product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-TDP-43 (C-terminal) antibody produced in rabbit
catalog :
T1580
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s5c
  • western blot; mouse; 1:5000; loading ...; fig 3a
Becker L, Huang B, Bieri G, Ma R, Knowles D, Jafar Nejad P, et al. Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice. Nature. 2017;544:367-371 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:50; fig 7
  • western blot; human; fig 3
  • immunocytochemistry; mouse; 1:50; fig 2
Lin P, Folorunso O, Taglialatela G, Pierce A. Overexpression of heat shock factor 1 maintains TAR DNA binding protein 43 solubility via induction of inducible heat shock protein 70 in cultured cells. J Neurosci Res. 2016;94:671-82 pubmed publisher
Katsumata Y, Fardo D, Kukull W, Nelson P. Dichotomous scoring of TDP-43 proteinopathy from specific brain regions in 27 academic research centers: associations with Alzheimer's disease and cerebrovascular disease pathologies. Acta Neuropathol Commun. 2018;6:142 pubmed publisher
product information
Product No. :
T1580
Product Name :
Anti-TDP-43 (C-terminal) antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for immunohistochemistry: 5-10 μg/mL using rat, mouse, and human kidney; western blot: 1-2 μg/mL using human U2OS cell lysates; indirect immunofluorescence: 5-10 μg/mL using human HepG2 cells
Species Reactivity :
rat, human, mouse
Concentration :
~1.0 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA