This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Thioredoxin from Escherichia coli
catalog :
T0910
citations: 83
Reference
Tailor V, Ballal A. Novel molecular insights into the function and the antioxidative stress response of a Peroxiredoxin Q protein from cyanobacteria. Free Radic Biol Med. 2017;106:278-287 pubmed publisher
Wang D, Wang Y, Wan X, Yang C, Zhang J. Green tea polyphenol (-)-epigallocatechin-3-gallate triggered hepatotoxicity in mice: responses of major antioxidant enzymes and the Nrf2 rescue pathway. Toxicol Appl Pharmacol. 2015;283:65-74 pubmed publisher
Wei M, Xing K, Fan Y, Libondi T, Lou M. Loss of thiol repair systems in human cataractous lenses. Invest Ophthalmol Vis Sci. 2014;56:598-605 pubmed publisher
Xing S, Zhang C, Yuan J, Yang H, Zhao S, Zhang H. Adiponectin induces apoptosis in hepatocellular carcinoma through differential modulation of thioredoxin proteins. Biochem Pharmacol. 2015;93:221-31 pubmed publisher
Kim G, Lee Y, Lee G, Cho Y, Lee Y, Jang Y, et al. Overexpression of malic enzyme in the larval stage extends Drosophila lifespan. Biochem Biophys Res Commun. 2015;456:676-82 pubmed publisher
Peng M, Cascio D, Egea P. Crystal structure and solution characterization of the thioredoxin-2 from Plasmodium falciparum, a constituent of an essential parasitic protein export complex. Biochem Biophys Res Commun. 2015;456:403-9 pubmed publisher
González Chávez Z, Olin Sandoval V, Rodíguez Zavala J, Moreno Sánchez R, Saavedra E. Metabolic control analysis of the Trypanosoma cruzi peroxide detoxification pathway identifies tryparedoxin as a suitable drug target. Biochim Biophys Acta. 2015;1850:263-73 pubmed publisher
Zhang S, An S, Li Z, Wu F, Yang Q, Liu Y, et al. Identification and validation of reference genes for normalization of gene expression analysis using qRT-PCR in Helicoverpa armigera (Lepidoptera: Noctuidae). Gene. 2015;555:393-402 pubmed publisher
Kasuno K, Shirakawa K, Yoshida H, Mori K, Kimura H, Takahashi N, et al. Renal redox dysregulation in AKI: application for oxidative stress marker of AKI. Am J Physiol Renal Physiol. 2014;307:F1342-51 pubmed publisher
Kaadige M, Yang J, Wilde B, Ayer D. MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction. Mol Cell Biol. 2015;35:101-10 pubmed publisher
Ebrecht A, Asención Diez M, Piattoni C, Guerrero S, Iglesias A. The UDP-glucose pyrophosphorylase from Giardia lamblia is redox regulated and exhibits promiscuity to use galactose-1-phosphate. Biochim Biophys Acta. 2015;1850:88-96 pubmed publisher
Björnberg O, Efler P, Ebong E, Svensson B, Hägglund P. Lactococcus lactis TrxD represents a subgroup of thioredoxins prevalent in Gram-positive bacteria containing WCXDC active site motifs. Arch Biochem Biophys. 2014;564:164-72 pubmed publisher
Viefhues A, Heller J, Temme N, Tudzynski P. Redox systems in Botrytis cinerea: impact on development and virulence. Mol Plant Microbe Interact. 2014;27:858-74 pubmed publisher
Li C, Wang L, Zhang J, Huang M, Wong F, Liu X, et al. CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis. Biochim Biophys Acta. 2014;1842:1121-9 pubmed publisher
Feuer S, Liu X, Donjacour A, Lin W, Simbulan R, Giritharan G, et al. Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis. Endocrinology. 2014;155:1956-69 pubmed publisher
Machov I, Sna el J, Zimmermann M, Laubitz D, Plocinski P, Oehlmann W, et al. Mycobacterium tuberculosis phosphoenolpyruvate carboxykinase is regulated by redox mechanisms and interaction with thioredoxin. J Biol Chem. 2014;289:13066-78 pubmed publisher
Kriznik A, Boschi Muller S, Branlant G. Kinetic evidence that methionine sulfoxide reductase A can reveal its oxidase activity in the presence of thioredoxin. Arch Biochem Biophys. 2014;548:54-9 pubmed publisher
Muchowicz A, Firczuk M, Chlebowska J, Nowis D, Stachura J, Barankiewicz J, et al. Adenanthin targets proteins involved in the regulation of disulphide bonds. Biochem Pharmacol. 2014;89:210-6 pubmed publisher
Jing G, Westwell Roper C, Chen J, Xu G, Verchere C, Shalev A. Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2. J Biol Chem. 2014;289:11807-15 pubmed publisher
Sun K, Eriksson S, Tan Y, Zhang L, Arner E, Zhang J. Serum thioredoxin reductase levels increase in response to chemically induced acute liver injury. Biochim Biophys Acta. 2014;1840:2105-11 pubmed publisher
Sangpairoj K, Changklungmoa N, Vanichviriyakit R, Sobhon P, Chaithirayanon K. Analysis of the expression and antioxidant activity of 2-Cys peroxiredoxin protein in Fasciola gigantica. Exp Parasitol. 2014;140:24-32 pubmed publisher
Cerutti N, Killick M, Jugnarain V, Papathanasopoulos M, Capovilla A. Disulfide reduction in CD4 domain 1 or 2 is essential for interaction with HIV glycoprotein 120 (gp120), which impairs thioredoxin-driven CD4 dimerization. J Biol Chem. 2014;289:10455-65 pubmed publisher
Kim H, Koedrith P, Lee S, Kim Y, Seo Y. Base excision DNA repair defect in thioredoxin-1 (Trx1)-deficient cells. Mutat Res. 2013;751-752:1-7 pubmed
Sadowska Bartosz I, Adamczyk Sowa M, Gajewska A, Bartosz G. Oxidative modification of blood serum proteins in multiple sclerosis after interferon or mitoxantrone treatment. J Neuroimmunol. 2014;266:67-74 pubmed publisher
Randall M, Hristova M, van Der Vliet A. Protein alkylation by the α,β-unsaturated aldehyde acrolein. A reversible mechanism of electrophile signaling?. FEBS Lett. 2013;587:3808-14 pubmed publisher
Joshi R, Kumar A, Manral S, Sinha R, Arora S, Sharma A, et al. Calreticulin transacetylase mediated upregulation of thioredoxin by 7,8-diacetoxy-4-methylcoumarin enhances the antioxidant potential and the expression of vascular endothelial growth factor in peripheral blood mononuclear cells. Chem Biol Interact. 2013;206:327-36 pubmed publisher
Née G, Aumont Nicaise M, Zaffagnini M, Nessler S, Valerio Lepiniec M, Issakidis Bourguet E. Redox regulation of chloroplastic G6PDH activity by thioredoxin occurs through structural changes modifying substrate accessibility and cofactor binding. Biochem J. 2014;457:117-25 pubmed publisher
Du Y, Zhang H, Zhang X, Lu J, Holmgren A. Thioredoxin 1 is inactivated due to oxidation induced by peroxiredoxin under oxidative stress and reactivated by the glutaredoxin system. J Biol Chem. 2013;288:32241-7 pubmed publisher
Hawkes H, Karlenius T, Tonissen K. Regulation of the human thioredoxin gene promoter and its key substrates: a study of functional and putative regulatory elements. Biochim Biophys Acta. 2014;1840:303-14 pubmed publisher
An N, Janech M, Bland A, Lazarchick J, Arthur J, Kang Y. Proteomic analysis of murine bone marrow niche microenvironment identifies thioredoxin as a novel agent for radioprotection and for enhancing donor cell reconstitution. Exp Hematol. 2013;41:944-56 pubmed publisher
Xu G, Chen J, Jing G, Shalev A. Thioredoxin-interacting protein regulates insulin transcription through microRNA-204. Nat Med. 2013;19:1141-6 pubmed publisher
Zhu Z, Yang G, Wang Y, Yang J, Gao A, Niu P, et al. Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in rats. Toxicol Lett. 2013;222:289-94 pubmed publisher
Parsons Z, Gates K. Thiol-dependent recovery of catalytic activity from oxidized protein tyrosine phosphatases. Biochemistry. 2013;52:6412-23 pubmed publisher
Zhou S, Narukami T, Masuo S, Shimizu M, Fujita T, Doi Y, et al. NO-inducible nitrosothionein mediates NO removal in tandem with thioredoxin. Nat Chem Biol. 2013;9:657-63 pubmed publisher
Fushimi F, Taguchi K, Izumi H, Kohno K, Kuwano M, Ono M, et al. Peroxiredoxins, thioredoxin, and Y-box-binding protein-1 are involved in the pathogenesis and progression of dialysis-associated renal cell carcinoma. Virchows Arch. 2013;463:553-62 pubmed publisher
Go Y, Jones D. The redox proteome. J Biol Chem. 2013;288:26512-20 pubmed publisher
Stangherlin A, Reddy A. Regulation of circadian clocks by redox homeostasis. J Biol Chem. 2013;288:26505-11 pubmed publisher
Fritz Wolf K, Jortzik E, Stumpf M, Preuss J, Iozef R, Rahlfs S, et al. Crystal structure of the Plasmodium falciparum thioredoxin reductase-thioredoxin complex. J Mol Biol. 2013;425:3446-60 pubmed publisher
Brooks M, Sylak Glassman E, Fleming G, Niyogi K. A thioredoxin-like/?-propeller protein maintains the efficiency of light harvesting in Arabidopsis. Proc Natl Acad Sci U S A. 2013;110:E2733-40 pubmed publisher
Lee J, Shin J, Hwang S, Gwag B, McKee A, Lee J, et al. MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS. Proc Natl Acad Sci U S A. 2013;110:12066-71 pubmed publisher
Chen B, Nelin V, Locy M, Jin Y, Tipple T. Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol. 2013;305:L389-95 pubmed publisher
Del Giudice I, Limauro D, Pedone E, Bartolucci S, Fiorentino G. A novel arsenate reductase from the bacterium Thermus thermophilus HB27: its role in arsenic detoxification. Biochim Biophys Acta. 2013;1834:2071-9 pubmed publisher
Manoharan R, Seong H, Ha H. Thioredoxin inhibits MPK38-induced ASK1, TGF-?, and p53 function in a phosphorylation-dependent manner. Free Radic Biol Med. 2013;63:313-24 pubmed publisher
Yao P, Hao L, Wang F, Chen X, Yan Y, Guo X, et al. Molecular cloning, expression and antioxidant characterisation of a typical thioredoxin gene (AccTrx2) in Apis cerana cerana. Gene. 2013;527:33-41 pubmed publisher
Iverson S, Eriksson S, Xu J, Prigge J, Talago E, Meade T, et al. A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification. Free Radic Biol Med. 2013;63:369-80 pubmed publisher
Liu J, Mu C, Yue W, Li J, Ma B, Zhao L, et al. A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis. Free Radic Biol Med. 2013;63:485-94 pubmed publisher
Hemmis C, Schildbach J. Thioredoxin-like proteins in F and other plasmid systems. Plasmid. 2013;70:168-89 pubmed publisher
Simonetti F, Teppa E, Chernomoretz A, Nielsen M, Marino Buslje C. MISTIC: Mutual information server to infer coevolution. Nucleic Acids Res. 2013;41:W8-14 pubmed publisher
Zervou S, Ray T, Sahgal N, Sebag Montefiore L, Cross R, Medway D, et al. A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis. Am J Physiol Endocrinol Metab. 2013;305:E263-70 pubmed publisher
Yadav P, Yamada K, Chiku T, Koutmos M, Banerjee R. Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase. J Biol Chem. 2013;288:20002-13 pubmed publisher
Ebling F, Samms R. Txnip, tanycytes, and torpor. Endocrinology. 2013;154:1970-2 pubmed publisher
Hartmann S, Tousseyn T, Döring C, Flüchter P, Hackstein H, Herreman A, et al. Macrophages in T cell/histiocyte rich large B cell lymphoma strongly express metal-binding proteins and show a bi-activated phenotype. Int J Cancer. 2013;133:2609-18 pubmed publisher
Phulera S, Mande S. The crystal structure of Mycobacterium tuberculosis NrdH at 0.87 Å suggests a possible mode of its activity. Biochemistry. 2013;52:4056-65 pubmed publisher
Arias D, Marquez V, Chiribao M, Gadelha F, Robello C, Iglesias A, et al. Redox metabolism in Trypanosoma cruzi: functional characterization of tryparedoxins revisited. Free Radic Biol Med. 2013;63:65-77 pubmed publisher
Han K, Ayer D. MondoA senses adenine nucleotides: transcriptional induction of thioredoxin-interacting protein. Biochem J. 2013;453:209-18 pubmed publisher
Tobe R, Naranjo Suarez S, Everley R, Carlson B, Turanov A, Tsuji P, et al. High error rates in selenocysteine insertion in mammalian cells treated with the antibiotic doxycycline, chloramphenicol, or geneticin. J Biol Chem. 2013;288:14709-15 pubmed publisher
Hand L, Saer B, Hui S, Jinnah H, Steinlechner S, Loudon A, et al. Induction of the metabolic regulator Txnip in fasting-induced and natural torpor. Endocrinology. 2013;154:2081-91 pubmed publisher
Xue X, Yan Z, Li W, Li M, Qin X, Zhang C, et al. Construction, expression, and characterization of thymosin alpha 1 tandem repeats in Escherichia coli. Biomed Res Int. 2013;2013:720285 pubmed publisher
Lenart A, Pawłowski K. Intersection of selenoproteins and kinase signalling. Biochim Biophys Acta. 2013;1834:1279-84 pubmed publisher
Kanari Y, Sato Y, Aoyama S, Muta T. Thioredoxin-interacting protein gene expression via MondoA is rapidly and transiently suppressed during inflammatory responses. PLoS ONE. 2013;8:e59026 pubmed publisher
Polekhina G, Ascher D, Kok S, Beckham S, Wilce M, Waltham M. Structure of the N-terminal domain of human thioredoxin-interacting protein. Acta Crystallogr D Biol Crystallogr. 2013;69:333-44 pubmed publisher
Zheng M, Li X, Tang K, Sharma N, Wyatt T, Patel K, et al. Pyruvate restores β-adrenergic sensitivity of L-type Ca(2+) channels in failing rat heart: role of protein phosphatase. Am J Physiol Heart Circ Physiol. 2013;304:H1352-60 pubmed publisher
Sugano E, Isago H, Murayama N, Tamai M, Tomita H. Different anti-oxidant effects of thioredoxin 1 and thioredoxin 2 in retinal epithelial cells. Cell Struct Funct. 2013;38:81-8 pubmed
Penney R, Roy D. Thioredoxin-mediated redox regulation of resistance to endocrine therapy in breast cancer. Biochim Biophys Acta. 2013;1836:60-79 pubmed publisher
Wong R, Hagen T. Mechanistic target of rapamycin (mTOR) dependent regulation of thioredoxin interacting protein (TXNIP) transcription in hypoxia. Biochem Biophys Res Commun. 2013;433:40-6 pubmed publisher
Kembro J, Aon M, Winslow R, O ROURKE B, Cortassa S. Integrating mitochondrial energetics, redox and ROS metabolic networks: a two-compartment model. Biophys J. 2013;104:332-43 pubmed publisher
Tanaka R, Watanabe H, Kodama A, Chuang V, Ishima Y, Hamasaki K, et al. Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression. J Pharmacol Exp Ther. 2013;345:271-83 pubmed publisher
Zhou F, Liu P, Ying G, Zhu X, Shen H, Chen G. Effects of thioredoxin-1 on neurogenesis after brain ischemia/reperfusion injury. CNS Neurosci Ther. 2013;19:204-5 pubmed publisher
Szoszkiewicz R. Single-molecule studies of disulfide bond reduction pathways used by human thioredoxin. Biophys Chem. 2013;173-174:31-8 pubmed publisher
Mohd Yusuf S, Bailey U, Tan N, Jamaluddin M, Schulz B. Mixed disulfide formation in vitro between a glycoprotein substrate and yeast oligosaccharyltransferase subunits Ost3p and Ost6p. Biochem Biophys Res Commun. 2013;432:438-43 pubmed publisher
Oku M, Hoseki J, Ichiki Y, Sakai Y. A fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae. FEBS Lett. 2013;587:793-8 pubmed publisher
Naticchia M, Brown H, Garcia F, Lamade A, Justice S, Herrin R, et al. Bifunctional electrophiles cross-link thioredoxins with redox relay partners in cells. Chem Res Toxicol. 2013;26:490-7 pubmed publisher
Ashino T, Yamamoto M, Yoshida T, Numazawa S. Redox-sensitive transcription factor Nrf2 regulates vascular smooth muscle cell migration and neointimal hyperplasia. Arterioscler Thromb Vasc Biol. 2013;33:760-8 pubmed publisher
Zhou C, Bian M, Liao H, Mao Q, Li R, Zhou J, et al. Identification and immunological characterization of thioredoxin transmembrane-related protein from Clonorchis sinensis. Parasitol Res. 2013;112:1729-36 pubmed publisher
Schlosser S, Leitsch D, Duch ne M. Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example. Biochem J. 2013;451:277-88 pubmed publisher
Turturice B, Lamm M, Tasch J, Zalewski A, Kooistra R, Schroeter E, et al. Expression of cytosolic peroxiredoxins in Plasmodium berghei ookinetes is regulated by environmental factors in the mosquito bloodmeal. PLoS Pathog. 2013;9:e1003136 pubmed publisher
Lanotte P, Perivier M, Haguenoer E, Mereghetti L, Burucoa C, Claverol S, et al. Proteomic biomarkers associated with Streptococcus agalactiae invasive genogroups. PLoS ONE. 2013;8:e54393 pubmed publisher
Van Laer K, Dziewulska A, Fislage M, Wahni K, Hbeddou A, Collet J, et al. NrdH-redoxin of Mycobacterium tuberculosis and Corynebacterium glutamicum dimerizes at high protein concentration and exclusively receives electrons from thioredoxin reductase. J Biol Chem. 2013;288:7942-55 pubmed publisher
Ishii T, Funato Y, Miki H. Thioredoxin-related protein 32 (TRP32) specifically reduces oxidized phosphatase of regenerating liver (PRL). J Biol Chem. 2013;288:7263-70 pubmed publisher
Permpoonpattana P, Phetcharaburanin J, Mikelsone A, Dembek M, Tan S, Brisson M, et al. Functional characterization of Clostridium difficile spore coat proteins. J Bacteriol. 2013;195:1492-503 pubmed publisher
Wu C, Hwang C, Yang D. Protective effects of brain-derived neurotrophic factor against neurotoxicity of 3-nitropropionic acid in rat cortical neurons. Neurotoxicology. 2009;30:718-26 pubmed publisher
M ller M, Hederstedt L. Extracytoplasmic processes impaired by inactivation of trxA (thioredoxin gene) in Bacillus subtilis. J Bacteriol. 2008;190:4660-5 pubmed publisher
May J, Qu Z, Nelson D. Uptake and reduction of alpha-lipoic acid by human erythrocytes. Clin Biochem. 2007;40:1135-42 pubmed
product information
Catalog Number :
T0910
Product Name :
Thioredoxin from Escherichia coli
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
recombinant, expressed in E. coli, essentially salt-free, lyophilized powder, ?3 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA