTORC1 Signaling and AMPA Receptors in Rat Hippocampal Neurons Under Toxic Conditions. Front Neurosci. 2018;12:756 pubmed publisher
Revinski D, Zaragosi L, Boutin C, Ruiz García S, Deprez M, Thomé V, et al. CDC20B is required for deuterosome-mediated centriole production in multiciliated cells. Nat Commun. 2018;9:4668 pubmed publisher
Xia Y, Huang N, Chen Z, Li F, Fan G, Ma D, et al. CCDC102B functions in centrosome linker assembly and centrosome cohesion. J Cell Sci. 2018;131: pubmed publisher
Lenis T, Hu J, Ng S, Jiang Z, Sarfare S, Lloyd M, et al. Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration. Proc Natl Acad Sci U S A. 2018;115:E11120-E11127 pubmed publisher
Hirota T, Blakeley P, Sangrithi M, Mahadevaiah S, Encheva V, Snijders A, et al. SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice. Dev Cell. 2018;47:645-659.e6 pubmed publisher
Cattin M, Deeke S, Dick S, Verret Borsos Z, Tennakoon G, Gupta R, et al. Expression of murine muscle-enriched A-type lamin-interacting protein (MLIP) is regulated by tissue-specific alternative transcription start sites. J Biol Chem. 2018;293:19761-19770 pubmed publisher
Lincoln F, Imig D, Boccellato C, Juric V, Noonan J, Kontermann R, et al. Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism. Cell Death Dis. 2018;9:1112 pubmed publisher
Li Q, Saito T, Martínez García M, Deshong A, Nadarajan S, Lawrence K, et al. The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans. PLoS Genet. 2018;14:e1007701 pubmed publisher
Witwicki R, Ekram M, Qiu X, Janiszewska M, Shu S, Kwon M, et al. TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer. Cell Rep. 2018;25:1255-1267.e5 pubmed publisher
Torgovnick A, Schiavi A, Shaik A, Kassahun H, Maglioni S, Rea S, et al. BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans. EMBO Rep. 2018;19: pubmed publisher
Rageot D, Bohnacker T, Melone A, Langlois J, Borsari C, Hillmann P, et al. Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders. J Med Chem. 2018;61:10084-10105 pubmed publisher
Yan C, Wang F, Peng Y, Williams C, Jenkins B, Wildonger J, et al. Microtubule Acetylation Is Required for Mechanosensation in Drosophila. Cell Rep. 2018;25:1051-1065.e6 pubmed publisher
Tang J, Shi N, Dong K, Brown S, Coleman A, Boegehold M, et al. Response Gene to Complement 32 Maintains Blood Pressure Homeostasis by Regulating α-Adrenergic Receptor Expression. Circ Res. 2018;123:1080-1090 pubmed publisher
Zhou Y, Xiao L, Tang S. Annexin A2 and FTH1 are potential biomarkers for lupus nephritis. Exp Ther Med. 2018;16:3766-3776 pubmed publisher
Piquet S, Le Parc F, Bai S, Chevallier O, Adam S, Polo S. The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage. Mol Cell. 2018;72:888-901.e7 pubmed publisher
Vezain M, Lecuyer M, Rubio M, Dupé V, Ratié L, David V, et al. A de novo variant in ADGRL2 suggests a novel mechanism underlying the previously undescribed association of extreme microcephaly with severely reduced sulcation and rhombencephalosynapsis. Acta Neuropathol Commun. 2018;6:109 pubmed publisher
Van Dijk J, Bompard G, Cau J, Kunishima S, Rabeharivelo G, Mateos Langerak J, et al. Microtubule polyglutamylation and acetylation drive microtubule dynamics critical for platelet formation. BMC Biol. 2018;16:116 pubmed publisher
Abreu C, Prakash R, Romanienko P, Roig I, Keeney S, Jasin M. Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination. Nat Commun. 2018;9:3961 pubmed publisher
Cortone G, Zheng G, Pensieri P, Chiappetta V, Tatè R, Malacaria E, et al. Interaction of the Warsaw breakage syndrome DNA helicase DDX11 with the replication fork-protection factor Timeless promotes sister chromatid cohesion. PLoS Genet. 2018;14:e1007622 pubmed publisher
Verde G, de Llobet L, Wright R, Quilez J, Peiro S, Le Dily F, et al. Unliganded Progesterone Receptor Governs Estrogen Receptor Gene Expression by Regulating DNA Methylation in Breast Cancer Cells. Cancers (Basel). 2018;10: pubmed publisher
Fets L, Driscoll P, Grimm F, Jain A, Nunes P, Gounis M, et al. MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG. Nat Chem Biol. 2018;14:1032-1042 pubmed publisher
Bono S, Dello Sbarba P, Lulli M. Sensitivity to imatinib of KCL22 chronic myeloid leukemia cell survival/growth and stem cell potential under glucose shortage. Data Brief. 2018;20:1901-1904 pubmed publisher
Soeda S, Yamada Nomoto K, Michiue T, Ohsugi M. RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability. Dev Cell. 2018;47:363-376.e5 pubmed publisher
Harms F, Kloth K, Bley A, Denecke J, Santer R, Lessel D, et al. Activating Mutations in PAK1, Encoding p21-Activated Kinase 1, Cause a Neurodevelopmental Disorder. Am J Hum Genet. 2018;103:579-591 pubmed publisher
Georgess D, Spuul P, Le Clainche C, Le Nihouannen D, Fremaux I, Dakhli T, et al. Anti-osteoclastic effects of C-glucosidic ellagitannins mediated by actin perturbation. Eur J Cell Biol. 2018;97:533-545 pubmed publisher
Zhu L, Kandasamy S, Liao S, Fukunaga R. LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes. Nat Commun. 2018;9:4031 pubmed publisher
Piwowarczyk K, Kwiecień E, Sośniak J, Zimoląg E, Guzik E, Sroka J, et al. Fenofibrate Interferes with the Diapedesis of Lung Adenocarcinoma Cells through the Interference with Cx43/EGF-Dependent Intercellular Signaling. Cancers (Basel). 2018;10: pubmed publisher
Salami J, Alabi S, Willard R, Vitale N, Wang J, Dong H, et al. Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance. Commun Biol. 2018;1:100 pubmed publisher
Baltussen L, Negraes P, Silvestre M, Claxton S, Moeskops M, Christodoulou E, et al. Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. EMBO J. 2018;37: pubmed publisher
Davies A, Itzhak D, Edgar J, Archuleta T, Hirst J, Jackson L, et al. AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A. Nat Commun. 2018;9:3958 pubmed publisher
Kistler K, Trcek T, Hurd T, Chen R, Liang F, Sall J, et al. Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells. elife. 2018;7: pubmed publisher
Saunders J, Hore Z, Gentry C, McMahon S, Denk F. Negative Evidence for a Functional Role of Neuronal DNMT3a in Persistent Pain. Front Mol Neurosci. 2018;11:332 pubmed publisher
Hou W, Cruz Cosme R, Wen F, Ahn J, Reeves I, Luo M, et al. Expression of Human Cytomegalovirus IE1 Leads to Accumulation of Mono-SUMOylated PML That Is Protected from Degradation by Herpes Simplex Virus 1 ICP0. J Virol. 2018;92: pubmed publisher
Monda J, Cheeseman I. Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymes. Open Biol. 2018;8: pubmed publisher
Boese C, Nye J, Buster D, McLamarrah T, Byrnes A, Slep K, et al. Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state. Mol Biol Cell. 2018;29:2874-2886 pubmed publisher
Taraborrelli L, Peltzer N, Montinaro A, Kupka S, Rieser E, Hartwig T, et al. LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L. Nat Commun. 2018;9:3910 pubmed publisher
Bacman S, Kauppila J, Pereira C, Nissanka N, Miranda M, Pinto M, et al. MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation. Nat Med. 2018;24:1696-1700 pubmed publisher
Fort L, Batista J, Thomason P, Spence H, Whitelaw J, Tweedy L, et al. Fam49/CYRI interacts with Rac1 and locally suppresses protrusions. Nat Cell Biol. 2018;20:1159-1171 pubmed publisher
Faktorová D, Bär A, Hashimi H, McKenney K, Horak A, Schnaufer A, et al. TbUTP10, a protein involved in early stages of pre-18S rRNA processing in Trypanosoma brucei. Mol Biochem Parasitol. 2018;225:84-93 pubmed publisher
Staufer O, Hernandez B J, Rustom A. Protease-resistant cell meshworks: An indication of membrane nanotube-based syncytia formation. Exp Cell Res. 2018;372:85-91 pubmed publisher
Arai T, Tanaka M, Goda N. HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver. Sci Rep. 2018;8:14230 pubmed publisher
Jiang C, Wang X, Li X, Inlora J, Wang T, Liu Q, et al. Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring. Cell. 2018;175:277-291.e31 pubmed publisher
Yoneyama Y, Inamitsu T, Chida K, Iemura S, Natsume T, Maeda T, et al. Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCF?-TRCP E3 Ubiquitin Ligase. iScience. 2018;5:1-18 pubmed publisher
Jin H, Choi S, Kang M, Yun S, Kwon D, Noh Y, et al. Salicylic acid-induced transcriptional reprogramming by the HAC-NPR1-TGA histone acetyltransferase complex in Arabidopsis. Nucleic Acids Res. 2018;46:11712-11725 pubmed publisher
Kučírková T, Stiborek M, Dúcka M, Navrátilová J, Bogdanović Pristov J, Popovic Bijelic A, et al. Anti-cancer effects of wedelolactone: interactions with copper and subcellular localization. Metallomics. 2018;10:1524-1531 pubmed publisher
Paez Mayorga J, Chen A, Kotla S, Tao Y, Abe R, He E, et al. Ponatinib Activates an Inflammatory Response in Endothelial Cells via ERK5 SUMOylation. Front Cardiovasc Med. 2018;5:125 pubmed publisher
Román García S, Merino Cortes S, Gardeta S, de Bruijn M, Hendriks R, Carrasco Y. Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation. Front Immunol. 2018;9:2027 pubmed publisher
Lu G, Weng S, Matyskiela M, Zheng X, Fang W, Wood S, et al. UBE2G1 governs the destruction of cereblon neomorphic substrates. elife. 2018;7: pubmed publisher
Morini R, Ferrara S, Perrucci F, Zambetti S, Pelucchi S, Marcello E, et al. Lack of the Actin Capping Protein, Eps8, Affects NMDA-Type Glutamate Receptor Function and Composition. Front Mol Neurosci. 2018;11:313 pubmed publisher
Ahmad M, Kroll T, Jakob J, Rauch A, Ploubidou A, Tuckermann J. Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators. Sci Rep. 2018;8:14045 pubmed publisher
Jimeno S, Camarillo R, Mejías Navarro F, Fernández Ávila M, Soria Bretones I, Prados Carvajal R, et al. The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures. Cell Rep. 2018;24:3262-3273.e4 pubmed publisher
Kim M, Park J, Lee E, Kim S, Shin S, Ahn J, et al. C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation. Oncol Rep. 2018;40:2977-2987 pubmed publisher
Gennaro V, Stanek T, Peck A, Sun Y, Wang F, Qie S, et al. Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells. Proc Natl Acad Sci U S A. 2018;115:E9298-E9307 pubmed publisher
Nakanishi N, Martindale M. CRISPR knockouts reveal an endogenous role for ancient neuropeptides in regulating developmental timing in a sea anemone. elife. 2018;7: pubmed publisher
Li J, Liu B, Song Y, Chen X. Cyclin A2 regulates symmetrical mitotic spindle formation and centrosome amplification in human colon cancer cells. Am J Transl Res. 2018;10:2669-2676 pubmed
Lopez Coral A, Striz A, Tuma P. A Serine/Threonine Kinase 16-Based Phospho-Proteomics Screen Identifies WD Repeat Protein-1 As A Regulator Of Constitutive Secretion. Sci Rep. 2018;8:13049 pubmed publisher
Møller A, Füchtbauer E, Brüel A, Andersen T, Borggaard X, Pavlos N, et al. Septins are critical regulators of osteoclastic bone resorption. Sci Rep. 2018;8:13016 pubmed publisher
Chen H, Fang Y, Wu J, Chen H, Zou Z, Zhang X, et al. RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD. Cell Death Dis. 2018;9:878 pubmed publisher
Tuo Q, Liuyang Z, Lei P, Yan X, Shentu Y, Liang J, et al. Zinc induces CDK5 activation and neuronal death through CDK5-Tyr15 phosphorylation in ischemic stroke. Cell Death Dis. 2018;9:870 pubmed publisher
Sasi N, Coquel F, Lin Y, Mackeigan J, Pasero P, Weinreich M. DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling. Neoplasia. 2018;20:985-995 pubmed publisher
Agarwal S, Smith K, Zhou Y, Suzuki A, McKenney R, Varma D. Cdt1 stabilizes kinetochore-microtubule attachments via an Aurora B kinase-dependent mechanism. J Cell Biol. 2018;217:3446-3463 pubmed publisher
Alpar L, Bergantiños C, Johnston L. Spatially Restricted Regulation of Spätzle/Toll Signaling during Cell Competition. Dev Cell. 2018;46:706-719.e5 pubmed publisher
Mehta M, Weinberg S, Steinert E, Chhiba K, Martinez C, Gao P, et al. Hexokinase 2 is dispensable for T cell-dependent immunity. Cancer Metab. 2018;6:10 pubmed publisher
Xu F, Takahashi H, Tanaka Y, Ichinose S, Niwa S, Wicklund M, et al. KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth. J Cell Biol. 2018;217:3480-3496 pubmed publisher
Silva R, Mirkovic M, Guilgur L, Rathore O, Martinho R, Oliveira R. Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion. Curr Biol. 2018;28:2837-2844.e3 pubmed publisher
den Hartigh L, Goodspeed L, Wang S, Kenerson H, Omer M, O Brien K, et al. Chronic oral rapamycin decreases adiposity, hepatic triglycerides and insulin resistance in male mice fed a diet high in sucrose and saturated fat. Exp Physiol. 2018;103:1469-1480 pubmed publisher
Heni H, Ebner J, Schmidt G, Aktories K, Orth J. Involvement of Osteocytes in the Action of Pasteurella multocida Toxin. Toxins (Basel). 2018;10: pubmed publisher
Aguirre Portolés C, Feliu J, Reglero G, Ramirez de Molina A. ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin-1-dependent invasiveness, and these effects can be ameliorated using the BET inhibitor apabetalone. Mol Oncol. 2018;12:1735-1752 pubmed publisher
Prinz E, Aviram S, Aronheim A. WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis. Mol Biol Cell. 2018;29:2470-2480 pubmed publisher
Takasugi N, Araya R, Kamikubo Y, Kaneshiro N, Imaoka R, Jin H, et al. TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes. PLoS ONE. 2018;13:e0200988 pubmed publisher
Parker A, Teo W, Pandzic E, Vicente J, McCarroll J, Wordeman L, et al. β-tubulin carboxy-terminal tails exhibit isotype-specific effects on microtubule dynamics in human gene-edited cells. Life Sci Alliance. 2018;1: pubmed publisher
Smith T, Van Slyke P, Jones N, Dumont D, McGlade C. Tie2 signalling through Erk1/2 regulates TLR4 driven inflammation. Cell Signal. 2018;51:211-221 pubmed publisher
Hiramuki Y, Tapscott S. Identification of SMCHD1 domains for nuclear localization, homo-dimerization, and protein cleavage. Skelet Muscle. 2018;8:24 pubmed publisher
Barry R, John S, Liccardi G, Tenev T, Jaco I, Chen C, et al. SUMO-mediated regulation of NLRP3 modulates inflammasome activity. Nat Commun. 2018;9:3001 pubmed publisher
de Carcer G, Venkateswaran S, Salgueiro L, El Bakkali A, Somogyi K, Rowald K, et al. Plk1 overexpression induces chromosomal instability and suppresses tumor development. Nat Commun. 2018;9:3012 pubmed publisher
Salinas Saavedra M, Rock A, Martindale M. Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm. elife. 2018;7: pubmed publisher
Jarak I, Almeida S, Carvalho R, Sousa M, Barros A, Alves M, et al. Senescence and declining reproductive potential: Insight into molecular mechanisms through testicular metabolomics. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3388-3396 pubmed publisher
Amini P, Stojkov D, Felser A, Jackson C, Courage C, Schaller A, et al. Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nat Commun. 2018;9:2958 pubmed publisher
Evangelista F, Maglott Roth A, Stierlé M, Brino L, Soutoglou E, Tora L. Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair. J Cell Biol. 2018;217:3382-3397 pubmed publisher
Falk N, Kessler K, Schramm S, Boldt K, Becirovic E, Michalakis S, et al. Functional analyses of Pericentrin and Syne-2 interaction in ciliogenesis. J Cell Sci. 2018;131: pubmed publisher
Valla M, Mjønes P, Engstrøm M, Ytterhus B, Bordin D, van Loon B, et al. Characterization of FGD5 Expression in Primary Breast Cancers and Lymph Node Metastases. J Histochem Cytochem. 2018;66:787-799 pubmed publisher
Siegerist F, Endlich K, Endlich N. Novel Microscopic Techniques for Podocyte Research. Front Endocrinol (Lausanne). 2018;9:379 pubmed publisher
Sulaiman A, McGarry S, Lam K, El Sahli S, Chambers J, Kaczmarek S, et al. Co-inhibition of mTORC1, HDAC and ESR1? retards the growth of triple-negative breast cancer and suppresses cancer stem cells. Cell Death Dis. 2018;9:815 pubmed publisher
Prudêncio P, Guilgur L, Sobral J, Becker J, Martinho R, Navarro Costa P. The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization. EMBO Rep. 2018;19: pubmed publisher
Aziz K, Sieben C, Jeganathan K, Hamada M, Davies B, Velasco R, et al. Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in Cep57 impairs tumor suppression. J Clin Invest. 2018;128:3517-3534 pubmed publisher
Devotta A, Hong C, Saint Jeannet J. Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner. elife. 2018;7: pubmed publisher
Wickert M, Hildick K, Baillie G, Jelinek R, Aparisi Rey A, Monory K, et al. The F238L Point Mutation in the Cannabinoid Type 1 Receptor Enhances Basal Endocytosis via Lipid Rafts. Front Mol Neurosci. 2018;11:230 pubmed publisher
Zhou L, Lim M, Kaur P, Saj A, Bortolamiol Becet D, Gopal V, et al. Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development. elife. 2018;7: pubmed publisher
Schiavon C, Griffin M, Pirozzi M, Parashuraman R, Zhou W, Jinnah H, et al. Compositional complexity of rods and rings. Mol Biol Cell. 2018;29:2303-2316 pubmed publisher
Ho D, Je A, Lee H, Son I, Kweon H, Kim H, et al. LRRK2 Kinase Activity Induces Mitochondrial Fission in Microglia via Drp1 and Modulates Neuroinflammation. Exp Neurobiol. 2018;27:171-180 pubmed publisher
Gambetta M, Furlong E. The Insulator Protein CTCF Is Required for Correct Hox Gene Expression, but Not for Embryonic Development in Drosophila. Genetics. 2018;210:129-136 pubmed publisher
Jang S, Zhang Y, Utani K, Fu H, Redon C, Marks A, et al. The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin. Nat Commun. 2018;9:2782 pubmed publisher
Yu B, Huo L, Liu Y, Deng P, Szymanski J, Li J, et al. PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ. Cell Stem Cell. 2018;23:193-209.e5 pubmed publisher
Akram S, Yang F, Li J, Adams G, Liu Y, Zhuang X, et al. LRIF1 interacts with HP1α to coordinate accurate chromosome segregation during mitosis. J Mol Cell Biol. 2018;10:527-538 pubmed publisher
Xu Y, Liu X, Zhang H, Zhu Z, Wu X, Wu X, et al. Overexpression of HES6 has prognostic value and promotes metastasis via the Wnt/β-catenin signaling pathway in colorectal cancer. Oncol Rep. 2018;40:1261-1274 pubmed publisher
Asada S, Goyama S, Inoue D, Shikata S, Takeda R, Fukushima T, et al. Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis. Nat Commun. 2018;9:2733 pubmed publisher
Pereira C, Bacman S, Arguello T, Zekonyte U, Williams S, Edgell D, et al. mitoTev-TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels. EMBO Mol Med. 2018;10: pubmed publisher
Zhang S, Li B, Tang W, Ni L, Ma H, Lu M, et al. Effects of connective tissue growth factor on prostate cancer bone metastasis and osteoblast differentiation. Oncol Lett. 2018;16:2305-2311 pubmed publisher
Yakoub A, Schulz R, Seiffert M, Sadek M. Autoantigen-Harboring Apoptotic Cells Hijack the Coinhibitory Pathway of T Cell Activation. Sci Rep. 2018;8:10533 pubmed publisher
Carvalhal S, Tavares A, Santos M, Mirkovic M, Oliveira R. A quantitative analysis of cohesin decay in mitotic fidelity. J Cell Biol. 2018;217:3343-3353 pubmed publisher
Simigdala N, Pancholi S, Ribas R, Folkerd E, Liccardi G, Nikitorowicz Buniak J, et al. Abiraterone shows alternate activity in models of endocrine resistant and sensitive disease. Br J Cancer. 2018;119:313-322 pubmed publisher
Blanch M, Dorca Arévalo J, Not A, Cases M, Gómez de Aranda I, Martínez Yélamos A, et al. The Cytotoxicity of Epsilon Toxin from Clostridium perfringens on Lymphocytes Is Mediated by MAL Protein Expression. Mol Cell Biol. 2018;38: pubmed publisher
Deshpande A, Collins K. Mechanisms of template handling and pseudoknot folding in human telomerase and their manipulation to expand the sequence repertoire of processive repeat synthesis. Nucleic Acids Res. 2018;46:7886-7901 pubmed publisher
Tovey C, Tubman C, Hamrud E, Zhu Z, Dyas A, Butterfield A, et al. ?-TuRC Heterogeneity Revealed by Analysis of Mozart1. Curr Biol. 2018;28:2314-2323.e6 pubmed publisher
Balta E, Wittmann M, Jung M, Sock E, Haeberle B, Heim B, et al. Phosphorylation Modulates the Subcellular Localization of SOX11. Front Mol Neurosci. 2018;11:211 pubmed publisher
Ahrens H, Huettemeister J, Schmidt M, Kaether C, von Maltzahn J. Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle. Skelet Muscle. 2018;8:20 pubmed publisher
Lee S, Lee E, Kim R, Kim J, Lee S, Park H, et al. Shank2 Deletion in Parvalbumin Neurons Leads to Moderate Hyperactivity, Enhanced Self-Grooming and Suppressed Seizure Susceptibility in Mice. Front Mol Neurosci. 2018;11:209 pubmed publisher
Lyu G, Guan Y, Zhang C, Zong L, Sun L, Huang X, et al. TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging. Nat Commun. 2018;9:2560 pubmed publisher
Lee E, Itan M, Jang J, Gu H, Rozenberg P, Mingler M, et al. Eosinophils support adipocyte maturation and promote glucose tolerance in obesity. Sci Rep. 2018;8:9894 pubmed publisher
Kim S, Hong M, Heo S, Park S, Kwon T, Sung Y, et al. Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous prote. Mol Carcinog. 2018;57:1492-1506 pubmed publisher
Schunselaar L, Monkhorst K, van der Noort V, Wijdeven R, Peters D, Zwart W, et al. Trophoblast Glycoprotein is Associated With a Favorable Outcome for Mesothelioma and a Target for Antibody Drug Conjugates. J Thorac Oncol. 2018;13:1577-1587 pubmed publisher
Wang Y, Shan B, Liang Y, Wei H, Yuan J. Parkin regulates NF-?B by mediating site-specific ubiquitination of RIPK1. Cell Death Dis. 2018;9:732 pubmed publisher
Torres Ayuso P, Sahoo S, Ashton G, An E, Simms N, Galvin M, et al. Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin. NPJ Genom Med. 2018;3:15 pubmed publisher
Bhargava R, Sandhu M, Muk S, Lee G, Vaidehi N, Stark J. C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains. Nat Commun. 2018;9:2484 pubmed publisher
Santhana Kumar K, Neve A, Guerreiro Stucklin A, Kuzan Fischer C, Rushing E, Taylor M, et al. TGF-? Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma. Cell Rep. 2018;23:3798-3812.e8 pubmed publisher
Sun Y, Wang P, Li H, Dai J. BMAL1 and CLOCK proteins in regulating UVB-induced apoptosis and DNA damage responses in human keratinocytes. J Cell Physiol. 2018;233:9563-9574 pubmed publisher
Maiti A, Myint W, Kanai T, Delviks Frankenberry K, Sierra Rodriguez C, Pathak V, et al. Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA. Nat Commun. 2018;9:2460 pubmed publisher
Sekine H, Okazaki K, Kato K, Alam M, Shima H, Katsuoka F, et al. O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1. Mol Cell Biol. 2018;38: pubmed publisher
Nielsen J, Nordgaard C, Tollenaere M, Bekker Jensen S. Osmotic Stress Blocks Mobility and Dynamic Regulation of Centriolar Satellites. Cells. 2018;7: pubmed publisher
Fang D, Gan H, Cheng L, Lee J, Zhou H, Sarkaria J, et al. H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers. elife. 2018;7: pubmed publisher
Stewart S, Ashkenazi A, Williamson A, Rubinsztein D, Moreau K. Transbilayer phospholipid movement facilitates the translocation of annexin across membranes. J Cell Sci. 2018;131: pubmed publisher
Hsu W, Wang W, Lin W, Huang Y, Lai C, Liao J, et al. Adducin-1 is essential for spindle pole integrity through its interaction with TPX2. EMBO Rep. 2018;19: pubmed publisher
Sikirzhytski V, Renda F, Tikhonenko I, Magidson V, McEwen B, Khodjakov A. Microtubules assemble near most kinetochores during early prometaphase in human cells. J Cell Biol. 2018;217:2647-2659 pubmed publisher
Manchanda K, Kolarova H, Kerkenpaß C, Mollenhauer M, Vitecek J, Rudolph V, et al. MPO (Myeloperoxidase) Reduces Endothelial Glycocalyx Thickness Dependent on Its Cationic Charge. Arterioscler Thromb Vasc Biol. 2018;: pubmed publisher
Freixo F, Martínez Delgado P, Manso Y, Sánchez Huertas C, Lacasa C, Soriano E, et al. NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization. Nat Commun. 2018;9:2330 pubmed publisher
Smigiel R, Landsberg G, Schilling M, Rydzanicz M, Pollak A, Walczak A, et al. Developmental epileptic encephalopathy with hypomyelination and brain atrophy associated with PTPN23 variants affecting the assembly of UsnRNPs. Eur J Hum Genet. 2018;26:1502-1511 pubmed publisher
Ganier O, Schnerch D, Nigg E. Structural centrosome aberrations sensitize polarized epithelia to basal cell extrusion. Open Biol. 2018;8: pubmed publisher
Yang Y, Chen J, Guo Z, Deng S, Du X, Zhu S, et al. Endophilin A1 Promotes Actin Polymerization in Dendritic Spines Required for Synaptic Potentiation. Front Mol Neurosci. 2018;11:177 pubmed publisher
Ahmed Y, Schleich S, Bohlen J, Mandel N, Simon B, Sinning I, et al. DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation. PLoS Biol. 2018;16:e2005160 pubmed publisher
Manhart A, Windner S, Baylies M, Mogilner A. Mechanical positioning of multiple nuclei in muscle cells. PLoS Comput Biol. 2018;14:e1006208 pubmed publisher
Hilbig D, Dietrich N, Wandel E, Gonsior S, Sittig D, Hamann J, et al. The Interaction of CD97/ADGRE5 With β-Catenin in Adherens Junctions Is Lost During Colorectal Carcinogenesis. Front Oncol. 2018;8:182 pubmed publisher
Shiimori M, Garrett S, Graveley B, Terns M. Cas4 Nucleases Define the PAM, Length, and Orientation of DNA Fragments Integrated at CRISPR Loci. Mol Cell. 2018;70:814-824.e6 pubmed publisher
Ribas R, Pancholi S, Rani A, Schuster E, Guest S, Nikitorowicz Buniak J, et al. Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer. Breast Cancer Res. 2018;20:44 pubmed publisher
Fawal M, Jungas T, Kischel A, Audouard C, Iacovoni J, Davy A. Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation. Cell Rep. 2018;23:2864-2873.e7 pubmed publisher
Tanaka K, Ikeda N, Miyashita K, Nuriya H, Hara T. DEAD box protein DDX1 promotes colorectal tumorigenesis through transcriptional activation of the LGR5 gene. Cancer Sci. 2018;109:2479-2489 pubmed publisher
Balogh K, Templeton D, Cross J. Macrophage Migration Inhibitory Factor protects cancer cells from immunogenic cell death and impairs anti-tumor immune responses. PLoS ONE. 2018;13:e0197702 pubmed publisher
Millership S, Da Silva Xavier G, Choudhury A, Bertazzo S, Chabosseau P, Pedroni S, et al. Neuronatin regulates pancreatic β cell insulin content and secretion. J Clin Invest. 2018;128:3369-3381 pubmed publisher
Sánchez Blázquez P, Cortés Montero E, Rodríguez Muñoz M, Garzón J. Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice. Int J Neuropsychopharmacol. 2018;21:938-948 pubmed publisher
Fernandez L, Sánchez Martínez R, Vargas T, Herranz J, Martin Hernandez R, Mendiola M, et al. The role of glycosyltransferase enzyme GCNT3 in colon and ovarian cancer prognosis and chemoresistance. Sci Rep. 2018;8:8485 pubmed publisher
Suwala A, Koch K, Rios D, Aretz P, Uhlmann C, Ogorek I, et al. Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro. Oncotarget. 2018;9:22703-22716 pubmed publisher
Wang W, Rein B, Zhang F, Tan T, Zhong P, Qin L, et al. Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome. J Neurosci. 2018;38:5939-5948 pubmed publisher
Serebrenik Y, Hellerschmied D, Toure M, Lopez Giraldez F, Brookner D, Crews C. Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response. Mol Biol Cell. 2018;29:1284-1298 pubmed publisher
Webber J, Zhang J, Massey A, Sanchez Luege N, Rebay I. Collaborative repressive action of the antagonistic ETS transcription factors Pointed and Yan fine-tunes gene expression to confer robustness in Drosophila. Development. 2018;145: pubmed publisher
Okumura M, Natsume T, Kanemaki M, Kiyomitsu T. Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble. elife. 2018;7: pubmed publisher
Lu Y, Fujioka H, Joshi D, Li Q, Sangwung P, Hsieh P, et al. Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge. Sci Rep. 2018;8:8251 pubmed publisher
Canovas B, Igea A, Sartori A, Gomis R, Paull T, Isoda M, et al. Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells. Cancer Cell. 2018;33:1094-1110.e8 pubmed publisher
Isono T, Chano T, Yoshida T, Kageyama S, Kawauchi A, Yonese J, et al. Abundance of TRAIL attenuated by HIF2α and c-FLIP affects malignancy in renal cell carcinomas. Oncotarget. 2018;9:23091-23101 pubmed publisher
Taga M, Mouton Liger F, Sadoune M, Gourmaud S, Norman J, Tible M, et al. PKR modulates abnormal brain signaling in experimental obesity. PLoS ONE. 2018;13:e0196983 pubmed publisher
Dudka D, Noatynska A, Smith C, Liaudet N, McAinsh A, Meraldi P. Complete microtubule-kinetochore occupancy favours the segregation of merotelic attachments. Nat Commun. 2018;9:2042 pubmed publisher
Garcia Lopez A, Tessaro F, Jonker H, Wacker A, Richter C, Comte A, et al. Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes. Nat Commun. 2018;9:2032 pubmed publisher
Lee C, Feke A, Li M, Adamchek C, Webb K, Pruneda Paz J, et al. Decoys Untangle Complicated Redundancy and Reveal Targets of Circadian Clock F-Box Proteins. Plant Physiol. 2018;177:1170-1186 pubmed publisher
Morelli G, Even A, Gladwyn Ng I, Le Bail R, Shilian M, Godin J, et al. p27Kip1 Modulates Axonal Transport by Regulating ?-Tubulin Acetyltransferase 1 Stability. Cell Rep. 2018;23:2429-2442 pubmed publisher
Krastev D, Pettitt S, Campbell J, Song F, Tanos B, Stoynov S, et al. Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets. Nat Commun. 2018;9:2016 pubmed publisher
Lacroix B, Letort G, Pitayu L, Sallé J, Stefanutti M, Maton G, et al. Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing. Dev Cell. 2018;45:496-511.e6 pubmed publisher
Shindo A, Audrey A, Takagishi M, Takahashi M, Wallingford J, Kinoshita M. Septin-dependent remodeling of cortical microtubule drives cell reshaping during epithelial wound healing. J Cell Sci. 2018;131: pubmed publisher
Chun S, Lee S, Flores Toro J, U R, Yang M, Go K, et al. Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers. Aging Cell. 2018;17:e12761 pubmed publisher
Shadrach J, Pierchala B. Semaphorin3A Signaling Is Dispensable for Motor Axon Reinnervation of the Adult Neuromuscular Junction. Eneuro. 2018;5: pubmed publisher
Ma K, Qin L, Matas E, Duffney L, Liu A, Yan Z. Histone deacetylase inhibitor MS-275 restores social and synaptic function in a Shank3-deficient mouse model of autism. Neuropsychopharmacology. 2018;43:1779-1788 pubmed publisher
Rubio Solsona E, Marti S, Vilchez J, Palau F, Hoenicka J. ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism. PLoS ONE. 2018;13:e0197254 pubmed publisher
Horard B, Sapey Triomphe L, Bonnefoy E, Loppin B. ASF1 is required to load histones on the HIRA complex in preparation of paternal chromatin assembly at fertilization. Epigenetics Chromatin. 2018;11:19 pubmed publisher
Ciossani G, Overlack K, Petrovic A, Huis In t Veld P, Koerner C, Wohlgemuth S, et al. The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases. J Biol Chem. 2018;293:10084-10101 pubmed publisher
Chen Y, Ramachandran A, Zhang Y, Koshy R, George A. The ER Ca2+ sensor STIM1 can activate osteoblast and odontoblast differentiation in mineralized tissues. Connect Tissue Res. 2018;59:6-12 pubmed publisher
Yuan W, Zhou Y, Fan Y, Tao Y, Zhong W. Orsay δ Protein Is Required for Nonlytic Viral Egress. J Virol. 2018;92: pubmed publisher
Lettieri Barbato D, Cannata S, Casagrande V, Ciriolo M, Aquilano K. Time-controlled fasting prevents aging-like mitochondrial changes induced by persistent dietary fat overload in skeletal muscle. PLoS ONE. 2018;13:e0195912 pubmed publisher
Yamaguchi H, Oda T, Kikkawa M, Takeda H. Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly. elife. 2018;7: pubmed publisher
Merlo S, Spampinato S, Beneventano M, Sortino M. The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death. Sci Rep. 2018;8:7297 pubmed publisher
Smith R, Sellou H, Chapuis C, Huet S, Timinszky G. CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly(ADP-ribose)-dependent chromatin relaxation. Nucleic Acids Res. 2018;46:6087-6098 pubmed publisher
Penke L, Speth J, Dommeti V, White E, Bergin I, Peters Golden M. FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis. J Clin Invest. 2018;128:2389-2405 pubmed publisher
Gurden M, Anderhub S, Faisal A, Linardopoulos S. Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis. Oncotarget. 2018;9:19525-19542 pubmed publisher
Gou Y, Li J, Wu J, Gupta R, Cho I, Ho T, et al. Prmt1 regulates craniofacial bone formation upstream of Msx1. Mech Dev. 2018;152:13-20 pubmed publisher
Otero M, Fernandez Bessone I, Hallberg A, Cromberg L, De Rossi M, Saez T, et al. Proteasome stress leads to APP axonal transport defects by promoting its amyloidogenic processing in lysosomes. J Cell Sci. 2018;131: pubmed publisher
Tilley F, Gallon M, Luo C, Danson C, Zhou J, Cullen P. Retromer associates with the cytoplasmic amino-terminus of polycystin-2. J Cell Sci. 2018;131: pubmed publisher
Shiloh R, Gilad Y, Ber Y, Eisenstein M, Aweida D, Bialik S, et al. Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy. Nat Commun. 2018;9:1759 pubmed publisher
Picchio L, Legagneux V, Deschamps S, Renaud Y, Chauveau S, Paillard L, et al. Bruno-3 regulates sarcomere component expression and contributes to muscle phenotypes of myotonic dystrophy type 1. Dis Model Mech. 2018;11: pubmed publisher
Matsumoto N, Sekiya M, Tohyama K, Ishiyama Matsuura E, Sun Wada G, Wada Y, et al. Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment. Sci Rep. 2018;8:6701 pubmed publisher
Sequerra E, Goyal R, Castro P, Levin J, Borodinsky L. NMDA Receptor Signaling Is Important for Neural Tube Formation and for Preventing Antiepileptic Drug-Induced Neural Tube Defects. J Neurosci. 2018;38:4762-4773 pubmed publisher
Reina J, Gottardo M, Riparbelli M, Llamazares S, Callaini G, Gonzalez C. Centrobin is essential for C-tubule assembly and flagellum development in Drosophila melanogaster spermatogenesis. J Cell Biol. 2018;217:2365-2372 pubmed publisher
Urbano R, Karlinsey J, Libby S, Doulias P, Ischiropoulos H, Warheit Niemi H, et al. Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence. Cell Host Microbe. 2018;23:594-606.e7 pubmed publisher
Balmus G, Larrieu D, Barros A, Collins C, Abrudan M, Demir M, et al. Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome. Nat Commun. 2018;9:1700 pubmed publisher
Campbell J, Heikkila J. Effect of hemin, baicalein and heme oxygenase-1 (HO-1) enzyme activity inhibitors on Cd-induced accumulation of HO-1, HSPs and aggresome-like structures in Xenopus kidney epithelial cells. Comp Biochem Physiol C Toxicol Pharmacol. 2018;210:1-17 pubmed publisher
De Pace R, Skirzewski M, Damme M, Mattera R, Mercurio J, Foster A, et al. Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome. PLoS Genet. 2018;14:e1007363 pubmed publisher
Gerhards N, Blomen V, Mutlu M, Nieuwenhuis J, Howald D, Guyader C, et al. Haploid genetic screens identify genetic vulnerabilities to microtubule-targeting agents. Mol Oncol. 2018;12:953-971 pubmed publisher
Dong K, Guo X, Chen W, Hsu A, Shao Q, Chen J, et al. Mesenchyme homeobox 1 mediates transforming growth factor-β (TGF-β)-induced smooth muscle cell differentiation from mouse mesenchymal progenitors. J Biol Chem. 2018;293:8712-8719 pubmed publisher
Shosha E, Xu Z, Narayanan S, Lemtalsi T, Fouda A, Rojas M, et al. Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1. Int J Mol Sci. 2018;19: pubmed publisher
Wu Z, Zhao J, Qiu M, Mi Z, Meng M, Guo Y, et al. CRISPR/Cas9 Mediated GFP Knock-in at the MAP1LC3B Locus in 293FT Cells Is Better for Bona Fide Monitoring Cellular Autophagy. Biotechnol J. 2018;13:e1700674 pubmed publisher
Hareza A, Bakun M, Åšwiderska B, Dudkiewicz M, Koscielny A, Bajur A, et al. Phosphoproteomic insights into processes influenced by the kinase-like protein DIA1/C3orf58. Peerj. 2018;6:e4599 pubmed publisher
Schorch B, Heni H, Zahaf N, Brummer T, Mione M, Schmidt G, et al. Targeting oncogenic Ras by the Clostridium perfringens toxin TpeL. Oncotarget. 2018;9:16489-16500 pubmed publisher
Gallastegui E, Domuro C, Serratosa J, Larrieux A, Sin L, Martinez J, et al. p27Kip1 regulates alpha-synuclein expression. Oncotarget. 2018;9:16368-16379 pubmed publisher
Finley L, Vardhana S, Carey B, Alonso Curbelo D, Koche R, Chen Y, et al. Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity. Nat Cell Biol. 2018;20:565-574 pubmed publisher
Monroy B, Sawyer D, Ackermann B, Borden M, Tan T, Ori McKenney K. Competition between microtubule-associated proteins directs motor transport. Nat Commun. 2018;9:1487 pubmed publisher
Yoneyama Y, Lanzerstorfer P, Niwa H, Umehara T, Shibano T, Yokoyama S, et al. IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling. elife. 2018;7: pubmed publisher
Jian Y, Wang M, Zhang Y, Ou R, Zhu Z, Ou Y, et al. Jade family PHD finger 3 (JADE3) increases cancer stem cell-like properties and tumorigenicity in colon cancer. Cancer Lett. 2018;428:1-11 pubmed publisher
Dix C, Matthews H, Uroz M, McLaren S, Wolf L, Heatley N, et al. The Role of Mitotic Cell-Substrate Adhesion Re-modeling in Animal Cell Division. Dev Cell. 2018;45:132-145.e3 pubmed publisher
Puri C, Vicinanza M, Ashkenazi A, Gratian M, Zhang Q, Bento C, et al. The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A. Dev Cell. 2018;45:114-131.e8 pubmed publisher
Kivinen N. The role of autophagy in age-related macular degeneration. Acta Ophthalmol. 2018;96 Suppl A110:1-50 pubmed publisher
Bonin S, Parascandolo A, Aversa C, Barbazza R, Tsuchida N, Castellone M, et al. Reduced expression of α-L-Fucosidase-1 (FUCA-1) predicts recurrence and shorter cancer specific survival in luminal B LN+ breast cancer patients. Oncotarget. 2018;9:15228-15238 pubmed publisher
Shrestha N, Shrestha H, Ryu T, Kim H, Simkhada S, Cho Y, et al. δ-Catenin Increases the Stability of EGFR by Decreasing c-Cbl Interaction and Enhances EGFR/Erk1/2 Signaling in Prostate Cancer. Mol Cells. 2018;41:320-330 pubmed publisher
Copic A, Antoine Bally S, Giménez Andrés M, La Torre Garay C, Antonny B, Manni M, et al. A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets. Nat Commun. 2018;9:1332 pubmed publisher
You Z, Zhang S, Shen S, Yang J, Ding W, Yang L, et al. Cognitive impairment in a rat model of neuropathic pain: role of hippocampal microtubule stability. Pain. 2018;159:1518-1528 pubmed publisher
Zheng G, Kanchwala M, Xing C, Yu H. MCM2-7-dependent cohesin loading during S phase promotes sister-chromatid cohesion. elife. 2018;7: pubmed publisher
Dobrian A, Huyck R, Glenn L, Gottipati V, Haynes B, Hansson G, et al. Activation of the 12/15 lipoxygenase pathway accompanies metabolic decline in db/db pre-diabetic mice. Prostaglandins Other Lipid Mediat. 2018;136:23-32 pubmed publisher
Bazzani L, Donnini S, Giachetti A, Christofori G, Ziche M. PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells. Oncotarget. 2018;9:14939-14958 pubmed publisher
Banks C, Thornton J, Eubanks C, Adams M, Miah S, Boanca G, et al. A Structured Workflow for Mapping Human Sin3 Histone Deacetylase Complex Interactions Using Halo-MudPIT Affinity-Purification Mass Spectrometry. Mol Cell Proteomics. 2018;17:1432-1447 pubmed publisher
Santos Llamas A, Monte M, Marin J, Perez M. Dysregulation of autophagy in rat liver with mitochondrial DNA depletion induced by the nucleoside analogue zidovudine. Arch Toxicol. 2018;92:2109-2118 pubmed publisher
Sanjurjo L, Aran G, Téllez É, Amézaga N, Armengol C, Lopez D, et al. CD5L Promotes M2 Macrophage Polarization through Autophagy-Mediated Upregulation of ID3. Front Immunol. 2018;9:480 pubmed publisher
Takahashi A, Loo T, Okada R, Kamachi F, Watanabe Y, Wakita M, et al. Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells. Nat Commun. 2018;9:1249 pubmed publisher
Errico Provenzano A, Amatori S, Nasoni M, Persico G, Russo S, Mastrogiacomo A, et al. Effects of Fifty-Hertz Electromagnetic Fields on Granulocytic Differentiation of ATRA-Treated Acute Promyelocytic Leukemia NB4 Cells. Cell Physiol Biochem. 2018;46:389-400 pubmed publisher
Mitxelena J, Apraiz A, Vallejo Rodríguez J, García Santisteban I, Fullaondo A, Alvarez Fernandez M, et al. An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability. Nucleic Acids Res. 2018;46:4546-4559 pubmed publisher
Heller G, Altenberger C, Steiner I, Topakian T, Ziegler B, Tomasich E, et al. DNA methylation of microRNA-coding genes in non-small-cell lung cancer patients. J Pathol. 2018;245:387-398 pubmed publisher
Nakamura A, Nakata D, Kakoi Y, Kunitomo M, Murai S, Ebara S, et al. CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells. Oncotarget. 2018;9:13474-13487 pubmed publisher
Ganier O, Schnerch D, Oertle P, Lim R, Plodinec M, Nigg E. Structural centrosome aberrations promote non-cell-autonomous invasiveness. EMBO J. 2018;37: pubmed publisher
Chen A, Tiosano D, Guran T, Baris H, Bayram Y, Mory A, et al. Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum Mol Genet. 2018;27:1913-1926 pubmed publisher
Edenharter O, Schneuwly S, Navarro J. Mitofusin-Dependent ER Stress Triggers Glial Dysfunction and Nervous System Degeneration in a Drosophila Model of Friedreich's Ataxia. Front Mol Neurosci. 2018;11:38 pubmed publisher
Elisha Y, Kalchenko V, Kuznetsov Y, Geiger B. Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells. Sci Rep. 2018;8:4986 pubmed publisher
Yang Z, Follett J, Kerr M, Clairfeuille T, Chandra M, Collins B, et al. Sorting nexin 27 (SNX27) regulates the trafficking and activity of the glutamine transporter ASCT2. J Biol Chem. 2018;293:6802-6811 pubmed publisher
Maticzka D, Ilik I, Aktas T, Backofen R, Akhtar A. uvCLAP is a fast and non-radioactive method to identify in vivo targets of RNA-binding proteins. Nat Commun. 2018;9:1142 pubmed publisher
Ji J, Yu Y, Li Z, Chen M, Deng R, Huang X, et al. XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells. Theranostics. 2018;8:1494-1510 pubmed publisher
Bergiers I, Andrews T, Vargel Bölükbaşı Ö, Buness A, Janosz E, Lopez Anguita N, et al. Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis. elife. 2018;7: pubmed publisher
Koch P, Miller H, Yu G, Tallarico J, Sorger P, Wang Y, et al. A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling. ACS Chem Biol. 2018;13:1066-1081 pubmed publisher
Campbell A, Shadle S, Jagannathan S, Lim J, Resnick R, Tawil R, et al. NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins. elife. 2018;7: pubmed publisher
Lin C, Kitagawa M, Tang X, Hou M, Wu J, Qu D, et al. CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. Nat Commun. 2018;9:1039 pubmed publisher
Rivat C, Sar C, Mechaly I, Leyris J, Diouloufet L, Sonrier C, et al. Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice. Nat Commun. 2018;9:1042 pubmed publisher
Zhang B, Tran U, Wessely O. Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney. Development. 2018;145: pubmed publisher
Johnson B, Vanblargan L, Xu W, White J, Shan C, Shi P, et al. Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability. Immunity. 2018;48:487-499.e5 pubmed publisher
Limpose K, Trego K, Li Z, Leung S, Sarker A, Shah J, et al. Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer. Nucleic Acids Res. 2018;46:4515-4532 pubmed publisher
Dauksaite V, Gotthardt M. Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4. Nucleic Acids Res. 2018;46:5227-5238 pubmed publisher
Chano T, Kita H, Avnet S, Lemma S, Baldini N. Prominent role of RAB39A-RXRB axis in cancer development and stemness. Oncotarget. 2018;9:9852-9866 pubmed publisher
Guijo M, Ceballos Chávez M, Gómez Marín E, Basurto Cayuela L, Reyes J. Expression of TDRD9 in a subset of lung carcinomas by CpG island hypomethylation protects from DNA damage. Oncotarget. 2018;9:9618-9631 pubmed publisher
Danyukova T, Ariunbat K, Thelen M, Brocke Ahmadinejad N, Mole S, Storch S. Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation. Hum Mol Genet. 2018;27:1711-1722 pubmed publisher
Takahashi K, Ehata S, Koinuma D, Morishita Y, Soda M, Mano H, et al. Pancreatic tumor microenvironment confers highly malignant properties on pancreatic cancer cells. Oncogene. 2018;37:2757-2772 pubmed publisher
Burgess S, Mukherjee M, Sabir S, Joseph N, Gutiérrez Caballero C, Richards M, et al. Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix. EMBO J. 2018;37: pubmed publisher
García Heredia J, Carnero A. NUMB and NUMBL differences in gene regulation. Oncotarget. 2018;9:9219-9234 pubmed publisher
Audano M, Pedretti S, Cermenati G, Brioschi E, Diaferia G, Ghisletti S, et al. Zc3h10 is a novel mitochondrial regulator. EMBO Rep. 2018;19: pubmed publisher
Maltese M, Stanic J, Tassone A, Sciamanna G, Ponterio G, Vanni V, et al. Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatum. elife. 2018;7: pubmed publisher
Reimer L, Vesterager L, Betzer C, Zheng J, Nielsen L, Kofoed R, et al. Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death. Neurobiol Dis. 2018;115:17-28 pubmed publisher
Horton J, Stefanick D, Cağlayan M, Zhao M, Janoshazi A, Prasad R, et al. XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity. DNA Repair (Amst). 2018;64:26-33 pubmed publisher
Besharat Z, Abballe L, Cicconardi F, Bhutkar A, Grassi L, Le Pera L, et al. Foxm1 controls a pro-stemness microRNA network in neural stem cells. Sci Rep. 2018;8:3523 pubmed publisher
Vonk L, van Dooremalen S, Liv N, Klumperman J, Coffer P, Saris D, et al. Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro. Theranostics. 2018;8:906-920 pubmed publisher
Ott C, Nachmias D, Adar S, Jarnik M, Sherman S, Birnbaum R, et al. VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis. Sci Rep. 2018;8:3353 pubmed publisher
Kooreman N, Kim Y, de Almeida P, Termglinchan V, Diecke S, Shao N, et al. Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo. Cell Stem Cell. 2018;22:501-513.e7 pubmed publisher
Annibaldi A, Wicky John S, Vanden Berghe T, Swatek K, Ruan J, Liccardi G, et al. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2. Mol Cell. 2018;69:566-580.e5 pubmed publisher
Lin K, Ma W, Scharner J, Liu Y, Krainer A. A human-specific switch of alternatively spliced AFMID isoforms contributes to TP53 mutations and tumor recurrence in hepatocellular carcinoma. Genome Res. 2018;: pubmed publisher
Maruzuru Y, Ichinohe T, Sato R, Miyake K, Okano T, Suzuki T, et al. Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication. Cell Host Microbe. 2018;23:254-265.e7 pubmed publisher
Arquint C, Cubizolles F, Morand A, Schmidt A, Nigg E. The SKP1-Cullin-F-box E3 ligase βTrCP and CDK2 cooperate to control STIL abundance and centriole number. Open Biol. 2018;8: pubmed publisher
Meng H, Liu Z, Li X, Wang H, Jin T, Wu G, et al. Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis. Proc Natl Acad Sci U S A. 2018;115:E2001-E2009 pubmed publisher
Jurmeister S, Ramos Montoya A, Sandi C, Pértega Gomes N, Wadhwa K, Lamb A, et al. Identification of potential therapeutic targets in prostate cancer through a cross-species approach. EMBO Mol Med. 2018;10: pubmed publisher
Parascandolo A, Laukkanen M, De Rosa N, Ugolini C, Cantisani M, Cirafici A, et al. A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma. Oncotarget. 2018;9:4496-4510 pubmed publisher
Borek A, Sokolowska Wedzina A, Chodaczek G, Otlewski J. Generation of high-affinity, internalizing anti-FGFR2 single-chain variable antibody fragment fused with Fc for targeting gastrointestinal cancers. PLoS ONE. 2018;13:e0192194 pubmed publisher
Urra S, Fischer M, Martinez J, Veliz L, Orellana P, Solar A, et al. Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis?. Oncotarget. 2018;9:2445-2467 pubmed publisher
Oshima M, Knoch K, Diedisheim M, Petzold A, Cattan P, Bugliani M, et al. Virus-like infection induces human β cell dedifferentiation. JCI Insight. 2018;3: pubmed publisher
Yan M, Turgeon P, Man H, Dubinsky M, Ho J, El Rass S, et al. Histone acetyltransferase 7 (KAT7)-dependent intragenic histone acetylation regulates endothelial cell gene regulation. J Biol Chem. 2018;293:4381-4402 pubmed publisher
Borroni A, Emanuelli A, Shah P, Ilic N, Apel Sarid L, Paolini B, et al. Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin. Aging Cell. 2018;17: pubmed publisher
Quintanal Villalonga Á, Ojeda Márquez L, Marrugal A, Yagüe P, Ponce Aix S, Salinas A, et al. The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction. Sci Rep. 2018;8:2394 pubmed publisher
Fazakerley D, Chaudhuri R, Yang P, Maghzal G, Thomas K, Krycer J, et al. Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance. elife. 2018;7: pubmed publisher
Sassa T, Tadaki M, Kiyonari H, Kihara A. Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice. FASEB J. 2018;32:2966-2978 pubmed publisher
Kruppa A, Kishi Itakura C, Masters T, Rorbach J, Grice G, Kendrick Jones J, et al. Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell. 2018;44:484-499.e6 pubmed publisher
Haneda M, Hayashi S, Matsumoto T, Hashimoto S, Takayama K, Chinzei N, et al. Depletion of aquaporin 1 decreased ADAMTS‑4 expression in human chondrocytes. Mol Med Rep. 2018;17:4874-4882 pubmed publisher
Amaral M, Nery L, Leite C, de Azevedo Junior W, Campos M. Pre-clinical effects of metformin and aspirin on the cell lines of different breast cancer subtypes. Invest New Drugs. 2018;36:782-796 pubmed publisher
Unbekandt M, Belshaw S, Bower J, Clarke M, Cordes J, Crighton D, et al. Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer. Cancer Res. 2018;78:2096-2114 pubmed publisher
Codron P, Cassereau J, Vourc H P, Veyrat Durebex C, Blasco H, Kane S, et al. Primary fibroblasts derived from sporadic amyotrophic lateral sclerosis patients do not show ALS cytological lesions. Amyotroph Lateral Scler Frontotemporal Degener. 2018;19:446-456 pubmed publisher
McHedlishvili N, Matthews H, Corrigan A, Baum B. Two-step interphase microtubule disassembly aids spindle morphogenesis. BMC Biol. 2018;16:14 pubmed publisher
Nag R, Niggli S, Sousa Guimarães S, Vazquez Pianzola P, Suter B. Mms19 is a mitotic gene that permits Cdk7 to be fully active as a Cdk-activating kinase. Development. 2018;145: pubmed publisher
Ryan V, Dignon G, Zerze G, Chabata C, Silva R, Conicella A, et al. Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation. Mol Cell. 2018;69:465-479.e7 pubmed publisher
Madero Pérez J, Fdez E, Fernández B, Lara Ordóñez A, Blanca Ramírez M, Gomez Suaga P, et al. Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation. Mol Neurodegener. 2018;13:3 pubmed publisher
Drabikowski K, Ferralli J, Kistowski M, Oledzki J, Dadlez M, Chiquet Ehrismann R. Comprehensive list of SUMO targets in Caenorhabditis elegans and its implication for evolutionary conservation of SUMO signaling. Sci Rep. 2018;8:1139 pubmed publisher
Goreczny G, Forsythe I, Turner C. Hic-5 regulates fibrillar adhesion formation to control tumor extracellular matrix remodeling through interaction with tensin1. Oncogene. 2018;37:1699-1713 pubmed publisher
Fung E, Richter C, Yang H, Schäffer I, Fischer R, Kessler B, et al. FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration. EMBO Rep. 2018;19: pubmed publisher
Sukegawa S, Miyagi E, Bouamr F, Farkašová H, Strebel K. Mannose Receptor 1 Restricts HIV Particle Release from Infected Macrophages. Cell Rep. 2018;22:786-795 pubmed publisher
Lalisse S, Hua J, Lenoir M, Linck N, Rassendren F, Ulmann L. Sensory neuronal P2RX4 receptors controls BDNF signaling in inflammatory pain. Sci Rep. 2018;8:964 pubmed publisher
Zhou D, Fu H, Xiao L, Mo H, Zhuo H, Tian X, et al. Fibroblast-Specific β-Catenin Signaling Dictates the Outcome of AKI. J Am Soc Nephrol. 2018;29:1257-1271 pubmed publisher
Wang Y, Sun Z, Szyf M. S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells. Oncotarget. 2017;8:111866-111881 pubmed publisher
Kaneda M, Sakagami H, Hida Y, Ohtsuka T, Satou N, Ishibashi Y, et al. Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology. Sci Rep. 2018;8:727 pubmed publisher
Keller S, Zwingenberger G, Ebert K, Hasenauer J, Wasmuth J, Maier D, et al. Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines. Mol Oncol. 2018;12:441-462 pubmed publisher
Yamada E, Nakaoka S, Klein L, Reith E, Langer S, Hopfensperger K, et al. Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo. Cell Host Microbe. 2018;23:110-120.e7 pubmed publisher
Fernández Barrera J, Bernabé Rubio M, Casares Arias J, Rangel L, Fernández Martín L, Correas I, et al. The actin-MRTF-SRF transcriptional circuit controls tubulin acetylation via α-TAT1 gene expression. J Cell Biol. 2018;217:929-944 pubmed publisher
Espinosa Raya J, Cruz Raya U, López Martínez M, Picazo O. Choline acetyltransferase and TrkA expression, as well as the improvement in cognition produced by E2 and P4 in ovariectomized rats, are blocked by ICI 182 780 and RU486. Behav Pharmacol. 2018;29:457-461 pubmed publisher
Tripon R, Olah J, Nasir T, Csincsik L, Li C, Szunyogh S, et al. Localization of the zinc binding tubulin polymerization promoting protein in the mice and human eye. J Trace Elem Med Biol. 2018;49:222-230 pubmed publisher
Sulaiman A, McGarry S, Li L, Jia D, Ooi S, Addison C, et al. Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple-negative breast cancer in both mesenchymal and epithelial states. Mol Oncol. 2018;12:423-440 pubmed publisher
Bandla H, Dasgupta D, Mauer A, Nozickova B, Kumar S, Hirsova P, et al. Deletion of endoplasmic reticulum stress-responsive co-chaperone p58IPK protects mice from diet-induced steatohepatitis. Hepatol Res. 2018;48:479-494 pubmed publisher
Mangal S, Sacher J, Kim T, Osório D, Motegi F, Carvalho A, et al. TPXL-1 activates Aurora A to clear contractile ring components from the polar cortex during cytokinesis. J Cell Biol. 2018;217:837-848 pubmed publisher
Gayrard C, Bernaudin C, Dejardin T, Seiler C, Borghi N. Src- and confinement-dependent FAK activation causes E-cadherin relaxation and β-catenin activity. J Cell Biol. 2018;217:1063-1077 pubmed publisher
Kim K, Maio N, Singh A, Rouault T. Cytosolic HSC20 integrates de novo iron-sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients. Hum Mol Genet. 2018;27:837-852 pubmed publisher
Döhner K, Ramos Nascimento A, Bialy D, Anderson F, Hickford Martinez A, Rother F, et al. Importin ?1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons. PLoS Pathog. 2018;14:e1006823 pubmed publisher
Khalil S, Holy M, Grado S, Fleming R, Kurita R, Nakamura Y, et al. A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2. Blood Adv. 2017;1:1181-1194 pubmed publisher
Imtiaz A, Belyantseva I, Beirl A, Fenollar Ferrer C, Bashir R, Bukhari I, et al. CDC14A phosphatase is essential for hearing and male fertility in mouse and human. Hum Mol Genet. 2018;27:780-798 pubmed publisher
Gong Y, Wang X, Shang X, Xiao S, Li W, Shang Y, et al. Tetratricopeptide repeat domain 3 overexpression tends to form aggregates and inhibit ubiquitination and degradation of DNA polymerase γ. Oncotarget. 2017;8:106475-106485 pubmed publisher
Kottemann M, Conti B, Lach F, Smogorzewska A. Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity. Mol Cell. 2018;69:24-35.e5 pubmed publisher
Kruse T, Biedenkopf N, Hertz E, Dietzel E, Stalmann G, López Méndez B, et al. The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30. Mol Cell. 2018;69:136-145.e6 pubmed publisher
Hadjadj D, Kim S, Denecker T, Ben Driss L, Cadoret J, Maric C, et al. A hypothesis-driven approach identifies CDK4 and CDK6 inhibitors as candidate drugs for treatments of adrenocortical carcinomas. Aging (Albany NY). 2017;9:2695-2716 pubmed publisher
Khalil S, Delehanty L, Grado S, Holy M, White Z, Freeman K, et al. Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor. J Exp Med. 2018;215:661-679 pubmed publisher
Chen R, Xu M, Nagati J, Garcia J. Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells. PLoS ONE. 2017;12:e0190241 pubmed publisher
Lien W, Chen T, Sheu S, Lin T, Kang F, Yu C, et al. 7-hydroxy-staurosporine, UCN-01, induces DNA damage response, and autophagy in human osteosarcoma U2-OS cells. J Cell Biochem. 2018;119:4729-4741 pubmed publisher
Han B, Antkowiak K, Fan X, Rutigliano M, Ryder S, Griffin E. Polo-like Kinase Couples Cytoplasmic Protein Gradients in the C. elegans Zygote. Curr Biol. 2018;28:60-69.e8 pubmed publisher
Malaby A, Das S, Chakravarthy S, Irving T, Bilsel O, Lambright D. Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors. Structure. 2018;26:106-117.e6 pubmed publisher
Pleiner T, Bates M, Gorlich D. A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. J Cell Biol. 2018;217:1143-1154 pubmed publisher
Chan Y, Fugger K, West S. Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations. Nat Cell Biol. 2018;20:92-103 pubmed publisher
Fang J, Coon B, Gillis N, Chen Z, Qiu J, Chittenden T, et al. Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nat Commun. 2017;8:2149 pubmed publisher
Lucena Cacace A, Otero Albiol D, Jimenez Garcia M, Peinado Serrano J, Carnero A. NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis. Oncotarget. 2017;8:99514-99530 pubmed publisher
Wang Y, Hariharan A, Bastianello G, Toyama Y, Shivashankar G, Foiani M, et al. DNA damage causes rapid accumulation of phosphoinositides for ATR signaling. Nat Commun. 2017;8:2118 pubmed publisher
Keller S, Kneissl J, Grabher Meier V, Heindl S, Hasenauer J, Maier D, et al. Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis. BMC Cancer. 2017;17:845 pubmed publisher
Samuelsson M, Potrzebowska K, Lehtonen J, Beech J, Skorova E, Uronen Hansson H, et al. RhoB controls the Rab11-mediated recycling and surface reappearance of LFA-1 in migrating T lymphocytes. Sci Signal. 2017;10: pubmed publisher
Low S, Barnes J, Zammit P, Beauchamp J. Delta-like 4 Activates Notch3 to Regulate Self-Renewal in Skeletal Muscle Stem Cells. Stem Cells. 2017;: pubmed publisher
Zhou Z, Liu A, Xia S, Leung C, Qi J, Meng Y, et al. The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning. Nat Neurosci. 2018;21:50-62 pubmed publisher
García Heredia J, Carnero A. The cargo protein MAP17 (PDZK1IP1) regulates the immune microenvironment. Oncotarget. 2017;8:98580-98597 pubmed publisher
Ferreras S, Fernandez G, Danelon V, Pisano M, Masseroni L, Chapleau C, et al. Cdk5 Is Essential for Amphetamine to Increase Dendritic Spine Density in Hippocampal Pyramidal Neurons. Front Cell Neurosci. 2017;11:372 pubmed publisher
Lee Y, Hiwatashi Y, Hotta T, Xie T, Doonan J, Liu B. The Mitotic Function of Augmin Is Dependent on Its Microtubule-Associated Protein Subunit EDE1 in Arabidopsis thaliana. Curr Biol. 2017;27:3891-3897.e4 pubmed publisher
Pinto M, Nissanka N, Moraes C. Lack of Parkin Anticipates the Phenotype and Affects Mitochondrial Morphology and mtDNA Levels in a Mouse Model of Parkinson's Disease. J Neurosci. 2018;38:1042-1053 pubmed publisher
Yurko N, Liu X, Yamazaki T, Hoque M, Tian B, Manley J. MPK1/SLT2 Links Multiple Stress Responses with Gene Expression in Budding Yeast by Phosphorylating Tyr1 of the RNAP II CTD. Mol Cell. 2017;68:913-925.e3 pubmed publisher
Simečková S, Fedr R, Remšík J, Kahounova Z, Slabáková E, Soucek K. Multiparameter cytometric analysis of complex cellular response. Cytometry A. 2017;: pubmed publisher
Gonzales F, Howell K, Dozier L, Anagnostaras S, Patrick G. Proteasome phosphorylation regulates cocaine-induced sensitization. Mol Cell Neurosci. 2018;88:62-69 pubmed publisher
Umaña A, Iwahori S, Kalejta R. Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk). ACS Chem Biol. 2018;13:189-199 pubmed publisher
Ban N, Ozawa Y, Osada H, Lin J, Toda E, Watanabe M, et al. Neuroprotective role of retinal SIRT3 against acute photo-stress. NPJ Aging Mech Dis. 2017;3:19 pubmed publisher
Szabó A, Olah J, Szunyogh S, Lehotzky A, Szénási T, Csaplár M, et al. Modulation Of Microtubule Acetylation By The Interplay Of TPPP/p25, SIRT2 And New Anticancer Agents With Anti-SIRT2 Potency. Sci Rep. 2017;7:17070 pubmed publisher
Sato K, Misawa N, Takeuchi J, Kobayashi T, Izumi T, Aso H, et al. Experimental Adaptive Evolution of Simian Immunodeficiency Virus SIVcpz to Pandemic Human Immunodeficiency Virus Type 1 by Using a Humanized Mouse Model. J Virol. 2018;92: pubmed publisher
Lucena Cacace A, Otero Albiol D, Jimenez Garcia M, Muñoz Galvan S, Carnero A. NAMPT Is a Potent Oncogene in Colon Cancer Progression that Modulates Cancer Stem Cell Properties and Resistance to Therapy through Sirt1 and PARP. Clin Cancer Res. 2018;24:1202-1215 pubmed publisher
Smith K, Granberry M, Tan M, Daniel C, Gassman N. Dihydroxyacetone induces G2/M arrest and apoptotic cell death in A375P melanoma cells. Environ Toxicol. 2017;: pubmed publisher
Martin L, Ribas R, Simigdala N, Schuster E, Pancholi S, Tenev T, et al. Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance. Nat Commun. 2017;8:1865 pubmed publisher
Peela N, Barrientos E, Truong D, Mouneimne G, Nikkhah M. Effect of suberoylanilide hydroxamic acid (SAHA) on breast cancer cells within a tumor-stroma microfluidic model. Integr Biol (Camb). 2017;9:988-999 pubmed publisher
Ito S, Okuda S, Abe M, Fujimoto M, Onuki T, Nishimura T, et al. Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells. Nat Commun. 2017;8:1834 pubmed publisher
Spohrer S, Groß R, Nalbach L, Schwind L, Stumpf H, Menger M, et al. Functional interplay between the transcription factors USF1 and PDX-1 and protein kinase CK2 in pancreatic β-cells. Sci Rep. 2017;7:16367 pubmed publisher
Nair R, Aboobacker S, Mutalik S, Kalthur G, Adiga S. Sperm-derived factors enhance the in vitro developmental potential of haploid parthenotes. Zygote. 2017;:1-14 pubmed publisher
Messaoudi K, Ali A, Ishaq R, Palazzo A, Sliwa D, Bluteau O, et al. Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect. Nat Commun. 2017;8:1786 pubmed publisher
Devambez I, Van Dijk J, Benlefki S, Layalle S, Grau Y, Rogowski K, et al. Identification of DmTTLL5 as a Major Tubulin Glutamylase in the Drosophila Nervous System. Sci Rep. 2017;7:16254 pubmed publisher
Khatri N, Gilbert J, Huo Y, Sharaflari R, Nee M, Qiao H, et al. The Autism Protein Ube3A/E6AP Remodels Neuronal Dendritic Arborization via Caspase-Dependent Microtubule Destabilization. J Neurosci. 2018;38:363-378 pubmed publisher
Baron O, Boudi A, Dias C, Schilling M, Nölle A, Vizcay Barrena G, et al. Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration. Curr Biol. 2017;27:3626-3642.e6 pubmed publisher
Li Q, Li Y, Wang X, Qi J, Jin X, Tong H, et al. Fbxl4 Serves as a Clock Output Molecule that Regulates Sleep through Promotion of Rhythmic Degradation of the GABAA Receptor. Curr Biol. 2017;27:3616-3625.e5 pubmed publisher
Stepanichev M, Onufriev M, Aniol V, Freiman S, Brandstaetter H, Winter S, et al. Effects of cerebrolysin on nerve growth factor system in the aging rat brain. Restor Neurol Neurosci. 2017;35:571-581 pubmed publisher
Kessler S, Lederer E, Laggai S, Golob Schwarzl N, Hosseini K, Petzold J, et al. IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer. Oncotarget. 2017;8:89736-89745 pubmed publisher
He G, Yang X, Wang G, Qi J, Mao R, Wu Z, et al. Cdk7 Is Required for Activity-Dependent Neuronal Gene Expression, Long-Lasting Synaptic Plasticity and Long-Term Memory. Front Mol Neurosci. 2017;10:365 pubmed publisher
Lyons J, Joca H, Law R, Williams K, Kerr J, Shi G, et al. Microtubules tune mechanotransduction through NOX2 and TRPV4 to decrease sclerostin abundance in osteocytes. Sci Signal. 2017;10: pubmed publisher
Hu J, Sun F, Handel M. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018;98:102-114 pubmed publisher
Tankiewicz Kwedlo A, Hermanowicz J, Domaniewski T, Pawlak K, Rusak M, Pryczynicz A, et al. Simultaneous use of erythropoietin and LFM-A13 as a new therapeutic approach for colorectal cancer. Br J Pharmacol. 2017;: pubmed publisher
Maschalidi S, Nunes Hasler P, Nascimento C, Sallent I, Lannoy V, Garfa Traoré M, et al. UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells. Nat Commun. 2017;8:1640 pubmed publisher
Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle N, et al. Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. Cancer Cell. 2017;32:824-839.e8 pubmed publisher
Bradshaw N, Ukkola Vuoti L, Pankakoski M, Zheutlin A, Ortega Alonso A, Torniainen Holm M, et al. The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484. Open Biol. 2017;7: pubmed publisher
Gao H, Liu H, Tang T, Huang X, Wang D, Li Y, et al. Oleanonic acid ameliorates pressure overload-induced cardiac hypertrophy in rats: The role of PKCζ-NF-κB pathway. Mol Cell Endocrinol. 2018;470:259-268 pubmed publisher
Bondeson D, Smith B, Burslem G, Buhimschi A, Hines J, Jaime Figueroa S, et al. Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead. Cell Chem Biol. 2018;25:78-87.e5 pubmed publisher
Burslem G, Smith B, Lai A, Jaime Figueroa S, McQuaid D, Bondeson D, et al. The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study. Cell Chem Biol. 2018;25:67-77.e3 pubmed publisher
Sato Y, Ohtsubo H, Nihei N, Kaneko T, Sato Y, Adachi S, et al. Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle. FASEB J. 2018;32:1428-1439 pubmed publisher
Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska Skorska M, Gupta A, et al. Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia. Clin Cancer Res. 2018;24:608-618 pubmed publisher
Roubinet C, Tsankova A, Pham T, Monnard A, Caussinus E, Affolter M, et al. Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells. Nat Commun. 2017;8:1383 pubmed publisher
Jenkins B, Saunders H, Record H, Johnson Schlitz D, Wildonger J. Effects of mutating ?-tubulin lysine 40 on sensory dendrite development. J Cell Sci. 2017;130:4120-4131 pubmed publisher
Bosshard M, Aprigliano R, Gattiker C, Palibrk V, Markkanen E, Backe P, et al. Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability. Sci Rep. 2017;7:15050 pubmed publisher
Elinati E, Russell H, Ojarikre O, Sangrithi M, Hirota T, de Rooij D, et al. DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line. Proc Natl Acad Sci U S A. 2017;114:12536-12541 pubmed publisher
Chanet S, Sharan R, Khan Z, Martin A. Myosin 2-Induced Mitotic Rounding Enables Columnar Epithelial Cells to Interpret Cortical Spindle Positioning Cues. Curr Biol. 2017;27:3350-3358.e3 pubmed publisher
Vassilev V, Platek A, Hiver S, Enomoto H, Takeichi M. Catenins Steer Cell Migration via Stabilization of Front-Rear Polarity. Dev Cell. 2017;43:463-479.e5 pubmed publisher
Horton J, Stefanick D, Zhao M, Janoshazi A, Gassman N, Seddon H, et al. XRCC1-mediated repair of strand breaks independent of PNKP binding. DNA Repair (Amst). 2017;60:52-63 pubmed publisher
Matsudaira T, Mukai K, Noguchi T, Hasegawa J, Hatta T, Iemura S, et al. Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells. Nat Commun. 2017;8:1246 pubmed publisher
Banerji R, Skibbens R, Iovine M. Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome. Biol Open. 2017;6:1802-1813 pubmed publisher
Sindhwani A, Arya S, Kaur H, Jagga D, Tuli A, Sharma M. Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication. PLoS Pathog. 2017;13:e1006700 pubmed publisher
Schimmel J, Kool H, van Schendel R, Tijsterman M. Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells. EMBO J. 2017;36:3634-3649 pubmed publisher
Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar A, et al. PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP. Proc Natl Acad Sci U S A. 2017;114:11944-11949 pubmed publisher
Corver W, Demmers J, Oosting J, Sahraeian S, Boot A, Ruano D, et al. ROS-induced near-homozygous genomes in thyroid cancer. Endocr Relat Cancer. 2018;25:83-97 pubmed publisher
Silva L, Poschet G, Nonnenmacher Y, Becker H, Sapcariu S, Gaupel A, et al. Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype. EMBO Rep. 2017;18:2172-2185 pubmed publisher
Martino L, Morchoisne Bolhy S, Cheerambathur D, Van Hove L, Dumont J, Joly N, et al. Channel Nucleoporins Recruit PLK-1 to Nuclear Pore Complexes to Direct Nuclear Envelope Breakdown in C. elegans. Dev Cell. 2017;43:157-171.e7 pubmed publisher
Gil K, Kim W, Lee H, Faisal M, Saquib Q, Alatar A, et al. ZEITLUPE Contributes to a Thermoresponsive Protein Quality Control System in Arabidopsis. Plant Cell. 2017;29:2882-2894 pubmed publisher
Maruyama J, Inami K, Michishita F, Jiang X, Iwasa H, Nakagawa K, et al. Novel YAP1 Activator, Identified by Transcription-Based Functional Screen, Limits Multiple Myeloma Growth. Mol Cancer Res. 2018;16:197-211 pubmed publisher
Reczek C, Birsoy K, Kong H, Martínez Reyes I, Wang T, Gao P, et al. A CRISPR screen identifies a pathway required for paraquat-induced cell death. Nat Chem Biol. 2017;13:1274-1279 pubmed publisher
Shanmugasundaram K, Nayak B, Friedrichs W, Kaushik D, Rodriguez R, Block K. NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance. Nat Commun. 2017;8:997 pubmed publisher
Leyk J, Daly C, Janssen Bienhold U, Kennedy B, Richter Landsberg C. HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness. Cell Death Dis. 2017;8:e3028 pubmed publisher
Blum J, Bonaccorsi S, Marzullo M, Palumbo V, Yamashita Y, Barbash D, et al. The Hybrid Incompatibility Genes Lhr and Hmr Are Required for Sister Chromatid Detachment During Anaphase but Not for Centromere Function. Genetics. 2017;207:1457-1472 pubmed publisher
Perico L, Morigi M, Rota C, Breno M, Mele C, Noris M, et al. Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function. Nat Commun. 2017;8:983 pubmed publisher
Bao X, Liu H, Liu X, Ruan K, Zhang Y, Zhang Z, et al. Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation. J Mol Cell Biol. 2018;10:18-32 pubmed publisher
Byrne D, Harmon M, Simpson J, Blackstone C, O Sullivan N. Roles for the VCP co-factors Npl4 and Ufd1 in neuronal function in Drosophila melanogaster. J Genet Genomics. 2017;44:493-501 pubmed publisher
Parisi L, Li N, Atilla Gokcumen G. Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis. Cell Chem Biol. 2017;24:1445-1454.e8 pubmed publisher
Bajbouj K, Shafarin J, Abdalla M, Ahmad I, Hamad M. Estrogen-induced disruption of intracellular iron metabolism leads to oxidative stress, membrane damage, and cell cycle arrest in MCF-7 cells. Tumour Biol. 2017;39:1010428317726184 pubmed publisher
Hu W, Wu F, Zhang Y, Gong C, Iqbal K, Liu F. Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis. Front Aging Neurosci. 2017;9:311 pubmed publisher
Schubert L, Ho T, Hoffmann S, Haahr P, Guérillon C, Mailand N. RADX interacts with single-stranded DNA to promote replication fork stability. EMBO Rep. 2017;18:1991-2003 pubmed publisher
Huang S, Fantini D, Merrill B, Bagchi S, Guzman G, Raychaudhuri P. DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer. Cancer Res. 2017;77:6562-6575 pubmed publisher
Nederlof R, van den Elshout M, Koeman A, Uthman L, Koning I, Eerbeek O, et al. Cyclophilin D ablation is associated with increased end-ischemic mitochondrial hexokinase activity. Sci Rep. 2017;7:12749 pubmed publisher
Kojima Y, Sasaki K, Yokobayashi S, Sakai Y, Nakamura T, Yabuta Y, et al. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Cell Stem Cell. 2017;21:517-532.e5 pubmed publisher
Singh P, Roukounakis A, Frank D, Kirschnek S, Das K, Neumann S, et al. Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis. Genes Dev. 2017;31:1754-1769 pubmed publisher
Sapir T, Levy T, Kozer N, Shin I, Zamor V, Haffner Krausz R, et al. Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases. Cereb Cortex. 2017;:1-14 pubmed publisher
Kim S, Park S, Yoo S, Rho J, Jun E, Chang S, et al. Downregulation of X-linked inhibitor of apoptosis protein by '7-Benzylidenenaltrexone maleate' sensitizes pancreatic cancer cells to TRAIL-induced apoptosis. Oncotarget. 2017;8:61057-61071 pubmed publisher
Dasgupta A, Baby N, Krishna K, Hakim M, Wong Y, Behnisch T, et al. Substance P induces plasticity and synaptic tagging/capture in rat hippocampal area CA2. Proc Natl Acad Sci U S A. 2017;114:E8741-E8749 pubmed publisher
Alvaro Blanco J, Urso K, Chiodo Y, Martín Cortázar C, Kourani O, Arco P, et al. MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter. Nucleic Acids Res. 2017;45:9960-9975 pubmed publisher
Palencia Campos A, Ullah A, Nevado J, Yildirim R, Unal E, Ciorraga M, et al. GLI1 inactivation is associated with developmental phenotypes overlapping with Ellis-van Creveld syndrome. Hum Mol Genet. 2017;26:4556-4571 pubmed publisher
Moller A, Bauer C, Cohen R, Webster C, De Vos K. Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels. Hum Mol Genet. 2017;26:4668-4679 pubmed publisher
Huang Y, Lin S, Shih H, Chou C, Chu H, Chiu C, et al. Epigenetic regulation of NOTCH1 and NOTCH3 by KMT2A inhibits glioma proliferation. Oncotarget. 2017;8:63110-63120 pubmed publisher
Schwind L, Nalbach L, Zimmer A, Kostelnik K, Menegatti J, Grässer F, et al. Quinalizarin inhibits adipogenesis through down-regulation of transcription factors and microRNA modulation. Biochim Biophys Acta Gen Subj. 2017;1861:3272-3281 pubmed publisher
McNulty D, Bonnette W, Qi H, Wang L, Ho T, Waszkiewicz A, et al. A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1. SLAS Discov. 2018;23:34-46 pubmed publisher
Brauswetter D, Gurbi B, Varga A, Varkondi E, Schwab R, Banhegyi G, et al. Molecular subtype specific efficacy of MEK inhibitors in pancreatic cancers. PLoS ONE. 2017;12:e0185687 pubmed publisher
Ogata T, Ito K, Shindo T, Hatanaka K, Eguchi K, Kurosawa R, et al. Low-intensity pulsed ultrasound enhances angiogenesis and ameliorates contractile dysfunction of pressure-overloaded heart in mice. PLoS ONE. 2017;12:e0185555 pubmed publisher
Jia T, Zhang B, You C, Zhang Y, Zeng L, Li S, et al. The Arabidopsis MOS4-Associated Complex Promotes MicroRNA Biogenesis and Precursor Messenger RNA Splicing. Plant Cell. 2017;29:2626-2643 pubmed publisher
Iwahori S, Kalejta R. Phosphorylation of transcriptional regulators in the retinoblastoma protein pathway by UL97, the viral cyclin-dependent kinase encoded by human cytomegalovirus. Virology. 2017;512:95-103 pubmed publisher
Newman L, Schiavon C, Turn R, Kahn R. The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space. Cell Logist. 2017;7:e1340104 pubmed publisher
Overlack K, Bange T, Weissmann F, Faesen A, Maffini S, Primorac I, et al. BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling. Curr Biol. 2017;27:2915-2927.e7 pubmed publisher
Isoda T, Moore A, He Z, Chandra V, Aida M, Denholtz M, et al. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017;171:103-119.e18 pubmed publisher
Wang H, Choe M, Lee I, Namgoong S, Kim J, Kim N, et al. CIP2A acts as a scaffold for CEP192-mediated microtubule organizing center assembly by recruiting Plk1 and aurora A during meiotic maturation. Development. 2017;144:3829-3839 pubmed publisher
Miyauchi H, Ohta H, Nagaoka S, Nakaki F, Sasaki K, Hayashi K, et al. Bone morphogenetic protein and retinoic acid synergistically specify female germ-cell fate in mice. EMBO J. 2017;36:3100-3119 pubmed publisher
McMillan K, Murray T, Bengoa Vergniory N, Cordero Llana O, Cooper J, Buckley A, et al. Loss of MicroRNA-7 Regulation Leads to ?-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo. Mol Ther. 2017;25:2404-2414 pubmed publisher
King A, Li L, Wong D, Liu R, Bamford R, Strasser A, et al. Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms. PLoS Genet. 2017;13:e1007010 pubmed publisher
Peña Oyarzun D, Troncoso R, Kretschmar C, Hernando C, Budini M, Morselli E, et al. Hyperosmotic stress stimulates autophagy via polycystin-2. Oncotarget. 2017;8:55984-55997 pubmed publisher
Feng W, Jasin M. BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination. Nat Commun. 2017;8:525 pubmed publisher
Andrysik Z, Galbraith M, Guarnieri A, Zaccara S, Sullivan K, Pandey A, et al. Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity. Genome Res. 2017;27:1645-1657 pubmed publisher
Živicová V, Lacina L, Mateu R, Smetana K, Kavková R, Drobná Krejčí E, et al. Analysis of dermal fibroblasts isolated from neonatal and child cleft lip and adult skin: Developmental implications on reconstructive surgery. Int J Mol Med. 2017;40:1323-1334 pubmed publisher
Trempolec N, Munoz J, Slobodnyuk K, Marin S, Cascante M, Zorzano A, et al. Induction of oxidative metabolism by the p38α/MK2 pathway. Sci Rep. 2017;7:11367 pubmed publisher
Kalfon R, Haas T, Shofti R, Moskovitz J, Schwartz O, Suss Toby E, et al. c-Jun dimerization protein 2 (JDP2) deficiency promotes cardiac hypertrophy and dysfunction in response to pressure overload. Int J Cardiol. 2017;249:357-363 pubmed publisher
Hannon C, Blythe S, Wieschaus E. Concentration dependent chromatin states induced by the bicoid morphogen gradient. elife. 2017;6: pubmed publisher
Espinosa Díez C, Miguel V, Vallejo S, Sanchez F, Sandoval E, Blanco E, et al. Role of glutathione biosynthesis in endothelial dysfunction and fibrosis. Redox Biol. 2018;14:88-99 pubmed publisher
Halaoui R, Rejon C, Chatterjee S, Szymborski J, Meterissian S, Muller W, et al. Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma. Genes Dev. 2017;31:1573-1587 pubmed publisher
Kedage V, Strittmatter B, Dausinas P, Hollenhorst P. Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation. J Biol Chem. 2017;292:17225-17235 pubmed publisher
Wu J, Ao M, Shao R, Wang H, Yu D, Fang M, et al. A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter. Sci Rep. 2017;7:10657 pubmed publisher
Godbole A, Lyga S, Lohse M, Calebiro D. Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription. Nat Commun. 2017;8:443 pubmed publisher
Wood M, Ishiyama N, Singaram I, Chung C, Flozak A, Yemelyanov A, et al. α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion. J Cell Biol. 2017;216:3767-3783 pubmed publisher
Campbell A, Oliva J, Yates M, Zhong J, Shadle S, Snider L, et al. BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells. Skelet Muscle. 2017;7:16 pubmed publisher
Ivanova I, Much C, Di Giacomo M, Azzi C, Morgan M, Moreira P, et al. The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence. Mol Cell. 2017;67:1059-1067.e4 pubmed publisher
Huber S, Theiler R, de Quervain D, Wiens O, Karangenc T, Heussler V, et al. The Microtubule-Stabilizing Protein CLASP1 Associates with the Theileria annulata Schizont Surface via Its Kinetochore-Binding Domain. mSphere. 2017;2: pubmed publisher
Cuninghame S, Jackson R, Lees S, Zehbe I. Two common variants of human papillomavirus type 16 E6 differentially deregulate sugar metabolism and hypoxia signalling in permissive human keratinocytes. J Gen Virol. 2017;98:2310-2319 pubmed publisher
Fiuza M, Rostosky C, Parkinson G, Bygrave A, Halemani N, Baptista M, et al. PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin. J Cell Biol. 2017;216:3323-3338 pubmed publisher
Barrott J, Zhu J, Smith Fry K, Susko A, Nollner D, Burrell L, et al. The Influential Role of BCL2 Family Members in Synovial Sarcomagenesis. Mol Cancer Res. 2017;15:1733-1740 pubmed publisher
Pacheco A, Aguayo F, Aliaga E, Munoz M, García Rojo G, Olave F, et al. Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats. Front Mol Neurosci. 2017;10:244 pubmed publisher
Geng J, Ito Y, Shi L, Amin P, Chu J, Ouchida A, et al. Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis. Nat Commun. 2017;8:359 pubmed publisher
Schmuckli Maurer J, Reber V, Wacker R, Bindschedler A, Zakher A, Heussler V. Inverted recruitment of autophagy proteins to the Plasmodium berghei parasitophorous vacuole membrane. PLoS ONE. 2017;12:e0183797 pubmed publisher
Samwer M, Schneider M, Hoefler R, Schmalhorst P, Jude J, Zuber J, et al. DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes. Cell. 2017;170:956-972.e23 pubmed publisher
Edenharter O, Clement J, Schneuwly S, Navarro J. Overexpression of Drosophila frataxin triggers cell death in an iron-dependent manner. J Neurogenet. 2017;31:189-202 pubmed publisher
Hashwah H, Schmid C, Kasser S, Bertram K, Stelling A, Manz M, et al. Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth. Proc Natl Acad Sci U S A. 2017;114:9701-9706 pubmed publisher
Koo C, Giacomini C, Reyes Corral M, Olmos Y, Tavares I, Marson C, et al. Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells. Mol Cancer Ther. 2017;16:2410-2421 pubmed publisher
Beaufils F, Cmiljanovic N, Cmiljanovic V, Bohnacker T, Melone A, Marone R, et al. 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology. J Med Chem. 2017;60:7524-7538 pubmed publisher
Winter E, Schwarz A, Fabig G, Feldman J, Pires daSilva A, Müller Reichert T, et al. Cytoskeletal variations in an asymmetric cell division support diversity in nematode sperm size and sex ratios. Development. 2017;144:3253-3263 pubmed publisher
Shinjo S, Jiang S, Nameta M, Suzuki T, Kanai M, Nomura Y, et al. Disruption of the mitochondria-associated ER membrane (MAM) plays a central role in palmitic acid-induced insulin resistance. Exp Cell Res. 2017;359:86-93 pubmed publisher
Fukai Y, Ohsawa Y, Ohtsubo H, Nishimatsu S, Hagiwara H, Noda M, et al. Cleavage of ?-dystroglycan occurs in sarcoglycan-deficient skeletal muscle without MMP-2 and MMP-9. Biochem Biophys Res Commun. 2017;492:199-205 pubmed publisher
Cutler S, Doecke J, Ghazawi I, Yang J, Griffiths L, Spring K, et al. Novel STAT binding elements mediate IL-6 regulation of MMP-1 and MMP-3. Sci Rep. 2017;7:8526 pubmed publisher
Bailey K, Haj F, Simon S, Passerini A. Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation. Sci Rep. 2017;7:8196 pubmed publisher
Bainor A, Deng F, Wang Y, Lee P, Cantor D, Logan S, et al. Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence. Cancer Res. 2017;77:5339-5348 pubmed publisher
Li Y, Wang C, Cai W, Sengupta S, Zavortink M, Deng H, et al. H2Av facilitates H3S10 phosphorylation but is not required for heat shock-induced chromatin decondensation or transcriptional elongation. Development. 2017;144:3232-3240 pubmed publisher
Chavali S, Chavali P, Chalancon G, de Groot N, Gemayel R, Latysheva N, et al. Constraints and consequences of the emergence of amino acid repeats in eukaryotic proteins. Nat Struct Mol Biol. 2017;24:765-777 pubmed publisher
di Pietro F, Valon L, Li Y, Goïame R, Genovesio A, Morin X. An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z ? as an Essential Regulator of Spindle Orientation. Curr Biol. 2017;27:2452-2464.e8 pubmed publisher
Morgan M, Much C, DiGiacomo M, Azzi C, Ivanova I, Vitsios D, et al. mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome. Nature. 2017;548:347-351 pubmed publisher
Tyc K, Nabih A, Wu M, Wedeles C, Sobotka J, Claycomb J. The Conserved Intron Binding Protein EMB-4 Plays Differential Roles in Germline Small RNA Pathways of C. elegans. Dev Cell. 2017;42:256-270.e6 pubmed publisher
Chen H, Chin Y, Lundy D, Liang C, Chi Y, Kuo P, et al. Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis. Sci Rep. 2017;7:7372 pubmed publisher
Mayor Ruiz C, Dominguez O, Fernandez Capetillo O. TrapSeq: An RNA Sequencing-Based Pipeline for the Identification of Gene-Trap Insertions in Mammalian Cells. J Mol Biol. 2017;429:2780-2789 pubmed publisher
Rodriguez J, Peglion F, Martin J, Hubatsch L, Reich J, Hirani N, et al. aPKC Cycles between Functionally Distinct PAR Protein Assemblies to Drive Cell Polarity. Dev Cell. 2017;42:400-415.e9 pubmed publisher
Mans L, Querol Cano L, van Pelt J, Giardoglou P, Keune W, Haramis A. The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress. Sci Rep. 2017;7:7327 pubmed publisher
Hennig M, Fiedler S, Jux C, Thierfelder L, Drenckhahn J. Prenatal Mechanistic Target of Rapamycin Complex 1 (m TORC1) Inhibition by Rapamycin Treatment of Pregnant Mice Causes Intrauterine Growth Restriction and Alters Postnatal Cardiac Growth, Morphology, and Function. J Am Heart Assoc. 2017;6: pubmed publisher
Martin J, Julovi S, Lin M, de Silva H, Boyle F, Baxter R. Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade. Breast Cancer Res. 2017;19:90 pubmed publisher
Han Y, Xiong Y, Shi X, Wu J, Zhao Y, Jiang J. Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-?2 nuclear import system. PLoS Biol. 2017;15:e2002063 pubmed publisher
Chaudhari S, Kipreos E. Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways. Nat Commun. 2017;8:182 pubmed publisher
Perroud J, Bernheim L, Frieden M, Koenig S. Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells. J Cell Sci. 2017;130:3083-3093 pubmed publisher
Perdiz D, Lorin S, Leroy Gori I, Poüs C. Stress-induced hyperacetylation of microtubule enhances mitochondrial fission and modulates the phosphorylation of Drp1 at 616Ser. Cell Signal. 2017;39:32-43 pubmed publisher
Ambady P, Wu Y, Walker J, Kersch C, Pagel M, Woltjer R, et al. Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors. Cancer Gene Ther. 2017;24:348-357 pubmed publisher
Butterfield N, Qian C, Logan M. Pitx1 determines characteristic hindlimb morphologies in cartilage micromass culture. PLoS ONE. 2017;12:e0180453 pubmed publisher
Sharma A, Bendre A, Mondal A, Muzumdar D, Goel N, Shiras A. Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma. Front Oncol. 2017;7:146 pubmed publisher
Estravís M, Rincón S, Portales E, Perez P, Santos B. Cdc42 activation state affects its localization and protein levels in fission yeast. Microbiology. 2017;163:1156-1166 pubmed publisher
Wang J, Huo B, Liu W, Li D, Liao L. Abnormal meiosis in an intersectional allotriploid of Populus L. and segregation of ploidy levels in 2x × 3x progeny. PLoS ONE. 2017;12:e0181767 pubmed publisher
Takeuchi H, Yu H, Hao H, Takeuchi M, Ito A, Li H, et al. O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking. J Biol Chem. 2017;292:15964-15973 pubmed publisher
Zieba B, Henry L, Lacroix M, Jemaà M, Lavabre Bertrand T, Meunier L, et al. The proteasome maturation protein POMP increases proteasome assembly and activity in psoriatic lesional skin. J Dermatol Sci. 2017;88:10-19 pubmed publisher
Roy D, Farabaugh K, Wu J, Charrier A, SMAS C, Hatzoglou M, et al. Coordinated transcriptional control of adipocyte triglyceride lipase (Atgl) by transcription factors Sp1 and peroxisome proliferator-activated receptor ? (PPAR?) during adipocyte differentiation. J Biol Chem. 2017;292:14827-14835 pubmed publisher
Hayashi S, Inoue Y, Hattori S, Kaneko M, Shioi G, Miyakawa T, et al. Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice. Sci Rep. 2017;7:5801 pubmed publisher
Vosnakis N, Koch M, Scheer E, Kessler P, Mely Y, Didier P, et al. Coactivators and general transcription factors have two distinct dynamic populations dependent on transcription. EMBO J. 2017;36:2710-2725 pubmed publisher
Zhang Z, Meszaros G, He W, Xu Y, de Fatima Magliarelli H, Mailly L, et al. Protein kinase D at the Golgi controls NLRP3 inflammasome activation. J Exp Med. 2017;214:2671-2693 pubmed publisher
Gehrig S, Macpherson J, Driscoll P, Symon A, Martin S, Macrae J, et al. An engineered photoswitchable mammalian pyruvate kinase. FEBS J. 2017;284:2955-2980 pubmed publisher
Tsankova A, Pham T, Garcia D, Otte F, Cabernard C. Cell Polarity Regulates Biased Myosin Activity and Dynamics during Asymmetric Cell Division via Drosophila Rho Kinase and Protein Kinase N. Dev Cell. 2017;42:143-155.e5 pubmed publisher
Chen C, Avdievich E, Zhang Y, Zhang Y, Wei K, Lee K, et al. EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells. DNA Repair (Amst). 2017;57:98-106 pubmed publisher
Ryazantseva M, Goncharova A, Skobeleva K, Erokhin M, Methner A, Georgiev P, et al. Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons. Mol Neurobiol. 2018;55:4667-4680 pubmed publisher
Yoon S, Kawasaki I, Shim Y. The B-type cyclin CYB-1 maintains the proper position and number of centrosomes during spermatogenesis in Caenorhabditis elegans. J Cell Sci. 2017;130:2722-2735 pubmed publisher
Shutova M, Asokan S, Talwar S, Assoian R, Bear J, Svitkina T. Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility. J Cell Biol. 2017;216:2877-2889 pubmed publisher
Westerlund I, Shi Y, Toskas K, Fell S, Li S, Surova O, et al. Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression. Proc Natl Acad Sci U S A. 2017;114:E6137-E6146 pubmed publisher
Okuda K, Kobayashi S, Fukaya M, Watanabe A, Murakami T, Hagiwara M, et al. CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility. Neurobiol Dis. 2017;106:158-170 pubmed publisher
Testoni G, Duran J, García Rocha M, Vilaplana F, Serrano A, Sebastián D, et al. Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment. Cell Metab. 2017;26:256-266.e4 pubmed publisher
Neukomm L, Burdett T, Seeds A, Hampel S, Coutinho Budd J, Farley J, et al. Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly. Neuron. 2017;95:78-91.e5 pubmed publisher
Kobayashi R, Kato A, Sagara H, Watanabe M, Maruzuru Y, Koyanagi N, et al. Herpes Simplex Virus 1 Small Capsomere-Interacting Protein VP26 Regulates Nucleocapsid Maturation. J Virol. 2017;91: pubmed publisher
Murakami S, Suzuki T, Harigae H, Romeo P, Yamamoto M, Motohashi H. NRF2 Activation Impairs Quiescence and Bone Marrow Reconstitution Capacity of Hematopoietic Stem Cells. Mol Cell Biol. 2017;37: pubmed publisher
Hart K, Tan J, Siemers K, Sim J, PRUITT B, Nelson W, et al. E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape. Proc Natl Acad Sci U S A. 2017;114:E5845-E5853 pubmed publisher
Litvak Y, Sharon S, Hyams M, Zhang L, Kobi S, Katsowich N, et al. Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-?B signaling pathway. PLoS Pathog. 2017;13:e1006472 pubmed publisher
Khan K, Naylor A, Khan A, Noy P, Mambretti M, Lodhia P, et al. Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface. Oncogene. 2017;36:6097-6108 pubmed publisher
Zhang Z, Kang S, Liu X, Ahn E, Zhang Z, He L, et al. Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease. Nat Struct Mol Biol. 2017;24:632-642 pubmed publisher
Feng Q, Jagannathan S, Bradley R. The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity. Mol Cell. 2017;67:239-251.e6 pubmed publisher
Chen J, Buchwalter R, Kao L, Megraw T. A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers. Curr Biol. 2017;27:1928-1940.e6 pubmed publisher
Rha J, Jones S, Fidler J, Banerjee A, Leung S, Morris K, et al. The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice. Hum Mol Genet. 2017;26:3663-3681 pubmed publisher
Liebl D, Qi X, Zhe Y, Barnett T, Teasdale R. SopB-Mediated Recruitment of SNX18 Facilitates Salmonella Typhimurium Internalization by the Host Cell. Front Cell Infect Microbiol. 2017;7:257 pubmed publisher
Tang T, Scambler T, Smallie T, Cunliffe H, Ross E, Rosner D, et al. Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E2, dual specificity phosphatase 1 and tristetraprolin. Sci Rep. 2017;7:4350 pubmed publisher
Laviolette L, Mermoud J, Calvo I, Olson N, Boukhali M, Steinlein O, et al. Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein. Nat Commun. 2017;8:15866 pubmed publisher
Zhao H, Gulesserian S, Ganesan S, Ou J, Morrison K, Zeng Z, et al. Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC-induced Thrombocytopenia. Mol Cancer Ther. 2017;16:1877-1886 pubmed publisher
Yanatori I, Richardson D, Toyokuni S, Kishi F. The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer. J Biol Chem. 2017;292:13205-13229 pubmed publisher
Freire A, Alves C, Goes G, Resende B, Moretti N, Nunes V, et al. Catalase expression impairs oxidative stress-mediated signalling in Trypanosoma cruzi. Parasitology. 2017;144:1498-1510 pubmed publisher
Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, et al. Discovery of long-range inhibitory signaling to ensure single axon formation. Nat Commun. 2017;8:33 pubmed publisher
Liu R, King A, Hoch N, Chang C, Kelly G, Deans A, et al. ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress. DNA Repair (Amst). 2017;57:29-34 pubmed publisher
Wang C, Li Z, Shao F, Yang X, Feng X, Shi S, et al. High expression of Collagen Triple Helix Repeat Containing 1 (CTHRC1) facilitates progression of oesophageal squamous cell carcinoma through MAPK/MEK/ERK/FRA-1 activation. J Exp Clin Cancer Res. 2017;36:84 pubmed publisher
Renault Mihara F, Mukaino M, Shinozaki M, Kumamaru H, Kawase S, Baudoux M, et al. Regulation of RhoA by STAT3 coordinates glial scar formation. J Cell Biol. 2017;216:2533-2550 pubmed publisher
Nakamura F, Okada T, Shishikura M, Uetani N, Taniguchi M, Yagi T, et al. Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase. J Neurosci. 2017;37:7125-7139 pubmed publisher
Birendra Kc -, May D, Benson B, Kim D, Shivega W, Ali M, et al. VRK2A is an A-type lamin-dependent nuclear envelope kinase that phosphorylates BAF. Mol Biol Cell. 2017;28:2241-2250 pubmed publisher
Liu X, Zeng K, Li M, Wang Q, Liu R, Zhang B, et al. Expression of P301L-hTau in mouse MEC induces hippocampus-dependent memory deficit. Sci Rep. 2017;7:3914 pubmed publisher
Ali A, Veeranki S, Chinchole A, Tyagi S. MLL/WDR5 Complex Regulates Kif2A Localization to Ensure Chromosome Congression and Proper Spindle Assembly during Mitosis. Dev Cell. 2017;41:605-622.e7 pubmed publisher
Iaconelli J, Lalonde J, Watmuff B, Liu B, Mazitschek R, Haggarty S, et al. Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells. ACS Chem Biol. 2017;12:2139-2148 pubmed publisher
Lim N, Shohayeb B, Zaytseva O, Mitchell N, Millard S, Ng D, et al. Glial-Specific Functions of Microcephaly Protein WDR62 and Interaction with the Mitotic Kinase AURKA Are Essential for Drosophila Brain Growth. Stem Cell Reports. 2017;9:32-41 pubmed publisher
Li X, Han G, Li X, Kan Q, Fan Z, Li Y, et al. Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells. Oncotarget. 2017;8:46363-46380 pubmed publisher
Schleich S, Acevedo J, Clemm von Hohenberg K, Teleman A. Identification of transcripts with short stuORFs as targets for DENR•MCTS1-dependent translation in human cells. Sci Rep. 2017;7:3722 pubmed publisher
Weis S, Carlos A, Moita M, Singh S, Blankenhaus B, Cardoso S, et al. Metabolic Adaptation Establishes Disease Tolerance to Sepsis. Cell. 2017;169:1263-1275.e14 pubmed publisher
Leymarie O, Meyer L, Tafforeau L, Lotteau V, Costa B, Delmas B, et al. Influenza virus protein PB1-F2 interacts with CALCOCO2 (NDP52) to modulate innate immune response. J Gen Virol. 2017;98:1196-1208 pubmed publisher
Zaidi S, Perez A, White E, Lian J, Stein J, Stein G. An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells. Oncotarget. 2017;8:39994-40005 pubmed publisher
Agrawal P, Fontanals Cirera B, Sokolova E, Jacob S, Vaiana C, Argibay D, et al. A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis. Cancer Cell. 2017;31:804-819.e7 pubmed publisher
Wang H, Nicolay B, Chick J, Gao X, Geng Y, Ren H, et al. The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival. Nature. 2017;546:426-430 pubmed publisher
Mu P, Akashi T, Lu F, Kishida S, Kadomatsu K. A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma. Oncogene. 2017;36:5745-5756 pubmed publisher
McArthur K, Fetcho J. Key Features of Structural and Functional Organization of Zebrafish Facial Motor Neurons Are Resilient to Disruption of Neuronal Migration. Curr Biol. 2017;27:1746-1756.e5 pubmed publisher
Ogushi S, Yamagata K, Obuse C, Furuta K, Wakayama T, Matzuk M, et al. Reconstitution of the oocyte nucleolus in mice through a single nucleolar protein, NPM2. J Cell Sci. 2017;130:2416-2429 pubmed publisher
Modica G, Skorobogata O, Sauvageau E, Vissa A, Yip C, Kim P, et al. Rab7 palmitoylation is required for efficient endosome-to-TGN trafficking. J Cell Sci. 2017;130:2579-2590 pubmed publisher
Kim C, Tambe Y, Mukaisho K, Sugihara H, Kageyama S, Kawauchi A, et al. Periostin suppresses in vivo invasiveness via PDK1/Akt/mTOR signaling pathway in a mouse orthotopic model of bladder cancer. Oncol Lett. 2017;13:4276-4284 pubmed publisher
Guo L, Allu P, Zandarashvili L, McKinley K, Sekulic N, Dawicki McKenna J, et al. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nat Commun. 2017;8:15775 pubmed publisher
Lismont C, Nordgren M, Brees C, Knoops B, Van Veldhoven P, Fransen M. Peroxisomes as Modulators of Cellular Protein Thiol Oxidation: A New Model System. Antioxid Redox Signal. 2017;: pubmed publisher
Wang A, Carraro Lacroix L, Owen C, Gao B, Corey P, Tyrrell P, et al. Activity-independent targeting of mTOR to lysosomes in primary osteoclasts. Sci Rep. 2017;7:3005 pubmed publisher
Meng H, Yamashita C, Shiba Fukushima K, Inoshita T, Funayama M, Sato S, et al. Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c. Nat Commun. 2017;8:15500 pubmed publisher
Ren J, Li J, Feng Y, Shu B, Gui Y, Wei W, et al. Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis. J Pathol. 2017;242:488-499 pubmed publisher
Saj A, Chatterjee S, Zhu B, Cukuroglu E, Gocha T, Zhang X, et al. Disrupting Interactions Between β-Catenin and Activating TCFs Reconstitutes Ground State Pluripotency in Mouse Embryonic Stem Cells. Stem Cells. 2017;35:1924-1933 pubmed publisher
Atherton P, Lausecker F, Harrison A, Ballestrem C. Low-intensity pulsed ultrasound promotes cell motility through vinculin-controlled Rac1 GTPase activity. J Cell Sci. 2017;130:2277-2291 pubmed publisher
Erustes A, Stefani F, Terashima J, Stilhano R, Monteforte P, da Silva Pereira G, et al. Overexpression of α-synuclein in an astrocyte cell line promotes autophagy inhibition and apoptosis. J Neurosci Res. 2018;96:160-171 pubmed publisher
Tiedemann K, Le Nihouannen D, Fong J, Hussein O, Barralet J, Komarova S. Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt. Front Cell Dev Biol. 2017;5:54 pubmed publisher
Del Collado M, da Silveira J, Sangalli J, Andrade G, Sousa L, Silva L, et al. Fatty Acid Binding Protein 3 And Transzonal Projections Are Involved In Lipid Accumulation During In Vitro Maturation Of Bovine Oocytes. Sci Rep. 2017;7:2645 pubmed publisher
Shi Y, Ping Y, Zhou W, He Z, Chen C, Bian B, et al. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth. Nat Commun. 2017;8:15080 pubmed publisher
Wang C, Hong Y, Syu J, Tsai Y, Liu X, Chen T, et al. LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells. J Cell Biochem. 2018;119:314-326 pubmed publisher
Xu X, Yokoyama S, Hayakawa Y, Saiki I. Coptidis Rhizoma induces intrinsic apoptosis through BAX and BAK activation in human melanoma. Oncol Rep. 2017;38:538-544 pubmed publisher
He Y, Zhu W, Shin M, Gary J, Liu C, DuBois W, et al. cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma. Stem Cell Reports. 2017;8:1630-1644 pubmed publisher
Killilea A, Csencsits R, Le E, Patel A, Kenny S, Xu K, et al. Cytoskeletal organization in microtentacles. Exp Cell Res. 2017;357:291-298 pubmed publisher
Louis Sam Titus A, Yusuff T, Cassar M, Thomas E, Kretzschmar D, D Mello S. Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease. J Neurosci. 2017;37:6575-6587 pubmed publisher
Kruse R, Krantz J, Barker N, Coletta R, Rafikov R, Luo M, et al. Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein. Mol Cell Proteomics. 2017;16:1718-1735 pubmed publisher
Tonucci F, Ferretti A, Almada E, Cribb P, Vena R, Hidalgo F, et al. Microtubules regulate brush border formation. J Cell Physiol. 2018;233:1468-1480 pubmed publisher
Joy M, Gau D, Castellucci N, Prywes R, Roy P. The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms. J Biol Chem. 2017;292:11777-11791 pubmed publisher
Lang F, Aravamudhan S, Nolte H, Türk C, Hölper S, Muller S, et al. Dynamic changes in the mouse skeletal muscle proteome during denervation-induced atrophy. Dis Model Mech. 2017;10:881-896 pubmed publisher
Dilley K, Nikolaitchik O, Galli A, Burdick R, LEVINE L, Li K, et al. Interactions between HIV-1 Gag and Viral RNA Genome Enhance Virion Assembly. J Virol. 2017;91: pubmed publisher
Shirnekhi H, Kelley E, DeLuca J, Herman J. Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation. Mol Biol Cell. 2017;28:2035-2041 pubmed publisher
Barbazán J, Alonso Alconada L, Elkhatib N, Geraldo S, Gurchenkov V, Glentis A, et al. Liver Metastasis Is Facilitated by the Adherence of Circulating Tumor Cells to Vascular Fibronectin Deposits. Cancer Res. 2017;77:3431-3441 pubmed publisher
Stroud M, Feng W, Zhang J, Veevers J, Fang X, Gerace L, et al. Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle. J Cell Biol. 2017;216:1915-1924 pubmed publisher
Bae S, Lee M, Mun S, Giannopoulou E, Yong Gonzalez V, Cross J, et al. MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERR?. J Clin Invest. 2017;127:2555-2568 pubmed publisher
Petris G, Casini A, Montagna C, Lorenzin F, Prandi D, Romanel A, et al. Hit and go CAS9 delivered through a lentiviral based self-limiting circuit. Nat Commun. 2017;8:15334 pubmed publisher
Kelkar M, Thakur B, Derle A, Chatterjee S, Ray P, De A. Tumor suppressor protein p53 exerts negative transcriptional regulation on human sodium iodide symporter gene expression in breast cancer. Breast Cancer Res Treat. 2017;164:603-615 pubmed publisher
Amit U, Kain D, Wagner A, Sahu A, Nevo Caspi Y, Gonen N, et al. New Role for Interleukin-13 Receptor α1 in Myocardial Homeostasis and Heart Failure. J Am Heart Assoc. 2017;6: pubmed publisher
Rincón E, Cejalvo T, Kanojia D, Alfranca A, Rodríguez Milla M, Gil Hoyos R, et al. Mesenchymal stem cell carriers enhance antitumor efficacy of oncolytic adenoviruses in an immunocompetent mouse model. Oncotarget. 2017;8:45415-45431 pubmed publisher
Eritja N, Felip I, Dosil M, Vigezzi L, Mirantes C, Yeramian A, et al. A Smad3-PTEN regulatory loop controls proliferation and apoptotic responses to TGF-? in mouse endometrium. Cell Death Differ. 2017;24:1443-1458 pubmed publisher
Passmore J, Pinho S, Gomez Lazaro M, Schrader M. The respiratory chain inhibitor rotenone affects peroxisomal dynamics via its microtubule-destabilising activity. Histochem Cell Biol. 2017;148:331-341 pubmed publisher
Bohlen C, Bennett F, Tucker A, Collins H, Mulinyawe S, Barres B. Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures. Neuron. 2017;94:759-773.e8 pubmed publisher
Cheng X, Liu G, Ke W, Zhao L, Lv B, Ma X, et al. Building a multipurpose insertional mutant library for forward and reverse genetics in Chlamydomonas. Plant Methods. 2017;13:36 pubmed publisher
Veß A, Blache U, Leitner L, Kurz A, Ehrenpfordt A, Sixt M, et al. A dual phenotype of MDA-MB-468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. J Cell Sci. 2017;130:2172-2184 pubmed publisher
Takahashi A, Okada R, Nagao K, Kawamata Y, Hanyu A, Yoshimoto S, et al. Exosomes maintain cellular homeostasis by excreting harmful DNA from cells. Nat Commun. 2017;8:15287 pubmed publisher
Suzuki T, Murakami S, Biswal S, Sakaguchi S, Harigae H, Yamamoto M, et al. Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice. Mol Cell Biol. 2017;37: pubmed publisher
Anso E, Weinberg S, Diebold L, Thompson B, Malinge S, Schumacker P, et al. The mitochondrial respiratory chain is essential for haematopoietic stem cell function. Nat Cell Biol. 2017;19:614-625 pubmed publisher
Donati G, Rognoni E, Hiratsuka T, Liakath Ali K, Hoste E, Kar G, et al. Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties. Nat Cell Biol. 2017;19:603-613 pubmed publisher
Ebner F, Sedlyarov V, Tasciyan S, Ivin M, Kratochvill F, Gratz N, et al. The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection. J Clin Invest. 2017;127:2051-2065 pubmed publisher
Ni W, Xu S, González Grandío E, Chalkley R, Huhmer A, Burlingame A, et al. PPKs mediate direct signal transfer from phytochrome photoreceptors to transcription factor PIF3. Nat Commun. 2017;8:15236 pubmed publisher
Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed publisher
Spampinato S, Merlo S, Sano Y, Kanda T, Sortino M. Astrocytes contribute to Aβ-induced blood-brain barrier damage through activation of endothelial MMP9. J Neurochem. 2017;142:464-477 pubmed publisher
Tabaja N, Yuan Z, Oswald F, Kovall R. Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes. J Biol Chem. 2017;292:10549-10563 pubmed publisher
Kolb T, Kraxner J, Skodzek K, Haug M, Crawford D, Maaß K, et al. Optomechanical measurement of the role of lamins in whole cell deformability. J Biophotonics. 2017;10:1657-1664 pubmed publisher
Tomankova S, Abaffy P, Sindelka R. The role of nitric oxide during embryonic epidermis development of Xenopus laevis. Biol Open. 2017;6:862-871 pubmed publisher
Zhang Q, Sivakumar S, Chen Y, Gao H, Yang L, Yuan Z, et al. Ska3 Phosphorylated by Cdk1 Binds Ndc80 and Recruits Ska to Kinetochores to Promote Mitotic Progression. Curr Biol. 2017;27:1477-1484.e4 pubmed publisher
Suzawa M, Noguchi K, Nishi K, Kozuka Hata H, Oyama M, Ui Tei K. Comprehensive Identification of Nuclear and Cytoplasmic TNRC6A-Associating Proteins. J Mol Biol. 2017;429:3319-3333 pubmed publisher
Piskadlo E, Tavares A, Oliveira R. Metaphase chromosome structure is dynamically maintained by condensin I-directed DNA (de)catenation. elife. 2017;6: pubmed publisher
Sinturel F, Gerber A, Mauvoisin D, Wang J, Gatfield D, Stubblefield J, et al. Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles. Cell. 2017;169:651-663.e14 pubmed publisher
Griesing S, Kajino T, Tai M, Liu Z, Nakatochi M, Shimada Y, et al. Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells. Cancer Sci. 2017;108:1394-1404 pubmed publisher
Morris E, Kawamura E, Gillespie J, Balgi A, Kannan N, Muller W, et al. Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1. Nat Commun. 2017;8:15289 pubmed publisher
Fritz Laylin L, Lord S, Mullins R. WASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motility. J Cell Biol. 2017;216:1673-1688 pubmed publisher
Lu W, Rettenmeier E, Paszek M, Yueh M, Tukey R, Trottier J, et al. Crypt Organoid Culture as an in Vitro Model in Drug Metabolism and Cytotoxicity Studies. Drug Metab Dispos. 2017;45:748-754 pubmed publisher
Marranci A, Jiang Z, Vitiello M, Guzzolino E, Comelli L, Sarti S, et al. The landscape of BRAF transcript and protein variants in human cancer. Mol Cancer. 2017;16:85 pubmed publisher
Moretton A, Morel F, Macao B, Lachaume P, Ishak L, Lefebvre M, et al. Selective mitochondrial DNA degradation following double-strand breaks. PLoS ONE. 2017;12:e0176795 pubmed publisher
Eshelman M, Shah M, Raup Konsavage W, Rennoll S, Yochum G. TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells. Biochem Biophys Res Commun. 2017;487:716-722 pubmed publisher
Frank S, Berger P, Ljungman M, Miranti C. Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC. J Cell Sci. 2017;130:1952-1964 pubmed publisher
Seo M, Choi C, McIntyre R, Cho H, Lee C, Mansur R, et al. Effects of escitalopram and paroxetine on mTORC1 signaling in the rat hippocampus under chronic restraint stress. BMC Neurosci. 2017;18:39 pubmed publisher
Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed publisher
Jasoliya M, McMackin M, Henderson C, Perlman S, Cortopassi G. Frataxin deficiency impairs mitochondrial biogenesis in cells, mice and humans. Hum Mol Genet. 2017;26:2627-2633 pubmed publisher
Sánchez Carranza J, Alvarez L, Marquina Bahena S, Salas Vidal E, Cuevas V, Jiménez E, et al. Phenolic Compounds Isolated from Caesalpinia coriaria Induce S and G2/M Phase Cell Cycle Arrest Differentially and Trigger Cell Death by Interfering with Microtubule Dynamics in Cancer Cell Lines. Molecules. 2017;22: pubmed publisher
Bradshaw N, Yerabham A, Marreiros R, Zhang T, Nagel Steger L, Korth C. An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure. J Biol Chem. 2017;292:9583-9598 pubmed publisher
Ngan E, Stoletov K, Smith H, Common J, Muller W, Lewis J, et al. LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis. Nat Commun. 2017;8:15059 pubmed publisher
Yoon J, Lee K, Oh G, Kim G, Kim S. Regulation of Nampt expression by transcriptional coactivator NCOA6 in pancreatic ?-cells. Biochem Biophys Res Commun. 2017;487:600-606 pubmed publisher
Eun S, Feng L, Cedeno Rosario L, Gan Q, Wei G, Cui K, et al. Polycomb Group Gene E(z) Is Required for Spermatogonial Dedifferentiation in Drosophila Adult Testis. J Mol Biol. 2017;429:2030-2041 pubmed publisher
Whitaker W, Shepherd E, Sonnenburg J. Tunable Expression Tools Enable Single-Cell Strain Distinction in the Gut Microbiome. Cell. 2017;169:538-546.e12 pubmed publisher
Tawo R, Pokrzywa W, Kevei E, Akyuz M, Balaji V, Adrian S, et al. The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. Cell. 2017;169:470-482.e13 pubmed publisher
Thapaliya E, Zhang Y, Dhakal P, Brown A, Wilson J, Collins K, et al. Bioimaging with Macromolecular Probes Incorporating Multiple BODIPY Fluorophores. Bioconjug Chem. 2017;28:1519-1528 pubmed publisher
Peng L, Linghu R, Chen D, Yang J, Kou X, Wang X, et al. Inhibition of glutathione metabolism attenuates esophageal cancer progression. Exp Mol Med. 2017;49:e318 pubmed publisher
Shapira S, Lim H, Rajakumari S, Sakers A, Ishibashi J, Harms M, et al. EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex. Genes Dev. 2017;31:660-673 pubmed publisher
Do Monte F, Minier Toribio A, Quiñones Laracuente K, Medina Colón E, Quirk G. Thalamic Regulation of Sucrose Seeking during Unexpected Reward Omission. Neuron. 2017;94:388-400.e4 pubmed publisher
Wakim J, Goudenège D, Perrot R, Gueguen N, Desquiret Dumas V, Chao De La Barca J, et al. CLUH couples mitochondrial distribution to the energetic and metabolic status. J Cell Sci. 2017;130:1940-1951 pubmed publisher
Rabinowicz N, Mangala L, Brown K, Checa Rodríguez C, Castiel A, Moskovich O, et al. Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer. Oncotarget. 2017;8:27380-27392 pubmed publisher
Gasri Plotnitsky L, Ovadia A, Shamalov K, Nizri Megnaji T, Meir S, Zurer I, et al. A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity. Oncotarget. 2017;8:23775-23786 pubmed publisher
Tang H, Leung L, Saturno G, Viros A, Smith D, Di Leva G, et al. Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface. Nat Commun. 2017;8:14909 pubmed publisher
Diamantopoulou Z, White G, Fadlullah M, Dreger M, Pickering K, Maltas J, et al. TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells. Cancer Cell. 2017;31:621-634.e6 pubmed publisher
Vecchio G, Parascandolo A, Allocca C, Ugolini C, Basolo F, Moracci M, et al. Human a-L-fucosidase-1 attenuates the invasive properties of thyroid cancer. Oncotarget. 2017;8:27075-27092 pubmed publisher
Ilic N, Birsoy K, Aguirre A, Kory N, Pacold M, Singh S, et al. PIK3CA mutant tumors depend on oxoglutarate dehydrogenase. Proc Natl Acad Sci U S A. 2017;114:E3434-E3443 pubmed publisher
Piwowarczyk K, Paw M, Ryszawy D, Rutkowska Zapała M, Madeja Z, Siedlar M, et al. Connexin43high prostate cancer cells induce endothelial connexin43 up-regulation through the activation of intercellular ERK1/2-dependent signaling axis. Eur J Cell Biol. 2017;96:337-346 pubmed publisher
Huhn S, Liu J, Ye C, Lu H, Jiang X, Feng X, et al. Regulation of spindle integrity and mitotic fidelity by BCCIP. Oncogene. 2017;36:4750-4766 pubmed publisher
Singh S, Vaughan C, Frum R, Grossman S, Deb S, Palit Deb S. Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication. J Clin Invest. 2017;127:1839-1855 pubmed publisher
Xiao Z, Gaertner S, Morresi Hauf A, Genzel R, Duell T, Ullrich A, et al. Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients. Neoplasia. 2017;19:385-395 pubmed publisher
Breznau E, Murt M, Blasius T, Verhey K, Miller A. The MgcRacGAP SxIP motif tethers Centralspindlin to microtubule plus ends in Xenopus laevis. J Cell Sci. 2017;130:1809-1821 pubmed publisher
Gasset Rosa F, Chillon Marinas C, Goginashvili A, Atwal R, Artates J, Tabet R, et al. Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport. Neuron. 2017;94:48-57.e4 pubmed publisher
Brose L, Crest J, Tao L, Sullivan W. Polo kinase mediates the phosphorylation and cellular localization of Nuf/FIP3, a Rab11 effector. Mol Biol Cell. 2017;28:1435-1443 pubmed publisher
Newman L, Schiavon C, Zhou C, Kahn R. The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors. PLoS ONE. 2017;12:e0175164 pubmed publisher
Kane M, Alban J, Desquiret Dumas V, Gueguen N, Ishak L, Ferre M, et al. Autophagy controls the pathogenicity of OPA1 mutations in dominant optic atrophy. J Cell Mol Med. 2017;21:2284-2297 pubmed publisher
Kirouac L, Rajic A, Cribbs D, Padmanabhan J. Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease. Eneuro. 2017;4: pubmed publisher
Dragoni S, Hudson N, Kenny B, Burgoyne T, McKenzie J, Gill Y, et al. Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions. J Immunol. 2017;198:4074-4085 pubmed publisher
Földi I, Anthoney N, Harrison N, Gangloff M, Verstak B, Nallasivan M, et al. Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila. J Cell Biol. 2017;216:1421-1438 pubmed publisher
Cain J, Kim D, Quast M, Shivega W, Patrick R, Moser C, et al. Nonsense pathogenic variants in exon 1 of PHOX2B lead to translational reinitiation in congenital central hypoventilation syndrome. Am J Med Genet A. 2017;173:1200-1207 pubmed publisher
Carrillo J, Calvete O, Pintado Berninches L, Manguan García C, Sevilla Navarro J, Arias Salgado E, et al. Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening. Hum Mol Genet. 2017;26:1900-1914 pubmed publisher
Gelmetti V, De Rosa P, Torosantucci L, Marini E, Romagnoli A, Di Rienzo M, et al. PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy. 2017;13:654-669 pubmed publisher
Jernström S, Hongisto V, Leivonen S, Due E, Tadele D, Edgren H, et al. Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response. Breast Cancer (Dove Med Press). 2017;9:185-198 pubmed publisher
Nederlof R, Weber N, Juffermans N, de Mol B, Hollmann M, Preckel B, et al. A randomized trial of remote ischemic preconditioning and control treatment for cardioprotection in sevoflurane-anesthetized CABG patients. BMC Anesthesiol. 2017;17:51 pubmed publisher
Nehybova T, Smarda J, Daniel L, Stiborek M, Kanicky V, Spasojevic I, et al. Wedelolactone Acts as Proteasome Inhibitor in Breast Cancer Cells. Int J Mol Sci. 2017;18: pubmed publisher
Lenis T, Sarfare S, Jiang Z, Lloyd M, Bok D, Radu R. Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease. Proc Natl Acad Sci U S A. 2017;114:3987-3992 pubmed publisher
Boutant M, Kulkarni S, Joffraud M, Ratajczak J, Valera Alberni M, Combe R, et al. Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J. 2017;36:1543-1558 pubmed publisher
Feldmann A, Bekbulat F, Huesmann H, Ulbrich S, Tatzelt J, Behl C, et al. The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochem Biophys Res Commun. 2017;486:738-743 pubmed publisher
Zhou D, Fu H, Zhang L, Zhang K, Min Y, Xiao L, et al. Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis. J Am Soc Nephrol. 2017;28:2322-2336 pubmed publisher
Le Grand M, Berges R, Pasquier E, Montero M, Borge L, Carrier A, et al. Akt targeting as a strategy to boost chemotherapy efficacy in non-small cell lung cancer through metabolism suppression. Sci Rep. 2017;7:45136 pubmed publisher
Li H, Zhou L, Dai J. Retinoic acid receptor-related orphan receptor RORα regulates differentiation and survival of keratinocytes during hypoxia. J Cell Physiol. 2018;233:641-650 pubmed publisher
Yoshikawa R, Takeuchi J, Yamada E, Nakano Y, Misawa N, Kimura Y, et al. Feline Immunodeficiency Virus Evolutionarily Acquires Two Proteins, Vif and Protease, Capable of Antagonizing Feline APOBEC3. J Virol. 2017;91: pubmed publisher
Syu J, Baba T, Huang J, Ogawa H, Hsieh C, Hu J, et al. Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth. Sci Rep. 2017;7:240 pubmed publisher
Marwaha R, Arya S, Jagga D, Kaur H, Tuli A, Sharma M. The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. J Cell Biol. 2017;216:1051-1070 pubmed publisher
Liang Z, Brown K, Carroll T, Taylor B, Vidal I, Hendrich B, et al. A high-resolution map of transcriptional repression. elife. 2017;6: pubmed publisher
Honda Y, Tsuchiya K, Sumiyoshi E, Haruta N, Sugimoto A. Tubulin isotype substitution revealed that isotype combination modulates microtubule dynamics in C. elegans embryos. J Cell Sci. 2017;130:1652-1661 pubmed publisher
van Haaften Visser D, Harakalová M, Mocholí E, van Montfrans J, Elkadri A, Rieter E, et al. Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease. J Biol Chem. 2017;292:7904-7920 pubmed publisher
Yamaji M, Jishage M, Meyer C, Suryawanshi H, Der E, Yamaji M, et al. DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs. Nature. 2017;543:568-572 pubmed publisher
Martinez Font E, Felipe Abrio I, Calabuig Fariñas S, Ramos R, Terrasa J, Vögler O, et al. Disruption of TCF/β-Catenin Binding Impairs Wnt Signaling and Induces Apoptosis in Soft Tissue Sarcoma Cells. Mol Cancer Ther. 2017;16:1166-1176 pubmed publisher
Gigant E, Stefanutti M, Laband K, Gluszek Kustusz A, Edwards F, Lacroix B, et al. Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes. Development. 2017;144:1674-1686 pubmed publisher
Iwahori S, Umaña A, VanDeusen H, Kalejta R. Human cytomegalovirus-encoded viral cyclin-dependent kinase (v-CDK) UL97 phosphorylates and inactivates the retinoblastoma protein-related p107 and p130 proteins. J Biol Chem. 2017;292:6583-6599 pubmed publisher
Chen D, Wu M, Li Y, Chang I, Yuan Q, Ekimyan Salvo M, et al. Targeting BMI1+ Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma. Cell Stem Cell. 2017;20:621-634.e6 pubmed publisher
Cruz Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, et al. PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation. Cell Stem Cell. 2017;20:689-705.e9 pubmed publisher
Dillon G, Tyler W, Omuro K, Kambouris J, Tyminski C, Henry S, et al. CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development. Neuron. 2017;93:1344-1358.e5 pubmed publisher
Mätlik K, Vihinen H, Bienemann A, Palgi J, Voutilainen M, Booms S, et al. Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra. Eneuro. 2017;4: pubmed publisher
Nagano T, Nakashima A, Onishi K, Kawai K, Awai Y, Kinugasa M, et al. Proline dehydrogenase promotes senescence through the generation of reactive oxygen species. J Cell Sci. 2017;130:1413-1420 pubmed publisher
Intlekofer A, Wang B, Liu H, Shah H, Carmona Fontaine C, Rustenburg A, et al. L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH. Nat Chem Biol. 2017;13:494-500 pubmed publisher
Teveroni E, Pellegrino M, Sacconi S, Calandra P, Cascino I, Farioli Vecchioli S, et al. Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity. J Clin Invest. 2017;127:1531-1545 pubmed publisher
Smith V, Cheng Y, Bryant B, Schorey J. Exosomes function in antigen presentation during an in vivo Mycobacterium tuberculosis infection. Sci Rep. 2017;7:43578 pubmed publisher
Xu H, Nie E, Deng G, Lai L, Sun F, Tian H, et al. Periostin is essential for periodontal ligament remodeling during orthodontic treatment. Mol Med Rep. 2017;15:1800-1806 pubmed publisher
Kabayama H, Tokushige N, Takeuchi M, Kabayama M, Fukuda M, Mikoshiba K. Parkin promotes proteasomal degradation of synaptotagmin IV by accelerating polyubiquitination. Mol Cell Neurosci. 2017;80:89-99 pubmed publisher
Chowański S, Lubawy J, Paluch Lubawa E, Spochacz M, Rosinski G, Słocińska M. The physiological role of fat body and muscle tissues in response to cold stress in the tropical cockroach Gromphadorhina coquereliana. PLoS ONE. 2017;12:e0173100 pubmed publisher
Lovelace M, Powter E, Coleman P, Zhao Y, Parker A, Chang G, et al. The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells. Mol Biol Cell. 2017;28:1066-1078 pubmed publisher
Love J, Bober B, Orozco E, White A, Bremner S, Lovering R, et al. mTOR regulates peripheral nerve response to tensile strain. J Neurophysiol. 2017;117:2075-2084 pubmed publisher
Frank S, Schulz V, Miranti C. A streamlined method for the design and cloning of shRNAs into an optimized Dox-inducible lentiviral vector. BMC Biotechnol. 2017;17:24 pubmed publisher
Barilari M, Bonfils G, Treins C, Koka V, De Villeneuve D, Fabrega S, et al. ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J. 2017;36:736-750 pubmed publisher
van Vliet A, Giordano F, Gerlo S, Segura I, Van Eygen S, Molenberghs G, et al. The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling. Mol Cell. 2017;65:885-899.e6 pubmed publisher
Raines S, Hodgkinson M, Dowle A, Pryor P. The Salmonella effector SseJ disrupts microtubule dynamics when ectopically expressed in normal rat kidney cells. PLoS ONE. 2017;12:e0172588 pubmed publisher
Suzuki T, Seki S, Hiramoto K, Naganuma E, Kobayashi E, Yamaoka A, et al. Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus. Nat Commun. 2017;8:14577 pubmed publisher
Cook E, Nelson J, Sorrentino V, Koenis D, Moeton M, Scheij S, et al. Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene. PLoS ONE. 2017;12:e0172721 pubmed publisher
Broz V, Kucerova L, Rouhova L, Fleischmannova J, Strnad H, Bryant P, et al. Drosophila imaginal disc growth factor 2 is a trophic factor involved in energy balance, detoxification, and innate immunity. Sci Rep. 2017;7:43273 pubmed publisher
Burk K, Mire E, Bellon A, Hocine M, Guillot J, Moraes F, et al. Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits. Nat Commun. 2017;8:14508 pubmed publisher
Rai R, Hu C, Broton C, Chen Y, Lei M, Chang S. NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres. Mol Cell. 2017;65:801-817.e4 pubmed publisher
Visochek L, Castiel A, Mittelman L, Elkin M, Atias D, Golan T, et al. Exclusive destruction of mitotic spindles in human cancer cells. Oncotarget. 2017;8:20813-20824 pubmed publisher
Makieva S, Dubicke A, Rinaldi S, Fransson E, Ekman Ordeberg G, Norman J. The preterm cervix reveals a transcriptomic signature in the presence of premature prelabor rupture of membranes. Am J Obstet Gynecol. 2017;216:602.e1-602.e21 pubmed publisher
Subramaniam M, Cicek M, Pitel K, Bruinsma E, Nelson Holte M, Withers S, et al. TIEG1 modulates ?-catenin sub-cellular localization and enhances Wnt signaling in bone. Nucleic Acids Res. 2017;45:5170-5182 pubmed publisher
Bas Orth C, Tan Y, Lau D, Bading H. Synaptic Activity Drives a Genomic Program That Promotes a Neuronal Warburg Effect. J Biol Chem. 2017;292:5183-5194 pubmed publisher
Weaver J, Arandjelovic S, Brown G, K Mendu S, S Schappe M, Buckley M, et al. Hematopoietic pannexin 1 function is critical for neuropathic pain. Sci Rep. 2017;7:42550 pubmed publisher
Yan X, Zhang H, Fan Q, Hu J, Tao R, Chen Q, et al. Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction. Circ Res. 2017;120:1116-1129 pubmed publisher
Liu Z, Yanagisawa K, Griesing S, Iwai M, Kano K, Hotta N, et al. TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas. Oncogene. 2017;36:3740-3748 pubmed publisher
DiMenna L, Yen W, Nicolás L, Sharma R, Saldanha Z, Chaudhuri J. Cutting Edge: The Transcription Factor Sox2 Regulates AID Expression in Class-Switched B Cells. J Immunol. 2017;198:2244-2248 pubmed publisher
Zhitomirsky B, Assaraf Y. Lysosomal accumulation of anticancer drugs triggers lysosomal exocytosis. Oncotarget. 2017;8:45117-45132 pubmed publisher
Toots M, Männik A, Mumm K, Tämm K, Tamm T, Ustav E, et al. Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay. PLoS Pathog. 2017;13:e1006168 pubmed publisher
Watters K, Inankur B, Gardiner J, Warrick J, Sherer N, Yin J, et al. Differential Disruption of Nucleocytoplasmic Trafficking Pathways by Rhinovirus 2A Proteases. J Virol. 2017;91: pubmed publisher
Zapotoczny G, Sekelsky J. Human Cell Assays for Synthesis-Dependent Strand Annealing and Crossing over During Double-Strand Break Repair. G3 (Bethesda). 2017;7:1191-1199 pubmed publisher
Segal J, Ward C. Novel peptides for deciphering structural and signalling functions of E-cadherin in mouse embryonic stem cells. Sci Rep. 2017;7:41827 pubmed publisher
Chen S, Lu W, Yueh M, Rettenmeier E, Liu M, Paszek M, et al. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. Proc Natl Acad Sci U S A. 2017;114:E1432-E1440 pubmed publisher
Bot C, Pfeiffer A, Giordano F, Manjeera D, Dantuma N, Ström L. Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage. J Cell Sci. 2017;130:1134-1146 pubmed publisher
Lu T, MacDonald J, Neukomm L, Sheehan A, Bradshaw R, Logan M, et al. Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling. Nat Commun. 2017;8:14355 pubmed publisher
Medina Contreras J, Colado Velázquez J, Gómez Viquez N, Mailloux Salinas P, Perez Torres I, Aranda Fraustro A, et al. Effects of topical capsaicin combined with moderate exercise on insulin resistance, body weight and oxidative stress in hypoestrogenic obese rats. Int J Obes (Lond). 2017;41:750-758 pubmed publisher
Perearnau A, Orlando S, Islam A, Gallastegui E, Martinez J, Jordan A, et al. p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes. Nucleic Acids Res. 2017;45:5086-5099 pubmed publisher
Tang L, Heller M, Meng Z, Yu L, Tang Y, Zhou M, et al. Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway. J Biol Chem. 2017;292:4302-4312 pubmed publisher
Zhou B, Zeng S, Li N, Yu L, Yang G, Yang Y, et al. Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury. Arterioscler Thromb Vasc Biol. 2017;37:675-684 pubmed publisher
Yue L, Li L, Li D, Yang Z, Han S, Chen M, et al. High-throughput screening for Survivin and Borealin interaction inhibitors in hepatocellular carcinoma. Biochem Biophys Res Commun. 2017;484:642-647 pubmed publisher
Shishido Y, Baba T, Sato T, Shima Y, Miyabayashi K, Inoue M, et al. Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells. Sci Rep. 2017;7:41912 pubmed publisher
Sorusch N, Baus K, Plutniok J, Samanta A, Knapp B, Nagel Wolfrum K, et al. Characterization of the ternary Usher syndrome SANS/ush2a/whirlin protein complex. Hum Mol Genet. 2017;26:1157-1172 pubmed publisher
Chiu Y, Jin X, Medina C, Leonhardt S, Kiessling V, Bennett B, et al. A quantized mechanism for activation of pannexin channels. Nat Commun. 2017;8:14324 pubmed publisher
Calderon T, Williams D, Lopez L, Eugenin E, Cheney L, Gaskill P, et al. Dopamine Increases CD14+CD16+ Monocyte Transmigration across the Blood Brain Barrier: Implications for Substance Abuse and HIV Neuropathogenesis. J Neuroimmune Pharmacol. 2017;12:353-370 pubmed publisher
Miyagi E, Kao S, Fumitaka M, Buckler White A, Plishka R, Strebel K. Long-term passage of Vif-null HIV-1 in CD4+ T cells expressing sub-lethal levels of APOBEC proteins fails to develop APOBEC resistance. Virology. 2017;504:1-11 pubmed publisher
Taniguchi K, Moroishi T, de Jong P, Krawczyk M, Grebbin B, Luo H, et al. YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis. Proc Natl Acad Sci U S A. 2017;114:1643-1648 pubmed publisher
Beydoun R, Hamood M, Gomez Zubieta D, Kondapalli K. Na+/H+ Exchanger 9 Regulates Iron Mobilization at the Blood-Brain Barrier in Response to Iron Starvation. J Biol Chem. 2017;292:4293-4301 pubmed publisher
Fang D, Gan H, Wang H, Zhou H, Zhang Z. Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells. Cell Cycle. 2017;16:1781-1789 pubmed publisher
Packer L, Geng X, Bonazzi V, Ju R, Mahon C, Cummings M, et al. PI3K Inhibitors Synergize with FGFR Inhibitors to Enhance Antitumor Responses in FGFR2mutant Endometrial Cancers. Mol Cancer Ther. 2017;16:637-648 pubmed publisher
Jahny E, Yang H, Liu B, Jahnke B, Lademann F, Knösel T, et al. The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation. PLoS ONE. 2017;12:e0170390 pubmed publisher
Lesch A, Rössler O, Thiel G. Extracellular Signal-Regulated Protein Kinase, c-Jun N-Terminal Protein Kinase, and Calcineurin Regulate Transient Receptor Potential M3 (TRPM3) Induced Activation of AP-1. J Cell Biochem. 2017;118:2409-2419 pubmed publisher
Phillips A, Millet A, Tigano M, Dubois S, Crimmins H, Babin L, et al. Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion. Mol Cell. 2017;65:527-538.e6 pubmed publisher
Graziano A, Cardile V, Avola R, Vicario N, Parenti C, Salvatorelli L, et al. Wilms' tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation. Oncotarget. 2017;8:13917-13931 pubmed publisher
Kim C, Tambe Y, Mukaisho K, Sugihara H, Kawauchi A, Inoue H. Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity. Oncol Lett. 2016;12:4850-4856 pubmed publisher
Shin S, Kim J, Lee J, Son Y, Lee M, Kim H, et al. Docosahexaenoic acid-mediated protein aggregates may reduce proteasome activity and delay myotube degradation during muscle atrophy in vitro. Exp Mol Med. 2017;49:e287 pubmed publisher
Sacoman J, Dagda R, Burnham Marusich A, Dagda R, Berninsone P. Mitochondrial O-GlcNAc Transferase (mOGT) Regulates Mitochondrial Structure, Function, and Survival in HeLa Cells. J Biol Chem. 2017;292:4499-4518 pubmed publisher
Neisch A, Neufeld T, Hays T. A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation. J Cell Biol. 2017;216:441-461 pubmed publisher
Horrigan S, Courville P, Sampey D, Zhou F, Cai S. Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations. elife. 2017;6: pubmed publisher
Chauvigné F, Parhi J, Ollé J, Cerdà J. Dual estrogenic regulation of the nuclear progestin receptor and spermatogonial renewal during gilthead seabream (Sparus aurata) spermatogenesis. Comp Biochem Physiol A Mol Integr Physiol. 2017;206:36-46 pubmed publisher
Sugioka K, Hamill D, Lowry J, McNeely M, Enrick M, Richter A, et al. Centriolar SAS-7 acts upstream of SPD-2 to regulate centriole assembly and pericentriolar material formation. elife. 2017;6: pubmed publisher
Saxon J, Sholl L, Janne P. EGFR L858M/L861Q cis Mutations Confer Selective Sensitivity to Afatinib. J Thorac Oncol. 2017;12:884-889 pubmed publisher
Phua S, Chiba S, Suzuki M, Su E, Roberson E, Pusapati G, et al. Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017;168:264-279.e15 pubmed publisher
Fiskin E, Bhogaraju S, Herhaus L, Kalayil S, Hahn M, Dikic I. Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA. Nat Commun. 2017;8:14004 pubmed publisher
Kalfon R, Koren L, Aviram S, Schwartz O, Hai T, Aronheim A. ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance. Cardiovasc Res. 2017;113:134-146 pubmed publisher
Olah J, Szénási T, Szunyogh S, Szabo A, Lehotzky A, Ovadi J. Further evidence for microtubule-independent dimerization of TPPP/p25. Sci Rep. 2017;7:40594 pubmed publisher
Velayos T, Martinez R, Alonso M, Garcia Etxebarria K, Aguayo A, Camarero C, et al. An Activating Mutation in STAT3 Results in Neonatal Diabetes Through Reduced Insulin Synthesis. Diabetes. 2017;66:1022-1029 pubmed publisher
Ji Z, Gao H, Jia L, Li B, Yu H. A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling. elife. 2017;6: pubmed publisher
Bae S, Shin M, Kim R, Shin D, Son T, Wee H, et al. Ninjurin1 Assembles Into a Homomeric Protein Complex Maintained by N-linked Glycosylation. J Cell Biochem. 2017;118:2219-2230 pubmed publisher
Brasacchio D, Alsop A, Noori T, Lufti M, Iyer S, Simpson K, et al. Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization. Cell Death Differ. 2017;24:961-970 pubmed publisher
Pan D, Klare K, Petrovic A, Take A, Walstein K, Singh P, et al. CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading. elife. 2017;6: pubmed publisher
Kinosada H, Yasunaga J, Shimura K, Miyazato P, Onishi C, Iyoda T, et al. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors. PLoS Pathog. 2017;13:e1006120 pubmed publisher
Newman L, Schiavon C, Kahn R. Plasmids for variable expression of proteins targeted to the mitochondrial matrix or intermembrane space. Cell Logist. 2016;6:e1247939 pubmed publisher
Tsuchida K, Tsujita T, Hayashi M, Ojima A, Keleku Lukwete N, Katsuoka F, et al. Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation. Free Radic Biol Med. 2017;103:236-247 pubmed publisher
Villanueva A, Falcón P, Espinoza N, R L, Milla L, Hernández SanMiguel E, et al. The Netrin-4/ Neogenin-1 axis promotes neuroblastoma cell survival and migration. Oncotarget. 2017;8:9767-9782 pubmed publisher
Takada M, Zhuang M, Inuzuka H, Zhang J, Zurlo G, Zhang J, et al. EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor. Oncotarget. 2017;8:6787-6795 pubmed publisher
Kim M, Ahn H, Lee E, Kim S, Kim Y, Park J, et al. Hepatic inflammatory cytokine production can be regulated by modulating sphingomyelinase and ceramide synthase 6. Int J Mol Med. 2017;39:453-462 pubmed publisher
Batzenschlager M, Schmit A, Herzog E, Fuchs J, Schubert V, Houlné G, et al. MGO3 and GIP1 act synergistically for the maintenance of centromeric cohesion. Nucleus. 2017;8:98-105 pubmed publisher
Li X, Morita M, Kikuguchi C, Takahashi A, Suzuki T, Yamamoto T. Adipocyte-specific disruption of mouse Cnot3 causes lipodystrophy. FEBS Lett. 2017;591:358-368 pubmed publisher
Toombs J, Sytnikova Y, Chirn G, Ang I, Lau N, Blower M. Xenopus Piwi proteins interact with a broad proportion of the oocyte transcriptome. RNA. 2017;23:504-520 pubmed publisher
Altieri B, Sbiera S, Della Casa S, Weigand I, Wild V, Steinhauer S, et al. Livin/BIRC7 expression as malignancy marker in adrenocortical tumors. Oncotarget. 2017;8:9323-9338 pubmed publisher
Wu Q, Lian T, Fan X, Song C, Gaur U, Mao X, et al. 2,5-Dimethyl-Celecoxib Extends Drosophila Life Span via a Mechanism That Requires Insulin and Target of Rapamycin Signaling. J Gerontol A Biol Sci Med Sci. 2017;72:1334-1341 pubmed publisher
Murko C, Bronner M. Tissue specific regulation of the chick Sox10E1 enhancer by different Sox family members. Dev Biol. 2017;422:47-57 pubmed publisher
Oralová V, Matalova E, Killinger M, Knopfova L, Smarda J, Buchtová M. Osteogenic Potential of the Transcription Factor c-MYB. Calcif Tissue Int. 2017;100:311-322 pubmed publisher
Vaidyanathan B, Chaudhry A, Yewdell W, Angeletti D, Yen W, Wheatley A, et al. The aryl hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med. 2017;214:197-208 pubmed publisher
Aeby E, Ahmed W, Redon S, Simanis V, Lingner J. Peroxiredoxin 1 Protects Telomeres from Oxidative Damage and Preserves Telomeric DNA for Extension by Telomerase. Cell Rep. 2016;17:3107-3114 pubmed publisher
Sun T, Yang L, Kaur H, Pestel J, Looso M, Nolte H, et al. A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib. J Cell Biol. 2017;216:199-215 pubmed publisher
Pike T, Brownlow N, Kjaer S, Carlton J, Parker P. PKC? switches Aurora B specificity to exit the abscission checkpoint. Nat Commun. 2016;7:13853 pubmed publisher
Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, et al. The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation. Sci Rep. 2016;6:22 pubmed publisher
Tromer E, Bade D, Snel B, Kops G. Phylogenomics-guided discovery of a novel conserved cassette of short linear motifs in BubR1 essential for the spindle checkpoint. Open Biol. 2016;6: pubmed publisher
Kolyvas E, Rudloff M, Poruchynsky M, Landsman R, Hollevoet K, Venzon D, et al. Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes. Oncotarget. 2017;8:9189-9199 pubmed publisher
Lee Y, Kim K, Yoon H, Lee O, Kim E, Park M, et al. RASD1 Knockdown Results in Failure of Oocyte Maturation. Cell Physiol Biochem. 2016;40:1289-1302 pubmed publisher
Caino M, Seo J, Aguinaldo A, Wait E, Bryant K, Kossenkov A, et al. A neuronal network of mitochondrial dynamics regulates metastasis. Nat Commun. 2016;7:13730 pubmed publisher
Morley S, Qi Y, Iovino L, Andolfi L, Guo D, Kalebic N, et al. Acetylated tubulin is essential for touch sensation in mice. elife. 2016;5: pubmed publisher
Liu L, Guan H, Li Y, Ying Z, Wu J, Zhu X, et al. Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness. Mol Cell Biol. 2017;37: pubmed publisher
Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, et al. Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines. J Cancer Res Clin Oncol. 2017;143:573-600 pubmed publisher
Sokolova M, Turunen M, Mortusewicz O, Kivioja T, Herr P, Vähärautio A, et al. Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion. Cell Cycle. 2017;16:189-199 pubmed publisher
Pavel M, Imarisio S, Menzies F, Jimenez Sanchez M, Siddiqi F, Wu X, et al. CCT complex restricts neuropathogenic protein aggregation via autophagy. Nat Commun. 2016;7:13821 pubmed publisher
Kawatani M, Muroi M, Wada A, Inoue G, Futamura Y, Aono H, et al. Proteomic profiling reveals that collismycin A is an iron chelator. Sci Rep. 2016;6:38385 pubmed publisher
Farabaugh K, Majumder M, Guan B, Jobava R, Wu J, Krokowski D, et al. Protein Kinase R Mediates the Inflammatory Response Induced by Hyperosmotic Stress. Mol Cell Biol. 2017;37: pubmed publisher
Baird L, Tsujita T, Kobayashi E, Funayama R, Nagashima T, Nakayama K, et al. A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways. Mol Cell Biol. 2017;37: pubmed publisher
Lin T, Neuner A, Flemming D, Liu P, Chinen T, Jäkle U, et al. MOZART1 and ?-tubulin complex receptors are both required to turn ?-TuSC into an active microtubule nucleation template. J Cell Biol. 2016;215:823-840 pubmed
Greggio C, Jha P, Kulkarni S, Lagarrigue S, Broskey N, Boutant M, et al. Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle. Cell Metab. 2017;25:301-311 pubmed publisher
Li Y, Li X, Kan Q, Zhang M, Li X, Xu R, et al. Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas. Oncotarget. 2017;8:1058-1073 pubmed publisher
Kvainickas A, Orgaz A, Nägele H, Diedrich B, Heesom K, Dengjel J, et al. Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50. J Cell Sci. 2017;130:382-395 pubmed publisher
Wan L, Maisonneuve P, Szilard R, Lambert J, Ng T, Manczyk N, et al. Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7. Nucleic Acids Res. 2017;45:805-817 pubmed publisher
Chen Y, Zhang J, Li D, Jiang J, Wang Y, Si S. Identification of a novel Polo-like kinase 1 inhibitor that specifically blocks the functions of Polo-Box domain. Oncotarget. 2017;8:1234-1246 pubmed publisher
McKenzie C, D Avino P. Investigating cytokinesis failure as a strategy in cancer therapy. Oncotarget. 2016;7:87323-87341 pubmed publisher
Goreczny G, Ouderkirk Pecone J, Olson E, Krendel M, Turner C. Hic-5 remodeling of the stromal matrix promotes breast tumor progression. Oncogene. 2017;36:2693-2703 pubmed publisher
Sharbeen G, McCarroll J, Liu J, Youkhana J, Limbri L, Biankin A, et al. Delineating the Role of ?IV-Tubulins in Pancreatic Cancer: ?IVb-Tubulin Inhibition Sensitizes Pancreatic Cancer Cells to Vinca Alkaloids. Neoplasia. 2016;18:753-764 pubmed publisher
Shosha E, Xu Z, Yokota H, Saul A, Rojas M, Caldwell R, et al. Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury. Cell Death Dis. 2016;7:e2483 pubmed publisher
Villarroya Beltri C, Baixauli F, Mittelbrunn M, Fernandez Delgado I, Torralba D, Moreno Gonzalo O, et al. ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins. Nat Commun. 2016;7:13588 pubmed publisher
Kuchmiy A, D Hont J, Hochepied T, Lamkanfi M. NLRP2 controls age-associated maternal fertility. J Exp Med. 2016;213:2851-2860 pubmed
Baird M, Billington N, Wang A, Adelstein R, Sellers J, Fischer R, et al. Local pulsatile contractions are an intrinsic property of the myosin 2A motor in the cortical cytoskeleton of adherent cells. Mol Biol Cell. 2017;28:240-251 pubmed publisher
Morishita M, Kawamoto T, Hara H, Onishi Y, Ueha T, Minoda M, et al. AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway. Int J Oncol. 2017;50:23-30 pubmed publisher
Tirmarche S, Kimura S, Dubruille R, Horard B, Loppin B. Unlocking sperm chromatin at fertilization requires a dedicated egg thioredoxin in Drosophila. Nat Commun. 2016;7:13539 pubmed publisher
Ikink G, Boer M, Bakker E, Hilkens J. IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation. Nat Commun. 2016;7:13567 pubmed publisher
Berth S, Mesnard Hoaglin N, Wang B, Kim H, Song Y, Sapar M, et al. HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways. ASN Neuro. 2016;8: pubmed
Son M, Kawasaki I, Oh B, Shim Y. LIN-23, an E3 Ubiquitin Ligase Component, Is Required for the Repression of CDC-25.2 Activity during Intestinal Development in Caenorhabditis elegans. Mol Cells. 2016;39:834-840 pubmed
Yang Y, Jiang Z, Bolnick A, Dai J, Puscheck E, Rappolee D. Departure from optimal O2 level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation. J Reprod Dev. 2017;63:87-94 pubmed publisher
Sengupta S, Rath U, Yao C, Zavortink M, Wang C, Girton J, et al. Digitor/dASCIZ Has Multiple Roles in Drosophila Development. PLoS ONE. 2016;11:e0166829 pubmed publisher
Sulaiman A, Sulaiman B, Khouri L, McGarry S, Nessim C, Arnaout A, et al. Both bulk and cancer stem cell subpopulations in triple-negative breast cancer are susceptible to Wnt, HDAC, and ER? coinhibition. FEBS Lett. 2016;590:4606-4616 pubmed publisher
Ernst C, Pike J, Aitken S, Long H, Eling N, Stojic L, et al. Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis. elife. 2016;5: pubmed publisher
Quesada López T, Cereijo R, Turatsinze J, Planavila A, Cairó M, Gavaldà Navarro A, et al. The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes. Nat Commun. 2016;7:13479 pubmed publisher
Mann B, Balchand S, Wadsworth P. Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics. Mol Biol Cell. 2017;28:65-75 pubmed publisher
Alvarez Curto E, Inoue A, Jenkins L, Raihan S, Prihandoko R, Tobin A, et al. Targeted Elimination of G Proteins and Arrestins Defines Their Specific Contributions to Both Intensity and Duration of G Protein-coupled Receptor Signaling. J Biol Chem. 2016;291:27147-27159 pubmed publisher
Bono S, Lulli M, D Agostino V, Di Gesualdo F, Loffredo R, Cipolleschi M, et al. Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction. Oncotarget. 2016;7:84810-84825 pubmed publisher
Poburski D, Leovsky C, Boerner J, Szimmtenings L, Ristow M, Glei M, et al. Insulin-IGF signaling affects cell transformation in the BALB/c 3T3 cell model. Sci Rep. 2016;6:37120 pubmed publisher
Ohashi A, Ohori M, Iwai K. Motor activity of centromere-associated protein-E contributes to its localization at the center of the midbody to regulate cytokinetic abscission. Oncotarget. 2016;7:79964-79980 pubmed publisher
Zha J, Liu X, Zhu J, Liu S, Lu S, Xu P, et al. A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses. Sci Rep. 2016;6:36631 pubmed publisher
Isono T, Chano T, Yoshida T, Kageyama S, Kawauchi A, Suzaki M, et al. Hydroxyl-HIF2-alpha is potential therapeutic target for renal cell carcinomas. Am J Cancer Res. 2016;6:2263-2276 pubmed
Lin M, Lee S. Stathmin-like 4 is critical for the maintenance of neural progenitor cells in dorsal midbrain of zebrafish larvae. Sci Rep. 2016;6:36188 pubmed publisher
Mazo G, Soplop N, Wang W, Uryu K, Tsou M. Spatial Control of Primary Ciliogenesis by Subdistal Appendages Alters Sensation-Associated Properties of Cilia. Dev Cell. 2016;39:424-437 pubmed publisher
Kimura S, Loppin B. The Drosophila chromosomal protein Mst77F is processed to generate an essential component of mature sperm chromatin. Open Biol. 2016;6: pubmed
Balachandran R, Heighington C, Starostina N, Anderson J, Owen D, Vasudevan S, et al. The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage. J Cell Biol. 2016;215:151-166 pubmed
Shimizu T, Osanai Y, Tanaka K, Abe M, Natsume R, Sakimura K, et al. YAP functions as a mechanotransducer in oligodendrocyte morphogenesis and maturation. Glia. 2017;65:360-374 pubmed publisher
Tan R, Chartoumpekis D, Rush B, Zhou D, Fu H, Kensler T, et al. Keap1 hypomorphism protects against ischemic and obstructive kidney disease. Sci Rep. 2016;6:36185 pubmed publisher
Moriwaki T, Goshima G. Five factors can reconstitute all three phases of microtubule polymerization dynamics. J Cell Biol. 2016;215:357-368 pubmed
Granados Jaén A, Angulo Ibáñez M, Rovira Clavé X, Gamez C, Soriano F, Reina M, et al. Absence of ERK5/MAPK7 delays tumorigenesis in Atm-/- mice. Oncotarget. 2016;7:74435-74447 pubmed publisher
Beyer S, Pontis J, Schirwis E, Battisti V, Rudolf A, Le Grand F, et al. Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation. Cell Discov. 2016;2:16037 pubmed
Kedage V, Selvaraj N, Nicholas T, Budka J, Plotnik J, Jerde T, et al. An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. Cell Rep. 2016;17:1289-1301 pubmed publisher
Brinkmann C, Schulte Körne B, Grau M, Obels S, Kemmerling R, Schiffer T, et al. Effects of Endurance Training on the Skeletal Muscle Nitric Oxide Metabolism in Insulin-Independent Type 2 Diabetic Men-A Pilot Study. Metab Syndr Relat Disord. 2017;15:52-58 pubmed publisher
Kass E, Lim P, Helgadottir H, Moynahan M, Jasin M. Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation. Nat Commun. 2016;7:13241 pubmed publisher
Hinckelmann M, Virlogeux A, Niehage C, Poujol C, Choquet D, Hoflack B, et al. Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport. Nat Commun. 2016;7:13233 pubmed publisher
Terwisscha van Scheltinga A, Ogasawara A, Pacheco G, Vanderbilt A, Tinianow J, Gupta N, et al. Preclinical Efficacy of an Antibody-Drug Conjugate Targeting Mesothelin Correlates with Quantitative 89Zr-ImmunoPET. Mol Cancer Ther. 2017;16:134-142 pubmed publisher
Shi Y, Zhou W, Cheng L, Chen C, Huang Z, Fang X, et al. Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells. Cell Death Differ. 2017;24:167-180 pubmed publisher
Lorenz V, Ditamo Y, Cejas R, Carrizo M, Bennett E, Clausen H, et al. Extrinsic Functions of Lectin Domains in O-N-Acetylgalactosamine Glycan Biosynthesis. J Biol Chem. 2016;291:25339-25350 pubmed
Sureda Gómez M, Martín Durán J, Adell T. Localization of planarian ?-CATENIN-1 reveals multiple roles during anterior-posterior regeneration and organogenesis. Development. 2016;143:4149-4160 pubmed
Sellou H, Lebeaupin T, Chapuis C, Smith R, Hegele A, Singh H, et al. The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage. Mol Biol Cell. 2016;27:3791-3799 pubmed
Ratajczak J, Joffraud M, Trammell S, Ras R, Canela N, Boutant M, et al. NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells. Nat Commun. 2016;7:13103 pubmed publisher
Rue L, Bañez Coronel M, Creus Muncunill J, Giralt A, Alcalá Vida R, Mentxaka G, et al. Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels. J Clin Invest. 2016;126:4319-4330 pubmed publisher
Shenoy A, Jin Y, Luo H, Tang M, Pampo C, Shao R, et al. Epithelial-to-mesenchymal transition confers pericyte properties on cancer cells. J Clin Invest. 2016;126:4174-4186 pubmed publisher
Liao Y, Lee T, Twu Y, Hsu S, Yang C, Wang C, et al. Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver. J Biomed Sci. 2016;23:69 pubmed
Sassmann Schweda A, Singh P, Tang C, Wietelmann A, Wettschureck N, Offermanns S. Increased apoptosis and browning of TAK1-deficient adipocytes protects against obesity. JCI Insight. 2016;1:e81175 pubmed publisher
Redli P, Gasic I, Meraldi P, Nigg E, Santamaria A. The Ska complex promotes Aurora B activity to ensure chromosome biorientation. J Cell Biol. 2016;215:77-93 pubmed
Rossi V, Lispi M, Longobardi S, Mattei M, Di Rella F, Salustri A, et al. LH prevents cisplatin-induced apoptosis in oocytes and preserves female fertility in mouse. Cell Death Differ. 2017;24:72-82 pubmed publisher
Yang Y, Arenas Hernandez M, Gomez Lopez N, Dai J, Parker G, Puscheck E, et al. Hypoxic Stress Forces Irreversible Differentiation of a Majority of Mouse Trophoblast Stem Cells Despite FGF4. Biol Reprod. 2016;95:110 pubmed
Chandrasekharan J, Huang X, Hwang A, Sharma Walia N. Altering the Anti-inflammatory Lipoxin Microenvironment: a New Insight into Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis. J Virol. 2016;90:11020-11031 pubmed
Servadio M, Melancia F, Manduca A, Di Masi A, Schiavi S, Cartocci V, et al. Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid. Transl Psychiatry. 2016;6:e902 pubmed publisher
Yamada E, Yoshikawa R, Nakano Y, Misawa N, Kobayashi T, Ren F, et al. A naturally occurring bovine APOBEC3 confers resistance to bovine lentiviruses: implication for the co-evolution of bovids and their lentiviruses. Sci Rep. 2016;6:33988 pubmed publisher
Blockhuys S, Liu N, Agarwal N, Enejder A, Loitto V, Sun X. X-radiation enhances the collagen type I strap formation and migration potentials of colon cancer cells. Oncotarget. 2016;7:71390-71399 pubmed publisher
Sikora M, Jacobsen B, Levine K, Chen J, Davidson N, Lee A, et al. WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines. Breast Cancer Res. 2016;18:92 pubmed publisher
Conte A, Kisslinger A, Procaccini C, Paladino S, Oliviero O, De Amicis F, et al. Convergent Effects of Resveratrol and PYK2 on Prostate Cells. Int J Mol Sci. 2016;17: pubmed publisher
Egholm C, Khammy M, Dalsgaard T, Mazur A, Tritsaris K, Hansen A, et al. GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries. Am J Physiol Heart Circ Physiol. 2016;311:H1214-H1224 pubmed publisher
Hernandez Tiedra S, Fabrias G, Davila D, Salanueva I, Casas J, Montes L, et al. Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. Autophagy. 2016;12:2213-2229 pubmed
Matsukawa K, Hashimoto T, Matsumoto T, Ihara R, Chihara T, Miura M, et al. Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43. J Biol Chem. 2016;291:23464-23476 pubmed
Neumann Y, Bruns S, Rohde M, Prajsnar T, Foster S, Schmitz I. Intracellular Staphylococcus aureus eludes selective autophagy by activating a host cell kinase. Autophagy. 2016;12:2069-2084 pubmed
Hoppstädter J, Hachenthal N, Valbuena Perez J, Lampe S, Astanina K, Kunze M, et al. Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages. J Biol Chem. 2016;291:22949-22960 pubmed
Zhou D, Tian Y, Sun L, Zhou L, Xiao L, Tan R, et al. Matrix Metalloproteinase-7 Is a Urinary Biomarker and Pathogenic Mediator of Kidney Fibrosis. J Am Soc Nephrol. 2017;28:598-611 pubmed publisher
Lacroix M, Rodier G, Kirsh O, Houles T, Delpech H, Seyran B, et al. E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity. Proc Natl Acad Sci U S A. 2016;113:10998-1003 pubmed publisher
García Heredia J, Verdugo Sivianes E, Lucena Cacace A, Molina Pinelo S, Carnero A. Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy. Oncotarget. 2016;7:63611-63628 pubmed publisher
Fu H, Tian Y, Zhou L, Zhou D, Tan R, Stolz D, et al. Tenascin-C Is a Major Component of the Fibrogenic Niche in Kidney Fibrosis. J Am Soc Nephrol. 2017;28:785-801 pubmed publisher
Poburski D, Thierbach R. Improvement of the BALB/c-3T3 cell transformation assay: a tool for investigating cancer mechanisms and therapies. Sci Rep. 2016;6:32966 pubmed publisher
Banks C, Boanca G, Lee Z, Eubanks C, Hattem G, Peak A, et al. TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions. Mol Cell Proteomics. 2016;15:3435-3449 pubmed
Zhou L, Ma S, Yeung P, Wong Y, Tsim K, So K, et al. Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac. Transl Psychiatry. 2016;6:e881 pubmed publisher
Lee Z, Prouteau M, Gotta M, Barral Y. Compartmentalization of the endoplasmic reticulum in the early C. elegans embryos. J Cell Biol. 2016;214:665-76 pubmed publisher
Chen Y, Kuo H, Bornschein U, Takahashi H, Chen S, Lu K, et al. Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c. Nat Neurosci. 2016;19:1513-1522 pubmed publisher
Boehme J, Sun X, Tormos K, Gong W, Kellner M, Datar S, et al. Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation. Am J Physiol Heart Circ Physiol. 2016;311:H944-H957 pubmed publisher
Kofent J, Zhang J, Spagnoli F. The histone methyltransferase Setd7 promotes pancreatic progenitor identity. Development. 2016;143:3573-3581 pubmed
Joly N, Martino L, Gigant E, Dumont J, Pintard L. Microtubule-severing activity of the AAA+ ATPase Katanin is essential for female meiotic spindle assembly. Development. 2016;143:3604-3614 pubmed
Péladeau C, Heibein A, Maltez M, Copeland S, Copeland J. A specific FMNL2 isoform is up-regulated in invasive cells. BMC Cell Biol. 2016;17:32 pubmed publisher
Sanchez Alonso J, Bhargava A, O HARA T, Glukhov A, Schobesberger S, Bhogal N, et al. Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure. Circ Res. 2016;119:944-55 pubmed publisher
Zhang T, Kwiatkowski N, Olson C, Dixon Clarke S, Abraham B, Greifenberg A, et al. Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nat Chem Biol. 2016;12:876-84 pubmed publisher
Scott D, Rhee D, Duda D, Kelsall I, Olszewski J, Paulo J, et al. Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation. Cell. 2016;166:1198-1214.e24 pubmed publisher
de Almeida Pereira L, Magalhães C, Repossi M, Thorstenberg M, Sholl Franco A, Coutinho Silva R, et al. Adenine Nucleotides Control Proliferation In Vivo of Rat Retinal Progenitors by P2Y1 Receptor. Mol Neurobiol. 2017;54:5142-5155 pubmed publisher
Duan H, Wang C, Wang M, Gao X, Yan M, Akram S, et al. Phosphorylation of PP1 Regulator Sds22 by PLK1 Ensures Accurate Chromosome Segregation. J Biol Chem. 2016;291:21123-21136 pubmed
Stork C, Bocek M, Crossley M, Sollier J, Sanz L, Chedin F, et al. Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage. elife. 2016;5: pubmed publisher
Jungas T, Perchey R, Fawal M, Callot C, Froment C, Burlet Schiltz O, et al. Eph-mediated tyrosine phosphorylation of citron kinase controls abscission. J Cell Biol. 2016;214:555-69 pubmed publisher
Soeda S, Yamada Nomoto K, Ohsugi M. The microtubule-binding and coiled-coil domains of Kid are required to turn off the polar ejection force at anaphase. J Cell Sci. 2016;129:3609-3619 pubmed
Colin E, Daniel J, Ziegler A, Wakim J, Scrivo A, Haack T, et al. Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy. Am J Hum Genet. 2016;99:695-703 pubmed publisher
Nagano T, Nakano M, Nakashima A, Onishi K, Yamao S, Enari M, et al. Identification of cellular senescence-specific genes by comparative transcriptomics. Sci Rep. 2016;6:31758 pubmed publisher
Ohmer M, Weber A, Sutter G, Ehrhardt K, Zimmermann A, Häcker G. Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis. Cell Death Dis. 2016;7:e2340 pubmed publisher
Sheehan P, Zhu M, Beskow A, Vollmer C, Waites C. Activity-Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway. J Neurosci. 2016;36:8668-86 pubmed publisher
Gómez Puerto M, Verhagen L, Braat A, Lam E, Coffer P, Lorenowicz M. Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation. Autophagy. 2016;12:1804-1816 pubmed
Berger P, Winn M, Miranti C. Miz1, a Novel Target of ING4, Can Drive Prostate Luminal Epithelial Cell Differentiation. Prostate. 2017;77:49-59 pubmed publisher
Lee S, Caviness K, Albright E, Lee J, Gelbmann C, Rak M, et al. Long and Short Isoforms of the Human Cytomegalovirus UL138 Protein Silence IE Transcription and Promote Latency. J Virol. 2016;90:9483-94 pubmed publisher
Alba Castellón L, Olivera Salguero R, Mestre Farrera A, Peña R, Herrera M, Bonilla F, et al. Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis. Cancer Res. 2016;76:6205-6217 pubmed
Amatori S, Mazzoni L, Alvarez Suarez J, Giampieri F, Gasparrini M, Forbes Hernández T, et al. Polyphenol-rich strawberry extract (PRSE) shows in vitro and in vivo biological activity against invasive breast cancer cells. Sci Rep. 2016;6:30917 pubmed publisher
Zhang H, Alshareef A, Wu C, Jiao J, Sorensen P, Lai R, et al. miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma. Carcinogenesis. 2016;37:858-869 pubmed publisher
Wang Y, Dehigaspitiya D, Levine P, Profit A, Haugbro M, Imberg Kazdan K, et al. Multivalent Peptoid Conjugates Which Overcome Enzalutamide Resistance in Prostate Cancer Cells. Cancer Res. 2016;76:5124-32 pubmed publisher
Chanduri M, Rai A, Malla A, Wu M, Fiedler D, Mallik R, et al. Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport. Biochem J. 2016;473:3031-47 pubmed publisher
Tsai S, Chang Y, Swamy K, Chiang R, Huang D. GAGA factor, a positive regulator of global gene expression, modulates transcriptional pausing and organization of upstream nucleosomes. Epigenetics Chromatin. 2016;9:32 pubmed publisher
Liefke R, Shi Y. The PRC2-associated factor C17orf96 is a novel CpG island regulator in mouse ES cells. Cell Discov. 2015;1:15008 pubmed publisher
Bernabé Rubio M, Andrés G, Casares Arias J, Fernández Barrera J, Rangel L, Reglero Real N, et al. Novel role for the midbody in primary ciliogenesis by polarized epithelial cells. J Cell Biol. 2016;214:259-73 pubmed publisher
Cai Z, Zhang A, Choksi S, Li W, Li T, Zhang X, et al. Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration. Cell Res. 2016;26:886-900 pubmed publisher
Rong Z, Ouyang Z, Magin R, Marmorstein R, Yu H. Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion. J Biol Chem. 2016;291:19079-91 pubmed publisher
Kammoun M, Meme S, Meme W, Subramaniam M, Hawse J, Canon F, et al. Impact of TIEG1 on the structural properties of fast- and slow-twitch skeletal muscle. Muscle Nerve. 2017;55:410-416 pubmed publisher
Sommer A, Hermawan A, Mickler F, Ljepoja B, Knyazev P, Bräuchle C, et al. Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases. Oncotarget. 2016;7:50461-50476 pubmed publisher
Lo Furno D, Graziano A, Avola R, Giuffrida R, Perciavalle V, Bonina F, et al. A Citrus bergamia Extract Decreases Adipogenesis and Increases Lipolysis by Modulating PPAR Levels in Mesenchymal Stem Cells from Human Adipose Tissue. PPAR Res. 2016;2016:4563815 pubmed publisher
Stein R, Kapplusch F, Heymann M, Russ S, Staroske W, Hedrich C, et al. Enzymatically Inactive Procaspase 1 stabilizes the ASC Pyroptosome and Supports Pyroptosome Spreading during Cell Division. J Biol Chem. 2016;291:18419-29 pubmed publisher
Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork Geleta A, Blecha J, Endaya B, et al. Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer. Antioxid Redox Signal. 2017;26:84-103 pubmed publisher
Czulkies B, Mastroianni J, Lutz L, Lang S, Schwan C, Schmidt G, et al. Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells. Oncotarget. 2017;8:37009-37022 pubmed publisher
Fernández B, Fdez E, Gomez Suaga P, Gil F, Molina Villalba I, Ferrer I, et al. Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A. Autophagy. 2016;12:1487-506 pubmed publisher
Yin C, He D, Chen S, Tan X, Sang N. Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate. Oncotarget. 2016;7:47494-47510 pubmed publisher
Calise S, Purich D, Nguyen T, Saleem D, Krueger C, Yin J, et al. 'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway. J Cell Sci. 2016;129:3042-52 pubmed publisher
Cairo M, Villarroya J, Cereijo R, Campderros L, Giralt M, Villarroya F. Thermogenic activation represses autophagy in brown adipose tissue. Int J Obes (Lond). 2016;40:1591-1599 pubmed publisher
Murphy M, Chatterjee S, Jain S, KATARI M, DasGupta R. TCF7L1 Modulates Colorectal Cancer Growth by Inhibiting Expression of the Tumor-Suppressor Gene EPHB3. Sci Rep. 2016;6:28299 pubmed publisher
Drummond C, Esfandiari A, Liu J, Lu X, Hutton C, Jackson J, et al. TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation. Oncotarget. 2016;7:46203-46218 pubmed publisher
Zhao J, Shyue S, Kou Y, Lu T, Lee T. Transient Receptor Potential Ankyrin 1 Channel Involved in Atherosclerosis and Macrophage-Foam Cell Formation. Int J Biol Sci. 2016;12:812-23 pubmed publisher
Gaume X, Place C, Delage H, Mongelard F, Monier K, Bouvet P. Expression of Nucleolin Affects Microtubule Dynamics. PLoS ONE. 2016;11:e0157534 pubmed publisher
Park S, Piao Y, Jeong K, Dong J, de Groot J. Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models. Mol Cancer Ther. 2016;15:2187-97 pubmed publisher
Ma W, Schubert V, Martis M, Hause G, Liu Z, Shen Y, et al. The distribution of ?-kleisin during meiosis in the holocentromeric plant Luzula elegans. Chromosome Res. 2016;24:393-405 pubmed publisher
Cheng M, Liu L, Lao Y, Liao W, Liao M, Luo X, et al. MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Oncotarget. 2016;7:42274-42287 pubmed publisher
Feng R, Yan Z, Li B, Yu M, Sang Q, Tian G, et al. Mutations in TUBB8 cause a multiplicity of phenotypes in human oocytes and early embryos. J Med Genet. 2016;53:662-71 pubmed publisher
Munoz D, Cassiani P, Li L, Billy E, Korn J, Jones M, et al. CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions. Cancer Discov. 2016;6:900-13 pubmed publisher
Lee S, Rigas N, Lee C, Bang A, Srikanth S, Gwack Y, et al. Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma. Oncotarget. 2016;7:43239-43255 pubmed publisher
Safina D, Schlitt F, Romeo R, Pflanzner T, Pietrzik C, Narayanaswami V, et al. Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation. Glia. 2016;64:1363-80 pubmed publisher
Much C, Auchynnikava T, Pavlinić D, Buness A, Rappsilber J, Benes V, et al. Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein. PLoS Genet. 2016;12:e1006095 pubmed publisher
Maday S, Holzbaur E. Compartment-Specific Regulation of Autophagy in Primary Neurons. J Neurosci. 2016;36:5933-45 pubmed publisher
Wike C, Graves H, Wason A, Hawkins R, Gopalakrishnan J, SCHUMACHER J, et al. Excess free histone H3 localizes to centrosomes for proteasome-mediated degradation during mitosis in metazoans. Cell Cycle. 2016;15:2216-2225 pubmed
Kasugai Y, Yoshida N, Ohshima K, Matsuo K, Seto M, Tsuzuki S. New mouse model of acute adult T-cell leukemia generated by transplantation of AKT, BCLxL, and HBZ-transduced T cells. Cancer Sci. 2016;107:1072-8 pubmed publisher
Rennoll S, Eshelman M, Raup Konsavage W, Kawasawa Y, Yochum G. The MYC 3' Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells. Cancers (Basel). 2016;8: pubmed publisher
Jacobsen A, Heijmans N, Verkaar F, Smit M, Heringa J, van Amerongen R, et al. Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling. PLoS ONE. 2016;11:e0155743 pubmed publisher
Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, et al. Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival. Sci Rep. 2016;6:26521 pubmed publisher
Klein S, Dieterich L, Mathelier A, Chong C, Sliwa Primorac A, Hong Y, et al. DeepCAGE transcriptomics identify HOXD10 as a transcription factor regulating lymphatic endothelial responses to VEGF-C. J Cell Sci. 2016;129:2573-85 pubmed publisher
Jhuraney A, Woods N, Wright G, Rix L, Kinose F, Kroeger J, et al. PAXIP1 Potentiates the Combination of WEE1 Inhibitor AZD1775 and Platinum Agents in Lung Cancer. Mol Cancer Ther. 2016;15:1669-81 pubmed publisher
Bas Orth C, Tan Y, Oliveira A, Bengtson C, Bading H. The calmodulin-binding transcription activator CAMTA1 is required for long-term memory formation in mice. Learn Mem. 2016;23:313-21 pubmed publisher
Meunier S, Timón K, Vernos I. Aurora-A regulates MCRS1 function during mitosis. Cell Cycle. 2016;15:1779-86 pubmed publisher
Denk F, Crow M, Didangelos A, Lopes D, McMahon S. Persistent Alterations in Microglial Enhancers in a Model of Chronic Pain. Cell Rep. 2016;15:1771-81 pubmed publisher
Sedlyarov V, Fallmann J, Ebner F, Huemer J, Sneezum L, Ivin M, et al. Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution. Mol Syst Biol. 2016;12:868 pubmed publisher
Kim D, Rhee S. Matrix metalloproteinase?2 regulates MDA?MB?231 breast cancer cell invasion induced by active mammalian diaphanous-related formin 1. Mol Med Rep. 2016;14:277-82 pubmed publisher
Stankovic Valentin N, Drzewicka K, König C, Schiebel E, Melchior F. Redox regulation of SUMO enzymes is required for ATM activity and survival in oxidative stress. EMBO J. 2016;35:1312-29 pubmed publisher
Homma Y, Fukuda M. Rabin8 regulates neurite outgrowth in both GEF activity-dependent and -independent manners. Mol Biol Cell. 2016;27:2107-18 pubmed publisher
Isono T, Chano T, Yonese J, Yuasa T. Therapeutic inhibition of mitochondrial function induces cell death in starvation-resistant renal cell carcinomas. Sci Rep. 2016;6:25669 pubmed publisher
Chauvigné F, Fjelldal P, Cerdà J, Finn R. Auto-Adhesion Potential of Extraocular Aqp0 during Teleost Development. PLoS ONE. 2016;11:e0154592 pubmed publisher
Yan M, Audet Walsh E, Manteghi S, Dufour C, WALKER B, Baba M, et al. Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1?/ERR?. Genes Dev. 2016;30:1034-46 pubmed publisher
Kim E, Ilic N, Shrestha Y, Zou L, Kamburov A, Zhu C, et al. Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles. Cancer Discov. 2016;6:714-26 pubmed publisher
Azevedo M, Schulman V, Folker E, Balakrishnan M, Baylies M. Imaging Approaches to Investigate Myonuclear Positioning in Drosophila. Methods Mol Biol. 2016;1411:291-312 pubmed publisher
McCubbin T, Bassil E, Zhang S, Blumwald E. Vacuolar Na?/H? NHX-Type Antiporters Are Required for Cellular K? Homeostasis, Microtubule Organization and Directional Root Growth. Plants (Basel). 2014;3:409-26 pubmed publisher
Nakamura R, Koshiba Takeuchi K, Tsuchiya M, Kojima M, Miyazawa A, Ito K, et al. Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice. Dev Growth Differ. 2016;58:367-82 pubmed publisher
Poburski D, Boerner J, Koenig M, Ristow M, Thierbach R. Time-resolved functional analysis of acute impairment of frataxin expression in an inducible cell model of Friedreich ataxia. Biol Open. 2016;5:654-61 pubmed publisher
Fellmeth J, Ghanaim E, Schindler K. Characterization of macrozoospermia-associated AURKC mutations in a mammalian meiotic system. Hum Mol Genet. 2016;25:2698-2711 pubmed
PETRUCCELLI E, Li Q, Rao Y, Kitamoto T. The Unique Dopamine/Ecdysteroid Receptor Modulates Ethanol-Induced Sedation in Drosophila. J Neurosci. 2016;36:4647-57 pubmed publisher
Frigola J, Iturbide A, Lopez Bigas N, Peiro S, González Pérez A. Altered oncomodules underlie chromatin regulatory factors driver mutations. Oncotarget. 2016;7:30748-59 pubmed publisher
Friese A, Faesen A, Huis In t Veld P, Fischböck J, Prumbaum D, Petrovic A, et al. Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin. Nat Commun. 2016;7:11407 pubmed publisher
Mendel I, Yacov N, Shoham A, Ishai E, Breitbart E. Treatment with Oxidized Phospholipids Directly Inhibits Nonalcoholic Steatohepatitis and Liver Fibrosis Without Affecting Steatosis. Dig Dis Sci. 2016;61:2545-53 pubmed publisher
Natsume T, Kiyomitsu T, Saga Y, Kanemaki M. Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors. Cell Rep. 2016;15:210-218 pubmed publisher
Park S, Piao Y, Thomas C, Fuller G, de Groot J. Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma. Oncotarget. 2016;7:26793-805 pubmed publisher
Michaels D, Leibowitz J, Azaiza M, Shil P, Shama S, Kutish G, et al. Cellular Microbiology of Mycoplasma canis. Infect Immun. 2016;84:1785-1795 pubmed publisher
Lassalle S, Zangari J, Popa A, Ilie M, Hofman V, Long E, et al. MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib. Oncotarget. 2016;7:30461-78 pubmed publisher
Noordenbos T, Blijdorp I, Chen S, Stap J, Mul E, Canete J, et al. Human mast cells capture, store, and release bioactive, exogenous IL-17A. J Leukoc Biol. 2016;100:453-62 pubmed publisher
Senbabaoglu F, Cingöz A, Kaya E, Kazancioglu S, Lack N, Acilan C, et al. Identification of Mitoxantrone as a TRAIL-sensitizing agent for Glioblastoma Multiforme. Cancer Biol Ther. 2016;17:546-57 pubmed publisher
Chan T, Hawkins C, Krieger J, McGlade C, Huang A. JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma. Cancer Res. 2016;76:2802-12 pubmed publisher
Nüsken E, Wohlfarth M, Lippach G, Rauh M, Schneider H, Dotsch J, et al. Reduced Perinatal Leptin Availability May Contribute to Adverse Metabolic Programming in a Rat Model of Uteroplacental Insufficiency. Endocrinology. 2016;157:1813-25 pubmed publisher
Tsokanos F, Albert M, Demetriades C, Spirohn K, Boutros M, Teleman A. eIF4A inactivates TORC1 in response to amino acid starvation. EMBO J. 2016;35:1058-76 pubmed publisher
Cyr Depauw C, Northey J, Tabariès S, Annis M, Dong Z, Cory S, et al. Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion. Mol Cell Biol. 2016;36:1509-25 pubmed publisher
Kudo S, Satoh K, Nogi M, Suzuki K, Sunamura S, Omura J, et al. SmgGDS as a Crucial Mediator of the Inhibitory Effects of Statins on Cardiac Hypertrophy and Fibrosis: Novel Mechanism of the Pleiotropic Effects of Statins. Hypertension. 2016;67:878-89 pubmed publisher
Tattoli I, Killackey S, Foerster E, Molinaro R, Maisonneuve C, Rahman M, et al. NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation. Cell Rep. 2016;14:2576-86 pubmed publisher
McKenney R, Huynh W, Vale R, Sirajuddin M. Tyrosination of α-tubulin controls the initiation of processive dynein-dynactin motility. EMBO J. 2016;35:1175-85 pubmed publisher
Vomund S, de Souza Silva M, Huston J, Korth C. Behavioral Resilience and Sensitivity to Locally Restricted Cortical Migration Deficits Induced by In Utero Knockdown of Disabled-1 in the Adult Rat. Cereb Cortex. 2017;27:2052-2063 pubmed publisher
Fukuda K, Miura Y, Maeda T, Hayashi S, Kurosaka M. Interleukin‑12B is upregulated by decoy receptor 3 in rheumatoid synovial fibroblasts. Mol Med Rep. 2016;13:3647-52 pubmed publisher
Remenyi J, Bajan S, Fuller Pace F, Arthur J, Hutvagner G. The loop structure and the RNA helicase p72/DDX17 influence the processing efficiency of the mice miR-132. Sci Rep. 2016;6:22848 pubmed publisher
Delgado E, Boisen M, Laskey R, Chen R, Song C, Sallit J, et al. High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome. Gynecol Oncol. 2016;141:348-356 pubmed publisher
Xu B, Washington A, Domeniconi R, Ferreira Souza A, Lu X, Sutherland A, et al. Protein tyrosine kinase 7 is essential for tubular morphogenesis of the Wolffian duct. Dev Biol. 2016;412:219-33 pubmed publisher
Song A, Gao T, Li P, Chen S, Guan Z, Wu D, et al. Transcriptome-Wide Identification and Expression Profiling of the DOF Transcription Factor Gene Family in Chrysanthemum morifolium. Front Plant Sci. 2016;7:199 pubmed publisher
Whitt J, Montgomery J, Meredith A. BK channel inactivation gates daytime excitability in the circadian clock. Nat Commun. 2016;7:10837 pubmed publisher
Yoshikawa R, Nakano Y, Yamada E, Izumi T, Misawa N, Koyanagi Y, et al. Species-specific differences in the ability of feline lentiviral Vif to degrade feline APOBEC3 proteins. Microbiol Immunol. 2016;60:272-9 pubmed publisher
Pattenden S, Simon J, Wali A, Jayakody C, Troutman J, McFadden A, et al. High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility. Proc Natl Acad Sci U S A. 2016;113:3018-23 pubmed publisher
McCallum K, Liu B, Fierro González J, Swoboda P, Arur S, Miranda Vizuete A, et al. TRX-1 Regulates SKN-1 Nuclear Localization Cell Non-autonomously in Caenorhabditis elegans. Genetics. 2016;203:387-402 pubmed publisher
Suzuki K, Satoh K, Ikeda S, Sunamura S, Otsuki T, Satoh T, et al. Basigin Promotes Cardiac Fibrosis and Failure in Response to Chronic Pressure Overload in Mice. Arterioscler Thromb Vasc Biol. 2016;36:636-46 pubmed publisher
Navarro R, Delgado Wicke P, Nuñez Prado N, Compte M, Blanco Toribio A, Nuñez G, et al. Role of nucleotide-binding oligomerization domain 1 (NOD1) in pericyte-mediated vascular inflammation. J Cell Mol Med. 2016;20:980-6 pubmed publisher
Kaczmarczyk L, Labrie Dion Ã, Sehgal K, Sylvester M, Skubal M, Josten M, et al. New Phosphospecific Antibody Reveals Isoform-Specific Phosphorylation of CPEB3 Protein. PLoS ONE. 2016;11:e0150000 pubmed publisher
Monzo P, Chong Y, Guetta Terrier C, Krishnasamy A, Sathe S, Yim E, et al. Mechanical confinement triggers glioma linear migration dependent on formin FHOD3. Mol Biol Cell. 2016;27:1246-61 pubmed publisher
Kim D, Jensen S, Noble K, Kc B, Roux K, Motamedchaboki K, et al. An improved smaller biotin ligase for BioID proximity labeling. Mol Biol Cell. 2016;27:1188-96 pubmed publisher
Taschner M, Weber K, Mourão A, Vetter M, Awasthi M, Stiegler M, et al. Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex. EMBO J. 2016;35:773-90 pubmed publisher
Pena D, Andrade V, Silva G, Neves J, Oliveira P, Alves M, et al. Rational design and validation of an anti-protein kinase C active-state specific antibody based on conformational changes. Sci Rep. 2016;6:22114 pubmed publisher
Sassone J, Taiana M, Lombardi R, Porretta Serapiglia C, Freschi M, Bonanno S, et al. ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin. Hum Mol Genet. 2016;25:1588-99 pubmed publisher
Kim D, Jung J, You E, Ko P, Oh S, Rhee S. mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization. Oncotarget. 2016;7:17829-43 pubmed publisher
Elagabani M, Briševac D, Kintscher M, Pohle J, Köhr G, Schmitz D, et al. Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation. J Biol Chem. 2016;291:9105-18 pubmed publisher
Devotta A, Juraver Geslin H, Gonzalez J, Hong C, Saint Jeannet J. Sf3b4-depleted Xenopus embryos: A model to study the pathogenesis of craniofacial defects in Nager syndrome. Dev Biol. 2016;415:371-382 pubmed publisher
Demetriades C, Plescher M, Teleman A. Lysosomal recruitment of TSC2 is a universal response to cellular stress. Nat Commun. 2016;7:10662 pubmed publisher
Reynolds A, Alvarez Y, Sasore T, Waghorne N, Butler C, Kilty C, et al. Phenotype-based Discovery of 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol as a Novel Regulator of Ocular Angiogenesis. J Biol Chem. 2016;291:7242-55 pubmed publisher
Li C, Xue C, Yang Q, Low B, Liou Y. NuSAP governs chromosome oscillation by facilitating the Kid-generated polar ejection force. Nat Commun. 2016;7:10597 pubmed publisher
Rao C, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, et al. Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice. Cancer Res. 2016;76:630-42 pubmed publisher
Vuković L, Jevtić P, Zhang Z, Stohr B, Levy D. Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding. J Cell Sci. 2016;129:1115-27 pubmed publisher
Baranski Z, Booij T, Kuijjer M, de Jong Y, Cleton Jansen A, Price L, et al. MEK inhibition induces apoptosis in osteosarcoma cells with constitutive ERK1/2 phosphorylation. Genes Cancer. 2015;6:503-12 pubmed
Haratake K, Sato A, Tsuruta F, Chiba T. KIAA0368-deficiency affects disassembly of 26S proteasome under oxidative stress condition. J Biochem. 2016;159:609-18 pubmed publisher
Durbin K, Fornelli L, Fellers R, Doubleday P, Narita M, Kelleher N. Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa. J Proteome Res. 2016;15:976-82 pubmed publisher
Takahashi J, Orcholski M, Yuan K, de Jesus Perez V. PDGF-dependent β-catenin activation is associated with abnormal pulmonary artery smooth muscle cell proliferation in pulmonary arterial hypertension. FEBS Lett. 2016;590:101-9 pubmed publisher
Evans D, Zhang H, Ham H, Pei H, Lee S, Kim J, et al. MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication. Cell Cycle. 2016;15:95-105 pubmed publisher
Mita T, Mayanagi T, Ichijo H, Fukumoto K, Otsuka K, Sakai A, et al. Docosahexaenoic Acid Promotes Axon Outgrowth by Translational Regulation of Tau and Collapsin Response Mediator Protein 2 Expression. J Biol Chem. 2016;291:4955-65 pubmed publisher
Dine J, O Sullivan C, Voeller D, Greer Y, Chavez K, Conway C, et al. The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl. Breast Cancer Res Treat. 2016;155:235-51 pubmed publisher
Ishikawa M, Williams G, Ikeuchi T, Sakai K, Fukumoto S, Yamada Y. Pannexin 3 and connexin 43 modulate skeletal development through their distinct functions and expression patterns. J Cell Sci. 2016;129:1018-30 pubmed publisher
Testoni E, Stephenson N, Torres Ayuso P, Marusiak A, Trotter E, Hudson A, et al. Somatically mutated ABL1 is an actionable and essential NSCLC survival gene. EMBO Mol Med. 2016;8:105-16 pubmed publisher
Hotta T, Fujita S, Uchimura S, Noguchi M, Demura T, Muto E, et al. Affinity Purification and Characterization of Functional Tubulin from Cell Suspension Cultures of Arabidopsis and Tobacco. Plant Physiol. 2016;170:1189-205 pubmed publisher
Hall J, Seedarala S, Zhao H, Garg G, Ghosh S, Blagg B. Novobiocin Analogues That Inhibit the MAPK Pathway. J Med Chem. 2016;59:925-33 pubmed publisher
Qi J, Dong Z, Liu J, Peery R, Zhang S, Liu J, et al. Effective Targeting of the Survivin Dimerization Interface with Small-Molecule Inhibitors. Cancer Res. 2016;76:453-62 pubmed publisher
Naylor R, Jeganathan K, Cao X, van Deursen J. Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy. J Clin Invest. 2016;126:543-59 pubmed publisher
Fusco L, Lefort R, Smith K, Benmansour F, Gonzalez G, Barillari C, et al. Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling. J Cell Biol. 2016;212:91-111 pubmed publisher
Yamaguchi T, Lu C, Ida L, Yanagisawa K, Usukura J, Cheng J, et al. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. Nat Commun. 2016;7:10060 pubmed publisher
Kim S, Park S, Shim S, Park S, Kim K, Jeong S, et al. Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells. PLoS ONE. 2015;10:e0146073 pubmed publisher
González Wusener A, González Ã, Nakamura F, Arregui C. PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility. Biol Open. 2015;5:32-44 pubmed publisher
Bua S, Sotiropoulou P, Sgarlata C, Borlado L, Eguren M, Dominguez O, et al. Deregulated expression of Cdc6 in the skin facilitates papilloma formation and affects the hair growth cycle. Cell Cycle. 2015;14:3897-907 pubmed publisher
Uddin B, Chen N, Panic M, Schiebel E. Genome editing through large insertion leads to the skipping of targeted exon. BMC Genomics. 2015;16:1082 pubmed publisher
Chen T, Syu J, Lin T, Cheng H, Lu F, Wang C. Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells. Oncogenesis. 2015;4:e180 pubmed publisher
Petrova N, Velichko A, Razin S, Kantidze O. Early S-phase cell hypersensitivity to heat stress. Cell Cycle. 2016;15:337-44 pubmed publisher
García V, Lara Chica M, Cantarero I, Sterner O, Calzado M, Muñoz E. Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells. Oncotarget. 2016;7:4490-506 pubmed publisher
Catalano V, Dentice M, Ambrosio R, Luongo C, Carollo R, Benfante A, et al. Activated Thyroid Hormone Promotes Differentiation and Chemotherapeutic Sensitization of Colorectal Cancer Stem Cells by Regulating Wnt and BMP4 Signaling. Cancer Res. 2016;76:1237-44 pubmed publisher
Babbitt D, Kim J, Forrester S, Brown M, Park J. Effect of Interleukin-10 and Laminar Shear Stress on Endothelial Nitric Oxide Synthase and Nitric Oxide in African American Human Umbilical Vein Endothelial Cells. Ethn Dis. 2015;25:413-8 pubmed publisher
Gong N, Jönsson E, Björnsson B. Acute anorexigenic action of leptin in rainbow trout is mediated by the hypothalamic Pi3k pathway. J Mol Endocrinol. 2016;56:227-38 pubmed publisher
Boese A, Saba R, Campbell K, Majer A, Medina S, Burton L, et al. MicroRNA abundance is altered in synaptoneurosomes during prion disease. Mol Cell Neurosci. 2016;71:13-24 pubmed publisher
Jones C, Pashler A, Towler B, Robinson S, Newbury S. RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1. Nucleic Acids Res. 2016;44:267-80 pubmed publisher
Nomakuchi T, Rigo F, Aznarez I, Krainer A. Antisense oligonucleotide-directed inhibition of nonsense-mediated mRNA decay. Nat Biotechnol. 2016;34:164-6 pubmed publisher
Jemaà M, Manic G, Lledo G, Lissa D, Reynès C, Morin N, et al. Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition. Oncotarget. 2016;7:885-901 pubmed publisher
Debruhl H, Albertson R, Swider Z, Sullivan W. Rop, the Sec1/Munc18 homolog in Drosophila, is required for furrow ingression and stable cell shape during cytokinesis. J Cell Sci. 2016;129:430-43 pubmed publisher
Passaro C, Borriello F, Vastolo V, Di Somma S, Scamardella E, Gigantino V, et al. The oncolytic virus dl922-947 reduces IL-8/CXCL8 and MCP-1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma. Oncotarget. 2016;7:1500-15 pubmed publisher
Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, et al. Branched-chain amino acid catabolism is a conserved regulator of physiological ageing. Nat Commun. 2015;6:10043 pubmed publisher
Ryu H, Chung M, Dobrzyński M, Fey D, Blum Y, Lee S, et al. Frequency modulation of ERK activation dynamics rewires cell fate. Mol Syst Biol. 2015;11:838 pubmed publisher
Delépine C, Meziane H, Nectoux J, Opitz M, Smith A, Ballatore C, et al. Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes. Hum Mol Genet. 2016;25:146-57 pubmed publisher
van Adrichem A, Wennerberg K. MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity. FEBS Lett. 2015;589:3859-65 pubmed publisher
Geng J, Xia L, Li W, Zhao C, Dou F. Cycloheximide Treatment Causes a ZVAD-Sensitive Protease-Dependent Cleavage of Human Tau in Drosophila Cells. J Alzheimers Dis. 2016;49:1161-8 pubmed publisher
Hegemann B, Unger M, Lee S, Stoffel Studer I, van den Heuvel J, Pelet S, et al. A Cellular System for Spatial Signal Decoding in Chemical Gradients. Dev Cell. 2015;35:458-70 pubmed publisher
Yang Z, Hong L, Follett J, Wabitsch M, Hamilton N, Collins B, et al. Functional characterization of retromer in GLUT4 storage vesicle formation and adipocyte differentiation. FASEB J. 2016;30:1037-50 pubmed publisher
Boj M, Chauvigné F, Zapater C, Cerdà J. Gonadotropin-Activated Androgen-Dependent and Independent Pathways Regulate Aquaporin Expression during Teleost (Sparus aurata) Spermatogenesis. PLoS ONE. 2015;10:e0142512 pubmed publisher
Sekine H, Okazaki K, Ota N, Shima H, Katoh Y, Suzuki N, et al. The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression. Mol Cell Biol. 2016;36:407-20 pubmed publisher
Ukken F, Bruckner J, Weir K, Hope S, Sison S, Birschbach R, et al. BAR-SH3 sorting nexins are conserved interacting proteins of Nervous wreck that organize synapses and promote neurotransmission. J Cell Sci. 2016;129:166-77 pubmed publisher
Ribeiro M, López de Figueroa P, Blanco F, Mendes A, Caramés B. Insulin decreases autophagy and leads to cartilage degradation. Osteoarthritis Cartilage. 2016;24:731-9 pubmed publisher
Hori A, Morand A, Ikebe C, Frith D, Snijders A, Toda T. The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation. Biochem Biophys Res Commun. 2015;468:39-45 pubmed publisher
Xing L, Son J, Stevenson T, Lillesaar C, Bally Cuif L, Dahl T, et al. A Serotonin Circuit Acts as an Environmental Sensor to Mediate Midline Axon Crossing through EphrinB2. J Neurosci. 2015;35:14794-808 pubmed publisher
Takeuchi J, Ren F, Yoshikawa R, Yamada E, Nakano Y, Kobayashi T, et al. Coevolutionary dynamics between tribe Cercopithecini tetherins and their lentiviruses. Sci Rep. 2015;5:16021 pubmed publisher
Austen K, Ringer P, Mehlich A, Chrostek Grashoff A, Kluger C, Klingner C, et al. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015;17:1597-606 pubmed publisher
Mizutani A, Koinuma D, Seimiya H, Miyazono K. The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma. Oncogene. 2016;35:3514-23 pubmed publisher
Tcherniuk S, Chesnokova O, Oleinikov I, Potopalsky A, Oleinikov A. Anti-malarial effect of semi-synthetic drug amitozyn. Malar J. 2015;14:425 pubmed publisher
Tavecchio M, Lisanti S, Bennett M, Languino L, Altieri D. Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism. Sci Rep. 2015;5:15981 pubmed publisher
Goto Y, Yajima I, Kumasaka M, Ohgami N, Tanaka A, Tsuzuki T, et al. Transcription factor LSF (TFCP2) inhibits melanoma growth. Oncotarget. 2016;7:2379-90 pubmed publisher
Chinen T, Liu P, Shioda S, Pagel J, Cerikan B, Lin T, et al. The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle. Nat Commun. 2015;6:8722 pubmed publisher
Manivannan S, Jacobsen T, Lyon P, Selvaraj B, Halpin P, Simcox A. Targeted Integration of Single-Copy Transgenes in Drosophila melanogaster Tissue-Culture Cells Using Recombination-Mediated Cassette Exchange. Genetics. 2015;201:1319-28 pubmed publisher
Adrados I, Larrasa Alonso J, Galarreta A, López Antona I, Menéndez C, Abad M, et al. The homeoprotein SIX1 controls cellular senescence through the regulation of p16INK4A and differentiation-related genes. Oncogene. 2016;35:3485-94 pubmed publisher
Zhang J, Wang C, Chen X, Takada M, Fan C, Zheng X, et al. EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer. EMBO J. 2015;34:2953-70 pubmed publisher
Yoshikawa R, Izumi T, Yamada E, Nakano Y, Misawa N, Ren F, et al. A Naturally Occurring Domestic Cat APOBEC3 Variant Confers Resistance to Feline Immunodeficiency Virus Infection. J Virol. 2016;90:474-85 pubmed publisher
Mayanagi T, Yasuda H, Sobue K. PSD-Zip70 Deficiency Causes Prefrontal Hypofunction Associated with Glutamatergic Synapse Maturation Defects by Dysregulation of Rap2 Activity. J Neurosci. 2015;35:14327-40 pubmed publisher
Chen J, Kao L, Jana S, Sivan Loukianova E, Mendonça S, Cabrera O, et al. Rootletin organizes the ciliary rootlet to achieve neuron sensory function in Drosophila. J Cell Biol. 2015;211:435-53 pubmed publisher
Smith C, D Mello S. Cell and Context-Dependent Effects of the Heat Shock Protein DNAJB6 on Neuronal Survival. Mol Neurobiol. 2016;53:5628-39 pubmed publisher
Erami Z, Timpson P, Yao W, Zaidel Bar R, Anderson K. There are four dynamically and functionally distinct populations of E-cadherin in cell junctions. Biol Open. 2015;4:1481-9 pubmed publisher
Chatterjee S, Saj A, Gocha T, Murphy M, Gonsalves F, Zhang X, et al. Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells. J Cell Biol. 2015;211:39-51 pubmed publisher
Xiao L, Zhou D, Tan R, Fu H, Zhou L, Hou F, et al. Sustained Activation of Wnt/?-Catenin Signaling Drives AKI to CKD Progression. J Am Soc Nephrol. 2016;27:1727-40 pubmed publisher
Ragot A, Pietropaolo S, Vincent J, Delage P, Zhang H, Allinquant B, et al. Genetic deletion of the Histone Deacetylase 6 exacerbates selected behavioral deficits in the R6/1 mouse model for Huntington's disease. Brain Behav. 2015;5:e00361 pubmed publisher
Lim C, Gandhi S, Biniossek M, Feng L, Schilling O, Urban S, et al. An Aminopeptidase in the Drosophila Testicular Niche Acts in Germline Stem Cell Maintenance and Spermatogonial Dedifferentiation. Cell Rep. 2015;13:315-25 pubmed publisher
Jiang S, Du J, Kong Q, Li C, Li Y, Sun H, et al. A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation. PLoS ONE. 2015;10:e0139830 pubmed publisher
Lafave L, Beguelin W, Koche R, Teater M, Spitzer B, Chramiec A, et al. Loss of BAP1 function leads to EZH2-dependent transformation. Nat Med. 2015;21:1344-9 pubmed publisher
Cheishvili D, Stefanska B, Yi C, Li C, Yu P, Arakelian A, et al. A common promoter hypomethylation signature in invasive breast, liver and prostate cancer cell lines reveals novel targets involved in cancer invasiveness. Oncotarget. 2015;6:33253-68 pubmed publisher
Walker Caulfield M, Guo Y, Johnson R, McCarthy C, Fitz Gibbon P, Lucchinetti C, et al. NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG. J Neuroinflammation. 2015;12:185 pubmed publisher
Lagarrigue F, Vikas Anekal P, Lee H, Bachir A, Ablack J, Horwitz A, et al. A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. Nat Commun. 2015;6:8492 pubmed publisher
Khan M, LANG M, Huang M, Raymond A, Bond V, Shiramizu B, et al. Nef exosomes isolated from the plasma of individuals with HIV-associated dementia (HAD) can induce Aβ(1-42) secretion in SH-SY5Y neural cells. J Neurovirol. 2016;22:179-90 pubmed publisher
Sorrell S, Golder Z, Johnstone D, Frankl F. Renal peroxiredoxin 6 interacts with anion exchanger 1 and plays a novel role in pH homeostasis. Kidney Int. 2016;89:105-112 pubmed publisher
Sumiyoshi E, Fukata Y, Namai S, Sugimoto A. Caenorhabditis elegans Aurora A kinase is required for the formation of spindle microtubules in female meiosis. Mol Biol Cell. 2015;26:4187-96 pubmed publisher
Wang S, Wu D, Quintin S, Green R, Cheerambathur D, Ochoa S, et al. NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans. elife. 2015;4:e08649 pubmed publisher
Renaud L, Harris L, Mani S, Kasiganesan H, CHOU J, Baicu C, et al. HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis. Circ Heart Fail. 2015;8:1094-104 pubmed publisher
Schnerch D, Nigg E. Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres. Oncogene. 2016;35:2711-22 pubmed publisher
Love J, Shah S. Ribosomal trafficking is reduced in Schwann cells following induction of myelination. Front Cell Neurosci. 2015;9:306 pubmed publisher
Wynne D, Funabiki H. Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components. J Cell Biol. 2015;210:899-916 pubmed
Miyazaki Y, Chen L, Chu B, Swigut T, Wandless T. Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells. elife. 2015;4: pubmed publisher
Torres Ayuso P, Tello Lafoz M, Mérida I, Ávila Flores A. Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1. Oncogenesis. 2015;4:e164 pubmed publisher
Gao Y, Li Z, Gabrielsen J, Simcox J, Lee S, Jones D, et al. Adipocyte iron regulates leptin and food intake. J Clin Invest. 2015;125:3681-91 pubmed publisher
Ragot T, Provost C, Prignon A, Cohen R, Lepoivre M, Lausson S. Apoptosis induction by combination of drugs or a conjugated molecule associating non-steroidal anti-inflammatory and nitric oxide donor effects in medullary thyroid cancer models: implication of the tumor suppressor p73. Thyroid Res. 2015;8:13 pubmed publisher
Meunier S, Shvedunova M, Van Nguyen N, Avila L, Vernos I, Akhtar A. An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis. Nat Commun. 2015;6:7889 pubmed publisher
Liao X, Zhang R, Lu Y, Prosdocimo D, Sangwung P, Zhang L, et al. Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis. J Clin Invest. 2015;125:3461-76 pubmed publisher
Fu J, Bian M, Xin G, Deng Z, Luo J, Guo X, et al. TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux. J Cell Biol. 2015;210:373-83 pubmed publisher
Zhuo W, Ge W, Meng G, Jia S, Zhou X, Liu J. MicroRNA‑20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing early growth response 2 expression. Mol Med Rep. 2015;12:4989-94 pubmed publisher
Jiang Y, Qian X, Shen J, Wang Y, Li X, Liu R, et al. Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation. Nat Cell Biol. 2015;17:1158-68 pubmed publisher
Ahn J, Li J, Chen E, Kent D, Park H, Green A. JAK2V617F mediates resistance to DNA damage-induced apoptosis by modulating FOXO3A localization and Bcl-xL deamidation. Oncogene. 2016;35:2235-46 pubmed publisher
Mizunoya W, Miyahara H, Okamoto S, Akahoshi M, Suzuki T, Do M, et al. Improvement of Endurance Based on Muscle Fiber-Type Composition by Treatment with Dietary Apple Polyphenols in Rats. PLoS ONE. 2015;10:e0134303 pubmed publisher
Poggianella M, Slon Campos J, Chan K, Tan H, Bestagno M, Ooi E, et al. Dengue E Protein Domain III-Based DNA Immunisation Induces Strong Antibody Responses to All Four Viral Serotypes. PLoS Negl Trop Dis. 2015;9:e0003947 pubmed publisher
Mellone M, Stanic J, Hernandez L, Iglesias E, Zianni E, Longhi A, et al. NMDA receptor GluN2A/GluN2B subunit ratio as synaptic trait of levodopa-induced dyskinesias: from experimental models to patients. Front Cell Neurosci. 2015;9:245 pubmed publisher
Takenaka N, Sumi Y, Matsuda K, Fujita J, Hosooka T, Noguchi T, et al. Role for RalA downstream of Rac1 in skeletal muscle insulin signalling. Biochem J. 2015;469:445-54 pubmed publisher
Mitani T, Minami M, Harada N, Ashida H, Yamaji R. Autophagic degradation of the androgen receptor mediated by increased phosphorylation of p62 suppresses apoptosis in hypoxia. Cell Signal. 2015;27:1994-2001 pubmed publisher
Trakala M, Partida D, Salazar Roa M, Maroto M, Wachowicz P, de Cárcer G, et al. Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice. Blood. 2015;126:1707-14 pubmed publisher
Wu S, Li L, Kopp N, Montero J, Chapuy B, Yoda A, et al. Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2015;28:29-41 pubmed publisher
Amin N, Womble M, Ledón Rettig C, Hull M, Dickinson A, Nascone Yoder N. Budgett's frog (Lepidobatrachus laevis): A new amphibian embryo for developmental biology. Dev Biol. 2015;405:291-303 pubmed publisher
Han X, Adames K, Sykes E, Srayko M. The KLP-7 Residue S546 Is a Putative Aurora Kinase Site Required for Microtubule Regulation at the Centrosome in C. elegans. PLoS ONE. 2015;10:e0132593 pubmed publisher
Mahdipour M, Leitoguinho A, Zacarias Silva R, van Tol H, Stout T, Rodrigues G, et al. TACC3 Is Important for Correct Progression of Meiosis in Bovine Oocytes. PLoS ONE. 2015;10:e0132591 pubmed publisher
Hashimoto M, Bacman S, Peralta S, Falk M, Chomyn A, Chan D, et al. MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases. Mol Ther. 2015;23:1592-9 pubmed publisher
Selfridge A, Hyun N, Chiang C, Reyna S, Weissmiller A, Shi L, et al. Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy. Neurophotonics. 2015;2:015006 pubmed publisher
Siriwardana N, Meyer R, Panchenko M. The novel function of JADE1S in cytokinesis of epithelial cells. Cell Cycle. 2015;14:2821-34 pubmed publisher
Tsalikis J, Tattoli I, Ling A, Sorbara M, Croitoru D, Philpott D, et al. Intracellular Bacterial Pathogens Trigger the Formation of U Small Nuclear RNA Bodies (U Bodies) through Metabolic Stress Induction. J Biol Chem. 2015;290:20904-18 pubmed publisher
Klare K, Weir J, Basilico F, Zimniak T, Massimiliano L, Ludwigs N, et al. CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores. J Cell Biol. 2015;210:11-22 pubmed publisher
Chou C, Loh J, Yang M, Lin C, Hong M, Cho C, et al. AIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1. Cell Cycle. 2015;14:2764-76 pubmed publisher
Qi R, Xu N, Wang G, Ren H, Li S, Lei J, et al. The lamin-A/C-LAP2α-BAF1 protein complex regulates mitotic spindle assembly and positioning. J Cell Sci. 2015;128:2830-41 pubmed publisher
Taylor S, Dantas T, Durán I, Wu S, Lachman R, Nelson S, et al. Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome. Nat Commun. 2015;6:7092 pubmed publisher
Bondeson D, Mares A, Smith I, Ko E, Campos S, Miah A, et al. Catalytic in vivo protein knockdown by small-molecule PROTACs. Nat Chem Biol. 2015;11:611-7 pubmed publisher
Bosen F, Celli A, Crumrine D, Vom Dorp K, Ebel P, Jastrow H, et al. Altered epidermal lipid processing and calcium distribution in the KID syndrome mouse model Cx26S17F. FEBS Lett. 2015;589:1904-10 pubmed publisher
Nakano Y, Matsuda K, Yoshikawa R, Yamada E, Misawa N, Hirsch V, et al. Down-modulation of primate lentiviral receptors by Nef proteins of simian immunodeficiency virus (SIV) of chimpanzees (SIVcpz) and related SIVs: implication for the evolutionary event at the emergence of SIVcpz. J Gen Virol. 2015;96:2867-2877 pubmed publisher
Deloulme J, Gory Fauré S, Mauconduit F, Chauvet S, Jonckheere J, Boulan B, et al. Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth. Nat Commun. 2015;6:7246 pubmed publisher
Amin A, Rajan S, Liang W, Pongtornpipat P, Groysman M, Tapia E, et al. Evidence Suggesting That Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors. Cancer Res. 2015;75:2916-27 pubmed publisher
Fellmeth J, Gordon D, Robins C, Scott R, Treff N, Schindler K. Expression and characterization of three Aurora kinase C splice variants found in human oocytes. Mol Hum Reprod. 2015;21:633-44 pubmed publisher
Pohlmann T, Baumann S, Haag C, Albrecht M, Feldbrügge M. A FYVE zinc finger domain protein specifically links mRNA transport to endosome trafficking. elife. 2015;4: pubmed publisher
Hong X, Sin W, Harris A, Naus C. Gap junctions modulate glioma invasion by direct transfer of microRNA. Oncotarget. 2015;6:15566-77 pubmed
Motiño O, Francés D, Mayoral R, Castro Sánchez L, Fernández Velasco M, Boscá L, et al. Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver Is DEAD-Box Helicase p68 (DDX5) Dependent: Role in Insulin Signaling. Mol Cell Biol. 2015;35:2554-67 pubmed publisher
Matrka M, Hennigan R, Kappes F, DeLay M, Lambert P, Aronow B, et al. DEK over-expression promotes mitotic defects and micronucleus formation. Cell Cycle. 2015;14:3939-53 pubmed publisher
VEGA RODRIGUEZ J, Perez Barreto D, Ruiz Reyes A, Jacobs Lorena M. Targeting molecular interactions essential for Plasmodium sexual reproduction. Cell Microbiol. 2015;17:1594-604 pubmed publisher
Sengupta D, Kannan A, Kern M, Moreno M, Vural E, Stack B, et al. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma. Epigenetics. 2015;10:460-6 pubmed publisher
Lian A, Hains P, Sarcevic B, Robinson P, Chircop M. IQGAP1 is associated with nuclear envelope reformation and completion of abscission. Cell Cycle. 2015;14:2058-74 pubmed publisher
Gau D, Lesnock J, Hood B, Bhargava R, Sun M, Darcy K, et al. BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility - A proteomics study. Cell Cycle. 2015;14:1884-92 pubmed publisher
Suzuki S, Nozawa Y, Tsukamoto S, Kaneko T, Imai H, Minami N. Histone methyltransferase Smyd3 regulates early embryonic lineage commitment in mice. Reproduction. 2015;150:21-30 pubmed publisher
Caparrós Martín J, De Luca A, Cartault F, Aglan M, Temtamy S, Otaify G, et al. Specific variants in WDR35 cause a distinctive form of Ellis-van Creveld syndrome by disrupting the recruitment of the EvC complex and SMO into the cilium. Hum Mol Genet. 2015;24:4126-37 pubmed publisher
Towler B, Jones C, Viegas S, Apura P, Waldron J, Smalley S, et al. The 3'-5' exoribonuclease Dis3 regulates the expression of specific microRNAs in Drosophila wing imaginal discs. RNA Biol. 2015;12:728-41 pubmed publisher
Gupta J, Igea A, Papaioannou M, López Casas P, Llonch E, Hidalgo M, et al. Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors. Oncotarget. 2015;6:8539-51 pubmed
Kukharsky M, Quintiero A, Matsumoto T, Matsukawa K, An H, Hashimoto T, et al. Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis. Mol Neurodegener. 2015;10:20 pubmed publisher
Selvaraj N, Kedage V, Hollenhorst P. Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells. Cell Commun Signal. 2015;13:12 pubmed publisher
Hemmasi S, Czulkies B, Schorch B, Veit A, Aktories K, Papatheodorou P. Interaction of the Clostridium difficile Binary Toxin CDT and Its Host Cell Receptor, Lipolysis-stimulated Lipoprotein Receptor (LSR). J Biol Chem. 2015;290:14031-44 pubmed publisher
Jimenez Sanchez M, Lam W, Hannus M, Sönnichsen B, Imarisio S, Fleming A, et al. siRNA screen identifies QPCT as a druggable target for Huntington's disease. Nat Chem Biol. 2015;11:347-354 pubmed publisher
Stuart B, Choi J, Zaidi S, Xing C, Holohan B, Chen R, et al. Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening. Nat Genet. 2015;47:512-7 pubmed publisher
Schmid C, Robinson M, Scheifinger N, Müller S, Cogliatti S, Tzankov A, et al. DUSP4 deficiency caused by promoter hypermethylation drives JNK signaling and tumor cell survival in diffuse large B cell lymphoma. J Exp Med. 2015;212:775-92 pubmed publisher
Waldron J, Jones C, Towler B, Pashler A, Grima D, Hebbes S, et al. Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper. Biol Open. 2015;4:649-60 pubmed publisher
Borriello F, Longo M, Spinelli R, Pecoraro A, Granata F, Staiano R, et al. IL-3 synergises with basophil-derived IL-4 and IL-13 to promote the alternative activation of human monocytes. Eur J Immunol. 2015;45:2042-51 pubmed publisher
Florimond C, Sahin A, Vidilaseris K, Dong G, Landrein N, Dacheux D, et al. BILBO1 is a scaffold protein of the flagellar pocket collar in the pathogen Trypanosoma brucei. PLoS Pathog. 2015;11:e1004654 pubmed publisher
Groen C, Jayo A, Parsons M, Tootle T. Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture. Mol Biol Cell. 2015;26:1901-17 pubmed publisher
Yusuf N, Green J, Wall R, Knuepfer E, Moon R, Schulte Huxel C, et al. The Plasmodium Class XIV Myosin, MyoB, Has a Distinct Subcellular Location in Invasive and Motile Stages of the Malaria Parasite and an Unusual Light Chain. J Biol Chem. 2015;290:12147-64 pubmed publisher
Čajánek L, Glatter T, Nigg E. The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis. J Cell Sci. 2015;128:1674-82 pubmed publisher
Filou S, Korpetinou A, Kyriakopoulou D, Bounias D, Stavropoulos M, Ravazoula P, et al. ADAMTS expression in colorectal cancer. PLoS ONE. 2015;10:e0121209 pubmed publisher
Jacovetti C, Jimenez V, Ayuso E, Laybutt R, Peyot M, Prentki M, et al. Contribution of Intronic miR-338-3p and Its Hosting Gene AATK to Compensatory β-Cell Mass Expansion. Mol Endocrinol. 2015;29:693-702 pubmed publisher
Kern U, Wischnewski V, Biniossek M, Schilling O, Reinheckel T. Lysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells. Mol Cancer. 2015;14:39 pubmed publisher
Ishikawa T, Adachi S, Okayama T, Kokura S, Mizushima K, Doi T, et al. Cytotoxic T lymphocyte-associated antigen 4 inhibition increases the antitumor activity of adoptive T-cell therapy when carried out with naïve rather than differentiated T cells. Oncol Rep. 2015;33:2545-52 pubmed publisher
Teplyuk N, Uhlmann E, Wong A, Karmali P, Basu M, Gabriely G, et al. MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma. Oncotarget. 2015;6:3770-83 pubmed
Bouris P, Skandalis S, Piperigkou Z, Afratis N, Karamanou K, Aletras A, et al. Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells. Matrix Biol. 2015;43:42-60 pubmed publisher
Nunes A, Alves M, Tomás G, Conde V, Cristóvão A, Moreira P, et al. Daily consumption of white tea (Camellia sinensis (L.)) improves the cerebral cortex metabolic and oxidative profile in prediabetic Wistar rats. Br J Nutr. 2015;113:832-42 pubmed publisher
Moreau P, Moreau K, Segarra A, Tourbiez D, Travers M, Rubinsztein D, et al. Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections. Autophagy. 2015;11:516-26 pubmed publisher
Sanjurjo L, Amézaga N, Aran G, Naranjo Gómez M, Arias L, Armengol C, et al. The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses. Autophagy. 2015;11:487-502 pubmed publisher
Amodeo A, Jukam D, Straight A, Skotheim J. Histone titration against the genome sets the DNA-to-cytoplasm threshold for the Xenopus midblastula transition. Proc Natl Acad Sci U S A. 2015;112:E1086-95 pubmed publisher
Wong V, Wu A, Wang J, Liu L, Law B. Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy. Molecules. 2015;20:3496-514 pubmed publisher
Postberg J, Kanders M, Forcob S, Willems R, Orth V, Hensel K, et al. CpG signalling, H2A.Z/H3 acetylation and microRNA-mediated deferred self-attenuation orchestrate foetal NOS3 expression. Clin Epigenetics. 2015;7:9 pubmed publisher
Chen R, Xu M, Nagati J, Hogg R, Das A, Gerard R, et al. The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment. PLoS ONE. 2015;10:e0116515 pubmed publisher
Diamond M, Cai S, Boudreau A, Carey C, Lyle N, Pappu R, et al. Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1. J Biol Chem. 2015;290:9075-86 pubmed publisher
Dacheux D, Roger B, Bosc C, Landrein N, Roche E, Chansel L, et al. Human FAM154A (SAXO1) is a microtubule-stabilizing protein specific to cilia and related structures. J Cell Sci. 2015;128:1294-307 pubmed publisher
Brookes E, Laurent B, Õunap K, Carroll R, Moeschler J, Field M, et al. Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity. Hum Mol Genet. 2015;24:2861-72 pubmed publisher
Leoni G, Neumann P, Kamaly N, Quirós M, Nishio H, Jones H, et al. Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest. 2015;125:1215-27 pubmed publisher
Shah M, Rennoll S, Raup Konsavage W, Yochum G. A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells. Cell Cycle. 2015;14:323-32 pubmed publisher
Matsuda M, Koga M, Woltjen K, Nishida E, Ebisuya M. Synthetic lateral inhibition governs cell-type bifurcation with robust ratios. Nat Commun. 2015;6:6195 pubmed publisher
Kimura S, Loppin B. Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes. Open Biol. 2015;5:140145 pubmed publisher
Valença I, Pértega Gomes N, Vizcaino J, Henrique R, Lopes C, Baltazar F, et al. Localization of MCT2 at peroxisomes is associated with malignant transformation in prostate cancer. J Cell Mol Med. 2015;19:723-33 pubmed publisher
Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, et al. A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages. Genes Dev. 2015;29:394-408 pubmed publisher
White R, Zemen B, Khan Z, Montgomery J, Herrera G, Meredith A. Evaluation of mouse urinary bladder smooth muscle for diurnal differences in contractile properties. Front Pharmacol. 2014;5:293 pubmed publisher
Overlack K, Primorac I, Vleugel M, Krenn V, Maffini S, Hoffmann I, et al. A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint. elife. 2015;4:e05269 pubmed publisher
Kim S, Yu H. Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores. J Cell Biol. 2015;208:181-96 pubmed publisher
Rawat V, Goux W, Piechaczyk M, D Mello S. c-Fos Protects Neurons Through a Noncanonical Mechanism Involving HDAC3 Interaction: Identification of a 21-Amino Acid Fragment with Neuroprotective Activity. Mol Neurobiol. 2016;53:1165-80 pubmed publisher
Gaume X, Tassin A, Ugrinova I, Mongelard F, Monier K, Bouvet P. Centrosomal nucleolin is required for microtubule network organization. Cell Cycle. 2015;14:902-19 pubmed publisher
Johnson A, Bhattacharya N, Hanna M, Pennington J, Schuh A, Wang L, et al. TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization. EMBO J. 2015;34:811-27 pubmed publisher
Chauvigné F, Boj M, Finn R, Cerdà J. Mitochondrial aquaporin-8-mediated hydrogen peroxide transport is essential for teleost spermatozoon motility. Sci Rep. 2015;5:7789 pubmed publisher
The I, Ruijtenberg S, Bouchet B, Cristobal A, Prinsen M, van Mourik T, et al. Rb and FZR1/Cdh1 determine CDK4/6-cyclin D requirement in C. elegans and human cancer cells. Nat Commun. 2015;6:5906 pubmed publisher
Lipinszki Z, Lefevre S, Savoian M, Singleton M, Glover D, Przewloka M. Centromeric binding and activity of Protein Phosphatase 4. Nat Commun. 2015;6:5894 pubmed publisher
Lavagnolli T, Gupta P, Hörmanseder E, Mira Bontenbal H, Dharmalingam G, Carroll T, et al. Initiation and maintenance of pluripotency gene expression in the absence of cohesin. Genes Dev. 2015;29:23-38 pubmed publisher
Isgor C, Pare C, McDole B, Coombs P, Guthrie K. Expansion of the dentate mossy fiber-CA3 projection in the brain-derived neurotrophic factor-enriched mouse hippocampus. Neuroscience. 2015;288:10-23 pubmed publisher
Sierra Fonseca J, Najera O, Martinez Jurado J, Walker E, Varela Ramirez A, Khan A, et al. Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction. BMC Neurosci. 2014;15:132 pubmed publisher
Iaconelli J, Huang J, Berkovitch S, Chattopadhyay S, Mazitschek R, Schreiber S, et al. HDAC6 inhibitors modulate Lys49 acetylation and membrane localization of β-catenin in human iPSC-derived neuronal cells. ACS Chem Biol. 2015;10:883-90 pubmed publisher
Marthandan S, Priebe S, Hemmerich P, Klement K, Diekmann S. Long-term quiescent fibroblast cells transit into senescence. PLoS ONE. 2014;9:e115597 pubmed publisher
Schulman V, Folker E, Rosen J, Baylies M. Syd/JIP3 and JNK signaling are required for myonuclear positioning and muscle function. PLoS Genet. 2014;10:e1004880 pubmed publisher
Tseng C, Kao S, Wan C, Cho Y, Tung S, Hsu H. Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche. PLoS Genet. 2014;10:e1004888 pubmed publisher
Wiesauer I, Gaumannmüller C, Steinparzer I, Strobl B, Kovarik P. Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription. Mol Cell Biol. 2015;35:716-27 pubmed publisher
Müller J, Krijgsman O, Tsoi J, Robert L, Hugo W, Song C, et al. Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma. Nat Commun. 2014;5:5712 pubmed publisher
Ward C, Boggio K, Johnson B, Boyd J, Douthwright S, Shaffer S, et al. A loss of FUS/TLS function leads to impaired cellular proliferation. Cell Death Dis. 2014;5:e1572 pubmed publisher
Chroscinski D, Sampey D, Hewitt A. Registered report: Melanoma genome sequencing reveals frequent PREX2 mutations. elife. 2014;3: pubmed publisher
Steinmetz B, Hackl H, Slabáková E, Schwarzinger I, Smějová M, Spittler A, et al. The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid. Cell Cycle. 2014;13:2931-43 pubmed publisher
Mitter S, Song C, Qi X, Mao H, Rao H, Akin D, et al. Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. Autophagy. 2014;10:1989-2005 pubmed publisher
van Adrichem A, Fagerholm A, Turunen L, Lehto A, Saarela J, Koskinen A, et al. Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP. Comb Chem High Throughput Screen. 2015;18:3-17 pubmed
Tripathy S, Weil S, Chen C, Anand P, Vallee R, Gross S. Autoregulatory mechanism for dynactin control of processive and diffusive dynein transport. Nat Cell Biol. 2014;16:1192-201 pubmed publisher
Abe T, Yamazaki D, Murakami S, Hiroi M, Nitta Y, Maeyama Y, et al. The NAV2 homolog Sickie regulates F-actin-mediated axonal growth in Drosophila mushroom body neurons via the non-canonical Rac-Cofilin pathway. Development. 2014;141:4716-28 pubmed publisher
Kang M, Jin H, Noh Y, Noh B. Repression of flowering under a noninductive photoperiod by the HDA9-AGL19-FT module in Arabidopsis. New Phytol. 2015;206:281-94 pubmed publisher
Martin L, Gardner L. Stress-induced inhibition of nonsense-mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11. Oncogene. 2015;34:4211-8 pubmed publisher
Mamoune A, Bahuau M, Hamel Y, Serre V, Pelosi M, Habarou F, et al. A thermolabile aldolase A mutant causes fever-induced recurrent rhabdomyolysis without hemolytic anemia. PLoS Genet. 2014;10:e1004711 pubmed publisher
Xiao Z, Sperl B, Ullrich A, Knyazev P. Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status. Oncotarget. 2014;5:12877-90 pubmed
Lu Y, Roy R. Centrosome/Cell cycle uncoupling and elimination in the endoreduplicating intestinal cells of C. elegans. PLoS ONE. 2014;9:e110958 pubmed publisher
Buisson N, Sirour C, Moreau N, Denker E, Le Bouffant R, Goullancourt A, et al. An adhesome comprising laminin, dystroglycan and myosin IIA is required during notochord development in Xenopus laevis. Development. 2014;141:4569-79 pubmed publisher
Xia P, Liu X, Wu B, Zhang S, Song X, Yao P, et al. Superresolution imaging reveals structural features of EB1 in microtubule plus-end tracking. Mol Biol Cell. 2014;25:4166-73 pubmed publisher
Kim T, Siesser P, Rossman K, Goldfarb D, Mackinnon K, Yan F, et al. Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase. Mol Cell Biol. 2015;35:167-81 pubmed publisher
Bauer M, Ahrné E, Baron A, Glatter T, Fava L, Santamaria A, et al. Evaluation of data-dependent and -independent mass spectrometric workflows for sensitive quantification of proteins and phosphorylation sites. J Proteome Res. 2014;13:5973-88 pubmed publisher
Yamagishi R, Wakayama T, Nakata H, Adthapanyawanich K, Kumchantuek T, Yamamoto M, et al. Expression and Localization of α-amylase in the Submandibular and Sublingual Glands of Mice. Acta Histochem Cytochem. 2014;47:95-102 pubmed publisher
Tegha Dunghu J, Bausch E, Neumann B, Wuensche A, Walter T, Ellenberg J, et al. MAP1S controls microtubule stability throughout the cell cycle in human cells. J Cell Sci. 2014;127:5007-13 pubmed publisher
Doi A, Ishikawa K, Shibata N, Ito E, Fujimoto J, Yamamoto M, et al. Enhanced expression of retinoic acid receptor alpha (RARA) induces epithelial-to-mesenchymal transition and disruption of mammary acinar structures. Mol Oncol. 2015;9:355-64 pubmed publisher
Wong Y, Holzbaur E. Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation. Proc Natl Acad Sci U S A. 2014;111:E4439-48 pubmed publisher
Gan C, Patel V, Mikelis C, Zain R, Molinolo A, Abraham M, et al. Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis. Oncotarget. 2014;5:9626-40 pubmed
Dimauro T, Cantor D, Bainor A, David G. Transcriptional repression of Sin3B by Bmi-1 prevents cellular senescence and is relieved by oncogene activation. Oncogene. 2015;34:4011-4017 pubmed publisher
Jackstadt R, Hermeking H. AP4 is required for mitogen- and c-MYC-induced cell cycle progression. Oncotarget. 2014;5:7316-27 pubmed
Lee S, Shea T. The high molecular weight neurofilament subunit plays an essential role in axonal outgrowth and stabilization. Biol Open. 2014;3:974-81 pubmed publisher
Kravtsov D, Mashukova A, Forteza R, Rodriguez M, Ameen N, SALAS P. Myosin 5b loss of function leads to defects in polarized signaling: implication for microvillus inclusion disease pathogenesis and treatment. Am J Physiol Gastrointest Liver Physiol. 2014;307:G992-G1001 pubmed publisher
Kong D, Farmer V, Shukla A, James J, Gruskin R, Kiriyama S, et al. Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles. J Cell Biol. 2014;206:855-65 pubmed publisher
Gallego Villar L, Viecelli H, Pérez B, Harding C, Ugarte M, Thöny B, et al. A sensitive assay system to test antisense oligonucleotides for splice suppression therapy in the mouse liver. Mol Ther Nucleic Acids. 2014;3:e193 pubmed publisher
Ray B, Chopra N, Long J, Lahiri D. Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research. Mol Brain. 2014;7:63 pubmed publisher
Gouarne C, Tracz J, Paoli M, DeLuca V, Seimandi M, Tardif G, et al. Protective role of olesoxime against wild-type α-synuclein-induced toxicity in human neuronally differentiated SHSY-5Y cells. Br J Pharmacol. 2015;172:235-45 pubmed publisher
Falk D, Todd A, Lee S, Soustek M, Elmallah M, Fuller D, et al. Peripheral nerve and neuromuscular junction pathology in Pompe disease. Hum Mol Genet. 2015;24:625-36 pubmed publisher
Trucco L, Andreoli V, Núñez N, Maccioni M, Bocco J. Krüppel-like factor 6 interferes with cellular transformation induced by the H-ras oncogene. FASEB J. 2014;28:5262-76 pubmed publisher
Zhang B, Mehrotra S, Ng W, Calvi B. Low levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells. PLoS Genet. 2014;10:e1004581 pubmed publisher
Meinke P, Mattioli E, Haque F, Antoku S, Columbaro M, Straatman K, et al. Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization. PLoS Genet. 2014;10:e1004605 pubmed publisher
Handke B, Szabad J, Lidsky P, Hafen E, Lehner C. Towards long term cultivation of Drosophila wing imaginal discs in vitro. PLoS ONE. 2014;9:e107333 pubmed publisher
Teichert I, Steffens E, Schnaß N, Fränzel B, Krisp C, Wolters D, et al. PRO40 is a scaffold protein of the cell wall integrity pathway, linking the MAP kinase module to the upstream activator protein kinase C. PLoS Genet. 2014;10:e1004582 pubmed publisher
Watanabe Susaki K, Takada H, Enomoto K, Miwata K, Ishimine H, Intoh A, et al. Biosynthesis of ribosomal RNA in nucleoli regulates pluripotency and differentiation ability of pluripotent stem cells. Stem Cells. 2014;32:3099-111 pubmed publisher
Lanaya H, Natarajan A, Komposch K, Li L, Amberg N, Chen L, et al. EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation. Nat Cell Biol. 2014;16:972-7 pubmed publisher
Zemp I, Lingner J. The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7. J Biol Chem. 2014;289:28595-606 pubmed publisher
Halstead J, Lin Y, Durraine L, Hamilton R, Ball G, Neely G, et al. Syncrip/hnRNP Q influences synaptic transmission and regulates BMP signaling at the Drosophila neuromuscular synapse. Biol Open. 2014;3:839-49 pubmed publisher
George C, Bozler J, Nguyen H, Bosco G. Condensins are Required for Maintenance of Nuclear Architecture. Cells. 2014;3:865-82 pubmed publisher
Mudhasani R, Kota K, Retterer C, Tran J, Whitehouse C, Bavari S. High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses. PLoS Negl Trop Dis. 2014;8:e3095 pubmed publisher
Dick G, Akslen Hoel L, Grøndahl F, Kjos I, Maccarana M, Prydz K. PAPST1 regulates sulfation of heparan sulfate proteoglycans in epithelial MDCK II cells. Glycobiology. 2015;25:30-41 pubmed publisher
Weaver I, Hellstrom I, Brown S, Andrews S, Dymov S, Diorio J, et al. The methylated-DNA binding protein MBD2 enhances NGFI-A (egr-1)-mediated transcriptional activation of the glucocorticoid receptor. Philos Trans R Soc Lond B Biol Sci. 2014;369: pubmed publisher
Annibali D, Whitfield J, Favuzzi E, Jauset T, Serrano E, Cuartas I, et al. Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis. Nat Commun. 2014;5:4632 pubmed publisher
Harz C, Ludwig N, Lang S, Werner T, Galata V, Backes C, et al. Secretion and immunogenicity of the meningioma-associated antigen TXNDC16. J Immunol. 2014;193:3146-54 pubmed publisher
Xu L, Hazard F, Zmoos A, Jahchan N, Chaib H, Garfin P, et al. Genomic analysis of fibrolamellar hepatocellular carcinoma. Hum Mol Genet. 2015;24:50-63 pubmed publisher
Chu L, Huo Y, Liu X, Yao P, Thomas K, Jiang H, et al. The spatiotemporal dynamics of chromatin protein HP1? is essential for accurate chromosome segregation during cell division. J Biol Chem. 2014;289:26249-62 pubmed publisher
Urban E, Nagarkar Jaiswal S, Lehner C, Heidmann S. The cohesin subunit Rad21 is required for synaptonemal complex maintenance, but not sister chromatid cohesion, during Drosophila female meiosis. PLoS Genet. 2014;10:e1004540 pubmed publisher
Nagai N, Kubota S, Tsubota K, Ozawa Y. Resveratrol prevents the development of choroidal neovascularization by modulating AMP-activated protein kinase in macrophages and other cell types. J Nutr Biochem. 2014;25:1218-1225 pubmed publisher
Choi Y, Saez B, Anders L, Hydbring P, Stefano J, Bacon N, et al. D-cyclins repress apoptosis in hematopoietic cells by controlling death receptor Fas and its ligand FasL. Dev Cell. 2014;30:255-67 pubmed publisher
Gomez Suaga P, Rivero Ríos P, Fdez E, Blanca Ramírez M, Ferrer I, Aiastui A, et al. LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity. Hum Mol Genet. 2014;23:6779-96 pubmed publisher
Iga M, Nakaoka T, Suzuki Y, Kataoka H. Pigment dispersing factor regulates ecdysone biosynthesis via bombyx neuropeptide G protein coupled receptor-B2 in the prothoracic glands of Bombyx mori. PLoS ONE. 2014;9:e103239 pubmed publisher
Choi P, Li Y, Felsher D. Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance. Proc Natl Acad Sci U S A. 2014;111:E3316-24 pubmed publisher
Amelio A, Fallahi M, Schaub F, Zhang M, Lawani M, Alperstein A, et al. CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement. Proc Natl Acad Sci U S A. 2014;111:E3260-8 pubmed publisher
Zhou L, Li Y, He W, Zhou D, Tan R, Nie J, et al. Mutual antagonism of Wilms' tumor 1 and ?-catenin dictates podocyte health and disease. J Am Soc Nephrol. 2015;26:677-91 pubmed publisher
Truscott M, Islam A, Lightfoot J, Lopez Bigas N, Frolov M. An intronic microRNA links Rb/E2F and EGFR signaling. PLoS Genet. 2014;10:e1004493 pubmed publisher
Ribeiro Varandas E, Ressurreição F, Viegas W, Delgado M. Cytotoxicity of Eupatorium cannabinum L. ethanolic extract against colon cancer cells and interactions with Bisphenol A and Doxorubicin. BMC Complement Altern Med. 2014;14:264 pubmed publisher
Saito K, Sakai C, Kawasaki T, Sakai N. Telomere distribution pattern and synapsis initiation during spermatogenesis in zebrafish. Dev Dyn. 2014;243:1448-56 pubmed publisher
Hirotsu Y, Higashi C, Fukutomi T, Katsuoka F, Tsujita T, Yagishita Y, et al. Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice. Genes Cells. 2014;19:650-65 pubmed publisher
Henard C, Carlsen E, Hay C, Kima P, Soong L. Leishmania amazonensis amastigotes highly express a tryparedoxin peroxidase isoform that increases parasite resistance to macrophage antimicrobial defenses and fosters parasite virulence. PLoS Negl Trop Dis. 2014;8:e3000 pubmed publisher
Hiradate Y, Inoue H, Kobayashi N, Shirakata Y, Suzuki Y, Gotoh A, et al. Neurotensin enhances sperm capacitation and acrosome reaction in mice. Biol Reprod. 2014;91:53 pubmed publisher
Zhang Y, Sicinska E, Czaplinski J, Remillard S, Moss S, Wang Y, et al. Antiproliferative effects of CDK4/6 inhibition in CDK4-amplified human liposarcoma in vitro and in vivo. Mol Cancer Ther. 2014;13:2184-93 pubmed publisher
Segatto I, Berton S, Sonego M, Massarut S, Perin T, Piccoli E, et al. Surgery-induced wound response promotes stem-like and tumor-initiating features of breast cancer cells, via STAT3 signaling. Oncotarget. 2014;5:6267-79 pubmed
Chauvigné F, Zapater C, Crespo D, Planas J, Cerdà J. Fsh and Lh direct conserved and specific pathways during flatfish semicystic spermatogenesis. J Mol Endocrinol. 2014;53:175-90 pubmed publisher
Simhadri S, Peterson S, Patel D, Huo Y, Cai H, Bowman Colin C, et al. Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice. J Biol Chem. 2014;289:24617-29 pubmed publisher
Su Y, Al Lamki R, Blake Palmer K, Best A, Golder Z, Zhou A, et al. Physical and functional links between anion exchanger-1 and sodium pump. J Am Soc Nephrol. 2015;26:400-9 pubmed publisher
Basilico F, Maffini S, Weir J, Prumbaum D, Rojas A, Zimniak T, et al. The pseudo GTPase CENP-M drives human kinetochore assembly. elife. 2014;3:e02978 pubmed publisher
Capaccione K, Hong X, Morgan K, Liu W, Bishop J, Liu L, et al. Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma. Oncotarget. 2014;5:3636-50 pubmed
Müller S, Montes De Oca R, Lacoste N, Dingli F, Loew D, Almouzni G. Phosphorylation and DNA binding of HJURP determine its centromeric recruitment and function in CenH3(CENP-A) loading. Cell Rep. 2014;8:190-203 pubmed publisher
Spracklen A, Fagan T, Lovander K, Tootle T. The pros and cons of common actin labeling tools for visualizing actin dynamics during Drosophila oogenesis. Dev Biol. 2014;393:209-226 pubmed publisher
Kushwaha D, Ramakrishnan V, Ng K, Steed T, Nguyen T, Futalan D, et al. A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas. Oncotarget. 2014;5:4026-39 pubmed
Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed publisher
Gatti L, Sevko A, De Cesare M, Arrighetti N, Manenti G, Ciusani E, et al. Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals. Oncotarget. 2014;5:4516-28 pubmed
Rakhshandehroo M, Gijzel S, Siersbæk R, Broekema M, de Haar C, Schipper H, et al. CD1d-mediated presentation of endogenous lipid antigens by adipocytes requires microsomal triglyceride transfer protein. J Biol Chem. 2014;289:22128-39 pubmed publisher
Smith C, Varoqueaux F, Kittelmann M, Azzam R, Cooper B, Winters C, et al. Novel cell types, neurosecretory cells, and body plan of the early-diverging metazoan Trichoplax adhaerens. Curr Biol. 2014;24:1565-1572 pubmed publisher
Lang A, Riherd Methner D, Ferreira A. Neuronal degeneration, synaptic defects, and behavioral abnormalities in tau?????? transgenic mice. Neuroscience. 2014;275:322-39 pubmed publisher
Veleri S, Manjunath S, Fariss R, May Simera H, Brooks M, Foskett T, et al. Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis. Nat Commun. 2014;5:4207 pubmed publisher
Trapp Fragnet L, Bencherit D, Chabanne Vautherot D, Le Vern Y, Remy S, Boutet Robinet E, et al. Cell cycle modulation by Marek's disease virus: the tegument protein VP22 triggers S-phase arrest and DNA damage in proliferating cells. PLoS ONE. 2014;9:e100004 pubmed publisher
Danielsen E, Moeller M, Dorry E, Komura Kawa T, Fujimoto Y, Troelsen J, et al. Transcriptional control of steroid biosynthesis genes in the Drosophila prothoracic gland by ventral veins lacking and knirps. PLoS Genet. 2014;10:e1004343 pubmed publisher
Vitre B, Gudimchuk N, Borda R, Kim Y, Heuser J, Cleveland D, et al. Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E. Mol Biol Cell. 2014;25:2272-81 pubmed publisher
De Marchi U, Santo Domingo J, Castelbou C, Sekler I, Wiederkehr A, Demaurex N. NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state. J Biol Chem. 2014;289:20377-85 pubmed publisher
Colciago A, Ruscica M, Mornati O, Piccolella M, Montagnani Marelli M, Eberini I, et al. In vitro chronic administration of ERbeta selective ligands and prostate cancer cell growth: hypotheses on the selective role of 3beta-adiol in AR-positive RV1 cells. Biomed Res Int. 2014;2014:801473 pubmed publisher
Allen M, Andrysik Z, Dengler V, Mellert H, Guarnieri A, Freeman J, et al. Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. elife. 2014;3:e02200 pubmed publisher
Torka R, Pénzes K, Gusenbauer S, Baumann C, Szabadkai I, Orfi L, et al. Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors: suggestion of combination therapy. Neoplasia. 2014;16:301-18 pubmed publisher
de Graaf E, Giansanti P, Altelaar A, Heck A. Single-step enrichment by Ti4+-IMAC and label-free quantitation enables in-depth monitoring of phosphorylation dynamics with high reproducibility and temporal resolution. Mol Cell Proteomics. 2014;13:2426-34 pubmed publisher
Hou N, Gutschmidt A, Choi D, Pather K, Shi X, Watts J, et al. Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo. Proc Natl Acad Sci U S A. 2014;111:E2271-80 pubmed publisher
Lepicard S, Franco B, de Bock F, Parmentier M. A presynaptic role of microtubule-associated protein 1/Futsch in Drosophila: regulation of active zone number and neurotransmitter release. J Neurosci. 2014;34:6759-71 pubmed publisher
Lee C. Transport of c-MYC by Kinesin-1 for proteasomal degradation in the cytoplasm. Biochim Biophys Acta. 2014;1843:2027-36 pubmed publisher
van Miltenburg M, van Nimwegen M, Tijdens I, Lalai R, Kuiper R, Klarenbeek S, et al. Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation. Br J Cancer. 2014;110:2747-55 pubmed publisher
Yasukawa S, Miyazaki Y, Yoshii C, Nakaya M, Ozaki N, Toda S, et al. An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells. Nat Commun. 2014;5:3755 pubmed publisher
Isono T, Chano T, Kitamura A, Yuasa T. Glucose deprivation induces G2/M transition-arrest and cell death in N-GlcNAc2-modified protein-producing renal carcinoma cells. PLoS ONE. 2014;9:e96168 pubmed publisher
Nam H, van Deursen J. Cyclin B2 and p53 control proper timing of centrosome separation. Nat Cell Biol. 2014;16:538-49 pubmed publisher
Komeno Y, Yan M, Matsuura S, Lam K, Lo M, Huang Y, et al. Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in mice. Blood. 2014;123:3760-9 pubmed publisher
Hussong M, Börno S, Kerick M, Wunderlich A, Franz A, Sultmann H, et al. The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. Cell Death Dis. 2014;5:e1195 pubmed publisher
Berger P, Frank S, Schulz V, Nollet E, Edick M, Holly B, et al. Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis. Cancer Res. 2014;74:3357-68 pubmed publisher
Laggai S, Kessler S, Boettcher S, Lebrun V, Gemperlein K, Lederer E, et al. The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis. J Lipid Res. 2014;55:1087-97 pubmed publisher
Láscarez Lagunas L, Silva García C, Dinkova T, Navarro R. LIN-35/Rb causes starvation-induced germ cell apoptosis via CED-9/Bcl2 downregulation in Caenorhabditis elegans. Mol Cell Biol. 2014;34:2499-516 pubmed publisher
Doughton G, Wei J, Tapon N, Welham M, Chalmers A. Formation of a polarised primitive endoderm layer in embryoid bodies requires fgfr/erk signalling. PLoS ONE. 2014;9:e95434 pubmed publisher
Lane A, Chapuy B, Lin C, Tivey T, Li H, Townsend E, et al. Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. Nat Genet. 2014;46:618-23 pubmed publisher
Hahn R, Hoppstädter J, Hirschfelder K, Hachenthal N, Diesel B, Kessler S, et al. Downregulation of the glucocorticoid-induced leucine zipper (GILZ) promotes vascular inflammation. Atherosclerosis. 2014;234:391-400 pubmed publisher
Zhou D, Li Y, Zhou L, Tan R, Xiao L, Liang M, et al. Sonic hedgehog is a novel tubule-derived growth factor for interstitial fibroblasts after kidney injury. J Am Soc Nephrol. 2014;25:2187-200 pubmed publisher
Siriwardana N, Meyer R, Havasi A, Dominguez I, Panchenko M. Cell cycle-dependent chromatin shuttling of HBO1-JADE1 histone acetyl transferase (HAT) complex. Cell Cycle. 2014;13:1885-901 pubmed publisher
Schaeffer V, Akutsu M, Olma M, Gomes L, Kawasaki M, Dikic I. Binding of OTULIN to the PUB domain of HOIP controls NF-?B signaling. Mol Cell. 2014;54:349-61 pubmed publisher
Banks C, Lee Z, Boanca G, Lakshminarasimhan M, Groppe B, Wen Z, et al. Controlling for gene expression changes in transcription factor protein networks. Mol Cell Proteomics. 2014;13:1510-22 pubmed publisher
Vazquez Pianzola P, Adam J, Haldemann D, Hain D, Urlaub H, Suter B. Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D. Development. 2014;141:1915-26 pubmed publisher
Weimer S, Priebs J, Kuhlow D, Groth M, Priebe S, Mansfeld J, et al. D-Glucosamine supplementation extends life span of nematodes and of ageing mice. Nat Commun. 2014;5:3563 pubmed publisher
He Z, Tian T, Guo D, Wu H, Chen Y, Zhang Y, et al. Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signaling. PLoS ONE. 2014;9:e94134 pubmed publisher
Schaller T, Pollpeter D, Apolonia L, Goujon C, Malim M. Nuclear import of SAMHD1 is mediated by a classical karyopherin ?/?1 dependent pathway and confers sensitivity to VpxMAC induced ubiquitination and proteasomal degradation. Retrovirology. 2014;11:29 pubmed publisher
Bentzinger C, von Maltzahn J, Dumont N, Stark D, Wang Y, Nhan K, et al. Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength. J Cell Biol. 2014;205:97-111 pubmed publisher
Kowno M, Watanabe Susaki K, Ishimine H, Komazaki S, Enomoto K, Seki Y, et al. Prohibitin 2 regulates the proliferation and lineage-specific differentiation of mouse embryonic stem cells in mitochondria. PLoS ONE. 2014;9:e81552 pubmed publisher
Ruppersburg C, Hartzell H. The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis. Mol Biol Cell. 2014;25:1793-807 pubmed publisher
Shahar O, Kalousi A, Eini L, Fisher B, Weiss A, Darr J, et al. A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair. Nucleic Acids Res. 2014;42:5689-701 pubmed publisher
Correa R, Krajewska M, Ware C, Gerlic M, Reed J. The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling. Oncotarget. 2014;5:1666-82 pubmed
Hergueta Redondo M, Sarrió D, Molina Crespo Ã, Megias D, Mota A, Rojo Sebastián A, et al. Gasdermin-B promotes invasion and metastasis in breast cancer cells. PLoS ONE. 2014;9:e90099 pubmed publisher
Grosse B, Degrouard J, Jaillard D, Cassio D. Build them up and break them down: Tight junctions of cell lines expressing typical hepatocyte polarity with a varied repertoire of claudins. Tissue Barriers. 2013;1:e25210 pubmed publisher
Contreras Vallejos E, Utreras E, Bórquez D, Prochazkova M, Terse A, Jaffe H, et al. Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice. PLoS ONE. 2014;9:e90363 pubmed publisher
Guan B, Krokowski D, Majumder M, Schmotzer C, Kimball S, Merrick W, et al. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2?. J Biol Chem. 2014;289:12593-611 pubmed publisher
Selvaraj N, Budka J, Ferris M, Jerde T, Hollenhorst P. Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation. Mol Cancer. 2014;13:61 pubmed publisher
Jo J, Hong S, Choi W, Lee D. Cell-penetrating peptide (CPP)-conjugated proteins is an efficient tool for manipulation of human mesenchymal stromal cells. Sci Rep. 2014;4:4378 pubmed publisher
Umashankar M, Rak M, Bughio F, Zagallo P, Caviness K, Goodrum F. Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection. J Virol. 2014;88:5987-6002 pubmed publisher
Green C, Day M. Insulin-like growth factor 1 acts as an autocrine factor to improve early embryogenesis in vitro. Int J Dev Biol. 2013;57:837-44 pubmed publisher
Münch S, Weidtkamp Peters S, Klement K, Grigaravicius P, Monajembashi S, Salomoni P, et al. The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence. Mol Cell Biol. 2014;34:1733-46 pubmed publisher
Almenar Queralt A, Falzone T, Shen Z, Lillo C, Killian R, Arreola A, et al. UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci. 2014;34:3320-39 pubmed publisher
Alvarez Quilón A, Serrano Benítez A, Lieberman J, Quintero C, Sánchez Gutiérrez D, Escudero L, et al. ATM specifically mediates repair of double-strand breaks with blocked DNA ends. Nat Commun. 2014;5:3347 pubmed publisher
Gritsman K, Yuzugullu H, Von T, Yan H, Clayton L, Fritsch C, et al. Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110?. J Clin Invest. 2014;124:1794-809 pubmed publisher
Yang Z, Nakagawa K, Sarkar A, Maruyama J, Iwasa H, Bao Y, et al. Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model. Mol Cell Biol. 2014;34:1607-21 pubmed publisher
Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, et al. Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy. Hum Mol Genet. 2014;23:3552-65 pubmed publisher
Gago Fuentes R, Carpintero Fernández P, Goldring M, Brink P, Mayan M, Blanco F. Biochemical evidence for gap junctions and Cx43 expression in immortalized human chondrocyte cell line: a potential model in the study of cell communication in human chondrocytes. Osteoarthritis Cartilage. 2014;22:586-90 pubmed publisher
Long L, Thelen J, Furgason M, Haj Yahya M, Brik A, Cheng D, et al. The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination. J Biol Chem. 2014;289:8916-30 pubmed publisher
Miyagi E, Kao S, Yedavalli V, Strebel K. CBF? enhances de novo protein biosynthesis of its binding partners HIV-1 Vif and RUNX1 and potentiates the Vif-induced degradation of APOBEC3G. J Virol. 2014;88:4839-52 pubmed publisher
Wang J, Liu X, Dou Z, Chen L, Jiang H, Fu C, et al. Mitotic regulator Mis18? interacts with and specifies the centromeric assembly of molecular chaperone holliday junction recognition protein (HJURP). J Biol Chem. 2014;289:8326-36 pubmed publisher
Yokoyama H, Koch B, Walczak R, Ciray Duygu F, González Sánchez J, Devos D, et al. The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation. Nat Commun. 2014;5:3270 pubmed publisher
Kakoi H, Maeda S, Shinohara N, Matsuyama K, Imamura K, Kawamura I, et al. Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanism. J Biol Chem. 2014;289:8135-50 pubmed publisher
He L, Marneros A. Doxycycline inhibits polarization of macrophages to the proangiogenic M2-type and subsequent neovascularization. J Biol Chem. 2014;289:8019-28 pubmed publisher
Fong J, Nimlamool W, Falk M. EGF induces efficient Cx43 gap junction endocytosis in mouse embryonic stem cell colonies via phosphorylation of Ser262, Ser279/282, and Ser368. FEBS Lett. 2014;588:836-44 pubmed publisher
Lu H, Lu Q, Gaddipati S, Kasetti R, Wang W, Pasparakis M, et al. IKK2 inhibition attenuates laser-induced choroidal neovascularization. PLoS ONE. 2014;9:e87530 pubmed publisher
Feraille E, Dizin E, Roth I, Derouette J, Szanto I, Martin P, et al. NADPH oxidase 4 deficiency reduces aquaporin-2 mRNA expression in cultured renal collecting duct principal cells via increased PDE3 and PDE4 activity. PLoS ONE. 2014;9:e87239 pubmed publisher
Feng W, Chang C, Luo D, Su H, Yu S, Hua W, et al. Dissection of autophagy in human platelets. Autophagy. 2014;10:642-51 pubmed publisher
Liu Z, Vong Q, Liu C, Zheng Y. Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells. Mol Biol Cell. 2014;25:841-51 pubmed publisher
Takenaka N, Izawa R, Wu J, Kitagawa K, Nihata Y, Hosooka T, et al. A critical role of the small GTPase Rac1 in Akt2-mediated GLUT4 translocation in mouse skeletal muscle. FEBS J. 2014;281:1493-504 pubmed publisher
Hosono Y, Abe T, Ishiai M, Islam M, Arakawa H, Wang W, et al. Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents. Biochim Biophys Acta. 2014;1843:1002-12 pubmed publisher
Matsuda Lennikov M, Suizu F, Hirata N, Hashimoto M, Kimura K, Nagamine T, et al. Lysosomal interaction of Akt with Phafin2: a critical step in the induction of autophagy. PLoS ONE. 2014;9:e79795 pubmed publisher
He Y, Kim H, Ryu T, Lee K, Choi W, Kim K, et al. C-Src-mediated phosphorylation of ?-catenin increases its protein stability and the ability of inducing nuclear distribution of ?-catenin. Biochim Biophys Acta. 2014;1843:758-68 pubmed publisher
Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, et al. Nrf2 enhances cholangiocyte expansion in Pten-deficient livers. Mol Cell Biol. 2014;34:900-13 pubmed publisher
Hibaoui Y, Grad I, Letourneau A, Sailani M, Dahoun S, Santoni F, et al. Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21. EMBO Mol Med. 2014;6:259-77 pubmed publisher
Jeong Y, Du R, Zhu X, Yin S, Wang J, Cui H, et al. Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1. J Leukoc Biol. 2014;95:651-9 pubmed publisher
Rafiei S, Komarova S. Molecular signaling pathways mediating osteoclastogenesis induced by prostate cancer cells. BMC Cancer. 2013;13:605 pubmed publisher
Shahbazi M, Megias D, Epifano C, Akhmanova A, Gundersen G, Fuchs E, et al. CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions. J Cell Biol. 2013;203:1043-61 pubmed publisher
Kopp F, Wagner E, Roidl A. The proto-oncogene KRAS is targeted by miR-200c. Oncotarget. 2014;5:185-95 pubmed
Khundadze M, Kollmann K, Koch N, Biskup C, Nietzsche S, Zimmer G, et al. A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system. PLoS Genet. 2013;9:e1003988 pubmed publisher
Rato L, Duarte A, Tomás G, Santos M, Moreira P, Socorro S, et al. Pre-diabetes alters testicular PGC1-?/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress. Biochim Biophys Acta. 2014;1837:335-44 pubmed publisher
Bin Nun N, Lichtig H, Malyarova A, Levy M, Elias S, Frank D. PTK7 modulates Wnt signaling activity via LRP6. Development. 2014;141:410-21 pubmed publisher
Folker E, Schulman V, Baylies M. Translocating myonuclei have distinct leading and lagging edges that require kinesin and dynein. Development. 2014;141:355-66 pubmed publisher
Jeanplong F, Falconer S, Oldham J, Thomas M, Gray T, Hennebry A, et al. Discovery of a mammalian splice variant of myostatin that stimulates myogenesis. PLoS ONE. 2013;8:e81713 pubmed publisher
Delic S, Lottmann N, Stelzl A, Liesenberg F, Wolter M, Götze S, et al. MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation. Neuro Oncol. 2014;16:179-90 pubmed publisher
Spracklen A, Kelpsch D, Chen X, Spracklen C, Tootle T. Prostaglandins temporally regulate cytoplasmic actin bundle formation during Drosophila oogenesis. Mol Biol Cell. 2014;25:397-411 pubmed publisher
Hammond S, Byrum S, Namjoshi S, Graves H, Dennehey B, Tackett A, et al. Mitotic phosphorylation of histone H3 threonine 80. Cell Cycle. 2014;13:440-52 pubmed publisher
Grolimund L, Aeby E, Hamelin R, Armand F, Chiappe D, Moniatte M, et al. A quantitative telomeric chromatin isolation protocol identifies different telomeric states. Nat Commun. 2013;4:2848 pubmed publisher
Tan R, Zhou L, Zhou D, Lin L, Liu Y. Endothelin receptor a blockade is an ineffective treatment for adriamycin nephropathy. PLoS ONE. 2013;8:e79963 pubmed publisher
Subtil Rodríguez A, Vázquez Chávez E, Ceballos Chávez M, Rodríguez Paredes M, Martin Subero J, Esteller M, et al. The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes. Nucleic Acids Res. 2014;42:2185-96 pubmed publisher
Shi H, Hugo W, Kong X, Hong A, Koya R, Moriceau G, et al. Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy. Cancer Discov. 2014;4:80-93 pubmed publisher
Kovacevic Grujicic N, Mojsin M, Popovic J, Petrovic I, Topalovic V, Stevanovic M. Cyclic AMP response element binding (CREB) protein acts as a positive regulator of SOX3 gene expression in NT2/D1 cells. BMB Rep. 2014;47:197-202 pubmed
Ishii Y, Nakahara T, Kataoka M, Kusumoto Matsuo R, Mori S, Takeuchi T, et al. Identification of TRAPPC8 as a host factor required for human papillomavirus cell entry. PLoS ONE. 2013;8:e80297 pubmed publisher
Zhang S, Li J, Lea R, Amaya E, Dorey K. A functional genome-wide in vivo screen identifies new regulators of signalling pathways during early Xenopus embryogenesis. PLoS ONE. 2013;8:e79469 pubmed publisher
Zheng L, Sepúlveda L, Lua R, Lichtarge O, Golding I, Sokac A. The maternal-to-zygotic transition targets actin to promote robustness during morphogenesis. PLoS Genet. 2013;9:e1003901 pubmed publisher
Millanes Romero A, Herranz N, Perrera V, Iturbide A, Loubat Casanovas J, Gil J, et al. Regulation of heterochromatin transcription by Snail1/LOXL2 during epithelial-to-mesenchymal transition. Mol Cell. 2013;52:746-57 pubmed publisher
Farag H, Froehler S, Oexle K, Ravindran E, Schindler D, Staab T, et al. Abnormal centrosome and spindle morphology in a patient with autosomal recessive primary microcephaly type 2 due to compound heterozygous WDR62 gene mutation. Orphanet J Rare Dis. 2013;8:178 pubmed publisher
Welcker J, Hernández Miranda L, Paul F, Jia S, Ivanov A, Selbach M, et al. Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors. Development. 2013;140:4947-58 pubmed publisher
Han Y, Park S, Kinyua A, Andera L, Kim K, Kim I. Emetine enhances the tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of pancreatic cancer cells by downregulation of myeloid cell leukemia sequence-1 protein. Oncol Rep. 2014;31:456-62 pubmed publisher
Kuo P, Chiang H, Wang Y, Kuo Y, Chen M, Yu I, et al. SEPT12-microtubule complexes are required for sperm head and tail formation. Int J Mol Sci. 2013;14:22102-16 pubmed publisher
Barnhart M, Moon S, Emch A, Wilusz C, Wilusz J. Changes in cellular mRNA stability, splicing, and polyadenylation through HuR protein sequestration by a cytoplasmic RNA virus. Cell Rep. 2013;5:909-17 pubmed publisher
Watts C, Richards F, Bender A, Bond P, Korb O, Kern O, et al. Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes. Chem Biol. 2013;20:1399-410 pubmed publisher
Feldstein O, Nizri T, Doniger T, Jacob J, Rechavi G, Ginsberg D. The long non-coding RNA ERIC is regulated by E2F and modulates the cellular response to DNA damage. Mol Cancer. 2013;12:131 pubmed publisher
Tattoli I, Sorbara M, Yang C, Tooze S, Philpott D, Girardin S. Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures. EMBO J. 2013;32:3066-78 pubmed publisher
Viñas Castells R, Frias A, Robles Lanuza E, Zhang K, Longmore G, Garcia de Herreros A, et al. Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability. Nucleic Acids Res. 2014;42:1079-94 pubmed publisher
Maejima Y, Kyoi S, Zhai P, Liu T, Li H, Ivessa A, et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med. 2013;19:1478-88 pubmed publisher
Gao Y, Koppen A, Rakhshandehroo M, Taşdelen I, van de Graaf S, van Loosdregt J, et al. Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60. Nat Commun. 2013;4:2656 pubmed publisher
Shimizu T, Fukumoto Y, Tanaka S, Satoh K, Ikeda S, Shimokawa H. Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice. Arterioscler Thromb Vasc Biol. 2013;33:2780-91 pubmed publisher
de Groot R, Farin H, Macůrková M, van Es J, Clevers H, Korswagen H. Retromer dependent recycling of the Wnt secretion factor Wls is dispensable for stem cell maintenance in the mammalian intestinal epithelium. PLoS ONE. 2013;8:e76971 pubmed publisher
Mendel I, Feige E, Yacov N, Salem Y, Levi I, Propheta Meiran O, et al. VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis. Clin Exp Immunol. 2014;175:126-37 pubmed publisher
Pereira L, Igea A, Canovas B, Dolado I, Nebreda A. Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. EMBO Mol Med. 2013;5:1759-74 pubmed publisher
Yamamoto K, Tsuzuki S, Minami Y, Yamamoto Y, Abe A, Ohshima K, et al. Functionally deregulated AML1/RUNX1 cooperates with BCR-ABL to induce a blastic phase-like phenotype of chronic myelogenous leukemia in mice. PLoS ONE. 2013;8:e74864 pubmed publisher
Baron D, Kaushansky L, Ward C, Sama R, Chian R, Boggio K, et al. Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics. Mol Neurodegener. 2013;8:30 pubmed publisher
Kroon J, Tol S, van Amstel S, Elias J, Fernandez Borja M. The small GTPase RhoB regulates TNF? signaling in endothelial cells. PLoS ONE. 2013;8:e75031 pubmed publisher
Xue J, Woo E, Postow L, Chait B, Funabiki H. Chromatin-bound Xenopus Dppa2 shapes the nucleus by locally inhibiting microtubule assembly. Dev Cell. 2013;27:47-59 pubmed publisher
Hofmann J, Tegha Dunghu J, Dräger S, Will C, Luhrmann R, Gruss O. The Prp19 complex directly functions in mitotic spindle assembly. PLoS ONE. 2013;8:e74851 pubmed publisher
Suzuki S, Nozawa Y, Tsukamoto S, Kaneko T, Imai H, Minami N. ING3 is essential for asymmetric cell division during mouse oocyte maturation. PLoS ONE. 2013;8:e74749 pubmed publisher
Lu C, Venneti S, Akalin A, Fang F, Ward P, Dematteo R, et al. Induction of sarcomas by mutant IDH2. Genes Dev. 2013;27:1986-98 pubmed publisher
Chen C, Liu Y, Lu C, Cross J, Morris J, Shroff A, et al. Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition. Genes Dev. 2013;27:1974-85 pubmed publisher
Nishimura T, Uchida Y, Yachi R, Kudlyk T, Lupashin V, Inoue T, et al. Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs. Mol Biol Cell. 2013;24:3534-44 pubmed publisher
Venables J, Lapasset L, Gadea G, Fort P, Klinck R, Irimia M, et al. MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation. Nat Commun. 2013;4:2480 pubmed publisher
Harris J, Richards R, Chow C, Lee S, Kim M, Buck M, et al. BMCC1 is an AP-2 associated endosomal protein in prostate cancer cells. PLoS ONE. 2013;8:e73880 pubmed publisher
Yuan H, Russell R, Guan K. Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy. 2013;9:1983-95 pubmed
Kabeche L, Compton D. Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation. Nature. 2013;502:110-3 pubmed publisher
Iwasa H, Kudo T, Maimaiti S, Ikeda M, Maruyama J, Nakagawa K, et al. The RASSF6 tumor suppressor protein regulates apoptosis and the cell cycle via MDM2 protein and p53 protein. J Biol Chem. 2013;288:30320-9 pubmed publisher
Lawrence E, Mandato C. Mitochondria localize to the cleavage furrow in mammalian cytokinesis. PLoS ONE. 2013;8:e72886 pubmed publisher
Danson C, Brown E, Hemmings O, McGough I, Yarwood S, Heesom K, et al. SNX15 links clathrin endocytosis to the PtdIns3P early endosome independently of the APPL1 endosome. J Cell Sci. 2013;126:4885-99 pubmed publisher
Nakaya Y, Sukowati E, Sheng G. Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex. J Cell Biol. 2013;202:637-51 pubmed publisher
Mavroconstanti T, Johansson S, Winge I, Knappskog P, Haavik J. Functional properties of rare missense variants of human CDH13 found in adult attention deficit/hyperactivity disorder (ADHD) patients. PLoS ONE. 2013;8:e71445 pubmed publisher
Redon S, Zemp I, Lingner J. A three-state model for the regulation of telomerase by TERRA and hnRNPA1. Nucleic Acids Res. 2013;41:9117-28 pubmed publisher
Papacleovoulou G, Abu Hayyeh S, Nikolopoulou E, Briz O, Owen B, Nikolova V, et al. Maternal cholestasis during pregnancy programs metabolic disease in offspring. J Clin Invest. 2013;123:3172-81 pubmed publisher
Akef A, Zhang H, Masuda S, Palazzo A. Trafficking of mRNAs containing ALREX-promoting elements through nuclear speckles. Nucleus. 2013;4:326-40 pubmed publisher
Dubas E, Custers J, Kieft H, Wedzony M, Van Lammeren A. Characterization of polarity development through 2- and 3-D imaging during the initial phase of microspore embryogenesis in Brassica napus L. Protoplasma. 2014;251:103-13 pubmed publisher
Moser S, Bensaddek D, Ortmann B, Maure J, Mudie S, Blow J, et al. PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192. Dev Cell. 2013;26:381-92 pubmed publisher
Viiri J, Amadio M, Marchesi N, Hyttinen J, Kivinen N, Sironen R, et al. Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells. PLoS ONE. 2013;8:e69563 pubmed publisher
Jene Sanz A, Váraljai R, Vilkova A, Khramtsova G, Khramtsov A, Olopade O, et al. Expression of polycomb targets predicts breast cancer prognosis. Mol Cell Biol. 2013;33:3951-61 pubmed publisher
Bacman S, Williams S, Pinto M, Peralta S, Moraes C. Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs. Nat Med. 2013;19:1111-3 pubmed publisher
Schlaitz A, Thompson J, Wong C, Yates J, Heald R. REEP3/4 ensure endoplasmic reticulum clearance from metaphase chromatin and proper nuclear envelope architecture. Dev Cell. 2013;26:315-23 pubmed publisher
Kullmann M, Grubbauer C, Goetsch K, Jakel H, Podmirseg S, Trockenbacher A, et al. The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells. Cell Cycle. 2013;12:2625-35 pubmed publisher
Chan K, Han J, Fang D, Gan H, Zhang Z. A lesson learned from the H3.3K27M mutation found in pediatric glioma: a new approach to the study of the function of histone modifications in vivo?. Cell Cycle. 2013;12:2546-52 pubmed publisher
McElwee M, Beilstein F, Labetoulle M, Rixon F, Pasdeloup D. Dystonin/BPAG1 promotes plus-end-directed transport of herpes simplex virus 1 capsids on microtubules during entry. J Virol. 2013;87:11008-18 pubmed publisher
Fong J, Kells R, Falk M. Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis. Mol Biol Cell. 2013;24:2834-48 pubmed publisher
Dizin E, Hasler U, Nlandu Khodo S, Fila M, Roth I, Ernandez T, et al. Albuminuria induces a proinflammatory and profibrotic response in cortical collecting ducts via the 24p3 receptor. Am J Physiol Renal Physiol. 2013;305:F1053-63 pubmed publisher
Gnatovskiy L, Mita P, Levy D. The human RVB complex is required for efficient transcription of type I interferon-stimulated genes. Mol Cell Biol. 2013;33:3817-25 pubmed publisher
Koren L, Elhanani O, Kehat I, Hai T, Aronheim A. Adult cardiac expression of the activating transcription factor 3, ATF3, promotes ventricular hypertrophy. PLoS ONE. 2013;8:e68396 pubmed publisher
Strutt H, Thomas MacArthur V, Strutt D. Strabismus promotes recruitment and degradation of farnesylated prickle in Drosophila melanogaster planar polarity specification. PLoS Genet. 2013;9:e1003654 pubmed publisher
Frühbeis C, Fröhlich D, Kuo W, Amphornrat J, Thilemann S, Saab A, et al. Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol. 2013;11:e1001604 pubmed publisher
Huang F, Wang X, Ostertag E, Nuwal T, Huang B, Jan Y, et al. TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Nat Neurosci. 2013;16:1284-90 pubmed publisher
Sáez de Guinoa J, Barrio L, Carrasco Y. Vinculin arrests motile B cells by stabilizing integrin clustering at the immune synapse. J Immunol. 2013;191:2742-51 pubmed publisher
Sapir T, Levy T, Sakakibara A, Rabinkov A, Miyata T, Reiner O. Shootin1 acts in concert with KIF20B to promote polarization of migrating neurons. J Neurosci. 2013;33:11932-48 pubmed publisher
Ordureau A, Enesa K, Nanda S, Le François B, Peggie M, Prescott A, et al. DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA. J Biol Chem. 2013;288:24569-80 pubmed publisher
Schulman V, Folker E, Baylies M. A method for reversible drug delivery to internal tissues of Drosophila embryos. Fly (Austin). 2013;7:193-203 pubmed publisher
Nesca V, Guay C, Jacovetti C, Menoud V, Peyot M, Laybutt D, et al. Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes. Diabetologia. 2013;56:2203-12 pubmed publisher
Duncan J, Lytle N, Zuniga A, Goldstein L. The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS ONE. 2013;8:e68324 pubmed publisher
Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, et al. Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells. Endocr Relat Cancer. 2013;20:633-47 pubmed publisher
B renz F, Inoue D, Yokoyama H, Tegha Dunghu J, Freiss S, Draeger S, et al. The centriolar satellite protein SSX2IP promotes centrosome maturation. J Cell Biol. 2013;202:81-95 pubmed publisher
Pietiäinen V, Vassilev B, Blom T, Wang W, Nelson J, Bittman R, et al. NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation. J Cell Sci. 2013;126:3961-71 pubmed publisher
Tabler J, Barrell W, Szabo Rogers H, Healy C, Yeung Y, Perdiguero E, et al. Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Dev Cell. 2013;25:623-35 pubmed publisher
Tönjes M, Barbus S, Park Y, Wang W, Schlotter M, Lindroth A, et al. BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1. Nat Med. 2013;19:901-908 pubmed publisher
Jones C, Grima D, Waldron J, Jones S, Parker H, Newbury S. The 5'-3' exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277-3p in Drosophila wing imaginal discs. RNA Biol. 2013;10:1345-55 pubmed publisher
Ambjørn M, Dubreuil V, Miozzo F, Nigon F, Møller B, Issazadeh Navikas S, et al. A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation. PLoS ONE. 2013;8:e65371 pubmed publisher
Maruzuru Y, Fujii H, Oyama M, Kozuka Hata H, Kato A, Kawaguchi Y. Roles of p53 in herpes simplex virus 1 replication. J Virol. 2013;87:9323-32 pubmed publisher
Salvado M, Di Gennaro A, Lindbom L, Agerberth B, Haeggstrom J. Cathelicidin LL-37 induces angiogenesis via PGE2-EP3 signaling in endothelial cells, in vivo inhibition by aspirin. Arterioscler Thromb Vasc Biol. 2013;33:1965-72 pubmed publisher
de la Cueva A, Ramirez de Molina A, Alvarez Ayerza N, Ramos M, Cebrian A, del Pulgar T, et al. Combined 5-FU and ChoK? inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts. PLoS ONE. 2013;8:e64961 pubmed publisher
Fradet Turcotte A, Canny M, Escribano Diaz C, Orthwein A, Leung C, Huang H, et al. 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark. Nature. 2013;499:50-4 pubmed publisher
Agra N, Cidre F, García García L, de la Parra J, Alonso J. Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells. PLoS ONE. 2013;8:e66281 pubmed publisher
Naito T, Kuma A, Mizushima N. Differential contribution of insulin and amino acids to the mTORC1-autophagy pathway in the liver and muscle. J Biol Chem. 2013;288:21074-81 pubmed publisher
Sampson J, Duston J, Croll R. Superficial neuromasts facilitate non-visual feeding by larval striped bass (Morone saxatilis). J Exp Biol. 2013;216:3522-30 pubmed publisher
Maddala R, Nagendran T, de Ridder G, Schey K, Rao P. L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins. PLoS ONE. 2013;8:e64676 pubmed publisher
Courjaret R, Hubrack S, Daalis A, Dib M, Machaca K. The Xenopus TRPV6 homolog encodes a Mg(2+) -permeant channel that is inhibited by interaction with TRPC1. J Cell Physiol. 2013;228:2386-98 pubmed publisher
Ahmed S, Wittenmayer N, Kremer T, Hoeber J, Kiran Akula A, Urlaub H, et al. Mover is a homomeric phospho-protein present on synaptic vesicles. PLoS ONE. 2013;8:e63474 pubmed publisher
Neguembor M, Xynos A, Onorati M, Caccia R, Bortolanza S, Godio C, et al. FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis. J Mol Cell Biol. 2013;5:294-307 pubmed publisher
Motizuki M, Isogaya K, Miyake K, Ikushima H, Kubota T, Miyazono K, et al. Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-?. J Biol Chem. 2013;288:18911-22 pubmed publisher
Hernández G, Miron M, Han H, Liu N, Magescas J, Tettweiler G, et al. Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster. Mol Cell Biol. 2013;33:2854-64 pubmed publisher
Rivkin E, Almeida S, Ceccarelli D, Juang Y, MacLean T, Srikumar T, et al. The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature. 2013;498:318-24 pubmed publisher
Guijarro M, Dahiya S, Danielson L, Segura M, Vales Lara F, Menendez S, et al. Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling. Am J Pathol. 2013;182:2015-27 pubmed publisher
Pacurari M, Addison J, Bondalapati N, Wan Y, Luo D, Qian Y, et al. The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells. Int J Oncol. 2013;43:548-60 pubmed publisher
Sporbert A, Cseresnyes Z, Heidbreder M, Domaing P, Hauser S, Kaltschmidt B, et al. Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots. PLoS ONE. 2013;8:e64023 pubmed publisher
Zhou D, Tan R, Zhou L, Li Y, Liu Y. Kidney tubular ?-catenin signaling controls interstitial fibroblast fate via epithelial-mesenchymal communication. Sci Rep. 2013;3:1878 pubmed publisher
Siegert P, Schmidt G, Papatheodorou P, Wieland T, Aktories K, Orth J. Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the G?(q/11)--p63RhoGEF--RhoA axis. PLoS Pathog. 2013;9:e1003385 pubmed publisher
Heng M, Lin S, Verret L, Huang Y, Kamiya S, Padiath Q, et al. Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model. J Clin Invest. 2013;123:2719-29 pubmed publisher
Woods K, Theiler R, Mühlemann M, Segiser A, Huber S, Ansari H, et al. Recruitment of EB1, a master regulator of microtubule dynamics, to the surface of the Theileria annulata schizont. PLoS Pathog. 2013;9:e1003346 pubmed publisher
Childs K, Randall R, Goodbourn S. LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA. PLoS ONE. 2013;8:e64202 pubmed publisher
Garfin P, Min D, Bryson J, Serwold T, Edris B, Blackburn C, et al. Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. J Exp Med. 2013;210:1087-97 pubmed publisher
Shaposhnikov D, Kuffer C, Storchova Z, Posern G. Myocardin related transcription factors are required for coordinated cell cycle progression. Cell Cycle. 2013;12:1762-72 pubmed publisher
Wang W, Tay H, Soni R, Perumal G, Goll M, Macaluso F, et al. CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base. Nat Cell Biol. 2013;15:591-601 pubmed publisher
Marsolier J, Pineau S, Medjkane S, Perichon M, Yin Q, Flemington E, et al. OncomiR addiction is generated by a miR-155 feedback loop in Theileria-transformed leukocytes. PLoS Pathog. 2013;9:e1003222 pubmed publisher
Hilgendorf K, Leshchiner E, Nedelcu S, Maynard M, Calo E, Ianari A, et al. The retinoblastoma protein induces apoptosis directly at the mitochondria. Genes Dev. 2013;27:1003-15 pubmed publisher
Fong J, Le Nihouannen D, Tiedemann K, Sadvakassova G, Barralet J, Komarova S. Moderate excess of pyruvate augments osteoclastogenesis. Biol Open. 2013;2:387-95 pubmed publisher
Correia S, Oliveira P, Guerreiro P, Lopes G, Alves M, Canario A, et al. Sperm parameters and epididymis function in transgenic rats overexpressing the Ca2+-binding protein regucalcin: a hidden role for Ca2+ in sperm maturation?. Mol Hum Reprod. 2013;19:581-9 pubmed publisher
Elfert S, Weise A, Bruser K, Biniossek M, Jägle S, Senghaas N, et al. Acetylation of human TCF4 (TCF7L2) proteins attenuates inhibition by the HBP1 repressor and induces a conformational change in the TCF4::DNA complex. PLoS ONE. 2013;8:e61867 pubmed publisher
Rajala H, Eldfors S, Kuusanmäki H, van Adrichem A, Olson T, Lagström S, et al. Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia. Blood. 2013;121:4541-50 pubmed publisher
Yu X, Muñoz Alarcón A, Ajayi A, Webling K, Steinhof A, Langel U, et al. Inhibition of autophagy via p53-mediated disruption of ULK1 in a SCA7 polyglutamine disease model. J Mol Neurosci. 2013;50:586-99 pubmed publisher
Issa L, Mueller K, Seufert K, Kraemer N, Rosenkotter H, Ninnemann O, et al. Clinical and cellular features in patients with primary autosomal recessive microcephaly and a novel CDK5RAP2 mutation. Orphanet J Rare Dis. 2013;8:59 pubmed publisher
Anantha R, Alcivar A, Ma J, Cai H, Simhadri S, Ule J, et al. Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination. PLoS ONE. 2013;8:e61368 pubmed publisher
Wong H, Veremeyko T, Patel N, Lemere C, Walsh D, Esau C, et al. De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease. Hum Mol Genet. 2013;22:3077-92 pubmed publisher
Lazzeroni G, Benicchi T, Heitz F, Magnoni L, Diamanti D, Rossini L, et al. A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation. J Biomol Screen. 2013;18:984-96 pubmed publisher
Isono T, Chano T, Okabe H, Suzaki M. Study of global transcriptional changes of N-GlcNAc2 proteins-producing T24 bladder carcinoma cells under glucose deprivation. PLoS ONE. 2013;8:e60397 pubmed publisher
Amato F, Seia M, Giordano S, Elce A, Zarrilli F, Castaldo G, et al. Gene mutation in microRNA target sites of CFTR gene: a novel pathogenetic mechanism in cystic fibrosis?. PLoS ONE. 2013;8:e60448 pubmed publisher
Jung H, Patel R, Phillips B, Wang H, Cohen D, Reinhold W, et al. Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions. Mol Biol Cell. 2013;24:1638-48, S1-7 pubmed publisher
Suswam E, Shacka J, Walker K, Lu L, Li X, Si Y, et al. Mutant tristetraprolin: a potent inhibitor of malignant glioma cell growth. J Neurooncol. 2013;113:195-205 pubmed publisher
Bogdanik L, Sleigh J, Tian C, Samuels M, Bedard K, Seburn K, et al. Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease. Dis Model Mech. 2013;6:780-92 pubmed publisher
Pfaff K, King R. Determinants of human cyclin B1 association with mitotic chromosomes. PLoS ONE. 2013;8:e59169 pubmed publisher
Veloso A, Chow A, Dhar D, Tang D, Ganesh H, Mikhaylichenko S, et al. Biological activity of sym-triazines with acetylcholine-like substitutions as multitarget modulators of Alzheimer's disease. ACS Chem Neurosci. 2013;4:924-9 pubmed publisher
Warsch W, Grundschober E, Berger A, Gille L, Cerny Reiterer S, Tigan A, et al. STAT5 triggers BCR-ABL1 mutation by mediating ROS production in chronic myeloid leukaemia. Oncotarget. 2012;3:1669-87 pubmed
Yeh T, Kowalska A, Scipioni B, Cheong F, Zheng M, Derewenda U, et al. Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit. EMBO J. 2013;32:1023-35 pubmed publisher
Yehezkel S, Shaked R, Sagie S, Berkovitz R, Shachar Bener H, Segev Y, et al. Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts. Front Oncol. 2013;3:35 pubmed publisher
Ngan E, Northey J, Brown C, Ursini Siegel J, Siegel P. A complex containing LPP and ?-actinin mediates TGF?-induced migration and invasion of ErbB2-expressing breast cancer cells. J Cell Sci. 2013;126:1981-91 pubmed publisher
Tsubouchi T, Soza Ried J, Brown K, Piccolo F, Cantone I, Landeira D, et al. DNA synthesis is required for reprogramming mediated by stem cell fusion. Cell. 2013;152:873-83 pubmed publisher
Vernerey J, Macchi M, Magalon K, Cayre M, Durbec P. Ciliary neurotrophic factor controls progenitor migration during remyelination in the adult rodent brain. J Neurosci. 2013;33:3240-50 pubmed publisher
Ono T, Yamashita D, Hirano T. Condensin II initiates sister chromatid resolution during S phase. J Cell Biol. 2013;200:429-41 pubmed publisher
Nunes P, Ernandez T, Roth I, Qiao X, Strebel D, Bouley R, et al. Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters. Autophagy. 2013;9:550-67 pubmed publisher
Skamagki M, Wicher K, Jedrusik A, Ganguly S, Zernicka Goetz M. Asymmetric localization of Cdx2 mRNA during the first cell-fate decision in early mouse development. Cell Rep. 2013;3:442-57 pubmed publisher
Malavaki C, Roussidis A, Gialeli C, Kletsas D, Tsegenidis T, Theocharis A, et al. Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells. FEBS J. 2013;280:2477-89 pubmed publisher
Zhou K, Rolls M, Hanna Rose W. A postmitotic function and distinct localization mechanism for centralspindlin at a stable intercellular bridge. Dev Biol. 2013;376:13-22 pubmed publisher
Suga H, Ruiz Trillo I. Development of ichthyosporeans sheds light on the origin of metazoan multicellularity. Dev Biol. 2013;377:284-92 pubmed publisher
José A, Sobrevals L, Miguel Camacho Sánchez J, Huch M, Andreu N, Ayuso E, et al. Intraductal delivery of adenoviruses targets pancreatic tumors in transgenic Ela-myc mice and orthotopic xenografts. Oncotarget. 2013;4:94-105 pubmed
Janssens E, Gaublomme D, De Groef L, Darras V, Arckens L, Delorme N, et al. Matrix metalloproteinase 14 in the zebrafish: an eye on retinal and retinotectal development. PLoS ONE. 2013;8:e52915 pubmed publisher
Ahn E, Higashi T, Yan M, Matsuura S, Hickey C, Lo M, et al. SON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 cluster. J Biol Chem. 2013;288:5381-8 pubmed publisher
Auclair S, Uzbekov R, Elis S, Sanchez L, Kireev I, Lardic L, et al. Absence of cumulus cells during in vitro maturation affects lipid metabolism in bovine oocytes. Am J Physiol Endocrinol Metab. 2013;304:E599-613 pubmed publisher
Silva G, Cardoso B, Belo H, Almeida A. Vorinostat induces apoptosis and differentiation in myeloid malignancies: genetic and molecular mechanisms. PLoS ONE. 2013;8:e53766 pubmed publisher
Ranzani M, Cesana D, Bartholomae C, Sanvito F, Pala M, Benedicenti F, et al. Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer. Nat Methods. 2013;10:155-61 pubmed publisher
Chong R, Gonzalez Gonzalez E, Lara M, Speaker T, Contag C, Kaspar R, et al. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. J Control Release. 2013;166:211-9 pubmed publisher
Hussain S, Feldman A, Das C, Ziesmer S, Ansell S, Galardy P. Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor. Mol Cell Biol. 2013;33:1188-97 pubmed publisher
González Gugel E, Villa Morales M, Santos J, Bueno M, Malumbres M, Rodriguez Pinilla S, et al. Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development. Carcinogenesis. 2013;34:902-8 pubmed publisher
Soria G, Almouzni G. Differential contribution of HP1 proteins to DNA end resection and homology-directed repair. Cell Cycle. 2013;12:422-9 pubmed publisher
Scheer J, Sandoval W, Elliott J, Shao L, Luis E, Lewin Koh S, et al. Reorienting the Fab domains of trastuzumab results in potent HER2 activators. PLoS ONE. 2012;7:e51817 pubmed publisher
Coronnello C, Hartmaier R, Arora A, Huleihel L, Pandit K, Bais A, et al. Novel modeling of combinatorial miRNA targeting identifies SNP with potential role in bone density. PLoS Comput Biol. 2012;8:e1002830 pubmed publisher
Northey J, Dong Z, Ngan E, Kaplan A, Hardy W, Pawson T, et al. Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor ? (TGF?)-induced breast cancer cell migration, invasion, and metastasis. J Biol Chem. 2013;288:5210-22 pubmed publisher
Wehr M, Holder M, Gailite I, Saunders R, Maile T, Ciirdaeva E, et al. Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila. Nat Cell Biol. 2013;15:61-71 pubmed
Wang F, Sarmasik A, Hiruma Y, Sun Q, Sammut B, Windle J, et al. Measles virus nucleocapsid protein, a key contributor to Paget's disease, increases IL-6 expression via down-regulation of FoxO3/Sirt1 signaling. Bone. 2013;53:269-76 pubmed publisher
Jia S, Gao X, Lee S, Maira S, Wu X, Stack E, et al. Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention. Cancer Discov. 2013;3:44-51 pubmed publisher
Han J, Hubbard B, Lee J, Montagna C, Lee H, Sinclair D, et al. Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene. Cell Cycle. 2013;12:263-70 pubmed publisher
Cavallo F, Graziani G, Antinozzi C, Feldman D, Houldsworth J, Bosl G, et al. Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition. PLoS ONE. 2012;7:e51563 pubmed publisher
Baker D, Dawlaty M, Wijshake T, Jeganathan K, Malureanu L, van Ree J, et al. Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan. Nat Cell Biol. 2013;15:96-102 pubmed publisher
Rannikko E, Vesterager L, Shaik J, Weber S, Cornejo Castro E, Fog K, et al. Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion. J Neurochem. 2013;125:314-27 pubmed publisher
Delepine C, Nectoux J, Bahi Buisson N, Chelly J, Bienvenu T. MeCP2 deficiency is associated with impaired microtubule stability. FEBS Lett. 2013;587:245-53 pubmed publisher
Graham C, Matta H, Yang Y, Yi H, Suo Y, Tolani B, et al. Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor-induced growth arrest and apoptosis through NF-?B activation. J Virol. 2013;87:2242-52 pubmed publisher
Agra Andrieu N, Motiño O, Mayoral R, Llorente Izquierdo C, Fernández Alvarez A, Bosca L, et al. Cyclooxygenase-2 is a target of microRNA-16 in human hepatoma cells. PLoS ONE. 2012;7:e50935 pubmed publisher
Ori McKenney K, Jan L, Jan Y. Golgi outposts shape dendrite morphology by functioning as sites of acentrosomal microtubule nucleation in neurons. Neuron. 2012;76:921-30 pubmed publisher
Moghe S, Jiang F, Miura Y, Cerny R, Tsai M, Furukawa M. The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A. Biol Open. 2012;1:82-91 pubmed publisher
Soares F, Tattoli I, Wortzman M, Arnoult D, Philpott D, Girardin S. NLRX1 does not inhibit MAVS-dependent antiviral signalling. Innate Immun. 2013;19:438-48 pubmed publisher
Conklin J, Baker J, Sage J. The RB family is required for the self-renewal and survival of human embryonic stem cells. Nat Commun. 2012;3:1244 pubmed publisher
Kopp F, Oak P, Wagner E, Roidl A. miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. PLoS ONE. 2012;7:e50469 pubmed publisher
Thakran S, Sharma P, Attia R, Hori R, Deng X, Elam M, et al. Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone. J Biol Chem. 2013;288:807-18 pubmed publisher
Quy P, Kuma A, Pierre P, Mizushima N. Proteasome-dependent activation of mammalian target of rapamycin complex 1 (mTORC1) is essential for autophagy suppression and muscle remodeling following denervation. J Biol Chem. 2013;288:1125-34 pubmed publisher
Mourskaia A, Amir E, Dong Z, Tiedemann K, Cory S, Omeroglu A, et al. ABCC5 supports osteoclast formation and promotes breast cancer metastasis to bone. Breast Cancer Res. 2012;14:R149 pubmed publisher
Aranjuez G, Kudlaty E, Longworth M, McDonald J. On the role of PDZ domain-encoding genes in Drosophila border cell migration. G3 (Bethesda). 2012;2:1379-91 pubmed publisher
Williamson S, Hepburn A, Wilson L, Coffey K, Ryan Munden C, Pal D, et al. Human ?(2)?(1)(HI) CD133(+VE) epithelial prostate stem cells express low levels of active androgen receptor. PLoS ONE. 2012;7:e48944 pubmed publisher
Tsuzuki S, Seto M. TEL (ETV6)-AML1 (RUNX1) initiates self-renewing fetal pro-B cells in association with a transcriptional program shared with embryonic stem cells in mice. Stem Cells. 2013;31:236-47 pubmed publisher
Ampofo E, Sokolowsky T, Götz C, Montenarh M. Functional interaction of protein kinase CK2 and activating transcription factor 4 (ATF4), a key player in the cellular stress response. Biochim Biophys Acta. 2013;1833:439-51 pubmed publisher
Hori N, Yamane M, Kouno K, Sato K. Induction of DNA demethylation depending on two sets of Sox2 and adjacent Oct3/4 binding sites (Sox-Oct motifs) within the mouse H19/insulin-like growth factor 2 (Igf2) imprinted control region. J Biol Chem. 2012;287:44006-16 pubmed publisher
Huh M, Price O Dea T, Ouazia D, McKay B, Parise G, Parks R, et al. Compromised genomic integrity impedes muscle growth after Atrx inactivation. J Clin Invest. 2012;122:4412-23 pubmed publisher
Kim K, Lee K, Rhee K. CEP90 is required for the assembly and centrosomal accumulation of centriolar satellites, which is essential for primary cilia formation. PLoS ONE. 2012;7:e48196 pubmed publisher
Lakhal Naouar I, Jardim A, Strasser R, Luo S, Kozakai Y, Nakhasi H, et al. Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis. PLoS Negl Trop Dis. 2012;6:e1849 pubmed publisher
Beshiri M, Holmes K, Richter W, HESS S, Islam A, Yan Q, et al. Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation. Proc Natl Acad Sci U S A. 2012;109:18499-504 pubmed publisher
Kim Y, Spitz G, Veturi U, Lach F, Auerbach A, Smogorzewska A. Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4. Blood. 2013;121:54-63 pubmed publisher
Zhang L, Yang M, Gan L, He T, Xiao X, Stewart M, et al. DLX4 upregulates TWIST and enhances tumor migration, invasion and metastasis. Int J Biol Sci. 2012;8:1178-87 pubmed publisher
Ginkel C, Hartmann D, Vom Dorp K, Zlomuzica A, Farwanah H, Eckhardt M, et al. Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes. J Biol Chem. 2012;287:41888-902 pubmed publisher
Suzuki T, Tsuzuku J, Hayashi A, Shiomi Y, Iwanari H, Mochizuki Y, et al. Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob. J Biol Chem. 2012;287:40256-65 pubmed publisher
Tortorella L, Pipalia N, Mukherjee S, Pastan I, Fitzgerald D, Maxfield F. Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary. PLoS ONE. 2012;7:e47320 pubmed publisher
DuRose J, Li J, Chien S, Spector D. Infection of vascular endothelial cells with human cytomegalovirus under fluid shear stress reveals preferential entry and spread of virus in flow conditions simulating atheroprone regions of the artery. J Virol. 2012;86:13745-55 pubmed publisher
Horani A, Druley T, Zariwala M, Patel A, Levinson B, Van Arendonk L, et al. Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia. Am J Hum Genet. 2012;91:685-93 pubmed publisher
Liu Y, Lv K, Li Z, Yu A, Chen J, Teng J. PACSIN1, a Tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instability. J Biol Chem. 2012;287:39911-24 pubmed publisher
Shiheido H, Naito Y, Kimura H, Genma H, Takashima H, Tokunaga M, et al. An anilinoquinazoline derivative inhibits tumor growth through interaction with hCAP-G2, a subunit of condensin II. PLoS ONE. 2012;7:e44889 pubmed publisher
Allison D, Wamsley J, Kumar M, Li D, Gray L, Hart G, et al. Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-?B acetylation and transcription. Proc Natl Acad Sci U S A. 2012;109:16888-93 pubmed publisher
Bonezzi K, Belotti D, North B, Ghilardi C, Borsotti P, Resovi A, et al. Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies. Neoplasia. 2012;14:846-54 pubmed
Guse A, Fuller C, Straight A. A cell-free system for functional centromere and kinetochore assembly. Nat Protoc. 2012;7:1847-69 pubmed publisher
Ulbricht T, Alzrigat M, Horch A, Reuter N, von Mikecz A, Steimle V, et al. PML promotes MHC class II gene expression by stabilizing the class II transactivator. J Cell Biol. 2012;199:49-63 pubmed publisher
Peng X, Liu T, Wang Y, Yan Q, Jin H, Li L, et al. Wnt/beta-catenin signaling in embryonic stem cell converted tumor cells. J Transl Med. 2012;10:196 pubmed publisher
Chmielewski J, Henderson L, Smith C, Christensen T. Drosophila Psf2 has a role in chromosome condensation. Chromosoma. 2012;121:585-96 pubmed publisher
Darlyuk Saadon I, Weidenfeld Baranboim K, Yokoyama K, Hai T, Aronheim A. The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter. Biochim Biophys Acta. 2012;1819:1142-53 pubmed publisher
Saint Dizier M, Sandra O, Ployart S, Chebrout M, Constant F. Expression of nuclear progesterone receptor and progesterone receptor membrane components 1 and 2 in the oviduct of cyclic and pregnant cows during the post-ovulation period. Reprod Biol Endocrinol. 2012;10:76 pubmed
Matsuda S, Kuwako K, Okano H, Tsutsumi S, Aburatani H, Saga Y, et al. Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. J Neurosci. 2012;32:12543-57 pubmed
Sorrells S, Carbonneau S, Harrington E, Chen A, Hast B, Milash B, et al. Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53. PLoS Genet. 2012;8:e1002922 pubmed publisher
Folker E, Schulman V, Baylies M. Muscle length and myonuclear position are independently regulated by distinct Dynein pathways. Development. 2012;139:3827-37 pubmed
Siesser P, Motolese M, Walker M, Goldfarb D, Gewain K, Yan F, et al. FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. Sci Signal. 2012;5:ra64 pubmed publisher
Gannon A, Frizzell A, Healy E, Lahue R. MutS? and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells. Nucleic Acids Res. 2012;40:10324-33 pubmed publisher
Shimizu K, Takahama S, Endo Y, Sawasaki T. Stress-inducible caspase substrate TRB3 promotes nuclear translocation of procaspase-3. PLoS ONE. 2012;7:e42721 pubmed publisher
Shen J, Wachten S, Halls M, Everett K, Cooper D. Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas G?? subunits exert opposing effects depending on the G-protein source. Biochem J. 2012;447:393-405 pubmed publisher
Enesa K, Ordureau A, Smith H, Barford D, Cheung P, Patterson Kane J, et al. Pellino1 is required for interferon production by viral double-stranded RNA. J Biol Chem. 2012;287:34825-35 pubmed publisher
Abdel Wahab O, Adli M, Lafave L, Gao J, Hricik T, Shih A, et al. ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. Cancer Cell. 2012;22:180-93 pubmed publisher
Gomez Ferreria M, Bashkurov M, Mullin M, Gingras A, Pelletier L. CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly. Cell Cycle. 2012;11:3555-8 pubmed publisher
Amadio M, Osera C, Lupo G, Motta C, Drago F, Govoni S, et al. Protein kinase C activation affects, via the mRNA-binding Hu-antigen R/ELAV protein, vascular endothelial growth factor expression in a pericytic/endothelial coculture model. Mol Vis. 2012;18:2153-64 pubmed
D Amours O, Frenette G, Bordeleau L, Allard N, Leclerc P, Blondin P, et al. Epididymosomes transfer epididymal sperm binding protein 1 (ELSPBP1) to dead spermatozoa during epididymal transit in bovine. Biol Reprod. 2012;87:94 pubmed publisher
Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, et al. Keap1 degradation by autophagy for the maintenance of redox homeostasis. Proc Natl Acad Sci U S A. 2012;109:13561-6 pubmed publisher
Ozaki Y, Matsui H, Asou H, Nagamachi A, Aki D, Honda H, et al. Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation. Mol Cell. 2012;47:694-706 pubmed publisher
Aguilera M, Berón W, Colombo M. The actin cytoskeleton participates in the early events of autophagosome formation upon starvation induced autophagy. Autophagy. 2012;8:1590-603 pubmed publisher
Cornacchia D, Dileep V, Quivy J, Foti R, Tili F, Santarella Mellwig R, et al. Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells. EMBO J. 2012;31:3678-90 pubmed publisher
Chamberlain C, Ranum L. Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise. Hum Mol Genet. 2012;21:4645-54 pubmed publisher
Ferro F, Spelat R, D Aurizio F, Puppato E, Pandolfi M, Beltrami A, et al. Dental pulp stem cells differentiation reveals new insights in Oct4A dynamics. PLoS ONE. 2012;7:e41774 pubmed publisher
Bezler M, Hengstler J, Ullrich A. Inhibition of doxorubicin-induced HER3-PI3K-AKT signalling enhances apoptosis of ovarian cancer cells. Mol Oncol. 2012;6:516-29 pubmed publisher
Oeztuerk Winder F, Guinot A, Ochalek A, Ventura J. Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis. EMBO J. 2012;31:3431-41 pubmed publisher
Kókai E, Páldy F, Somogyi K, Chougule A, Pal M, Kerekes E, et al. CalpB modulates border cell migration in Drosophila egg chambers. BMC Dev Biol. 2012;12:20 pubmed publisher
Hellstrom I, Dhir S, Diorio J, Meaney M. Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFI-A signalling cascade. Philos Trans R Soc Lond B Biol Sci. 2012;367:2495-510 pubmed publisher
Gálvez Santisteban M, Rodriguez Fraticelli A, Bryant D, Vergarajauregui S, Yasuda T, Bañón Rodríguez I, et al. Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nat Cell Biol. 2012;14:838-49 pubmed publisher
Yang N, Inaki M, Cliffe A, Rørth P. Microtubules and Lis-1/NudE/dynein regulate invasive cell-on-cell migration in Drosophila. PLoS ONE. 2012;7:e40632 pubmed publisher
Roesch F, Meziane O, Kula A, Nisole S, Porrot F, Anderson I, et al. Hyperthermia stimulates HIV-1 replication. PLoS Pathog. 2012;8:e1002792 pubmed publisher
Chen R, Xu M, Hogg R, Li J, Little B, Gerard R, et al. The acetylase/deacetylase couple CREB-binding protein/Sirtuin 1 controls hypoxia-inducible factor 2 signaling. J Biol Chem. 2012;287:30800-11 pubmed publisher
Kawamura I, Maeda S, Imamura K, Setoguchi T, Yokouchi M, Ishidou Y, et al. SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-? and bone morphogenetic protein pathways. J Biol Chem. 2012;287:29101-13 pubmed publisher
De Wever V, Lloyd D, Nasa I, Nimick M, Trinkle Mulcahy L, Gourlay R, et al. Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21. PLoS ONE. 2012;7:e39510 pubmed publisher
Ehara T, Kamei Y, Takahashi M, Yuan X, Kanai S, Tamura E, et al. Role of DNA methylation in the regulation of lipogenic glycerol-3-phosphate acyltransferase 1 gene expression in the mouse neonatal liver. Diabetes. 2012;61:2442-50 pubmed
Nandadasa S, Tao Q, Shoemaker A, Cha S, Wylie C. Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesis. PLoS ONE. 2012;7:e38756 pubmed publisher
Tattoli I, Sorbara M, Vuckovic D, Ling A, Soares F, Carneiro L, et al. Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program. Cell Host Microbe. 2012;11:563-75 pubmed publisher
Jo J, Song H, Park S, Lee S, Ko J, Park J, et al. Regulation of differentiation potential of human mesenchymal stem cells by intracytoplasmic delivery of coactivator-associated arginine methyltransferase 1 protein using cell-penetrating peptide. Stem Cells. 2012;30:1703-13 pubmed publisher
Ohmura T, Shioi G, Hirano M, Aizawa S. Neural tube defects by NUAK1 and NUAK2 double mutation. Dev Dyn. 2012;241:1350-64 pubmed publisher
Li H, Song Y, Zhang L, Gu Y, Li F, Pan S, et al. LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid ?-oxidation of lipid droplets. PLoS ONE. 2012;7:e36712 pubmed publisher
Mukherjee S, Diaz Valencia J, Stewman S, Metz J, Monnier S, Rath U, et al. Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis. Cell Cycle. 2012;11:2359-66 pubmed publisher
Fong J, Kells R, Gumpert A, Marzillier J, Davidson M, Falk M. Internalized gap junctions are degraded by autophagy. Autophagy. 2012;8:794-811 pubmed publisher
Kang J, Kwon Y, Ahn B. Modulation of the type I interferon pathways by culture-adaptive hepatitis C virus core mutants. FEBS Lett. 2012;586:1272-8 pubmed publisher
Yang S, Baxter E, Van Doren M. Phf7 controls male sex determination in the Drosophila germline. Dev Cell. 2012;22:1041-51 pubmed publisher
Gomez Ferreria M, Bashkurov M, Helbig A, Larsen B, Pawson T, Gingras A, et al. Novel NEDD1 phosphorylation sites regulate ?-tubulin binding and mitotic spindle assembly. J Cell Sci. 2012;125:3745-51 pubmed publisher
Kudo T, Ikeda M, Nishikawa M, Yang Z, Ohno K, Nakagawa K, et al. The RASSF3 candidate tumor suppressor induces apoptosis and G1-S cell-cycle arrest via p53. Cancer Res. 2012;72:2901-11 pubmed publisher
Zhang W, Zhang J, Hoadley K, Kushwaha D, Ramakrishnan V, Li S, et al. miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression. Neuro Oncol. 2012;14:712-9 pubmed publisher
Happold C, Roth P, Wick W, Schmidt N, Florea A, Silginer M, et al. Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells. J Neurochem. 2012;122:444-55 pubmed publisher
O Sullivan N, Jahn T, Reid E, O Kane C. Reticulon-like-1, the Drosophila orthologue of the hereditary spastic paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons. Hum Mol Genet. 2012;21:3356-65 pubmed publisher
Cabianca D, Casa V, Bodega B, Xynos A, Ginelli E, Tanaka Y, et al. A long ncRNA links copy number variation to a polycomb/trithorax epigenetic switch in FSHD muscular dystrophy. Cell. 2012;149:819-31 pubmed publisher
Kong B, Bernhardt M, Kim A, O Halloran T, Woodruff T. Zinc maintains prophase I arrest in mouse oocytes through regulation of the MOS-MAPK pathway. Biol Reprod. 2012;87:11, 1-12 pubmed publisher
Davila D, Connolly N, Bonner H, Weisová P, Dussmann H, Concannon C, et al. Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate. Cell Death Differ. 2012;19:1677-88 pubmed publisher
Zerlanko B, Bartholin L, Melhuish T, Wotton D. Premature senescence and increased TGFβ signaling in the absence of Tgif1. PLoS ONE. 2012;7:e35460 pubmed publisher
Eckey M, Kuphal S, Straub T, Rümmele P, Kremmer E, Bosserhoff A, et al. Nucleosome remodeler SNF2L suppresses cell proliferation and migration and attenuates Wnt signaling. Mol Cell Biol. 2012;32:2359-71 pubmed publisher
Meng L, Person R, Beaudet A. Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a. Hum Mol Genet. 2012;21:3001-12 pubmed publisher
Cho J, Ryu J, Jeong Y, Park J, Song J, Amasino R, et al. Control of seed germination by light-induced histone arginine demethylation activity. Dev Cell. 2012;22:736-48 pubmed publisher
Sakai D, Dixon J, Dixon M, Trainor P. Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. PLoS Genet. 2012;8:e1002566 pubmed publisher
Ariotti N, Murphy S, Hamilton N, Wu L, Green K, Schieber N, et al. Postlipolytic insulin-dependent remodeling of micro lipid droplets in adipocytes. Mol Biol Cell. 2012;23:1826-37 pubmed publisher
Yu T, Wang C, Lin J. Depleting components of the THO complex causes increased telomere length by reducing the expression of the telomere-associated protein Rif1p. PLoS ONE. 2012;7:e33498 pubmed publisher
Janski N, Masoud K, Batzenschlager M, Herzog E, Evrard J, Houln G, et al. The GCP3-interacting proteins GIP1 and GIP2 are required for ?-tubulin complex protein localization, spindle integrity, and chromosomal stability. Plant Cell. 2012;24:1171-87 pubmed publisher
Takeo S, Swanson S, Nandanan K, Nakai Y, Aigaki T, Washburn M, et al. Shaggy/glycogen synthase kinase 3β and phosphorylation of Sarah/regulator of calcineurin are essential for completion of Drosophila female meiosis. Proc Natl Acad Sci U S A. 2012;109:6382-9 pubmed publisher
Knieke K, Lingel H, Chamaon K, Brunner Weinzierl M. Migration of Th1 lymphocytes is regulated by CD152 (CTLA-4)-mediated signaling via PI3 kinase-dependent Akt activation. PLoS ONE. 2012;7:e31391 pubmed publisher
Tran H, Nimick M, Uhrig R, Templeton G, Morrice N, Gourlay R, et al. Arabidopsis thaliana histone deacetylase 14 (HDA14) is an ?-tubulin deacetylase that associates with PP2A and enriches in the microtubule fraction with the putative histone acetyltransferase ELP3. Plant J. 2012;71:263-72 pubmed publisher
Cole F, Kauppi L, Lange J, Roig I, Wang R, Keeney S, et al. Homeostatic control of recombination is implemented progressively in mouse meiosis. Nat Cell Biol. 2012;14:424-30 pubmed publisher
Yu X, Ajayi A, Boga N, Strom A. Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model. J Mol Neurosci. 2012;47:219-33 pubmed publisher
Sakamori R, Das S, Yu S, Feng S, Stypulkowski E, Guan Y, et al. Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice. J Clin Invest. 2012;122:1052-65 pubmed publisher
Segref A, Hoppe T. Analysis of ubiquitin-dependent proteolysis in Caenorhabditis elegans. Methods Mol Biol. 2012;832:531-44 pubmed publisher
Moore F, Santin I, Nogueira T, Gurzov E, Marselli L, Marchetti P, et al. The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells. PLoS ONE. 2012;7:e31062 pubmed publisher
Lu C, Ward P, Kapoor G, Rohle D, Turcan S, Abdel Wahab O, et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature. 2012;483:474-8 pubmed publisher
Konsavage W, Kyler S, Rennoll S, Jin G, Yochum G. Wnt/?-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells. J Biol Chem. 2012;287:11730-9 pubmed publisher
Zhao H, Chen X, Gurian West M, Roberts J. Loss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication. Mol Cell Biol. 2012;32:1421-32 pubmed publisher
Ma J, Cai H, Wu T, Sobhian B, Huo Y, Alcivar A, et al. PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. Mol Cell Biol. 2012;32:1506-17 pubmed publisher
Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue E, Dragin L, et al. SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nat Immunol. 2012;13:223-228 pubmed publisher
Szerlip N, Pedraza A, Chakravarty D, Azim M, McGuire J, Fang Y, et al. Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proc Natl Acad Sci U S A. 2012;109:3041-6 pubmed publisher
Loubéry S, Delevoye C, Louvard D, Raposo G, Coudrier E. Myosin VI regulates actin dynamics and melanosome biogenesis. Traffic. 2012;13:665-80 pubmed publisher
Farquhar M, Hu K, Harris H, Davis C, Brimacombe C, Fletcher S, et al. Hepatitis C virus induces CD81 and claudin-1 endocytosis. J Virol. 2012;86:4305-16 pubmed publisher
D Orsi B, Bonner H, Tuffy L, Dussmann H, Woods I, Courtney M, et al. Calpains are downstream effectors of bax-dependent excitotoxic apoptosis. J Neurosci. 2012;32:1847-58 pubmed publisher
Bernhardt M, Kong B, Kim A, O Halloran T, Woodruff T. A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes. Biol Reprod. 2012;86:114 pubmed publisher
Childs K, Randall R, Goodbourn S. Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction. J Virol. 2012;86:3411-21 pubmed publisher
Senft D, Berking C, Graf S, Kammerbauer C, Ruzicka T, Besch R. Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. PLoS ONE. 2012;7:e30821 pubmed publisher
Ma L, Yu Y, Guo Y, Hart R, Schachner M. Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish. Eur J Neurosci. 2012;35:353-65 pubmed publisher
Li Y, Wen X, Liu Y. Tubular cell dedifferentiation and peritubular inflammation are coupled by the transcription regulator Id1 in renal fibrogenesis. Kidney Int. 2012;81:880-91 pubmed publisher
Weigert O, Lane A, Bird L, Kopp N, Chapuy B, Van Bodegom D, et al. Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition. J Exp Med. 2012;209:259-73 pubmed publisher
Hanania R, Sun H, Xu K, Pustylnik S, Jeganathan S, Harrison R. Classically activated macrophages use stable microtubules for matrix metalloproteinase-9 (MMP-9) secretion. J Biol Chem. 2012;287:8468-83 pubmed publisher
Uribe V, Wong B, Graham R, Cusack C, Skotte N, Pouladi M, et al. Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice. Hum Mol Genet. 2012;21:1954-67 pubmed publisher
Vinogradova T, Paul R, Grimaldi A, Loncarek J, Miller P, Yampolsky D, et al. Concerted effort of centrosomal and Golgi-derived microtubules is required for proper Golgi complex assembly but not for maintenance. Mol Biol Cell. 2012;23:820-33 pubmed publisher
Ashe A, Butterfield N, Town L, Courtney A, Cooper A, Ferguson C, et al. Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies. Hum Mol Genet. 2012;21:1808-23 pubmed publisher
Jiang Q, Patima S, Ye D, Pan H, Zhang P, Zhang Z. Upregulation of ?2-microglobulin expression in progressive human oral squamous cell carcinoma. Oncol Rep. 2012;27:1058-64 pubmed publisher
Yang H, Sugiura Y, Ikegami K, Konishi Y, Setou M. Axonal gradient of arachidonic acid-containing phosphatidylcholine and its dependence on actin dynamics. J Biol Chem. 2012;287:5290-300 pubmed publisher
Lund N, Milev M, Wong R, Sanmuganantham T, Woolaway K, Chabot B, et al. Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression. Nucleic Acids Res. 2012;40:3663-75 pubmed publisher
Shaposhnikov D, Descot A, Schilling J, Posern G. Myocardin-related transcription factor A regulates expression of Bok and Noxa and is involved in apoptotic signalling. Cell Cycle. 2012;11:141-50 pubmed publisher
Martin L, Rainey M, Santocanale C, Gardner L. Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation. Oncogene. 2012;31:4076-84 pubmed publisher
Hartmaier R, Richter A, Gillihan R, Sallit J, McGuire S, Wang J, et al. A SNP in steroid receptor coactivator-1 disrupts a GSK3? phosphorylation site and is associated with altered tamoxifen response in bone. Mol Endocrinol. 2012;26:220-7 pubmed publisher
Lee K, Minami A, Marshall R, Book A, Farmer L, Walker J, et al. The RPT2 subunit of the 26S proteasome directs complex assembly, histone dynamics, and gametophyte and sporophyte development in Arabidopsis. Plant Cell. 2011;23:4298-317 pubmed publisher
Yamagishi N, Ueda T, Mori A, Saito Y, Hatayama T. Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice. Biochem Biophys Res Commun. 2012;417:364-70 pubmed publisher
Zhang Z, Kakutani K, Maeno K, Takada T, Yurube T, Doita M, et al. Expression of silent mating type information regulator 2 homolog 1 and its role in human intervertebral disc cell homeostasis. Arthritis Res Ther. 2011;13:R200 pubmed publisher
González Arenas A, Hansberg Pastor V, Hernández Hernández O, González García T, Henderson Villalpando J, Lemus Hernández D, et al. Estradiol increases cell growth in human astrocytoma cell lines through ER? activation and its interaction with SRC-1 and SRC-3 coactivators. Biochim Biophys Acta. 2012;1823:379-86 pubmed publisher
Milani L, Ghiselli F, Maurizii M, Passamonti M. Doubly uniparental inheritance of mitochondria as a model system for studying germ line formation. PLoS ONE. 2011;6:e28194 pubmed publisher
Bräutigam L, Schütte L, Godoy J, Prozorovski T, Gellert M, Hauptmann G, et al. Vertebrate-specific glutaredoxin is essential for brain development. Proc Natl Acad Sci U S A. 2011;108:20532-7 pubmed publisher
Huang Y, Liu H, Ge R, Zhou Y, Lou X, Wang C. UXT-V1 facilitates the formation of MAVS antiviral signalosome on mitochondria. J Immunol. 2012;188:358-66 pubmed publisher
Zanin E, Dumont J, Gassmann R, CHEESEMAN I, Maddox P, Bahmanyar S, et al. Affinity purification of protein complexes in C. elegans. Methods Cell Biol. 2011;106:289-322 pubmed publisher
Obrador Hevia A, Serra Sitjar M, Rodriguez J, Villalonga P, Fernandez De Mattos S. The tumour suppressor FOXO3 is a key regulator of mantle cell lymphoma proliferation and survival. Br J Haematol. 2012;156:334-45 pubmed publisher
Maniar T, Kaplan M, Wang G, Shen K, Wei L, Shaw J, et al. UNC-33 (CRMP) and ankyrin organize microtubules and localize kinesin to polarize axon-dendrite sorting. Nat Neurosci. 2011;15:48-56 pubmed publisher
Gutierrez L, Oktaba K, Scheuermann J, Gambetta M, Ly Hartig N, Muller J. The role of the histone H2A ubiquitinase Sce in Polycomb repression. Development. 2012;139:117-27 pubmed publisher
Kaufer S, Coffey C, Parker J. The cellular chaperone hsc70 is specifically recruited to reovirus viral factories independently of its chaperone function. J Virol. 2012;86:1079-89 pubmed publisher
Martinez Glez V, Valencia M, Caparrós Martín J, Aglan M, Temtamy S, Tenorio J, et al. Identification of a mutation causing deficient BMP1/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta. Hum Mutat. 2012;33:343-50 pubmed publisher
Ferro M, Giuberti G, Zappavigna S, Perdonà S, Facchini G, Sperlongano P, et al. Chondroitin sulphate enhances the antitumor activity of gemcitabine and mitomycin-C in bladder cancer cells with different mechanisms. Oncol Rep. 2012;27:409-15 pubmed publisher
Anton R, Chatterjee S, Simundza J, Cowin P, DasGupta R. A systematic screen for micro-RNAs regulating the canonical Wnt pathway. PLoS ONE. 2011;6:e26257 pubmed publisher
Mühlhans J, Brandstätter J, Giessl A. The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors. PLoS ONE. 2011;6:e26496 pubmed publisher
Nieto P, Valdez D, Acosta Rodríguez V, Guido M. Expression of novel opsins and intrinsic light responses in the mammalian retinal ganglion cell line RGC-5. Presence of OPN5 in the rat retina. PLoS ONE. 2011;6:e26417 pubmed publisher
Batut J, Duboé C, Vandel L. The methyltransferases PRMT4/CARM1 and PRMT5 control differentially myogenesis in zebrafish. PLoS ONE. 2011;6:e25427 pubmed publisher
VanBrocklin M, Robinson J, Lastwika K, McKinney A, Gach H, Holmen S. Ink4a/Arf loss promotes tumor recurrence following Ras inhibition. Neuro Oncol. 2012;14:34-42 pubmed publisher
Hussein O, Tiedemann K, Murshed M, Komarova S. Rapamycin inhibits osteolysis and improves survival in a model of experimental bone metastases. Cancer Lett. 2012;314:176-84 pubmed publisher
Greer E, Maures T, Ucar D, Hauswirth A, Mancini E, Lim J, et al. Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature. 2011;479:365-71 pubmed publisher
Shariftabrizi A, Ahmadian S, Pazhang Y. Dynamics of γ-tubulin cytoskeleton in HL-60 leukemia cells undergoing differentiation and apoptosis by all-trans retinoic acid. Mol Med Rep. 2012;5:545-51 pubmed publisher
Brownlee C, Klebba J, Buster D, Rogers G. The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification. J Cell Biol. 2011;195:231-43 pubmed publisher
Thumkeo D, Shinohara R, Watanabe K, Takebayashi H, Toyoda Y, Tohyama K, et al. Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia. PLoS ONE. 2011;6:e25465 pubmed publisher
Sun H, Wilde A, Harrison R. Chlamydia trachomatis inclusions induce asymmetric cleavage furrow formation and ingression failure in host cells. Mol Cell Biol. 2011;31:5011-22 pubmed publisher
Choi P, van Riggelen J, Gentles A, Bachireddy P, Rakhra K, Adam S, et al. Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction. Proc Natl Acad Sci U S A. 2011;108:17432-7 pubmed publisher
Ghosh A, Coppens I, Gardsvoll H, Ploug M, Jacobs Lorena M. Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut. Proc Natl Acad Sci U S A. 2011;108:17153-8 pubmed publisher
Hereng T, Elgstøen K, Cederkvist F, Eide L, Jahnsen T, Skalhegg B, et al. Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa. Hum Reprod. 2011;26:3249-63 pubmed publisher
Castiel A, Visochek L, Mittelman L, Dantzer F, Izraeli S, Cohen Armon M. A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells. BMC Cancer. 2011;11:412 pubmed publisher
Ait Mohamed O, Battisti V, Joliot V, Fritsch L, Pontis J, Medjkane S, et al. Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells. PLoS ONE. 2011;6:e24537 pubmed publisher
Zhang T, Dayanandan B, Rouiller I, Lawrence E, Mandato C. Growth-arrest-specific protein 2 inhibits cell division in Xenopus embryos. PLoS ONE. 2011;6:e24698 pubmed publisher
Matsushita N, Endo Y, Sato K, Kurumizaka H, Yamashita T, Takata M, et al. Direct inhibition of TNF-? promoter activity by Fanconi anemia protein FANCD2. PLoS ONE. 2011;6:e23324 pubmed publisher
Moree B, Meyer C, Fuller C, Straight A. CENP-C recruits M18BP1 to centromeres to promote CENP-A chromatin assembly. J Cell Biol. 2011;194:855-71 pubmed publisher
Thibaut H, De Palma A, Neyts J. Combating enterovirus replication: state-of-the-art on antiviral research. Biochem Pharmacol. 2012;83:185-92 pubmed publisher
Do M, Sato Y, Shimizu N, Suzuki T, Shono J, Mizunoya W, et al. Growth factor regulation of neural chemorepellent Sema3A expression in satellite cell cultures. Am J Physiol Cell Physiol. 2011;301:C1270-9 pubmed publisher
Min T, Kriebel M, Hou S, Pera E. The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo. Dev Biol. 2011;358:262-76 pubmed publisher
Watters K, Palmenberg A. Differential processing of nuclear pore complex proteins by rhinovirus 2A proteases from different species and serotypes. J Virol. 2011;85:10874-83 pubmed publisher
Wang D, Dai C, Li Y, Liu Y. Canonical Wnt/?-catenin signaling mediates transforming growth factor-?1-driven podocyte injury and proteinuria. Kidney Int. 2011;80:1159-1169 pubmed publisher
Kiok K, Sun H, Clancy H, Bose S, Kluz T, Wu F, et al. Liprin-α4 is required for nickel induced receptor protein tyrosine phosphatase-leukocyte antigen related receptor F (RPTP-LAR) activity. PLoS ONE. 2011;6:e22764 pubmed publisher
Seisenbacher G, Hafen E, Stocker H. MK2-dependent p38b signalling protects Drosophila hindgut enterocytes against JNK-induced apoptosis under chronic stress. PLoS Genet. 2011;7:e1002168 pubmed publisher
Bortolanza S, Nonis A, Sanvito F, Maciotta S, Sitia G, Wei J, et al. AAV6-mediated systemic shRNA delivery reverses disease in a mouse model of facioscapulohumeral muscular dystrophy. Mol Ther. 2011;19:2055-64 pubmed publisher
Varodayan F, Pignataro L, Harrison N. Alcohol induces synaptotagmin 1 expression in neurons via activation of heat shock factor 1. Neuroscience. 2011;193:63-71 pubmed publisher
Slone S, Lesort M, Yacoubian T. 14-3-3theta protects against neurotoxicity in a cellular Parkinson's disease model through inhibition of the apoptotic factor Bax. PLoS ONE. 2011;6:e21720 pubmed publisher
Trapani L, Melli L, Segatto M, Trezza V, Campolongo P, Jozwiak A, et al. Effects of myosin heavy chain (MHC) plasticity induced by HMGCoA-reductase inhibition on skeletal muscle functions. FASEB J. 2011;25:4037-47 pubmed publisher
Darbellay B, Arnaudeau S, Bader C, Konig S, Bernheim L. STIM1L is a new actin-binding splice variant involved in fast repetitive Ca2+ release. J Cell Biol. 2011;194:335-46 pubmed publisher
Tang Y, Orth J, Xie T, Mitchison T. Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells. Cancer Lett. 2011;310:15-24 pubmed publisher
Wu C, Guo X, Wang F, Li X, Tian X, Li L, et al. Simulated microgravity compromises mouse oocyte maturation by disrupting meiotic spindle organization and inducing cytoplasmic blebbing. PLoS ONE. 2011;6:e22214 pubmed publisher
Uezu A, Umeda K, Tsujita K, Suetsugu S, Takenawa T, Nakanishi H. Characterization of the EFC/F-BAR domain protein, FCHO2. Genes Cells. 2011;16:868-78 pubmed publisher
Sánchez Molina S, Mortusewicz O, Bieber B, Auer S, Eckey M, Leonhardt H, et al. Role for hACF1 in the G2/M damage checkpoint. Nucleic Acids Res. 2011;39:8445-56 pubmed publisher
Pfaff N, Lachmann N, Kohlscheen S, Sgodda M, Arauzo Bravo M, Greber B, et al. Efficient hematopoietic redifferentiation of induced pluripotent stem cells derived from primitive murine bone marrow cells. Stem Cells Dev. 2012;21:689-701 pubmed publisher
Le Masson F, Razak Z, Kaigo M, Audouard C, Charry C, Cooke H, et al. Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis. Mol Cell Biol. 2011;31:3410-23 pubmed publisher
Shepelev M, Chernoff J, Korobko I. Rho family GTPase Chp/RhoV induces PC12 apoptotic cell death via JNK activation. Small Gtpases. 2011;2:17-26 pubmed
Wong R, Balachandran A, Mao A, Dobson W, Gray Owen S, Cochrane A. Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy. Retrovirology. 2011;8:47 pubmed publisher
Pernicová Z, Slabáková E, Kharaishvili G, Bouchal J, Kral M, Kunická Z, et al. Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2. Neoplasia. 2011;13:526-36 pubmed
Bobrowska A, Paganetti P, Matthias P, Bates G. Hdac6 knock-out increases tubulin acetylation but does not modify disease progression in the R6/2 mouse model of Huntington's disease. PLoS ONE. 2011;6:e20696 pubmed publisher
Zhaorigetu S, Yang Z, Toma I, McCaffrey T, Hu C. Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells. J Biol Chem. 2011;286:27389-98 pubmed publisher
Sashida G, Bae N, Di Giandomenico S, Asai T, Gurvich N, Bazzoli E, et al. The mef/elf4 transcription factor fine tunes the DNA damage response. Cancer Res. 2011;71:4857-65 pubmed publisher
Gibbens Y, Warren J, Gilbert L, O Connor M. Neuroendocrine regulation of Drosophila metamorphosis requires TGFbeta/Activin signaling. Development. 2011;138:2693-703 pubmed publisher
Dubas E, Wedzony M, Custers J, Kieft H, Van Lammeren A. Gametophytic development of Brassica napus pollen in vitroenables examination of cytoskeleton and nuclear movements. Protoplasma. 2012;249:369-77 pubmed publisher
Sabatini P, Zhang M, Silverman Gavrila R, Bendeck M. Cadherins at cell-autonomous membrane contacts control macropinocytosis. J Cell Sci. 2011;124:2013-20 pubmed publisher
Iempridee T, Das S, Xu I, Mertz J. Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene. J Virol. 2011;85:7836-48 pubmed publisher
Yi Z, Pan T, Wu X, Song W, Wang S, Xu Y, et al. Hepatitis C virus co-opts Ras-GTPase-activating protein-binding protein 1 for its genome replication. J Virol. 2011;85:6996-7004 pubmed publisher
Takasugi N, Sasaki T, Suzuki K, Osawa S, Isshiki H, Hori Y, et al. BACE1 activity is modulated by cell-associated sphingosine-1-phosphate. J Neurosci. 2011;31:6850-7 pubmed publisher
Gilroy C, Olenyik T, Roberts S, Ullman B. Spermidine synthase is required for virulence of Leishmania donovani. Infect Immun. 2011;79:2764-9 pubmed publisher
Sato S, Trackman P, Maki J, Myllyharju J, Kirsch K, Sonenshein G. The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. Mol Cell Biol. 2011;31:2683-95 pubmed publisher
Bauer M, O Connell D, Maj M, Wagner L, Cahill D, Linse S. Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion. Mol Biosyst. 2011;7:2196-204 pubmed publisher
Isono T. O-GlcNAc-specific antibody CTD110.6 cross-reacts with N-GlcNAc2-modified proteins induced under glucose deprivation. PLoS ONE. 2011;6:e18959 pubmed publisher
Wood J, Pring M, Eveson J, Price N, Proby C, Hague A. Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis. Br J Cancer. 2011;104:1459-71 pubmed publisher
Ferro F, Spelat R, Falini G, Gallelli A, D Aurizio F, Puppato E, et al. Adipose tissue-derived stem cell in vitro differentiation in a three-dimensional dental bud structure. Am J Pathol. 2011;178:2299-310 pubmed publisher
Pruliere G, Cosson J, Chevalier S, Sardet C, Chenevert J. Atypical protein kinase C controls sea urchin ciliogenesis. Mol Biol Cell. 2011;22:2042-53 pubmed publisher
Li vin Le Moal V, Comenge Y, Ruby V, Amsellem R, Nicolas V, Servin A. Secreted autotransporter toxin (Sat) triggers autophagy in epithelial cells that relies on cell detachment. Cell Microbiol. 2011;13:992-1013 pubmed publisher
Song M, Liu Y, Anderson D, Jahng W, O Connell K. Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors. Dev Cell. 2011;20:563-71 pubmed publisher
Wagner P, Otomo A, Christians J. Regulation of pregnancy-associated plasma protein A2 (PAPPA2) in a human placental trophoblast cell line (BeWo). Reprod Biol Endocrinol. 2011;9:48 pubmed publisher
Vollmer L, Jimenez M, Camarco D, Zhu W, Daghestani H, Balachandran R, et al. A simplified synthesis of novel dictyostatin analogues with in vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos. Mol Cancer Ther. 2011;10:994-1006 pubmed publisher
de Vries E, Tscherne D, Wienholts M, Cobos Jiménez V, Scholte F, Garcia Sastre A, et al. Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway. PLoS Pathog. 2011;7:e1001329 pubmed publisher
Miyamoto K, Nagai K, Kitamura N, Nishikawa T, Ikegami H, Binh N, et al. Identification and characterization of an oocyte factor required for development of porcine nuclear transfer embryos. Proc Natl Acad Sci U S A. 2011;108:7040-5 pubmed publisher
Jeanes A, Maya Mendoza A, Streuli C. Cellular microenvironment influences the ability of mammary epithelia to undergo cell cycle. PLoS ONE. 2011;6:e18144 pubmed publisher
Kim C, Sakamoto K, Tambe Y, Inoue H. Opposite regulation of epithelial-to-mesenchymal transition and cell invasiveness by periostin between prostate and bladder cancer cells. Int J Oncol. 2011;38:1759-66 pubmed publisher
Baldeyron C, Soria G, Roche D, Cook A, Almouzni G. HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. J Cell Biol. 2011;193:81-95 pubmed publisher
Yu Y, Gibbs K, Davila J, Campbell N, Sung S, Todorova T, et al. MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. Eur J Neurosci. 2011;33:1587-97 pubmed publisher
Ferreira A, Bigio E. Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathies. Mol Med. 2011;17:676-85 pubmed publisher
Regnard C, Straub T, Mitterweger A, Dahlsveen I, Fabian V, Becker P. Global analysis of the relationship between JIL-1 kinase and transcription. PLoS Genet. 2011;7:e1001327 pubmed publisher
Zeitlin S, Chapados B, Baker N, Tai C, Slupphaug G, Wang J. Uracil DNA N-glycosylase promotes assembly of human centromere protein A. PLoS ONE. 2011;6:e17151 pubmed publisher
Yu X, McCarthy P, Lim H, Iempridee T, Kraus R, Gorlen D, et al. The ZIIR element of the Epstein-Barr virus BZLF1 promoter plays a central role in establishment and maintenance of viral latency. J Virol. 2011;85:5081-90 pubmed publisher
Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M. TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol. 2011;192:781-95 pubmed publisher
Fernández Muñoz B, Yurrita M, Martín Villar E, Carrasco Ramirez P, Megias D, Renart J, et al. The transmembrane domain of podoplanin is required for its association with lipid rafts and the induction of epithelial-mesenchymal transition. Int J Biochem Cell Biol. 2011;43:886-96 pubmed publisher
van der Velden Y, Wang L, Zevenhoven J, van Rooijen E, Van Lohuizen M, Giles R, et al. The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish. Proc Natl Acad Sci U S A. 2011;108:4358-63 pubmed publisher
Luu O, David R, Ninomiya H, Winklbauer R. Large-scale mechanical properties of Xenopus embryonic epithelium. Proc Natl Acad Sci U S A. 2011;108:4000-5 pubmed publisher
Lee C, Dykema K, Hawkins D, Cherba D, Webb C, Furge K, et al. MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells. PLoS ONE. 2011;6:e17165 pubmed publisher
Gueye Y, Ferhat L, Sbai O, Bianco J, Ould Yahoui A, Bernard A, et al. Trafficking and secretion of matrix metalloproteinase-2 in olfactory ensheathing glial cells: A role in cell migration?. Glia. 2011;59:750-70 pubmed publisher
Alm Kristiansen A, Lorenzo P, Molværsmyr A, Matre V, Ledsaak M, Sæther T, et al. PIAS1 interacts with FLASH and enhances its co-activation of c-Myb. Mol Cancer. 2011;10:21 pubmed publisher
Gibert J, Karch F. The Polycomb group protein CRAMPED is involved with TRF2 in the activation of the histone H1 gene. Chromosoma. 2011;120:297-307 pubmed publisher
Musumeci G, Cardile V, Fenga C, Caggia S, Loreto C. Mineral fibre toxicity: expression of retinoblastoma (Rb) and phospho-retinoblastoma (pRb) protein in alveolar epithelial and mesothelial cell lines exposed to fluoro-edenite fibres. Cell Biol Toxicol. 2011;27:217-25 pubmed publisher
Huang Y, Chen L, Zhou Y, Liu H, Yang J, Liu Z, et al. UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation. Mol Biol Cell. 2011;22:1389-97 pubmed publisher
Li H, Daculsi R, Grellier M, Bareille R, Bourget C, Remy M, et al. The role of vascular actors in two dimensional dialogue of human bone marrow stromal cell and endothelial cell for inducing self-assembled network. PLoS ONE. 2011;6:e16767 pubmed publisher
Abe M, Havre P, Urasaki Y, Ohnuma K, Morimoto C, Dang L, et al. Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines. BMC Cancer. 2011;11:51 pubmed publisher
Al Jallad H, Myneni V, Piercy Kotb S, Chabot N, Mulani A, Keillor J, et al. Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics. PLoS ONE. 2011;6:e15893 pubmed publisher
Elaković I, Djordjevic A, Adzic M, Djordjevic J, Radojcic M, Matić G. Gender-specific response of brain corticosteroid receptors to stress and fluoxetine. Brain Res. 2011;1384:61-8 pubmed publisher
Boehler C, Gauthier L, Mortusewicz O, Biard D, Saliou J, Bresson A, et al. Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression. Proc Natl Acad Sci U S A. 2011;108:2783-8 pubmed publisher
Lalmansingh A, Urekar C, Reddi P. TDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo. J Biol Chem. 2011;286:10970-82 pubmed publisher
Koike S, Yutoh Y, Keino Masu K, Noji S, Masu M, Ohuchi H. Autotaxin is required for the cranial neural tube closure and establishment of the midbrain-hindbrain boundary during mouse development. Dev Dyn. 2011;240:413-21 pubmed publisher
Castiel A, Danieli M, David A, Moshkovitz S, Aplan P, Kirsch I, et al. The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr. J Cell Sci. 2011;124:532-9 pubmed publisher
Hanashiro K, Brancaccio M, Fukasawa K. Activated ROCK II by-passes the requirement of the CDK2 activity for centrosome duplication and amplification. Oncogene. 2011;30:2188-97 pubmed publisher
Poburko D, Santo Domingo J, Demaurex N. Dynamic regulation of the mitochondrial proton gradient during cytosolic calcium elevations. J Biol Chem. 2011;286:11672-84 pubmed publisher
Warsch W, Kollmann K, Eckelhart E, Fajmann S, Cerny Reiterer S, Hölbl A, et al. High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia. Blood. 2011;117:3409-20 pubmed publisher
Perez V, Ali Z, Alastalo T, Ikeno F, Sawada H, Lai Y, et al. BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways. J Cell Biol. 2011;192:171-88 pubmed publisher
Asally M, Yasuda Y, Oka M, Otsuka S, Yoshimura S, Takeyasu K, et al. Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis. FEBS J. 2011;278:610-21 pubmed publisher
de Oliveira V, Almeida S, Soares H, Crespo A, Marshall Clarke S, Parkhouse R. A novel TLR3 inhibitor encoded by African swine fever virus (ASFV). Arch Virol. 2011;156:597-609 pubmed publisher
Murphy S, Martin S, Parton R. Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens. PLoS ONE. 2010;5:e15030 pubmed publisher
Montembault E, Zhang W, Przewloka M, Archambault V, Sevin E, Laue E, et al. Nessun Dorma, a novel centralspindlin partner, is required for cytokinesis in Drosophila spermatocytes. J Cell Biol. 2010;191:1351-65 pubmed publisher
Araki T, Kusakabe M, Nishida E. A transmembrane protein EIG121L is required for epidermal differentiation during early embryonic development. J Biol Chem. 2011;286:6760-8 pubmed publisher
Breuer M, Kolano A, Kwon M, Li C, Tsai T, Pellman D, et al. HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells. J Cell Biol. 2010;191:1251-60 pubmed publisher
Ozaki Y, Matsui H, Nagamachi A, Asou H, Aki D, Inaba T. The dynactin complex maintains the integrity of metaphasic centrosomes to ensure transition to anaphase. J Biol Chem. 2011;286:5589-98 pubmed publisher
Dussupt V, Sette P, Bello N, Javid M, Nagashima K, Bouamr F. Basic residues in the nucleocapsid domain of Gag are critical for late events of HIV-1 budding. J Virol. 2011;85:2304-15 pubmed publisher
Wacker S, Alvarado C, von Wichert G, Knippschild U, Wiedenmann J, Clauss K, et al. RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J. EMBO J. 2011;30:43-56 pubmed publisher
Rai A, Nöthe H, Tzvetkov N, Korenbaum E, Manstein D. Dictyostelium dynamin B modulates cytoskeletal structures and membranous organelles. Cell Mol Life Sci. 2011;68:2751-67 pubmed publisher
Carmignac V, Quere R, Durbeej M. Proteasome inhibition improves the muscle of laminin ?2 chain-deficient mice. Hum Mol Genet. 2011;20:541-52 pubmed publisher
Meyer R, Delaage M, Rosset R, Capri M, Ait Ahmed O. A single mutation results in diploid gamete formation and parthenogenesis in a Drosophila yemanuclein-alpha meiosis I defective mutant. BMC Genet. 2010;11:104 pubmed publisher
Bernhardt M, Kim A, O Halloran T, Woodruff T. Zinc requirement during meiosis I-meiosis II transition in mouse oocytes is independent of the MOS-MAPK pathway. Biol Reprod. 2011;84:526-36 pubmed publisher
Wirt S, Adler A, Gebala V, Weimann J, Schaffer B, Saddic L, et al. G1 arrest and differentiation can occur independently of Rb family function. J Cell Biol. 2010;191:809-25 pubmed publisher
Hoang M, Nagy J, Fox J, Senger D. Moderation of calpain activity promotes neovascular integration and lumen formation during VEGF-induced pathological angiogenesis. PLoS ONE. 2010;5:e13612 pubmed publisher
Rolland D, Raharijaona M, Barbarat A, Houlgatte R, Thieblemont C. Inhibition of GST-pi nuclear transfer increases mantle cell lymphoma sensitivity to cisplatin, cytarabine, gemcitabine, bortezomib and doxorubicin. Anticancer Res. 2010;30:3951-7 pubmed
Moore F, Naamane N, Colli M, Bouckenooghe T, Ortis F, Gurzov E, et al. STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation. J Biol Chem. 2011;286:929-41 pubmed publisher
Mitchell J, Mansfeld J, Capitanio J, Kutay U, Wozniak R. Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane. J Cell Biol. 2010;191:505-21 pubmed publisher
Jin F, Hamada M, Malureanu L, Jeganathan K, Zhou W, Morbeck D, et al. Cdc20 is critical for meiosis I and fertility of female mice. PLoS Genet. 2010;6:e1001147 pubmed publisher
Blazquez C, Chiarlone A, Sagredo O, Aguado T, Pazos M, Resel E, et al. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain. 2011;134:119-36 pubmed publisher
Ge F, Xiao C, Bi L, Tao S, Xiong S, Yin X, et al. Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells. PLoS ONE. 2010;5: pubmed publisher
von Schubert C, Xue G, Schmuckli Maurer J, Woods K, Nigg E, Dobbelaere D. The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. PLoS Biol. 2010;8: pubmed publisher
Villa Morales M, González Gugel E, Shahbazi M, Santos J, Fernandez Piqueras J. Modulation of the Fas-apoptosis-signalling pathway by functional polymorphisms at Fas, FasL and Fadd and their implication in T-cell lymphoblastic lymphoma susceptibility. Carcinogenesis. 2010;31:2165-71 pubmed publisher
Shimada N, Inouye K, Sawai S, Kawata T. SunB, a novel Sad1 and UNC-84 domain-containing protein required for development of Dictyostelium discoideum. Dev Growth Differ. 2010;52:577-90 pubmed publisher
Larsen R, Gozzelino R, Jeney V, Tokaji L, Bozza F, Japiassu A, et al. A central role for free heme in the pathogenesis of severe sepsis. Sci Transl Med. 2010;2:51ra71 pubmed publisher
Teixido Travesa N, Villen J, Lacasa C, Bertran M, Archinti M, Gygi S, et al. The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8. Mol Biol Cell. 2010;21:3963-72 pubmed publisher
Hussein O, Tiedemann K, Komarova S. Breast cancer cells inhibit spontaneous and bisphosphonate-induced osteoclast apoptosis. Bone. 2011;48:202-11 pubmed publisher
Whyte J, Thornton L, McNally S, McCarthy S, Lanigan F, Gallagher W, et al. PKCzeta regulates cell polarisation and proliferation restriction during mammary acinus formation. J Cell Sci. 2010;123:3316-28 pubmed publisher
Newton I, Kenneth N, Appleton P, Näthke I, Rocha S. Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection. Mol Biol Cell. 2010;21:3630-8 pubmed publisher
Orsi G, Joyce E, Couble P, McKim K, Loppin B. Drosophila I-R hybrid dysgenesis is associated with catastrophic meiosis and abnormal zygote formation. J Cell Sci. 2010;123:3515-24 pubmed publisher
Kim D, Sung S. The Plant Homeo Domain finger protein, VIN3-LIKE 2, is necessary for photoperiod-mediated epigenetic regulation of the floral repressor, MAF5. Proc Natl Acad Sci U S A. 2010;107:17029-34 pubmed publisher
Archinti M, Lacasa C, Teixido Travesa N, Lüders J. SPICE--a previously uncharacterized protein required for centriole duplication and mitotic chromosome congression. J Cell Sci. 2010;123:3039-46 pubmed publisher
Gómora Arrati P, González Arenas A, Balandrán Ruiz M, Mendoza Magana M, González Flores O, Camacho Arroyo I. Changes in the content of GFAP in the rat brain during pregnancy and the beginning of lactation. Neurosci Lett. 2010;484:197-200 pubmed publisher
Garcia Rodriguez L, Abate Daga D, Rojas A, Gonzalez J, Fillat C. E-cadherin contributes to the bystander effect of TK/GCV suicide therapy and enhances its antitumoral activity in pancreatic cancer models. Gene Ther. 2011;18:73-81 pubmed publisher
DeLuca J. Kinetochore-microtubule dynamics and attachment stability. Methods Cell Biol. 2010;97:53-79 pubmed publisher
Liu F, Singh A, Yang Z, Garcia A, Kong Y, Meyskens F. MiTF links Erk1/2 kinase and p21 CIP1/WAF1 activation after UVC radiation in normal human melanocytes and melanoma cells. Mol Cancer. 2010;9:214 pubmed publisher
Zhu H, Yue J, Pan Z, Wu H, Cheng Y, Lu H, et al. Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining. PLoS ONE. 2010;5:e12055 pubmed publisher
Tobaben S, Grohm J, Seiler A, Conrad M, Plesnila N, Culmsee C. Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons. Cell Death Differ. 2011;18:282-92 pubmed publisher
Fong J, Le Nihouannen D, Komarova S. Tumor-supportive and osteoclastogenic changes induced by breast cancer-derived factors are reversed by inhibition of {gamma}-secretase. J Biol Chem. 2010;285:31427-34 pubmed publisher
Honda T, Yamamoto H, Ishii A, Inui M. PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling. Mol Biol Cell. 2010;21:3269-77 pubmed publisher
Thoren L, Nørgaard G, Weischenfeldt J, Waage J, Jakobsen J, Damgaard I, et al. UPF2 is a critical regulator of liver development, function and regeneration. PLoS ONE. 2010;5:e11650 pubmed publisher
Recino A, Sherwood V, Flaxman A, Cooper W, Latif F, Ward A, et al. Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis. Biochem J. 2010;430:207-13 pubmed publisher
Ferro F, Falini G, Spelat R, D Aurizio F, Puppato E, Pandolfi M, et al. Biochemical and biophysical analyses of tissue-engineered bone obtained from three-dimensional culture of a subset of bone marrow mesenchymal stem cells. Tissue Eng Part A. 2010;16:3657-67 pubmed publisher
Sanville B, Dolan M, Wollenberg K, Yan Y, Martin C, Yeung M, et al. Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove. PLoS Pathog. 2010;6:e1000974 pubmed publisher
Abate Daga D, Garcia Rodríguez L, Sumoy L, Fillat C. Cell cycle control pathways act as conditioning factors for TK/GCV sensitivity in pancreatic cancer cells. Biochim Biophys Acta. 2010;1803:1175-85 pubmed publisher
Shah M, Vasanthakumar A, Barnes N, Figueroa M, Kamp A, Hendrick C, et al. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Res. 2010;70:5840-50 pubmed publisher
Burkhart D, Wirt S, Zmoos A, Kareta M, Sage J. Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions. PLoS Genet. 2010;6:e1001003 pubmed publisher
Amatori S, Bagaloni I, Macedi E, Formica M, Giorgi L, Fusi V, et al. Malten, a new synthetic molecule showing in vitro antiproliferative activity against tumour cells and induction of complex DNA structural alterations. Br J Cancer. 2010;103:239-48 pubmed publisher
Salvetti P, Buff S, Afanassieff M, Daniel N, Guérin P, Joly T. Structural, metabolic and developmental evaluation of ovulated rabbit oocytes before and after cryopreservation by vitrification and slow freezing. Theriogenology. 2010;74:847-55 pubmed publisher
Danielson L, Menendez S, Attolini C, Guijarro M, Bisogna M, Wei J, et al. A differentiation-based microRNA signature identifies leiomyosarcoma as a mesenchymal stem cell-related malignancy. Am J Pathol. 2010;177:908-17 pubmed publisher
Zhang L, Gavin T, DeCaprio A, LoPachin R. Gamma-diketone axonopathy: analyses of cytoskeletal motors and highways in CNS myelinated axons. Toxicol Sci. 2010;117:180-9 pubmed publisher
Kantidakis T, Ramsbottom B, Birch J, Dowding S, White R. mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1. Proc Natl Acad Sci U S A. 2010;107:11823-8 pubmed publisher
Suzuki M, Hara Y, Takagi C, Yamamoto T, Ueno N. MID1 and MID2 are required for Xenopus neural tube closure through the regulation of microtubule organization. Development. 2010;137:2329-39 pubmed publisher
Jiang Q, Pan H, Ye D, Zhang P, Zhong L, Zhang Z. Downregulation of tapasin expression in primary human oral squamous cell carcinoma: association with clinical outcome. Tumour Biol. 2010;31:451-9 pubmed publisher
Fuchs F, Pau G, Kranz D, Sklyar O, Budjan C, Steinbrink S, et al. Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Mol Syst Biol. 2010;6:370 pubmed publisher
Shiwaku H, Yoshimura N, Tamura T, Sone M, Ogishima S, Watase K, et al. Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. EMBO J. 2010;29:2446-60 pubmed publisher
Alberti A, Michelet X, Djeddi A, Legouis R. The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans. Autophagy. 2010;6:622-33 pubmed publisher
Seki Y, Kurisaki A, Watanabe Susaki K, Nakajima Y, Nakanishi M, Arai Y, et al. TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner. Proc Natl Acad Sci U S A. 2010;107:10926-31 pubmed publisher
Kang Y, Li Y, Dai C, Kiss L, Wu C, Liu Y. Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria. Kidney Int. 2010;78:363-73 pubmed publisher
Kauffman A, Ashraf J, Corces Zimmerman M, Landis J, Murphy C. Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age. PLoS Biol. 2010;8:e1000372 pubmed publisher
Kadandale P, Stender J, Glass C, Kiger A. Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment. Proc Natl Acad Sci U S A. 2010;107:10502-7 pubmed publisher
Heger P, Kroiher M, Ndifon N, Schierenberg E. Conservation of MAP kinase activity and MSP genes in parthenogenetic nematodes. BMC Dev Biol. 2010;10:51 pubmed publisher
Vrzal R, Gerbal Chaloin S, Maurel P, Dvorak Z. Comparative effects of microtubules disruption on glucocorticoid receptor functions in proliferating and quiescent cells. Int J Toxicol. 2010;29:326-35 pubmed publisher
Lee T, Lai T, Lin S, Wu C, Ni I, Yang Y, et al. The B56gamma3 regulatory subunit of protein phosphatase 2A (PP2A) regulates S phase-specific nuclear accumulation of PP2A and the G1 to S transition. J Biol Chem. 2010;285:21567-80 pubmed publisher
Chrétien M, Zhang M, Jackson M, Kapus A, Langille B. Mechanotransduction by endothelial cells is locally generated, direction-dependent, and ligand-specific. J Cell Physiol. 2010;224:352-61 pubmed publisher
Huang C, Li Y, Lopez A, Chiang C, Kaufman R, Snider M, et al. Temporal regulation of Cat-1 (cationic amino acid transporter-1) gene transcription during endoplasmic reticulum stress. Biochem J. 2010;429:215-24 pubmed publisher
Schaffer B, Park K, Yiu G, Conklin J, Lin C, Burkhart D, et al. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer Res. 2010;70:3877-83 pubmed publisher
Molvaersmyr A, Saether T, Gilfillan S, Lorenzo P, Kvaløy H, Matre V, et al. A SUMO-regulated activation function controls synergy of c-Myb through a repressor-activator switch leading to differential p300 recruitment. Nucleic Acids Res. 2010;38:4970-84 pubmed publisher
Dai C, Saleem M, Holzman L, Mathieson P, Liu Y. Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria. Kidney Int. 2010;77:962-73 pubmed publisher
Deidda G, Rossi N, Putti S, Tocchini Valentini G. ARCHAEA-ExPRESs targeting of alpha-tubulin 4 mRNA: a model for high-specificity trans-splicing. FASEB J. 2010;24:2976-84 pubmed publisher
LORENZO D, Li M, Mische S, Armbrust K, Ranum L, Hays T. Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila. J Cell Biol. 2010;189:143-58 pubmed publisher
Gokhin D, Lewis R, McKeown C, Nowak R, Kim N, Littlefield R, et al. Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology. J Cell Biol. 2010;189:95-109 pubmed publisher
Bryson P, Cho N, Einav S, Lee C, Tai V, Bechtel J, et al. A small molecule inhibits HCV replication and alters NS4B's subcellular distribution. Antiviral Res. 2010;87:1-8 pubmed publisher
Bee C, Moshnikova A, Mellor C, Molloy J, Koryakina Y, Stieglitz B, et al. Growth and tumor suppressor NORE1A is a regulatory node between Ras signaling and microtubule nucleation. J Biol Chem. 2010;285:16258-66 pubmed publisher
Saitoh Y, Martínez Bruyn V, Uota S, Hasegawa A, Yamamoto N, Imoto I, et al. Overexpression of NF-?B inducing kinase underlies constitutive NF-?B activation in lung cancer cells. Lung Cancer. 2010;70:263-70 pubmed publisher
Reo E, Seum C, Spierer P, Bontron S. Sumoylation of Drosophila SU(VAR)3-7 is required for its heterochromatic function. Nucleic Acids Res. 2010;38:4254-62 pubmed publisher
Alnagar F, Brennan P, Brewis I. Bicarbonate-dependent serine/threonine protein dephosphorylation in capacitating boar spermatozoa. J Androl. 2010;31:393-405 pubmed publisher
Li K, Zhu W, Zeng K, Zhang Z, Ye J, Ou W, et al. Proteome characterization of cassava (Manihot esculenta Crantz) somatic embryos, plantlets and tuberous roots. Proteome Sci. 2010;8:10 pubmed publisher
Cui P, Lee A, Zhou F, Murray M. Impaired transactivation of the human CYP2J2 arachidonic acid epoxygenase gene in HepG2 cells subjected to nitrative stress. Br J Pharmacol. 2010;159:1440-9 pubmed publisher
Aoyagi M, Gaspar M, Shenk T. Human cytomegalovirus UL69 protein facilitates translation by associating with the mRNA cap-binding complex and excluding 4EBP1. Proc Natl Acad Sci U S A. 2010;107:2640-5 pubmed publisher
Carracedo S, Lu N, Popova S, Jonsson R, Eckes B, Gullberg D. The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation. J Biol Chem. 2010;285:10434-45 pubmed publisher
Royer Pokora B, Busch M, Beier M, Duhme C, de Torres C, Mora J, et al. Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm. Hum Mol Genet. 2010;19:1651-68 pubmed publisher
Dulla K, Daub H, Hornberger R, Nigg E, Körner R. Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics. 2010;9:1167-81 pubmed publisher
Ohe M, Kawamura Y, Ueno H, Inoue D, Kanemori Y, Senoo C, et al. Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail. Mol Biol Cell. 2010;21:905-13 pubmed publisher
Bolhuis S, Richter Landsberg C. Effect of proteasome inhibition by MG-132 on HSP27 oligomerization, phosphorylation, and aggresome formation in the OLN-93 oligodendroglia cell line. J Neurochem. 2010;114:960-71 pubmed publisher
Sansam C, CRUZ N, Danielian P, Amsterdam A, Lau M, Hopkins N, et al. A vertebrate gene, ticrr, is an essential checkpoint and replication regulator. Genes Dev. 2010;24:183-94 pubmed publisher
Chazaud B. Dual effect of HGF on satellite/myogenic cell quiescence. Focus on "High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite c. Am J Physiol Cell Physiol. 2010;298:C448-9 pubmed publisher
Maj M, Gartner W, Ilhan A, Neziri D, Attems J, Wagner L. Expression of TAU in insulin-secreting cells and its interaction with the calcium-binding protein secretagogin. J Endocrinol. 2010;205:25-36 pubmed publisher
Madhavan R, Gong Z, Ma J, Chan A, Peng H. The function of cortactin in the clustering of acetylcholine receptors at the vertebrate neuromuscular junction. PLoS ONE. 2009;4:e8478 pubmed publisher
Yamada M, Tatsumi R, Yamanouchi K, Hosoyama T, Shiratsuchi S, Sato A, et al. High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo. Am J Physiol Cell Physiol. 2010;298:C465-76 pubmed publisher
Menzies F, Huebener J, Renna M, Bonin M, Riess O, Rubinsztein D. Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3. Brain. 2010;133:93-104 pubmed publisher
Luo Z, Wijeweera A, Oh Y, Liou Y, Melamed P. Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcription. Mol Cell Biol. 2010;30:745-63 pubmed publisher
Magnaghi V, Parducz A, Frasca A, Ballabio M, Procacci P, Racagni G, et al. GABA synthesis in Schwann cells is induced by the neuroactive steroid allopregnanolone. J Neurochem. 2010;112:980-90 pubmed publisher
Ngai S, Batty S, Liao K, Mogridge J. An anthrax lethal factor mutant that is defective at causing pyroptosis retains proapoptotic activity. FEBS J. 2010;277:119-27 pubmed publisher
Leivar P, Tepperman J, Monte E, Calderon R, Liu T, Quail P. Definition of early transcriptional circuitry involved in light-induced reversal of PIF-imposed repression of photomorphogenesis in young Arabidopsis seedlings. Plant Cell. 2009;21:3535-53 pubmed publisher
Reischauer S, Levesque M, NUSSLEIN VOLHARD C, Sonawane M. Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis. PLoS Genet. 2009;5:e1000720 pubmed publisher
Wiren K, Semirale A, Hashimoto J, Zhang X. Signaling pathways implicated in androgen regulation of endocortical bone. Bone. 2010;46:710-23 pubmed publisher
Khan M, Goila Gaur R, Kao S, Miyagi E, WALKER R, Strebel K. Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerization. Retrovirology. 2009;6:99 pubmed publisher
Schrötzlmair F, Kopitz C, Halbgewachs B, Lu F, Algül H, Brunner N, et al. Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by host-derived urokinase-type plasminogen activator. J Cell Mol Med. 2010;14:2760-70 pubmed publisher
Robinson J, Vanbrocklin M, Guilbeault A, Signorelli D, Brandner S, Holmen S. Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation. Oncogene. 2010;29:335-44 pubmed publisher
Dupraz S, Grassi D, Bernis M, Sosa L, Bisbal M, Gastaldi L, et al. The TC10-Exo70 complex is essential for membrane expansion and axonal specification in developing neurons. J Neurosci. 2009;29:13292-301 pubmed publisher
Ciro M, Prosperini E, Quarto M, Grazini U, Walfridsson J, McBlane F, et al. ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors. Cancer Res. 2009;69:8491-8 pubmed publisher
Khazaei M, Püschel A. Phosphorylation of the par polarity complex protein Par3 at serine 962 is mediated by aurora a and regulates its function in neuronal polarity. J Biol Chem. 2009;284:33571-9 pubmed publisher
Yeap L, Hayashi K, Surani M. ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage. Epigenetics Chromatin. 2009;2:12 pubmed publisher
Tiedemann K, Hussein O, Sadvakassova G, Guo Y, Siegel P, Komarova S. Breast cancer-derived factors stimulate osteoclastogenesis through the Ca2+/protein kinase C and transforming growth factor-beta/MAPK signaling pathways. J Biol Chem. 2009;284:33662-70 pubmed publisher
Meeh P, Farrell C, Croshaw R, Crimm H, Miller S, Oroian D, et al. A gene expression classifier of node-positive colorectal cancer. Neoplasia. 2009;11:1074-83 pubmed
Adzic M, Djordjevic A, Demonacos C, Krstic Demonacos M, Radojcic M. The role of phosphorylated glucocorticoid receptor in mitochondrial functions and apoptotic signalling in brain tissue of stressed Wistar rats. Int J Biochem Cell Biol. 2009;41:2181-8 pubmed publisher
Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stühler K, Meyer H, et al. Identification and functional characterization of microRNAs involved in the malignant progression of gliomas. Brain Pathol. 2010;20:539-50 pubmed publisher
Clark A, Sawyer G, Robertson S, Sutherland Smith A. Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders. Hum Mol Genet. 2009;18:4791-800 pubmed publisher
Ohnishi Y, Tokunaga K, Kaneko K, Hohjoh H. Assessment of allele-specific gene silencing by RNA interference with mutant and wild-type reporter alleles. J RNAi Gene Silencing. 2006;2:154-60 pubmed
Difilippantonio M, Ghadimi B, Howard T, Camps J, Nguyen Q, Ferris D, et al. Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells. Environ Mol Mutagen. 2009;50:672-96 pubmed publisher
Jensen P, Zheng X, Lee T, O Connor M. The Drosophila Activin-like ligand Dawdle signals preferentially through one isoform of the Type-I receptor Baboon. Mech Dev. 2009;126:950-7 pubmed publisher
Martin S, Okano S, Kistler C, Fernandez Rojo M, Hill M, Parton R. Spatiotemporal regulation of early lipolytic signaling in adipocytes. J Biol Chem. 2009;284:32097-107 pubmed publisher
Dorsett M, Schedl T. A role for dynein in the inhibition of germ cell proliferative fate. Mol Cell Biol. 2009;29:6128-39 pubmed publisher
Bocquet A, Berges R, Frank R, Robert P, Peterson A, Eyer J. Neurofilaments bind tubulin and modulate its polymerization. J Neurosci. 2009;29:11043-54 pubmed publisher
Kim J, Shin M, Song K, Park S. Evaluation of alpha-tubulin as an antigenic and molecular probe to detect Giardia lamblia. Korean J Parasitol. 2009;47:287-91 pubmed publisher
Silva G, Jeney V, Chora A, Larsen R, Balla J, Soares M. Oxidized hemoglobin is an endogenous proinflammatory agonist that targets vascular endothelial cells. J Biol Chem. 2009;284:29582-95 pubmed publisher
Bregeon J, Loirand G, Pacaud P, Rolli Derkinderen M. Angiotensin II induces RhoA activation through SHP2-dependent dephosphorylation of the RhoGAP p190A in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2009;297:C1062-70 pubmed publisher
Vogt A, McPherson P, Shen X, Balachandran R, Zhu G, Raccor B, et al. High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs. Chem Biol Drug Des. 2009;74:358-68 pubmed publisher
Wainman A, Buster D, Duncan T, Metz J, Ma A, Sharp D, et al. A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes. Genes Dev. 2009;23:1876-81 pubmed publisher
Glaschick S, Röcker C, Deuschle K, Wiedenmann J, Oswald F, Mailänder V, et al. Axial resolution enhancement by 4Pi confocal fluorescence microscopy with two-photon excitation. J Biol Phys. 2007;33:433-43 pubmed publisher
Shah A, Friedman M, Huang S, Roberts M, Li X, Li S. Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17. Hum Mol Genet. 2009;18:4141-52 pubmed publisher
Zhou K, Rolls M, Hall D, Malone C, Hanna Rose W. A ZYG-12-dynein interaction at the nuclear envelope defines cytoskeletal architecture in the C. elegans gonad. J Cell Biol. 2009;186:229-41 pubmed publisher
Sabherwal N, Tsutsui A, Hodge S, Wei J, Chalmers A, Papalopulu N. The apicobasal polarity kinase aPKC functions as a nuclear determinant and regulates cell proliferation and fate during Xenopus primary neurogenesis. Development. 2009;136:2767-77 pubmed publisher
Hsiao Y, Tong Z, Westfall J, Ault J, Page McCaw P, Ferland R. Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking. Hum Mol Genet. 2009;18:3926-41 pubmed publisher
Honma K, Tsuzuki S, Nakagawa M, Tagawa H, Nakamura S, Morishima Y, et al. TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas. Blood. 2009;114:2467-75 pubmed publisher
Hussain S, Benavente S, Nascimento E, Dragoni I, Kurowski A, Gillich A, et al. The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability. J Cell Biol. 2009;186:27-40 pubmed publisher
Gaspar Maia A, Alajem A, Polesso F, Sridharan R, Mason M, Heidersbach A, et al. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature. 2009;460:863-8 pubmed publisher
Crowe S, Wu L, Economou C, Turpin S, Matzaris M, Hoehn K, et al. Pigment epithelium-derived factor contributes to insulin resistance in obesity. Cell Metab. 2009;10:40-7 pubmed publisher
Lee J, Tattoli I, Wojtal K, Vavricka S, Philpott D, Girardin S. pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling. J Biol Chem. 2009;284:23818-29 pubmed publisher
Ushio K, Hashimoto T, Kitamura N, Tanaka T. Id1 is down-regulated by hepatocyte growth factor via ERK-dependent and ERK-independent signaling pathways, leading to increased expression of p16INK4a in hepatoma cells. Mol Cancer Res. 2009;7:1179-88 pubmed publisher
Wu Q, Bruce A, Jedrusik A, Ellis P, Andrews R, Langford C, et al. CARM1 is required in embryonic stem cells to maintain pluripotency and resist differentiation. Stem Cells. 2009;27:2637-2645 pubmed publisher
Lafarga V, Cuadrado A, Lopez de Silanes I, Bengoechea R, Fernandez Capetillo O, Nebreda A. p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint. Mol Cell Biol. 2009;29:4341-51 pubmed publisher
Wignall S, Villeneuve A. Lateral microtubule bundles promote chromosome alignment during acentrosomal oocyte meiosis. Nat Cell Biol. 2009;11:839-44 pubmed publisher
Mancini F, Di Conza G, Pellegrino M, Rinaldo C, Prodosmo A, Giglio S, et al. MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway. EMBO J. 2009;28:1926-39 pubmed publisher
Tatsumi R, Sankoda Y, Anderson J, Sato Y, Mizunoya W, Shimizu N, et al. Possible implication of satellite cells in regenerative motoneuritogenesis: HGF upregulates neural chemorepellent Sema3A during myogenic differentiation. Am J Physiol Cell Physiol. 2009;297:C238-52 pubmed publisher
Martinez Morales J, Rembold M, Greger K, Simpson J, Brown K, Quiring R, et al. ojoplano-mediated basal constriction is essential for optic cup morphogenesis. Development. 2009;136:2165-75 pubmed publisher
Sun L, Haun S, Jones R, Edmondson R, Machaca K. Kinase-dependent regulation of inositol 1,4,5-trisphosphate-dependent Ca2+ release during oocyte maturation. J Biol Chem. 2009;284:20184-96 pubmed publisher
Kingeter L, Schaefer B. Expanding the multicolor capabilities of basic confocal microscopes by employing red and near-infrared quantum dot conjugates. BMC Biotechnol. 2009;9:49 pubmed publisher
Sasazawa Y, Futamura Y, Tashiro E, Imoto M. Vacuolar H+-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway. Cancer Sci. 2009;100:1460-7 pubmed publisher
Satoh K, Nigro P, Matoba T, O Dell M, Cui Z, Shi X, et al. Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. Nat Med. 2009;15:649-56 pubmed publisher
Salvado M, Alfranca A, Escolano A, Haeggstrom J, Redondo J. COX-2 limits prostanoid production in activated HUVECs and is a source of PGH2 for transcellular metabolism to PGE2 by tumor cells. Arterioscler Thromb Vasc Biol. 2009;29:1131-7 pubmed publisher
Wittkopp N, Huntzinger E, Weiler C, Sauliere J, Schmidt S, Sonawane M, et al. Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival. Mol Cell Biol. 2009;29:3517-28 pubmed publisher
Haren L, Gnadt N, Wright M, Merdes A. NuMA is required for proper spindle assembly and chromosome alignment in prometaphase. BMC Res Notes. 2009;2:64 pubmed publisher
Wörter V, Schweigreiter R, Kinzel B, Mueller M, Barske C, Böck G, et al. Inhibitory activity of myelin-associated glycoprotein on sensory neurons is largely independent of NgR1 and NgR2 and resides within Ig-Like domains 4 and 5. PLoS ONE. 2009;4:e5218 pubmed publisher
Johnson J, Lu C, Raharjo E, McNally K, McNally F, Mains P. Levels of the ubiquitin ligase substrate adaptor MEL-26 are inversely correlated with MEI-1/katanin microtubule-severing activity during both meiosis and mitosis. Dev Biol. 2009;330:349-57 pubmed publisher
Marzesco A, Wilsch Bräuninger M, Dubreuil V, Janich P, Langenfeld K, Thiele C, et al. Release of extracellular membrane vesicles from microvilli of epithelial cells is enhanced by depleting membrane cholesterol. FEBS Lett. 2009;583:897-902 pubmed publisher
Demontis F, Dahmann C. Characterization of the Drosophila ortholog of the human Usher Syndrome type 1G protein sans. PLoS ONE. 2009;4:e4753 pubmed publisher
Amir S, Wang R, Simons J, Mabjeesh N. SEPT9_v1 up-regulates hypoxia-inducible factor 1 by preventing its RACK1-mediated degradation. J Biol Chem. 2009;284:11142-51 pubmed publisher
Vuong B, Lee M, Kabir S, Irimia C, Macchiarulo S, McKnight G, et al. Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination. Nat Immunol. 2009;10:420-6 pubmed publisher
Weidenfeld Baranboim K, Hasin T, Darlyuk I, Heinrich R, Elhanani O, Pan J, et al. The ubiquitously expressed bZIP inhibitor, JDP2, suppresses the transcription of its homologue immediate early gene counterpart, ATF3. Nucleic Acids Res. 2009;37:2194-203 pubmed publisher
Doonan F, Wallace D, O Driscoll C, Cotter T. Rosiglitazone acts as a neuroprotectant in retinal cells via up-regulation of sestrin-1 and SOD-2. J Neurochem. 2009;109:631-43 pubmed publisher
Jiang H, Wu J, He C, Yang W, Li H. Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation. Cell Res. 2009;19:458-68 pubmed publisher
Wang X, Yang P, Liu Z, Liu W, Hu Y, Chen H, et al. Exploring the mechanism of Physcomitrella patens desiccation tolerance through a proteomic strategy. Plant Physiol. 2009;149:1739-50 pubmed publisher
Takagi S, Simizu S, Osada H. RECK negatively regulates matrix metalloproteinase-9 transcription. Cancer Res. 2009;69:1502-8 pubmed publisher
Dohn M, Brown M, Reynolds A. An essential role for p120-catenin in Src- and Rac1-mediated anchorage-independent cell growth. J Cell Biol. 2009;184:437-50 pubmed publisher
Sánchez Cañete M, Carvalho L, Pérez Victoria F, Gamarro F, Castanys S. Low plasma membrane expression of the miltefosine transport complex renders Leishmania braziliensis refractory to the drug. Antimicrob Agents Chemother. 2009;53:1305-13 pubmed publisher
Liu J, Wu Z, Nizami Z, Deryusheva S, Rajendra T, Beumer K, et al. Coilin is essential for Cajal body organization in Drosophila melanogaster. Mol Biol Cell. 2009;20:1661-70 pubmed publisher
de Jesus Perez V, Alastalo T, Wu J, Axelrod J, Cooke J, Amieva M, et al. Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol. 2009;184:83-99 pubmed publisher
Naviaux R, Le T, Bedelbaeva K, Leferovich J, Gourevitch D, Sachadyn P, et al. Retained features of embryonic metabolism in the adult MRL mouse. Mol Genet Metab. 2009;96:133-44 pubmed publisher
Lewkowicz E, Herit F, Le Clainche C, Bourdoncle P, Perez F, Niedergang F. The microtubule-binding protein CLIP-170 coordinates mDia1 and actin reorganization during CR3-mediated phagocytosis. J Cell Biol. 2008;183:1287-98 pubmed publisher
Klapholz B, Dietrich B, Schaffner C, Heredia F, Quivy J, Almouzni G, et al. CAF-1 is required for efficient replication of euchromatic DNA in Drosophila larval endocycling cells. Chromosoma. 2009;118:235-48 pubmed publisher
Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, et al. 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse. Hum Mol Genet. 2009;18:898-910 pubmed publisher
Miller A, Bement W. Regulation of cytokinesis by Rho GTPase flux. Nat Cell Biol. 2009;11:71-7 pubmed publisher
Egea J, Erlacher C, Montanez E, Burtscher I, Yamagishi S, Hess M, et al. Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation. Genes Dev. 2008;22:3349-62 pubmed publisher
Omran H, Kobayashi D, Olbrich H, Tsukahara T, Loges N, Hagiwara H, et al. Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. Nature. 2008;456:611-6 pubmed publisher
Takahata M, Inoue Y, Tsuda H, Imoto I, Koinuma D, Hayashi M, et al. SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells. J Biol Chem. 2009;284:3334-44 pubmed publisher
Johansson J, Ericsson J, Janson J, Beraki S, Stanic D, Mandic S, et al. An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function. PLoS Genet. 2008;4:e1000278 pubmed publisher
Gardini A, Cesaroni M, Luzi L, Okumura A, Biggs J, Minardi S, et al. AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets. PLoS Genet. 2008;4:e1000275 pubmed publisher
Lagresle Peyrou C, Six E, Picard C, Rieux Laucat F, Michel V, Ditadi A, et al. Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness. Nat Genet. 2009;41:106-11 pubmed publisher
Liu N, Bezprozvannaya S, Williams A, Qi X, Richardson J, Bassel Duby R, et al. microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev. 2008;22:3242-54 pubmed publisher
Postberg J, Heyse K, Cremer M, Cremer T, Lipps H. Spatial and temporal plasticity of chromatin during programmed DNA-reorganization in Stylonychia macronuclear development. Epigenetics Chromatin. 2008;1:3 pubmed publisher
Liu F, Fu Y, Meyskens F. MiTF regulates cellular response to reactive oxygen species through transcriptional regulation of APE-1/Ref-1. J Invest Dermatol. 2009;129:422-31 pubmed publisher
Gonzalez Alvaro I, Ortiz A, Domínguez Jiménez C, Aragón Bodi A, Díaz Sánchez B, Sanchez Madrid F. Inhibition of tumour necrosis factor and IL-17 production by leflunomide involves the JAK/STAT pathway. Ann Rheum Dis. 2009;68:1644-50 pubmed publisher
Di Certo M, Batassa E, Casella I, Serafino A, Floridi A, Passananti C, et al. Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit. BMC Cell Biol. 2008;9:56 pubmed publisher
Ranganathan S, Harmison G, Meyertholen K, Pennuto M, Burnett B, Fischbeck K. Mitochondrial abnormalities in spinal and bulbar muscular atrophy. Hum Mol Genet. 2009;18:27-42 pubmed publisher
Venoux M, Delmouly K, Milhavet O, Vidal Eychenié S, Giorgi D, Rouquier S. Gene organization, evolution and expression of the microtubule-associated protein ASAP (MAP9). BMC Genomics. 2008;9:406 pubmed publisher
Mayanagi T, Morita T, Hayashi K, Fukumoto K, Sobue K. Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton. J Biol Chem. 2008;283:31183-96 pubmed publisher
Borlido J, Veltri G, Jackson A, Mills I. Clathrin is spindle-associated but not essential for mitosis. PLoS ONE. 2008;3:e3115 pubmed publisher
Perilhou A, Tourrel Cuzin C, Kharroubi I, Henique C, Fauveau V, Kitamura T, et al. The transcription factor COUP-TFII is negatively regulated by insulin and glucose via Foxo1- and ChREBP-controlled pathways. Mol Cell Biol. 2008;28:6568-79 pubmed publisher
Burkhart D, Viatour P, Ho V, Sage J. GFP reporter mice for the retinoblastoma-related cell cycle regulator p107. Cell Cycle. 2008;7:2544-52 pubmed
Rosser M, Grove D, Chen L, Cyr D. Assembly and misassembly of cystic fibrosis transmembrane conductance regulator: folding defects caused by deletion of F508 occur before and after the calnexin-dependent association of membrane spanning domain (MSD) 1 and MSD2. Mol Biol Cell. 2008;19:4570-9 pubmed publisher
Leal J, Ferrer I, Blanco Aparicio C, Hernandez Losa J, Ramon Y Cajal S, Carnero A, et al. S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesis. Carcinogenesis. 2008;29:2089-95 pubmed publisher
Moshnikova A, Kuznetsov S, Khokhlatchev A. Interaction of the growth and tumour suppressor NORE1A with microtubules is not required for its growth-suppressive function. BMC Res Notes. 2008;1:13 pubmed publisher
Tokumaru S, Suzuki M, Yamada H, Nagino M, Takahashi T. let-7 regulates Dicer expression and constitutes a negative feedback loop. Carcinogenesis. 2008;29:2073-7 pubmed publisher
Shtutman M, Chausovsky A, Prager Khoutorsky M, Schiefermeier N, Boguslavsky S, Kam Z, et al. Signaling function of alpha-catenin in microtubule regulation. Cell Cycle. 2008;7:2377-83 pubmed
Miyagi E, Schwartzkopff F, Plishka R, Buckler White A, Clouse K, Strebel K. APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages. Virology. 2008;379:266-74 pubmed publisher
Lee S, Feldman R, O Farrell P. An RNA interference screen identifies a novel regulator of target of rapamycin that mediates hypoxia suppression of translation in Drosophila S2 cells. Mol Biol Cell. 2008;19:4051-61 pubmed publisher
Hyenne V, Desrosiers M, Labbé J. C. elegans Brat homologs regulate PAR protein-dependent polarity and asymmetric cell division. Dev Biol. 2008;321:368-78 pubmed publisher
Storck S, Thiry M, Bouvet P. Conditional knockout of nucleolin in DT40 cells reveals the functional redundancy of its RNA-binding domains. Biol Cell. 2009;101:153-67 pubmed publisher
Tan S, Lyulcheva E, Dean J, Bennett D. Mars promotes dTACC dephosphorylation on mitotic spindles to ensure spindle stability. J Cell Biol. 2008;182:27-33 pubmed publisher
Umeyama T, Wang C. Polo-like kinase is expressed in S/G2/M phase and associated with the flagellum attachment zone in both procyclic and bloodstream forms of Trypanosoma brucei. Eukaryot Cell. 2008;7:1582-90 pubmed publisher
Wiren K, Semirale A, Zhang X, Woo A, Tommasini S, Price C, et al. Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis: a model for compartment-specific androgen action in the skeleton. Bone. 2008;43:440-51 pubmed publisher
Yin X, Cong X, Yan M, Zhang D. Deficiency of a potential 3p21.3 tumor suppressor gene UBE1L (UBA7) does not accelerate lung cancer development in K-rasLA2 mice. Lung Cancer. 2009;63:194-200 pubmed publisher
Latini F, Hemerly J, Oler G, Riggins G, Cerutti J. Re-expression of ABI3-binding protein suppresses thyroid tumor growth by promoting senescence and inhibiting invasion. Endocr Relat Cancer. 2008;15:787-99 pubmed publisher
Park T, Mitchell B, Abitua P, Kintner C, Wallingford J. Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat Genet. 2008;40:871-9 pubmed publisher
Li Y, Bevilacqua E, Chiribau C, Majumder M, Wang C, Croniger C, et al. Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during the . J Biol Chem. 2008;283:22443-56 pubmed publisher
Araki K, Kawauchi K, Tanaka N. IKK/NF-kappaB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors. Oncogene. 2008;27:5696-705 pubmed publisher
Schlichting K, Dahmann C. Hedgehog and Dpp signaling induce cadherin Cad86C expression in the morphogenetic furrow during Drosophila eye development. Mech Dev. 2008;125:712-28 pubmed publisher
Landshamer S, Hoehn M, Barth N, Duvezin Caubet S, Schwake G, Tobaben S, et al. Bid-induced release of AIF from mitochondria causes immediate neuronal cell death. Cell Death Differ. 2008;15:1553-63 pubmed publisher
Mi L, Xiao Z, Hood B, Dakshanamurthy S, Wang X, Govind S, et al. Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis. J Biol Chem. 2008;283:22136-46 pubmed publisher
Castro M, Leal J, Lleonart M, Ramon Y Cajal S, Carnero A. Loss-of-function genetic screening identifies a cluster of ribosomal proteins regulating p53 function. Carcinogenesis. 2008;29:1343-50 pubmed publisher
Strasser M, Mackenzie N, Dumstrei K, Nakkrasae L, Stebler J, Raz E. Control over the morphology and segregation of Zebrafish germ cell granules during embryonic development. BMC Dev Biol. 2008;8:58 pubmed publisher
Guo Y, Tiedemann K, Khalil J, Russo C, Siegel P, Komarova S. Osteoclast precursors acquire sensitivity to breast cancer derived factors early in differentiation. Bone. 2008;43:386-93 pubmed publisher
Lain S, Hollick J, Campbell J, Staples O, Higgins M, Aoubala M, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008;13:454-63 pubmed publisher
Spierer A, Begeot F, Spierer P, Delattre M. SU(VAR)3-7 links heterochromatin and dosage compensation in Drosophila. PLoS Genet. 2008;4:e1000066 pubmed publisher
Tegha Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, et al. EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase. J Cell Sci. 2008;121:1718-26 pubmed publisher
Benoit P, Papin C, Kwak J, Wickens M, Simonelig M. PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila. Development. 2008;135:1969-79 pubmed publisher
Hu C, Coughlin M, Field C, Mitchison T. Cell polarization during monopolar cytokinesis. J Cell Biol. 2008;181:195-202 pubmed publisher
Polager S, Ofir M, Ginsberg D. E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene. 2008;27:4860-4 pubmed publisher
Westbroek W, Tuchman M, Tinloy B, De Wever O, Vilboux T, Hertz J, et al. A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome. Mol Genet Metab. 2008;94:248-54 pubmed publisher
Kirstetter P, Schuster M, Bereshchenko O, Moore S, Dvinge H, Kurz E, et al. Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells. Cancer Cell. 2008;13:299-310 pubmed publisher
Yoshimura F, Luo X, Zhao X, Gerard H, Hudson A. Up-regulation of a cellular protein at the translational level by a retrovirus. Proc Natl Acad Sci U S A. 2008;105:5543-8 pubmed publisher
Yamamoto T, Lewellyn A, Maller J. Regulation of the Aurora B chromosome passenger protein complex during oocyte maturation in Xenopus laevis. Mol Cell Biol. 2008;28:4196-203 pubmed publisher
Bello V, Sirour C, Moreau N, Denker E, Darribère T. A function for dystroglycan in pronephros development in Xenopus laevis. Dev Biol. 2008;317:106-20 pubmed publisher
Zhang X, Goeres J, Zhang H, Yen T, Porter A, Matunis M. SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis. Mol Cell. 2008;29:729-41 pubmed publisher
Northey J, Chmielecki J, Ngan E, Russo C, Annis M, Muller W, et al. Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion. Mol Cell Biol. 2008;28:3162-76 pubmed publisher
Quadrini K, Gruzglin E, Bieker J. Non-random subcellular distribution of variant EKLF in erythroid cells. Exp Cell Res. 2008;314:1595-604 pubmed publisher
Budirahardja Y, GONCZY P. PLK-1 asymmetry contributes to asynchronous cell division of C. elegans embryos. Development. 2008;135:1303-13 pubmed publisher
Esposito C, D Alessio A, de Franciscis V, Cerchia L. A cross-talk between TrkB and Ret tyrosine kinases receptors mediates neuroblastoma cells differentiation. PLoS ONE. 2008;3:e1643 pubmed publisher
Ursini Siegel J, Hardy W, Zuo D, Lam S, Sanguin Gendreau V, Cardiff R, et al. ShcA signalling is essential for tumour progression in mouse models of human breast cancer. EMBO J. 2008;27:910-20 pubmed publisher
Buttrick G, Beaumont L, Leitch J, Yau C, Hughes J, Wakefield J. Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo. J Cell Biol. 2008;180:537-48 pubmed publisher
Gao S, Giansanti M, Buttrick G, Ramasubramanyan S, Auton A, Gatti M, et al. Australin: a chromosomal passenger protein required specifically for Drosophila melanogaster male meiosis. J Cell Biol. 2008;180:521-35 pubmed publisher
Pauli A, Althoff F, Oliveira R, Heidmann S, Schuldiner O, Lehner C, et al. Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Dev Cell. 2008;14:239-51 pubmed publisher
Rahman M, Davis S, Pumphrey J, Bao J, Nau M, Meltzer P, et al. TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype. Breast Cancer Res Treat. 2009;113:217-30 pubmed publisher
Vigneron A, Gamelin E, Coqueret O. The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition. Cancer Res. 2008;68:815-25 pubmed publisher
Dovedi S, Kirby J, Davies B, Leung H, Kelly J. Celecoxib has potent antitumour effects as a single agent and in combination with BCG immunotherapy in a model of urothelial cell carcinoma. Eur Urol. 2008;54:621-30 pubmed publisher
Patrakitkomjorn S, Kobayashi D, Morikawa T, Wilson M, Tsubota N, Irie A, et al. Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2. J Biol Chem. 2008;283:9399-413 pubmed publisher
Spiliotis E, Hunt S, Hu Q, Kinoshita M, Nelson W. Epithelial polarity requires septin coupling of vesicle transport to polyglutamylated microtubules. J Cell Biol. 2008;180:295-303 pubmed publisher
Castro M, Ferrer I, Cascon A, Guijarro M, Lleonart M, Ramon Y Cajal S, et al. PPP1CA contributes to the senescence program induced by oncogenic Ras. Carcinogenesis. 2008;29:491-9 pubmed publisher
Eguchi T, Kubota S, Kawata K, Mukudai Y, Uehara J, Ohgawara T, et al. Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene. Mol Cell Biol. 2008;28:2391-413 pubmed publisher
Hutt K, Shi Z, Albertini D, Petroff B. The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts morphogenesis of the rat pre-implantation embryo. BMC Dev Biol. 2008;8:1 pubmed publisher
Johnson C, Huang Y, Parrish A, Smith M, Vaughn A, Zhang Q, et al. Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues. Proc Natl Acad Sci U S A. 2007;104:20820-5 pubmed
Lundin V, Srayko M, Hyman A, Leroux M. Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans. Dev Biol. 2008;313:320-34 pubmed
Morita T, Mayanagi T, Sobue K. Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling. J Cell Biol. 2007;179:1027-42 pubmed
Cheng T, Hsiao Y, Lin C, Yu C, Hsu C, Chang M, et al. Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin. J Biol Chem. 2008;283:2454-64 pubmed
Singh S, Plassmeyer M, Gaur D, Miller L. Mononeme: a new secretory organelle in Plasmodium falciparum merozoites identified by localization of rhomboid-1 protease. Proc Natl Acad Sci U S A. 2007;104:20043-8 pubmed
Vauti F, Prochnow B, Freese E, Ramasamy S, Ruiz P, Arnold H. Arp3 is required during preimplantation development of the mouse embryo. FEBS Lett. 2007;581:5691-7 pubmed
Hattori T, Isobe T, Abe K, Kikuchi H, Kitagawa K, Oda T, et al. Pirh2 promotes ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1. Cancer Res. 2007;67:10789-95 pubmed
Kondo A, Hirayama N, Sugito Y, Shono M, Tanaka T, Kitamura N. Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation. J Biol Chem. 2008;283:1428-36 pubmed
Arts J, Angibaud P, Marien A, Floren W, Janssens B, King P, et al. R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies. Br J Cancer. 2007;97:1344-53 pubmed
Leal J, Fominaya J, Cascon A, Guijarro M, Blanco Aparicio C, Lleonart M, et al. Cellular senescence bypass screen identifies new putative tumor suppressor genes. Oncogene. 2008;27:1961-70 pubmed
Pesavento J, Yang H, Kelleher N, Mizzen C. Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle. Mol Cell Biol. 2008;28:468-86 pubmed
Peters N, Logan K, Miller A, Kropf D. Phospholipase D signaling regulates microtubule organization in the fucoid alga Silvetia compressa. Plant Cell Physiol. 2007;48:1764-74 pubmed
Bonnefoy E, Orsi G, Couble P, Loppin B. The essential role of Drosophila HIRA for de novo assembly of paternal chromatin at fertilization. PLoS Genet. 2007;3:1991-2006 pubmed
Graser S, Stierhof Y, Lavoie S, Gassner O, Lamla S, Le Clech M, et al. Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol. 2007;179:321-30 pubmed
Porter I, McClelland S, Khoudoli G, Hunter C, Andersen J, McAinsh A, et al. Bod1, a novel kinetochore protein required for chromosome biorientation. J Cell Biol. 2007;179:187-97 pubmed
Bentley A, Normand G, Hoyt J, King R. Distinct sequence elements of cyclin B1 promote localization to chromatin, centrosomes, and kinetochores during mitosis. Mol Biol Cell. 2007;18:4847-58 pubmed
Schaeper U, Vogel R, Chmielowiec J, Huelsken J, Rosario M, Birchmeier W. Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo. Proc Natl Acad Sci U S A. 2007;104:15376-81 pubmed
Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, et al. Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer. J Biol Chem. 2007;282:33681-90 pubmed
Stahl M, Retzlaff M, Nassal M, Beck J. Chaperone activation of the hepadnaviral reverse transcriptase for template RNA binding is established by the Hsp70 and stimulated by the Hsp90 system. Nucleic Acids Res. 2007;35:6124-36 pubmed
Crevel G, Hashimoto R, Vass S, Sherkow J, Yamaguchi M, Heck M, et al. Differential requirements for MCM proteins in DNA replication in Drosophila S2 cells. PLoS ONE. 2007;2:e833 pubmed
Suelves M, Vidal B, Serrano A, Tjwa M, Roma J, Lopez Alemany R, et al. uPA deficiency exacerbates muscular dystrophy in MDX mice. J Cell Biol. 2007;178:1039-51 pubmed
Corona D, Siriaco G, Armstrong J, Snarskaya N, McClymont S, Scott M, et al. ISWI regulates higher-order chromatin structure and histone H1 assembly in vivo. PLoS Biol. 2007;5:e232 pubmed
Puig O, Bragado Nilsson E, Koski T, Seraphin B. The U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and human. Nucleic Acids Res. 2007;35:5874-85 pubmed
Shynlova O, Tsui P, Dorogin A, Langille B, Lye S. The expression of transforming growth factor beta in pregnant rat myometrium is hormone and stretch dependent. Reproduction. 2007;134:503-11 pubmed
Burkel B, Von Dassow G, Bement W. Versatile fluorescent probes for actin filaments based on the actin-binding domain of utrophin. Cell Motil Cytoskeleton. 2007;64:822-32 pubmed
Lee H, Tsai J, Liao P, Tsai W, Lin K, Chuang C, et al. Glycogen synthase kinase 3 alpha and 3 beta have distinct functions during cardiogenesis of zebrafish embryo. BMC Dev Biol. 2007;7:93 pubmed
Hou S, Maccarana M, Min T, Strate I, Pera E. The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo. Dev Cell. 2007;13:226-41 pubmed
Schneider L, Essmann F, Kletke A, Rio P, Hanenberg H, Wetzel W, et al. The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival. J Biol Chem. 2007;282:29273-83 pubmed
Minami K, Tambe Y, Watanabe R, Isono T, Haneda M, Isobe K, et al. Suppression of viral replication by stress-inducible GADD34 protein via the mammalian serine/threonine protein kinase mTOR pathway. J Virol. 2007;81:11106-15 pubmed
Li Y, Dai C, Wu C, Liu Y. PINCH-1 promotes tubular epithelial-to-mesenchymal transition by interacting with integrin-linked kinase. J Am Soc Nephrol. 2007;18:2534-43 pubmed
Ursini Siegel J, Rajput A, Lu H, Sanguin Gendreau V, Zuo D, Papavasiliou V, et al. Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. Mol Cell Biol. 2007;27:6361-71 pubmed
Eisele Y, Baumann M, Klebl B, Nordhammer C, Jucker M, Kilger E. Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid-beta degrading enzyme neprilysin. Mol Biol Cell. 2007;18:3591-600 pubmed
Gadea G, de Toledo M, Anguille C, Roux P. Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices. J Cell Biol. 2007;178:23-30 pubmed
Griffis E, Stuurman N, Vale R. Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore. J Cell Biol. 2007;177:1005-15 pubmed
Chen L, Liu D, Songyang Z. Telomere maintenance through spatial control of telomeric proteins. Mol Cell Biol. 2007;27:5898-909 pubmed
Olguin H, Yang Z, Tapscott S, Olwin B. Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination. J Cell Biol. 2007;177:769-79 pubmed
Oh H, Jin X, Kim J, Oh M, Pian X, Kim J, et al. Characteristics of primary and immortalized fibroblast cells derived from the miniature and domestic pigs. BMC Cell Biol. 2007;8:20 pubmed
Kirchner J, Gross S, Bennett D, Alphey L. Essential, overlapping and redundant roles of the Drosophila protein phosphatase 1 alpha and 1 beta genes. Genetics. 2007;176:273-81 pubmed
Walshe J, Serewko Auret M, Teakle N, Cameron S, Minto K, Smith L, et al. Inactivation of glutathione peroxidase activity contributes to UV-induced squamous cell carcinoma formation. Cancer Res. 2007;67:4751-8 pubmed
Seum C, Reo E, Peng H, Rauscher F, Spierer P, Bontron S. Drosophila SETDB1 is required for chromosome 4 silencing. PLoS Genet. 2007;3:e76 pubmed
LU J, Qian J, Keppler D, Cardoso W. Cathespin H is an Fgf10 target involved in Bmp4 degradation during lung branching morphogenesis. J Biol Chem. 2007;282:22176-84 pubmed
Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanaka F, et al. CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model. J Neurosci. 2007;27:5115-26 pubmed
Goto K, Kamiya Y, Imamura T, Miyazono K, Miyazawa K. Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors. J Biol Chem. 2007;282:20603-11 pubmed
Sachdev P, Menon S, Kastner D, Chuang J, Yeh T, Conde C, et al. G protein beta gamma subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowth. EMBO J. 2007;26:2621-32 pubmed
Zhang D, Rogers G, Buster D, Sharp D. Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes. J Cell Biol. 2007;177:231-42 pubmed
Grammont M. Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis. J Cell Biol. 2007;177:139-50 pubmed
Harrison M, Lu X, Horvitz H. LIN-61, one of two Caenorhabditis elegans malignant-brain-tumor-repeat-containing proteins, acts with the DRM and NuRD-like protein complexes in vulval development but not in certain other biological processes. Genetics. 2007;176:255-71 pubmed
Buttner E, Gil Krzewska A, Rajpurohit A, Hunter C. Progression from mitotic catastrophe to germ cell death in Caenorhabditis elegans lis-1 mutants requires the spindle checkpoint. Dev Biol. 2007;305:397-410 pubmed
Ikenouchi J, Umeda K, Tsukita S, Furuse M, Tsukita S. Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization. J Cell Biol. 2007;176:779-86 pubmed
Kim H, Takahashi M, Matsuo K, Ono Y. Recruitment of CG-NAP to the Golgi apparatus through interaction with dynein-dynactin complex. Genes Cells. 2007;12:421-34 pubmed
Young J, Bromberg White J, Zylstra C, Church J, Boguslawski E, Resau J, et al. LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin. PLoS Pathog. 2007;3:e27 pubmed
You B, Ren A, Yan G, Sun J. Activation of sphingosine kinase-1 mediates inhibition of vascular smooth muscle cell apoptosis by hyperglycemia. Diabetes. 2007;56:1445-53 pubmed
Lo K, Kogoy J, Pfister K. The DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3. J Biol Chem. 2007;282:11205-12 pubmed
Sharma V, Litersky J, Bhaskar K, Lee G. Tau impacts on growth-factor-stimulated actin remodeling. J Cell Sci. 2007;120:748-57 pubmed
Dumont J, Petri S, Pellegrin F, Terret M, Bohnsack M, Rassinier P, et al. A centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytes. J Cell Biol. 2007;176:295-305 pubmed
Calella A, Nerlov C, Lopez R, Sciarretta C, Von Bohlen Und Halbach O, Bereshchenko O, et al. Neurotrophin/Trk receptor signaling mediates C/EBPalpha, -beta and NeuroD recruitment to immediate-early gene promoters in neuronal cells and requires C/EBPs to induce immediate-early gene transcription. Neural Dev. 2007;2:4 pubmed
Dikovskaya D, Schiffmann D, Newton I, Oakley A, Kroboth K, Sansom O, et al. Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. J Cell Biol. 2007;176:183-95 pubmed
Burwell E, McCarty G, Simpson L, Thompson K, Loeb D. Isoforms of Wilms' tumor suppressor gene (WT1) have distinct effects on mammary epithelial cells. Oncogene. 2007;26:3423-30 pubmed
Szebenyi G, Hall B, Yu R, Hashim A, KRAMER H. Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function. Traffic. 2007;8:32-46 pubmed
Reis Filho J, Simpson P, Turner N, Lambros M, Jones C, Mackay A, et al. FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clin Cancer Res. 2006;12:6652-62 pubmed
Rojas R, Kametaka S, Haft C, Bonifacino J. Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. Mol Cell Biol. 2007;27:1112-24 pubmed
King M, Kan H, Baas P, Erisir A, Glabe C, Bloom G. Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid. J Cell Biol. 2006;175:541-6 pubmed
Park S, Tournell C, Sinjoanu R, Ferreira A. Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons. Neuroscience. 2007;144:119-27 pubmed
Nagata M, Goto K, Ehata S, Kobayashi N, Saitoh M, Miyoshi H, et al. Nuclear and cytoplasmic c-Ski differently modulate cellular functions. Genes Cells. 2006;11:1267-80 pubmed
Kamath K, Okouneva T, Larson G, Panda D, Wilson L, Jordan M. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules. Mol Cancer Ther. 2006;5:2225-33 pubmed
Tan R, Zhang J, Tan X, Zhang X, Yang J, Liu Y. Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation. J Am Soc Nephrol. 2006;17:2781-91 pubmed
Strauss B, Adams R, Papalopulu N. A default mechanism of spindle orientation based on cell shape is sufficient to generate cell fate diversity in polarised Xenopus blastomeres. Development. 2006;133:3883-93 pubmed
Wright K, Vaughn A, Deshmukh M. Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons. Cell Death Differ. 2007;14:625-33 pubmed
Vigneron A, Cherier J, Barré B, Gamelin E, Coqueret O. The cell cycle inhibitor p21waf1 binds to the myc and cdc25A promoters upon DNA damage and induces transcriptional repression. J Biol Chem. 2006;281:34742-50 pubmed
Sands W, Woolson H, Milne G, Rutherford C, Palmer T. Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells. Mol Cell Biol. 2006;26:6333-46 pubmed
Reverte C, Benware A, Jones C, LaFlamme S. Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis. J Cell Biol. 2006;174:491-7 pubmed
Wood J, Landers J, Bingley M, McDermott C, Thomas McArthur V, Gleadall L, et al. The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo. Hum Mol Genet. 2006;15:2763-71 pubmed
Surace E, Strickland A, Hess R, Gutmann D, Naughton C. Tslc1 (nectin-like molecule-2) is essential for spermatozoa motility and male fertility. J Androl. 2006;27:816-25 pubmed
Sales V, Engelmayr G, Mettler B, Johnson J, Sacks M, Mayer J. Transforming growth factor-beta1 modulates extracellular matrix production, proliferation, and apoptosis of endothelial progenitor cells in tissue-engineering scaffolds. Circulation. 2006;114:I193-9 pubmed
Basto R, Lau J, Vinogradova T, Gardiol A, Woods C, Khodjakov A, et al. Flies without centrioles. Cell. 2006;125:1375-86 pubmed
Yasuor H, Abu Abied M, Belausov E, Madmony A, Sadot E, Riov J, et al. Glyphosate-induced anther indehiscence in cotton is partially temperature dependent and involves cytoskeleton and secondary wall modifications and auxin accumulation. Plant Physiol. 2006;141:1306-15 pubmed
Rabe B, Glebe D, Kann M. Lipid-mediated introduction of hepatitis B virus capsids into nonsusceptible cells allows highly efficient replication and facilitates the study of early infection events. J Virol. 2006;80:5465-73 pubmed
Klein U, Nigg E, Gruneberg U. Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol Biol Cell. 2006;17:2547-58 pubmed
Ribbeck K, Groen A, Santarella R, Bohnsack M, Raemaekers T, Kocher T, et al. NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell. 2006;17:2646-60 pubmed
Radhakrishnan S, Gartel A. A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity. Cancer Res. 2006;66:3264-70 pubmed
Kock N, Naismith T, Boston H, Ozelius L, Corey D, Breakefield X, et al. Effects of genetic variations in the dystonia protein torsinA: identification of polymorphism at residue 216 as protein modifier. Hum Mol Genet. 2006;15:1355-64 pubmed
McCue S, Dajnowiec D, Xu F, Zhang M, Jackson M, Langille B. Shear stress regulates forward and reverse planar cell polarity of vascular endothelium in vivo and in vitro. Circ Res. 2006;98:939-46 pubmed
Schlichting K, Wilsch Bräuninger M, Demontis F, Dahmann C. Cadherin Cad99C is required for normal microvilli morphology in Drosophila follicle cells. J Cell Sci. 2006;119:1184-95 pubmed
Levy J, Sumner C, Caviston J, Tokito M, Ranganathan S, Ligon L, et al. A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation. J Cell Biol. 2006;172:733-45 pubmed
Varma D, Dujardin D, Stehman S, Vallee R. Role of the kinetochore/cell cycle checkpoint protein ZW10 in interphase cytoplasmic dynein function. J Cell Biol. 2006;172:655-62 pubmed
Ong S, Hsu H, Liu H, Chu C, Tai J. Multifarious transcriptional regulation of adhesion protein gene ap65-1 by a novel Myb1 protein in the protozoan parasite Trichomonas vaginalis. Eukaryot Cell. 2006;5:391-9 pubmed
Chattopadhyay S, Machado Pinilla R, Manguan Garcia C, Belda Iniesta C, Moratilla C, Cejas P, et al. MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-small-cell lung cancer. Oncogene. 2006;25:3335-45 pubmed
Gruneberg U, Neef R, Li X, Chan E, Chalamalasetty R, Nigg E, et al. KIF14 and citron kinase act together to promote efficient cytokinesis. J Cell Biol. 2006;172:363-72 pubmed
Servert P, Garcia Castro J, Díaz V, Lucas D, Gonzalez M, Martinez A C, et al. Inducible model for beta-six-mediated site-specific recombination in mammalian cells. Nucleic Acids Res. 2006;34:e1 pubmed
Gebhardt A, Frye M, Herold S, Benitah S, Braun K, Samans B, et al. Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. J Cell Biol. 2006;172:139-49 pubmed
Tang C, Lin C, Tang T. Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis. Dev Biol. 2006;290:398-410 pubmed
Hoberg J, Popko A, Ramsey C, Mayo M. IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300. Mol Cell Biol. 2006;26:457-71 pubmed
Matter C, Wyss M, Meier P, Späth N, von Lukowicz T, Lohmann C, et al. 18F-choline images murine atherosclerotic plaques ex vivo. Arterioscler Thromb Vasc Biol. 2006;26:584-9 pubmed
Manna T, Thrower D, Miller H, Curmi P, Wilson L. Stathmin strongly increases the minus end catastrophe frequency and induces rapid treadmilling of bovine brain microtubules at steady state in vitro. J Biol Chem. 2006;281:2071-8 pubmed
Reilein A, Yamada S, Nelson W. Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells. J Cell Biol. 2005;171:845-55 pubmed
Cullen C, Brittle A, Ito T, Ohkura H. The conserved kinase NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster. J Cell Biol. 2005;171:593-602 pubmed
Kawaguchi Y, Ito A, Appella E, Yao T. Charge modification at multiple C-terminal lysine residues regulates p53 oligomerization and its nucleus-cytoplasm trafficking. J Biol Chem. 2006;281:1394-400 pubmed
Dobenecker M, Schmedt C, Okada M, Tarakhovsky A. The ubiquitously expressed Csk adaptor protein Cbp is dispensable for embryogenesis and T-cell development and function. Mol Cell Biol. 2005;25:10533-42 pubmed
Bompard G, Sharp S, Freiss G, Machesky L. Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B. J Cell Sci. 2005;118:5393-403 pubmed
Brown C, Maier K, Stauber T, Ginkel L, Wordeman L, Vernos I, et al. Kinesin-2 is a motor for late endosomes and lysosomes. Traffic. 2005;6:1114-24 pubmed
Harris S, Gil G, Robins H, Hu W, Hirshfield K, Bond E, et al. Detection of functional single-nucleotide polymorphisms that affect apoptosis. Proc Natl Acad Sci U S A. 2005;102:16297-302 pubmed
Goshima G, Nedelec F, Vale R. Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins. J Cell Biol. 2005;171:229-40 pubmed
Martin S, Driessen K, Nixon S, Zerial M, Parton R. Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism. J Biol Chem. 2005;280:42325-35 pubmed
Vigneron A, Roninson I, Gamelin E, Coqueret O. Src inhibits adriamycin-induced senescence and G2 checkpoint arrest by blocking the induction of p21waf1. Cancer Res. 2005;65:8927-35 pubmed
Penman G, Leung L, Nathke I. The adenomatous polyposis coli protein (APC) exists in two distinct soluble complexes with different functions. J Cell Sci. 2005;118:4741-50 pubmed
Sarkar S, Floto R, Berger Z, Imarisio S, Cordenier A, Pasco M, et al. Lithium induces autophagy by inhibiting inositol monophosphatase. J Cell Biol. 2005;170:1101-11 pubmed
Barros T, Kinoshita K, Hyman A, Raff J. Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. J Cell Biol. 2005;170:1039-46 pubmed
Peset I, Seiler J, Sardon T, Bejarano L, Rybina S, Vernos I. Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis. J Cell Biol. 2005;170:1057-66 pubmed
Kinoshita K, Noetzel T, Pelletier L, Mechtler K, Drechsel D, Schwager A, et al. Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol. 2005;170:1047-55 pubmed
Vent J, Wyatt T, Smith D, Banerjee A, Luduena R, Sisson J, et al. Direct involvement of the isotype-specific C-terminus of beta tubulin in ciliary beating. J Cell Sci. 2005;118:4333-41 pubmed
Eash S, Atwood W. Involvement of cytoskeletal components in BK virus infectious entry. J Virol. 2005;79:11734-41 pubmed
Tudor E, Perkinton M, Schmidt A, Ackerley S, Brownlees J, Jacobsen N, et al. ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth. J Biol Chem. 2005;280:34735-40 pubmed
Laurino L, Wang X, de la Houssaye B, Sosa L, Dupraz S, Caceres A, et al. PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone. J Cell Sci. 2005;118:3653-62 pubmed
Campaner S, Kaldis P, Izraeli S, Kirsch I. Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint. Mol Cell Biol. 2005;25:6660-72 pubmed
Berryman S, Clark S, Monaghan P, Jackson T. Early events in integrin alphavbeta6-mediated cell entry of foot-and-mouth disease virus. J Virol. 2005;79:8519-34 pubmed
Royle S, Bright N, Lagnado L. Clathrin is required for the function of the mitotic spindle. Nature. 2005;434:1152-7 pubmed
Shim K, Minowada G, Coling D, Martin G. Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. Dev Cell. 2005;8:553-64 pubmed
Bernot K, Lee C, Coulombe P. A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability. J Cell Biol. 2005;168:965-74 pubmed
Cavalli V, Kujala P, Klumperman J, Goldstein L. Sunday Driver links axonal transport to damage signaling. J Cell Biol. 2005;168:775-87 pubmed
Schlichting K, Demontis F, Dahmann C. Cadherin Cad99C is regulated by Hedgehog signaling in Drosophila. Dev Biol. 2005;279:142-54 pubmed
Barré B, Vigneron A, Coqueret O. The STAT3 transcription factor is a target for the Myc and riboblastoma proteins on the Cdc25A promoter. J Biol Chem. 2005;280:15673-81 pubmed
Nishimura T, Takahashi M, Kim H, Mukai H, Ono Y. Centrosome-targeting region of CG-NAP causes centrosome amplification by recruiting cyclin E-cdk2 complex. Genes Cells. 2005;10:75-86 pubmed
Rommelfanger K, Weinshenker D, Miller G. Reduced MPTP toxicity in noradrenaline transporter knockout mice. J Neurochem. 2004;91:1116-24 pubmed
Preuss M, Kovar D, Lee Y, Staiger C, Delmer D, Liu B. A plant-specific kinesin binds to actin microfilaments and interacts with cortical microtubules in cotton fibers. Plant Physiol. 2004;136:3945-55 pubmed publisher
Bishop J, Han Z, Schumacher J. The Caenorhabditis elegans Aurora B kinase AIR-2 phosphorylates and is required for the localization of a BimC kinesin to meiotic and mitotic spindles. Mol Biol Cell. 2005;16:742-56 pubmed
Boggio R, Colombo R, Hay R, Draetta G, Chiocca S. A mechanism for inhibiting the SUMO pathway. Mol Cell. 2004;16:549-61 pubmed
Schmidt K, Nichols B. Functional interdependence between septin and actin cytoskeleton. BMC Cell Biol. 2004;5:43 pubmed
Miyazaki H, Watabe T, Kitamura T, Miyazono K. BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells. Oncogene. 2004;23:9326-35 pubmed
Young J, Stauber T, del Nery E, Vernos I, Pepperkok R, Nilsson T. Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'. Mol Biol Cell. 2005;16:162-77 pubmed
Giuliano K, Chen Y, Taylor D. High-content screening with siRNA optimizes a cell biological approach to drug discovery: defining the role of P53 activation in the cellular response to anticancer drugs. J Biomol Screen. 2004;9:557-68 pubmed
Mandelkow E, Thies E, Trinczek B, Biernat J, Mandelkow E. MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons. J Cell Biol. 2004;167:99-110 pubmed
Huh M, Parker M, Scime A, Parks R, Rudnicki M. Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation. J Cell Biol. 2004;166:865-76 pubmed
Gaetz J, Kapoor T. Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles. J Cell Biol. 2004;166:465-71 pubmed
Giraud S, Hurlstone A, Avril S, Coqueret O. Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene. Oncogene. 2004;23:7391-8 pubmed
Hayashi K, Shibata K, Morita T, Iwasaki K, Watanabe M, Sobue K. Insulin receptor substrate-1/SHP-2 interaction, a phenotype-dependent switching machinery of insulin-like growth factor-I signaling in vascular smooth muscle cells. J Biol Chem. 2004;279:40807-18 pubmed
Gwynn B, Martina J, Bonifacino J, Sviderskaya E, Lamoreux M, Bennett D, et al. Reduced pigmentation (rp), a mouse model of Hermansky-Pudlak syndrome, encodes a novel component of the BLOC-1 complex. Blood. 2004;104:3181-9 pubmed
Gruneberg U, Neef R, Honda R, Nigg E, Barr F. Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. J Cell Biol. 2004;166:167-72 pubmed
Le Cam L, Lacroix M, Ciemerych M, Sardet C, Sicinski P. The E4F protein is required for mitotic progression during embryonic cell cycles. Mol Cell Biol. 2004;24:6467-75 pubmed
Hill C, Anway M, Zirkin B, Brown T. Intratesticular androgen levels, androgen receptor localization, and androgen receptor expression in adult rat Sertoli cells. Biol Reprod. 2004;71:1348-58 pubmed
Martinez Campos M, Basto R, Baker J, Kernan M, Raff J. The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis. J Cell Biol. 2004;165:673-83 pubmed
Seale P, Ishibashi J, Scime A, Rudnicki M. Pax7 is necessary and sufficient for the myogenic specification of CD45+:Sca1+ stem cells from injured muscle. PLoS Biol. 2004;2:E130 pubmed
Arighi C, Hartnell L, Aguilar R, Haft C, Bonifacino J. Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol. 2004;165:123-33 pubmed
Sun L, Machaca K. Ca(2+)(cyt) negatively regulates the initiation of oocyte maturation. J Cell Biol. 2004;165:63-75 pubmed
Perkinton M, Standen C, Lau K, Kesavapany S, Byers H, Ward M, et al. The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling. J Biol Chem. 2004;279:22084-91 pubmed
Mariner D, Davis M, Reynolds A. EGFR signaling to p120-catenin through phosphorylation at Y228. J Cell Sci. 2004;117:1339-50 pubmed
Izumi Y, Ohta N, Itoh Furuya A, Fuse N, Matsuzaki F. Differential functions of G protein and Baz-aPKC signaling pathways in Drosophila neuroblast asymmetric division. J Cell Biol. 2004;164:729-38 pubmed
Klausen P, Bjerregaard M, Borregaard N, Cowland J. End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6. J Leukoc Biol. 2004;75:569-78 pubmed
Stark A, Brennecke J, Russell R, Cohen S. Identification of Drosophila MicroRNA targets. PLoS Biol. 2003;1:E60 pubmed
Dujardin D, Barnhart L, Stehman S, Gomes E, Gundersen G, Vallee R. A role for cytoplasmic dynein and LIS1 in directed cell movement. J Cell Biol. 2003;163:1205-11 pubmed
Rao M, Campbell J, Yuan A, Kumar A, Gotow T, Uchiyama Y, et al. The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate. J Cell Biol. 2003;163:1021-31 pubmed
Batonnet S, Leibovitch M, Tintignac L, Leibovitch S. Critical role for lysine 133 in the nuclear ubiquitin-mediated degradation of MyoD. J Biol Chem. 2004;279:5413-20 pubmed
Day R, Gupta J, MacRae T. A small heat shock/alpha-crystallin protein from encysted Artemia embryos suppresses tubulin denaturation. Cell Stress Chaperones. 2003;8:183-93 pubmed
Dalal S, Rosser M, Cyr D, Hanson P. Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway. Mol Biol Cell. 2004;15:637-48 pubmed
Davis M, Ireton R, Reynolds A. A core function for p120-catenin in cadherin turnover. J Cell Biol. 2003;163:525-34 pubmed
Anilkumar N, Parsons M, Monk R, Ng T, Adams J. Interaction of fascin and protein kinase Calpha: a novel intersection in cell adhesion and motility. EMBO J. 2003;22:5390-402 pubmed
Taverna S, Ghersi G, Ginestra A, Rigogliuso S, Pecorella S, Alaimo G, et al. Shedding of membrane vesicles mediates fibroblast growth factor-2 release from cells. J Biol Chem. 2003;278:51911-9 pubmed
Nakata T, Hirokawa N. Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head. J Cell Biol. 2003;162:1045-55 pubmed
Rehm M, Dussmann H, Prehn J. Real-time single cell analysis of Smac/DIABLO release during apoptosis. J Cell Biol. 2003;162:1031-43 pubmed
Goshima G, Vale R. The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line. J Cell Biol. 2003;162:1003-16 pubmed
Show M, Anway M, Folmer J, Zirkin B. Reduced intratesticular testosterone concentration alters the polymerization state of the Sertoli cell intermediate filament cytoskeleton by degradation of vimentin. Endocrinology. 2003;144:5530-6 pubmed
Raemaekers T, Ribbeck K, Beaudouin J, Annaert W, van Camp M, Stockmans I, et al. NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization. J Cell Biol. 2003;162:1017-29 pubmed
Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg E, Mayer T, et al. Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J Cell Biol. 2003;162:863-75 pubmed
Wright A, Hunter C. Mutations in a beta-tubulin disrupt spindle orientation and microtubule dynamics in the early Caenorhabditis elegans embryo. Mol Biol Cell. 2003;14:4512-25 pubmed
Yu F, Cai Y, Kaushik R, Yang X, Chia W. Distinct roles of Galphai and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions. J Cell Biol. 2003;162:623-33 pubmed
Kawasaki K, Smith R, Hsieh C, Sun J, Chao J, Liao J. Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis. Mol Cell Biol. 2003;23:5726-37 pubmed
Siegel P, Shu W, Massague J. Mad upregulation and Id2 repression accompany transforming growth factor (TGF)-beta-mediated epithelial cell growth suppression. J Biol Chem. 2003;278:35444-50 pubmed
Lichtenstein N, Geiger B, Kam Z. Quantitative analysis of cytoskeletal organization by digital fluorescent microscopy. Cytometry A. 2003;54:8-18 pubmed
Popova J, Rasenick M. G beta gamma mediates the interplay between tubulin dimers and microtubules in the modulation of Gq signaling. J Biol Chem. 2003;278:34299-308 pubmed
Lallemand D, Curto M, Saotome I, Giovannini M, McClatchey A. NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions. Genes Dev. 2003;17:1090-100 pubmed
Xia C, Roberts E, Her L, Liu X, Williams D, Cleveland D, et al. Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol. 2003;161:55-66 pubmed
Aumais J, Williams S, Luo W, Nishino M, Caldwell K, Caldwell G, et al. Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis. J Cell Sci. 2003;116:1991-2003 pubmed
Breckenridge D, Stojanovic M, Marcellus R, Shore G. Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol. 2003;160:1115-27 pubmed
Mayo M, Denlinger C, Broad R, Yeung F, Reilly E, Shi Y, et al. Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway. J Biol Chem. 2003;278:18980-9 pubmed
Rosin Arbesfeld R, Cliffe A, Brabletz T, Bienz M. Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription. EMBO J. 2003;22:1101-13 pubmed
Khodjakov A, Copenagle L, Gordon M, Compton D, Kapoor T. Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis. J Cell Biol. 2003;160:671-83 pubmed
Kotlo K, Yehiely F, Efimova E, Harasty H, Hesabi B, Shchors K, et al. Nrf2 is an inhibitor of the Fas pathway as identified by Achilles' Heel Method, a new function-based approach to gene identification in human cells. Oncogene. 2003;22:797-806 pubmed
Nicholas B, Smethurst P, Verderio E, Jones R, Griffin M. Cross-linking of cellular proteins by tissue transglutaminase during necrotic cell death: a mechanism for maintaining tissue integrity. Biochem J. 2003;371:413-22 pubmed
Rivera C, Li H, Thomas Crusells J, Lahtinen H, Viitanen T, Nanobashvili A, et al. BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion. J Cell Biol. 2002;159:747-52 pubmed
Esposito C, Marra M, Giuberti G, D Alessandro A, Porta R, Cozzolino A, et al. Ubiquitination of tissue transglutaminase is modulated by interferon alpha in human lung cancer cells. Biochem J. 2003;370:205-12 pubmed
McDonald H, Helfant A, Mahony E, Khosla S, Goetsch L. Mutational analysis reveals a role for the C terminus of the proteasome subunit Rpt4p in spindle pole body duplication in Saccharomyces cerevisiae. Genetics. 2002;162:705-20 pubmed
Quintyne N, Schroer T. Distinct cell cycle-dependent roles for dynactin and dynein at centrosomes. J Cell Biol. 2002;159:245-54 pubmed
Shang Y, Li B, Gorovsky M. Tetrahymena thermophila contains a conventional gamma-tubulin that is differentially required for the maintenance of different microtubule-organizing centers. J Cell Biol. 2002;158:1195-206 pubmed
Rusan N, Tulu U, Fagerstrom C, Wadsworth P. Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport. J Cell Biol. 2002;158:997-1003 pubmed
Gruneberg U, Glotzer M, Gartner A, Nigg E. The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. J Cell Biol. 2002;158:901-14 pubmed
Manabe N, Hirai S, Imai F, Nakanishi H, Takai Y, Ohno S. Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells. Dev Dyn. 2002;225:61-9 pubmed
Malminen M, Peltonen S, Koivunen J, Peltonen J. Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis. BMC Dermatol. 2002;2:10 pubmed
Rao M, Garcia M, Miyazaki Y, Gotow T, Yuan A, Mattina S, et al. Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport. J Cell Biol. 2002;158:681-93 pubmed
Zhou J, Gupta K, Yao J, Ye K, Panda D, Giannakakou P, et al. Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine. J Biol Chem. 2002;277:39777-85 pubmed
Harada A, Teng J, Takei Y, Oguchi K, Hirokawa N. MAP2 is required for dendrite elongation, PKA anchoring in dendrites, and proper PKA signal transduction. J Cell Biol. 2002;158:541-9 pubmed
Ramirez de Molina A, Gutierrez R, Ramos M, Silva J, Silva J, Bonilla F, et al. Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy. Oncogene. 2002;21:4317-22 pubmed
Hubbert C, Guardiola A, Shao R, Kawaguchi Y, Ito A, Nixon A, et al. HDAC6 is a microtubule-associated deacetylase. Nature. 2002;417:455-8 pubmed
Rapoport M, Dawson H, Binder L, Vitek M, Ferreira A. Tau is essential to beta -amyloid-induced neurotoxicity. Proc Natl Acad Sci U S A. 2002;99:6364-9 pubmed
Stamer K, Vogel R, Thies E, Mandelkow E, Mandelkow E. Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol. 2002;156:1051-63 pubmed
Vidal A, Millard S, Miller J, Koff A. Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status. J Biol Chem. 2002;277:16433-40 pubmed
Brunet A, Kanai F, Stehn J, Xu J, Sarbassova D, Frangioni J, et al. 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport. J Cell Biol. 2002;156:817-28 pubmed
Mayo M, Madrid L, Westerheide S, Jones D, Yuan X, Baldwin A, et al. PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit. J Biol Chem. 2002;277:11116-25 pubmed
Howell B, McEwen B, Canman J, Hoffman D, Farrar E, Rieder C, et al. Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J Cell Biol. 2001;155:1159-72 pubmed
Hannak E, Kirkham M, Hyman A, Oegema K. Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. J Cell Biol. 2001;155:1109-16 pubmed
Akari H, Bour S, Kao S, Adachi A, Strebel K. The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors. J Exp Med. 2001;194:1299-311 pubmed
Robertson J, Beaulieu J, Doroudchi M, Durham H, Julien J, Mushynski W. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. J Cell Biol. 2001;155:217-26 pubmed
Flusberg D, Numaguchi Y, Ingber D. Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells. Mol Biol Cell. 2001;12:3087-94 pubmed
Specht C, Schoepfer R. Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice. BMC Neurosci. 2001;2:11 pubmed
O BRIEN V, Grindlay G, Campo M. Cell transformation by the E5/E8 protein of bovine papillomavirus type 4. p27(Kip1), Elevated through increased protein synthesis is sequestered by cyclin D1-CDK4 complexes. J Biol Chem. 2001;276:33861-8 pubmed
Wakefield J, Bonaccorsi S, Gatti M. The drosophila protein asp is involved in microtubule organization during spindle formation and cytokinesis. J Cell Biol. 2001;153:637-48 pubmed
Bui N, Livolsi A, Peyron J, Prehn J. Activation of nuclear factor kappaB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IkappaBalpha. J Cell Biol. 2001;152:753-64 pubmed
Kabir N, Schaefer A, Nakhost A, Sossin W, Forscher P. Protein kinase C activation promotes microtubule advance in neuronal growth cones by increasing average microtubule growth lifetimes. J Cell Biol. 2001;152:1033-44 pubmed
Golden A, Sadler P, Wallenfang M, Schumacher J, Hamill D, Bates G, et al. Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans. J Cell Biol. 2000;151:1469-82 pubmed
Berger M, Vogt Sionov R, Levine A, Haupt Y. A role for the polyproline domain of p53 in its regulation by Mdm2. J Biol Chem. 2001;276:3785-90 pubmed
Rasmussen T, Mastrangelo M, Eden A, Pehrson J, Jaenisch R. Dynamic relocalization of histone MacroH2A1 from centrosomes to inactive X chromosomes during X inactivation. J Cell Biol. 2000;150:1189-98 pubmed
Rogers G, Chui K, Lee E, Wedaman K, Sharp D, Holland G, et al. A kinesin-related protein, KRP(180), positions prometaphase spindle poles during early sea urchin embryonic cell division. J Cell Biol. 2000;150:499-512 pubmed
Millard S, Vidal A, Markus M, Koff A. A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA. Mol Cell Biol. 2000;20:5947-59 pubmed
Ackerley S, Grierson A, Brownlees J, Thornhill P, Anderton B, Leigh P, et al. Glutamate slows axonal transport of neurofilaments in transfected neurons. J Cell Biol. 2000;150:165-76 pubmed
Yucel J, Marszalek J, McIntosh J, Goldstein L, Cleveland D, Philp A. CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. J Cell Biol. 2000;150:1-11 pubmed
Merdes A, Heald R, Samejima K, Earnshaw W, Cleveland D. Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. J Cell Biol. 2000;149:851-62 pubmed
Dreier L, Rapoport T. In vitro formation of the endoplasmic reticulum occurs independently of microtubules by a controlled fusion reaction. J Cell Biol. 2000;148:883-98 pubmed
Mimori Kiyosue Y, Shiina N, Tsukita S. Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells. J Cell Biol. 2000;148:505-18 pubmed
Lorson M, Horvitz H, van den Heuvel S. LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans. J Cell Biol. 2000;148:73-86 pubmed
Susa M, Marre R. Legionella pneumophila invasion of MRC-5 cells induces tyrosine protein phosphorylation. Infect Immun. 1999;67:4490-8 pubmed
Zhang C, Lee M, Chen A, Brown S, Hsieh T. Isolation and characterization of a Drosophila gene essential for early embryonic development and formation of cortical cleavage furrows. J Cell Biol. 1996;134:923-34 pubmed
product information
Product No. :
T9026
Product Name :
Monoclonal Anti-α-Tubulin antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
DM1A
Applications/Description :
Suitable for indirect immunofluorescence: 1:500 using cultured chicken fibroblasts; western blot: 1:500 using human or chicken fibroblasts
Species Reactivity :
bovine, rat, yeast, human, mouse, chicken, fungi, amphibian
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA