This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Triciribine hydrate
catalog :
T3830
citations: 133
Reference
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Yu L, Park B, Ahn Y, Lee G, Kim S. Hydrogen sulfide donor, NaHS, stimulates ANP secretion via the KATP channel and the NOS/sGC pathway in rat atria. Peptides. 2019;111:89-97 pubmed publisher
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Shoucri B, Hung V, Chamorro Garcia R, Shioda T, Blumberg B. Retinoid X Receptor Activation During Adipogenesis of Female Mesenchymal Stem Cells Programs a Dysfunctional Adipocyte. Endocrinology. 2018;159:2863-2883 pubmed publisher
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Das D, Zhang S, Noh I. Synthesis and characterizations of alginate-α-tricalcium phosphate microparticle hybrid film with flexibility and high mechanical property as a biomaterial. Biomed Mater. 2018;13:025008 pubmed publisher
Jeon S, Kim S, Shin S, Lee Y. Clozapine reduces Toll-like receptor 4/NF-?B-mediated inflammatory responses through inhibition of calcium/calmodulin-dependent Akt activation in microglia. Prog Neuropsychopharmacol Biol Psychiatry. 2018;81:477-487 pubmed publisher
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Long X, Gerbing R, Alonzo T, Redell M. Distinct signaling events promote resistance to mitoxantrone and etoposide in pediatric AML: a Children's Oncology Group report. Oncotarget. 2017;8:90037-90049 pubmed publisher
Nag T, Kumar P, Wadhwa S. Age related distribution of 4-hydroxy 2-nonenal immunoreactivity in human retina. Exp Eye Res. 2017;165:125-135 pubmed publisher
Sanchez C, Molinski S, Gongora R, Sosulski M, Fuselier T, Mackinnon S, et al. The Antiretroviral Agent Nelfinavir Mesylate: A Potential Therapy for Systemic Sclerosis. Arthritis Rheumatol. 2017;: pubmed publisher
Liu J, Tian Y, Ding Y, Heng D, Xu K, Liu W, et al. Role of CYP51 in the Regulation of T3 and FSH-Induced Steroidogenesis in Female Mice. Endocrinology. 2017;158:3974-3987 pubmed publisher
Bai M, Li W, Yu N, Zhang H, Long F, Zeng A. The crosstalk between β-catenin signaling and type I, type II and type III interferons in lung cancer cells. Am J Transl Res. 2017;9:2788-2797 pubmed
Linnemann A, Blumer J, Marasco M, Battiola T, Umhoefer H, Han J, et al. Interleukin 6 protects pancreatic ? cells from apoptosis by stimulation of autophagy. FASEB J. 2017;31:4140-4152 pubmed publisher
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Nicholas D, Zhang K, Hung C, Glasgow S, Aruni A, Unternaehrer J, et al. Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β. PLoS ONE. 2017;12:e0176793 pubmed publisher
De la Varga Martínez R, Rodríguez Bayona B, Añez G, Medina Varo F, Pérez Venegas J, Brieva J, et al. Clinical relevance of circulating anti-ENA and anti-dsDNA secreting cells from SLE patients and their dependence on STAT-3 activation. Eur J Immunol. 2017;47:1211-1219 pubmed publisher
Tang H, Song X, Ling Y, Wang X, Yang P, Luo T, et al. Puerarin attenuates myocardial hypoxia/reoxygenation injury by inhibiting autophagy via the Akt signaling pathway. Mol Med Rep. 2017;15:3747-3754 pubmed publisher
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Tian Y, Ding Y, Liu J, Heng D, Xu K, Liu W, et al. Nitric Oxide-Mediated Regulation of GLUT by T3 and Follicle-Stimulating Hormone in Rat Granulosa Cells. Endocrinology. 2017;158:1898-1915 pubmed publisher
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Dai Y, Jin S, Li X, Wang D. The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer. Oncotarget. 2017;8:1354-1368 pubmed publisher
Miftahussurur M, Syam A, Nusi I, Makmun D, Waskito L, Zein L, et al. Surveillance of Helicobacter pylori Antibiotic Susceptibility in Indonesia: Different Resistance Types among Regions and with Novel Genetic Mutations. PLoS ONE. 2016;11:e0166199 pubmed publisher
Yan X, Liu J, Zhang Z, Li W, Sun S, Zhao J, et al. Low-level laser irradiation modulates brain-derived neurotrophic factor mRNA transcription through calcium-dependent activation of the ERK/CREB pathway. Lasers Med Sci. 2017;32:169-180 pubmed publisher
Furuhashi T, Sakamoto K. Regulation of AKT activity prevents autonomic nervous system imbalance. Physiol Behav. 2017;168:20-23 pubmed publisher
Wang S, Lu Q, Guo Y, Song Y, Liu P, Wang Y. The blockage of Notch signalling promoted the generation of polymorphonuclear myeloid-derived suppressor cells with lower immunosuppression. Eur J Cancer. 2016;68:90-105 pubmed publisher
Kemppainen K, Wentus N, Lassila T, Laiho A, Törnquist K. Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner. Cell Signal. 2016;28:1894-1903 pubmed publisher
Kaliszczak M, Trousil S, Ali T, Aboagye E. AKT activation controls cell survival in response to HDAC6 inhibition. Cell Death Dis. 2016;7:e2286 pubmed publisher
Huang L, Liu L, Liu J, Dou L, Wang G, Liu X, et al. Ginsenoside Rg1 protects against neurodegeneration by inducing neurite outgrowth in cultured hippocampal neurons. Neural Regen Res. 2016;11:319-25 pubmed publisher
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Yang L, Sui W, Li Y, Qi X, Wang Y, Zhou Q, et al. Substance P Inhibits Hyperosmotic Stress-Induced Apoptosis in Corneal Epithelial Cells through the Mechanism of Akt Activation and Reactive Oxygen Species Scavenging via the Neurokinin-1 Receptor. PLoS ONE. 2016;11:e0149865 pubmed publisher
Cao X, Yang F, Shi T, Yuan M, Xin Z, Xie R, et al. Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis activates Akt signaling to ameliorate hepatic steatosis. Sci Rep. 2016;6:21592 pubmed publisher
Lu Q, Yan S, Sun H, Wang W, Li Y, Yang X, et al. Akt inhibition attenuates rasfonin-induced autophagy and apoptosis through the glycolytic pathway in renal cancer cells. Cell Death Dis. 2015;6:e2005 pubmed publisher
Chen W, Padilla M, Xu X, Desai D, Krzeminski J, Amin S, et al. Quercetin inhibits multiple pathways involved in interleukin 6 secretion from human lung fibroblasts and activity in bronchial epithelial cell transformation induced by benzo[a]pyrene diol epoxide. Mol Carcinog. 2016;55:1858-1866 pubmed publisher
Kaida K, Honda Y, Hashimoto Y, Tanaka M, Baba S. Application of Green Tea Catechin for Inducing the Osteogenic Differentiation of Human Dedifferentiated Fat Cells in Vitro. Int J Mol Sci. 2015;16:27988-8000 pubmed publisher
Bhargavan B, Woollard S, Kanmogne G. Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication. Cell Signal. 2016;28:7-22 pubmed publisher
Li Q, Zhang D, Chen X, He L, Li T, Xu X, et al. Nuclear PKM2 contributes to gefitinib resistance via upregulation of STAT3 activation in colorectal cancer. Sci Rep. 2015;5:16082 pubmed publisher
Amigo Jiménez I, Bailón E, Aguilera Montilla N, Terol M, García Marco J, García Pardo A. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways. Oncotarget. 2015;6:44832-48 pubmed publisher
Nagaoka A, Yoshida H, Nakamura S, Morikawa T, Kawabata K, Kobayashi M, et al. Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID (Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199) and HA Synthases in Growth Factor-stimulated Fibroblasts. J Biol Chem. 2015;290:30910-23 pubmed publisher
Harbort C, Soeiro Pereira P, von Bernuth H, Kaindl A, Costa Carvalho B, Condino Neto A, et al. Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis. Blood. 2015;126:2842-51 pubmed publisher
Klokk T, Kavaliauskiene S, Sandvig K. Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic. Cell Mol Life Sci. 2016;73:1301-16 pubmed publisher
Han F, Zhang S, Hou N, Wang D, Sun X. Irisin improves endothelial function in obese mice through the AMPK-eNOS pathway. Am J Physiol Heart Circ Physiol. 2015;309:H1501-8 pubmed publisher
Weiss R, Laengle J, Sachet M, Shurygina A, Kiselev O, Egorov A, et al. Interleukin-24 inhibits influenza A virus replication in vitro through induction of toll-like receptor 3 dependent apoptosis. Antiviral Res. 2015;123:93-104 pubmed publisher
Tactacan C, Phua Y, Liu L, Zhang L, Humphrey E, Cowley M, et al. The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling. Mol Cancer. 2015;14:139 pubmed publisher
Zhang S, Miao D, Tan L, Liu A, Lu W. Comparative cytotoxic and genotoxic potential of 13 drinking water disinfection by-products using a microplate-based cytotoxicity assay and a developed SOS/umu assay. Mutagenesis. 2016;31:35-41 pubmed publisher
Li Q, Li Y, Gu B, Fang L, Zhou P, Bao S, et al. Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation. J Biol Chem. 2015;290:21553-67 pubmed publisher
Mavroeidis L, Sheldon H, Briasoulis E, Marselos M, Pappas P, Harris A. Metronomic vinorelbine: Anti-angiogenic activity in vitro in normoxic and severe hypoxic conditions, and severe hypoxia-induced resistance to its anti-proliferative effect with reversal by Akt inhibition. Int J Oncol. 2015;47:455-64 pubmed publisher
Faludi T, Balogh C, Serfozo Z, Molnár Perl I. Analysis of phenolic compounds in the dissolved and suspended phases of Lake Balaton water by gas chromatography-tandem mass spectrometry. Environ Sci Pollut Res Int. 2015;22:11966-74 pubmed publisher
Lee H, Noh K, Lee Y, Song K, Oh S, Kim S, et al. NANOG signaling promotes metastatic capability of immunoedited tumor cells. Clin Exp Metastasis. 2015;32:429-39 pubmed publisher
Kanayasu Toyoda T, Tanaka T, Ishii Watabe A, Kitagawa H, Matsuyama A, Uchida E, et al. Angiogenic Role of MMP-2/9 Expressed on the Cell Surface of Early Endothelial Progenitor Cells/Myeloid Angiogenic Cells. J Cell Physiol. 2015;230:2763-75 pubmed publisher
Huang L, Jiang X, Gong L, Xing D. Photoactivation of Akt1/GSK3β Isoform-Specific Signaling Axis Promotes Pancreatic β-Cell Regeneration. J Cell Biochem. 2015;116:1741-54 pubmed publisher
Kulkarni N, Yi Z, Huehnken C, Agerberth B, Gudmundsson G. Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways. Mol Immunol. 2015;63:530-9 pubmed
Izumi Y, Zorumski C. Sensitivity of N-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials and synaptic plasticity to TCN 201 and TCN 213 in rat hippocampal slices. J Pharmacol Exp Ther. 2015;352:267-73 pubmed publisher
Schmetterer K, Neunkirchner A, Wojta Stremayr D, Leitner J, Steinberger P, Pickl W. STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells. FASEB J. 2015;29:759-71 pubmed publisher
Huang J, Yang Y, Yang J, Li X. Regenerating gene family member 4 promotes growth and migration of gastric cancer through protein kinase B pathway. Int J Clin Exp Med. 2014;7:3037-44 pubmed
Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil R, et al. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015;99:48-55 pubmed publisher
Richards M, Narasipura S, Kim S, Seaton M, Lutgen V, Al Harthi L. Dynamic interaction between astrocytes and infiltrating PBMCs in context of neuroAIDS. Glia. 2015;63:441-51 pubmed publisher
Li S, Dang Y, Oi Lam Che G, Kwan Y, Chan S, Leung G, et al. VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation. Toxicol Appl Pharmacol. 2014;280:408-20 pubmed publisher
Liu J, He J, Huang L, Dou L, Wu S, Yuan Q. Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury and neurite outgrowth. Neural Regen Res. 2014;9:943-50 pubmed publisher
Shimura T, Noma N, Sano Y, Ochiai Y, Oikawa T, Fukumoto M, et al. AKT-mediated enhanced aerobic glycolysis causes acquired radioresistance by human tumor cells. Radiother Oncol. 2014;112:302-7 pubmed publisher
Anderson J, Titz B, Akiyama R, Komisopoulou E, Park A, Tap W, et al. Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors. Mol Cancer Res. 2014;12:1740-54 pubmed publisher
Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed publisher
Jiang H, Cheng X, Shi G, Hu L, Inoue A, Yamamura Y, et al. Cathepsin K-mediated Notch1 activation contributes to neovascularization in response to hypoxia. Nat Commun. 2014;5:3838 pubmed publisher
Gong J, Muñoz A, Chan D, Ghosh R, Kumar A. STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth. Oncotarget. 2014;5:2529-41 pubmed
Noh K, Kim S, Kim J, Song K, Lee Y, Kang T, et al. API5 confers tumoral immune escape through FGF2-dependent cell survival pathway. Cancer Res. 2014;74:3556-66 pubmed publisher
Liu L, Detering J, Milde T, Haefeli W, Witt O, Burhenne J. Quantification of vorinostat and its main metabolites in plasma and intracellular vorinostat in PBMCs by liquid chromatography coupled to tandem mass spectrometry and its relation to histone deacetylase activity in human blood. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;964:212-21 pubmed publisher
Honzawa Y, Nakase H, Shiokawa M, Yoshino T, Imaeda H, Matsuura M, et al. Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease. Gut. 2014;63:1902-12 pubmed publisher
Forkwa T, Neumann I, Tamm E, Ohlmann A, Reber S. Short-term psychosocial stress protects photoreceptors from damage via corticosterone-mediated activation of the AKT pathway. Exp Neurol. 2014;252:28-36 pubmed publisher
Darr J, Klochendler A, Isaac S, Eden A. Loss of IGFBP7 expression and persistent AKT activation contribute to SMARCB1/Snf5-mediated tumorigenesis. Oncogene. 2014;33:3024-32 pubmed publisher
Liu T, Wang P, Cong M, Xu Y, Jia J, You H. The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism. Biosci Rep. 2013;33: pubmed publisher
Hrstka R, Murray E, Brychtova V, Fabian P, Hupp T, Vojtesek B. Identification of an AKT-dependent signalling pathway that mediates tamoxifen-dependent induction of the pro-metastatic protein anterior gradient-2. Cancer Lett. 2013;333:187-93 pubmed publisher
Huang L, Tang Y, Xing D. Activation of nuclear estrogen receptors induced by low-power laser irradiation via PI3-K/Akt signaling cascade. J Cell Physiol. 2013;228:1045-59 pubmed publisher
Yang K, Tseng Y, Nerbonne J. Exercise training and PI3Kα-induced electrical remodeling is independent of cellular hypertrophy and Akt signaling. J Mol Cell Cardiol. 2012;53:532-41 pubmed publisher
Wang Q, Li S, Wang H, Xiao Y, Sahin O, Brady S, et al. Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer. Cancer Res. 2012;72:4417-28 pubmed
Littlepage L, Adler A, Kouros Mehr H, Huang G, Chou J, Krig S, et al. The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discov. 2012;2:638-51 pubmed publisher
Henning R, Dennis S, Sawmiller D, Hunter L, Sanberg P, Miller L. Human umbilical cord blood mononuclear cells activate the survival protein Akt in cardiac myocytes and endothelial cells that limits apoptosis and necrosis during hypoxia. Transl Res. 2012;159:497-506 pubmed publisher
Hou J, Wang L. FKBP5 as a selection biomarker for gemcitabine and Akt inhibitors in treatment of pancreatic cancer. PLoS ONE. 2012;7:e36252 pubmed publisher
Mersmann J, Tran N, Latsch K, Habeck K, Iskandar F, Zimmermann R, et al. Akt or phosphoinositide-3-kinase inhibition reverses cardio-protection in Toll-like receptor 2 deficient mice. Resuscitation. 2012;83:1404-10 pubmed publisher
Lee Y, Lee S, Park J, Kim R, Kim S, Roh K, et al. Dysadherin expression promotes the motility and survival of human breast cancer cells by AKT activation. Cancer Sci. 2012;103:1280-9 pubmed publisher
Gloesenkamp C, Nitzsche B, Ocker M, Di Fazio P, Quint K, Hoffmann B, et al. AKT inhibition by triciribine alone or as combination therapy for growth control of gastroenteropancreatic neuroendocrine tumors. Int J Oncol. 2012;40:876-88 pubmed publisher
Neasta J, Ben Hamida S, Yowell Q, Carnicella S, Ron D. AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors. Biol Psychiatry. 2011;70:575-82 pubmed publisher
Nava P, Capaldo C, Koch S, Kolegraff K, Rankin C, Farkas A, et al. JAM-A regulates epithelial proliferation through Akt/?-catenin signalling. EMBO Rep. 2011;12:314-20 pubmed publisher
Chang C, Au L, Huang S, Fai Kwok C, Ho L, Juan C. Insulin up-regulates heme oxygenase-1 expression in 3T3-L1 adipocytes via PI3-kinase- and PKC-dependent pathways and heme oxygenase-1-associated microRNA downregulation. Endocrinology. 2011;152:384-93 pubmed publisher
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product information
Catalog Number :
T3830
Product Name :
Triciribine hydrate
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥97% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA