product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-TGN46 antibody produced in rabbit
catalog :
T7576
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 20
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:300; loading ...; fig s4i
Gut G, Herrmann M, Pelkmans L. Multiplexed protein maps link subcellular organization to cellular states. Science. 2018;361: pubmed publisher
  • immunohistochemistry; human; 1:1000; loading ...; fig s3a
Hernandez Tiedra S, Fabrias G, Davila D, Salanueva I, Casas J, Montes L, et al. Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. Autophagy. 2016;12:2213-2229 pubmed
  • immunoprecipitation; human; fig 6d
Mkhikian H, Mortales C, Zhou R, Khachikyan K, Wu G, Haslam S, et al. Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. elife. 2016;5: pubmed publisher
Li S, Bronnimann M, Williams S, Campos S. Glutathione contributes to efficient post-Golgi trafficking of incoming HPV16 genome. PLoS ONE. 2019;14:e0225496 pubmed publisher
Shiraishi T, Sakaitani M, Otsuguro S, Maenaka K, Suzuki T, Nakaya T. Novel Notch signaling inhibitor NSI‑1 suppresses nuclear translocation of the Notch intracellular domain. Int J Mol Med. 2019;44:1574-1584 pubmed publisher
Hasegawa H. Simultaneous induction of distinct protein phase separation events in multiple subcellular compartments of a single cell. Exp Cell Res. 2019;379:92-109 pubmed publisher
Ishikawa K, Saiki S, Furuya N, Imamichi Y, Tsuboi Y, Hattori N. p150glued deficiency impairs effective fusion between autophagosomes and lysosomes due to their redistribution to the cell periphery. Neurosci Lett. 2019;690:181-187 pubmed publisher
Macdonald E, Brown L, Selvais A, Liu H, WARING T, Newman D, et al. HRS-WASH axis governs actin-mediated endosomal recycling and cell invasion. J Cell Biol. 2018;217:2549-2564 pubmed publisher
George J, Yan I, Patel T. Nanovesicle-mediated delivery of anticancer agents effectively induced cell death and regressed intrahepatic tumors in athymic mice. Lab Invest. 2018;98:895-910 pubmed publisher
Pekkonen P, Alve S, Balistreri G, Gramolelli S, Tatti Bugaeva O, Paatero I, et al. Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation. elife. 2018;7: pubmed publisher
Miller H, Larson C, Heinzen R. Actin polymerization in the endosomal pathway, but not on the Coxiella-containing vacuole, is essential for pathogen growth. PLoS Pathog. 2018;14:e1007005 pubmed publisher
Dietz A, Villinger C, Becker S, Frick M, von Einem J. A Tyrosine-Based Trafficking Motif of the Tegument Protein pUL71 Is Crucial for Human Cytomegalovirus Secondary Envelopment. J Virol. 2018;92: pubmed publisher
Al Akhrass H, Naves T, Vincent F, Magnaudeix A, Durand K, Bertin F, et al. Sortilin limits EGFR signaling by promoting its internalization in lung cancer. Nat Commun. 2017;8:1182 pubmed publisher
Battisti F, Napoletano C, Rahimi Koshkaki H, Belleudi F, Zizzari I, Ruscito I, et al. Tumor-Derived Microvesicles Modulate Antigen Cross-Processing via Reactive Oxygen Species-Mediated Alkalinization of Phagosomal Compartment in Dendritic Cells. Front Immunol. 2017;8:1179 pubmed publisher
Calton C, Bronnimann M, Manson A, Li S, Chapman J, Suarez Berumen M, et al. Translocation of the papillomavirus L2/vDNA complex across the limiting membrane requires the onset of mitosis. PLoS Pathog. 2017;13:e1006200 pubmed publisher
Dong N, Niu M, Hu L, Yao Q, Zhou R, Shao F. Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector. Nat Microbiol. 2016;2:16236 pubmed publisher
Li J, Chen Z, Stang M, Gao W. Transiently expressed ATG16L1 inhibits autophagosome biogenesis and aberrantly targets RAB11-positive recycling endosomes. Autophagy. 2017;13:345-358 pubmed publisher
Chen Y, Xia Z, Wang L, Yu Y, Liu P, Song E, et al. An efficient two-step subcellular fractionation method for the enrichment of insulin granules from INS-1 cells. Biophys Rep. 2015;1:34-40 pubmed publisher
Schmidt W, Rutledge S, Schüle R, Mayerhofer B, Züchner S, Boltshauser E, et al. Disruptive SCYL1 Mutations Underlie a Syndrome Characterized by Recurrent Episodes of Liver Failure, Peripheral Neuropathy, Cerebellar Atrophy, and Ataxia. Am J Hum Genet. 2015;97:855-61 pubmed publisher
Fuse A, Furuya N, Kakuta S, Inose A, Sato M, Koike M, et al. VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process. FEBS Lett. 2015;589:1430-6 pubmed publisher
product information
Product No. :
T7576
Product Name :
Anti-TGN46 antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for immunoprecipitation (IP): 10-20 μg using TGN46 from human HepG2 cell lysates.; western blot (chemiluminescent): 0.25-0.5 μg/mL using extracts of human HEK-293T cells expressing recombinant human TGN46; indirect immunofluorescence: 5-10 μg/mL using human A54
Species Reactivity :
human
Concentration :
~1 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA