Wang W, Jiang Z, Wang L, Wang A, Liu J, Chen C, et al. All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase. Cancer Lett. 2020;473:130-138 pubmed publisher

Nkongolo S, Nußbaum L, Lempp F, Wodrich H, Urban S, Ni Y. The retinoic acid receptor (RAR) α-specific agonist Am80 (tamibarotene) and other RAR agonists potently inhibit hepatitis B virus transcription from cccDNA. Antiviral Res. 2019;168:146-155 pubmed publisher

Hattori H, Ishikawa Y, Kawashima N, Akashi A, Yamaguchi Y, Harada Y, et al. Identification of the novel deletion-type PML-RARA mutation associated with the retinoic acid resistance in acute promyelocytic leukemia. PLoS ONE. 2018;13:e0204850 pubmed publisher

Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, et al. MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1. Nat Med. 2017;23:723-732 pubmed publisher

Naskar D, Teng F, Felix K, Bradley C, WU H. Synthetic Retinoid AM80 Ameliorates Lung and Arthritic Autoimmune Responses by Inhibiting T Follicular Helper and Th17 Cell Responses. J Immunol. 2017;198:1855-1864 pubmed publisher

Duprey Díaz M, Blagburn J, Blanco R. Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System after Optic Nerve Injury. PLoS ONE. 2016;11:e0162626 pubmed publisher

Zhang Y, Zuo Q, Liu Z, Li D, Tang B, Xiao T, et al. The Induction Effect of Am80 and TSA on ESC Differentiation via Regulation of Stra8 in Chicken. PLoS ONE. 2015;10:e0140262 pubmed publisher

Kubben N, Brimacombe K, Donegan M, Li Z, Misteli T. A high-content imaging-based screening pipeline for the systematic identification of anti-progeroid compounds. Methods. 2016;96:46-58 pubmed publisher

Sanford D, Lo Coco F, Sanz M, Di Bona E, Coutre S, Altman J, et al. Tamibarotene in patients with acute promyelocytic leukaemia relapsing after treatment with all-trans retinoic acid and arsenic trioxide. Br J Haematol. 2015;171:471-7 pubmed publisher

Seo G, Jang Y, Kim J, Choe J, Han H, Lee J, et al. Retinoic acid acts as a selective human IgA switch factor. Hum Immunol. 2014;75:923-9 pubmed publisher

Rothwell C, Spencer G. Retinoid signaling is necessary for, and promotes long-term memory formation following operant conditioning. Neurobiol Learn Mem. 2014;114:127-40 pubmed publisher

Lv X, Zheng B, Li S, Han A, Wang C, Shi J, et al. Synthetic retinoid Am80 up-regulates apelin expression by promoting interaction of RARα with KLF5 and Sp1 in vascular smooth muscle cells. Biochem J. 2013;456:35-46 pubmed publisher

Liu X, Wang Z, Feng R, Hu Y, Huang G. A novel approach for systematic delivery of a hydrophobic anti-leukemia agent tamibarotene mediated by nanostructured lipid carrier. J Biomed Nanotechnol. 2013;9:1586-93 pubmed

Fujita H, Asou N, Iwanaga M, Hyo R, Nomura S, Kiyoi H, et al. Role of hematopoietic stem cell transplantation for relapsed acute promyelocytic leukemia: a retrospective analysis of JALSG-APL97. Cancer Sci. 2013;104:1339-45 pubmed publisher

Kitaoka K, Shimizu N, Ono K, Chikahisa S, Nakagomi M, Shudo K, et al. The retinoic acid receptor agonist Am80 increases hippocampal ADAM10 in aged SAMP8 mice. Neuropharmacology. 2013;72:58-65 pubmed publisher

Yoshikawa O, Ebata Y, Tsuchiya H, Kawahara A, Kojima C, Ikeda Y, et al. A retinoic acid receptor agonist tamibarotene suppresses iron accumulation in the liver. Obesity (Silver Spring). 2013;21:E22-5 pubmed publisher

Nakagomi M, Shudo K, Nakatani Pawlak A. Synthetic retinoid Am80 results in improved exploratory and emotional behavior in the P8 substrain of senescence-accelerated mice. Pharmacol Biochem Behav. 2013;104:1-9 pubmed publisher

Ding W, Shimada H, Li L, Mittal R, Zhang X, Shudo K, et al. Retinoid agonist Am80-enhanced neutrophil bactericidal activity arising from granulopoiesis in vitro and in a neutropenic mouse model. Blood. 2013;121:996-1007 pubmed publisher

Miyabe C, Miyabe Y, Miura N, Takahashi K, Terashima Y, Toda E, et al. Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation. Arthritis Rheum. 2013;65:503-12 pubmed publisher

Emi N. [Management of relapsed acute promyelocytic leukemia]. Nihon Rinsho. 2012;70 Suppl 2:420-4 pubmed

Shiohira H, Kitaoka A, Enjoji M, Uno T, Nakashima M. Am80 induces neuronal differentiation via increased tropomyosin-related kinase B expression in a human neuroblastoma SH-SY5Y cell line. Biomed Res. 2012;33:291-7 pubmed

Fukasawa H, Nakagomi M, Yamagata N, Katsuki H, Kawahara K, Kitaoka K, et al. Tamibarotene: a candidate retinoid drug for Alzheimer's disease. Biol Pharm Bull. 2012;35:1206-12 pubmed

Matsushita H, Hijioka M, Hisatsune A, Isohama Y, Shudo K, Katsuki H. Natural and synthetic retinoids afford therapeutic effects on intracerebral hemorrhage in mice. Eur J Pharmacol. 2012;683:125-31 pubmed publisher

Inoue A, Kawakami C, Takitani K, Tamai H. Sustained molecular remission after arsenic trioxide and gemutuzumab ozogamicin in a pediatric patient with relapsed acute promyelocytic leukemia. Pediatr Hematol Oncol. 2012;29:170-2 pubmed publisher

Nishimori H, Maeda Y, Teshima T, Sugiyama H, Kobayashi K, Yamasuji Y, et al. Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17. Blood. 2012;119:285-95 pubmed publisher

Ye H, Qiu B, Lin Z, Chen G. Fluorescence spectrometric study on the interaction of tamibarotene with bovine serum albumin. Luminescence. 2011;26:336-41 pubmed publisher

Bian H, Feng J, Li M, Xu W. Novel antileukemic agents derived from tamibarotene and nitric oxide donors. Bioorg Med Chem Lett. 2011;21:7025-9 pubmed publisher

Yuan C, Zhang Y, Cheng Y, Xue X, Xu W, Qu X. A112, a tamibarotene dimethylaminoethyl ester, may inhibit human leukemia cell growth more potently than tamibarotene. Leuk Lymphoma. 2012;53:295-304 pubmed publisher

Ohata K, Yamazaki H, Asakura H, Shimadoi S, Nakao S. Tamibarotene-induced low-grade reversible intravascular coagulation in a patient with acute promyelocytic leukemia. Thromb Res. 2012;129:213-4 pubmed publisher

Malavasi F. Editorial: CD38 and retinoids: a step toward a cure. J Leukoc Biol. 2011;90:217-9 pubmed publisher

Maeda Y, Kawauchi M, Miyatake J, Hirase C, Yamaguchi T, Matsumura I. Effects of tamibarotene for the treatment of adult T cell leukemia. Ann Hematol. 2012;91:629-31 pubmed publisher

Morohoshi K, Yoshida K, Nakagawa Y, Hoshikawa S, Ozaki H, Takahashi Y, et al. Effects of synthetic retinoid Am80 on iodide-induced autoimmune thyroiditis in nonobese diabetic mice. Cell Immunol. 2011;270:1-4 pubmed publisher

Naina H, Levitt D, Vusirikala M, Anderson L, Scaglioni P, Kirk A, et al. Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene. J Clin Oncol. 2011;29:e534-6 pubmed publisher

Uruno A, Noguchi N, Matsuda K, Nata K, Yoshikawa T, Chikamatsu Y, et al. All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible involvement of protein kinase C-delta. J Leukoc Biol. 2011;90:235-47 pubmed publisher

Keino H, Watanabe T, Sato Y, Okada A. Oral administration of retinoic acid receptor-alpha/beta-specific ligand Am80 suppresses experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci. 2011;52:1548-56 pubmed publisher

Shiohira H, Kitaoka A, Shirasawa H, Enjoji M, Nakashima M. Am80 induces neuronal differentiation in a human neuroblastoma NH-12 cell line. Int J Mol Med. 2010;26:393-9 pubmed

Yokosawa M, Sonoda Y, Sugiyama S, Saito R, Yamashita Y, Nishihara M, et al. Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts. Tohoku J Exp Med. 2010;221:257-64 pubmed

Di Veroli A, Ramadan S, Divona M, Cudillo L, Giannì L, Wieland S, et al. Molecular remission in advanced acute promyelocytic leukaemia after treatment with the oral synthetic retinoid Tamibarotene. Br J Haematol. 2010;151:99-101 pubmed publisher

Matsushita H, Hijioka M, Hisatsune A, Isohama Y, Shudo K, Katsuki H. A retinoic acid receptor agonist Am80 rescues neurons, attenuates inflammatory reactions, and improves behavioral recovery after intracerebral hemorrhage in mice. J Cereb Blood Flow Metab. 2011;31:222-34 pubmed publisher

Miwako I, Kagechika H. Tamibarotene. Drugs Today (Barc). 2007;43:563-8 pubmed

Takeuchi M. [Clinical experience with a new synthetic retinoid, tamibarotene (Am-80) for relapsed or refractory acute promyelocytic leukemia]. Gan To Kagaku Ryoho. 2006;33:397-401 pubmed

. Tamibarotene: AM 80, retinobenzoic acid, Tamibaro. Drugs R D. 2004;5:359-62 pubmed