product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-γ-Tubulin antibody produced in mouse
catalog :
T6557
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GTU-88
reactivity :
Japanese rice fish, African green monkey, human, mouse, rat, dogs, chicken, bovine, pigs , zebrafish , fruit fly , Xenopus laevis
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 1102
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 6b
Riley L, Zhang X, Douglas C, Mijares J, Hammers D, Wolff C, et al. The skeletal muscle circadian clock regulates titin splicing through RBM20. elife. 2022;11: pubmed publisher
  • immunohistochemistry - frozen section; human; 1:2000; fig s1g
Schembs L, Willems A, Hasenpusch Theil K, Cooper J, Whiting K, Burr K, et al. The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling. Cell Rep. 2022;39:110811 pubmed publisher
  • immunocytochemistry; mouse; 1:5000; loading ...; fig 3f
Turn R, Linnert J, Gigante E, Wolfrum U, Caspary T, Kahn R. Roles for ELMOD2 and Rootletin in ciliogenesis. Mol Biol Cell. 2021;32:800-822 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1e''
Qiu H, Fujisawa S, Nozaki S, Katoh Y, Nakayama K. Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry. Biol Open. 2021;10: pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 6a
Chong W, Wang W, Lo C, Chiu T, Chang T, Liu Y, et al. Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 6d
Reynders M, Matsuura B, Bérouti M, Simoneschi D, Marzio A, Pagano M, et al. PHOTACs enable optical control of protein degradation. Sci Adv. 2020;6:eaay5064 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 5d
  • western blot; mouse; 1:1000; loading ...; fig 6b
Bowie E, Goetz S. TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; loading ...; fig s5b
Lee C, Aizawa K, Jiang J, Kung S, Jain R. JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli. Sci Adv. 2019;5:eaav0318 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 7e
  • immunocytochemistry; human; 1:500; loading ...; fig 1a
Kim D, Ahn J, Han H, Kim H, Hwang J, Lee K, et al. Cep131 overexpression promotes centrosome amplification and colon cancer progression by regulating Plk4 stability. Cell Death Dis. 2019;10:570 pubmed publisher
  • western blot; human; 1:2000; fig 2c
Carvalho J, Fortunato I, Fonseca C, Pezzarossa A, Barbacena P, Domínguez Cejudo M, et al. Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration. elife. 2019;8: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2a, s2e
Douanne T, André Grégoire G, Thys A, Trillet K, Gavard J, Bidere N. CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1. Cell Rep. 2019;27:1657-1665.e4 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig s1d
  • western blot; human; 1:5000; loading ...; fig 5j
Tai Y, Gallo N, Wang M, Yu J, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. 2019;102:358-372.e9 pubmed publisher
  • western blot; human; 1:8000; loading ...; fig 5a
Paschos K, Bazot Q, Lees J, Farrell P, Allday M. Requirement for PRC1 subunit BMI1 in host gene activation by Epstein-Barr virus protein EBNA3C. Nucleic Acids Res. 2019;47:2807-2821 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:5000; fig 4e
Song P, Perkins B. Developmental expression of the zebrafish Arf-like small GTPase paralogs arl13a and arl13b. Gene Expr Patterns. 2018;29:82-87 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig s9a
Rai A, Chen J, Selbach M, Pelkmans L. Kinase-controlled phase transition of membraneless organelles in mitosis. Nature. 2018;559:211-216 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 2d
Connell M, Chen H, Jiang J, Kuan C, Fotovati A, Chu T, et al. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. elife. 2017;6: pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 3f
Chu T, Connell M, Zhou L, He Z, Won J, Chen H, et al. Cell Cycle-Dependent Tumor Engraftment and Migration Are Enabled by Aurora-A. Mol Cancer Res. 2018;16:16-31 pubmed publisher
  • western blot; human; loading ...; fig 1d
Lee I, Kim G, Bae J, Kim J, Rhee K, Hwang D. The DNA replication protein Cdc6 inhibits the microtubule-organizing activity of the centrosome. J Biol Chem. 2017;292:16267-16276 pubmed publisher
  • western blot; human; loading ...; fig 2a
Wei J, Xu H, Meng W. Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk. FEBS Lett. 2017;591:2379-2393 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2a
Joachim J, Razi M, Judith D, Wirth M, Calamita E, Encheva V, et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr Biol. 2017;27:2123-2136.e7 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3a
Wang Q, Tang Y, Xu Y, Xu S, Jiang Y, Dong Q, et al. The X-linked deubiquitinase USP9X is an integral component of centrosome. J Biol Chem. 2017;292:12874-12884 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 2g
Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, et al. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Sci Rep. 2017;7:1474 pubmed publisher
  • immunocytochemistry; Japanese rice fish; loading ...; fig 5c
Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, et al. Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses. Nat Commun. 2017;8:14090 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 3a
Funabashi T, Katoh Y, Michisaka S, Terada M, Sugawa M, Nakayama K. Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. Mol Biol Cell. 2017;28:624-633 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 8d
Sierra Potchanant E, Cerabona D, Sater Z, He Y, Sun Z, Gehlhausen J, et al. INPP5E Preserves Genomic Stability through Regulation of Mitosis. Mol Cell Biol. 2017;37: pubmed publisher
  • immunocytochemistry; human; 1:5000; loading ...; fig 1a
Yu Z, Mouillesseaux K, Kushner E, Bautch V. Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication. PLoS ONE. 2016;11:e0168334 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 4a'
Hirano T, Katoh Y, Nakayama K. Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors. Mol Biol Cell. 2017;28:429-439 pubmed publisher
  • immunocytochemistry; fruit fly ; 1:500; loading ...; fig 2c
Tirmarche S, Kimura S, Dubruille R, Horard B, Loppin B. Unlocking sperm chromatin at fertilization requires a dedicated egg thioredoxin in Drosophila. Nat Commun. 2016;7:13539 pubmed publisher
  • immunocytochemistry; mouse; 1:300; loading ...; fig s2a
Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  • immunocytochemistry; human; 1:1000; fig 4
Bertolin G, Sizaire F, Herbomel G, Reboutier D, Prigent C, Tramier M. A FRET biosensor reveals spatiotemporal activation and functions of aurora kinase A in living cells. Nat Commun. 2016;7:12674 pubmed publisher
  • immunocytochemistry; fruit fly ; 1:200; fig 2
Meghini F, Martins T, Tait X, Fujimitsu K, Yamano H, Glover D, et al. Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. Nat Commun. 2016;7:12607 pubmed publisher
  • immunocytochemistry; mouse; fig 1
Villa M, Crotta S, Dingwell K, Hirst E, Gialitakis M, Ahlfors H, et al. The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis. Nat Commun. 2016;7:12652 pubmed publisher
  • western blot; rat; 1:1000; fig 1
  • western blot; mouse; 1:1000; fig 1
Vingill S, Brockelt D, Lancelin C, Tatenhorst L, Dontcheva G, Preisinger C, et al. Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice. EMBO J. 2016;35:2008-25 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 1B
Kim M, Froese C, Xie H, Trimble W. Immunofluorescent staining of septins in primary cilia. Methods Cell Biol. 2016;136:269-83 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 4
Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016;214:155-66 pubmed publisher
  • western blot; human; 1:10,000; fig 1
Müller S, Balaz M, Stefanicka P, Varga L, Amri E, Ukropec J, et al. Proteomic Analysis of Human Brown Adipose Tissue Reveals Utilization of Coupled and Uncoupled Energy Expenditure Pathways. Sci Rep. 2016;6:30030 pubmed publisher
  • immunocytochemistry; mouse; fig 3
  • western blot; mouse; fig 7
  • western blot; human; fig s3
Muroyama A, Seldin L, Lechler T. Divergent regulation of functionally distinct γ-tubulin complexes during differentiation. J Cell Biol. 2016;213:679-92 pubmed publisher
  • immunohistochemistry; human; fig 4
Airik R, Schueler M, Airik M, Cho J, Ulanowicz K, Porath J, et al. SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling. PLoS ONE. 2016;11:e0156081 pubmed publisher
  • immunocytochemistry; mouse; fig 2
  • immunocytochemistry; human; fig 1
Cooley L, El Shikh M, Li W, Keim R, Zhang Z, Strauss J, et al. Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient mice. Sci Rep. 2016;6:25840 pubmed publisher
  • western blot; mouse; 1:10,000; fig 1
Lamar K, Bogdanovich S, Gardner B, Gao Q, Miller T, Earley J, et al. Overexpression of Latent TGF? Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGF?. PLoS Genet. 2016;12:e1006019 pubmed publisher
  • immunocytochemistry; human; 1:5000; fig 3
Kushner E, Ferro L, Yu Z, Bautch V. Excess centrosomes perturb dynamic endothelial cell repolarization during blood vessel formation. Mol Biol Cell. 2016;27:1911-20 pubmed publisher
  • western blot; mouse; 1:2000; fig 5
Bianchi E, Boekelheide K, Sigman M, Lamb D, Hall S, Hwang K. Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling Pathway. PLoS ONE. 2016;11:e0153968 pubmed publisher
  • western blot; human; 1:10,000; fig s5
Conway A, Van Nostrand E, Pratt G, Aigner S, Wilbert M, Sundararaman B, et al. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep. 2016;15:666-679 pubmed publisher
  • western blot; rat; fig 1
Fortes M, Marzuca Nassr G, Vitzel K, da Justa Pinheiro C, Newsholme P, Curi R. Housekeeping proteins: How useful are they in skeletal muscle diabetes studies and muscle hypertrophy models?. Anal Biochem. 2016;504:38-40 pubmed publisher
  • immunocytochemistry; mouse; fig 7
Yadav P, Selvaraj B, Bender F, Behringer M, Moradi M, Sivadasan R, et al. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathol. 2016;132:93-110 pubmed publisher
  • western blot; mouse; fig 7
Braun J, Meixner A, Brachner A, Foisner R. The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis. PLoS ONE. 2016;11:e0152278 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 4
  • western blot; human; 1:1000; fig 1
Chavali P, Chandrasekaran G, Barr A, Tátrai P, Taylor C, Papachristou E, et al. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun. 2016;7:11005 pubmed publisher
  • western blot; mouse; 1:500; fig 1
Obino D, Farina F, Malbec O, Sáez P, Maurin M, Gaillard J, et al. Actin nucleation at the centrosome controls lymphocyte polarity. Nat Commun. 2016;7:10969 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 6g
Katoh Y, Terada M, Nishijima Y, Takei R, Nozaki S, Hamada H, et al. Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex. J Biol Chem. 2016;291:10962-75 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Przedborski S, Mochizuki H, et al. Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nat Commun. 2016;7:10943 pubmed publisher
  • immunohistochemistry; mouse; 1:200; tbl 1
May Simera H. Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea. J Vis Exp. 2016;:53559 pubmed publisher
  • western blot; mouse; 1:5000; fig 1
Rai R, Chen Y, Lei M, Chang S. TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions. Nat Commun. 2016;7:10881 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; fig 1c
Di Pietro C, Marazziti D, La Sala G, Abbaszadeh Z, Golini E, Matteoni R, et al. Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma. Cell Mol Neurobiol. 2017;37:145-154 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 4d
Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K. Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun. 2016;7:10777 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4
Bhattacharyya S, Rainey M, Arya P, Mohapatra B, Mushtaq I, Dutta S, et al. Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016;6:20727 pubmed publisher
  • western blot; rat; 1:1000; fig 4
Nosak C, Silva P, Sollazzo P, Moon K, Odisho T, Foster L, et al. Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis. PLoS ONE. 2016;11:e0149177 pubmed publisher
  • immunohistochemistry; mouse; 1:400; fig 5
Taverna E, Mora Bermúdez F, Strzyz P, Florio M, Icha J, Haffner C, et al. Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells. Sci Rep. 2016;6:21206 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 2b
Lopes C, Aubert S, Bourgois Rocha F, Barnat M, Rego A, Déglon N, et al. Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells. PLoS ONE. 2016;11:e0148680 pubmed publisher
  • immunocytochemistry; rat; 1:400; loading ...; fig 7b
Gupta A, Schell M, Bhattacharjee A, Lutsenko S, Hubbard A. Myosin Vb mediates Cu+ export in polarized hepatocytes. J Cell Sci. 2016;129:1179-89 pubmed publisher
  • western blot; human; fig 1
Hasvold G, Lund Andersen C, Lando M, Patzke S, Hauge S, Suo Z, et al. Hypoxia-induced alterations of G2 checkpoint regulators. Mol Oncol. 2016;10:764-73 pubmed publisher
  • western blot; mouse; fig 5d
Kibe T, Zimmermann M, de Lange T. TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres. Mol Cell. 2016;61:236-46 pubmed publisher
  • immunocytochemistry; human; 1:2000
  • immunohistochemistry; human; 1:2000; fig s4
Hoang Minh L, Deleyrolle L, Siebzehnrubl D, Ugartemendia G, Futch H, Griffith B, et al. Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis. Oncotarget. 2016;7:7029-43 pubmed publisher
  • western blot; human; fig 1b
Hérate C, Ramdani G, Grant N, Marion S, Gasman S, Niedergang F, et al. Phospholipid Scramblase 1 Modulates FcR-Mediated Phagocytosis in Differentiated Macrophages. PLoS ONE. 2016;11:e0145617 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 4
Zhou H, Wang T, Zheng T, Teng J, Chen J. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun. 2016;7:10151 pubmed publisher
  • immunocytochemistry; human; fig 4
Toya M, Kobayashi S, Kawasaki M, Shioi G, Kaneko M, Ishiuchi T, et al. CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells. Proc Natl Acad Sci U S A. 2016;113:332-7 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 7d
Farina F, Gaillard J, Guérin C, Couté Y, Sillibourne J, Blanchoin L, et al. The centrosome is an actin-organizing centre. Nat Cell Biol. 2016;18:65-75 pubmed publisher
  • immunohistochemistry; Xenopus laevis; 1:100; loading ...; fig 2a
Gulsen T, Hadjicosti I, Li Y, Zhang X, Whitley P, Chalmers A. Truncated RASSF7 promotes centrosomal defects and cell death. Dev Biol. 2016;409:502-17 pubmed publisher
  • western blot; mouse; 1:5000; fig 4
Suárez Zamorano N, Fabbiano S, Chevalier C, Stojanović O, Colin D, Stevanović A, et al. Microbiota depletion promotes browning of white adipose tissue and reduces obesity. Nat Med. 2015;21:1497-1501 pubmed publisher
  • western blot; zebrafish ; fig s1
He Q, Liu K, Tian Z, Du S. The Effects of Hsp90α1 Mutations on Myosin Thick Filament Organization. PLoS ONE. 2015;10:e0142573 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 5
Gazea M, Tasouri E, Tolve M, Bosch V, Kabanova A, Gojak C, et al. Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Dev Biol. 2016;409:55-71 pubmed publisher
  • immunocytochemistry; human; fig 1
Fuchs M, Luthold C, Guilbert S, Varlet A, Lambert H, Jetté A, et al. A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis. PLoS Genet. 2015;11:e1005582 pubmed publisher
  • immunohistochemistry - paraffin section; fruit fly ; 1:100; loading ...
Tarayrah L, Li Y, Gan Q, Chen X. Epigenetic regulator Lid maintains germline stem cells through regulating JAK-STAT signaling pathway activity. Biol Open. 2015;4:1518-27 pubmed publisher
  • western blot; human; 1:1000; fig 1
Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
  • western blot; mouse; fig 1d
Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, et al. CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene. 2016;35:2893-901 pubmed publisher
  • immunocytochemistry; human; fig 3
Schnerch D, Nigg E. Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres. Oncogene. 2016;35:2711-22 pubmed publisher
  • immunocytochemistry; human; 1:5000; fig s2
Van de Mark D, Kong D, Loncarek J, Stearns T. MDM1 is a microtubule-binding protein that negatively regulates centriole duplication. Mol Biol Cell. 2015;26:3788-802 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 2
Kim S, Lee K, Choi J, Ringstad N, Dynlacht B. Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle. Nat Commun. 2015;6:8087 pubmed publisher
  • western blot; mouse; 1:1000
Sun D, Buttitta L. Protein phosphatase 2A promotes the transition to G0 during terminal differentiation in Drosophila. Development. 2015;142:3033-45 pubmed publisher
  • immunocytochemistry; human; 1:2000; fig 4
He S, Zhao Z, Yang Y, O Connell D, Zhang X, Oh S, et al. Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers. Nat Commun. 2015;6:7839 pubmed publisher
  • immunocytochemistry; human; 1:2000; fig 2
Chen C, Tian F, Lu L, Wang Y, Xiao Z, Yu C, et al. Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction. J Cell Sci. 2015;128:3290-303 pubmed publisher
  • immunocytochemistry; human; 1:800; loading ...; fig 2a
Restall I, Parolin D, Daneshmand M, Hanson J, Simard M, Fitzpatrick M, et al. PKCι depletion initiates mitotic slippage-induced senescence in glioblastoma. Cell Cycle. 2015;14:2938-48 pubmed publisher
  • western blot; mouse; fig 2f
Tattikota S, Rathjen T, Hausser J, Khedkar A, Kabra U, Pandey V, et al. miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism. J Biol Chem. 2015;290:20284-94 pubmed publisher
  • immunohistochemistry; mouse; 1:3000; fig s1
Clift D, Schuh M. A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes. Nat Commun. 2015;6:7217 pubmed publisher
  • immunocytochemistry; chicken; fig 5
Burgess S, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, et al. Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly. PLoS Genet. 2015;11:e1005345 pubmed publisher
  • immunocytochemistry; human
Hayashi M, Cesare A, Rivera T, Karlseder J. Cell death during crisis is mediated by mitotic telomere deprotection. Nature. 2015;522:492-6 pubmed publisher
  • western blot; human
Romano S, Xiao Y, Nakaya M, D Angelillo A, Chang M, Jin J, et al. FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma. Nucleic Acids Res. 2015;43:6983-93 pubmed publisher
  • western blot; human; 1:2000
Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed publisher
  • western blot; mouse; fig 1
Dennis M, Mantegazza A, Snir O, Tenza D, Acosta Ruiz A, Delevoye C, et al. BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery. J Cell Biol. 2015;209:563-77 pubmed publisher
  • western blot; human; fig 3
Palla A, Piazzolla D, Alcazar N, Cañamero M, Graña O, Gómez López G, et al. The pluripotency factor NANOG promotes the formation of squamous cell carcinomas. Sci Rep. 2015;5:10205 pubmed publisher
  • immunocytochemistry; dogs
Reales E, Bernabé Rubio M, Casares Arias J, Rentero C, Fernández Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 1
Prosser S, Sahota N, Pelletier L, Morrison C, Fry A. Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis. J Cell Biol. 2015;209:339-48 pubmed publisher
  • immunocytochemistry; human; 1:2000
Ohira M, Iwasaki Y, Tanaka C, Kuroki M, Matsuo N, Kitamura T, et al. A novel anti-microtubule agent with carbazole and benzohydrazide structures suppresses tumor cell growth in vivo. Biochim Biophys Acta. 2015;1850:1676-84 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 3
Qi S, Wang Z, Huang L, Liang L, Xian Y, Ouyang Y, et al. Casein kinase 1 (α, δ and ε) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression. Cell Cycle. 2015;14:1675-85 pubmed publisher
  • western blot; human; fig 2
Shen W, Liang X, Sun H, Crooke S. 2'-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF. Nucleic Acids Res. 2015;43:4569-78 pubmed publisher
  • immunocytochemistry; mouse
Vladar E, Lee Y, Stearns T, Axelrod J. Observing planar cell polarity in multiciliated mouse airway epithelial cells. Methods Cell Biol. 2015;127:37-54 pubmed publisher
  • western blot; human; fig 5
Batenburg N, Thompson E, Hendrickson E, Zhu X. Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation. EMBO J. 2015;34:1399-416 pubmed publisher
  • western blot; mouse; 1:500; fig 3
Boersma V, Moatti N, Segura Bayona S, Peuscher M, van der Torre J, Wevers B, et al. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection. Nature. 2015;521:537-540 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 3
Balboula A, Stein P, Schultz R, Schindler K. RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse. Biol Reprod. 2015;92:105 pubmed publisher
  • immunocytochemistry; human
Stellas D, Souliotis V, Bekyrou M, Smirlis D, Kirsch Volders M, Degrassi F, et al. Benzo[a]pyrene-induced cell cycle arrest in HepG2 cells is associated with delayed induction of mitotic instability. Mutat Res. 2014;769:59-68 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse
Liu C, Tan F, Xiao Z, Dawe G. Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression. J Biol Chem. 2015;290:12048-57 pubmed publisher
  • immunocytochemistry; mouse; 1:200
Zhang L, Li W, Ni J, Wu J, Liu J, Zhang Z, et al. RC/BTB2 is essential for formation of primary cilia in mammalian cells. Cytoskeleton (Hoboken). 2015;72:171-81 pubmed publisher
  • western blot; mouse; 1:10,000; fig 6
Jeanne M, Jorgensen J, Gould D. Molecular and Genetic Analyses of Collagen Type IV Mutant Mouse Models of Spontaneous Intracerebral Hemorrhage Identify Mechanisms for Stroke Prevention. Circulation. 2015;131:1555-65 pubmed publisher
  • immunocytochemistry; human; 1:1000
Prosser S, Morrison C. Centrin2 regulates CP110 removal in primary cilium formation. J Cell Biol. 2015;208:693-701 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 4
Grego Bessa J, Hildebrand J, Anderson K. Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015;142:1305-14 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 7
Arbeille E, Reynaud F, Sanyas I, Bozon M, Kindbeiter K, Causeret F, et al. Cerebrospinal fluid-derived Semaphorin3B orients neuroepithelial cell divisions in the apicobasal axis. Nat Commun. 2015;6:6366 pubmed publisher
  • immunocytochemistry; human
Gee H, Kim J, Lee M. Analysis of conventional and unconventional trafficking of CFTR and other membrane proteins. Methods Mol Biol. 2015;1270:137-54 pubmed publisher
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 1
Kratz A, Bärenz F, Richter K, Hoffmann I. Plk4-dependent phosphorylation of STIL is required for centriole duplication. Biol Open. 2015;4:370-7 pubmed publisher
  • western blot; rat; fig 4
Valianou M, Cox A, Pichette B, Hartley S, Paladhi U, Astrinidis A. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle. 2015;14:399-407 pubmed publisher
  • immunocytochemistry; human
Shibata H, Kanadome T, Sugiura H, Yokoyama T, Yamamuro M, Moss S, et al. A new role for annexin A11 in the early secretory pathway via stabilizing Sec31A protein at the endoplasmic reticulum exit sites (ERES). J Biol Chem. 2015;290:4981-93 pubmed publisher
  • immunocytochemistry; mouse
Hoon J, Li H, Koh C. POPX2 phosphatase regulates cell polarity and centrosome placement. Cell Cycle. 2014;13:2459-68 pubmed publisher
  • western blot; mouse; fig 2
Pekkonen P, Järviluoma A, Zinovkina N, Cvrljevic A, Prakash S, Westermarck J, et al. KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo. Cell Cycle. 2014;13:3670-84 pubmed publisher
  • immunocytochemistry; human; fig 9
Colbert P, Vermeer D, Wieking B, Lee J, Vermeer P. EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivity. Oncotarget. 2015;6:953-68 pubmed
  • immunocytochemistry; mouse; 1:1000; loading ...; fig s2
Umberger N, Caspary T. Ciliary transport regulates PDGF-AA/αα signaling via elevated mammalian target of rapamycin signaling and diminished PP2A activity. Mol Biol Cell. 2015;26:350-8 pubmed publisher
  • immunocytochemistry; pigs ; fig 2
Cai Y, Fedeles S, Dong K, Anyatonwu G, Onoe T, Mitobe M, et al. Altered trafficking and stability of polycystins underlie polycystic kidney disease. J Clin Invest. 2014;124:5129-44 pubmed publisher
  • immunocytochemistry; human; fig 3
Liang Y, Gao H, Lin S, Goss J, Du C, Li K. Mcph1/Brit1 deficiency promotes genomic instability and tumor formation in a mouse model. Oncogene. 2015;34:4368-78 pubmed publisher
  • western blot; mouse; 1:5000
Miyamoto Y, Mauer A, Kumar S, Mott J, Malhi H. Mmu-miR-615-3p regulates lipoapoptosis by inhibiting C/EBP homologous protein. PLoS ONE. 2014;9:e109637 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 1
Kong D, Farmer V, Shukla A, James J, Gruskin R, Kiriyama S, et al. Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles. J Cell Biol. 2014;206:855-65 pubmed publisher
  • immunocytochemistry; human; fig 2, 3, 4
Menhofer M, Bartel D, Liebl J, Kubisch R, Busse J, Wagner E, et al. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor. Cardiovasc Res. 2014;104:303-14 pubmed publisher
  • western blot; human; 1:3000; fig 8
Liu C, Lin C, Gao C, May Simera H, Swaroop A, Li T. Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a. Biol Open. 2014;3:861-70 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 5
Rosario C, Kazazian K, Zih F, Brashavitskaya O, Haffani Y, Xu R, et al. A novel role for Plk4 in regulating cell spreading and motility. Oncogene. 2015;34:3441-51 pubmed publisher
  • immunocytochemistry; mouse
Brown J, Santra T, Owens P, Morrison A, Barry F. Primary cilium-associated genes mediate bone marrow stromal cell response to hypoxia. Stem Cell Res. 2014;13:284-99 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 2
Lee Y, Santé J, Comerci C, Cyge B, Menezes L, Li F, et al. Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function. Mol Biol Cell. 2014;25:2919-33 pubmed publisher
  • western blot; human
Izumi H, Kaneko Y. Trim32 facilitates degradation of MYCN on spindle poles and induces asymmetric cell division in human neuroblastoma cells. Cancer Res. 2014;74:5620-30 pubmed publisher
  • western blot; mouse; 1:5000; fig 2
Booth A, Tarafder A, Hume A, Recchi C, Seabra M. A role for Na+,K+-ATPase ?1 in regulating Rab27a localisation on melanosomes. PLoS ONE. 2014;9:e102851 pubmed publisher
  • immunocytochemistry; human; 1:2000
Kotak S, Busso C, GONCZY P. NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane. EMBO J. 2014;33:1815-30 pubmed publisher
  • western blot; mouse; 1:10,000; fig 7
Piazzolla D, Palla A, Pantoja C, Canamero M, de Castro I, Ortega S, et al. Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia. Nat Commun. 2014;5:4226 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 6
Veleri S, Manjunath S, Fariss R, May Simera H, Brooks M, Foskett T, et al. Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis. Nat Commun. 2014;5:4207 pubmed publisher
  • immunocytochemistry; African green monkey; 1:800
Kielar M, Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci. 2014;17:923-33 pubmed publisher
  • western blot; human
Johansson P, Jeffery J, Al Ejeh F, Schulz R, Callen D, Kumar R, et al. SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G2 phase of cell cycle to prevent re-replication. J Biol Chem. 2014;289:18514-25 pubmed publisher
  • immunocytochemistry; human; 1:200
  • western blot; human
Kuo P, Huang Y, Hsieh C, Lee J, Lin B, Hung L. STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells. PLoS ONE. 2014;9:e93303 pubmed publisher
  • immunocytochemistry; human; 1:1000
Lee J, Hong W, Majeti R, Stearns T. Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms. PLoS ONE. 2014;9:e92641 pubmed publisher
  • immunocytochemistry; human
Deneubourg L, Elong Edimo W, Moreau C, Vanderwinden J, Erneux C. Phosphorylated SHIP2 on Y1135 localizes at focal adhesions and at the mitotic spindle in cancer cell lines. Cell Signal. 2014;26:1193-203 pubmed publisher
  • western blot; human; fig 4a
Davidson L, Muniz L, West S. 3' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells. Genes Dev. 2014;28:342-56 pubmed publisher
  • western blot; human
Facciuto F, Bugnon Valdano M, Marziali F, Massimi P, Banks L, Cavatorta A, et al. Human papillomavirus (HPV)-18 E6 oncoprotein interferes with the epithelial cell polarity Par3 protein. Mol Oncol. 2014;8:533-43 pubmed publisher
  • western blot; human
Cheng Y, Holloway M, Nguyen K, McCauley D, Landesman Y, Kauffman M, et al. XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer. Mol Cancer Ther. 2014;13:675-86 pubmed publisher
  • immunocytochemistry; human; 1:500
Polling S, Mok Y, Ramdzan Y, Turner B, Yerbury J, Hill A, et al. Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell. J Biol Chem. 2014;289:6669-80 pubmed publisher
  • western blot; human; 1:5000
O Sullivan R, Arnoult N, Lackner D, Oganesian L, Haggblom C, Corpet A, et al. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat Struct Mol Biol. 2014;21:167-74 pubmed publisher
  • immunocytochemistry; human
Nachbar J, Lázaro Diéguez F, Prekeris R, Cohen D, Müsch A. KIFC3 promotes mitotic progression and integrity of the central spindle in cytokinesis. Cell Cycle. 2014;13:426-33 pubmed publisher
  • immunoprecipitation; human
  • immunocytochemistry; human
Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed publisher
  • immunocytochemistry; human
Hashizume C, Moyori A, Kobayashi A, Yamakoshi N, Endo A, Wong R. Nucleoporin Nup62 maintains centrosome homeostasis. Cell Cycle. 2013;12:3804-16 pubmed publisher
  • immunocytochemistry; human; fig 3a
Zhang Y, Seo S, Bhattarai S, Bugge K, Searby C, Zhang Q, et al. BBS mutations modify phenotypic expression of CEP290-related ciliopathies. Hum Mol Genet. 2014;23:40-51 pubmed publisher
  • western blot; human; fig 5
Dai J, Brooks Y, Lefort K, Getsios S, Dotto G. The retinoid-related orphan receptor ROR? promotes keratinocyte differentiation via FOXN1. PLoS ONE. 2013;8:e70392 pubmed publisher
  • immunocytochemistry; human
Boutros R, Mondesert O, Lorenzo C, Astuti P, McArthur G, Chircop M, et al. CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci. PLoS ONE. 2013;8:e67822 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000
Willaredt M, Gorgas K, Gardner H, Tucker K. Multiple essential roles for primary cilia in heart development. Cilia. 2012;1:23 pubmed publisher
  • western blot; human
Koreishi M, Yu S, Oda M, Honjo Y, Satoh A. CK2 phosphorylates Sec31 and regulates ER-To-Golgi trafficking. PLoS ONE. 2013;8:e54382 pubmed publisher
  • immunocytochemistry; chicken; 1:150
Wang Y, Dantas T, Lalor P, Dockery P, Morrison C. Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response. Cell Cycle. 2013;12:635-46 pubmed publisher
  • immunocytochemistry; mouse
Zimmermann M, Lottersberger F, Buonomo S, Sfeir A, de Lange T. 53BP1 regulates DSB repair using Rif1 to control 5' end resection. Science. 2013;339:700-4 pubmed publisher
  • western blot; human
Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed publisher
  • immunocytochemistry; human; 1:500
Conroy P, Saladino C, Dantas T, Lalor P, Dockery P, Morrison C. C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis. Cell Cycle. 2012;11:3769-78 pubmed publisher
  • immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human
Pakala S, Nair V, Reddy S, Kumar R. Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localization. J Biol Chem. 2012;287:40560-9 pubmed publisher
  • immunocytochemistry; human
Ma M, Chircop M. SNX9, SNX18 and SNX33 are required for progression through and completion of mitosis. J Cell Sci. 2012;125:4372-82 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 4
Reboutier D, Troadec M, Cremet J, Fukasawa K, Prigent C. Nucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89. J Cell Biol. 2012;197:19-26 pubmed publisher
  • western blot; human
Chen Y, Fang S, Yeh P, Yang H, Chen S, Chang C, et al. The C-terminus of PARK2 is required for its self-interaction, solubility and role in the spindle assembly checkpoint. Biochim Biophys Acta. 2012;1822:573-80 pubmed publisher
Quan M, Oh Y, Cho S, Kim J, Moon H. Polo-Like Kinase 1 Regulates Chromosomal Instability and Paclitaxel Resistance in Breast Cancer Cells. J Breast Cancer. 2022;25:178-192 pubmed publisher
Garcia H, Serafin A, Silbermann F, Porée E, Viau A, Mahaut C, et al. Agonists of prostaglandin E2 receptors as potential first in class treatment for nephronophthisis and related ciliopathies. Proc Natl Acad Sci U S A. 2022;119:e2115960119 pubmed publisher
Kuang W, Jin H, Yang F, Chen X, Liu J, Li T, et al. ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis. Cell Discov. 2022;8:25 pubmed publisher
Shahi A, Kahle J, Hopkins C, Diakonova M. The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification. PLoS ONE. 2022;17:e0261098 pubmed publisher
Boi D, Souvalidou F, Capelli D, Polverino F, Marini G, Montanari R, et al. PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc. Int J Mol Sci. 2021;22: pubmed publisher
Batenburg N, Mersaoui S, Walker J, Coulombe Y, Hammond Martel I, Wurtele H, et al. Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells. Nucleic Acids Res. 2021;49:12836-12854 pubmed publisher
Alzyoud E, Vedelek V, Réthi Nagy Z, Lipinszki Z, Sinka R. Microtubule Organizing Centers Contain Testis-Specific γ-TuRC Proteins in Spermatids of Drosophila. Front Cell Dev Biol. 2021;9:727264 pubmed publisher
Poźniak M, Porębska N, Jastrzębski K, Krzyścik M, Kucińska M, Zarzycka W, et al. Modular self-assembly system for development of oligomeric, highly internalizing and potent cytotoxic conjugates targeting fibroblast growth factor receptors. J Biomed Sci. 2021;28:69 pubmed publisher
de Krijger I, Föhr B, Pérez S, Vincendeau E, Serrat J, Thouin A, et al. MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair. Nat Commun. 2021;12:5421 pubmed publisher
Hong J, Kim K, Park S, Bok J, Seo J, Moon S. Differential Roles of Tubby Family Proteins in Ciliary Formation and Trafficking. Mol Cells. 2021;44:591-601 pubmed publisher
Rasamizafy S, Delsert C, Rabeharivelo G, Cau J, Morin N, Van Dijk J. Mitotic Acetylation of Microtubules Promotes Centrosomal PLK1 Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis. Cells. 2021;10: pubmed publisher
Hwang S, Somatilaka B, White K, Mukhopadhyay S. Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner. elife. 2021;10: pubmed publisher
Hoque M, Chen D, Hess R, Li F, Takemaru K. CEP164 is essential for efferent duct multiciliogenesis and male fertility. Reproduction. 2021;162:129-139 pubmed publisher
Montavon T, Baldaccini M, Lefevre M, Girardi E, Chane Woon Ming B, Messmer M, et al. Human DICER helicase domain recruits PKR and modulates its antiviral activity. PLoS Pathog. 2021;17:e1009549 pubmed publisher
Bowman S, Le L, Zhu Y, Harper D, Sitaram A, Theos A, et al. A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers. J Cell Biol. 2021;220: pubmed publisher
Buglak D, Kushner E, Marvin A, Davis K, Bautch V. Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions. Angiogenesis. 2020;23:567-575 pubmed publisher
Kehl A, Göser V, Reuter T, Liss V, Franke M, John C, et al. A trafficome-wide RNAi screen reveals deployment of early and late secretory host proteins and the entire late endo-/lysosomal vesicle fusion machinery by intracellular Salmonella. PLoS Pathog. 2020;16:e1008220 pubmed publisher
Wigington C, Roy J, Damle N, Yadav V, Blikstad C, Resch E, et al. Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling. Mol Cell. 2020;79:342-358.e12 pubmed publisher
Agarwal S, Ganesh S. Perinuclear mitochondrial clustering, increased ROS levels, and HIF1 are required for the activation of HSF1 by heat stress. J Cell Sci. 2020;133: pubmed publisher
Guillen R, Beckley J, Chen J, Gould K. CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1. Sci Rep. 2020;10:6797 pubmed publisher
Venugopal N, Ghosh A, Gala H, Aloysius A, Vyas N, Dhawan J. The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts. BMC Mol Cell Biol. 2020;21:25 pubmed publisher
Au F, Hau B, Qi R. Nek2-mediated GAS2L1 phosphorylation and centrosome-linker disassembly induce centrosome disjunction. J Cell Biol. 2020;219: pubmed publisher
Dizanzo M, Marziali F, Brunet Avalos C, Bugnon Valdano M, Leiva S, Cavatorta A, et al. HPV E6 and E7 oncoproteins cooperatively alter the expression of Disc Large 1 polarity protein in epithelial cells. BMC Cancer. 2020;20:293 pubmed publisher
Viol L, Hata S, Pastor Peidro A, Neuner A, Murke F, Wuchter P, et al. Nek2 kinase displaces distal appendages from the mother centriole prior to mitosis. J Cell Biol. 2020;219: pubmed publisher
Sasaki Takahashi N, Shinohara H, Shioda S, Seki T. The polarity and properties of radial glia-like neural stem cells are altered by seizures with status epilepticus: Study using an improved mouse pilocarpine model of epilepsy. Hippocampus. 2020;30:250-262 pubmed publisher
Yang Y, Liu X, Li S, Chen Y, Zhao Y, Wei Y, et al. Genome-scale CRISPR screening for potential targets of ginsenoside compound K. Cell Death Dis. 2020;11:39 pubmed publisher
Cho B, Song S, Axelrod J. Prickle isoforms determine handedness of helical morphogenesis. elife. 2020;9: pubmed publisher
Alfaro Aco R, Thawani A, Petry S. Biochemical reconstitution of branching microtubule nucleation. elife. 2020;9: pubmed publisher
Mei J, Kong H, Zhao Z, Chen Z, Wang Y, Yang J. Shufengjiedu capsules protect against neuronal loss in olfactory epithelium and lung injury by enhancing autophagy in rats with allergic rhinitis. Biosci Trends. 2020;13:530-538 pubmed publisher
Vrenken K, Vervoort B, van Ingen Schenau D, Derks Y, van Emst L, Grytsenko P, et al. The transcriptional repressor SNAI2 impairs neuroblastoma differentiation and inhibits response to retinoic acid therapy. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165644 pubmed publisher
Samaranayake G, Troccoli C, Zhang L, Huynh M, Jayaraj C, Ji D, et al. The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors. Mol Cancer Ther. 2020;19:432-446 pubmed publisher
Misrani A, Tabassum S, Wang M, Chen J, Yang L, Long C. Citalopram prevents sleep-deprivation-induced reduction in CaMKII-CREB-BDNF signaling in mouse prefrontal cortex. Brain Res Bull. 2020;155:11-18 pubmed publisher
Distasio A, Paulding D, Chaturvedi P, Stottmann R. Nubp2 is required for cranial neural crest survival in the mouse. Dev Biol. 2020;458:189-199 pubmed publisher
Mugahid D, Sengul T, You X, Wang Y, Steil L, Bergmann N, et al. Proteomic and Transcriptomic Changes in Hibernating Grizzly Bears Reveal Metabolic and Signaling Pathways that Protect against Muscle Atrophy. Sci Rep. 2019;9:19976 pubmed publisher
Lorenzon I, Pellarin I, Pellizzari I, D Andrea S, Belletti B, Sonego M, et al. Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells. Cells. 2019;9: pubmed publisher
Moreno Felici J, Hyroššová P, Aragó M, Rodríguez Arévalo S, Garcia Roves P, Escolano C, et al. Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca2. Cells. 2019;9: pubmed publisher
Volta F, Scerbo M, Seelig A, Wagner R, O Brien N, Gerst F, et al. Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing. Nat Commun. 2019;10:5686 pubmed publisher
Bolderson E, Burgess J, Li J, Gandhi N, Boucher D, Croft L, et al. Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage. Nat Commun. 2019;10:5501 pubmed publisher
Shu S, Iimori M, Wakasa T, Ando K, Saeki H, Oda Y, et al. The balance of forces generated by kinesins controls spindle polarity and chromosomal heterogeneity in tetraploid cells. J Cell Sci. 2019;132: pubmed publisher
Gwon D, Hong J, Jang C. c-Cbl Acts as an E3 Ligase Against DDA3 for Spindle Dynamics and Centriole Duplication during Mitosis. Mol Cells. 2019;42:840-849 pubmed publisher
Randzavola L, Strege K, Juzans M, Asano Y, Stinchcombe J, Gawden Bone C, et al. Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019;129:5600-5614 pubmed publisher
Nano M, Gemble S, Simon A, Pennetier C, Fraisier V, Marthiens V, et al. Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells. Curr Biol. 2019;29:3937-3945.e7 pubmed publisher
Bueno M, Jimenez Renard V, Samino S, Capellades J, Junza A, López Rodríguez M, et al. Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells. Nat Commun. 2019;10:5011 pubmed publisher
Dudka D, Castrogiovanni C, Liaudet N, Vassal H, Meraldi P. Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics. Curr Biol. 2019;29:3563-3578.e6 pubmed publisher
Kumari A, Srivastava S, Manne R, Sisodiya S, Santra M, Guchhait S, et al. C12, a combretastatin-A4 analog, exerts anticancer activity by targeting microtubules. Biochem Pharmacol. 2019;170:113663 pubmed publisher
Conkar D, Bayraktar H, Firat Karalar E. Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors. Sci Rep. 2019;9:14250 pubmed publisher
Nachmani D, Bothmer A, Grisendi S, Mele A, Bothmer D, Lee J, et al. Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita. Nat Genet. 2019;51:1518-1529 pubmed publisher
Kasurinen A, Gramolelli S, Hagstrom J, Laitinen A, Kokkola A, Miki Y, et al. High tissue MMP14 expression predicts worse survival in gastric cancer, particularly with a low PROX1. Cancer Med. 2019;8:6995-7005 pubmed publisher
Zhou H, Zheng T, Wang T, Li Q, Wang F, Liang X, et al. CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment. BMC Biol. 2019;17:73 pubmed publisher
Hu D, Jasper H. Control of Intestinal Cell Fate by Dynamic Mitotic Spindle Repositioning Influences Epithelial Homeostasis and Longevity. Cell Rep. 2019;28:2807-2823.e5 pubmed publisher
Batenburg N, Walker J, Coulombe Y, Sherker A, Masson J, Zhu X. CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection. Nucleic Acids Res. 2019;47:10678-10692 pubmed publisher
Clarke S, Thompson L, Dandekar E, Srinivasan A, Montgomery M. Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism. Nutrients. 2019;11: pubmed publisher
Walker R, Keynton J, Grimes D, Sreekumar V, Williams D, Esapa C, et al. Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model. Nat Commun. 2019;10:4072 pubmed publisher
Wang M, Nagle R, Knudsen B, Cress A, Rogers G. Centrosome loss results in an unstable genome and malignant prostate tumors. Oncogene. 2019;: pubmed publisher
Morra F, Merolla F, D Abbiero D, Ilardi G, Campione S, Monaco R, et al. Analysis of CCDC6 as a novel biomarker for the clinical use of PARP1 inhibitors in malignant pleural mesothelioma. Lung Cancer. 2019;135:56-65 pubmed publisher
Frikstad K, Molinari E, Thoresen M, Ramsbottom S, Hughes F, Letteboer S, et al. A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling. Cell Rep. 2019;28:1907-1922.e6 pubmed publisher
Muñoz Estrada J, Ferland R. Ahi1 promotes Arl13b ciliary recruitment, regulates Arl13b stability and is required for normal cell migration. J Cell Sci. 2019;132: pubmed publisher
Uzquiano A, Cifuentes Diaz C, Jabali A, Romero D, Houllier A, Dingli F, et al. Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia. Cell Rep. 2019;28:1596-1611.e10 pubmed publisher
Luczak M, Krawic C, Zhitkovich A. p53 activation by Cr(VI): a transcriptionally limited response induced by ATR kinase in S-phase. Toxicol Sci. 2019;: pubmed publisher
Hartono -, Hazawa M, Lim K, Dewi F, Kobayashi A, Wong R. Nucleoporin Nup58 localizes to centrosomes and mid-bodies during mitosis. Cell Div. 2019;14:7 pubmed publisher
Jo K, Jaiswal A, Khanal S, Fishman E, Curry A, Avidor Reiss T. Poc1B and Sas-6 Function Together during the Atypical Centriole Formation in Drosophila melanogaster. Cells. 2019;8: pubmed publisher
Zhen Y, Spangenberg H, Munson M, Brech A, Schink K, Tan K, et al. ESCRT-mediated phagophore sealing during mitophagy. Autophagy. 2019;:1-16 pubmed publisher
Cabrera E, Raninga P, Khanna K, Freire R. GSK3-β Stimulates Claspin Degradation via β-TrCP Ubiquitin Ligase and Alters Cancer Cell Survival. Cancers (Basel). 2019;11: pubmed publisher
Aly M, Ramdzan Z, Nagata Y, Balasubramanian S, Hosono N, Makishima H, et al. Distinct clinical and biological implications of CUX1 in myeloid neoplasms. Blood Adv. 2019;3:2164-2178 pubmed publisher
Han Y, Chen Z, Shang Y, Yan W, Wu B, Li C. Cordycepin improves behavioral-LTP and dendritic structure in hippocampal CA1 area of rats. J Neurochem. 2019;151:79-90 pubmed publisher
Leong S, Lynch E, Zou J, Tay Y, Borek W, Tuijtel M, et al. Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1. Curr Biol. 2019;29:2199-2207.e10 pubmed publisher
Sneeggen M, Pedersen N, Campsteijn C, Haugsten E, Stenmark H, Schink K. WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling. Nat Commun. 2019;10:2850 pubmed publisher
Kucińska M, Porębska N, Lampart A, Latko M, Knapik A, Zakrzewska M, et al. Differential regulation of fibroblast growth factor receptor 1 trafficking and function by extracellular galectins. Cell Commun Signal. 2019;17:65 pubmed publisher
Walia V, Cuenca A, Vetter M, Insinna C, Perera S, Lu Q, et al. Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis. Dev Cell. 2019;: pubmed publisher
Szybowska P, Kostas M, Wesche J, Wiedlocha A, Haugsten E. Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway. Cells. 2019;8: pubmed publisher
Luo Y, Barrios Rodiles M, Gupta G, Zhang Y, Ogunjimi A, Bashkurov M, et al. Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility. Nat Commun. 2019;10:2356 pubmed publisher
Fang C, Kuo H, Hsu S, Yih L. HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes. Cell Div. 2019;14:4 pubmed publisher
Press M, Xie B, Davenport S, Zhou Y, Guzman R, Nolan G, et al. Role for polo-like kinase 4 in mediation of cytokinesis. Proc Natl Acad Sci U S A. 2019;116:11309-11318 pubmed publisher
van Dam T, Kennedy J, van der Lee R, de Vrieze E, Wunderlich K, Rix S, et al. CiliaCarta: An integrated and validated compendium of ciliary genes. PLoS ONE. 2019;14:e0216705 pubmed publisher
Nakajima Y, Lee Z, McKinney S, Swanson S, Florens L, Gibson M. Junctional tumor suppressors interact with 14-3-3 proteins to control planar spindle alignment. J Cell Biol. 2019;218:1824-1838 pubmed publisher
Ivanova E, Gilet J, Sulimenko V, Duchon A, Rudolf G, Runge K, et al. TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis. Nat Commun. 2019;10:2129 pubmed publisher
D Angelo D, Mussnich P, Sepe R, Raia M, Del Vecchio L, Cappabianca P, et al. RPSAP52 lncRNA is overexpressed in pituitary tumors and promotes cell proliferation by acting as miRNA sponge for HMGA proteins. J Mol Med (Berl). 2019;97:1019-1032 pubmed publisher
Wirth M, Zhang W, Razi M, Nyoni L, Joshi D, O Reilly N, et al. Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins. Nat Commun. 2019;10:2055 pubmed publisher
Labelle Dumais C, Schuitema V, Hayashi G, Hoff K, Gong W, Dao D, et al. COL4A1 Mutations Cause Neuromuscular Disease with Tissue-Specific Mechanistic Heterogeneity. Am J Hum Genet. 2019;104:847-860 pubmed publisher
Schlimpert M, Lagies S, Muller B, Budnyk V, Blanz K, Walz G, et al. Metabolic perturbations caused by depletion of nephronophthisis factor Anks6 in mIMCD3 cells. Metabolomics. 2019;15:71 pubmed publisher
Odabasi E, Gül S, Kavakli I, Firat Karalar E. Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation. EMBO Rep. 2019;20: pubmed publisher
Berge U, Bochenek D, Schnabel R, Wehling A, Schroeder T, Stadler T, et al. Asymmetric division events promote variability in cell cycle duration in animal cells and Escherichia coli. Nat Commun. 2019;10:1901 pubmed publisher
Zakrzewska M, Opaliński L, Haugsten E, Otlewski J, Wiedlocha A. Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling. Int J Mol Sci. 2019;20: pubmed publisher
Chiodi I, Picco G, Martino C, Mondello C. Cellular response to glutamine and/or glucose deprivation in in vitro transformed human fibroblasts. Oncol Rep. 2019;41:3555-3564 pubmed publisher
Khare S, Shetty A, Biradar R, Patta I, Chen Z, Sathe A, et al. NF-κB Signaling and IL-4 Signaling Regulate SATB1 Expression via Alternative Promoter Usage During Th2 Differentiation. Front Immunol. 2019;10:667 pubmed publisher
Lee K, Jeong J, An Y, Lee J, Yim H. FGF11 influences 3T3-L1 preadipocyte differentiation by modulating the expression of PPARγ regulators. FEBS Open Bio. 2019;9:769-780 pubmed publisher
Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, et al. The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS. Front Genet. 2019;10:249 pubmed publisher
Klebanovych A, Sladkova V, Sulimenko T, Vosecká V, Capek M, Dráberová E, et al. Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1. Cells. 2019;8: pubmed publisher
Lipok M, Szlachcic A, Kindela K, Czyrek A, Otlewski J. Identification of a peptide antagonist of the FGF1-FGFR1 signaling axis by phage display selection. FEBS Open Bio. 2019;9:914-924 pubmed publisher
Hauge S, Macurek L, Syljuåsen R. p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775. Cell Cycle. 2019;18:834-847 pubmed publisher
Ivanova I, Arulanantham S, Barr K, Cepeda M, Parkins K, Hamilton A, et al. Targeting FER Kinase Inhibits Melanoma Growth and Metastasis. Cancers (Basel). 2019;11: pubmed publisher
Zhan Z, Song L, Zhang W, Gu H, Cheng H, Zhang Y, et al. Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability. Cell Death Dis. 2019;10:271 pubmed publisher
Cruz Bermúdez A, Laza Briviesca R, Vicente Blanco R, García Grande A, Coronado M, Laine Menéndez S, et al. Cisplatin resistance involves a metabolic reprogramming through ROS and PGC-1α in NSCLC which can be overcome by OXPHOS inhibition. Free Radic Biol Med. 2019;135:167-181 pubmed publisher
Aziz K, Limzerwala J, Sturmlechner I, Hurley E, Zhang C, Jeganathan K, et al. Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice. Gastroenterology. 2019;: pubmed publisher
Tabassum S, Misrani A, Tang B, Chen J, Yang L, Long C. Jujuboside A prevents sleep loss-induced disturbance of hippocampal neuronal excitability and memory impairment in young APP/PS1 mice. Sci Rep. 2019;9:4512 pubmed publisher
Freitas Andrade M, Wang N, Bechberger J, De Bock M, Lampe P, Leybaert L, et al. Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke. J Exp Med. 2019;: pubmed publisher
Ortiz Álvarez G, Daclin M, Shihavuddin A, Lansade P, Fortoul A, Faucourt M, et al. Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members. Neuron. 2019;102:159-172.e7 pubmed publisher
Shah A, Melhuish T, Fox T, Frierson H, Wotton D. TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth. Genes Dev. 2019;33:388-402 pubmed publisher
Hodge B, Zhang X, Gutierrez Monreal M, Cao Y, Hammers D, Yao Z, et al. MYOD1 functions as a clock amplifier as well as a critical co-factor for downstream circadian gene expression in muscle. elife. 2019;8: pubmed publisher
Izumi H, Li Y, Shibaki M, Mori D, Yasunami M, Sato S, et al. Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region. Sci Rep. 2019;9:2236 pubmed publisher
Kunova Bosakova M, Nita A, Gregor T, Varecha M, Gudernová I, Fafilek B, et al. Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Rangel L, Bernabé Rubio M, Fernández Barrera J, Casares Arias J, Millan J, Alonso M, et al. Caveolin-1α regulates primary cilium length by controlling RhoA GTPase activity. Sci Rep. 2019;9:1116 pubmed publisher
Noguchi S, Honda S, Saitoh T, Matsumura H, Nishimura E, Akira S, et al. Beclin 1 regulates recycling endosome and is required for skin development in mice. Commun Biol. 2019;2:37 pubmed publisher
Insinna C, Lu Q, Teixeira I, Harned A, Semler E, Stauffer J, et al. Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. Nat Commun. 2019;10:428 pubmed publisher
Zhao Y, Feng Z, Zhang Y, Sun Y, Chen Y, Liu X, et al. Gain-of-Function Mutations of SLC16A11 Contribute to the Pathogenesis of Type 2 Diabetes. Cell Rep. 2019;26:884-892.e4 pubmed publisher
Patron L, Nagatomo K, Eves D, Imad M, Young K, Torvund M, et al. Cul4 ubiquitin ligase cofactor DCAF12 promotes neurotransmitter release and homeostatic plasticity. J Cell Biol. 2019;218:993-1010 pubmed publisher
Nagano T, Yamao S, Terachi A, Yarimizu H, Itoh H, Katasho R, et al. d-amino acid oxidase promotes cellular senescence via the production of reactive oxygen species. Life Sci Alliance. 2019;2: pubmed publisher
Doi N, Kunimatsu Y, Fujiura K, Togari H, Minagi K, Nakaoji K, et al. RhoGDIβ affects HeLa cell spindle orientation following UVC irradiation. J Cell Physiol. 2019;: pubmed publisher
Rosen J, Azevedo M, Soffar D, Boyko V, Brendel M, Schulman V, et al. The Drosophila Ninein homologue Bsg25D cooperates with Ensconsin in myonuclear positioning. J Cell Biol. 2019;218:524-540 pubmed publisher
Chen C, Xu Z, Zhang T, Lin L, Lu M, Xie C, et al. Cep85 Relays Plk1 Activity to Phosphorylated Nek2A for Its Timely Activation in Centrosome Disjunction. iScience. 2019;11:114-133 pubmed publisher
Velázquez Avila M, Balandrán J, Ramírez Ramírez D, Velázquez Avila M, Sandoval A, Felipe López A, et al. High cortactin expression in B-cell acute lymphoblastic leukemia is associated with increased transendothelial migration and bone marrow relapse. Leukemia. 2019;33:1337-1348 pubmed publisher
Tu H, Qin X, Liu Z, Song Z, Hu H, Zhang Y, et al. Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis. Nat Commun. 2018;9:5277 pubmed publisher
Ling H, Peng L, Wang J, Rahhal R, Seto E. Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication. Cell Rep. 2018;25:2851-2865.e3 pubmed publisher
Karole A, Chodisetty S, Ali A, Kumari N, Tyagi S. Novel sub-cellular localizations and intra-molecular interactions may define new functions of Mixed Lineage Leukemia protein. Cell Cycle. 2018;17:2684-2696 pubmed publisher
Ferreira R, Pakula G, Klaeylé L, Fukui H, Vilfan A, Supatto W, et al. Chiral Cilia Orientation in the Left-Right Organizer. Cell Rep. 2018;25:2008-2016.e4 pubmed publisher
Walch L, Pellier E, Leng W, Lakisic G, Gautreau A, Contremoulins V, et al. GBF1 and Arf1 interact with Miro and regulate mitochondrial positioning within cells. Sci Rep. 2018;8:17121 pubmed publisher
Title A, Hong S, Pires N, Hasenöhrl L, Godbersen S, Stokar Regenscheit N, et al. Genetic dissection of the miR-200-Zeb1 axis reveals its importance in tumor differentiation and invasion. Nat Commun. 2018;9:4671 pubmed publisher
Xia Y, Huang N, Chen Z, Li F, Fan G, Ma D, et al. CCDC102B functions in centrosome linker assembly and centrosome cohesion. J Cell Sci. 2018;131: pubmed publisher
Shakya S, Sharma P, Bhatt A, Jani R, Delevoye C, Setty S. Rab22A recruits BLOC-1 and BLOC-2 to promote the biogenesis of recycling endosomes. EMBO Rep. 2018;19: pubmed publisher
Kulkarni S, Khokha M. WDR5 regulates left-right patterning via chromatin-dependent and -independent functions. Development. 2018;145: pubmed publisher
Bärenz F, Kschonsak Y, Meyer A, Jafarpour A, Lorenz H, Hoffmann I. Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry. Mol Biol Cell. 2018;:mbcE18020115 pubmed publisher
Yan X, Wang Z, Bishop C, Weitkunat K, Feng X, Tarbier M, et al. Control of hepatic gluconeogenesis by Argonaute2. Mol Metab. 2018;18:15-24 pubmed publisher
Chondrou V, Trochoutsou K, Panayides A, Efthimiou M, Stephanou G, Demopoulos N. Combined study on clastogenic, aneugenic and apoptotic properties of doxorubicin in human cells in vitro. J Biol Res (Thessalon). 2018;25:17 pubmed publisher
Casar Tena T, Maerz L, Szafranski K, Groth M, Blätte T, Donow C, et al. Resting cells rely on the DNA helicase component MCM2 to build cilia. Nucleic Acids Res. 2019;47:134-151 pubmed publisher
Benedict B, van Harn T, Dekker M, Hermsen S, Küçükosmanoglu A, Pieters W, et al. Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells. elife. 2018;7: pubmed publisher
Xu Y, Zhang S, Zheng H. The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau). Autophagy. 2019;15:583-598 pubmed publisher
Lindström L, Li T, Malycheva D, Kancharla A, Nilsson H, Vishnu N, et al. The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization. Commun Biol. 2018;1:37 pubmed publisher
Yang K, Tylkowski M, Huber D, Contreras C, Hoyer Fender S. ODF2 maintains centrosome cohesion by restricting β-catenin accumulation. J Cell Sci. 2018;131: pubmed publisher
Montenegro Gouveia S, Zitouni S, Kong D, Duarte P, Ferreira Gomes B, Sousa A, et al. PLK4 is a microtubule-associated protein that self-assembles promoting de novo MTOC formation. J Cell Sci. 2018;132: pubmed publisher
Gavilan M, Gandolfo P, Balestra F, Arias F, Bornens M, Rios R. The dual role of the centrosome in organizing the microtubule network in interphase. EMBO Rep. 2018;19: pubmed publisher
Weyergang A, Fremstedal A, Skarpen E, Peng Q, Mohamedali K, Eng M, et al. Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy. J Control Release. 2018;288:161-172 pubmed publisher
Kulkarni S, Griffin J, Date P, Liem K, Khokha M. WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation. Dev Cell. 2018;46:595-610.e3 pubmed publisher
Yakulov T, Todkar A, Slanchev K, Wiegel J, Bona A, Groß M, et al. CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury. Nat Commun. 2018;9:3660 pubmed publisher
Zhou X, Xiao C, Li Y, Shang Y, Yin D, Li S, et al. Mid1ip1b modulates apical reorientation of non-centrosomal microtubule organizing center in epithelial cells. J Genet Genomics. 2018;45:433-442 pubmed publisher
Nag S, Rani S, Mahanty S, Bissig C, Arora P, Azevedo C, et al. Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles. J Cell Sci. 2018;131: pubmed publisher
Yeung M, Jia L, Yip C, Chan J, Teng J, Chan K, et al. Human tryptophanyl-tRNA synthetase is an IFN-γ-inducible entry factor for Enterovirus. J Clin Invest. 2018;128:5163-5177 pubmed publisher
Knouse K, Lopez K, Bachofner M, Amon A. Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture. Cell. 2018;175:200-211.e13 pubmed publisher
Gillman A, Parker G, Allday M, Bazot Q. Epstein-Barr Virus Nuclear Antigen 3C Inhibits Expression of COBLL1 and the ADAM28-ADAMDEC1 Locus via Interaction with the Histone Lysine Demethylase KDM2B. J Virol. 2018;92: pubmed publisher
Kurtulmus B, Yuan C, Schuy J, Neuner A, Hata S, Kalamakis G, et al. LRRC45 contributes to early steps of axoneme extension. J Cell Sci. 2018;131: pubmed publisher
Warkocki Z, Krawczyk P, Adamska D, Bijata K, Garcia Perez J, Dziembowski A. Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. Cell. 2018;174:1537-1548.e29 pubmed publisher
Hoff S, Epting D, Falk N, Schroda S, Braun D, Halbritter J, et al. The nucleoside-diphosphate kinase NME3 associates with nephronophthisis proteins and is required for ciliary function during renal development. J Biol Chem. 2018;293:15243-15255 pubmed publisher
Kostas M, Lampart A, Bober J, Wiedlocha A, Tomala J, Krowarsch D, et al. Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation. J Mol Biol. 2018;430:4087-4101 pubmed publisher
Ovejero S, Ayala P, Malumbres M, Pimentel Muiños F, Bueno A, Sacristán M. Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1. Sci Rep. 2018;8:11871 pubmed publisher
Romé P, Ohkura H. A novel microtubule nucleation pathway for meiotic spindle assembly in oocytes. J Cell Biol. 2018;: pubmed publisher
Stonyte V, Boye E, Grallert B. Regulation of global translation during the cell cycle. J Cell Sci. 2018;131: pubmed publisher
de Carcer G, Venkateswaran S, Salgueiro L, El Bakkali A, Somogyi K, Rowald K, et al. Plk1 overexpression induces chromosomal instability and suppresses tumor development. Nat Commun. 2018;9:3012 pubmed publisher
Evangelista F, Maglott Roth A, Stierlé M, Brino L, Soutoglou E, Tora L. Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair. J Cell Biol. 2018;217:3382-3397 pubmed publisher
Aziz K, Sieben C, Jeganathan K, Hamada M, Davies B, Velasco R, et al. Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in Cep57 impairs tumor suppression. J Clin Invest. 2018;128:3517-3534 pubmed publisher
Sukhotnik I, Moati D, Shaoul R, Loberman B, Pollak Y, Schwartz B. Quercetin prevents small intestinal damage and enhances intestinal recovery during methotrexate-induced intestinal mucositis of rats. Food Nutr Res. 2018;62: pubmed publisher
Krzyścik M, Zakrzewska M, Sørensen V, Sokolowska Wedzina A, Lobocki M, Świderska K, et al. Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors. ACS Omega. 2017;2:3792-3805 pubmed publisher
Misrani A, Tabassum S, Chen X, Tan S, Wang J, Yang L, et al. Differential effects of citalopram on sleep-deprivation-induced depressive-like behavior and memory impairments in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2019;88:102-111 pubmed publisher
Muñoz Espín D, Rovira M, Galiana I, Giménez C, Lozano Torres B, Pàez Ribes M, et al. A versatile drug delivery system targeting senescent cells. EMBO Mol Med. 2018;10: pubmed publisher
Tovey C, Tubman C, Hamrud E, Zhu Z, Dyas A, Butterfield A, et al. ?-TuRC Heterogeneity Revealed by Analysis of Mozart1. Curr Biol. 2018;28:2314-2323.e6 pubmed publisher
Rozanska E, Czarnocka W, Baranowski Ł, Mielecki J, de Almeida Engler J, Sobczak M. Expression of both Arabidopsis γ-tubulin genes is essential for development of a functional syncytium induced by Heterodera schachtii. Plant Cell Rep. 2018;37:1279-1292 pubmed publisher
Roitenberg N, Bejerano Sagie M, Boocholez H, Moll L, Marques F, Golodetzki L, et al. Modulation of caveolae by insulin/IGF-1 signaling regulates aging of Caenorhabditis elegans. EMBO Rep. 2018;19: pubmed publisher
De Pasquale V, Sarogni P, Pistorio V, Cerulo G, Paladino S, Pavone L. Targeting Heparan Sulfate Proteoglycans as a Novel Therapeutic Strategy for Mucopolysaccharidoses. Mol Ther Methods Clin Dev. 2018;10:8-16 pubmed publisher
Matsumoto G, Inobe T, Amano T, Murai K, Nukina N, Mori N. N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression. Sci Rep. 2018;8:9585 pubmed publisher
Park S, Lim J, Ramakrishina S, Kim S, Kim W, Lee J, et al. Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination. Neuron. 2018;99:83-97.e7 pubmed publisher
Gramolelli S, Cheng J, Martínez Corral I, Vaha Koskela M, Elbasani E, Kaivanto E, et al. PROX1 is a transcriptional regulator of MMP14. Sci Rep. 2018;8:9531 pubmed publisher
Gorissen B, de Bruin A, Miranda Bedate A, Korthagen N, Wolschrijn C, de Vries T, et al. Hypoxia negatively affects senescence in osteoclasts and delays osteoclastogenesis. J Cell Physiol. 2018;234:414-426 pubmed publisher
Hsu W, Wang W, Lin W, Huang Y, Lai C, Liao J, et al. Adducin-1 is essential for spindle pole integrity through its interaction with TPX2. EMBO Rep. 2018;19: pubmed publisher
Funabashi T, Katoh Y, Okazaki M, Sugawa M, Nakayama K. Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis. J Cell Biol. 2018;217:2867-2876 pubmed publisher
Ganier O, Schnerch D, Nigg E. Structural centrosome aberrations sensitize polarized epithelia to basal cell extrusion. Open Biol. 2018;8: pubmed publisher
Kovacs L, Chao Chu J, Schneider S, Gottardo M, Tzolovsky G, Dzhindzhev N, et al. Gorab is a Golgi protein required for structure and duplication of Drosophila centrioles. Nat Genet. 2018;50:1021-1031 pubmed publisher
Mahuzier A, Shihavuddin A, Fournier C, Lansade P, Faucourt M, Menezes N, et al. Ependymal cilia beating induces an actin network to protect centrioles against shear stress. Nat Commun. 2018;9:2279 pubmed publisher
Song J, King M, Zhang R, Kadzik R, Thawani A, Petry S. Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules. J Cell Biol. 2018;217:2417-2428 pubmed publisher
Swaminathan A, Hassan Abdi R, Renault S, Siekierska A, Riché R, Liao M, et al. Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development. Curr Biol. 2018;28:1924-1937.e5 pubmed publisher
Takayama K, Muto A, Kikuchi Y. Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration. Sci Rep. 2018;8:8278 pubmed publisher
Visweshwaran S, Thomason P, Guerois R, Vacher S, Denisov E, Tashireva L, et al. The trimeric coiled-coil HSBP1 protein promotes WASH complex assembly at centrosomes. EMBO J. 2018;37: pubmed publisher
Canovas B, Igea A, Sartori A, Gomis R, Paull T, Isoda M, et al. Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells. Cancer Cell. 2018;33:1094-1110.e8 pubmed publisher
Brinkman E, Chen T, de Haas M, Holland H, Akhtar W, van Steensel B. Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks. Mol Cell. 2018;70:801-813.e6 pubmed publisher
Flor Parra I, Iglesias Romero A, Chang F. The XMAP215 Ortholog Alp14 Promotes Microtubule Nucleation in Fission Yeast. Curr Biol. 2018;28:1681-1691.e4 pubmed publisher
Li Q, Alsaidan O, Rai S, Wu M, Shen H, Beharry Z, et al. Stromal Gli signaling regulates the activity and differentiation of prostate stem and progenitor cells. J Biol Chem. 2018;293:10547-10560 pubmed publisher
Sanz Bravo A, Martin Esteban A, Kuiper J, García Peydró M, Barnea E, Admon A, et al. Allele-specific Alterations in the Peptidome Underlie the Joint Association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy. Mol Cell Proteomics. 2018;17:1564-1577 pubmed publisher
Kim J, Choi S, Lee S, Park K. Voltage-dependent Ca2+ channels promote branching morphogenesis of salivary glands by patterning differential growth. Sci Rep. 2018;8:7566 pubmed publisher
Alvarado Kristensson M. A simple and fast method for fixation of cultured cell lines that preserves cellular structures containing gamma-tubulin. MethodsX. 2018;5:227-233 pubmed publisher
Azizzadeh Pormehr L, Daftarian N, Ahmadian S, Rezaei Kanavi M, Ahmadieh H, Shafiezadeh M. Human organotypic retinal flat-mount culture (HORFC) as a model for retinitis pigmentosa11. J Cell Biochem. 2018;119:6775-6783 pubmed publisher
Shearer R, Frikstad K, McKenna J, McCloy R, Deng N, Burgess A, et al. The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia. Mol Biol Cell. 2018;29:1542-1554 pubmed publisher
Elmore Z, Guillen R, Gould K. The kinase domain of CK1 enzymes contains the localization cue essential for compartmentalized signaling at the spindle pole. Mol Biol Cell. 2018;29:1664-1674 pubmed publisher
Lopes C, Mesquita M, Cunha A, Cardoso J, Carapeta S, Laranjeira C, et al. Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis. J Cell Biol. 2018;217:2353-2363 pubmed publisher
Chen J, Castelvecchi G, Li Villarreal N, Raught B, Krezel A, McNeill H, et al. Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages. Dev Cell. 2018;45:376-391.e5 pubmed publisher
Wu D, Gu K, Yu J, Fu X, Wang X, Guo W, et al. Opposing roles of miR-294 and MBNL1/2 in shaping the gene regulatory network of embryonic stem cells. EMBO Rep. 2018;19: pubmed publisher
Hossain D, Ferreira Barbosa J, Cohen E, Tsang W. HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis. J Biol Chem. 2018;293:9448-9460 pubmed publisher
Bøe C, Håland T, Boye E, Syljuåsen R, Grallert B. A novel role for ATR/Rad3 in G1 phase. Sci Rep. 2018;8:6880 pubmed publisher
Guy J, Alexander Howden B, Fitzpatrick L, Desousa D, Koerner M, Selfridge J, et al. A mutation-led search for novel functional domains in MeCP2. Hum Mol Genet. 2018;27:2531-2545 pubmed publisher
Sepúlveda G, Antkowiak M, Brust Mascher I, Mahe K, Ou T, Castro N, et al. Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates. elife. 2018;7: pubmed publisher
Martin J, Mendonça L, Marusinec R, Zuczek J, Angert I, Blower R, et al. Critical Role of the Human T-Cell Leukemia Virus Type 1 Capsid N-Terminal Domain for Gag-Gag Interactions and Virus Particle Assembly. J Virol. 2018;92: pubmed publisher
Kuipers A, Middelbeek J, Vrenken K, Pérez González C, Poelmans G, Klarenbeek J, et al. TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4. Biochim Biophys Acta Mol Basis Dis. 2018;1864:2409-2419 pubmed publisher
Wiegering A, Dildrop R, Kalfhues L, Spychala A, Kuschel S, Lier J, et al. Cell type-specific regulation of ciliary transition zone assembly in vertebrates. EMBO J. 2018;37: pubmed publisher
Lee S, Sanchez Watts G, Krieger J, Pignalosa A, Norell P, Cortella A, et al. Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposity. Mol Metab. 2018;11:33-46 pubmed publisher
El Saafin F, Curry C, Ye T, Garnier J, Kolb Cheynel I, Stierlé M, et al. Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription. Hum Mol Genet. 2018;27:2171-2186 pubmed publisher
Pernas L, Bean C, Boothroyd J, Scorrano L. Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids. Cell Metab. 2018;27:886-897.e4 pubmed publisher
Yan S, Tu Z, Liu Z, Fan N, Yang H, Yang S, et al. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. Cell. 2018;173:989-1002.e13 pubmed publisher
Im M, Dagnino L. Protective role of integrin-linked kinase against oxidative stress and in maintenance of genomic integrity. Oncotarget. 2018;9:13637-13651 pubmed publisher
Ganier O, Schnerch D, Oertle P, Lim R, Plodinec M, Nigg E. Structural centrosome aberrations promote non-cell-autonomous invasiveness. EMBO J. 2018;37: pubmed publisher
Gurrapu S, Pupo E, Franzolin G, Lanzetti L, Tamagnone L. Sema4C/PlexinB2 signaling controls breast cancer cell growth, hormonal dependence and tumorigenic potential. Cell Death Differ. 2018;25:1259-1275 pubmed publisher
Martin M, Veloso A, Wu J, Katrukha E, Akhmanova A. Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules. elife. 2018;7: pubmed publisher
Swaminathan A, Bouffard M, Liao M, Ryan S, Callister J, Pickering Brown S, et al. Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model. Hum Mol Genet. 2018;27:1754-1762 pubmed publisher
Breun M, Schwerdtfeger A, Martellotta D, Kessler A, Perez J, Monoranu C, et al. CXCR4: A new player in vestibular schwannoma pathogenesis. Oncotarget. 2018;9:9940-9950 pubmed publisher
Larsson V, Jafferali M, Vijayaraghavan B, Figueroa R, Hallberg E. Mitotic spindle assembly and ?-tubulin localisation depend on the integral nuclear membrane protein Samp1. J Cell Sci. 2018;131: pubmed publisher
Tavano S, Taverna E, Kalebic N, Haffner C, Namba T, Dahl A, et al. Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7. Neuron. 2018;97:1299-1314.e8 pubmed publisher
Donohoe C, Csordás G, Correia A, Jindra M, Klein C, Habermann B, et al. Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture. PLoS Genet. 2018;14:e1007241 pubmed publisher
Hartley M, Eren R, Rossi M, Prevel F, Castiglioni P, Isorce N, et al. Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β. Microb Cell. 2018;5:137-149 pubmed publisher
Liu X, Wang Y, Liu F, Zhang M, Song H, Zhou B, et al. Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling. Sci Signal. 2018;11: pubmed publisher
Wang C, Li J, Takemaru K, Jiang X, Xu G, Wang B. Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse. Development. 2018;145: pubmed publisher
Ghézali G, Calvo C, Pillet L, Llense F, Ezan P, Pannasch U, et al. Connexin 30 controls astroglial polarization during postnatal brain development. Development. 2018;145: pubmed publisher
Hsu F, Spannl S, Ferguson C, Hyman A, Parton R, Zerial M. Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria. elife. 2018;7: pubmed publisher
Ott C, Nachmias D, Adar S, Jarnik M, Sherman S, Birnbaum R, et al. VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis. Sci Rep. 2018;8:3353 pubmed publisher
Fang C, Bian G, Ren P, Xiang J, Song J, Yu C, et al. S1P transporter SPNS2 regulates proper postnatal retinal morphogenesis. FASEB J. 2018;32:3597-3613 pubmed publisher
Li Q, Ingram L, Kim S, Beharry Z, Cooper J, Cai H. Paracrine Fibroblast Growth Factor Initiates Oncogenic Synergy with Epithelial FGFR/Src Transformation in Prostate Tumor Progression. Neoplasia. 2018;20:233-243 pubmed publisher
Sharma A, Quittner Strom E, Lee Y, Johnson J, Martin S, Yu X, et al. Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice. Cell Rep. 2018;22:1760-1773 pubmed publisher
Sharif A, Yu D, Loertscher S, Austin R, Nguyen K, Mathur P, et al. C8ORF37 Is Required for Photoreceptor Outer Segment Disc Morphogenesis by Maintaining Outer Segment Membrane Protein Homeostasis. J Neurosci. 2018;38:3160-3176 pubmed publisher
Roque H, Saurya S, Pratt M, Johnson E, Raff J. Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation. PLoS Genet. 2018;14:e1007198 pubmed publisher
Rai A, Singh P, Singh V, Kumar V, Mishra R, Thakur A, et al. Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux. Cell Death Dis. 2018;9:201 pubmed publisher
Kostas M, Haugsten E, Zhen Y, Sørensen V, Szybowska P, Fiorito E, et al. Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors. Mol Cell Proteomics. 2018;17:850-870 pubmed publisher
Bazot Q, Paschos K, Allday M. Epstein-Barr Virus (EBV) Latent Protein EBNA3A Directly Targets and Silences the STK39 Gene in B Cells Infected by EBV. J Virol. 2018;92: pubmed publisher
Bonello T, Perez Vale K, Sumigray K, Peifer M. Rap1 acts via multiple mechanisms to position Canoe and adherens junctions and mediate apical-basal polarity establishment. Development. 2018;145: pubmed publisher
Vidak S, Georgiou K, Fichtinger P, Naetar N, Dechat T, Foisner R. Nucleoplasmic lamins define growth-regulating functions of lamina-associated polypeptide 2α in progeria cells. J Cell Sci. 2018;131: pubmed publisher
Kunova Bosakova M, Varecha M, Hampl M, Durán I, Nita A, Buchtová M, et al. Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies. Hum Mol Genet. 2018;27:1093-1105 pubmed publisher
Lasar D, Rosenwald M, Kiehlmann E, Balaz M, Tall B, Opitz L, et al. Peroxisome Proliferator Activated Receptor Gamma Controls Mature Brown Adipocyte Inducibility through Glycerol Kinase. Cell Rep. 2018;22:760-773 pubmed publisher
Fernández Barrera J, Bernabé Rubio M, Casares Arias J, Rangel L, Fernández Martín L, Correas I, et al. The actin-MRTF-SRF transcriptional circuit controls tubulin acetylation via α-TAT1 gene expression. J Cell Biol. 2018;217:929-944 pubmed publisher
Quiroga Artigas G, Lapébie P, Leclère L, Takeda N, Deguchi R, Jekely G, et al. A gonad-expressed opsin mediates light-induced spawning in the jellyfish Clytia. elife. 2018;7: pubmed publisher
Imtiaz A, Belyantseva I, Beirl A, Fenollar Ferrer C, Bashir R, Bukhari I, et al. CDC14A phosphatase is essential for hearing and male fertility in mouse and human. Hum Mol Genet. 2018;27:780-798 pubmed publisher
Eibes S, Gallisà Suñé N, Rosas Salvans M, Martínez Delgado P, Vernos I, Roig J. Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown. Curr Biol. 2018;28:121-129.e4 pubmed publisher
Kim Y, Osborn D, Lee J, Araki M, Araki K, Mohun T, et al. WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome. EMBO Rep. 2018;19:269-289 pubmed publisher
Kitagawa M, Liao P, Lee K, Wong J, Shang S, Minami N, et al. Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality. Nat Commun. 2017;8:2200 pubmed publisher
Bizzotto S, Uzquiano A, Dingli F, Ershov D, Houllier A, Arras G, et al. Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex. Sci Rep. 2017;7:17308 pubmed publisher
He M, Ye W, Wang W, Sison E, Jan Y, Jan L. Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis. Proc Natl Acad Sci U S A. 2017;114:E11161-E11169 pubmed publisher
Yan X, Wang Z, Schmidt V, Gauert A, Willnow T, Heinig M, et al. Cadm2 regulates body weight and energy homeostasis in mice. Mol Metab. 2018;8:180-188 pubmed publisher
Advedissian T, Proux Gillardeaux V, Nkosi R, Peyret G, Nguyen T, Poirier F, et al. E-cadherin dynamics is regulated by galectin-7 at epithelial cell surface. Sci Rep. 2017;7:17086 pubmed publisher
Yang X, Wang Z, Li X, Liu B, Liu M, Liu L, et al. SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation. Cancer Res. 2018;78:372-386 pubmed publisher
Marziali F, Bugnon Valdano M, Brunet Avalos C, Moriena L, Cavatorta A, Gardiol D. Interference of HTLV-1 Tax Protein with Cell Polarity Regulators: Defining the Subcellular Localization of the Tax-DLG1 Interaction. Viruses. 2017;9: pubmed publisher
Simonetta M, de Krijger I, Serrat J, Moatti N, Fortunato D, Hoekman L, et al. H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2. Cell Cycle. 2017;:1-29 pubmed publisher
Hu C, Rai R, Huang C, Broton C, Long J, Xu Y, et al. Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex. Cell Res. 2017;27:1485-1502 pubmed publisher
Desgrange A, Heliot C, Skovorodkin I, Akram S, Heikkilä J, Ronkainen V, et al. HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis. Development. 2017;144:4704-4719 pubmed publisher
Clift D, McEwan W, Labzin L, Konieczny V, Mogessie B, James L, et al. A Method for the Acute and Rapid Degradation of Endogenous Proteins. Cell. 2017;171:1692-1706.e18 pubmed publisher
Rhys A, Monteiro P, Smith C, Vaghela M, Arnandis T, Kato T, et al. Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells. J Cell Biol. 2018;217:195-209 pubmed publisher
Nakamuta S, Yang Y, Wang C, Gallo N, Yu J, Tai Y, et al. Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. J Cell Biol. 2017;216:4313-4330 pubmed publisher
Broix L, Asselin L, Silva C, Ivanova E, Tilly P, Gilet J, et al. Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development. Hum Mol Genet. 2018;27:224-238 pubmed publisher
Mateos Gomez P, Kent T, Deng S, McDevitt S, Kashkina E, Hoang T, et al. The helicase domain of Pol? counteracts RPA to promote alt-NHEJ. Nat Struct Mol Biol. 2017;24:1116-1123 pubmed publisher
El Shamieh S, Méjécase C, Bertelli M, Terray A, Michiels C, Condroyer C, et al. Further Insights into the Ciliary Gene and Protein KIZ and Its Murine Ortholog PLK1S1 Mutated in Rod-Cone Dystrophy. Genes (Basel). 2017;8: pubmed publisher
El Kasmi I, Khadivjam B, Lackman M, Duron J, Bonneil E, Thibault P, et al. Extended Synaptotagmin 1 Interacts with Herpes Simplex Virus 1 Glycoprotein M and Negatively Modulates Virus-Induced Membrane Fusion. J Virol. 2018;92: pubmed publisher
Dubois F, Alpha K, Turner C. Paxillin regulates cell polarization and anterograde vesicle trafficking during cell migration. Mol Biol Cell. 2017;28:3815-3831 pubmed publisher
Martin L, Kaci N, Estibals V, Goudin N, Garfa Traoré M, Benoist Lasselin C, et al. Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia. Hum Mol Genet. 2018;27:1-13 pubmed publisher
Inoue Yamauchi A, Itagaki H, Oda H. Eicosapentaenoic acid attenuates obesity-related hepatocellular carcinogenesis. Carcinogenesis. 2017;: pubmed publisher
Kaur S, Ramdzan Z, Guiot M, Li L, Leduy L, Ramotar D, et al. CUX1 Stimulates APE1 Enzymatic Activity and Increases the Resistance of Glioblastoma Cells to the Mono-Alkylating Agent, Temozolomide. Neuro Oncol. 2017;: pubmed publisher
Ruiz M, Bégou M, Launay N, Ranea Robles P, Bianchi P, López Erauskin J, et al. OXIDATIVE STRESS AND MITOCHONDRIAL DYNAMICS MALFUNCTION ARE LINKED IN PELIZAEUS-MERZBACHER DISEASE. Brain Pathol. 2017;: pubmed publisher
Yukawa M, Kawakami T, Okazaki M, Kume K, Tang N, Toda T. A microtubule polymerase cooperates with the kinesin-6 motor and a microtubule cross-linker to promote bipolar spindle assembly in the absence of kinesin-5 and kinesin-14 in fission yeast. Mol Biol Cell. 2017;28:3647-3659 pubmed publisher
Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz Cortés T, Jove M, et al. Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. Aging Cell. 2017;16:1404-1413 pubmed publisher
Carroll T, Langlands A, Osborne J, Newton I, Appleton P, Näthke I. Interkinetic nuclear migration and basal tethering facilitates post-mitotic daughter separation in intestinal organoids. J Cell Sci. 2017;130:3862-3877 pubmed publisher
Miyamoto T, Akutsu S, Fukumitsu A, Morino H, Masatsuna Y, Hosoba K, et al. PLK1-mediated phosphorylation of WDR62/MCPH2 ensures proper mitotic spindle orientation. Hum Mol Genet. 2017;26:4429-4440 pubmed publisher
Bury L, Coelho P, Simeone A, Ferries S, Eyers C, Eyers P, et al. Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes. J Cell Biol. 2017;216:3571-3590 pubmed publisher
Arnoult N, Correia A, Ma J, Merlo A, Garcia Gomez S, Maric M, et al. Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN. Nature. 2017;549:548-552 pubmed publisher
King B, Kellner S, Eisenhauer P, Bruce E, Ziegler C, Zenklusen D, et al. Visualization of the lymphocytic choriomeningitis mammarenavirus (LCMV) genome reveals the early endosome as a possible site for genome replication and viral particle pre-assembly. J Gen Virol. 2017;: pubmed publisher
Hozumi S, Aoki S, Kikuchi Y. Nuclear movement regulated by non-Smad Nodal signaling via JNK is associated with Smad signaling during zebrafish endoderm specification. Development. 2017;144:4015-4025 pubmed publisher
Lu Y, Dai X, Zhang M, Miao Y, Zhou C, Cui Z, et al. Cohesin acetyltransferase Esco2 regulates SAC and kinetochore functions via maintaining H4K16 acetylation during mouse oocyte meiosis. Nucleic Acids Res. 2017;45:9388-9397 pubmed publisher
Nguyen H, Hinman M, Guo X, Sharma A, Arakawa H, Luo G, et al. Neurofibromatosis type 1 alternative splicing is a key regulator of Ras/ERK signaling and learning behaviors in mice. Hum Mol Genet. 2017;26:3797-3807 pubmed publisher
Hagopian J, Hamil A, van den Berg A, Meade B, Eguchi A, Palm Apergi C, et al. Induction of RNAi Responses by Short Left-Handed Hairpin RNAi Triggers. Nucleic Acid Ther. 2017;27:260-271 pubmed publisher
Richardson D, Gregor C, Winter F, Urban N, Sahl S, Willig K, et al. SRpHi ratiometric pH biosensors for super-resolution microscopy. Nat Commun. 2017;8:577 pubmed publisher
Windpassinger C, Piard J, Bonnard C, Alfadhel M, Lim S, Bisteau X, et al. CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays. Am J Hum Genet. 2017;101:391-403 pubmed publisher
Goodman L, Zallocchi M. Integrin α8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells. J Cell Sci. 2017;130:3698-3712 pubmed publisher
Takahara T, Inoue K, Arai Y, Kuwata K, Shibata H, Maki M. The calcium-binding protein ALG-2 regulates protein secretion and trafficking via interactions with MISSL and MAP1B proteins. J Biol Chem. 2017;292:17057-17072 pubmed publisher
Yang C, Wu J, de Heus C, Grigoriev I, Liv N, Yao Y, et al. EB1 and EB3 regulate microtubule minus end organization and Golgi morphology. J Cell Biol. 2017;216:3179-3198 pubmed publisher
di Pietro F, Valon L, Li Y, Goïame R, Genovesio A, Morin X. An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z ? as an Essential Regulator of Spindle Orientation. Curr Biol. 2017;27:2452-2464.e8 pubmed publisher
Wang Q, Lingel A, Geiser V, Kwapnoski Z, Zhang L. Tumor Suppressor p53 Stimulates the Expression of Epstein-Barr Virus Latent Membrane Protein 1. J Virol. 2017;91: pubmed publisher
Yoshida K, Imamura C, Hara K, Mochizuki M, Tanigawara Y. Effect of everolimus on the glucose metabolic pathway in mouse skeletal muscle cells (C2C12). Metabolomics. 2017;13:98 pubmed publisher
Govindarajalu G, Selvam M, Palchamy E, Baluchamy S. N-terminal truncations of human bHLH transcription factor Twist1 leads to the formation of aggresomes. Mol Cell Biochem. 2018;439:75-85 pubmed publisher
de Saram P, Iqbal A, Murdoch J, Wilkinson C. BCAP is a centriolar satellite protein and inhibitor of ciliogenesis. J Cell Sci. 2017;130:3360-3373 pubmed publisher
Opaliński Ł, Sokołowska Wędzina A, Szczepara M, Zakrzewska M, Otlewski J. Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity. Sci Rep. 2017;7:7121 pubmed publisher
Venkat S, Linstedt A. Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin. Mol Biol Cell. 2017;28:2569-2578 pubmed publisher
Krawic C, Luczak M, Zhitkovich A. Variation in Extracellular Detoxification Is a Link to Different Carcinogenicity among Chromates in Rodent and Human Lungs. Chem Res Toxicol. 2017;30:1720-1729 pubmed publisher
Shrestha R, Conti D, Tamura N, Braun D, Ramalingam R, Cieśliński K, et al. Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells. Nat Commun. 2017;8:150 pubmed publisher
Pae J, Cinalli R, Marzio A, Pagano M, Lehmann R. GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK. Dev Cell. 2017;42:130-142.e7 pubmed publisher
Ivovic A, Oprescu A, Koulajian K, Mori Y, Eversley J, Zhang L, et al. IKK? inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents. Diabetologia. 2017;60:2021-2032 pubmed publisher
Schive S, Mirlashari M, Hasvold G, Wang M, Josefsen D, Gullestad H, et al. Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo. Cell Med. 2017;9:103-116 pubmed publisher
Libé Philippot B, Michel V, Boutet de Monvel J, Le Gal S, Dupont T, Avan P, et al. Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction. Proc Natl Acad Sci U S A. 2017;114:7765-7774 pubmed publisher
Priya A, Sugatha J, Parveen S, Lacas Gervais S, Raj P, Gilleron J, et al. Essential and selective role of SNX12 in transport of endocytic and retrograde cargo. J Cell Sci. 2017;130:2707-2721 pubmed publisher
McHugh D, Caduff N, Barros M, Rämer P, Raykova A, Murer A, et al. Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression. Cell Host Microbe. 2017;22:61-73.e7 pubmed publisher
Glover J, Wells K, Matthäus F, Painter K, Ho W, Riddell J, et al. Hierarchical patterning modes orchestrate hair follicle morphogenesis. PLoS Biol. 2017;15:e2002117 pubmed publisher
Stopp S, Gründl M, Fackler M, Malkmus J, Leone M, Naumann R, et al. Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci U S A. 2017;114:8029-8034 pubmed publisher
Saadaoui M, Konno D, Loulier K, Goïame R, Jadhav V, Mapelli M, et al. Loss of the canonical spindle orientation function in the Pins/LGN homolog AGS3. EMBO Rep. 2017;18:1509-1520 pubmed publisher
Hsu J, Jhang Y, Cheng P, Chang Y, Mao S, Yang H, et al. The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models. Front Mol Neurosci. 2017;10:196 pubmed publisher
Barandalla M, Shi H, Xiao H, Colleoni S, Galli C, Lio P, et al. Global gene expression profiling and senescence biomarker analysis of hESC exposed to H2O2 induced non-cytotoxic oxidative stress. Stem Cell Res Ther. 2017;8:160 pubmed publisher
Otsubo Y, Nakashima A, Yamamoto M, Yamashita A. TORC1-Dependent Phosphorylation Targets in Fission Yeast. Biomolecules. 2017;7: pubmed publisher
Rathjen T, Yan X, Kononenko N, Ku M, Song K, Ferrarese L, et al. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nat Neurosci. 2017;20:1096-1103 pubmed publisher
Yu Z, Ruter D, Kushner E, Bautch V. Excess centrosomes induce p53-dependent senescence without DNA damage in endothelial cells. FASEB J. 2017;31:4295-4304 pubmed publisher
Potter C, Zhu W, Razafsky D, Ruzycki P, Kolesnikov A, Doggett T, et al. Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets. Curr Biol. 2017;27:2014-2022.e6 pubmed publisher
Meissner M, Mendonça L, Zhang W, Mansky L. Polymorphic Nature of Human T-Cell Leukemia Virus Type 1 Particle Cores as Revealed through Characterization of a Chronically Infected Cell Line. J Virol. 2017;91: pubmed publisher
Saito M, Otsu W, Hsu K, Chuang J, Yanagisawa T, Shieh V, et al. Tctex-1 controls ciliary resorption by regulating branched actin polymerization and endocytosis. EMBO Rep. 2017;18:1460-1472 pubmed publisher
Chen D, Ito S, Hyodo T, Asano Inami E, Yuan H, Senga T. Phosphorylation of DEPDC1 at Ser110 is required to maintain centrosome organization during mitosis. Exp Cell Res. 2017;358:101-110 pubmed publisher
Monis W, Faundez V, Pazour G. BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia. J Cell Biol. 2017;216:2131-2150 pubmed publisher
Wang C, Hong Y, Syu J, Tsai Y, Liu X, Chen T, et al. LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells. J Cell Biochem. 2018;119:314-326 pubmed publisher
Luczak M, Zhitkovich A. Nickel-induced HIF-1? promotes growth arrest and senescence in normal human cells but lacks toxic effects in transformed cells. Toxicol Appl Pharmacol. 2017;331:94-100 pubmed publisher
Tonucci F, Ferretti A, Almada E, Cribb P, Vena R, Hidalgo F, et al. Microtubules regulate brush border formation. J Cell Physiol. 2018;233:1468-1480 pubmed publisher
Lu H, Galeano M, Ott E, Kaeslin G, Kausalya P, Kramer C, et al. Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease. Nat Genet. 2017;49:1025-1034 pubmed publisher
Winkler F, Kriebel M, Clever M, Gröning S, Großhans J. Essential Function of the Serine Hydroxymethyl Transferase (SHMT) Gene During Rapid Syncytial Cell Cycles in Drosophila. G3 (Bethesda). 2017;7:2305-2314 pubmed publisher
Garg J, Feng Y, Jansen S, Friedrich J, Lezoualc h F, Schmidt M, et al. Catecholamines facilitate VEGF-dependent angiogenesis via β2-adrenoceptor-induced Epac1 and PKA activation. Oncotarget. 2017;8:44732-44748 pubmed publisher
Decker T, Kluge M, Krebs S, Shah N, Blum H, Friedel C, et al. Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1. Sci Rep. 2017;7:1684 pubmed publisher
Tomankova S, Abaffy P, Sindelka R. The role of nitric oxide during embryonic epidermis development of Xenopus laevis. Biol Open. 2017;6:862-871 pubmed publisher
Iaconis D, Monti M, Renda M, van Koppen A, Tammaro R, Chiaravalli M, et al. The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets. Sci Rep. 2017;7:1224 pubmed publisher
Martin J, Mendonça L, Angert I, MUELLER J, Zhang W, Mansky L. Disparate Contributions of Human Retrovirus Capsid Subdomains to Gag-Gag Oligomerization, Virus Morphology, and Particle Biogenesis. J Virol. 2017;91: pubmed publisher
Freitas Andrade M, Bechberger J, MacVicar B, Viau V, Naus C. Pannexin1 knockout and blockade reduces ischemic stroke injury in female, but not in male mice. Oncotarget. 2017;8:36973-36983 pubmed publisher
Ibarra M, Borini Etichetti C, Di Benedetto C, Rosano G, Margarit E, Del Sal G, et al. Dynamic regulation of Pin1 expression and function during zebrafish development. PLoS ONE. 2017;12:e0175939 pubmed publisher
Woo T, Yoon M, Hong S, Choi J, Ha N, Sun H, et al. Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest. Oncotarget. 2017;8:23690-23701 pubmed publisher
Morra F, Merolla F, Napolitano V, Ilardi G, Miro C, Paladino S, et al. The combined effect of USP7 inhibitors and PARP inhibitors in hormone-sensitive and castration-resistant prostate cancer cells. Oncotarget. 2017;8:31815-31829 pubmed publisher
Germano G, Morello G, Aveic S, Pinazza M, Minuzzo S, Frasson C, et al. ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia. Oncotarget. 2017;8:26129-26141 pubmed publisher
Huhn S, Liu J, Ye C, Lu H, Jiang X, Feng X, et al. Regulation of spindle integrity and mitotic fidelity by BCCIP. Oncogene. 2017;36:4750-4766 pubmed publisher
Chen C, Gu P, Wu J, Chen X, Niu S, Sun H, et al. Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer. Nat Commun. 2017;8:14929 pubmed publisher
Semenova I, Gupta D, Usui T, Hayakawa I, Cowan A, Rodionov V. Stimulation of microtubule-based transport by nucleation of microtubules on pigment granules. Mol Biol Cell. 2017;28:1418-1425 pubmed publisher
Canterini S, Dragotto J, Dardis A, Zampieri S, De Stefano M, Mangia F, et al. Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease. Hum Mol Genet. 2017;26:2277-2289 pubmed publisher
Nguyen A, Marin D, Zhou A, Gentilello A, Smoak E, Cao Z, et al. Identification and characterization of Aurora kinase B and C variants associated with maternal aneuploidy. Mol Hum Reprod. 2017;23:406-416 pubmed publisher
Fukuhara M, Ma Y, Nagasawa K, Toyoshima F. A G-quadruplex structure at the 5' end of the H19 coding region regulates H19 transcription. Sci Rep. 2017;8:45815 pubmed publisher
Li X, Song N, Liu L, Liu X, Ding X, Song X, et al. USP9X regulates centrosome duplication and promotes breast carcinogenesis. Nat Commun. 2017;8:14866 pubmed publisher
Santos T, Wierda K, Broeke J, Toonen R, Verhage M. Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25. J Neurosci. 2017;37:4525-4539 pubmed publisher
Bhattacharya S, Srinivasan K, Abdisalaam S, Su F, Raj P, Dozmorov I, et al. RAD51 interconnects between DNA replication, DNA repair and immunity. Nucleic Acids Res. 2017;45:4590-4605 pubmed publisher
Syu J, Baba T, Huang J, Ogawa H, Hsieh C, Hu J, et al. Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth. Sci Rep. 2017;7:240 pubmed publisher
Fishman E, Jo K, Ha A, Royfman R, Zinn A, KRISHNAMURTHY M, et al. Atypical centrioles are present in Tribolium sperm. Open Biol. 2017;7: pubmed publisher
Jansova D, Koncicka M, Tetkova A, Cerna R, Malik R, Del Llano E, et al. Regulation of 4E-BP1 activity in the mammalian oocyte. Cell Cycle. 2017;16:927-939 pubmed publisher
Sgourdou P, Mishra Gorur K, Saotome I, Henagariu O, Tuysuz B, Campos C, et al. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep. 2017;7:43708 pubmed publisher
Nagano T, Nakashima A, Onishi K, Kawai K, Awai Y, Kinugasa M, et al. Proline dehydrogenase promotes senescence through the generation of reactive oxygen species. J Cell Sci. 2017;130:1413-1420 pubmed publisher
Alfaro Aco R, Thawani A, Petry S. Structural analysis of the role of TPX2 in branching microtubule nucleation. J Cell Biol. 2017;216:983-997 pubmed publisher
Yeyati P, Schiller R, Mali G, Kasioulis I, Kawamura A, Adams I, et al. KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability. J Cell Biol. 2017;216:999-1013 pubmed publisher
Conkar D, Culfa E, Odabasi E, Rauniyar N, Yates J, Firat Karalar E. The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking. J Cell Sci. 2017;130:1450-1462 pubmed publisher
Falk S, Bugeon S, Ninkovic J, Pilz G, Postiglione M, Cremer H, et al. Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding. Neuron. 2017;93:777-791.e3 pubmed publisher
Zhang K, Lu Y, Jiang C, Liu W, Shu J, Chen X, et al. HDAC8 functions in spindle assembly during mouse oocyte meiosis. Oncotarget. 2017;8:20092-20102 pubmed publisher
Stephen J, Vilboux T, Mian L, Kuptanon C, Sinclair C, Yildirimli D, et al. Mutations in KIAA0753 cause Joubert syndrome associated with growth hormone deficiency. Hum Genet. 2017;136:399-408 pubmed publisher
Rai R, Hu C, Broton C, Chen Y, Lei M, Chang S. NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres. Mol Cell. 2017;65:801-817.e4 pubmed publisher
Hayes H, Peterson B, Haldeman J, Newgard C, Hohmeier H, Stephens S. Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival. PLoS ONE. 2017;12:e0172567 pubmed publisher
Delaney J, Patel C, Willis K, Haghighiabyaneh M, Axelrod J, Tancioni I, et al. Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. 2017;8:14423 pubmed publisher
Barber C, Netherton C, Goatley L, Moon A, Goodbourn S, Dixon L. Identification of residues within the African swine fever virus DP71L protein required for dephosphorylation of translation initiation factor eIF2α and inhibiting activation of pro-apoptotic CHOP. Virology. 2017;504:107-113 pubmed publisher
Collins C, Ellis J, Holaska J. MAPK signaling pathways and HDAC3 activity are disrupted during differentiation of emerin-null myogenic progenitor cells. Dis Model Mech. 2017;10:385-397 pubmed publisher
Shumilov A, Tsai M, Schlosser Y, Kratz A, Bernhardt K, Fink S, et al. Epstein-Barr virus particles induce centrosome amplification and chromosomal instability. Nat Commun. 2017;8:14257 pubmed publisher
Katoh Y, Michisaka S, Nozaki S, Funabashi T, Hirano T, Takei R, et al. Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system. Mol Biol Cell. 2017;28:898-906 pubmed publisher
Ramdzan Z, Ginjala V, Pinder J, Chung D, Donovan C, Kaur S, et al. The DNA repair function of CUX1 contributes to radioresistance. Oncotarget. 2017;8:19021-19038 pubmed publisher
Xiang J, Yang S, Xin N, Gaertig M, Reeves R, Li S, et al. DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome. Proc Natl Acad Sci U S A. 2017;114:E1224-E1233 pubmed publisher
Dráberová E, Sulimenko V, Vinopal S, Sulimenko T, Sladkova V, D Agostino L, et al. Differential expression of human ?-tubulin isotypes during neuronal development and oxidative stress points to a ?-tubulin-2 prosurvival function. FASEB J. 2017;31:1828-1846 pubmed publisher
Malecki J, Aileni V, Ho A, Schwarz J, Moen A, Sørensen V, et al. The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Res. 2017;45:4370-4389 pubmed publisher
Flanagan A, Stavenschi E, Basavaraju S, Gaboriau D, Hoey D, Morrison C. Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification. Mol Biol Cell. 2017;28:736-745 pubmed publisher
Gazea M, Tasouri E, Heigl T, Bosch V, Tucker K, Blaess S. Definition of a critical spatiotemporal window within which primary cilia control midbrain dopaminergic neurogenesis. Neurogenesis (Austin). 2016;3:e1248206 pubmed publisher
Phua S, Chiba S, Suzuki M, Su E, Roberson E, Pusapati G, et al. Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017;168:264-279.e15 pubmed publisher
Upadhyay M, Agarwal S, Bhadauriya P, Ganesh S. Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models. Neurobiol Dis. 2017;100:39-51 pubmed publisher
Chen M, Wang J, Jiang J, Zheng X, Justice N, Wang K, et al. APP modulates KCC2 expression and function in hippocampal GABAergic inhibition. elife. 2017;6: pubmed publisher
Hube F, Ulveling D, Sureau A, Forveille S, Francastel C. Short intron-derived ncRNAs. Nucleic Acids Res. 2017;45:4768-4781 pubmed publisher
Gloerich M, Bianchini J, Siemers K, Cohen D, Nelson W. Cell division orientation is coupled to cell-cell adhesion by the E-cadherin/LGN complex. Nat Commun. 2017;8:13996 pubmed publisher
Jao L, Akef A, Wente S. A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. Mol Biol Cell. 2017;28:120-127 pubmed publisher
Hauge S, Naucke C, Hasvold G, Joel M, Rødland G, Juzenas P, et al. Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading. Oncotarget. 2017;8:10966-10979 pubmed publisher
Sha L, Wang X, Li J, Shi X, Wu L, Shen Y, et al. Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy. J Exp Med. 2017;214:547-563 pubmed publisher
Lee K, Yim H, Shin J, Lee C, Lee J, Jeong J. FGF11 induced by hypoxia interacts with HIF-1? and enhances its stability. FEBS Lett. 2017;591:348-357 pubmed publisher
Sukumaran S, Stumpf M, Salamon S, Ahmad I, Bhattacharya K, Fischer S, et al. CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly. Mol Genet Genomics. 2017;292:365-383 pubmed publisher
Ho S, Rao R, To S, Schoch E, Tarapore P. Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer. Endocr Relat Cancer. 2017;24:83-96 pubmed publisher
Foerster P, Daclin M, Asm S, Faucourt M, Boletta A, Genovesio A, et al. mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis. Development. 2017;144:201-210 pubmed publisher
Zhang T, Zhou Y, Li L, Wang Z, Shen W, Schatten H, et al. CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes. Development. 2017;144:305-312 pubmed publisher
Yi Z, Ma X, Liang Q, Zhang T, Xu Z, Meng T, et al. Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes. Sci Rep. 2016;6:38574 pubmed publisher
Fu Q, Hu Y, Wang Q, Liu Y, Li N, Xu B, et al. High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts. J Physiol. 2017;595:1973-1986 pubmed publisher
Fedosyuk S, Bezerra G, Radakovics K, Smith T, Sammito M, Bobik N, et al. Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins. PLoS Pathog. 2016;12:e1006079 pubmed publisher
Baek I, Jang Y, Lee T, Lee J. Kinetic analysis of de novo centriole assembly in heat-shocked mammalian cells. Cytoskeleton (Hoboken). 2017;74:18-28 pubmed publisher
Patel S, Randle S, Gibbs S, Cooke A, Laman H. Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27. Cell Mol Life Sci. 2017;74:1553-1566 pubmed publisher
Singh R, Dagnino L. CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes. Oncotarget. 2017;8:4977-4993 pubmed publisher
Watanabe Y, Honda S, Konishi A, Arakawa S, Murohashi M, Yamaguchi H, et al. Autophagy controls centrosome number by degrading Cep63. Nat Commun. 2016;7:13508 pubmed publisher
Tarrant D, Stirpe M, Rowe M, Howard M, von der Haar T, Gourlay C. Inappropriate expression of the translation elongation factor 1A disrupts genome stability and metabolism. J Cell Sci. 2016;129:4455-4465 pubmed
Doksani Y, de Lange T. Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining. Cell Rep. 2016;17:1646-1656 pubmed publisher
Jin H, Komita M, Koseki H, Aoe T. Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1. Cell Stress Chaperones. 2017;22:77-85 pubmed publisher
Zimmermann M, Arachchige Don A, Donaldson M, Patriarchi T, Horne M. Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival. Cell Cycle. 2016;15:3278-3295 pubmed
Resende L, Amaral C, Soares R, Alves A, Alves Dos Santos L, Britto L, et al. Social stress in adolescents induces depression and brain-region-specific modulation of the transcription factor MAX. Transl Psychiatry. 2016;6:e914 pubmed publisher
Xing M, Peterman M, Davis R, Oegema K, Shiau A, Field S. GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge. Mol Biol Cell. 2016;27:3828-3840 pubmed
Rosselló C, Lindström L, Glindre J, Eklund G, Alvarado Kristensson M. Gamma-tubulin coordinates nuclear envelope assembly around chromatin. Heliyon. 2016;2:e00166 pubmed
Kishikawa T, Otsuka M, Yoshikawa T, Ohno M, Ijichi H, Koike K. Satellite RNAs promote pancreatic oncogenic processes via the dysfunction of YBX1. Nat Commun. 2016;7:13006 pubmed publisher
Mobin M, Gerstberger S, Teupser D, Campana B, Charisse K, Heim M, et al. The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation. Nat Commun. 2016;7:12848 pubmed publisher
Hoang Minh L, Deleyrolle L, Nakamura N, Parker A, Martuscello R, Reynolds B, et al. PCM1 Depletion Inhibits Glioblastoma Cell Ciliogenesis and Increases Cell Death and Sensitivity to Temozolomide. Transl Oncol. 2016;9:392-402 pubmed publisher
Sukhotnik I, Nissimov N, Ben Shahar Y, Moati D, Bitterman N, Pollak Y, et al. Fenofibrate reduces intestinal damage and improves intestinal recovery following intestinal ischemia-reperfusion injury in a rat. Pediatr Surg Int. 2016;32:1193-1200 pubmed
Ortega Atienza S, Rubis B, McCarthy C, Zhitkovich A. Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins. Am J Pathol. 2016;186:2857-2868 pubmed publisher
Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, et al. Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling. Development. 2016;143:3944-3955 pubmed
Lescale C, Lenden Hasse H, Blackford A, Balmus G, Bianchi J, Yu W, et al. Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination. Cell Rep. 2016;16:2967-2979 pubmed publisher
Jonsson M, Ragnum H, Julin C, Yeramian A, Clancy T, Frikstad K, et al. Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition. Br J Cancer. 2016;115:929-939 pubmed publisher
Kaur S, Coulombe Y, Ramdzan Z, Leduy L, Masson J, Nepveu A. Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair. J Biol Chem. 2016;291:22769-22780 pubmed
Balboula A, Nguyen A, Gentilello A, Quartuccio S, Drutovic D, Solc P, et al. Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes. J Cell Sci. 2016;129:3648-3660 pubmed
Huo Q, Chen M, He Q, Zhang J, Li B, Jin K, et al. Prefrontal Cortical GABAergic Dysfunction Contributes to Aberrant UP-State Duration in APP Knockout Mice. Cereb Cortex. 2017;27:4060-4072 pubmed publisher
Dubnikov T, Ben Gedalya T, Reiner R, Hoepfner D, Cabral W, Marini J, et al. PrP-containing aggresomes are cytosolic components of an ER quality control mechanism. J Cell Sci. 2016;129:3635-3647 pubmed
Nagano T, Nakano M, Nakashima A, Onishi K, Yamao S, Enari M, et al. Identification of cellular senescence-specific genes by comparative transcriptomics. Sci Rep. 2016;6:31758 pubmed publisher
Kratter I, Zahed H, Lau A, Tsvetkov A, Daub A, Weiberth K, et al. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. J Clin Invest. 2016;126:3585-97 pubmed publisher
Gao M, Monian P, Pan Q, Zhang W, Xiang J, Jiang X. Ferroptosis is an autophagic cell death process. Cell Res. 2016;26:1021-32 pubmed publisher
Dutta N, Seo S. RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner. Biol Open. 2016;5:1283-9 pubmed publisher
Bernabé Rubio M, Andrés G, Casares Arias J, Fernández Barrera J, Rangel L, Reglero Real N, et al. Novel role for the midbody in primary ciliogenesis by polarized epithelial cells. J Cell Biol. 2016;214:259-73 pubmed publisher
Gottimukkala K, Jangid R, Patta I, Sultana D, Sharma A, Misra Sen J, et al. Regulation of SATB1 during thymocyte development by TCR signaling. Mol Immunol. 2016;77:34-43 pubmed publisher
Sánchez Huertas C, Freixo F, Viais R, Lacasa C, Soriano E, Lüders J. Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity. Nat Commun. 2016;7:12187 pubmed publisher
Rogers E, Spracklen A, Bilancia C, Sumigray K, Allred S, Nowotarski S, et al. Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis. Mol Biol Cell. 2016;27:2613-31 pubmed publisher
Bond S, Abramyan J, Fu K, Naus C, Richman J. Pannexin 3 is required for late stage bone growth but not for initiation of ossification in avian embryos. Dev Dyn. 2016;245:913-24 pubmed publisher
Daniele L, Emran F, Lobo G, Gaivin R, Perkins B. Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function. Invest Ophthalmol Vis Sci. 2016;57:2942-54 pubmed publisher
Hintermair C, Voß K, Forné I, Heidemann M, Flatley A, Kremmer E, et al. Specific threonine-4 phosphorylation and function of RNA polymerase II CTD during M phase progression. Sci Rep. 2016;6:27401 pubmed publisher
van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed publisher
Kalchschmidt J, Bashford Rogers R, Paschos K, Gillman A, Styles C, Kellam P, et al. Epstein-Barr virus nuclear protein EBNA3C directly induces expression of AID and somatic mutations in B cells. J Exp Med. 2016;213:921-8 pubmed publisher
Varadarajan R, Ayeni J, Jin Z, Homola E, Campbell S. Myt1 inhibition of Cyclin A/Cdk1 is essential for fusome integrity and premeiotic centriole engagement in Drosophila spermatocytes. Mol Biol Cell. 2016;27:2051-63 pubmed publisher
Menietti E, Xu X, Ostano P, Joseph J, Lefort K, Dotto G. Negative control of CSL gene transcription by stress/DNA damage response and p53. Cell Cycle. 2016;15:1767-78 pubmed publisher
Cho J, Chun H, Lee J, Lee J, Cheong K, Jung Y, et al. Prevention effect of rare ginsenosides against stress-hormone induced MTOC amplification. Oncotarget. 2016;7:35144-58 pubmed publisher
Perez M, Lucena Cacace A, Marín Gómez L, Padillo Ruiz J, Robles Frias M, Saez C, et al. Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src. Oncotarget. 2016;7:33111-24 pubmed publisher
Tang A, Shi P, Song A, Zou D, Zhou Y, Gu P, et al. PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte. Cell Cycle. 2016;15:1450-61 pubmed publisher
Cortés C, McInerney Leo A, Vogel I, Rondón Galeano M, Leo P, Harris J, et al. Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function. Sci Rep. 2016;6:24083 pubmed publisher
Chu C, Ossipova O, Ioannou A, Sokol S. Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth. Sci Rep. 2016;6:24104 pubmed publisher
Reid E, Juleff N, Windsor M, Gubbins S, Roberts L, Morgan S, et al. Type I and III IFNs Produced by Plasmacytoid Dendritic Cells in Response to a Member of the Flaviviridae Suppress Cellular Immune Responses. J Immunol. 2016;196:4214-26 pubmed publisher
Singh R, Dagnino L. E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair. Oncotarget. 2016;7:26275-92 pubmed publisher
Li L, Grausam K, Wang J, Lun M, Ohli J, Lidov H, et al. Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells. Nat Cell Biol. 2016;18:418-30 pubmed publisher
Kuschal C, Botta E, Orioli D, DiGiovanna J, Seneca S, Keymolen K, et al. GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy. Am J Hum Genet. 2016;98:627-42 pubmed publisher
Yadav S, Sharma N, Liu C, Dong L, Li T, Swaroop A. Centrosomal protein CP110 controls maturation of the mother centriole during cilia biogenesis. Development. 2016;143:1491-501 pubmed publisher
Gibbs B, Damerla R, Vladar E, Chatterjee B, Wan Y, Liu X, et al. Prickle1 mutation causes planar cell polarity and directional cell migration defects associated with cardiac outflow tract anomalies and other structural birth defects. Biol Open. 2016;5:323-35 pubmed publisher
Bianchi E, Boekelheide K, Sigman M, Lamb D, Hall S, Hwang K. Ghrelin ameliorates adhesions in a postsurgical mouse model. J Surg Res. 2016;201:226-34 pubmed publisher
Grego Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson K. The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. elife. 2016;5:e12034 pubmed publisher
Schüller R, Forné I, Straub T, Schreieck A, Texier Y, Shah N, et al. Heptad-Specific Phosphorylation of RNA Polymerase II CTD. Mol Cell. 2016;61:305-14 pubmed publisher
Naylor R, Jeganathan K, Cao X, van Deursen J. Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy. J Clin Invest. 2016;126:543-59 pubmed publisher
Chen T, Syu J, Lin T, Cheng H, Lu F, Wang C. Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells. Oncogenesis. 2015;4:e180 pubmed publisher
Kurtulmus B, Wang W, Ruppert T, Neuner A, Cerikan B, Viol L, et al. WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis. J Cell Sci. 2016;129:621-36 pubmed publisher
Fujimoto I, Hasegawa K, Fujiwara K, Yamada M, Yoshikawa K. Necdin controls EGFR signaling linked to astrocyte differentiation in primary cortical progenitor cells. Cell Signal. 2016;28:94-107 pubmed publisher
Du J, Cao Y, Wang Q, Zhang N, Liu X, Chen D, et al. Unique subcellular distribution of phosphorylated Plk1 (Ser137 and Thr210) in mouse oocytes during meiotic division and pPlk1(Ser137) involvement in spindle formation and REC8 cleavage. Cell Cycle. 2015;14:3566-79 pubmed publisher
Valdano M, Cavatorta A, Morale M, Marziali F, de Souza Lino V, Steenbergen R, et al. Disc large 1 expression is altered by human papillomavirus E6/E7 proteins in organotypic cultures of human keratinocytes. J Gen Virol. 2016;97:453-62 pubmed publisher
Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, et al. The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells. J Cell Biol. 2015;211:963-73 pubmed publisher
Ge Y, Onengut Gumuscu S, Quinlan A, Mackey A, Wright J, Buckner J, et al. Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes. Diabetes. 2016;65:794-802 pubmed publisher
Beaton N, Rudigier C, Moest H, Müller S, Mrosek N, Röder E, et al. TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling. Mol Metab. 2015;4:795-810 pubmed publisher
Fu J, Lipinszki Z, Rangone H, Min M, Mykura C, Chao Chu J, et al. Conserved molecular interactions in centriole-to-centrosome conversion. Nat Cell Biol. 2016;18:87-99 pubmed publisher
Xu Z, Ma X, Qi S, Wang Z, Guo L, Schatten H, et al. Cep55 regulates spindle organization and cell cycle progression in meiotic oocyte. Sci Rep. 2015;5:16978 pubmed publisher
Voss K, Forne I, Descostes N, Hintermair C, Schüller R, Maqbool M, et al. Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II. Transcription. 2015;6:91-101 pubmed publisher
Hori A, Morand A, Ikebe C, Frith D, Snijders A, Toda T. The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation. Biochem Biophys Res Commun. 2015;468:39-45 pubmed publisher
Silva E, Betleja E, John E, Spear P, Moresco J, Zhang S, et al. Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry. Mol Biol Cell. 2016;27:48-63 pubmed publisher
Endicott S, Basu B, Khokha M, Brueckner M. The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry. Development. 2015;142:4068-79 pubmed publisher
Lingel A, Ehlers E, Wang Q, Cao M, Wood C, Lin R, et al. Kaposi's Sarcoma-Associated Herpesvirus Reduces Cellular Myeloid Differentiation Primary-Response Gene 88 (MyD88) Expression via Modulation of Its RNA. J Virol. 2016;90:180-8 pubmed publisher
Lokaj M, Kösling S, Koerner C, Lange S, van Beersum S, van Reeuwijk J, et al. The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function. Structure. 2015;23:2122-32 pubmed publisher
Vidak S, Kubben N, Dechat T, Foisner R. Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins. Genes Dev. 2015;29:2022-36 pubmed publisher
Ben Gedalya T, Moll L, Bejerano Sagie M, Frere S, Cabral W, Friedmann Morvinski D, et al. Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction. EMBO J. 2015;34:2820-39 pubmed publisher
Shnitsar I, Bashkurov M, Masson G, Ogunjimi A, Mosessian S, Cabeza E, et al. PTEN regulates cilia through Dishevelled. Nat Commun. 2015;6:8388 pubmed publisher
Malicdan M, Vilboux T, Stephen J, Maglic D, Mian L, Konzman D, et al. Mutations in human homologue of chicken talpid3 gene (KIAA0586) cause a hybrid ciliopathy with overlapping features of Jeune and Joubert syndromes. J Med Genet. 2015;52:830-9 pubmed publisher
Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J. 2015;34:2885-902 pubmed publisher
Dorfman T, Pollak Y, Sohotnik R, Coran A, Bejar J, Sukhotnik I. Enhanced intestinal epithelial cell proliferation in diabetic rats correlates with β-catenin accumulation. J Endocrinol. 2015;226:135-43 pubmed publisher
Martino J, Holmes A, Xie H, Wise S, Wise J. Chronic Exposure to Particulate Chromate Induces Premature Centrosome Separation and Centriole Disengagement in Human Lung Cells. Toxicol Sci. 2015;147:490-9 pubmed publisher
Shukla A, Kong D, Sharma M, Magidson V, Loncarek J. Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation. Nat Commun. 2015;6:8077 pubmed publisher
Håland T, Boye E, Stokke T, Grallert B, Syljuåsen R. Simultaneous measurement of passage through the restriction point and MCM loading in single cells. Nucleic Acids Res. 2015;43:e150 pubmed publisher
Borek W, Groocock L, Samejima I, Zou J, de Lima Alves F, Rappsilber J, et al. Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis. Nat Commun. 2015;6:7929 pubmed publisher
Falcón Urrutia P, Carrasco C, Lois P, Palma V, Roth A. Shh Signaling through the Primary Cilium Modulates Rat Oligodendrocyte Differentiation. PLoS ONE. 2015;10:e0133567 pubmed publisher
Pozsgai E, Griffin D, Heller K, Mendell J, Rodino Klapac L. β-Sarcoglycan gene transfer decreases fibrosis and restores force in LGMD2E mice. Gene Ther. 2016;23:57-66 pubmed publisher
Yan K, Li L, Wang X, Hong R, Zhang Y, Yang H, et al. The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells. J Cell Biol. 2015;210:209-24 pubmed publisher
Fiering S, Ang L, Lacoste J, Smith T, Griner E. Registered report: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis. elife. 2015;4:e04796 pubmed publisher
Zengin T, Ekinci B, Kucukkose C, Yalcin Ozuysal O. IRF6 Is Involved in the Regulation of Cell Proliferation and Transformation in MCF10A Cells Downstream of Notch Signaling. PLoS ONE. 2015;10:e0132757 pubmed publisher
Gerhardt C, Lier J, Burmühl S, Struchtrup A, Deutschmann K, Vetter M, et al. The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium. J Cell Biol. 2015;210:115-33 pubmed publisher
Chou C, Loh J, Yang M, Lin C, Hong M, Cho C, et al. AIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1. Cell Cycle. 2015;14:2764-76 pubmed publisher
Dráberová E, D Agostino L, Caracciolo V, Sládková V, Sulimenko T, Sulimenko V, et al. Overexpression and Nucleolar Localization of γ-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma. J Neuropathol Exp Neurol. 2015;74:723-42 pubmed publisher
Bédard N, Jammoul S, Moore T, Wykes L, Hallauer P, Hastings K, et al. Inactivation of the ubiquitin-specific protease 19 deubiquitinating enzyme protects against muscle wasting. FASEB J. 2015;29:3889-98 pubmed publisher
Mones S, Gess B, Bordignon B, Altié A, Young P, Bihel F, et al. CMTX1 patients' cells present genomic instability corrected by CamKII inhibitors. Orphanet J Rare Dis. 2015;10:56 pubmed publisher
Kalfalah F, Berg E, Christensen M, Linka R, Dirks W, Boege F, et al. Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis. Cell Cycle. 2015;14:1704-15 pubmed publisher
Zhang B, Zhang T, Wang G, Wang G, Chi W, Jiang Q, et al. GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis. PLoS Biol. 2015;13:e1002129 pubmed publisher
Breslow D, Nachury M. Analysis of soluble protein entry into primary cilia using semipermeabilized cells. Methods Cell Biol. 2015;127:203-21 pubmed publisher
Blouw B, Patel M, Iizuka S, Abdullah C, You W, Huang X, et al. The invadopodia scaffold protein Tks5 is required for the growth of human breast cancer cells in vitro and in vivo. PLoS ONE. 2015;10:e0121003 pubmed publisher
Ji Z, McHale C, Bersonda J, Tung J, Smith M, Zhang L. Induction of centrosome amplification by formaldehyde, but not hydroquinone, in human lymphoblastoid TK6 cells. Environ Mol Mutagen. 2015;56:535-44 pubmed publisher
Carelli V, Musumeci O, Caporali L, Zanna C, La Morgia C, Del Dotto V, et al. Syndromic parkinsonism and dementia associated with OPA1 missense mutations. Ann Neurol. 2015;78:21-38 pubmed publisher
Ortega Atienza S, Green S, Zhitkovich A. Proteasome activity is important for replication recovery, CHK1 phosphorylation and prevention of G2 arrest after low-dose formaldehyde. Toxicol Appl Pharmacol. 2015;286:135-41 pubmed publisher
Kobayashi A, Hashizume C, Dowaki T, Wong R. Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A. Cell Cycle. 2015;14:1447-58 pubmed publisher
Kuwabara W, Zhang L, Schuiki I, Curi R, Volchuk A, Alba Loureiro T. NADPH oxidase-dependent production of reactive oxygen species induces endoplasmatic reticulum stress in neutrophil-like HL60 cells. PLoS ONE. 2015;10:e0116410 pubmed publisher
Lázaro Diéguez F, Ispolatov I, Müsch A. Cell shape impacts on the positioning of the mitotic spindle with respect to the substratum. Mol Biol Cell. 2015;26:1286-95 pubmed publisher
Chong Y, Mann R, Zhao C, Kato M, Beachy P. Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5. Genes Dev. 2015;29:262-76 pubmed publisher
Mateos Gomez P, Gong F, Nair N, Miller K, Lazzerini Denchi E, Sfeir A. Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination. Nature. 2015;518:254-7 pubmed publisher
Marsolier J, Perichon M, Debarry J, Villoutreix B, Chluba J, Lopez T, et al. Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation. Nature. 2015;520:378-82 pubmed publisher
Bangs F, Schrode N, Hadjantonakis A, Anderson K. Lineage specificity of primary cilia in the mouse embryo. Nat Cell Biol. 2015;17:113-22 pubmed publisher
Tamura N, Simon J, Nayak A, Shenoy R, Hiroi N, Boilot V, et al. A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset. Biol Open. 2015;4:155-69 pubmed publisher
Lee I, Lee C, Lee J. CaMKKβ-AMPKα2 signaling contributes to mitotic Golgi fragmentation and the G2/M transition in mammalian cells. Cell Cycle. 2015;14:598-611 pubmed publisher
Gaume X, Tassin A, Ugrinova I, Mongelard F, Monier K, Bouvet P. Centrosomal nucleolin is required for microtubule network organization. Cell Cycle. 2015;14:902-19 pubmed publisher
Zhao H, Faltermeier C, Mendelsohn L, Porter P, Clurman B, Roberts J. Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy. Oncotarget. 2014;5:12704-14 pubmed
Waters A, Asfahani R, Carroll P, Bicknell L, Lescai F, Bright A, et al. The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes. J Med Genet. 2015;52:147-56 pubmed publisher
Torkko J, Primo M, Dirkx R, Friedrich A, Viehrig A, Vergari E, et al. Stability of proICA512/IA-2 and its targeting to insulin secretory granules require β4-sheet-mediated dimerization of its ectodomain in the endoplasmic reticulum. Mol Cell Biol. 2015;35:914-27 pubmed publisher
Lee Y, Park I, Lee H. Partial Hepatectomy in Acetylation-Deficient BubR1 Mice Corroborates that Chromosome Missegregation Initiates Tumorigenesis. Endocrinol Metab (Seoul). 2014;29:561-6 pubmed publisher
Narasimhan V, Hjeij R, Vij S, Loges N, Wallmeier J, Koerner Rettberg C, et al. Mutations in CCDC11, which encodes a coiled-coil containing ciliary protein, causes situs inversus due to dysmotility of monocilia in the left-right organizer. Hum Mutat. 2015;36:307-18 pubmed publisher
Jung Y, Chun H, Yoon M, Park B. Elevated estrogen receptor-α in VHL-deficient condition induces microtubule organizing center amplification via disruption of BRCA1/Rad51 interaction. Neoplasia. 2014;16:1070-81 pubmed publisher
Volovik Y, Moll L, Marques F, Maman M, Bejerano Sagie M, Cohen E. Differential regulation of the heat shock factor 1 and DAF-16 by neuronal nhl-1 in the nematode C. elegans. Cell Rep. 2014;9:2192-205 pubmed publisher
Ouaret D, Larsen A. Protein kinase C β inhibition by enzastaurin leads to mitotic missegregation and preferential cytotoxicity toward colorectal cancer cells with chromosomal instability (CIN). Cell Cycle. 2014;13:2697-706 pubmed publisher
Jilani Y, Lu S, Lei H, Karnitz L, Chadli A. UNC45A localizes to centrosomes and regulates cancer cell proliferation through ChK1 activation. Cancer Lett. 2015;357:114-20 pubmed publisher
Pathania S, Bade S, Le Guillou M, Burke K, Reed R, Bowman Colin C, et al. BRCA1 haploinsufficiency for replication stress suppression in primary cells. Nat Commun. 2014;5:5496 pubmed publisher
Eblimit A, Nguyen T, Chen Y, Esteve Rudd J, Zhong H, Letteboer S, et al. Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina. Hum Mol Genet. 2015;24:1584-601 pubmed publisher
Cao M, Wang Q, Lingel A, Zhang L. Nuclear factor κB represses the expression of latent membrane protein 1 in Epstein-Barr virus transformed cells. World J Virol. 2014;3:22-9 pubmed publisher
Reed S, Hagen J, Muniz V, Rosean T, Borcherding N, Sciegienka S, et al. NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas. PLoS ONE. 2014;9:e112126 pubmed publisher
Gerdes J, Christou Savina S, Xiong Y, Moede T, Moruzzi N, Karlsson Edlund P, et al. Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents. Nat Commun. 2014;5:5308 pubmed publisher
Wang H, Zou X, Wei Z, Wu Y, Li R, Zeng R, et al. Hsp90α forms a stable complex at the cilium neck for the interaction of signalling molecules in IGF-1 receptor signalling. J Cell Sci. 2015;128:100-8 pubmed publisher
Taschner M, Kotsis F, Braeuer P, Kuehn E, Lorentzen E. Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly. J Cell Biol. 2014;207:269-82 pubmed publisher
Le Pabic P, Ng C, Schilling T. Fat-Dachsous signaling coordinates cartilage differentiation and polarity during craniofacial development. PLoS Genet. 2014;10:e1004726 pubmed publisher
Paulus J, Link B. Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics. PLoS ONE. 2014;9:e109922 pubmed publisher
Chu Y, Gómez Rosso L, Huang P, Wang Z, Xu Y, Yao X, et al. Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity. Cell Res. 2014;24:1250-65 pubmed publisher
Meinke P, Mattioli E, Haque F, Antoku S, Columbaro M, Straatman K, et al. Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization. PLoS Genet. 2014;10:e1004605 pubmed publisher
Asante D, Stevenson N, Stephens D. Subunit composition of the human cytoplasmic dynein-2 complex. J Cell Sci. 2014;127:4774-87 pubmed publisher
Jin D, Ni T, Sun J, Wan H, Amack J, Yu G, et al. Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. Nat Cell Biol. 2014;16:841-51 pubmed publisher
Wang J, Zhu H, Chu M, Liu Y, Zhang C, Liu G, et al. Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages. Nat Commun. 2014;5:4758 pubmed publisher
Kim J, Lee J, Park M, Yoon I, Kim K, Lee M, et al. AIMP1 negatively regulates adipogenesis by inhibiting PPARγ. J Cell Sci. 2014;127:4483-93 pubmed publisher
Choksi S, Babu D, Lau D, Yu X, Roy S. Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Development. 2014;141:3410-9 pubmed publisher
Chang C, Schock E, O Hare E, Dodgson J, Cheng H, Muir W, et al. The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2. Development. 2014;141:3003-12 pubmed publisher
Chen Y, Huang A, Lin L. Sphere-forming-like cells (squamospheres) with cancer stem-like cell traits from VX2 rabbit buccal squamous cell carcinoma. Int J Oral Sci. 2014;6:212-8 pubmed publisher
Zhang L, Nosak C, Sollazzo P, Odisho T, Volchuk A. IRE1 inhibition perturbs the unfolded protein response in a pancreatic ?-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis. BMC Cell Biol. 2014;15:29 pubmed publisher
Chen L, Munoz Antonia T, Cress W. Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines. PLoS ONE. 2014;9:e101040 pubmed publisher
O Rourke B, Gomez Ferreria M, Berk R, Hackl A, Nicholas M, O Rourke S, et al. Cep192 controls the balance of centrosome and non-centrosomal microtubules during interphase. PLoS ONE. 2014;9:e101001 pubmed publisher
Machicoane M, de Frutos C, Fink J, Rocancourt M, Lombardi Y, Garel S, et al. SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation. J Cell Biol. 2014;205:791-9 pubmed publisher
Gur I, Fujiwara K, Hasegawa K, Yoshikawa K. Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase. PLoS ONE. 2014;9:e99503 pubmed publisher
Yau K, van Beuningen S, Cunha Ferreira I, Cloin B, van Battum E, Will L, et al. Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development. Neuron. 2014;82:1058-73 pubmed publisher
Ravens S, Fournier M, Ye T, Stierlé M, Dembele D, Chavant V, et al. Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation. elife. 2014;3: pubmed publisher
Osbourne A, Calway T, Broman M, McSharry S, Earley J, Kim G. Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias. J Mol Cell Cardiol. 2014;74:53-63 pubmed publisher
Shi Y, Wang J, Chandarlapaty S, Cross J, Thompson C, Rosen N, et al. PTEN is a protein tyrosine phosphatase for IRS1. Nat Struct Mol Biol. 2014;21:522-7 pubmed publisher
Hett A, West S. Inhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus. PLoS ONE. 2014;9:e96174 pubmed publisher
Zhang Y, Xiong S, Li Q, Hu S, Tashakori M, Van Pelt C, et al. Tissue-specific and age-dependent effects of global Mdm2 loss. J Pathol. 2014;233:380-91 pubmed publisher
Nam H, van Deursen J. Cyclin B2 and p53 control proper timing of centrosome separation. Nat Cell Biol. 2014;16:538-49 pubmed publisher
Heideman M, Lancini C, Proost N, Yanover E, Jacobs H, Dannenberg J. Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis. Haematologica. 2014;99:1292-303 pubmed publisher
Bazzi H, Anderson K. Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo. Proc Natl Acad Sci U S A. 2014;111:E1491-500 pubmed publisher
Hardy T, Lee M, Hames R, Prosser S, Cheary D, Samant M, et al. Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction. J Cell Sci. 2014;127:2493-506 pubmed publisher
Ruppersburg C, Hartzell H. The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis. Mol Biol Cell. 2014;25:1793-807 pubmed publisher
Bjerke G, Pietrzak K, Melhuish T, Frierson H, Paschal B, Wotton D. Prostate cancer induced by loss of Apc is restrained by TGF? signaling. PLoS ONE. 2014;9:e92800 pubmed publisher
Wallace N, Robinson K, Galloway D. Beta human papillomavirus E6 expression inhibits stabilization of p53 and increases tolerance of genomic instability. J Virol. 2014;88:6112-27 pubmed publisher
d Alcontres M, Palacios J, Mejias D, Blasco M. TopoII? prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres. Cell Cycle. 2014;13:1463-81 pubmed publisher
Ramdzan Z, Vadnais C, Pal R, Vandal G, Cadieux C, Leduy L, et al. RAS transformation requires CUX1-dependent repair of oxidative DNA damage. PLoS Biol. 2014;12:e1001807 pubmed publisher
Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, et al. Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1). PLoS ONE. 2014;9:e90687 pubmed publisher
Kasioulis I, Syred H, Tate P, Finch A, Shaw J, Seawright A, et al. Kdm3a lysine demethylase is an Hsp90 client required for cytoskeletal rearrangements during spermatogenesis. Mol Biol Cell. 2014;25:1216-33 pubmed publisher
Yokoyama H, Koch B, Walczak R, Ciray Duygu F, González Sánchez J, Devos D, et al. The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation. Nat Commun. 2014;5:3270 pubmed publisher
Jiang K, Hua S, Mohan R, Grigoriev I, Yau K, Liu Q, et al. Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition. Dev Cell. 2014;28:295-309 pubmed publisher
Ba n Rodr guez I, G lvez Santisteban M, Vergarajauregui S, Bosch M, Borreguero Pascual A, Mart n Belmonte F. EGFR controls IQGAP basolateral membrane localization and mitotic spindle orientation during epithelial morphogenesis. EMBO J. 2014;33:129-45 pubmed publisher
Tattikota S, Rathjen T, McAnulty S, Wessels H, Akerman I, van de Bunt M, et al. Argonaute2 mediates compensatory expansion of the pancreatic β cell. Cell Metab. 2014;19:122-34 pubmed publisher
Klinger M, Wang W, Kuhns S, Bärenz F, Dräger Meurer S, Pereira G, et al. The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone. Mol Biol Cell. 2014;25:495-507 pubmed publisher
Delling M, DeCaen P, Doerner J, Febvay S, Clapham D. Primary cilia are specialized calcium signalling organelles. Nature. 2013;504:311-4 pubmed publisher
Cui C, Chatterjee B, Lozito T, Zhang Z, Francis R, Yagi H, et al. Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol. 2013;11:e1001720 pubmed publisher
Subtil Rodríguez A, Vázquez Chávez E, Ceballos Chávez M, Rodríguez Paredes M, Martin Subero J, Esteller M, et al. The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes. Nucleic Acids Res. 2014;42:2185-96 pubmed publisher
Yumoto T, Nakadate K, Nakamura Y, Sugitani Y, Sugitani Yoshida R, Ueda S, et al. Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors. PLoS ONE. 2013;8:e79895 pubmed publisher
Grimaldi A, Balestrieri M, D Onofrio N, Di Domenico G, Nocera C, Lamberti M, et al. The synergistic effect of everolimus and chloroquine on endothelial cell number reduction is paralleled by increased apoptosis and reduced autophagy occurrence. PLoS ONE. 2013;8:e79658 pubmed publisher
Farag H, Froehler S, Oexle K, Ravindran E, Schindler D, Staab T, et al. Abnormal centrosome and spindle morphology in a patient with autosomal recessive primary microcephaly type 2 due to compound heterozygous WDR62 gene mutation. Orphanet J Rare Dis. 2013;8:178 pubmed publisher
Kuo D, Labelle Dumais C, Mao M, Jeanne M, Kauffman W, Allen J, et al. Allelic heterogeneity contributes to variability in ocular dysgenesis, myopathy and brain malformations caused by Col4a1 and Col4a2 mutations. Hum Mol Genet. 2014;23:1709-22 pubmed publisher
Breslow D, Koslover E, Seydel F, Spakowitz A, Nachury M. An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier. J Cell Biol. 2013;203:129-47 pubmed publisher
Matsubayashi M, Teramoto Kimata I, Uni S, Lillehoj H, Matsuda H, Furuya M, et al. Elongation factor-1? is a novel protein associated with host cell invasion and a potential protective antigen of Cryptosporidium parvum. J Biol Chem. 2013;288:34111-20 pubmed publisher
Green S, Luczak M, Morse J, Deloughery Z, Zhitkovich A. Uptake, p53 pathway activation, and cytotoxic responses for Co(II) and Ni(II) in human lung cells: implications for carcinogenicity. Toxicol Sci. 2013;136:467-77 pubmed publisher
Casadei N, Pöhler A, Tomas Zapico C, Torres Peraza J, Schwedhelm I, Witz A, et al. Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice. Hum Mol Genet. 2014;23:767-81 pubmed publisher
Horn H, Kim D, Wright G, Wong E, Stewart C, Burke B, et al. A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton. J Cell Biol. 2013;202:1023-39 pubmed publisher
Morse J, Luczak M, Zhitkovich A. Chromium(VI) causes interstrand DNA cross-linking in vitro but shows no hypersensitivity in cross-link repair-deficient human cells. Chem Res Toxicol. 2013;26:1591-8 pubmed publisher
Tamura A, Huang T, Marikawa Y. Impact of vitrification on the meiotic spindle and components of the microtubule-organizing center in mouse mature oocytes. Biol Reprod. 2013;89:112 pubmed publisher
Dhani D, Goult B, George G, Rogerson D, Bitton D, Miller C, et al. Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3(Alp6). Mol Biol Cell. 2013;24:3337-49 pubmed publisher
Bjerke G, Yang C, Frierson H, Paschal B, Wotton D. Activation of Akt signaling in prostate induces a TGF?-mediated restraint on cancer progression and metastasis. Oncogene. 2014;33:3660-7 pubmed publisher
Voss M, Campbell K, Saranzewa N, Campbell D, Hastie C, Peggie M, et al. Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with ?-tubulin. Cell Cycle. 2013;12:2876-87 pubmed publisher
Tan E, Caro S, Potnis A, Lanza C, Slawson C. O-linked N-acetylglucosamine cycling regulates mitotic spindle organization. J Biol Chem. 2013;288:27085-99 pubmed publisher
Swaid F, Sukhotnik I, Matter I, Berkowitz D, Hadjittofi C, Pollak Y, et al. Dietary glutamine supplementation prevents mucosal injury and modulates intestinal epithelial restitution following acetic acid induced intestinal injury in rats. Nutr Metab (Lond). 2013;10:53 pubmed publisher
McElwee M, Beilstein F, Labetoulle M, Rixon F, Pasdeloup D. Dystonin/BPAG1 promotes plus-end-directed transport of herpes simplex virus 1 capsids on microtubules during entry. J Virol. 2013;87:11008-18 pubmed publisher
Shrestha R, Draviam V. Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK. Curr Biol. 2013;23:1514-26 pubmed publisher
Tarkar A, Loges N, Slagle C, Francis R, Dougherty G, Tamayo J, et al. DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013;45:995-1003 pubmed publisher
Shinohara H, Sakayori N, Takahashi M, Osumi N. Ninein is essential for the maintenance of the cortical progenitor character by anchoring the centrosome to microtubules. Biol Open. 2013;2:739-49 pubmed publisher
B renz F, Inoue D, Yokoyama H, Tegha Dunghu J, Freiss S, Draeger S, et al. The centriolar satellite protein SSX2IP promotes centrosome maturation. J Cell Biol. 2013;202:81-95 pubmed publisher
Morató L, Galino J, Ruiz M, Calingasan N, Starkov A, Dumont M, et al. Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy. Brain. 2013;136:2432-43 pubmed publisher
Hoff S, Halbritter J, Epting D, Frank V, Nguyen T, van Reeuwijk J, et al. ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nat Genet. 2013;45:951-6 pubmed publisher
Ketema M, Kreft M, Secades P, Janssen H, Sonnenberg A. Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis. Mol Biol Cell. 2013;24:2454-66 pubmed publisher
Meyer F, Ehlers E, Steadman A, Waterbury T, Cao M, Zhang L. TLR-TRIF pathway enhances the expression of KSHV replication and transcription activator. J Biol Chem. 2013;288:20435-42 pubmed publisher
Jauffred B, Llense F, Sommer B, Wang Z, Martin C, Bellaiche Y. Regulation of centrosome movements by numb and the collapsin response mediator protein during Drosophila sensory progenitor asymmetric division. Development. 2013;140:2657-68 pubmed publisher
Devaul N, Wang R, Sperry A. PPP1R42, a PP1 binding protein, regulates centrosome dynamics in ARPE-19 cells. Biol Cell. 2013;105:359-71 pubmed publisher
Nishi R, Sakai W, Tone D, Hanaoka F, Sugasawa K. Structure-function analysis of the EF-hand protein centrin-2 for its intracellular localization and nucleotide excision repair. Nucleic Acids Res. 2013;41:6917-29 pubmed publisher
Jordan N, Prat A, Abell A, Zawistowski J, Sciaky N, Karginova O, et al. SWI/SNF chromatin-remodeling factor Smarcd3/Baf60c controls epithelial-mesenchymal transition by inducing Wnt5a signaling. Mol Cell Biol. 2013;33:3011-25 pubmed publisher
Chouinard G, Clément I, Lafontaine J, Rodier F, Schmitt E. Cell cycle-dependent localization of CHK2 at centrosomes during mitosis. Cell Div. 2013;8:7 pubmed publisher
Boehlke C, Kotsis F, Buchholz B, Powelske C, Eckardt K, Walz G, et al. Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells. PLoS ONE. 2013;8:e62165 pubmed publisher
Nakamura T, Saito H, Takekawa M. SAPK pathways and p53 cooperatively regulate PLK4 activity and centrosome integrity under stress. Nat Commun. 2013;4:1775 pubmed publisher
Kress E, Schwager F, Holtackers R, Seiler J, Prodon F, Zanin E, et al. The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A. J Cell Biol. 2013;201:559-75 pubmed publisher
Basten S, Davis E, Gillis A, van Rooijen E, Stoop H, Babala N, et al. Mutations in LRRC50 predispose zebrafish and humans to seminomas. PLoS Genet. 2013;9:e1003384 pubmed publisher
Umlauf D, Bonnet J, Waharte F, Fournier M, Stierlé M, Fischer B, et al. The human TREX-2 complex is stably associated with the nuclear pore basket. J Cell Sci. 2013;126:2656-67 pubmed publisher
Wong V, Morse J, Zhitkovich A. p53 activation by Ni(II) is a HIF-1? independent response causing caspases 9/3-mediated apoptosis in human lung cells. Toxicol Appl Pharmacol. 2013;269:233-9 pubmed publisher
Koreishi M, Gniadek T, Yu S, Masuda J, Honjo Y, Satoh A. The golgin tether giantin regulates the secretory pathway by controlling stack organization within Golgi apparatus. PLoS ONE. 2013;8:e59821 pubmed publisher
Hunt S, Townley A, Danson C, Cullen P, Stephens D. Microtubule motors mediate endosomal sorting by maintaining functional domain organization. J Cell Sci. 2013;126:2493-501 pubmed publisher
Reboutier D, Troadec M, Cremet J, Chauvin L, Guen V, Salaun P, et al. Aurora A is involved in central spindle assembly through phosphorylation of Ser 19 in P150Glued. J Cell Biol. 2013;201:65-79 pubmed publisher
Lee Y, Chung S, Baek I, Lee T, Paik S, Lee J. UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis. Cell Cycle. 2013;12:1303-15 pubmed publisher
Hashimoto S, Amo A, Hama S, Ito K, Nakaoka Y, Morimoto Y. Growth retardation in human blastocysts increases the incidence of abnormal spindles and decreases implantation potential after vitrification. Hum Reprod. 2013;28:1528-35 pubmed publisher
Teodoro Morrison T, Schuiki I, Zhang L, Belsham D, Volchuk A. GRP78 overproduction in pancreatic beta cells protects against high-fat-diet-induced diabetes in mice. Diabetologia. 2013;56:1057-67 pubmed publisher
Gerhardt C, Lier J, Kuschel S, Ruther U. The ciliary protein Ftm is required for ventricular wall and septal development. PLoS ONE. 2013;8:e57545 pubmed publisher
Schober G, Arnold M, Birtles S, Buckett L, Pacheco López G, Turnbull A, et al. Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats. J Lipid Res. 2013;54:1369-84 pubmed publisher
Tiwari A, Schuiki I, Zhang L, Allister E, Wheeler M, Volchuk A. SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic ?-cells. J Cell Sci. 2013;126:1962-8 pubmed publisher
Stützer I, Selevsek N, Esterházy D, Schmidt A, Aebersold R, Stoffel M. Systematic proteomic analysis identifies ?-site amyloid precursor protein cleaving enzyme 2 and 1 (BACE2 and BACE1) substrates in pancreatic ?-cells. J Biol Chem. 2013;288:10536-47 pubmed publisher
Trakala M, Fernández Miranda G, Perez de Castro I, Heeschen C, Malumbres M. Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1). Cell Cycle. 2013;12:1030-41 pubmed publisher
Olmsted Z, Riehlman T, Branca C, Colliver A, Cruz L, Paluh J. Kinesin-14 Pkl1 targets ?-tubulin for release from the ?-tubulin ring complex (?-TuRC) ???????. Cell Cycle. 2013;12:842-8 pubmed publisher
Majumder S, Fisk H. VDAC3 and Mps1 negatively regulate ciliogenesis. Cell Cycle. 2013;12:849-58 pubmed publisher
Radtke K, English L, Rondeau C, Leib D, Lippé R, Desjardins M. Inhibition of the host translation shutoff response by herpes simplex virus 1 triggers nuclear envelope-derived autophagy. J Virol. 2013;87:3990-7 pubmed publisher
Tattikota S, Sury M, Rathjen T, Wessels H, Pandey A, You X, et al. Argonaute2 regulates the pancreatic β-cell secretome. Mol Cell Proteomics. 2013;12:1214-25 pubmed publisher
Ott C, Elia N, Jeong S, Insinna C, Sengupta P, Lippincott Schwartz J. Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts. Cilia. 2012;1:3 pubmed publisher
Oganesian L, Karlseder J. 5' C-rich telomeric overhangs are an outcome of rapid telomere truncation events. DNA Repair (Amst). 2013;12:238-45 pubmed publisher
Feijs K, Kleine H, Braczynski A, Forst A, Herzog N, Verheugd P, et al. ARTD10 substrate identification on protein microarrays: regulation of GSK3? by mono-ADP-ribosylation. Cell Commun Signal. 2013;11:5 pubmed publisher
Heideman M, Wilting R, Yanover E, Velds A, de Jong J, Kerkhoven R, et al. Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function. Blood. 2013;121:2038-50 pubmed publisher
López Erauskin J, Galino J, Bianchi P, Fourcade S, Andreu A, Ferrer I, et al. Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy. Brain. 2012;135:3584-98 pubmed publisher
Vazquez Martin A, Cufí S, Lopez Bonet E, Corominas Faja B, Oliveras Ferraros C, Martin Castillo B, et al. Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency. Sci Rep. 2012;2:964 pubmed publisher
Bubenshchikova E, Ichimura K, Fukuyo Y, Powell R, Hsu C, Morrical S, et al. Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis. Biol Open. 2012;1:588-96 pubmed publisher
Moghe S, Jiang F, Miura Y, Cerny R, Tsai M, Furukawa M. The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A. Biol Open. 2012;1:82-91 pubmed publisher
Chen Y, Colvin E, Maier B, Mirmira R, Fueger P. Mitogen-inducible gene 6 triggers apoptosis and exacerbates ER stress-induced ?-cell death. Mol Endocrinol. 2013;27:162-71 pubmed publisher
Fan C, Lum M, Xu C, Black J, Wang X. Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response. J Biol Chem. 2013;288:1674-84 pubmed publisher
Ramsey M, Perkins B. Basal bodies exhibit polarized positioning in zebrafish cone photoreceptors. J Comp Neurol. 2013;521:1803-16 pubmed publisher
Yang S, Gao C, Chen L, Song Y, Zhu J, Qi S, et al. Nek9 regulates spindle organization and cell cycle progression during mouse oocyte meiosis and its location in early embryo mitosis. Cell Cycle. 2012;11:4366-77 pubmed publisher
Estevez Garcia P, Castaño A, Martin A, Lopez Rios F, Iglesias J, Muñoz Galvan S, et al. PDGFR?/? and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome. BMC Cancer. 2012;12:514 pubmed publisher
Berbari N, Sharma N, Malarkey E, Pieczynski J, Boddu R, Gaertig J, et al. Microtubule modifications and stability are altered by cilia perturbation and in cystic kidney disease. Cytoskeleton (Hoboken). 2013;70:24-31 pubmed publisher
Rodrigue A, Coulombe Y, Jacquet K, Gagné J, Roques C, Gobeil S, et al. The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy. J Cell Sci. 2013;126:348-59 pubmed publisher
Hiruta C, Tochinai S. Spindle assembly and spatial distribution of γ-tubulin during abortive meiosis and cleavage division in the parthenogenetic water flea Daphnia pulex. Zoolog Sci. 2012;29:733-7 pubmed publisher
Kryndushkin D, Ihrke G, Piermartiri T, Shewmaker F. A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity. Mol Microbiol. 2012;86:1531-47 pubmed publisher
Wu S, Shin J, Sepich D, Solnica Krezel L. Chemokine GPCR signaling inhibits β-catenin during zebrafish axis formation. PLoS Biol. 2012;10:e1001403 pubmed publisher
Horani A, Druley T, Zariwala M, Patel A, Levinson B, Van Arendonk L, et al. Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia. Am J Hum Genet. 2012;91:685-93 pubmed publisher
Chang C, Serra R. Ift88 regulates Hedgehog signaling, Sfrp5 expression, and ?-catenin activity in post-natal growth plate. J Orthop Res. 2013;31:350-6 pubmed publisher
Cheng Y, Eley L, Hynes A, Overman L, Simms R, Barker A, et al. Investigating embryonic expression patterns and evolution of AHI1 and CEP290 genes, implicated in Joubert syndrome. PLoS ONE. 2012;7:e44975 pubmed publisher
Valente R, Ehlers E, Xu D, Ahmad H, Steadman A, Blasnitz L, et al. Toll-like receptor 7 stimulates the expression of Epstein-Barr virus latent membrane protein 1. PLoS ONE. 2012;7:e43317 pubmed publisher
Kleylein Sohn J, Pöllinger B, Ohmer M, Hofmann F, Nigg E, Hemmings B, et al. Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET. J Cell Sci. 2012;125:5391-402 pubmed publisher
Holt J, Lane S, Jennings P, Garcia Higuera I, Moreno S, Jones K. APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing. Mol Biol Cell. 2012;23:3970-81 pubmed publisher
Ozaki Y, Matsui H, Asou H, Nagamachi A, Aki D, Honda H, et al. Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation. Mol Cell. 2012;47:694-706 pubmed publisher
Hossain M, Stillman B. Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication. Genes Dev. 2012;26:1797-810 pubmed publisher
Cornacchia D, Dileep V, Quivy J, Foti R, Tili F, Santarella Mellwig R, et al. Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells. EMBO J. 2012;31:3678-90 pubmed publisher
Habermann K, Mirgorodskaya E, Gobom J, Lehmann V, Müller H, Blümlein K, et al. Functional analysis of centrosomal kinase substrates in Drosophila melanogaster reveals a new function of the nuclear envelope component otefin in cell cycle progression. Mol Cell Biol. 2012;32:3554-69 pubmed publisher
Rosa Garrido M, Ceballos L, Alonso Lecue P, Abraira C, Delgado M, Gandarillas A. A cell cycle role for the epigenetic factor CTCF-L/BORIS. PLoS ONE. 2012;7:e39371 pubmed publisher
Jakopec V, Topolski B, Fleig U. Sos7, an essential component of the conserved Schizosaccharomyces pombe Ndc80-MIND-Spc7 complex, identifies a new family of fungal kinetochore proteins. Mol Cell Biol. 2012;32:3308-20 pubmed publisher
Mukherjee S, Diaz Valencia J, Stewman S, Metz J, Monnier S, Rath U, et al. Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis. Cell Cycle. 2012;11:2359-66 pubmed publisher
Brachmann S, Kleylein Sohn J, Gaulis S, Kauffmann A, Blommers M, Kazic Legueux M, et al. Characterization of the mechanism of action of the pan class I PI3K inhibitor NVP-BKM120 across a broad range of concentrations. Mol Cancer Ther. 2012;11:1747-57 pubmed publisher
Cheval H, Guy J, Merusi C, De Sousa D, Selfridge J, Bird A. Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows. Hum Mol Genet. 2012;21:3806-14 pubmed publisher
Chiyoda T, Sugiyama N, Shimizu T, Naoe H, Kobayashi Y, Ishizawa J, et al. LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression. J Cell Biol. 2012;197:625-41 pubmed publisher
Schmitt J, Fischer U, Heisel S, Strickfaden H, Backes C, Ruggieri A, et al. GAS41 amplification results in overexpression of a new spindle pole protein. Genes Chromosomes Cancer. 2012;51:868-80 pubmed publisher
Koch A, Holaska J. Loss of emerin alters myogenic signaling and miRNA expression in mouse myogenic progenitors. PLoS ONE. 2012;7:e37262 pubmed publisher
Gomez Ferreria M, Bashkurov M, Helbig A, Larsen B, Pawson T, Gingras A, et al. Novel NEDD1 phosphorylation sites regulate ?-tubulin binding and mitotic spindle assembly. J Cell Sci. 2012;125:3745-51 pubmed publisher
Zimmermann M, Arachchige Don A, Donaldson M, Dallapiazza R, Cowan C, Horne M. Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin. J Biol Chem. 2012;287:22838-53 pubmed publisher
Watanabe T, Sakai Y, Koga D, Bochimoto H, Hira Y, Hosaka M, et al. A unique ball-shaped Golgi apparatus in the rat pituitary gonadotrope: its functional implications in relation to the arrangement of the microtubule network. J Histochem Cytochem. 2012;60:588-602 pubmed publisher
Sfeir A, de Lange T. Removal of shelterin reveals the telomere end-protection problem. Science. 2012;336:593-7 pubmed publisher
Hintermair C, Heidemann M, Koch F, Descostes N, Gut M, Gut I, et al. Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation. EMBO J. 2012;31:2784-97 pubmed publisher
Zerlanko B, Bartholin L, Melhuish T, Wotton D. Premature senescence and increased TGFβ signaling in the absence of Tgif1. PLoS ONE. 2012;7:e35460 pubmed publisher
Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, et al. Necdin controls Foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis. J Neurosci. 2012;32:5562-72 pubmed publisher
Veleri S, Bishop K, Dalle Nogare D, English M, Foskett T, Chitnis A, et al. Knockdown of Bardet-Biedl syndrome gene BBS9/PTHB1 leads to cilia defects. PLoS ONE. 2012;7:e34389 pubmed publisher
Sakai D, Dixon J, Dixon M, Trainor P. Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. PLoS Genet. 2012;8:e1002566 pubmed publisher
Sukhotnik I, Mogilner J, Pollak Y, Blumenfeld S, Bejar J, Coran A. PDGF-α stimulates intestinal epithelial cell turnover after massive small bowel resection in a rat. Am J Physiol Gastrointest Liver Physiol. 2012;302:G1274-81 pubmed publisher
Liu K, Jacobs D, Dunn B, Fanning A, Cheney R. Myosin-X functions in polarized epithelial cells. Mol Biol Cell. 2012;23:1675-87 pubmed publisher
Schottenfeld Roames J, Ghabrial A. Whacked and Rab35 polarize dynein-motor-complex-dependent seamless tube growth. Nat Cell Biol. 2012;14:386-93 pubmed publisher
Hayashi M, Cesare A, Fitzpatrick J, Lazzerini Denchi E, Karlseder J. A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest. Nat Struct Mol Biol. 2012;19:387-94 pubmed publisher
Preussner M, Schreiner S, Hung L, Porstner M, Jack H, Benes V, et al. HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing. Nucleic Acids Res. 2012;40:5666-78 pubmed publisher
Tang C, Koulajian K, Schuiki I, Zhang L, Desai T, Ivovic A, et al. Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress. Diabetologia. 2012;55:1366-79 pubmed publisher
Kee H, Dishinger J, Blasius T, Liu C, Margolis B, Verhey K. A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia. Nat Cell Biol. 2012;14:431-7 pubmed publisher
Tan L, Saijo M, Kuraoka I, Narita T, Takahata C, Iwai S, et al. Xeroderma pigmentosum group F protein binds to Eg5 and is required for proper mitosis: implications for XP-F and XFE. Genes Cells. 2012;17:173-85 pubmed publisher
Zhao H, Chen X, Gurian West M, Roberts J. Loss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication. Mol Cell Biol. 2012;32:1421-32 pubmed publisher
Kierszenbaum A, Rivkin E, Tres L. Cytoskeletal track selection during cargo transport in spermatids is relevant to male fertility. Spermatogenesis. 2011;1:221-230 pubmed
Bahtz R, Seidler J, Arnold M, Haselmann Weiss U, Antony C, Lehmann W, et al. GCP6 is a substrate of Plk4 and required for centriole duplication. J Cell Sci. 2012;125:486-96 pubmed publisher
Urbé S, Liu H, Hayes S, Heride C, Rigden D, Clague M. Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions. Mol Biol Cell. 2012;23:1095-103 pubmed publisher
Zong M, Satoh A, Yu M, Siu K, Ng W, Chan H, et al. TRAPPC9 mediates the interaction between p150 and COPII vesicles at the target membrane. PLoS ONE. 2012;7:e29995 pubmed publisher
Liu C, Bakeri H, Li T, Swaroop A. Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma. Hum Mol Genet. 2012;21:1848-60 pubmed publisher
Yang J, Wang L, Song H, Sokolov M. Current understanding of usher syndrome type II. Front Biosci (Landmark Ed). 2012;17:1165-83 pubmed
Teodoro T, Odisho T, Sidorova E, Volchuk A. Pancreatic ?-cells depend on basal expression of active ATF6?-p50 for cell survival even under nonstress conditions. Am J Physiol Cell Physiol. 2012;302:C992-1003 pubmed publisher
Westendorp B, Mokry M, Groot Koerkamp M, Holstege F, Cuppen E, de Bruin A. E2F7 represses a network of oscillating cell cycle genes to control S-phase progression. Nucleic Acids Res. 2012;40:3511-23 pubmed publisher
Li H, Xu J, Bian Y, Rotllant P, Shen T, Chu W, et al. Smyd1b_tv1, a key regulator of sarcomere assembly, is localized on the M-line of skeletal muscle fibers. PLoS ONE. 2011;6:e28524 pubmed publisher
Chang C, Ramaswamy G, Serra R. Depletion of primary cilia in articular chondrocytes results in reduced Gli3 repressor to activator ratio, increased Hedgehog signaling, and symptoms of early osteoarthritis. Osteoarthritis Cartilage. 2012;20:152-61 pubmed publisher
Montes De Oca R, Andreassen P, Wilson K. Barrier-to-Autointegration Factor influences specific histone modifications. Nucleus. 2011;2:580-90 pubmed publisher
Brown A, Nair V, Allday M. Epigenetic regulation of the latency-associated region of Marek's disease virus in tumor-derived T-cell lines and primary lymphoma. J Virol. 2012;86:1683-95 pubmed publisher
Sato K, Nishida K, Shibuya A, Siomi M, Siomi H. Maelstrom coordinates microtubule organization during Drosophila oogenesis through interaction with components of the MTOC. Genes Dev. 2011;25:2361-73 pubmed publisher
Browne G, Dickens M. Reversible translocation of ASK1 to a Triton-X100 insoluble cytoplasmic compartment during cardiac myocyte cell stress. J Recept Signal Transduct Res. 2011;31:408-15 pubmed publisher
Groocock L, Prudden J, Perry J, Boddy M. The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast. Mol Cell Biol. 2012;32:276-87 pubmed publisher
Khan J, Ezan F, Cremet J, Fautrel A, Gilot D, Lambert M, et al. Overexpression of active Aurora-C kinase results in cell transformation and tumour formation. PLoS ONE. 2011;6:e26512 pubmed publisher
Mühlhans J, Brandstätter J, Giessl A. The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors. PLoS ONE. 2011;6:e26496 pubmed publisher
Marion R, Schotta G, Ortega S, Blasco M. Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells. PLoS ONE. 2011;6:e25680 pubmed publisher
Matsumoto G, Wada K, Okuno M, Kurosawa M, Nukina N. Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Mol Cell. 2011;44:279-89 pubmed publisher
Tuson M, He M, Anderson K. Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube. Development. 2011;138:4921-30 pubmed publisher
Baron Gaillard C, Pallesi Pocachard E, Massey Harroche D, Richard F, Arsanto J, Chauvin J, et al. Hook2 is involved in the morphogenesis of the primary cilium. Mol Biol Cell. 2011;22:4549-62 pubmed publisher
Iliev D, Sobhkhez M, Fremmerlid K, J rgensen J. MyD88 interacts with interferon regulatory factor (IRF) 3 and IRF7 in Atlantic salmon (Salmo salar): transgenic SsMyD88 modulates the IRF-induced type I interferon response and accumulates in aggresomes. J Biol Chem. 2011;286:42715-24 pubmed publisher
Serio G, Margaria V, Jensen S, Oldani A, Bartek J, Bussolino F, et al. Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores. Proc Natl Acad Sci U S A. 2011;108:17337-42 pubmed publisher
Brownlee C, Klebba J, Buster D, Rogers G. The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification. J Cell Biol. 2011;195:231-43 pubmed publisher
Larkins C, Aviles G, East M, Kahn R, Caspary T. Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins. Mol Biol Cell. 2011;22:4694-703 pubmed publisher
Hubert T, Vandekerckhove J, Gettemans J. Cdk1 and BRCA1 target ?-tubulin to microtubule domains. Biochem Biophys Res Commun. 2011;414:240-5 pubmed publisher
Hellström A, WATT B, Fard S, Tenza D, Mannstrom P, Narfstrom K, et al. Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation. PLoS Genet. 2011;7:e1002285 pubmed publisher
Berbari N, Kin N, Sharma N, Michaud E, Kesterson R, Yoder B. Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation. Dev Biol. 2011;360:66-76 pubmed publisher
Lenos K, de Lange J, Teunisse A, Lodder K, Verlaan de Vries M, Wiercinska E, et al. Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts. Mol Cancer. 2011;10:111 pubmed publisher
Komatsu Y, Kaartinen V, Mishina Y. Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry. Development. 2011;138:3915-20 pubmed publisher
Costello I, Pimeisl I, Dräger S, Bikoff E, Robertson E, Arnold S. The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol. 2011;13:1084-91 pubmed publisher
Hwang H, Ji J, Jang Y. Phosphorylation of Ran-binding protein-1 by Polo-like kinase-1 is required for interaction with Ran and early mitotic progression. J Biol Chem. 2011;286:33012-20 pubmed publisher
Huertas D, Soler M, Moretó J, Villanueva A, Martinez A, Vidal A, et al. Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene. 2012;31:1408-18 pubmed publisher
Reber S. Isolation of centrosomes from cultured cells. Methods Mol Biol. 2011;777:107-16 pubmed publisher
Wu C, Guo X, Wang F, Li X, Tian X, Li L, et al. Simulated microgravity compromises mouse oocyte maturation by disrupting meiotic spindle organization and inducing cytoplasmic blebbing. PLoS ONE. 2011;6:e22214 pubmed publisher
Lackner D, Durocher D, Karlseder J. A siRNA-based screen for genes involved in chromosome end protection. PLoS ONE. 2011;6:e21407 pubmed publisher
Chen C, Lin Y, Lai Y, Chen H. ?-Adducin translocates to the nucleus upon loss of cell-cell adhesions. Traffic. 2011;12:1327-40 pubmed publisher
Greer A, Hearing P, Ketner G. The adenovirus E4 11 k protein binds and relocalizes the cytoplasmic P-body component Ddx6 to aggresomes. Virology. 2011;417:161-8 pubmed publisher
Fütterer A, Raya A, Llorente M, Izpisua Belmonte J, de la Pompa J, Klatt P, et al. Ablation of Dido3 compromises lineage commitment of stem cells in vitro and during early embryonic development. Cell Death Differ. 2012;19:132-43 pubmed publisher
Muniz V, Barnes J, Paliwal S, Zhang X, Tang X, Chen S, et al. The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis. Mol Cancer Res. 2011;9:867-77 pubmed publisher
Cecere F, Di Domenico C, Di Napoli D, Boscia F, Di Natale P. Activation of stress kinases in the brain of mucopolysaccharidosis IIIB mice. J Neurosci Res. 2011;89:1431-8 pubmed publisher
Hurtado L, Caballero C, Gavilan M, Cardenas J, Bornens M, Rios R. Disconnecting the Golgi ribbon from the centrosome prevents directional cell migration and ciliogenesis. J Cell Biol. 2011;193:917-33 pubmed publisher
Bartolomei G, Cevik R, Marcello A. Modulation of hepatitis C virus replication by iron and hepcidin in Huh7 hepatocytes. J Gen Virol. 2011;92:2072-81 pubmed publisher
Mahen R, Jeyasekharan A, Barry N, Venkitaraman A. Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis. Proc Natl Acad Sci U S A. 2011;108:9310-5 pubmed publisher
Ben Gedalya T, Lyakhovetsky R, Yedidia Y, Bejerano Sagie M, Kogan N, Karpuj M, et al. Cyclosporin-A-induced prion protein aggresomes are dynamic quality-control cellular compartments. J Cell Sci. 2011;124:1891-902 pubmed publisher
Sato S, Trackman P, Maki J, Myllyharju J, Kirsch K, Sonenshein G. The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. Mol Cell Biol. 2011;31:2683-95 pubmed publisher
von Erichsen J, Hecht W, Löhberg Gruene C, Reinacher M. Cell lines derived from feline fibrosarcoma display unstable chromosomal aneuploidy and additionally centrosome number aberrations. Vet Pathol. 2012;49:648-57 pubmed publisher
Pruliere G, Cosson J, Chevalier S, Sardet C, Chenevert J. Atypical protein kinase C controls sea urchin ciliogenesis. Mol Biol Cell. 2011;22:2042-53 pubmed publisher
Oganesian L, Karlseder J. Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance. Mol Cell. 2011;42:224-36 pubmed publisher
Hopp K, Heyer C, Hommerding C, Henke S, Sundsbak J, Patel S, et al. B9D1 is revealed as a novel Meckel syndrome (MKS) gene by targeted exon-enriched next-generation sequencing and deletion analysis. Hum Mol Genet. 2011;20:2524-34 pubmed publisher
Xu D, Meyer F, Ehlers E, Blasnitz L, Zhang L. Interferon regulatory factor 4 (IRF-4) targets IRF-5 to regulate Epstein-Barr virus transformation. J Biol Chem. 2011;286:18261-7 pubmed publisher
Galino J, Ruiz M, Fourcade S, Schluter A, López Erauskin J, Guilera C, et al. Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy. Antioxid Redox Signal. 2011;15:2095-107 pubmed publisher
Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, et al. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J. 2011;30:1520-35 pubmed publisher
Li A, Saito M, Chuang J, Tseng Y, Dedesma C, Tomizawa K, et al. Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors. Nat Cell Biol. 2011;13:402-11 pubmed publisher
Horikawa T, Yoshizaki T, Kondo S, Furukawa M, Kaizaki Y, Pagano J. Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinoma. Br J Cancer. 2011;104:1160-7 pubmed publisher
Tängemo C, Ronchi P, Colombelli J, Haselmann U, Simpson J, Antony C, et al. A novel laser nanosurgery approach supports de novo Golgi biogenesis in mammalian cells. J Cell Sci. 2011;124:978-87 pubmed publisher
Kierszenbaum A, Rivkin E, Tres L, Yoder B, Haycraft C, Bornens M, et al. GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail. Dev Dyn. 2011;240:723-36 pubmed publisher
Ward A, Morettin A, Shum D, Hudson J. Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice. BMC Cancer. 2011;11:71 pubmed publisher
Reid E, Juleff N, Gubbins S, Prentice H, Seago J, Charleston B. Bovine plasmacytoid dendritic cells are the major source of type I interferon in response to foot-and-mouth disease virus in vitro and in vivo. J Virol. 2011;85:4297-308 pubmed publisher
Franck N, Montembault E, Romé P, Pascal A, Cremet J, Giet R. CDK11(p58) is required for centriole duplication and Plk4 recruitment to mitotic centrosomes. PLoS ONE. 2011;6:e14600 pubmed publisher
Hubert T, Vandekerckhove J, Gettemans J. Unconventional actin conformations localize on intermediate filaments in mitosis. Biochem Biophys Res Commun. 2011;406:101-6 pubmed publisher
Silverman Gavrila R, Silverman Gavrila L, Hou G, Zhang M, Charlton M, Bendeck M. Rear polarization of the microtubule-organizing center in neointimal smooth muscle cells depends on PKC?, ARPC5, and RHAMM. Am J Pathol. 2011;178:895-910 pubmed publisher
Sansregret L, Vadnais C, Livingstone J, Kwiatkowski N, Awan A, Cadieux C, et al. Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure. Proc Natl Acad Sci U S A. 2011;108:1949-54 pubmed publisher
Rix S, Calmont A, Scambler P, Beales P. An Ift80 mouse model of short rib polydactyly syndromes shows defects in hedgehog signalling without loss or malformation of cilia. Hum Mol Genet. 2011;20:1306-14 pubmed publisher
Ahmad H, Gubbels R, Ehlers E, Meyer F, Waterbury T, Lin R, et al. Kaposi sarcoma-associated herpesvirus degrades cellular Toll-interleukin-1 receptor domain-containing adaptor-inducing beta-interferon (TRIF). J Biol Chem. 2011;286:7865-72 pubmed publisher
Zhang T, Yao S, Wang P, Yin C, Xiao C, Qian M, et al. ApoA-II directs morphogenetic movements of zebrafish embryo by preventing chromosome fusion during nuclear division in yolk syncytial layer. J Biol Chem. 2011;286:9514-25 pubmed publisher
Belgiovine C, Frapolli R, Bonezzi K, Chiodi I, Favero F, Mello Grand M, et al. Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells. PLoS ONE. 2010;5:e14154 pubmed publisher
Sepich D, Usmani M, Pawlicki S, Solnica Krezel L. Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements. Development. 2011;138:543-52 pubmed publisher
Zanet J, Freije A, Ruiz M, Coulon V, Sanz J, Chiesa J, et al. A mitosis block links active cell cycle with human epidermal differentiation and results in endoreplication. PLoS ONE. 2010;5:e15701 pubmed publisher
Palacios J, Herranz D, De Bonis M, Velasco S, Serrano M, Blasco M. SIRT1 contributes to telomere maintenance and augments global homologous recombination. J Cell Biol. 2010;191:1299-313 pubmed publisher
Ozaki Y, Matsui H, Nagamachi A, Asou H, Aki D, Inaba T. The dynactin complex maintains the integrity of metaphasic centrosomes to ensure transition to anaphase. J Biol Chem. 2011;286:5589-98 pubmed publisher
Wei J, Seemann J. Nakiterpiosin targets tubulin and triggers mitotic catastrophe in human cancer cells. Mol Cancer Ther. 2010;9:3375-85 pubmed publisher
Deleidi M, Hallett P, Koprich J, Chung C, Isacson O. The Toll-like receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration. J Neurosci. 2010;30:16091-101 pubmed publisher
Hubert T, Vandekerckhove J, Gettemans J. Actin and Arp2/3 localize at the centrosome of interphase cells. Biochem Biophys Res Commun. 2011;404:153-8 pubmed publisher
van Leeuwen N, Bellingrath S, de Kloet E, Zitman F, DeRijk R, Kudielka B, et al. Human mineralocorticoid receptor (MR) gene haplotypes modulate MR expression and transactivation: implication for the stress response. Psychoneuroendocrinology. 2011;36:699-709 pubmed publisher
Hatch E, Kulukian A, Holland A, Cleveland D, Stearns T. Cep152 interacts with Plk4 and is required for centriole duplication. J Cell Biol. 2010;191:721-9 pubmed publisher
Torgersen M, Engedal N, Pedersen A, Husebye H, Espevik T, Sandvig K. Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunol Med Microbiol. 2011;61:63-75 pubmed publisher
Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, et al. Primary cilia regulate mTORC1 activity and cell size through Lkb1. Nat Cell Biol. 2010;12:1115-22 pubmed publisher
Zhang Z, Lowry S, Guarente L, Haimovich B. Roles of SIRT1 in the acute and restorative phases following induction of inflammation. J Biol Chem. 2010;285:41391-401 pubmed publisher
Balasubramanian N, Bai P, Buchek G, Korza G, Weller S. Physical interaction between the herpes simplex virus type 1 exonuclease, UL12, and the DNA double-strand break-sensing MRN complex. J Virol. 2010;84:12504-14 pubmed publisher
Inanç B, Dodson H, Morrison C. A centrosome-autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage. Mol Biol Cell. 2010;21:3866-77 pubmed publisher
Teixido Travesa N, Villen J, Lacasa C, Bertran M, Archinti M, Gygi S, et al. The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8. Mol Biol Cell. 2010;21:3963-72 pubmed publisher
Bernick E, Zhang P, Du S. Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos. BMC Cell Biol. 2010;11:70 pubmed publisher
Inaba M, Yuan H, Salzmann V, Fuller M, Yamashita Y. E-cadherin is required for centrosome and spindle orientation in Drosophila male germline stem cells. PLoS ONE. 2010;5:e12473 pubmed publisher
Pulvers J, Bryk J, Fish J, Wilsch Bräuninger M, Arai Y, Schreier D, et al. Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline. Proc Natl Acad Sci U S A. 2010;107:16595-600 pubmed publisher
Montañez Wiscovich M, Shelton M, Seachrist D, Lozada K, Johnson E, Miedler J, et al. Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells. J Pathol. 2010;222:271-81 pubmed publisher
Archinti M, Lacasa C, Teixido Travesa N, Lüders J. SPICE--a previously uncharacterized protein required for centriole duplication and mitotic chromosome congression. J Cell Sci. 2010;123:3039-46 pubmed publisher
Vitte J, Traver S, Maués De Paula A, Lesage S, Rovelli G, Corti O, et al. Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease. J Neuropathol Exp Neurol. 2010;69:959-72 pubmed publisher
Vellanki R, Zhang L, Guney M, Rocheleau J, Gannon M, Volchuk A. OASIS/CREB3L1 induces expression of genes involved in extracellular matrix production but not classical endoplasmic reticulum stress response genes in pancreatic beta-cells. Endocrinology. 2010;151:4146-57 pubmed publisher
Bush J, Wevrick R. Loss of Necdin impairs myosin activation and delays cell polarization. Genesis. 2010;48:540-53 pubmed publisher
Hartley T, Siva M, Lai E, Teodoro T, Zhang L, Volchuk A. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin. BMC Cell Biol. 2010;11:59 pubmed publisher
Johns H, Doceul V, Everett H, Crooke H, Charleston B, Seago J. The classical swine fever virus N-terminal protease N(pro) binds to cellular HAX-1. J Gen Virol. 2010;91:2677-86 pubmed publisher
Recino A, Sherwood V, Flaxman A, Cooper W, Latif F, Ward A, et al. Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis. Biochem J. 2010;430:207-13 pubmed publisher
Leatherman J, Dinardo S. Germline self-renewal requires cyst stem cells and stat regulates niche adhesion in Drosophila testes. Nat Cell Biol. 2010;12:806-11 pubmed publisher
Golan A, Pick E, Tsvetkov L, Nadler Y, Kluger H, Stern D. Centrosomal Chk2 in DNA damage responses and cell cycle progression. Cell Cycle. 2010;9:2647-56 pubmed
Hu E, Fu J, Zhao P, Yao B, Qi Y, Yuan Z, et al. Diethyl sulfate induced Cdk2-dependent centrosome amplification in CHL cells. Toxicology. 2010;275:58-64 pubmed publisher
Sosa Seda I, Mott J, Akazawa Y, Barreyro F, Bronk S, Kaufmann S, et al. Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition. Hepatol Res. 2010;40:701-10 pubmed publisher
Zhang J, Wu M, Wang S, Shah J, Wilson P, Zhou J. Polycystic kidney disease protein fibrocystin localizes to the mitotic spindle and regulates spindle bipolarity. Hum Mol Genet. 2010;19:3306-19 pubmed publisher
Villasevil E, Guil S, López Ferreras L, Sanchez C, Del Val M, Anton L. Accumulation of polyubiquitylated proteins in response to Ala-Ala-Phe-chloromethylketone is independent of the inhibition of Tripeptidyl peptidase II. Biochim Biophys Acta. 2010;1803:1094-105 pubmed publisher
van Harn T, Foijer F, van Vugt M, Banerjee R, Yang F, Oostra A, et al. Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling. Genes Dev. 2010;24:1377-88 pubmed publisher
Harding S, Browne G, Miller B, Prigent S, Dickens M. Activation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemia. Biochim Biophys Acta. 2010;1802:733-40 pubmed publisher
Skalska L, White R, Franz M, Ruhmann M, Allday M. Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP. PLoS Pathog. 2010;6:e1000951 pubmed publisher
Fuchs F, Pau G, Kranz D, Sklyar O, Budjan C, Steinbrink S, et al. Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Mol Syst Biol. 2010;6:370 pubmed publisher
Mapp O, Wanner S, Rohrschneider M, Prince V. Prickle1b mediates interpretation of migratory cues during zebrafish facial branchiomotor neuron migration. Dev Dyn. 2010;239:1596-608 pubmed publisher
Mimura Y, Takahashi K, Kawata K, Akazawa T, Inoue N. Two-step colocalization of MORC3 with PML nuclear bodies. J Cell Sci. 2010;123:2014-24 pubmed publisher
Chakraborty P, Lee W, Molitor M, Wolff N, Thevenod F. Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells. Mol Cancer. 2010;9:102 pubmed publisher
Efthimiou M, Ouranou D, Stephanou G, Demopoulos N, Nikolaropoulos S, Alevizos P. Comparative study of genetic activity of chlorambucil's active metabolite steroidal esters: the role of steroidal skeleton on aneugenic potential. Mutat Res. 2010;689:1-11 pubmed publisher
Rosario C, Ko M, Haffani Y, Gladdy R, Paderova J, Pollett A, et al. Plk4 is required for cytokinesis and maintenance of chromosomal stability. Proc Natl Acad Sci U S A. 2010;107:6888-93 pubmed publisher
Keuling A, Andrew S, Tron V. Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: novel regulation of PUMA. Pigment Cell Melanoma Res. 2010;23:430-40 pubmed publisher
Mital J, Miller N, Fischer E, Hackstadt T. Specific chlamydial inclusion membrane proteins associate with active Src family kinases in microdomains that interact with the host microtubule network. Cell Microbiol. 2010;12:1235-49 pubmed publisher
Li X, Urwyler O, Suter B. Drosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation. PLoS Genet. 2010;6:e1000876 pubmed publisher
Gómez Baldó L, Schmidt S, Maxwell C, Bonifaci N, Gabaldón T, Vidalain P, et al. TACC3-TSC2 maintains nuclear envelope structure and controls cell division. Cell Cycle. 2010;9:1143-55 pubmed
Kaneko M, Koike H, Saito R, Kitamura Y, Okuma Y, Nomura Y. Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation. J Neurosci. 2010;30:3924-32 pubmed publisher
Manning J, Shalini S, Risk J, Day C, Kumar S. A direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome. PLoS ONE. 2010;5:e9618 pubmed publisher
Wen X, Lai C, Evangelista M, Hongo J, De Sauvage F, Scales S. Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation. Mol Cell Biol. 2010;30:1910-22 pubmed publisher
Manning J, Lewis M, Koblar S, Kumar S. An essential function for the centrosomal protein NEDD1 in zebrafish development. Cell Death Differ. 2010;17:1302-14 pubmed publisher
Prieto Echagüe V, Gucwa A, Craddock B, Brown D, Miller W. Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1. J Biol Chem. 2010;285:10605-15 pubmed publisher
Yamada M, Udagawa J, Matsumoto A, Hashimoto R, Hatta T, Nishita M, et al. Ror2 is required for midgut elongation during mouse development. Dev Dyn. 2010;239:941-53 pubmed publisher
Meyer Morse N, Robbins J, Rae C, Mochegova S, Swanson M, Zhao Z, et al. Listeriolysin O is necessary and sufficient to induce autophagy during Listeria monocytogenes infection. PLoS ONE. 2010;5:e8610 pubmed publisher
Codina M, Li J, Gutierrez J, Kao J, Du S. Loss of Smyhc1 or Hsp90alpha1 function results in different effects on myofibril organization in skeletal muscles of zebrafish embryos. PLoS ONE. 2010;5:e8416 pubmed publisher
Begemann S, Galimi F, Karlseder J. Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas. Aging (Albany NY). 2009;1:122-130 pubmed
Kotani T, Iemura S, Natsume T, Kawakami K, Yamashita M. Mys protein regulates protein kinase A activity by interacting with regulatory type Ialpha subunit during vertebrate development. J Biol Chem. 2010;285:5106-16 pubmed publisher
Otero J, Suo J, Gordon C, Chang E. Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation. Cell Cycle. 2010;9:147-61 pubmed
Fant X, Srsen V, Espigat Georger A, Merdes A. Nuclei of non-muscle cells bind centrosome proteins upon fusion with differentiating myoblasts. PLoS ONE. 2009;4:e8303 pubmed publisher
Cho E, Whipple R, Matrone M, Balzer E, Martin S. Delocalization of gamma-tubulin due to increased solubility in human breast cancer cell lines. Cancer Biol Ther. 2010;9:66-76 pubmed
Kibe T, Osawa G, Keegan C, de Lange T. Telomere protection by TPP1 is mediated by POT1a and POT1b. Mol Cell Biol. 2010;30:1059-66 pubmed publisher
Dumont N, Crawford Y, Sigaroudinia M, Nagrani S, Wilson M, Buehring G, et al. Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy. Breast Cancer Res. 2009;11:R87 pubmed publisher
Buffone M, Schindler K, Schultz R. Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos. Cell Cycle. 2009;8:3904-13 pubmed
Andersen N, Yeaman C. Sec3-containing exocyst complex is required for desmosome assembly in mammalian epithelial cells. Mol Biol Cell. 2010;21:152-64 pubmed publisher
Amato A, Lentini L, Schillaci T, Iovino F, Di Leonardo A. RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation. BMC Cell Biol. 2009;10:79 pubmed publisher
Alexandrova E, Sokol S. Xenopus axin-related protein: a link between its centrosomal localization and function in the Wnt/beta-catenin pathway. Dev Dyn. 2010;239:261-70 pubmed publisher
Rath U, Rogers G, Tan D, Gomez Ferreria M, Buster D, Sosa H, et al. The Drosophila kinesin-13, KLP59D, impacts Pacman- and Flux-based chromosome movement. Mol Biol Cell. 2009;20:4696-705 pubmed publisher
Difilippantonio M, Ghadimi B, Howard T, Camps J, Nguyen Q, Ferris D, et al. Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells. Environ Mol Mutagen. 2009;50:672-96 pubmed publisher
Montes De Oca R, Shoemaker C, Gucek M, Cole R, Wilson K. Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners. PLoS ONE. 2009;4:e7050 pubmed publisher
Fishman Jacob T, Reznichenko L, Youdim M, Mandel S. A sporadic Parkinson disease model via silencing of the ubiquitin-proteasome/E3 ligase component SKP1A. J Biol Chem. 2009;284:32835-45 pubmed publisher
Cadieux C, Kedinger V, Yao L, Vadnais C, Drossos M, Paquet M, et al. Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types. Cancer Res. 2009;69:7188-97 pubmed publisher
Masuoka H, MOTT J, Bronk S, Werneburg N, Akazawa Y, Kaufmann S, et al. Mcl-1 degradation during hepatocyte lipoapoptosis. J Biol Chem. 2009;284:30039-48 pubmed publisher
Keuling A, Felton K, Parker A, Akbari M, Andrew S, Tron V. RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway. PLoS ONE. 2009;4:e6651 pubmed publisher
Wainman A, Buster D, Duncan T, Metz J, Ma A, Sharp D, et al. A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes. Genes Dev. 2009;23:1876-81 pubmed publisher
Yamashita T, Liu J, Gao J, LeNoue S, Wang C, Kaminoh J, et al. Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa. J Neurosci. 2009;29:9748-60 pubmed publisher
Sheng X, Posenau T, Gumulak Smith J, Matunis E, Van Doren M, Wawersik M. Jak-STAT regulation of male germline stem cell establishment during Drosophila embryogenesis. Dev Biol. 2009;334:335-44 pubmed publisher
Aoki T, Ueda S, Kataoka T, Satoh T. Regulation of mitotic spindle formation by the RhoA guanine nucleotide exchange factor ARHGEF10. BMC Cell Biol. 2009;10:56 pubmed publisher
Cerezo A, Guadamillas M, Goetz J, Sánchez Perales S, Klein E, Assoian R, et al. The absence of caveolin-1 increases proliferation and anchorage- independent growth by a Rac-dependent, Erk-independent mechanism. Mol Cell Biol. 2009;29:5046-59 pubmed publisher
Alam G, Cui H, Shi H, Yang L, Ding J, Mao L, et al. MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development. Am J Pathol. 2009;175:856-66 pubmed publisher
Schilling S, Hjelmeland A, Radiloff D, Liu I, Wakeman T, Fielhauer J, et al. NDRG4 is required for cell cycle progression and survival in glioblastoma cells. J Biol Chem. 2009;284:25160-9 pubmed publisher
Bellmann K, Charette S, Nadeau P, Poirier D, Loranger A, Landry J. The mechanism whereby heat shock induces apoptosis depends on the innate sensitivity of cells to stress. Cell Stress Chaperones. 2010;15:101-13 pubmed publisher
Paschos K, Smith P, Anderton E, Middeldorp J, White R, Allday M. Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene Bim. PLoS Pathog. 2009;5:e1000492 pubmed publisher
Haren L, Stearns T, Lüders J. Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components. PLoS ONE. 2009;4:e5976 pubmed publisher
Rivkin E, Kierszenbaum A, Gil M, Tres L. Rnf19a, a ubiquitin protein ligase, and Psmc3, a component of the 26S proteasome, tether to the acrosome membranes and the head-tail coupling apparatus during rat spermatid development. Dev Dyn. 2009;238:1851-61 pubmed publisher
Kingeter L, Schaefer B. Expanding the multicolor capabilities of basic confocal microscopes by employing red and near-infrared quantum dot conjugates. BMC Biotechnol. 2009;9:49 pubmed publisher
Mota L, Ramsden A, Liu M, Castle J, Holden D. SCAMP3 is a component of the Salmonella-induced tubular network and reveals an interaction between bacterial effectors and post-Golgi trafficking. Cell Microbiol. 2009;11:1236-53 pubmed publisher
Katsura M, Tsuruga T, Date O, Yoshihara T, Ishida M, Tomoda Y, et al. The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction. Nucleic Acids Res. 2009;37:3959-68 pubmed publisher
Anderson M, Jodoin J, Lee E, Hales K, Hays T, Lee L. Asunder is a critical regulator of dynein-dynactin localization during Drosophila spermatogenesis. Mol Biol Cell. 2009;20:2709-21 pubmed publisher
Peterson Roth E, Brdlik C, Glazer P. Src-Induced cisplatin resistance mediated by cell-to-cell communication. Cancer Res. 2009;69:3619-24 pubmed publisher
Kasbek C, Yang C, Fisk H. Mps1 as a link between centrosomes and genomic instability. Environ Mol Mutagen. 2009;50:654-65 pubmed publisher
Wilkinson C, Carl M, Harris W. Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. BMC Cell Biol. 2009;10:17 pubmed publisher
Rivero S, Cardenas J, Bornens M, Rios R. Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130. EMBO J. 2009;28:1016-28 pubmed publisher
Jiang H, Wu J, He C, Yang W, Li H. Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation. Cell Res. 2009;19:458-68 pubmed publisher
Bialas N, Inglis P, Li C, Robinson J, Parker J, Healey M, et al. Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins. J Cell Sci. 2009;122:611-24 pubmed publisher
Gong Y, Sun Y, McNutt M, Sun Q, Hou L, Liu H, et al. Localization of TEIF in the centrosome and its functional association with centrosome amplification in DNA damage, telomere dysfunction and human cancers. Oncogene. 2009;28:1549-60 pubmed publisher
Sánchez Cañete M, Carvalho L, Pérez Victoria F, Gamarro F, Castanys S. Low plasma membrane expression of the miltefosine transport complex renders Leishmania braziliensis refractory to the drug. Antimicrob Agents Chemother. 2009;53:1305-13 pubmed publisher
Zhang G, Breuer M, Förster A, Egger Adam D, Wodarz A. Mars, a Drosophila protein related to vertebrate HURP, is required for the attachment of centrosomes to the mitotic spindle during syncytial nuclear divisions. J Cell Sci. 2009;122:535-45 pubmed publisher
Rogers G, Rusan N, Roberts D, Peifer M, Rogers S. The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication. J Cell Biol. 2009;184:225-39 pubmed publisher
de Jesus Perez V, Alastalo T, Wu J, Axelrod J, Cooke J, Amieva M, et al. Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol. 2009;184:83-99 pubmed publisher
Naslavsky N, McKenzie J, Altan Bonnet N, Sheff D, Caplan S. EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology. J Cell Sci. 2009;122:389-400 pubmed publisher
Schindler K, Schultz R. CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes. Biol Reprod. 2009;80:795-803 pubmed publisher
Keller L, Geimer S, Romijn E, Yates J, Zamora I, Marshall W. Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control. Mol Biol Cell. 2009;20:1150-66 pubmed publisher
Netherton C, Simpson J, Haller O, Wileman T, Takamatsu H, Monaghan P, et al. Inhibition of a large double-stranded DNA virus by MxA protein. J Virol. 2009;83:2310-20 pubmed publisher
Yi X, de Vries H, Siudeja K, Rana A, Lemstra W, Brunsting J, et al. Stwl modifies chromatin compaction and is required to maintain DNA integrity in the presence of perturbed DNA replication. Mol Biol Cell. 2009;20:983-94 pubmed publisher
Omran H, Kobayashi D, Olbrich H, Tsukahara T, Loges N, Hagiwara H, et al. Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. Nature. 2008;456:611-6 pubmed publisher
Lagresle Peyrou C, Six E, Picard C, Rieux Laucat F, Michel V, Ditadi A, et al. Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness. Nat Genet. 2009;41:106-11 pubmed publisher
Zhu H, Coppinger J, Jang C, Yates J, Fang G. FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. J Cell Biol. 2008;183:835-48 pubmed publisher
Houben F, Willems C, Declercq I, Hochstenbach K, Kamps M, Snoeckx L, et al. Disturbed nuclear orientation and cellular migration in A-type lamin deficient cells. Biochim Biophys Acta. 2009;1793:312-24 pubmed publisher
Yu Y, Pace S, Allen S, Deng C, Hsu L. A PP1-binding motif present in BRCA1 plays a role in its DNA repair function. Int J Biol Sci. 2008;4:352-61 pubmed
Cheng J, Turkel N, Hemati N, Fuller M, Hunt A, Yamashita Y. Centrosome misorientation reduces stem cell division during ageing. Nature. 2008;456:599-604 pubmed publisher
Kobayashi Y, Yonehara S. Novel cell death by downregulation of eEF1A1 expression in tetraploids. Cell Death Differ. 2009;16:139-50 pubmed publisher
Venoux M, Delmouly K, Milhavet O, Vidal Eychenié S, Giorgi D, Rouquier S. Gene organization, evolution and expression of the microtubule-associated protein ASAP (MAP9). BMC Genomics. 2008;9:406 pubmed publisher
Moshnikova A, Kuznetsov S, Khokhlatchev A. Interaction of the growth and tumour suppressor NORE1A with microtubules is not required for its growth-suppressive function. BMC Res Notes. 2008;1:13 pubmed publisher
Savage A, Constantinides M, Han J, Picard D, Martin E, Li B, et al. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity. 2008;29:391-403 pubmed publisher
Shtutman M, Chausovsky A, Prager Khoutorsky M, Schiefermeier N, Boguslavsky S, Kam Z, et al. Signaling function of alpha-catenin in microtubule regulation. Cell Cycle. 2008;7:2377-83 pubmed
Miyagi E, Schwartzkopff F, Plishka R, Buckler White A, Clouse K, Strebel K. APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages. Virology. 2008;379:266-74 pubmed publisher
Lombaert I, Brunsting J, Wierenga P, Kampinga H, de Haan G, Coppes R. Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool. Stem Cells. 2008;26:2595-601 pubmed publisher
Rai R, Phadnis A, Haralkar S, Badwe R, Dai H, Li K, et al. Differential regulation of centrosome integrity by DNA damage response proteins. Cell Cycle. 2008;7:2225-33 pubmed
Ji J, Jang Y. Functional independency between catalytic activity and subcellular targeting of polo-like kinase-1: phenotypes of ectopic overexpression of various mutants. Cell Cycle. 2008;7:1597-603 pubmed
Strom A, Shi P, Zhang F, Gal J, Kilty R, Hayward L, et al. Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation. J Biol Chem. 2008;283:22795-805 pubmed publisher
Yi X, Lemstra W, Vos M, Shang Y, Kampinga H, Su T, et al. A long-term flow cytometry assay to analyze the role of specific genes of Drosophila melanogaster S2 cells in surviving genotoxic stress. Cytometry A. 2008;73:637-42 pubmed publisher
Zwerger M, Herrmann H, Gaines P, Olins A, Olins D. Granulocytic nuclear differentiation of lamin B receptor-deficient mouse EPRO cells. Exp Hematol. 2008;36:977-87 pubmed publisher
Basak S, Jacobs S, Krieg A, Pathak N, Zeng Q, Kaldis P, et al. The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation. Mol Cell. 2008;30:303-14 pubmed publisher
Rodriguez A, Batac J, Killilea A, Filopei J, Simeonov D, Lin I, et al. Protein complexes at the microtubule organizing center regulate bipolar spindle assembly. Cell Cycle. 2008;7:1246-53 pubmed
Rivkin E, Tres L, Kierszenbaum A. Genomic origin, processing and developmental expression of testicular outer dense fiber 2 (ODF2) transcripts and a novel nucleolar localization of ODF2 protein. Mol Reprod Dev. 2008;75:1591-606 pubmed publisher
Ueda Y, Koya T, Yoneda Kato N, Kato J. Small mitochondrial ARF (smARF) is located in both the nucleus and cytoplasm, induces cell death, and activates p53 in mouse fibroblasts. FEBS Lett. 2008;582:1459-64 pubmed publisher
Teodoro T, Zhang L, Alexander T, Yue J, Vranic M, Volchuk A. Oleanolic acid enhances insulin secretion in pancreatic beta-cells. FEBS Lett. 2008;582:1375-80 pubmed publisher
Fourcade S, López Erauskin J, Galino J, Duval C, Naudi A, Jove M, et al. Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy. Hum Mol Genet. 2008;17:1762-73 pubmed publisher
de Nigris F, Rossiello R, Schiano C, Arra C, Williams Ignarro S, Barbieri A, et al. Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis. Cancer Res. 2008;68:1797-808 pubmed publisher
Callé A, Ugrinova I, Epstein A, Bouvet P, Diaz J, Greco A. Nucleolin is required for an efficient herpes simplex virus type 1 infection. J Virol. 2008;82:4762-73 pubmed publisher
Sherwood V, Manbodh R, Sheppard C, Chalmers A. RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis. Mol Biol Cell. 2008;19:1772-82 pubmed publisher
Jiang Y, Xu D, Zhao Y, Zhang L. Mutual inhibition between Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus lytic replication initiators in dually-infected primary effusion lymphoma. PLoS ONE. 2008;3:e1569 pubmed publisher
Lai E, Bikopoulos G, Wheeler M, Rozakis Adcock M, Volchuk A. Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells. Am J Physiol Endocrinol Metab. 2008;294:E540-50 pubmed publisher
Hutt K, Shi Z, Albertini D, Petroff B. The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts morphogenesis of the rat pre-implantation embryo. BMC Dev Biol. 2008;8:1 pubmed publisher
Takai H, Wang R, Takai K, Yang H, de Lange T. Tel2 regulates the stability of PI3K-related protein kinases. Cell. 2007;131:1248-59 pubmed
Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, Cantley L, et al. Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. J Cell Biol. 2007;179:1133-40 pubmed
Lundin V, Srayko M, Hyman A, Leroux M. Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans. Dev Biol. 2008;313:320-34 pubmed
Cheng T, Hsiao Y, Lin C, Yu C, Hsu C, Chang M, et al. Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin. J Biol Chem. 2008;283:2454-64 pubmed
Montembault E, Dutertre S, Prigent C, Giet R. PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores. J Cell Biol. 2007;179:601-9 pubmed
Archambault V, Zhao X, White Cooper H, Carpenter A, Glover D. Mutations in Drosophila Greatwall/Scant reveal its roles in mitosis and meiosis and interdependence with Polo kinase. PLoS Genet. 2007;3:e200 pubmed
Shani G, Fischer W, Justice N, Kelber J, Vale W, Gray P. GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth. Mol Cell Biol. 2008;28:666-77 pubmed
Yoneda Kato N, Kato J. Shuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformation. Mol Cell Biol. 2008;28:422-34 pubmed
Graser S, Stierhof Y, Lavoie S, Gassner O, Lamla S, Le Clech M, et al. Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol. 2007;179:321-30 pubmed
Lajoie P, Partridge E, Guay G, Goetz J, Pawling J, Lagana A, et al. Plasma membrane domain organization regulates EGFR signaling in tumor cells. J Cell Biol. 2007;179:341-56 pubmed
Milliken E, Lozada K, Johnson E, Landis M, Seachrist D, Whitten I, et al. Ovarian hyperstimulation induces centrosome amplification and aneuploid mammary tumors independently of alterations in p53 in a transgenic mouse model of breast cancer. Oncogene. 2008;27:1759-66 pubmed
Eriksson D, Löfroth P, Johansson L, Riklund K, Stigbrand T. Cell cycle disturbances and mitotic catastrophes in HeLa Hep2 cells following 2.5 to 10 Gy of ionizing radiation. Clin Cancer Res. 2007;13:5501s-5508s pubmed
Lucas E, Raff J. Maintaining the proper connection between the centrioles and the pericentriolar matrix requires Drosophila centrosomin. J Cell Biol. 2007;178:725-32 pubmed
Schneider L, Essmann F, Kletke A, Rio P, Hanenberg H, Wetzel W, et al. The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival. J Biol Chem. 2007;282:29273-83 pubmed
Thein K, Kleylein Sohn J, Nigg E, Gruneberg U. Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. J Cell Biol. 2007;178:345-54 pubmed
Ruiz Perez V, Blair H, Rodriguez Andres M, Blanco M, Wilson A, Liu Y, et al. Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007;134:2903-12 pubmed
Anderton E, Yee J, Smith P, Crook T, White R, Allday M. Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma. Oncogene. 2008;27:421-33 pubmed publisher
Pandey R, Heeger S, Lehner C. Rapid effects of acute anoxia on spindle kinetochore interactions activate the mitotic spindle checkpoint. J Cell Sci. 2007;120:2807-18 pubmed
Yoshimura S, Egerer J, Fuchs E, Haas A, Barr F. Functional dissection of Rab GTPases involved in primary cilium formation. J Cell Biol. 2007;178:363-9 pubmed
Ando Y, Yasuda S, Oceguera Yanez F, Narumiya S. Inactivation of Rho GTPases with Clostridium difficile toxin B impairs centrosomal activation of Aurora-A in G2/M transition of HeLa cells. Mol Biol Cell. 2007;18:3752-63 pubmed
Barreyro F, Kobayashi S, Bronk S, Werneburg N, Malhi H, Gores G. Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis. J Biol Chem. 2007;282:27141-54 pubmed
Xie H, Holmes A, Wise S, Huang S, Peng C, Wise J. Neoplastic transformation of human bronchial cells by lead chromate particles. Am J Respir Cell Mol Biol. 2007;37:544-52 pubmed
White D, Caswell P, Norman J. alpha v beta3 and alpha5beta1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration. J Cell Biol. 2007;177:515-25 pubmed
Malhi H, Barreyro F, Isomoto H, Bronk S, Gores G. Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity. Gut. 2007;56:1124-31 pubmed
Zhang D, Rogers G, Buster D, Sharp D. Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes. J Cell Biol. 2007;177:231-42 pubmed
Rusan N, Peifer M. A role for a novel centrosome cycle in asymmetric cell division. J Cell Biol. 2007;177:13-20 pubmed
Nie D, Ma Q, Law J, Chia C, Dhingra N, Shimoda Y, et al. Oligodendrocytes regulate formation of nodes of Ranvier via the recognition molecule OMgp. Neuron Glia Biol. 2006;2:151-64 pubmed
Robert A, Margall Ducos G, Guidotti J, Bregerie O, Celati C, Brechot C, et al. The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells. J Cell Sci. 2007;120:628-37 pubmed
Mussmann R, Geese M, Harder F, Kegel S, Andag U, Lomow A, et al. Inhibition of GSK3 promotes replication and survival of pancreatic beta cells. J Biol Chem. 2007;282:12030-7 pubmed
Szebenyi G, Hall B, Yu R, Hashim A, KRAMER H. Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function. Traffic. 2007;8:32-46 pubmed
Arachchige Don A, Dallapiazza R, Bennin D, Brake T, Cowan C, Horne M. Cyclin G2 is a centrosome-associated nucleocytoplasmic shuttling protein that influences microtubule stability and induces a p53-dependent cell cycle arrest. Exp Cell Res. 2006;312:4181-204 pubmed
Tompkins V, Hagen J, Frazier A, Lushnikova T, Fitzgerald M, Di Tommaso A, et al. A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability. J Biol Chem. 2007;282:1322-33 pubmed
Verdun R, Karlseder J. The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell. 2006;127:709-20 pubmed
Stern K, Visser Smit G, Place T, Winistorfer S, Piper R, Lill N. Epidermal growth factor receptor fate is controlled by Hrs tyrosine phosphorylation sites that regulate Hrs degradation. Mol Cell Biol. 2007;27:888-98 pubmed
DeRijk R, Wüst S, Meijer O, Zennaro M, Federenko I, Hellhammer D, et al. A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness. J Clin Endocrinol Metab. 2006;91:5083-9 pubmed
Schmitt E, Boutros R, Froment C, Monsarrat B, Ducommun B, Dozier C. CHK1 phosphorylates CDC25B during the cell cycle in the absence of DNA damage. J Cell Sci. 2006;119:4269-75 pubmed
Eng C, Huckaba T, Gundersen G. The formin mDia regulates GSK3beta through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts. Mol Biol Cell. 2006;17:5004-16 pubmed
Reiter R, Gais P, Jutting U, Steuer Vogt M, Pickhard A, Bink K, et al. Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma. Clin Cancer Res. 2006;12:5136-41 pubmed
Basto R, Lau J, Vinogradova T, Gardiol A, Woods C, Khodjakov A, et al. Flies without centrioles. Cell. 2006;125:1375-86 pubmed
Ogburn K, Figueiredo Pereira M. Cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin J2 parallels centrosomal deposition of ubiquitinated protein aggregates. J Biol Chem. 2006;281:23274-84 pubmed
Katsetos C, Reddy G, Dráberová E, Smejkalová B, Del Valle L, Ashraf Q, et al. Altered cellular distribution and subcellular sorting of gamma-tubulin in diffuse astrocytic gliomas and human glioblastoma cell lines. J Neuropathol Exp Neurol. 2006;65:465-77 pubmed
Wong J, Fang G. HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture. J Cell Biol. 2006;173:879-91 pubmed
Gatt M, Glover D. The Drosophila phosphatidylinositol transfer protein encoded by vibrator is essential to maintain cleavage-furrow ingression in cytokinesis. J Cell Sci. 2006;119:2225-35 pubmed
Ma Z, Izumi H, Kanai M, Kabuyama Y, Ahn N, Fukasawa K. Mortalin controls centrosome duplication via modulating centrosomal localization of p53. Oncogene. 2006;25:5377-90 pubmed
Hsu L, Huang X, Seasholtz S, Potter D, Gollin S. Gene amplification and overexpression of protein phosphatase 1alpha in oral squamous cell carcinoma cell lines. Oncogene. 2006;25:5517-26 pubmed
Karaskov E, Scott C, Zhang L, Teodoro T, Ravazzola M, Volchuk A. Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis. Endocrinology. 2006;147:3398-407 pubmed
McCue S, Dajnowiec D, Xu F, Zhang M, Jackson M, Langille B. Shear stress regulates forward and reverse planar cell polarity of vascular endothelium in vivo and in vitro. Circ Res. 2006;98:939-46 pubmed
Verollet C, Colombié N, Daubon T, Bourbon H, Wright M, Raynaud Messina B. Drosophila melanogaster gamma-TuRC is dispensable for targeting gamma-tubulin to the centrosome and microtubule nucleation. J Cell Biol. 2006;172:517-28 pubmed
Haren L, Remy M, Bazin I, Callebaut I, Wright M, Merdes A. NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. J Cell Biol. 2006;172:505-15 pubmed
Richardson D, Lai A, Mulligan L. RET ligand-induced internalization and its consequences for downstream signaling. Oncogene. 2006;25:3206-11 pubmed
Matsumoto G, Kim S, Morimoto R. Huntingtin and mutant SOD1 form aggregate structures with distinct molecular properties in human cells. J Biol Chem. 2006;281:4477-85 pubmed
Reilein A, Yamada S, Nelson W. Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells. J Cell Biol. 2005;171:845-55 pubmed
Hanisch A, Wehner A, Nigg E, Sillje H. Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting. Mol Biol Cell. 2006;17:448-59 pubmed
Caron E, Charbonneau R, Huppé G, Brochu S, Perreault C. The structure and location of SIMP/STT3B account for its prominent imprint on the MHC I immunopeptidome. Int Immunol. 2005;17:1583-96 pubmed
Matsumoto G, Stojanovic A, Holmberg C, Kim S, Morimoto R. Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates. J Cell Biol. 2005;171:75-85 pubmed
Bahe S, Stierhof Y, Wilkinson C, Leiss F, Nigg E. Rootletin forms centriole-associated filaments and functions in centrosome cohesion. J Cell Biol. 2005;171:27-33 pubmed
Barros T, Kinoshita K, Hyman A, Raff J. Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. J Cell Biol. 2005;170:1039-46 pubmed
Pugacheva E, Golemis E. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat Cell Biol. 2005;7:937-46 pubmed
Ivanova I, D Souza S, Dagnino L. E2F1 stability is regulated by a novel-PKC/p38beta MAP kinase signaling pathway during keratinocyte differentiation. Oncogene. 2006;25:430-7 pubmed
Tsuchihara K, Lapin V, Bakal C, Okada H, Brown L, Hirota Tsuchihara M, et al. Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner. Cancer Res. 2005;65:6685-91 pubmed
Wonsey D, Follettie M. Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe. Cancer Res. 2005;65:5181-9 pubmed
Kim H, Kang J, Yumura S, Walsh C, Cho J, Lee J. De novo formation of basal bodies in Naegleria gruberi: regulation by phosphorylation. J Cell Biol. 2005;169:719-24 pubmed
Hut H, Kampinga H, Sibon O. Hsp70 protects mitotic cells against heat-induced centrosome damage and division abnormalities. Mol Biol Cell. 2005;16:3776-85 pubmed
Okada Y, Takeda S, Tanaka Y, Belmonte J, Hirokawa N. Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination. Cell. 2005;121:633-644 pubmed publisher
Lesca C, Germanier M, Raynaud Messina B, Pichereaux C, Etievant C, Emond S, et al. DNA damage induce gamma-tubulin-RAD51 nuclear complexes in mammalian cells. Oncogene. 2005;24:5165-72 pubmed
de Vries H, Uyetake L, Lemstra W, Brunsting J, Su T, Kampinga H, et al. Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable. J Cell Sci. 2005;118:1833-42 pubmed
Peterson Roth E, Reynolds M, Quievryn G, Zhitkovich A. Mismatch repair proteins are activators of toxic responses to chromium-DNA damage. Mol Cell Biol. 2005;25:3596-607 pubmed
Orstavik S, Funderud A, Hafte T, Eikvar S, Jahnsen T, Skålhegg B. Identification and characterization of novel PKA holoenzymes in human T lymphocytes. FEBS J. 2005;272:1559-67 pubmed
Vries R, Bezrookove V, Zuijderduijn L, Kia S, Houweling A, Oruetxebarria I, et al. Cancer-associated mutations in chromatin remodeler hSNF5 promote chromosomal instability by compromising the mitotic checkpoint. Genes Dev. 2005;19:665-70 pubmed
Dodge J, Okano M, Dick F, Tsujimoto N, Chen T, Wang S, et al. Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J Biol Chem. 2005;280:17986-91 pubmed
La Terra S, English C, Hergert P, McEwen B, Sluder G, Khodjakov A. The de novo centriole assembly pathway in HeLa cells: cell cycle progression and centriole assembly/maturation. J Cell Biol. 2005;168:713-22 pubmed
Fukumoto A, Tomoda K, Kubota M, Kato J, Yoneda Kato N. Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation. FEBS Lett. 2005;579:1047-54 pubmed
Chang C, Ma Y, Jacobs S, Tian X, Yang X, Rasmussen T. A maternal store of macroH2A is removed from pronuclei prior to onset of somatic macroH2A expression in preimplantation embryos. Dev Biol. 2005;278:367-80 pubmed
Pandey R, Heidmann S, Lehner C. Epithelial re-organization and dynamics of progression through mitosis in Drosophila separase complex mutants. J Cell Sci. 2005;118:733-42 pubmed
Nishimura T, Takahashi M, Kim H, Mukai H, Ono Y. Centrosome-targeting region of CG-NAP causes centrosome amplification by recruiting cyclin E-cdk2 complex. Genes Cells. 2005;10:75-86 pubmed
Samejima I, Lourenco P, Snaith H, Sawin K. Fission yeast mto2p regulates microtubule nucleation by the centrosomin-related protein mto1p. Mol Biol Cell. 2005;16:3040-51 pubmed
Patzke S, Hauge H, Sioud M, Finne E, Sivertsen E, Delabie J, et al. Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization. Oncogene. 2005;24:1159-73 pubmed
Gillingham A, Tong A, Boone C, Munro S. The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi. J Cell Biol. 2004;167:281-92 pubmed
Raynaud Messina B, Mazzolini L, Moisand A, Cirinesi A, Wright M. Elongation of centriolar microtubule triplets contributes to the formation of the mitotic spindle in gamma-tubulin-depleted cells. J Cell Sci. 2004;117:5497-507 pubmed
Hansen D, Loktev A, Ban K, Jackson P. Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1. Mol Biol Cell. 2004;15:5623-34 pubmed
Mahjoub M, Qasim Rasi M, Quarmby L. A NIMA-related kinase, Fa2p, localizes to a novel site in the proximal cilia of Chlamydomonas and mouse kidney cells. Mol Biol Cell. 2004;15:5172-86 pubmed
Pan H, Zhou F, Gao S. Kaposi's sarcoma-associated herpesvirus induction of chromosome instability in primary human endothelial cells. Cancer Res. 2004;64:4064-8 pubmed
Martinez Campos M, Basto R, Baker J, Kernan M, Raff J. The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis. J Cell Biol. 2004;165:673-83 pubmed
Katoh Y, Fujimoto M, Nakamura K, Inouye S, Sugahara K, Izu H, et al. Hsp25, a member of the Hsp30 family, promotes inclusion formation in response to stress. FEBS Lett. 2004;565:28-32 pubmed
Dutertre S, Cazales M, Quaranta M, Froment C, Trabut V, Dozier C, et al. Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci. 2004;117:2523-31 pubmed
Sawin K, Lourenco P, Snaith H. Microtubule nucleation at non-spindle pole body microtubule-organizing centers requires fission yeast centrosomin-related protein mod20p. Curr Biol. 2004;14:763-75 pubmed
Cohen D, Brennwald P, Rodriguez Boulan E, Müsch A. Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton. J Cell Biol. 2004;164:717-27 pubmed
Cassimeris L, Morabito J. TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly. Mol Biol Cell. 2004;15:1580-90 pubmed
Imai Y, Soda M, Murakami T, Shoji M, Abe K, Takahashi R. A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. J Biol Chem. 2003;278:51901-10 pubmed
Kilmartin J. Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication. J Cell Biol. 2003;162:1211-21 pubmed
Duensing S, Lee B, Dal Cin P, Munger K. Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma. Mol Cancer. 2003;2:30 pubmed
Goshima G, Vale R. The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line. J Cell Biol. 2003;162:1003-16 pubmed
Raemaekers T, Ribbeck K, Beaudouin J, Annaert W, van Camp M, Stockmans I, et al. NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization. J Cell Biol. 2003;162:1017-29 pubmed
Ardley H, Scott G, Rose S, Tan N, Markham A, Robinson P. Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin. Mol Biol Cell. 2003;14:4541-56 pubmed
Kronenwett U, Castro J, Roblick U, Fujioka K, Ostring C, Faridmoghaddam F, et al. Expression of cyclins A, E and topoisomerase II alpha correlates with centrosome amplification and genomic instability and influences the reliability of cytometric S-phase determination. BMC Cell Biol. 2003;4:8 pubmed
Maxwell C, Keats J, Crainie M, Sun X, Yen T, Shibuya E, et al. RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability. Mol Biol Cell. 2003;14:2262-76 pubmed
Khodjakov A, Copenagle L, Gordon M, Compton D, Kapoor T. Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis. J Cell Biol. 2003;160:671-83 pubmed
Swenson K, Winkler K, Means A. A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization. Mol Biol Cell. 2003;14:156-72 pubmed
Tsvetkov L, Xu X, Li J, Stern D. Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody. J Biol Chem. 2003;278:8468-75 pubmed
Quintyne N, Schroer T. Distinct cell cycle-dependent roles for dynactin and dynein at centrosomes. J Cell Biol. 2002;159:245-54 pubmed
Khodjakov A, Rieder C, Sluder G, Cassels G, Sibon O, Wang C. De novo formation of centrosomes in vertebrate cells arrested during S phase. J Cell Biol. 2002;158:1171-81 pubmed
Herzig A, Lehner C, Heidmann S. Proteolytic cleavage of the THR subunit during anaphase limits Drosophila separase function. Genes Dev. 2002;16:2443-54 pubmed
Littlepage L, Ruderman J. Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit. Genes Dev. 2002;16:2274-85 pubmed
Weaver Z, Montagna C, Xu X, Howard T, Gadina M, Brodie S, et al. Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer. Oncogene. 2002;21:5097-107 pubmed
Fujita A, Vardy L, Garcia M, Toda T. A fourth component of the fission yeast gamma-tubulin complex, Alp16, is required for cytoplasmic microtubule integrity and becomes indispensable when gamma-tubulin function is compromised. Mol Biol Cell. 2002;13:2360-73 pubmed
Kaiser B, Zimmerman Z, Charbonneau H, Jackson P. Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase. Mol Biol Cell. 2002;13:2289-300 pubmed
Borel F, Lohez O, Lacroix F, Margolis R. Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells. Proc Natl Acad Sci U S A. 2002;99:9819-24 pubmed
Illing M, Rajan R, Bence N, Kopito R. A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system. J Biol Chem. 2002;277:34150-60 pubmed
Chadwick B, Willard H. Cell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosome. J Cell Biol. 2002;157:1113-23 pubmed
Sulimenko V, Sulimenko T, Poznanovic S, Nechiporuk Zloy V, Böhm K, Macurek L, et al. Association of brain gamma-tubulins with alpha beta-tubulin dimers. Biochem J. 2002;365:889-95 pubmed
Jang Y, Lin C, Ma S, Erikson R. Functional studies on the role of the C-terminal domain of mammalian polo-like kinase. Proc Natl Acad Sci U S A. 2002;99:1984-9 pubmed
Linhartova I, Novotna B, Sulimenko V, Dráberová E, Draber P. Gamma-tubulin in chicken erythrocytes: changes in localization during cell differentiation and characterization of cytoplasmic complexes. Dev Dyn. 2002;223:229-40 pubmed
Giet R, McLean D, Descamps S, Lee M, Raff J, Prigent C, et al. Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J Cell Biol. 2002;156:437-51 pubmed
Seidman M, Hogan S, Wendland R, Worgall S, Crystal R, Leopold P. Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle. Mol Ther. 2001;4:13-21 pubmed
Jung M, Prigozhina N, Oakley C, Nogales E, Oakley B. Alanine-scanning mutagenesis of Aspergillus gamma-tubulin yields diverse and novel phenotypes. Mol Biol Cell. 2001;12:2119-36 pubmed
de Carcer G, do Carmo Avides M, Lallena M, Glover D, Gonzalez C. Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability. EMBO J. 2001;20:2878-84 pubmed
Khodjakov A, Rieder C. Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression. J Cell Biol. 2001;153:237-42 pubmed
Zhang L, Keating T, Wilde A, Borisy G, Zheng Y. The role of Xgrip210 in gamma-tubulin ring complex assembly and centrosome recruitment. J Cell Biol. 2000;151:1525-36 pubmed
Gunawardane R, Martin O, Cao K, Zhang L, Dej K, Iwamatsu A, et al. Characterization and reconstitution of Drosophila gamma-tubulin ring complex subunits. J Cell Biol. 2000;151:1513-24 pubmed
Gergely F, Karlsson C, Still I, Cowell J, Kilmartin J, Raff J. The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. Proc Natl Acad Sci U S A. 2000;97:14352-7 pubmed
Mayor T, Stierhof Y, Tanaka K, Fry A, Nigg E. The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion. J Cell Biol. 2000;151:837-46 pubmed
Murphy K, Dennis A, Rosen J. A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model. FASEB J. 2000;14:2291-302 pubmed
Rasmussen T, Mastrangelo M, Eden A, Pehrson J, Jaenisch R. Dynamic relocalization of histone MacroH2A1 from centrosomes to inactive X chromosomes during X inactivation. J Cell Biol. 2000;150:1189-98 pubmed
Gergely F, Kidd D, Jeffers K, Wakefield J, Raff J. D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo. EMBO J. 2000;19:241-52 pubmed
Freed E, Lacey K, Huie P, Lyapina S, Deshaies R, Stearns T, et al. Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. Genes Dev. 1999;13:2242-57 pubmed
Johnston J, Ward C, Kopito R. Aggresomes: a cellular response to misfolded proteins. J Cell Biol. 1998;143:1883-98 pubmed
Martin O, Gunawardane R, Iwamatsu A, Zheng Y. Xgrip109: a gamma tubulin-associated protein with an essential role in gamma tubulin ring complex (gammaTuRC) assembly and centrosome function. J Cell Biol. 1998;141:675-87 pubmed
product information
Product No. :
T6557
Product Name :
Monoclonal Anti-γ-Tubulin antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
GTU-88
Applications/Description :
Suitable for immunocytochemistry: 1:5,000-1:10,000 using HeLa cells; western blot: 1:10,000 using cultured chicken fibroblast extract; indirect ELISA
Species Reactivity :
Xenopus, canine, chicken, hamster, rat, human, bovine, mouse
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA