product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Acetylated Tubulin antibody produced in mouse
catalog :
T7451
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6-11B-1
reactivity :
African green monkey, Atlantic halibut, marine lamprey, Octopus bimaculoides, Crepidula fornicata, , freshwater planarian, Common quail, human, mouse, rat, dogs, chicken, bovine, pigs , zebrafish , fruit fly , domestic sheep, Xenopus laevis, roundworm
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 844
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 3i
Xu P, Borges R, Fillatre J, de Oliveira Melo M, Cheng T, Thisse B, et al. Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre. Nat Commun. 2021;12:3277 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 2b
Grunddal K, Tonack S, Egerod K, Thompson J, Petersen N, Engelstoft M, et al. Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells. Mol Metab. 2021;51:101231 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 4h
Samuel R, Majd H, Richter M, Ghazizadeh Z, Zekavat S, Navickas A, et al. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Cell Stem Cell. 2020;27:876-889.e12 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 2a
Magupalli V, Negro R, Tian Y, Hauenstein A, Di Caprio G, Skillern W, et al. HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 2020;369: pubmed publisher
  • immunocytochemistry; mouse; 1:2000; loading ...; fig 4a
Yoshida S, Aoki K, Fujiwara K, Nakakura T, Kawamura A, Yamada K, et al. The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6a
Menendez L, Trecek T, Gopalakrishnan S, Tao L, Markowitz A, Yu H, et al. Generation of inner ear hair cells by direct lineage conversion of primary somatic cells. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:6000; loading ...; fig 1e
Di Matteo F, Pipicelli F, Kyrousi C, Tovecci I, Penna E, Crispino M, et al. Cystatin B is essential for proliferation and interneuron migration in individuals with EPM1 epilepsy. EMBO Mol Med. 2020;12:e11419 pubmed publisher
  • immunohistochemistry; roundworm ; 5 ug/ml; loading ...; fig 11b
Yu C, Barry N, Wassie A, Sinha A, Bhattacharya A, Asano S, et al. Expansion microscopy of C. elegans. elife. 2020;9: pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 5c
Wang X, Xie W, Yao Y, Zhu Y, Zhou J, Cui Y, et al. The heat shock protein family gene Hspa1l in male mice is dispensable for fertility. Peerj. 2020;8:e8702 pubmed publisher
  • immunocytochemistry; rat; 1:400; loading ...; fig 2a
Cao Y, Lipka J, Stucchi R, Burute M, Pan X, Portegies S, et al. Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Curr Biol. 2020;30:899-908.e6 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:500; loading ...; fig 1c
Hu C, Wang W, Brind Amour J, Singh P, Reeves G, Lorincz M, et al. Vertebrate diapause preserves organisms long term through Polycomb complex members. Science. 2020;367:870-874 pubmed publisher
  • immunohistochemistry; Xenopus laevis; 1:500; loading ...; fig 4n
Herrera Rincon C, Pare J, Martyniuk C, Jannetty S, Harrison C, Fischer A, et al. An in vivo brain-bacteria interface: the developing brain as a key regulator of innate immunity. NPJ Regen Med. 2020;5:2 pubmed publisher
  • immunohistochemistry; mouse; 1:700; loading ...; fig 1k
Wang L, Xie J, Zhang H, Tsang L, Tsang S, Braune E, et al. Notch signalling regulates epibranchial placode patterning and segregation. Development. 2020;147: pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig s2d
Boukhalfa A, Nascimbeni A, Ramel D, Dupont N, Hirsch E, Gayral S, et al. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nat Commun. 2020;11:294 pubmed publisher
  • immunohistochemistry; fruit fly ; 1:15,000; loading ...; fig 2g
  • western blot; mouse; loading ...; fig 3c
Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn Ng I, et al. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Sci Adv. 2019;5:eaax2705 pubmed publisher
  • immunocytochemistry; mouse; 1:10,000; loading ...; fig 1a
  • immunohistochemistry; mouse; 1:10,000; loading ...; fig s4
Martin Hurtado A, Martin Morales R, Robledinos Antón N, Blanco R, Palacios Blanco I, Lastres Becker I, et al. NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling. Sci Rep. 2019;9:13896 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 5c
Ombrato L, Nolan E, Kurelac I, Mavousian A, Bridgeman V, Heinze I, et al. Metastatic-niche labelling reveals parenchymal cells with stem features. Nature. 2019;572:603-608 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:1000; loading ...; fig 3s1b
Lekk I, Duboc V, Faro A, Nicolaou S, Blader P, Wilson S. Sox1a mediates the ability of the parapineal to impart habenular left-right asymmetry. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 6a
Dorsch L, Schuldt M, dos Remedios C, Schinkel A, de Jong P, Michels M, et al. Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy. Cells. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1c
Henriques T, Agostinelli E, Hernandez Clavijo A, Maurya D, Rock J, Harfe B, et al. TMEM16A calcium-activated chloride currents in supporting cells of the mouse olfactory epithelium. J Gen Physiol. 2019;: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s5g
A M, Fung T, Kettenbach A, Chakrabarti R, Higgs H. A complex containing lysine-acetylated actin inhibits the formin INF2. Nat Cell Biol. 2019;21:592-602 pubmed publisher
  • immunocytochemistry; rat; loading ...; fig 7a
Farías G, Fréal A, Tortosa E, Stucchi R, Pan X, Portegies S, et al. Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity. Neuron. 2019;102:184-201.e8 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1d
Rangel L, Bernabé Rubio M, Fernández Barrera J, Casares Arias J, Millan J, Alonso M, et al. Caveolin-1α regulates primary cilium length by controlling RhoA GTPase activity. Sci Rep. 2019;9:1116 pubmed publisher
  • immunohistochemistry; human; 1:2000; fig 2e
Shen Y, Zhang F, Li F, Jiang X, Yang Y, Li X, et al. Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella. Nat Commun. 2019;10:433 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 2a, 1b
Huang N, Zhang D, Li F, Chai P, Wang S, Teng J, et al. M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole. Nat Commun. 2018;9:4511 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4b
Pellegrini L, Hauser D, Li Y, Mamais A, Beilina A, Kumaran R, et al. Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice. Hum Mol Genet. 2018;27:3257-3271 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3d
Vidovic D, Davila R, Gronostajski R, Harvey T, Piper M. Transcriptional regulation of ependymal cell maturation within the postnatal brain. Neural Dev. 2018;13:2 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6c
Imtiaz A, Belyantseva I, Beirl A, Fenollar Ferrer C, Bashir R, Bukhari I, et al. CDC14A phosphatase is essential for hearing and male fertility in mouse and human. Hum Mol Genet. 2018;27:780-798 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 3a
Krey J, Dumont R, Wilmarth P, David L, Johnson K, Barr Gillespie P. ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells. J Neurosci. 2018;38:843-857 pubmed publisher
  • western blot; mouse; 1:50,000; loading ...; fig 1a
Qu X, Yuan F, Corona C, Pasini S, Pero M, Gundersen G, et al. Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity. J Cell Biol. 2017;216:3161-3178 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3i
He H, Huang M, Sun S, Wu Y, Lin X. Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development. PLoS Genet. 2017;13:e1006992 pubmed publisher
  • immunohistochemistry; Xenopus laevis; 1:2000; fig 2c
Toriyama M, Toriyama M, Wallingford J, Finnell R. Folate-dependent methylation of septins governs ciliogenesis during neural tube closure. FASEB J. 2017;31:3622-3635 pubmed publisher
  • immunocytochemistry; mouse; 1:50,000; loading ...; fig 3
  • immunocytochemistry; human; 1:50,000; loading ...; fig 3
Hua K, Ferland R. Fixation methods can differentially affect ciliary protein immunolabeling. Cilia. 2017;6:5 pubmed publisher
  • immunohistochemistry; marine lamprey; 1:500; loading ...; fig 1c
Green S, Uy B, Bronner M. Ancient evolutionary origin of vertebrate enteric neurons from trunk-derived neural crest. Nature. 2017;544:88-91 pubmed publisher
  • immunocytochemistry; mouse; 1:5000; loading ...; fig 2c
Yasuda K, Clatterbuck Soper S, Jackrel M, Shorter J, Mili S. FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination. J Cell Biol. 2017;216:1015-1034 pubmed publisher
  • flow cytometry; human; fig 1c
Weeden C, Chen Y, Ma S, Hu Y, Ramm G, Sutherland K, et al. Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway. PLoS Biol. 2017;15:e2000731 pubmed publisher
  • immunocytochemistry; human; 1:10,000; loading ...; fig 3a
Macia M, Halbritter J, Delous M, Bredrup C, Gutter A, Filhol E, et al. Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis. Am J Hum Genet. 2017;100:323-333 pubmed publisher
  • immunohistochemistry; Common quail; 1:1000; loading ...; fig 7
Matsubara Y, Nakano M, Kawamura K, Tsudzuki M, Funahashi J, Agata K, et al. Inactivation of Sonic Hedgehog Signaling and Polydactyly in Limbs of Hereditary Multiple Malformation, a Novel Type of Talpid Mutant. Front Cell Dev Biol. 2016;4:149 pubmed publisher
  • immunohistochemistry; mouse; 1:20,000; loading ...; fig 5b
Kaliszewski M, Kennedy A, Blaes S, Shaffer R, Knott A, Song W, et al. SOD1 Lysine 123 Acetylation in the Adult Central Nervous System. Front Cell Neurosci. 2016;10:287 pubmed publisher
  • immunohistochemistry; fruit fly ; fig 3f
Takács Z, Jankovics F, Vilmos P, Lenart P, Röper K, Erdelyi M. The spectraplakin Short stop is an essential microtubule regulator involved in epithelial closure in Drosophila. J Cell Sci. 2017;130:712-724 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 4a'
Hirano T, Katoh Y, Nakayama K. Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors. Mol Biol Cell. 2017;28:429-439 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 4b
Ho Y, Zhou L, Tam K, Too H. Enhanced non-viral gene delivery by coordinated endosomal release and inhibition of β-tubulin deactylase. Nucleic Acids Res. 2017;45:e38 pubmed publisher
  • immunocytochemistry; mouse; 1:300; loading ...; fig 7a
  • immunocytochemistry; human; 1:300; loading ...; fig s2
Yu F, Sharma S, Skowronek A, Erdmann K. The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis. Sci Rep. 2016;6:35399 pubmed publisher
  • immunohistochemistry; human; 1:1000; fig 3S2B
Dye B, Dedhia P, Miller A, Nagy M, White E, Shea L, et al. A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids. elife. 2016;5: pubmed publisher
  • immunohistochemistry; fruit fly ; 1:100; loading ...; fig 2a
Vieillard J, Paschaki M, Duteyrat J, Augière C, Cortier E, Lapart J, et al. Transition zone assembly and its contribution to axoneme formation in Drosophila male germ cells. J Cell Biol. 2016;214:875-89 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:50; fig 5
Zak M, van Oort T, Hendriksen F, Garcia M, Vassart G, Grolman W. LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea. Front Cell Neurosci. 2016;10:186 pubmed publisher
  • immunocytochemistry; mouse; fig 1
Villa M, Crotta S, Dingwell K, Hirst E, Gialitakis M, Ahlfors H, et al. The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis. Nat Commun. 2016;7:12652 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1b
Chien J, Tsen S, Chien C, Liu H, Tung C, Lin C. ?TAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells. Cell Death Discov. 2016;2:16006 pubmed publisher
  • immunocytochemistry; human; 1:10,000; loading ...; fig 1b, 3a
Ghossoub R, Lindbæk L, Molla Herman A, Schmitt A, Christensen S, Benmerah A. Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy. Methods Mol Biol. 2016;1454:35-51 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 1A
Kim M, Froese C, Xie H, Trimble W. Immunofluorescent staining of septins in primary cilia. Methods Cell Biol. 2016;136:269-83 pubmed publisher
  • immunohistochemistry; human; 1:6000; fig 3
Grammatikopoulos T, Sambrotta M, Strautnieks S, Foskett P, Knisely A, Wagner B, et al. Mutations in DCDC2 (doublecortin domain containing protein 2) in neonatal sclerosing cholangitis. J Hepatol. 2016;65:1179-1187 pubmed publisher
  • immunohistochemistry; zebrafish ; loading ...; fig s2a
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3m
Pollock L, Gupta N, Chen X, Luna E, McDermott B. Supervillin Is a Component of the Hair Cell's Cuticular Plate and the Head Plates of Organ of Corti Supporting Cells. PLoS ONE. 2016;11:e0158349 pubmed publisher
  • immunocytochemistry; mouse; 1:2000; fig 10
  • western blot; mouse; 1:4000; fig 13
Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, et al. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochem Cell Biol. 2016;146:489-512 pubmed publisher
  • immunocytochemistry; human; fig 5
Wang Y, Li Y, Hu G, Huang X, Rao H, Xiong X, et al. Nek2A phosphorylates and stabilizes SuFu: A new strategy of Gli2/Hedgehog signaling regulatory mechanism. Cell Signal. 2016;28:1304-13 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:250; loading ...; fig 3g
Turner K, Hawkins T, Yáñez J, Anadón R, Wilson S, Folgueira M. Afferent Connectivity of the Zebrafish Habenulae. Front Neural Circuits. 2016;10:30 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:800; loading ...; fig 5d
Petit F, Deng C, Jamin S. Partial Müllerian Duct Retention in Smad4 Conditional Mutant Male Mice. Int J Biol Sci. 2016;12:667-76 pubmed publisher
  • immunocytochemistry; mouse; 1:300; fig 1
Pandolfini L, Luzi E, Bressan D, Ucciferri N, Bertacchi M, Brandi R, et al. RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells. Genome Biol. 2016;17:94 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 1
Guen V, Gamble C, Perez D, Bourassa S, Zappel H, Gartner J, et al. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis. Cell Cycle. 2016;15:678-88 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:500; fig 2
Suli A, Pujol R, Cunningham D, Hailey D, Prendergast A, Rubel E, et al. Innervation regulates synaptic ribbons in lateral line mechanosensory hair cells. J Cell Sci. 2016;129:2250-60 pubmed publisher
  • immunohistochemistry; freshwater planarian; 1:500; fig 4
Peiris T, Ramirez D, Barghouth P, Oviedo N. The Akt signaling pathway is required for tissue maintenance and regeneration in planarians. BMC Dev Biol. 2016;16:7 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 5
  • immunohistochemistry; mouse; 1:1000; fig 2
Hakim S, Dyson J, Feeney S, Davies E, Sriratana A, Koenig M, et al. Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling. Hum Mol Genet. 2016;25:2295-2313 pubmed
  • immunocytochemistry; mouse; 1:3000; fig 4
Balasooriya G, Johnson J, Basson M, Rawlins E. An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium. Dev Cell. 2016;37:85-97 pubmed publisher
  • immunocytochemistry; mouse; fig 7
Yadav P, Selvaraj B, Bender F, Behringer M, Moradi M, Sivadasan R, et al. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathol. 2016;132:93-110 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s1
Delling M, Indzhykulian A, Liu X, Li Y, Xie T, Corey D, et al. Primary cilia are not calcium-responsive mechanosensors. Nature. 2016;531:656-60 pubmed publisher
  • immunocytochemistry; mouse; fig s2
Pal K, Hwang S, Somatilaka B, Badgandi H, Jackson P, DeFea K, et al. Smoothened determines ?-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. J Cell Biol. 2016;212:861-75 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig s3
Kamiyama D, Sekine S, Barsi Rhyne B, Hu J, Chen B, Gilbert L, et al. Versatile protein tagging in cells with split fluorescent protein. Nat Commun. 2016;7:11046 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 6a'
Katoh Y, Terada M, Nishijima Y, Takei R, Nozaki S, Hamada H, et al. Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex. J Biol Chem. 2016;291:10962-75 pubmed publisher
  • immunocytochemistry; African green monkey; fig 1
  • western blot; human; fig 1
Kovalevich J, Cornec A, Yao Y, James M, Crowe A, Lee V, et al. Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies. J Pharmacol Exp Ther. 2016;357:432-50 pubmed publisher
  • immunocytochemistry; human; 1:2000; fig 4h
Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K. Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun. 2016;7:10777 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:250; loading ...
Laird A, Mackovski N, Rinkwitz S, Becker T, Giacomotto J. Tissue-specific models of spinal muscular atrophy confirm a critical role of SMN in motor neurons from embryonic to adult stages. Hum Mol Genet. 2016;25:1728-38 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 4
Vukićević T, Schulz M, Faust D, Klussmann E. The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells-a Potential Target for Pharmacological Intervention in Cardiovascular Diseases. Front Pharmacol. 2016;7:23 pubmed publisher
  • immunocytochemistry; mouse; fig 7
Bhattacharyya S, Rainey M, Arya P, Mohapatra B, Mushtaq I, Dutta S, et al. Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016;6:20727 pubmed publisher
  • immunocytochemistry; rat; 1:3000; fig 5
Raredon M, Ghaedi M, Calle E, Niklason L. A Rotating Bioreactor for Scalable Culture and Differentiation of Respiratory Epithelium. Cell Med. 2015;7:109-21 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig s3
Tadokoro T, Gao X, Hong C, Hotten D, Hogan B. BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors. Development. 2016;143:764-73 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 2
Grego Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson K. The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. elife. 2016;5:e12034 pubmed publisher
  • western blot; dogs; 1:4000; fig 4
Tien S, Lee H, Yang Y, Lin M, Chen Y, Chang Z. The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42. Nat Commun. 2016;7:10420 pubmed publisher
  • western blot; human; fig 1
Terranova Barberio M, Roca M, Zotti A, Leone A, Bruzzese F, Vitagliano C, et al. Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression. Oncotarget. 2016;7:7715-31 pubmed publisher
  • immunohistochemistry; Crepidula fornicata; 1:400; loading ...; fig s12bb
Lyons D, Perry K, Henry J. Spiralian gastrulation: germ layer formation, morphogenesis, and fate of the blastopore in the slipper snail Crepidula fornicata. Evodevo. 2015;6:24 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 7a
Farina F, Gaillard J, Guérin C, Couté Y, Sillibourne J, Blanchoin L, et al. The centrosome is an actin-organizing centre. Nat Cell Biol. 2016;18:65-75 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 5
Cazals Y, Bevengut M, Zanella S, Brocard F, Barhanin J, Gestreau C. KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing. Nat Commun. 2015;6:8780 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 2,3,4,5,8
Gao X, Bali A, Randell S, Hogan B. GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells. J Cell Biol. 2015;211:669-82 pubmed publisher
  • immunocytochemistry; human; fig 2
Chauhan S, Ahmed Z, Bradfute S, Arko Mensah J, Mandell M, Won Choi S, et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nat Commun. 2015;6:8620 pubmed publisher
  • western blot; domestic sheep; 1:1000; fig 1a
Teng R, Wu T, Afolayan A, Konduri G. Nitrotyrosine impairs mitochondrial function in fetal lamb pulmonary artery endothelial cells. Am J Physiol Cell Physiol. 2016;310:C80-8 pubmed publisher
  • immunocytochemistry; human; 1:10,000; fig 3
Bizet A, Becker Heck A, Ryan R, Weber K, Filhol E, Krug P, et al. Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Commun. 2015;6:8666 pubmed publisher
  • western blot; mouse; fig 2
Matthews G, Mehdipour P, Cluse L, Falkenberg K, Wang E, Roth M, et al. Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies. Blood. 2015;126:2392-403 pubmed publisher
  • immunohistochemistry; zebrafish ; fig 1
Meda F, Gauron C, Rampon C, Teillon J, Volovitch M, Vriz S. Nerves Control Redox Levels in Mature Tissues Through Schwann Cells and Hedgehog Signaling. Antioxid Redox Signal. 2016;24:299-311 pubmed publisher
  • immunocytochemistry; mouse; fig 4
Jiang S, Du J, Kong Q, Li C, Li Y, Sun H, et al. A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation. PLoS ONE. 2015;10:e0139830 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 2
Shnitsar I, Bashkurov M, Masson G, Ogunjimi A, Mosessian S, Cabeza E, et al. PTEN regulates cilia through Dishevelled. Nat Commun. 2015;6:8388 pubmed publisher
  • immunocytochemistry; human; 1:10,000; fig 6a
Raman M, Sergeev M, Garnaas M, Lydeard J, Huttlin E, Goessling W, et al. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nat Cell Biol. 2015;17:1356-69 pubmed publisher
  • immunocytochemistry; mouse
Stephen L, Tawamie H, Davis G, Tebbe L, Nurnberg P, Nurnberg G, et al. TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23). elife. 2015;4: pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 3
Jiang L, Tam B, Ying G, Wu S, Hauswirth W, Frederick J, et al. Kinesin family 17 (osmotic avoidance abnormal-3) is dispensable for photoreceptor morphology and function. FASEB J. 2015;29:4866-80 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Kim H, Nagano Y, Choi S, Park S, Kim H, Yao T, et al. HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation. Biochem Biophys Res Commun. 2015;464:1235-1240 pubmed publisher
  • immunocytochemistry; human; fig 6
  • western blot; human; 1:2000; fig 6
Sarma P, Bag I, Ramaiah M, Kamal A, Bhadra U, Pal Bhadra M. Bisindole-PBD regulates breast cancer cell proliferation via SIRT-p53 axis. Cancer Biol Ther. 2015;16:1486-501 pubmed publisher
  • immunocytochemistry; human
Alby C, Piquand K, Huber C, Megarbané A, Ichkou A, Legendre M, et al. Mutations in KIAA0586 Cause Lethal Ciliopathies Ranging from a Hydrolethalus Phenotype to Short-Rib Polydactyly Syndrome. Am J Hum Genet. 2015;97:311-8 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1f
  • western blot; human; loading ...; fig 2a
Cho Y, Park D, Cavalli V. Filamin A is required in injured axons for HDAC5 activity and axon regeneration. J Biol Chem. 2015;290:22759-70 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, et al. Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015;6:7531 pubmed publisher
  • immunohistochemistry; human; fig 6
Xu Q, Zhang Y, Wei Q, Huang Y, Li Y, Ling K, et al. BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors. Sci Rep. 2015;5:11855 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
  • immunocytochemistry; mouse; 1:8000
Maggiorani D, Dissard R, Belloy M, Saulnier Blache J, Casemayou A, Ducassé L, et al. Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells. PLoS ONE. 2015;10:e0131416 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 1
Watson J, Rulands S, Wilkinson A, Wuidart A, Ousset M, Van Keymeulen A, et al. Clonal Dynamics Reveal Two Distinct Populations of Basal Cells in Slow-Turnover Airway Epithelium. Cell Rep. 2015;12:90-101 pubmed publisher
  • immunocytochemistry; human; 1:250
Kowal T, Falk M. Primary cilia found on HeLa and other cancer cells. Cell Biol Int. 2015;39:1341-7 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 1
  • immunocytochemistry; mouse; 1:1000; fig s3
Abdelhamed Z, Natarajan S, Wheway G, Inglehearn C, Toomes C, Johnson C, et al. The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway. Dis Model Mech. 2015;8:527-41 pubmed publisher
  • western blot; mouse; fig 3
Jackson B, Ivanova I, Dagnino L. An ELMO2-RhoG-ILK network modulates microtubule dynamics. Mol Biol Cell. 2015;26:2712-25 pubmed publisher
  • immunohistochemistry; mouse; 1:1000
  • immunohistochemistry; chicken
Stasiulewicz M, Gray S, Mastromina I, Silva J, Björklund M, Seymour P, et al. A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo. Development. 2015;142:2291-303 pubmed publisher
  • immunocytochemistry; Octopus bimaculoides; loading ...; fig 4d
Ramirez M, Oakley T. Eye-independent, light-activated chromatophore expansion (LACE) and expression of phototransduction genes in the skin of Octopus bimaculoides. J Exp Biol. 2015;218:1513-20 pubmed publisher
  • immunocytochemistry; dogs
Reales E, Bernabé Rubio M, Casares Arias J, Rentero C, Fernández Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse
Song W, Cho Y, Watt D, Cavalli V. Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon Regeneration. J Biol Chem. 2015;290:14765-75 pubmed publisher
  • immunocytochemistry; mouse; 1:1000
Liu J, Zeng H, Liu A. The loss of Hh responsiveness by a non-ciliary Gli2 variant. Development. 2015;142:1651-60 pubmed publisher
  • immunocytochemistry; human; 10 ug/ml
Rappa G, Green T, Karbanová J, Corbeil D, Lorico A. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget. 2015;6:7970-91 pubmed
  • immunocytochemistry; mouse; 1:200
Zhang L, Li W, Ni J, Wu J, Liu J, Zhang Z, et al. RC/BTB2 is essential for formation of primary cilia in mammalian cells. Cytoskeleton (Hoboken). 2015;72:171-81 pubmed publisher
  • immunocytochemistry; mouse; 1:500
  • western blot; mouse; 1:1600
Fernandes S, Salta S, Summavielle T. Methamphetamine promotes α-tubulin deacetylation in endothelial cells: the protective role of acetyl-l-carnitine. Toxicol Lett. 2015;234:131-8 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000
  • immunocytochemistry; mouse; 1:1000
  • western blot; mouse; 1:500
  • immunohistochemistry - frozen section; pigs ; 1:1000
Narita K, Sasamoto S, Koizumi S, Okazaki S, Nakamura H, Inoue T, et al. TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport. FASEB J. 2015;29:2247-59 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:1000
Kita E, Scott E, Goodhill G. The influence of activity on axon pathfinding in the optic tectum. Dev Neurobiol. 2015;75:608-20 pubmed publisher
  • western blot; human; 1:3000; fig 6a
  • immunocytochemistry; mouse; 1:1000; fig 1b
Rao Y, Hao R, Wang B, Yao T. A Mec17-Myosin II Effector Axis Coordinates Microtubule Acetylation and Actin Dynamics to Control Primary Cilium Biogenesis. PLoS ONE. 2014;9:e114087 pubmed publisher
  • immunocytochemistry; mouse; 1:5000
Liu J, Bain L. Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol. 2014;281:243-53 pubmed publisher
  • immunocytochemistry; mouse; 1:4000; fig 1
Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, et al. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nat Commun. 2014;5:5482 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 1
Kim M, Kim M, Lee M, Kim C, Lim D. The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis. Nat Commun. 2014;5:5370 pubmed publisher
  • immunocytochemistry; mouse; 1:20000
Giles R, Ajzenberg H, Jackson P. 3D spheroid model of mIMCD3 cells for studying ciliopathies and renal epithelial disorders. Nat Protoc. 2014;9:2725-31 pubmed publisher
  • western blot; mouse; fig 3c
Sleiman S, Olson D, Bourassa M, Karuppagounder S, Zhang Y, Gale J, et al. Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition. J Neurosci. 2014;34:14328-37 pubmed publisher
  • immunocytochemistry; human; 1:3000
Vestergaard M, Awan A, Warzecha C, Christensen S, Andersen C. Immunofluorescence Microscopy and mRNA Analysis of Human Embryonic Stem Cells (hESCs) Including Primary Cilia Associated Signaling Pathways. Methods Mol Biol. 2016;1307:123-40 pubmed publisher
  • immunocytochemistry; mouse; fig 4
Gegg M, Böttcher A, Burtscher I, Hasenoeder S, Van Campenhout C, Aichler M, et al. Flattop regulates basal body docking and positioning in mono- and multiciliated cells. elife. 2014;3: pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 5
Goggolidou P, Stevens J, Agueci F, Keynton J, Wheway G, Grimes D, et al. ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Development. 2014;141:3966-77 pubmed publisher
  • western blot; mouse
McGinnis L, Pelech S, Kinsey W. Post-ovulatory aging of oocytes disrupts kinase signaling pathways and lysosome biogenesis. Mol Reprod Dev. 2014;81:928-45 pubmed publisher
  • immunocytochemistry; human; 1:2000; fig 1-s3
Wang W, Wu T, Kirschner M. The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium. elife. 2014;3:e03083 pubmed publisher
  • immunohistochemistry; Xenopus laevis; fig 2
Werner M, Mitchell J, Putzbach W, Bacon E, Kim S, Mitchell B. Radial intercalation is regulated by the Par complex and the microtubule-stabilizing protein CLAMP/Spef1. J Cell Biol. 2014;206:367-76 pubmed publisher
  • immunocytochemistry; Atlantic halibut; 1:1000
Eilertsen M, Drivenes O, Edvardsen R, Bradley C, Ebbesson L, Helvik J. Exorhodopsin and melanopsin systems in the pineal complex and brain at early developmental stages of Atlantic halibut (Hippoglossus hippoglossus). J Comp Neurol. 2014;522:4003-22 pubmed publisher
  • immunocytochemistry; zebrafish ; 1:500
Bernier R, Golzio C, Xiong B, Stessman H, Coe B, Penn O, et al. Disruptive CHD8 mutations define a subtype of autism early in development. Cell. 2014;158:263-276 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig s7
Tsurusaki Y, Koshimizu E, Ohashi H, Phadke S, Kou I, Shiina M, et al. De novo SOX11 mutations cause Coffin-Siris syndrome. Nat Commun. 2014;5:4011 pubmed publisher
  • immunocytochemistry; African green monkey; 1:10000
Kielar M, Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci. 2014;17:923-33 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Liu Y, Tsai I, Morleo M, Oh E, Leitch C, Massa F, et al. Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators. J Clin Invest. 2014;124:2059-70 pubmed
  • immunohistochemistry - frozen section; mouse
Crouse J, Lopes V, SanAgustin J, Keady B, Williams D, Pazour G. Distinct functions for IFT140 and IFT20 in opsin transport. Cytoskeleton (Hoboken). 2014;71:302-10 pubmed publisher
  • western blot; pigs
  • western blot; human
Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed publisher
  • immunocytochemistry; mouse; 1:100
Romani S, Illi B, De Mori R, Savino M, Gleeson J, Valente E. The ciliary proteins Meckelin and Jouberin are required for retinoic acid-dependent neural differentiation of mouse embryonic stem cells. Differentiation. 2014;87:134-146 pubmed publisher
  • immunocytochemistry; mouse
  • ELISA; mouse
Follit J, San Agustin J, Jonassen J, Huang T, Rivera Perez J, Tremblay K, et al. Arf4 is required for Mammalian development but dispensable for ciliary assembly. PLoS Genet. 2014;10:e1004170 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100
Maurya D, Menini A. Developmental expression of the calcium-activated chloride channels TMEM16A and TMEM16B in the mouse olfactory epithelium. Dev Neurobiol. 2014;74:657-75 pubmed publisher
  • immunocytochemistry; human; 1:500
Jodoin J, Shboul M, Albrecht T, Lee E, Wagner E, Reversade B, et al. The snRNA-processing complex, Integrator, is required for ciliogenesis and dynein recruitment to the nuclear envelope via distinct mechanisms. Biol Open. 2013;2:1390-6 pubmed publisher
  • immunocytochemistry; human; fig 6
Law B, Spain V, Leinster V, Chia R, Beilina A, Cho H, et al. A direct interaction between leucine-rich repeat kinase 2 and specific ?-tubulin isoforms regulates tubulin acetylation. J Biol Chem. 2014;289:895-908 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Whiteman E, Fan S, Harder J, Walton K, Liu C, Soofi A, et al. Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol. 2014;34:43-56 pubmed publisher
  • immunocytochemistry; human
  • immunocytochemistry; mouse
Drivas T, Holzbaur E, Bennett J. Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. J Clin Invest. 2013;123:4525-39 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 1
DelGiorno K, Hall J, Takeuchi K, Pan F, Halbrook C, Washington M, et al. Identification and manipulation of biliary metaplasia in pancreatic tumors. Gastroenterology. 2014;146:233-44.e5 pubmed publisher
  • western blot; rat
Yi X, Pashaj A, Xia M, Moreau R. Reversal of obesity-induced hypertriglyceridemia by (R)-?-lipoic acid in ZDF (fa/fa) rats. Biochem Biophys Res Commun. 2013;439:390-5 pubmed publisher
  • immunocytochemistry; human
Tucker B, Mullins R, Streb L, Anfinson K, Eyestone M, Kaalberg E, et al. Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. elife. 2013;2:e00824 pubmed publisher
  • immunocytochemistry; human; fig 3a
  • immunohistochemistry; mouse; fig 3c
Zhang Y, Seo S, Bhattarai S, Bugge K, Searby C, Zhang Q, et al. BBS mutations modify phenotypic expression of CEP290-related ciliopathies. Hum Mol Genet. 2014;23:40-51 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000; fig 4
Gonzalez Silva C, Vera J, Bono M, Gonzalez Billault C, Baxter B, Hansen A, et al. Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons. PLoS ONE. 2013;8:e69295 pubmed publisher
  • immunohistochemistry - paraffin section; zebrafish ; 1:500
Kim S, Scott S, Bennett M, Carson R, Fessel J, Brown H, et al. Multi-organ abnormalities and mTORC1 activation in zebrafish model of multiple acyl-CoA dehydrogenase deficiency. PLoS Genet. 2013;9:e1003563 pubmed publisher
  • immunocytochemistry; human; 1:2000
Luijten M, Basten S, Claessens T, Vernooij M, Scott C, Janssen R, et al. Birt-Hogg-Dube syndrome is a novel ciliopathy. Hum Mol Genet. 2013;22:4383-97 pubmed publisher
  • western blot; mouse
Ma T, Galimberti F, Erkmen C, Memoli V, Chinyengetere F, SEMPERE L, et al. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer. Mol Cancer Ther. 2013;12:1545-55 pubmed publisher
  • immunocytochemistry; mouse; 1:200
  • western blot; mouse; 1:10000
Lang J, Maeda Y, Bannerman P, Xu J, Horiuchi M, Pleasure D, et al. Adenomatous polyposis coli regulates oligodendroglial development. J Neurosci. 2013;33:3113-30 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000
Willaredt M, Gorgas K, Gardner H, Tucker K. Multiple essential roles for primary cilia in heart development. Cilia. 2012;1:23 pubmed publisher
  • immunohistochemistry; freshwater planarian; 1:1000
Beane W, Morokuma J, Lemire J, Levin M. Bioelectric signaling regulates head and organ size during planarian regeneration. Development. 2013;140:313-22 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:800
Bubenshchikova E, Ichimura K, Fukuyo Y, Powell R, Hsu C, Morrical S, et al. Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis. Biol Open. 2012;1:588-96 pubmed publisher
  • western blot; human
Coffey K, Blackburn T, Cook S, Golding B, Griffin R, Hardcastle I, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS ONE. 2012;7:e45539 pubmed publisher
  • immunohistochemistry - paraffin section; human
Cigna N, Farrokhi Moshai E, Brayer S, Marchal Sommé J, Wemeau Stervinou L, Fabre A, et al. The hedgehog system machinery controls transforming growth factor-?-dependent myofibroblastic differentiation in humans: involvement in idiopathic pulmonary fibrosis. Am J Pathol. 2012;181:2126-37 pubmed publisher
  • immunohistochemistry - frozen section; marine lamprey; 1:500
Barreiro Iglesias A, Villar Cerviño V, Villar Cheda B, Anadón R, Rodicio M. Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. J Comp Neurol. 2008;511:438-53 pubmed publisher
  • blocking or activating experiments; human
Werner S, Dotzlaf J, Smith R. MMP-28 as a regulator of myelination. BMC Neurosci. 2008;9:83 pubmed publisher
  • western blot; human
Pandithage R, Lilischkis R, Harting K, Wolf A, Jedamzik B, Lüscher Firzlaff J, et al. The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. J Cell Biol. 2008;180:915-29 pubmed publisher
Quadri R, Sertic S, Ghilardi A, Rondelli D, Gallo G, Del Giacco L, et al. Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation. Int J Mol Sci. 2021;22: pubmed publisher
Zilova L, Weinhardt V, Tavhelidse T, Schlagheck C, Thumberger T, Wittbrodt J. Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development. elife. 2021;10: pubmed publisher
Serifi I, Besta S, Karetsou Z, Giardoglou P, Beis D, Niewiadomski P, et al. Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling. Sci Rep. 2021;11:13940 pubmed publisher
Uehara T, Sanuki R, Ogura Y, Yokoyama A, Yoshida T, Futagawa H, et al. Recurrent NFIA K125E substitution represents a loss-of-function allele: Sensitive in vitro and in vivo assays for nontruncating alleles. Am J Med Genet A. 2021;185:2084-2093 pubmed publisher
Hać A, Pierzynowska K, Herman Antosiewicz A. S6K1 Is Indispensible for Stress-Induced Microtubule Acetylation and Autophagic Flux. Cells. 2021;10: pubmed publisher
Zhang K, Blauch L, Huang W, Marshall W, Tang S. Microfluidic guillotine reveals multiple timescales and mechanical modes of wound response in Stentor coeruleus. BMC Biol. 2021;19:63 pubmed publisher
Edwards Faret G, González Pinto K, Cebrian Silla A, Peñailillo J, Garcia Verdugo J, Larraín J. Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis. Neural Dev. 2021;16:2 pubmed publisher
Chen T, Huang B, Tang T, Chao Y, Xiao X, Lee P, et al. Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response. Cell Death Differ. 2021;: pubmed publisher
Barbeito P, Tachibana Y, Martin Morales R, Moreno P, Mykytyn K, Kobayashi T, et al. HTR6 and SSTR3 ciliary targeting relies on both IC3 loops and C-terminal tails. Life Sci Alliance. 2021;4: pubmed publisher
Wu L, Huang B, Lai S, Lin C, Lin H, Yang L, et al. SIRT1 activation by minocycline on regulation of microglial polarization homeostasis. Aging (Albany NY). 2020;12:17990-18007 pubmed publisher
Gerakopoulos V, Ngo P, Tsiokas L. Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway. Life Sci Alliance. 2020;3: pubmed publisher
Desai P, Stuck M, Lv B, Pazour G. Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling. J Cell Biol. 2020;219: pubmed publisher
Venugopal N, Ghosh A, Gala H, Aloysius A, Vyas N, Dhawan J. The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts. BMC Mol Cell Biol. 2020;21:25 pubmed publisher
Glaß H, Neumann P, Pal A, Reinhardt P, Storch A, Sterneckert J, et al. Combined Dendritic and Axonal Deterioration Are Responsible for Motoneuronopathy in Patient-Derived Neuronal Cell Models of Chorea-Acanthocytosis. Int J Mol Sci. 2020;21: pubmed publisher
Kim H, Jackson T, Stuckenholz C, Davidson L. Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates. Nat Commun. 2020;11:665 pubmed publisher
Chivukula R, Montoro D, Leung H, Yang J, Shamseldin H, Taylor M, et al. A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nat Med. 2020;26:244-251 pubmed publisher
Unlu G, Qi X, Gamazon E, Melville D, Patel N, Rushing A, et al. Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies. Nat Med. 2020;26:98-109 pubmed publisher
Vargas E, Matamoros A, Qiu J, Jan C, Wang Q, Gorczyca D, et al. The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration. Genes Dev. 2020;34:194-208 pubmed publisher
Thouvenin O, Keiser L, Cantaut Belarif Y, Carbó Tano M, Verweij F, Jurisch Yaksi N, et al. Origin and role of the cerebrospinal fluid bidirectional flow in the central canal. elife. 2020;9: pubmed publisher
Ki S, Kim J, Won S, Oh S, Lee I, Bae Y, et al. CEP41-mediated ciliary tubulin glutamylation drives angiogenesis through AURKA-dependent deciliation. EMBO Rep. 2020;21:e48290 pubmed publisher
Adalbert R, Kaieda A, Antoniou C, Loreto A, Yang X, Gilley J, et al. Novel HDAC6 Inhibitors Increase Tubulin Acetylation and Rescue Axonal Transport of Mitochondria in a Model of Charcot-Marie-Tooth Type 2F. ACS Chem Neurosci. 2020;11:258-267 pubmed publisher
Shafiquzzaman M, Biswas S, Li P, Mishina Y, Li B, Liu H. The noncanonical BMP signaling pathway plays an important role in club cell regeneration. Stem Cells. 2020;38:437-450 pubmed publisher
Sim H, Yun S, Kim H, Kwon K, Kim G, Yun S, et al. Simple Method To Characterize the Ciliary Proteome of Multiciliated Cells. J Proteome Res. 2020;19:391-400 pubmed publisher
Gliozzi M, Espiritu E, Shipman K, Rbaibi Y, Long K, Roy N, et al. Effects of Proximal Tubule Shortening on Protein Excretion in a Lowe Syndrome Model. J Am Soc Nephrol. 2020;31:67-83 pubmed publisher
Casagrande F, Amadeo A, Cartelli D, Calogero A, Modena D, Costa I, et al. The imbalance between dynamic and stable microtubules underlies neurodegeneration induced by 2,5-hexanedione. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165581 pubmed publisher
Konno T, Kohno T, Kikuchi S, Shimada H, Satohisa S, Takano K, et al. Localization of Tricellular Tight Junction Molecule LSR at Midbody and Centrosome During Cytokinesis in Human Epithelial Cells. J Histochem Cytochem. 2020;68:59-72 pubmed publisher
Suntres T, Daghfous G, Ananvoranich S, Dubuc R, Zielinski B. Sensory cutaneous papillae in the sea lamprey (Petromyzon marinus L.): II. Ontogeny and immunocytochemical characterization of solitary chemosensory cells. J Comp Neurol. 2020;528:865-878 pubmed publisher
Iruzubieta P, Monzon M, Castiella T, Ramirez T, Junquera C. Hedgehog signalling pathway activation in gastrointestinal stromal tumours is mediated by primary cilia. Gastric Cancer. 2020;23:64-72 pubmed publisher
York R, Byrne A, Abdilleh K, Patil C, Streelman T, Finger T, et al. Behavioral evolution contributes to hindbrain diversification among Lake Malawi cichlid fish. Sci Rep. 2019;9:19994 pubmed publisher
Bae J, Kang G, Min S, Jo D, Jung Y, Kim K, et al. Primary cilia mediate mitochondrial stress responses to promote dopamine neuron survival in a Parkinson's disease model. Cell Death Dis. 2019;10:952 pubmed publisher
Kim E, Jiang M, Huang H, Zhang Y, Tjota N, Gao X, et al. Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation. Dev Cell. 2019;51:675-683.e4 pubmed publisher
Wildner J, Friemel A, Jennewein L, Roth S, Ritter A, Schüttler C, et al. RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta. Cells. 2019;8: pubmed publisher
Hilgendorf K, Johnson C, Mezger A, Rice S, Norris A, Demeter J, et al. Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis. Cell. 2019;179:1289-1305.e21 pubmed publisher
Fumoto K, Takigawa Imamura H, Sumiyama K, Yoshimura S, Maehara N, Kikuchi A. Mark1 regulates distal airspace expansion through type I pneumocyte flattening in lung development. J Cell Sci. 2019;132: pubmed publisher
Valque H, Gouyer V, Duez C, Leboeuf C, Marquillies P, Le Bert M, et al. Muc5b-deficient mice develop early histological lung abnormalities. Biol Open. 2019;8: pubmed publisher
Sahabandu N, Kong D, Magidson V, Nanjundappa R, Sullenberger C, Mahjoub M, et al. Expansion microscopy for the analysis of centrioles and cilia. J Microsc. 2019;: pubmed publisher
Sechi S, Frappaolo A, Karimpour Ghahnavieh A, Gottardo M, Burla R, Di Francesco L, et al. Drosophila Doublefault protein coordinates multiple events during male meiosis by controlling mRNA translation. Development. 2019;146: pubmed publisher
Wang C, Su M, Cheng H, Kuo P, Tsai P. Fetuin-A Inhibits Placental Cell Growth and Ciliogenesis in Gestational Diabetes Mellitus. Int J Mol Sci. 2019;20: pubmed publisher
Rawlinson K, Lapraz F, Ballister E, Terasaki M, Rodgers J, McDowell R, et al. Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment. elife. 2019;8: pubmed publisher
Beyer M, Romanski A, Mustafa A, Pons M, Büchler I, Vogel A, et al. HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1. Cancers (Basel). 2019;11: pubmed publisher
Blasius T, Takao D, Verhey K. NPHP proteins are binding partners of nucleoporins at the base of the primary cilium. PLoS ONE. 2019;14:e0222924 pubmed publisher
Hurley B, Jugo R, Snow R, Samuels T, Yonker L, Mou H, et al. Pepsin Triggers Neutrophil Migration Across Acid Damaged Lung Epithelium. Sci Rep. 2019;9:13778 pubmed publisher
Zhou H, Zheng T, Wang T, Li Q, Wang F, Liang X, et al. CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment. BMC Biol. 2019;17:73 pubmed publisher
Fillatre J, Fauny J, Fels J, Li C, Goll M, Thisse C, et al. TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in zebrafish. elife. 2019;8: pubmed publisher
Castro Sánchez S, Suarez Bregua P, Novas R, Álvarez Satta M, Badano J, Rotllant J, et al. Functional analysis of new human Bardet-Biedl syndrome loci specific variants in the zebrafish model. Sci Rep. 2019;9:12936 pubmed publisher
He Y, Li X, Gao M, Liu H, Gu L. Loss of HDAC3 contributes to meiotic defects in aged oocytes. Aging Cell. 2019;18:e13036 pubmed publisher
Vargas Hurtado D, Brault J, Piolot T, Leconte L, Da Silva N, Pennetier C, et al. Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development. Curr Biol. 2019;29:2993-3005.e9 pubmed publisher
Walker R, Keynton J, Grimes D, Sreekumar V, Williams D, Esapa C, et al. Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model. Nat Commun. 2019;10:4072 pubmed publisher
Kim M, Mun H, Sung C, Cho E, Jeon H, Chun S, et al. Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening. Nat Commun. 2019;10:3991 pubmed publisher
Fréal A, Rai D, Tas R, Pan X, Katrukha E, van de Willige D, et al. Feedback-Driven Assembly of the Axon Initial Segment. Neuron. 2019;104:305-321.e8 pubmed publisher
Beckers P, Helm C, Bartolomaeus T. The anatomy and development of the nervous system in Magelonidae (Annelida) - insights into the evolution of the annelid brain. BMC Evol Biol. 2019;19:173 pubmed publisher
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product information
Product No. :
T7451
Product Name :
Monoclonal Anti-Acetylated Tubulin antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
6-11B-1
Applications/Description :
Suitable for dot blot; western blot: 0.03-0.06 μg/mL using total rat brain extract; radioimmunoassay; immunohistochemistry; electron microscopy
Species Reactivity :
monkey, protista, mouse, pig, human, bovine, invertebrates, rat, hamster, plant, frog, chicken
Isotype :
IgG2b
Concentration :
~1 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA