product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-τ (Tau) antibody produced in mouse
catalog :
T5530
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Tau-2
reactivity :
human, mouse, chicken, bovine
application :
western blot
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; fig 3
Lee I, Jung K, Kim I, Lee H, Kim M, Yun S, et al. Human neural stem cells alleviate Alzheimer-like pathology in a mouse model. Mol Neurodegener. 2015;10:38 pubmed publisher
Wang S, Cho Y. Yeast surface display of full-length human microtubule-associated protein tau. Biotechnol Prog. 2020;36:e2920 pubmed publisher
Mietelska Porowska A, Gasiorowska A, Palasz E, Koss D, Riedel G, Niewiadomska G. Pore-former enabled seeding of tau in rats: Alleviation by memantine and lithium chloride. J Neurosci Methods. 2019;319:47-59 pubmed publisher
Fields J, Metcalf J, OVERK C, Adame A, Spencer B, Wrasidlo W, et al. The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration. J Neurovirol. 2017;23:290-303 pubmed publisher
Pintus D, Cancedda M, Macciocu S, Contu C, Ligios C. Pathological findings in a Dachshund-cross dog with neuroaxonal dystrophy. Acta Vet Scand. 2016;58:37 pubmed publisher
Nourbakhsh N, Soleimani M, Taghipour Z, Karbalaie K, Mousavi S, Talebi A, et al. Induced in vitro differentiation of neural-like cells from human exfoliated deciduous teeth-derived stem cells. Int J Dev Biol. 2011;55:189-95 pubmed publisher
Schofield E, Hodges J, Macdonald V, Cordato N, Kril J, Halliday G. Cortical atrophy differentiates Richardson's syndrome from the parkinsonian form of progressive supranuclear palsy. Mov Disord. 2011;26:256-63 pubmed publisher
Shapiro L, Bialowas McGoey L, Whitaker Azmitia P. Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model. Cardiovasc Psychiatry Neurol. 2010;2010: pubmed publisher
Alladi S, Xuereb J, Bak T, Nestor P, Knibb J, Patterson K, et al. Focal cortical presentations of Alzheimer's disease. Brain. 2007;130:2636-45 pubmed
Halliday G, Macdonald V, Henderson J. A comparison of degeneration in motor thalamus and cortex between progressive supranuclear palsy and Parkinson's disease. Brain. 2005;128:2272-80 pubmed
Davies R, Hodges J, Kril J, Patterson K, Halliday G, Xuereb J. The pathological basis of semantic dementia. Brain. 2005;128:1984-95 pubmed
Broe M, Kril J, Halliday G. Astrocytic degeneration relates to the severity of disease in frontotemporal dementia. Brain. 2004;127:2214-20 pubmed
Guo H, Albrecht S, Bourdeau M, Petzke T, Bergeron C, LeBlanc A. Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease. Am J Pathol. 2004;165:523-31 pubmed
Broe M, Shepherd C, Milward E, Halliday G. Relationship between DNA fragmentation, morphological changes and neuronal loss in Alzheimer's disease and dementia with Lewy bodies. Acta Neuropathol. 2001;101:616-24 pubmed
Cullen K, Halliday G, Caine D, Kril J. The nucleus basalis (Ch4) in the alcoholic Wernicke-Korsakoff syndrome: reduced cell number in both amnesic and non-amnesic patients. J Neurol Neurosurg Psychiatry. 1997;63:315-20 pubmed
Hely M, Reid W, Halliday G, McRitchie D, Leicester J, Joffe R, et al. Diffuse Lewy body disease: clinical features in nine cases without coexistent Alzheimer's disease. J Neurol Neurosurg Psychiatry. 1996;60:531-8 pubmed
Papasozomenos S, Binder L. Phosphorylation determines two distinct species of Tau in the central nervous system. Cell Motil Cytoskeleton. 1987;8:210-26 pubmed
product information
Product No. :
T5530
Product Name :
Monoclonal Anti-τ (Tau) antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
TAU-2
Applications/Description :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections); western blot: 1:1,000 using a fresh total bovine brain extract or an enriched microtubule protein preparation; microarray
Species Reactivity :
human, monkey, chicken, bovine
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA