This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
TNF-α human
catalog :
SRP3177
citations: 142
Reference
Snider E, Crowley A, Raykin J, Kim R, Splaine F, Ethier C. A flexible, robust microbead-based assay for quantification and normalization of target protein concentrations. Anal Biochem. 2020;590:113510 pubmed publisher
Roca F, Whitworth L, Redmond S, Jones A, Ramakrishnan L. TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit. Cell. 2019;178:1344-1361.e11 pubmed publisher
Shen L, Xiao Y, Wu Q, Liu L, Zhang C, Pan X. TLR4/NF-κB axis signaling pathway-dependent up-regulation of miR-625-5p contributes to human intervertebral disc degeneration by targeting COL1A1. Am J Transl Res. 2019;11:1374-1388 pubmed
Chen Z, Han Y, Deng C, Chen W, Jin L, Chen H, et al. Inflammation-dependent downregulation of miR-194-5p contributes to human intervertebral disc degeneration by targeting CUL4A and CUL4B. J Cell Physiol. 2019;: pubmed publisher
Miyagi M, Uchida K, Takano S, Fujimaki H, Aikawa J, Sekiguchi H, et al. Macrophage-derived inflammatory cytokines regulate growth factors and pain-related molecules in mice with intervertebral disc injury. J Orthop Res. 2018;: pubmed publisher
Gallelli L, Falcone D, Cannataro R, Perri M, Serra R, Pelaia G, et al. Theophylline action on primary human bronchial epithelial cells under proinflammatory stimuli and steroidal drugs: a therapeutic rationale approach. Drug Des Devel Ther. 2017;11:265-272 pubmed publisher
Sun Q, Zhang W, Zhong W, Sun X, Zhou Z. Pharmacological inhibition of NOX4 ameliorates alcohol-induced liver injury in mice through improving oxidative stress and mitochondrial function. Biochim Biophys Acta Gen Subj. 2017;1861:2912-2921 pubmed publisher
Schotte H, Schmidt H, Gaubitz M, Drynda S, Kekow J, Willeke P, et al. Interleukin-6 promoter haplotypes are associated with etanercept response in patients with rheumatoid arthritis. Clin Rheumatol. 2015;34:2021-8 pubmed publisher
Shi X, Zhou Z, Wang L, Wang M, Shi S, Wang Z, et al. The immunomodulation of nicotinic acetylcholine receptor subunits in Zhikong scallop Chlamys farreri. Fish Shellfish Immunol. 2015;47:611-22 pubmed publisher
Yang P, Chiang T, Hsieh C, Huang Y, Wong L, Hung M, et al. The effect of ephrin-A1 on resistance to Photofrin-mediated photodynamic therapy in esophageal squamous cell carcinoma cells. Lasers Med Sci. 2015;30:2353-61 pubmed publisher
Ohana O, Ozer J, Prinsloo I, Benharroch D, Gopas J. Hodgkin lymphoma cell lines bind to platelets. Incubation with platelets induces CD15 and P-selectin dependent adhesion of the cell lines to Human Umbilical Vein Endothelial cells (HUVEC). Cancer Biol Ther. 2015;16:1651-9 pubmed publisher
Goodall L, Ovecka M, Rycroft D, Friel S, Sanderson A, Mistry P, et al. Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension. PLoS ONE. 2015;10:e0137065 pubmed publisher
Cataldi M, Shah N, Felt S, Grdzelishvili V. Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1. Virology. 2015;485:340-54 pubmed publisher
Duffau P, Menn Josephy H, Cuda C, Dominguez S, Aprahamian T, Watkins A, et al. Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model. Arthritis Rheumatol. 2015;67:3146-57 pubmed publisher
Ding B, Parmigiani A, Yang C, Budanov A. Sestrin2 facilitates death receptor-induced apoptosis in lung adenocarcinoma cells through regulation of XIAP degradation. Cell Cycle. 2015;14:3231-41 pubmed publisher
Wilhelmsen K, Xu F, Farrar K, Tran A, Khakpour S, Sundar S, et al. Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation. Sci Signal. 2015;8:ra86 pubmed publisher
Barone F, Nayar S, Campos J, Cloake T, Withers D, Toellner K, et al. IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs. Proc Natl Acad Sci U S A. 2015;112:11024-9 pubmed publisher
Hayashi T, Horiuchi A, Sano K, Yaegashi N, Konishi I. Uterine Leiomyosarcoma Tumorigenesis in Lmp2-deficient Mice: Involvement of Impaired Anti-oncogenic Factor IRF1. Anticancer Res. 2015;35:4665-79 pubmed
Mahata B, Biswas S, Rayman P, Chahlavi A, Ko J, Bhattacharjee A, et al. GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway. PLoS ONE. 2015;10:e0134425 pubmed publisher
Peters E, Geraci S, Heemskerk S, Wilmer M, Bilos A, Kraenzlin B, et al. Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate. Br J Pharmacol. 2015;172:4932-45 pubmed publisher
Tian E, Børset M, Sawyer J, Brede G, Våtsveen T, Hov H, et al. Allelic mutations in noncoding genomic sequences construct novel transcription factor binding sites that promote gene overexpression. Genes Chromosomes Cancer. 2015;54:692-701 pubmed publisher
Hirano T, Murakami T, Ono H, Sakurai A, Tominaga T, Takahashi T, et al. A Novel Interaction between FLICE-Associated Huge Protein (FLASH) and E2A Regulates Cell Proliferation and Cellular Senescence via Tumor Necrosis Factor (TNF)-Alpha-p21WAF1/CIP1 Axis. PLoS ONE. 2015;10:e0133205 pubmed publisher
Alaaeddine N, Antoniou J, Moussa M, Hilal G, Kreichaty G, Ghanem I, et al. The chemokine CCL20 induces proinflammatory and matrix degradative responses in cartilage. Inflamm Res. 2015;64:721-31 pubmed publisher
Croes M, Oner F, Kruyt M, Blokhuis T, Bastian O, Dhert W, et al. Proinflammatory Mediators Enhance the Osteogenesis of Human Mesenchymal Stem Cells after Lineage Commitment. PLoS ONE. 2015;10:e0132781 pubmed publisher
Zhou Y, Yamada N, Tanaka T, Hori T, Yokoyama S, Hayakawa Y, et al. Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2. Nat Commun. 2015;6:7679 pubmed publisher
Panicker N, Saminathan H, Jin H, Neal M, Harischandra D, Gordon R, et al. Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease. J Neurosci. 2015;35:10058-77 pubmed publisher
Rom S, Dykstra H, Zuluaga Ramirez V, Reichenbach N, Persidsky Y. miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions. J Cereb Blood Flow Metab. 2015;35:1957-65 pubmed publisher
He D, Kou X, Yang R, Liu D, Wang X, Luo Q, et al. M1-like Macrophage Polarization Promotes Orthodontic Tooth Movement. J Dent Res. 2015;94:1286-94 pubmed publisher
Hiyama A, Yokoyama K, Nukaga T, Sakai D, Mochida J. Response to tumor necrosis factor-α mediated inflammation involving activation of prostaglandin E2 and Wnt signaling in nucleus pulposus cells. J Orthop Res. 2015;33:1756-68 pubmed publisher
Jeon Y, Kee J, Kim D, Han Y, Kim S, Kim S, et al. Effects of Ixeris dentata water extract and caffeic acid on allergic inflammation in vivo and in vitro. BMC Complement Altern Med. 2015;15:196 pubmed publisher
Watson R, Buck J, Levin L, Winger R, Wang J, Arase H, et al. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration. J Exp Med. 2015;212:1021-41 pubmed publisher
Manček Keber M, Frank Bertoncelj M, Hafner Bratkovič I, Smole A, Zorko M, Pirher N, et al. Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesicles. Sci Signal. 2015;8:ra60 pubmed publisher
Xue Q, Lu Y, Eisele M, Sulistijo E, Khan N, Fan R, et al. Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation. Sci Signal. 2015;8:ra59 pubmed publisher
Zhao J, Zhao D, Poage G, Mazumdar A, Zhang Y, Hill J, et al. Death-associated protein kinase 1 promotes growth of p53-mutant cancers. J Clin Invest. 2015;125:2707-20 pubmed publisher
Ocvirk S, Sava I, Lengfelder I, Lagkouvardos I, Steck N, Roh J, et al. Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels. PLoS Pathog. 2015;11:e1004911 pubmed publisher
Boosani C, Dhar K, Agrawal D. Down-regulation of hsa-miR-1264 contributes to DNMT1-mediated silencing of SOCS3. Mol Biol Rep. 2015;42:1365-76 pubmed publisher
Liu C, Mei W, Tang J, Yuan Q, Huang L, Lu M, et al. Mefunidone attenuates tubulointerstitial fibrosis in a rat model of unilateral ureteral obstruction. PLoS ONE. 2015;10:e0129283 pubmed publisher
Brito H, Martins A, Lavrado J, Mendes E, Francisco A, Santos S, et al. Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives. PLoS ONE. 2015;10:e0126891 pubmed publisher
Fraser R, Whitley G, Thilaganathan B, Cartwright J. Decidual natural killer cells regulate vessel stability: implications for impaired spiral artery remodelling. J Reprod Immunol. 2015;110:54-60 pubmed publisher
Fauster A, Rebsamen M, Huber K, Bigenzahn J, Stukalov A, Lardeau C, et al. A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis. Cell Death Dis. 2015;6:e1767 pubmed publisher
Wu Z, Huang X, Burton A, Swift K. Glycoprotein labeling with click chemistry (GLCC) and carbohydrate detection. Carbohydr Res. 2015;412:1-6 pubmed publisher
Swamy M, Abeler Dörner L, Chettle J, Mahlakõiv T, Goubau D, Chakravarty P, et al. Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance. Nat Commun. 2015;6:7090 pubmed publisher
Marshall D, Lyman S, McCauley S, Kovalenko M, Spangler R, Liu C, et al. Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer. PLoS ONE. 2015;10:e0127063 pubmed publisher
Maiuri A, Breier A, Gora L, Parkins R, Ganey P, Roth R. Cytotoxic Synergy Between Cytokines and NSAIDs Associated With Idiosyncratic Hepatotoxicity Is Driven by Mitogen-Activated Protein Kinases. Toxicol Sci. 2015;146:265-80 pubmed publisher
Piotrowska Tomala K, Bah M, Jankowska K, Lukasik K, Warmowski P, Galvão A, et al. Lipopolysaccharides, cytokines, and nitric oxide affect secretion of prostaglandins and leukotrienes by bovine mammary gland during experimentally induced mastitis in vivo and in vitro. Domest Anim Endocrinol. 2015;52:90-9 pubmed publisher
Agca C, Boldt K, Gubler A, Meneau I, Corpet A, Samardzija M, et al. Expression of leukemia inhibitory factor in Müller glia cells is regulated by a redox-dependent mRNA stability mechanism. BMC Biol. 2015;13:30 pubmed publisher
Li L, Ryoo J, Lee K, Choi B, Baek K. Genetic variation in the Mcp-1 gene promoter associated with the risk of polycystic ovary syndrome. PLoS ONE. 2015;10:e0123045 pubmed publisher
Dong C, He M, Tu W, Konishi T, Liu W, Xie Y, et al. The differential role of human macrophage in triggering secondary bystander effects after either gamma-ray or carbon beam irradiation. Cancer Lett. 2015;363:92-100 pubmed publisher
Walter B, Purmessur D, Likhitpanichkul M, Weinberg A, Cho S, Qureshi S, et al. Inflammatory Kinetics and Efficacy of Anti-inflammatory Treatments on Human Nucleus Pulposus Cells. Spine (Phila Pa 1976). 2015;40:955-63 pubmed publisher
Mamat U, Wilke K, Bramhill D, Schromm A, Lindner B, Kohl T, et al. Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins. Microb Cell Fact. 2015;14:57 pubmed publisher
Cristofanon S, Abhari B, Krueger M, Tchoghandjian A, Momma S, Calaminus C, et al. Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis. Cell Death Dis. 2015;6:e1724 pubmed publisher
Seu L, Sabbaj S, Duverger A, Wagner F, Anderson J, Davies E, et al. Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection. J Virol. 2015;89:6656-72 pubmed publisher
Jungck D, Knobloch J, Körber S, Lin Y, Konradi J, Yanik S, et al. Endothelin receptor B protects granulocyte macrophage colony-stimulating factor mRNA from degradation. J Pharmacol Exp Ther. 2015;353:564-72 pubmed publisher
Yano C, Saeki H, Komine M, Kagami S, Tsunemi Y, Ohtsuki M, et al. Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes. Ann Dermatol. 2015;27:152-6 pubmed publisher
Ng C, Fong L, Sulaiman M, Moklas M, Yong Y, Hakim M, et al. Interferon-Gamma Increases Endothelial Permeability by Causing Activation of p38 MAP Kinase and Actin Cytoskeleton Alteration. J Interferon Cytokine Res. 2015;35:513-22 pubmed publisher
Lv Q, Zhen Q, Liu L, Gao R, Yang S, Zhou H, et al. AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells. Life Sci. 2015;131:23-9 pubmed publisher
Wang J, Cao S, Wang A, To E, Law G, Gao J, et al. CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye. Mol Vis. 2015;21:264-72 pubmed
Kim H, W Caspar T, Shah S, Hsieh A. Effects of proinflammatory cytokines on axonal outgrowth from adult rat lumbar dorsal root ganglia using a novel three-dimensional culture system. Spine J. 2015;15:1823-31 pubmed publisher
Takahashi E, Haga A, Tanihara H. Merlin Regulates Epithelial-to-Mesenchymal Transition of ARPE-19 Cells via TAK1-p38MAPK-Mediated Activation. Invest Ophthalmol Vis Sci. 2015;56:2449-58 pubmed publisher
Bruns T, Zimmermann H, Pachnio A, Li K, Trivedi P, Reynolds G, et al. CMV infection of human sinusoidal endothelium regulates hepatic T cell recruitment and activation. J Hepatol. 2015;63:38-49 pubmed publisher
Dudek Perić A, Ferreira G, Muchowicz A, Wouters J, Prada N, Martin S, et al. Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin. Cancer Res. 2015;75:1603-14 pubmed publisher
Fuchs S, Hsieh L, Saarberg W, Erdelmeier C, Wichelhaus T, Schaefer L, et al. Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo. J Cell Mol Med. 2015;19:1021-32 pubmed publisher
Matsuda T, Murao N, Katano Y, Juliandi B, Kohyama J, Akira S, et al. TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus. Nat Commun. 2015;6:6514 pubmed publisher
Kim S, Kim W, Yoon J, Ji J, Morgan M, Cho H, et al. Upregulated RIP3 Expression Potentiates MLKL Phosphorylation-Mediated Programmed Necrosis in Toxic Epidermal Necrolysis. J Invest Dermatol. 2015;135:2021-2030 pubmed publisher
Beggs K, Maiuri A, Fullerton A, Poulsen K, Breier A, Ganey P, et al. Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related. Toxicology. 2015;331:35-46 pubmed publisher
Arcos J, Diangelo L, Scordo J, Sasindran S, Moliva J, Turner J, et al. Lung Mucosa Lining Fluid Modification of Mycobacterium tuberculosis to Reprogram Human Neutrophil Killing Mechanisms. J Infect Dis. 2015;212:948-58 pubmed publisher
de Mare Bredemeijer E, Mancham S, Verstegen M, De Ruiter P, van Gent R, O NEILL D, et al. Human graft-derived mesenchymal stromal cells potently suppress alloreactive T-cell responses. Stem Cells Dev. 2015;24:1436-47 pubmed publisher
Konishi H, Shirabe K, Nakagawara H, Harimoto N, Yamashita Y, Ikegami T, et al. Suppression of silent information regulator 1 activity in noncancerous tissues of hepatocellular carcinoma: Possible association with non-B non-C hepatitis pathogenesis. Cancer Sci. 2015;106:542-9 pubmed publisher
Liu X, Lai F, Yan X, Jiang C, Guo S, Wang C, et al. RIP1 Kinase Is an Oncogenic Driver in Melanoma. Cancer Res. 2015;75:1736-48 pubmed publisher
Leroux L, Dasanayake D, Rommereim L, Fox B, Bzik D, Jardim A, et al. Secreted Toxoplasma gondii molecules interfere with expression of MHC-II in interferon gamma-activated macrophages. Int J Parasitol. 2015;45:319-32 pubmed publisher
Enesa K, Moll H, Luong L, Ferran C, Evans P. A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomes. FASEB J. 2015;29:1869-78 pubmed publisher
Martín R, Sánchez B, Urdaci M, Langella P, Suárez J, Bermúdez Humarán L. Effect of iron on the probiotic properties of the vaginal isolate Lactobacillus jensenii CECT 4306. Microbiology. 2015;161:708-18 pubmed publisher
Lee E, Seong D, Seo J, Jeong M, Lee H, Song J. USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics. Cell Death Differ. 2015;22:1463-76 pubmed publisher
Elsheikh E, Younoszai Z, Otgonsuren M, Hunt S, Raybuck B, Younossi Z. Markers of endothelial dysfunction in patients with non-alcoholic fatty liver disease and coronary artery disease. J Gastroenterol Hepatol. 2014;29:1528-34 pubmed
Yousaf N, Low W, Onipinla A, Mein C, Caulfield M, Munroe P, et al. Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines. Clin Exp Immunol. 2015;180:289-304 pubmed publisher
Ferreira V, Dizzell S, Nazli A, Kafka J, Mueller K, Nguyen P, et al. Medroxyprogesterone Acetate Regulates HIV-1 Uptake and Transcytosis but Not Replication in Primary Genital Epithelial Cells, Resulting in Enhanced T-Cell Infection. J Infect Dis. 2015;211:1745-56 pubmed publisher
Karlberg H, Tan Y, Mirazimi A. Crimean-Congo haemorrhagic fever replication interplays with regulation mechanisms of apoptosis. J Gen Virol. 2015;96:538-46 pubmed publisher
Snyder N, Golin Bisello F, Gao Y, Blair I, Freeman B, Wendell S. 15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways. Chem Biol Interact. 2015;234:144-53 pubmed publisher
Lee H, Ha H, Lee J, Park S, Jeong S, Shin H. The Leaves of Broussonetia kazinoki Siebold Inhibit Atopic Dermatitis-Like Response on Mite Allergen-Treated Nc/Nga Mice. Biomol Ther (Seoul). 2014;22:438-44 pubmed publisher
Goda S, Kato Y, Domae E, Hayashi H, Tani Ishii N, Iida J, et al. Effects of JNK1/2 on the inflammation cytokine TNF-α-enhanced production of MMP-3 in human dental pulp fibroblast-like cells. Int Endod J. 2015;48:1122-8 pubmed publisher
Ishida M, Shimabukuro M, Yagi S, Nishimoto S, Kozuka C, Fukuda D, et al. MicroRNA-378 regulates adiponectin expression in adipose tissue: a new plausible mechanism. PLoS ONE. 2014;9:e111537 pubmed publisher
Suzuki S, Morimoto S, Fujishiro M, Kawasaki M, Hayakawa K, Miyashita T, et al. Inhibition of the insulin-like growth factor system is a potential therapy for rheumatoid arthritis. Autoimmunity. 2015;48:251-8 pubmed publisher
Lee H, Park W, Ryu H, Jeon N. A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation. Biomicrofluidics. 2014;8:054102 pubmed publisher
Zennadi R. MEK inhibitors, novel anti-adhesive molecules, reduce sickle red blood cell adhesion in vitro and in vivo, and vasoocclusion in vivo. PLoS ONE. 2014;9:e110306 pubmed publisher
Raulf N, El Attar R, Kulms D, Lecis D, Delia D, Walczak H, et al. Differential response of head and neck cancer cell lines to TRAIL or Smac mimetics is associated with the cellular levels and activity of caspase-8 and caspase-10. Br J Cancer. 2014;111:1955-64 pubmed publisher
Moriyama K, Kukita A, Li Y, Uehara N, Zhang J, Takahashi I, et al. Regulation of osteoclastogenesis through Tim-3: possible involvement of the Tim-3/galectin-9 system in the modulation of inflammatory bone destruction. Lab Invest. 2014;94:1200-11 pubmed publisher
McIntyre B, Kushwah R, Mechael R, Shapovalova Z, Alev C, Bhatia M. Innate immune response of human pluripotent stem cell-derived airway epithelium. Innate Immun. 2015;21:504-11 pubmed publisher
Davaine J, Quillard T, Brion R, Lapérine O, Guyomarch B, Merlini T, et al. Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability. PLoS ONE. 2014;9:e107642 pubmed publisher
Alexiou P, Papakyriakou A, Ntougkos E, Papaneophytou C, Liepouri F, Mettou A, et al. Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects. Arch Pharm (Weinheim). 2014;347:798-805 pubmed publisher
Lonati P, Brembilla N, Montanari E, Fontao L, Gabrielli A, Vettori S, et al. High IL-17E and low IL-17C dermal expression identifies a fibrosis-specific motif common to morphea and systemic sclerosis. PLoS ONE. 2014;9:e105008 pubmed publisher
Fukuda S, Kohsaka H, Takayasu A, Yokoyama W, Miyabe C, Miyabe Y, et al. Cannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritis. BMC Musculoskelet Disord. 2014;15:275 pubmed publisher
Ji W, Yang M, Praggastis A, Li Y, Zhou H, He Y, et al. Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death. PLoS ONE. 2014;9:e103224 pubmed publisher
Eletxigerra U, Martinez Perdiguero J, Merino S, Villalonga R, Pingarrón J, Campuzano S. Amperometric magnetoimmunoassay for the direct detection of tumor necrosis factor alpha biomarker in human serum. Anal Chim Acta. 2014;838:37-44 pubmed publisher
Cisterne A, Baraz R, Khan N, Welschinger R, Basnett J, Fung C, et al. Silencer of death domains controls cell death through tumour necrosis factor-receptor 1 and caspase-10 in acute lymphoblastic leukemia. PLoS ONE. 2014;9:e103383 pubmed publisher
Donlin L, Jayatilleke A, Giannopoulou E, Kalliolias G, Ivashkiv L. Modulation of TNF-induced macrophage polarization by synovial fibroblasts. J Immunol. 2014;193:2373-83 pubmed publisher
Nymo S, Niyonzima N, Espevik T, Mollnes T. Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology. 2014;219:786-92 pubmed publisher
Chattopadhyay A, Hood B, Conrads T, Redner R. Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD. Mol Cancer Res. 2014;12:1283-91 pubmed publisher
Ottow M, Klaver E, van der Pouw Kraan T, Heijnen P, Laan L, Kringel H, et al. The helminth Trichuris suis suppresses TLR4-induced inflammatory responses in human macrophages. Genes Immun. 2014;15:477-86 pubmed publisher
Kanellis D, Bursac S, Tsichlis P, Volarevic S, Eliopoulos A. Physical and functional interaction of the TPL2 kinase with nucleophosmin. Oncogene. 2015;34:2516-26 pubmed publisher
Li S, Ren J, Xu N, Zhang J, Geng Q, Cao C, et al. MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor. J Mol Cell Cardiol. 2014;75:49-57 pubmed publisher
Pavlosky A, Lau A, Su Y, Lian D, Huang X, Yin Z, et al. RIPK3-mediated necroptosis regulates cardiac allograft rejection. Am J Transplant. 2014;14:1778-90 pubmed publisher
Talbot N, Wheeler Jones C, Cleasby M. Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated skeletal muscle insulin resistance. Mol Cell Endocrinol. 2014;393:129-42 pubmed publisher
Lv X, Qiu M, Chen D, Zheng N, Jin Y, Wu Z. Apigenin inhibits enterovirus 71 replication through suppressing viral IRES activity and modulating cellular JNK pathway. Antiviral Res. 2014;109:30-41 pubmed publisher
Jeong M, Kim J, Lee H, Seo S. Calcitriol May Down-Regulate mRNA Over-Expression of Toll-Like Receptor-2 and -4, LL-37 and Proinflammatory Cytokines in Cultured Human Keratinocytes. Ann Dermatol. 2014;26:296-302 pubmed publisher
Manecka D, Lelievre V, Anouar Y. Inhibition of constitutive TNF production is associated with PACAP-mediated differentiation in PC12 cells. FEBS Lett. 2014;588:3008-14 pubmed publisher
Arenaccio C, Chiozzini C, Columba Cabezas S, Manfredi F, Federico M. Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1. Retrovirology. 2014;11:46 pubmed publisher
Hamilton K, Phong B, Corey C, Cheng J, Gorentla B, ZHONG X, et al. T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10. Sci Signal. 2014;7:ra55 pubmed publisher
Tamarozzi F, Wright H, Johnston K, Edwards S, Turner J, Taylor M. Human filarial Wolbachia lipopeptide directly activates human neutrophils in vitro. Parasite Immunol. 2014;36:494-502 pubmed publisher
Tjin E, Krebbers G, Meijlink K, van de Kasteele W, Rosenberg E, Sanders J, et al. Immune-escape markers in relation to clinical outcome of advanced melanoma patients following immunotherapy. Cancer Immunol Res. 2014;2:538-46 pubmed publisher
Schafer P, Parton A, Capone L, Cedzik D, Brady H, Evans J, et al. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity. Cell Signal. 2014;26:2016-29 pubmed publisher
Suh J, Lee J, Lee G, Chung C, Park Y. Simultaneous imaging and restoration of cell function using cell permeable peptide probe. Biomaterials. 2014;35:6287-98 pubmed publisher
Liu M, Saeki K, Matsunobu T, Okuno T, Koga T, Sugimoto Y, et al. 12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor. J Exp Med. 2014;211:1063-78 pubmed publisher
Chu X, Chen W, Li N, Hu X, Du C, Yu S, et al. Cytosolic double-stranded DNA induces nonnecroptotic programmed cell death in trophoblasts via IFI16. J Infect Dis. 2014;210:1476-86 pubmed publisher
Steenholdt C, Bendtzen K, Brynskov J, Thomsen O, Ainsworth M. Clinical implications of measuring drug and anti-drug antibodies by different assays when optimizing infliximab treatment failure in Crohn's disease: post hoc analysis of a randomized controlled trial. Am J Gastroenterol. 2014;109:1055-64 pubmed publisher
Afshari A, Uhde Stone C, Lu B. Live visualization and quantification of pathway signaling with dual fluorescent and bioluminescent reporters. Biochem Biophys Res Commun. 2014;448:281-6 pubmed publisher
Mizrahi K, Ash S, Peled T, Yaniv I, Stein J, Askenasy N. Negative selection by apoptosis enriches progenitors in naïve and expanded human umbilical cord blood grafts. Bone Marrow Transplant. 2014;49:942-9 pubmed publisher
Konieczkowski D, Johannessen C, Abudayyeh O, Kim J, Cooper Z, Piris A, et al. A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors. Cancer Discov. 2014;4:816-27 pubmed publisher
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product information
Catalog Number :
SRP3177
Product Name :
TNF-α human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE),
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA