product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-Tyrosine Hydroxylase antibody produced in rabbit
catalog :
T8700
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 30
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Grünewald A, Rygiel K, Hepplewhite P, Morris C, Picard M, Turnbull D. Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons. Ann Neurol. 2016;79:366-78 pubmed publisher
Bhat S, Ganesh C. Domperidone treatment attenuates stress-induced suppression of reproduction in viviparous mosquitofish Gambusia affinis. J Fish Biol. 2020;96:37-48 pubmed publisher
Wang Q, Zhang Y, Wang M, Song W, Shen Q, McKenzie A, et al. The landscape of multiscale transcriptomic networks and key regulators in Parkinson's disease. Nat Commun. 2019;10:5234 pubmed publisher
Voronin M, Kadnikov I, Voronkov D, Seredenin S. Chaperone Sigma1R mediates the neuroprotective action of afobazole in the 6-OHDA model of Parkinson's disease. Sci Rep. 2019;9:17020 pubmed publisher
Sande Melón M, Marques I, Galardi Castilla M, Langa X, Pérez López M, Botos M, et al. Adult sox10+ Cardiomyocytes Contribute to Myocardial Regeneration in the Zebrafish. Cell Rep. 2019;29:1041-1054.e5 pubmed publisher
Li C, Tsuang Y, Tsai T. Neuroprotective Effect of Schisandra Chinensis on Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Parkinsonian Syndrome in C57BL/6 Mice. Nutrients. 2019;11: pubmed publisher
Sun Q, Li X, Ren M, Zhao M, Zhong Q, Ren Y, et al. A whole-brain map of long-range inputs to GABAergic interneurons in the mouse medial prefrontal cortex. Nat Neurosci. 2019;22:1357-1370 pubmed publisher
Rizzi G, Tan K. Synergistic Nigral Output Pathways Shape Movement. Cell Rep. 2019;27:2184-2198.e4 pubmed publisher
Gumbs M, Vuuregge A, Eggels L, Unmehopa U, Lamuadni K, Mul J, et al. Afferent neuropeptide Y projections to the ventral tegmental area in normal-weight male Wistar rats. J Comp Neurol. 2019;527:2659-2674 pubmed publisher
Xue X, Zhang W, Zhu J, Chen X, Zhou S, Xu Z, et al. Aquaporin-4 deficiency reduces TGF-β1 in mouse midbrains and exacerbates pathology in experimental Parkinson's disease. J Cell Mol Med. 2019;23:2568-2582 pubmed publisher
García Domínguez I, Veselá K, García Revilla J, Carrillo Jimenez A, Roca Ceballos M, Santiago M, et al. Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson's Disease. Front Cell Neurosci. 2018;12:398 pubmed publisher
Kim B, Mitrofanis J, Stone J, Johnstone D. Remote tissue conditioning is neuroprotective against MPTP insult in mice. IBRO Rep. 2018;4:14-17 pubmed publisher
Ouyang Z, Li H, Zhang M, Xie S, Cheng L. Differential Innervation of Secretory Coils and Ducts in Human Eccrine Sweat Glands. Chin Med J (Engl). 2018;131:1964-1968 pubmed publisher
Kojima R, Bojar D, Rizzi G, Hamri G, El Baba M, Saxena P, et al. Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson's disease treatment. Nat Commun. 2018;9:1305 pubmed publisher
El Massri N, Weinrich T, Kam J, Jeffery G, Mitrofanis J. Photobiomodulation reduces gliosis in the basal ganglia of aged mice. Neurobiol Aging. 2018;66:131-137 pubmed publisher
Wang R, Zhao X, Xu J, Wen Y, Li A, Lu M, et al. Astrocytic JWA deletion exacerbates dopaminergic neurodegeneration by decreasing glutamate transporters in mice. Cell Death Dis. 2018;9:352 pubmed publisher
Diao H, Xue Y, Han X, Wang S, Liu C, Chen W, et al. Adenosine A2A Receptor Modulates the Activity of Globus Pallidus Neurons in Rats. Front Physiol. 2017;8:897 pubmed publisher
Jiang T, Long B, Gong H, Xu T, Li X, Duan Z, et al. A platform for efficient identification of molecular phenotypes of brain-wide neural circuits. Sci Rep. 2017;7:13891 pubmed publisher
Salkov V, Khudoerkov R, Voronkov D, Sobolev V, Kutukova K. [Morphochemical changes in the substantia nigra cellular structures in Parkinson's disease]. Arkh Patol. 2017;79:3-9 pubmed publisher
Bhatnagar M, Goel I, Roy T, Shukla S, Khurana S. Complete Comparison Display (CCD) evaluation of ethanol extracts of Centella asiatica and Withania somnifera shows that they can non-synergistically ameliorate biochemical and behavioural damages in MPTP induced Parkinson's model of mice. PLoS ONE. 2017;12:e0177254 pubmed publisher
Wang Y, Zhao W, Li G, Chen J, Guan X, Chen X, et al. Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease. PPAR Res. 2017;2017:4089214 pubmed publisher
Meng F, Wang J, Ding F, Xie Y, Zhang Y, Zhu J. Neuroprotective effect of matrine on MPTP-induced Parkinson's disease and on Nrf2 expression. Oncol Lett. 2017;13:296-300 pubmed publisher
Tekin I, Carkaci Salli N, Lewis M, Mailman R, Huang X, Vrana K. The V81M variant of tyrosine hydroxylase is associated with more severe freezing of gait in Parkinson's disease. Parkinsonism Relat Disord. 2016;23:86-90 pubmed publisher
Cui Q, Li X, Zhu H. Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway. Mol Med Rep. 2016;13:1381-8 pubmed publisher
Reinhart F, Massri N, Chabrol C, Cretallaz C, Johnstone D, Torres N, et al. Intracranial application of near-infrared light in a hemi-parkinsonian rat model: the impact on behavior and cell survival. J Neurosurg. 2016;124:1829-41 pubmed publisher
Fernández Santiago R, Carballo Carbajal I, Castellano G, Torrent R, Richaud Y, Sánchez Danés A, et al. Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients. EMBO Mol Med. 2015;7:1529-46 pubmed publisher
Darlot F, Moro C, El Massri N, Chabrol C, Johnstone D, Reinhart F, et al. Near-infrared light is neuroprotective in a monkey model of Parkinson disease. Ann Neurol. 2016;79:59-75 pubmed publisher
Jallah Z, Liang R, Feola A, Barone W, Palcsey S, Abramowitch S, et al. The impact of prolapse mesh on vaginal smooth muscle structure and function. BJOG. 2016;123:1076-85 pubmed publisher
Jennings K, Platt N, Cragg S. The impact of a parkinsonian lesion on dynamic striatal dopamine transmission depends on nicotinic receptor activation. Neurobiol Dis. 2015;82:262-268 pubmed publisher
Stayte S, Rentsch P, Li K, Vissel B. Activin A protects midbrain neurons in the 6-hydroxydopamine mouse model of Parkinson's disease. PLoS ONE. 2015;10:e0124325 pubmed publisher
product information
Product No. :
T8700
Product Name :
Anti-Tyrosine Hydroxylase antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for immunohistochemistry (frozen sections): 1:1,000; western blot: 1:1,000 using rat brain lysates of PC-12 cells stimulated by okadaic acid; indirect immunofluorescence: 1:1,000
Species Reactivity :
mammals
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA