This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Thioridazine hydrochloride
catalog :
T9025
citations: 17
Reference
Lin C, Tan X, Chen M, Kusi M, Hung C, Chou C, et al. ERα-related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer. BMC Med Genomics. 2020;13:69 pubmed publisher
Ohshima M, Kamei S, Fushimi H, Mima S, Yamada T, Yamamoto T. Prediction of Drug Permeability Using In Vitro Blood-Brain Barrier Models with Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells. Biores Open Access. 2019;8:200-209 pubmed publisher
Yen C, Chen L, Li C, Chen S, Chua W, Lin Y, et al. Identification of phenothiazine as an ETV1‑targeting agent in gastrointestinal stromal tumors using the Connectivity Map. Int J Oncol. 2019;55:536-546 pubmed publisher
Denis K, Le Bris M, Le Guennec L, Barnier J, Faure C, Gouge A, et al. Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease. Nat Microbiol. 2019;4:972-984 pubmed publisher
Pala F, Di Girolamo D, Mella S, Yennek S, Chatre L, Ricchetti M, et al. Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis. J Cell Sci. 2018;131: pubmed publisher
Stenger M, Hendel K, Bollen P, Licht P, Kolmos H, Klitgaard J. Assessments of Thioridazine as a Helper Compound to Dicloxacillin against Methicillin-Resistant Staphylococcus aureus: In Vivo Trials in a Mouse Peritonitis Model. PLoS ONE. 2015;10:e0135571 pubmed publisher
Otręba M, Beberok A, Wrześniok D, Rok J, Buszman E. Effect of thioridazine on antioxidant status of HEMn-DP melanocytes. Naunyn Schmiedebergs Arch Pharmacol. 2015;388:1097-104 pubmed publisher
Singh A, Sharma S. Chemotherapeutic efficacy of thioridazine as an adjunct drug in a murine model of latent tuberculosis. Tuberculosis (Edinb). 2014;94:695-700 pubmed publisher
Kratz J, Schuster D, Edtbauer M, Saxena P, Mair C, Kirchebner J, et al. Experimentally validated HERG pharmacophore models as cardiotoxicity prediction tools. J Chem Inf Model. 2014;54:2887-901 pubmed publisher
Ohshima S, Seyama A. Establishment of proliferative tetraploid cells from normal human fibroblasts. Front Oncol. 2013;3:198 pubmed publisher
Ohshima S. Centrosome aberrations associated with cellular senescence and p53 localization at supernumerary centrosomes. Oxid Med Cell Longev. 2012;2012:217594 pubmed publisher
Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Shin J, Soukhova N, Flockhart D. Effect of antipsychotic drugs on human liver cytochrome P-450 (CYP) isoforms in vitro: preferential inhibition of CYP2D6. Drug Metab Dispos. 1999;27:1078-84 pubmed
Ashkenazy Shahar M, Beitner R. Effects of Ca(2+)-ionophore A23187 and calmodulin antagonists on regulatory mechanisms of glycolysis and cell viability of NIH-3T3 fibroblasts. Mol Genet Metab. 1999;67:334-42 pubmed
Someren J, Faber L, Klein J, Tumlin J. Heat shock proteins 70 and 90 increase calcineurin activity in vitro through calmodulin-dependent and independent mechanisms. Biochem Biophys Res Commun. 1999;260:619-25 pubmed
Crewe H, Lennard M, Tucker G, Woods F, Haddock R. The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes. Br J Clin Pharmacol. 1992;34:262-5 pubmed
product information
Catalog Number :
T9025
Product Name :
Thioridazine hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥99%
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA