This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Trifluorothymidine
catalog :
T2255
citations: 7
Reference
Lynch C, Zhao J, Huang R, Xiao J, Li L, Heyward S, et al. Quantitative high-throughput identification of drugs as modulators of human constitutive androstane receptor. Sci Rep. 2015;5:10405 pubmed publisher
Lin H, Guo X, Zhang S, Dial S, Guo L, Manjanatha M, et al. Mechanistic evaluation of Ginkgo biloba leaf extract-induced genotoxicity in L5178Y cells. Toxicol Sci. 2014;139:338-49 pubmed publisher
Suzuki N, Emura T, Fukushima M. Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes. Int J Oncol. 2011;39:263-70 pubmed publisher
Suzuki N, Fukushima M. Simple and rapid enzymatic method for the synthesis of single-strand oligonucleotides containing trifluorothymidine. Nucleosides Nucleotides Nucleic Acids. 2010;29:896-904 pubmed publisher
Temmink O, Bijnsdorp I, Prins H, Losekoot N, Adema A, Smid K, et al. Trifluorothymidine resistance is associated with decreased thymidine kinase and equilibrative nucleoside transporter expression or increased secretory phospholipase A2. Mol Cancer Ther. 2010;9:1047-57 pubmed publisher
Bijnsdorp I, Peters G, Temmink O, Fukushima M, Kruyt F. Differential activation of cell death and autophagy results in an increased cytotoxic potential for trifluorothymidine compared to 5-fluorouracil in colon cancer cells. Int J Cancer. 2010;126:2457-68 pubmed publisher
Bijnsdorp I, Kruyt F, Fukushima M, Peters G. Trifluorothymidine induces cell death independently of p53. Nucleosides Nucleotides Nucleic Acids. 2008;27:699-703 pubmed publisher
product information
Catalog Number :
T2255
Product Name :
Trifluorothymidine
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥99% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA