This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Tyrphostin AG 490
catalog :
T3434
citations: 14
Reference
Kurowska P, Mlyczynska E, Dawid M, Opydo Chanek M, Dupont J, Rak A. In Vitro Effects of Vaspin on Porcine Granulosa Cell Proliferation, Cell Cycle Progression, and Apoptosis by Activation of GRP78 Receptor and Several Kinase Signaling Pathways Including MAP3/1, AKT, and STAT3. Int J Mol Sci. 2019;20: pubmed publisher
Silva C, Correia Branco A, Andrade N, Ferreira A, Soares M, Sonveaux P, et al. Selective pro-apoptotic and antimigratory effects of polyphenol complex catechin:lysine 1:2 in breast, pancreatic and colorectal cancer cell lines. Eur J Pharmacol. 2019;859:172533 pubmed publisher
Sung P, Rama N, Imbach J, Fiore S, Ducarouge B, Neves D, et al. Cancer-associated fibroblasts produce Netrin-1 to control cancer cell plasticity. Cancer Res. 2019;: pubmed publisher
Kurowska P, Mlyczynska E, Barbe A, Staub C, Gregoraszczuk E, Dupont J, et al. Vaspin in the pig ovarian follicles: expression and regulation by different hormones. Reproduction. 2019;158:135-146 pubmed publisher
Zhang Q, Lee W, Kang J, Kim L, Kim Y. Integrin CD11b negatively regulates Mincle-induced signaling via the Lyn-SIRPα-SHP1 complex. Exp Mol Med. 2018;50:e439 pubmed publisher
Lau W, Zhu X, Ho S, Chang S, Ding J. Combinatorial treatment with polyI:C and anti-IL6 enhances apoptosis and suppresses metastasis of lung cancer cells. Oncotarget. 2017;8:32884-32904 pubmed publisher
Geng T, Lv D, Huang Y, Hou C, Qin G, Guo X. JAK/STAT signaling pathway-mediated immune response in silkworm (Bombyx mori) challenged by Beauveria bassiana. Gene. 2016;595:69-76 pubmed publisher
Park S, Kim J, Oh C, Choi S, Jeon J, Lee I. Scoparone interferes with STAT3-induced proliferation of vascular smooth muscle cells. Exp Mol Med. 2015;47:e145 pubmed publisher
Liu D, Ji L, Tong X, Pan B, Han J, Huang Y, et al. Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1. Am J Physiol Cell Physiol. 2011;301:C739-48 pubmed publisher
Polikov V, Hong J, Reichert W. Soluble factor effects on glial cell reactivity at the surface of gel-coated microwires. J Neurosci Methods. 2010;190:180-7 pubmed publisher
Eriksen K, Kaltoft K, Mikkelsen G, Nielsen M, Zhang Q, Geisler C, et al. Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells. Leukemia. 2001;15:787-93 pubmed
Abe J, Berk B. Fyn and JAK2 mediate Ras activation by reactive oxygen species. J Biol Chem. 1999;274:21003-10 pubmed
Al Shami A, Naccache P. Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase. J Biol Chem. 1999;274:5333-8 pubmed
Potier B, Rovira C. Protein tyrosine kinase inhibitors reduce high-voltage activating calcium currents in CA1 pyramidal neurones from rat hippocampal slices. Brain Res. 1999;816:587-97 pubmed
product information
Catalog Number :
T3434
Product Name :
Tyrphostin AG 490
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA