This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Sonic Hedgehog human
catalog :
SRP3156
citations: 13
Reference
Bora Singhal N, Perumal D, Nguyen J, Chellappan S. Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer. Neoplasia. 2015;17:538-51 pubmed publisher
Lan T, Kisseleva T, Brenner D. Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation. PLoS ONE. 2015;10:e0129743 pubmed publisher
Fan C, Wang Y, Liu Z, Sun Y, Wang X, Wei G, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015;36:204-14 pubmed publisher
Podjaski C, Alvarez J, Bourbonniere L, Larouche S, Terouz S, Bin J, et al. Netrin 1 regulates blood-brain barrier function and neuroinflammation. Brain. 2015;138:1598-612 pubmed publisher
Tsai C, Hsu F, Tzen K, Liu W, Cheng A, Cheng J. Sonic Hedgehog inhibition as a strategy to augment radiosensitivity of hepatocellular carcinoma. J Gastroenterol Hepatol. 2015;30:1317-24 pubmed publisher
Mimeault M, Rachagani S, Muniyan S, Seshacharyulu P, Johansson S, Datta K, et al. Inhibition of hedgehog signaling improves the anti-carcinogenic effects of docetaxel in prostate cancer. Oncotarget. 2015;6:3887-903 pubmed
Delloye Bourgeois C, Rama N, Brito J, Le Douarin N, Mehlen P. Sonic Hedgehog promotes the survival of neural crest cells by limiting apoptosis induced by the dependence receptor CDON during branchial arch development. Biochem Biophys Res Commun. 2014;452:655-60 pubmed publisher
Hwang J, Kang M, Yoo Y, Quan Y, Kim H, Oh S, et al. The effects of sonic hedgehog signaling pathway components on non-small-cell lung cancer progression and clinical outcome. World J Surg Oncol. 2014;12:268 pubmed publisher
Kwon Y, Jeong M, Leem Y, Lee S, Kim H, Bae G, et al. The Shh coreceptor Cdo is required for differentiation of midbrain dopaminergic neurons. Stem Cell Res. 2014;13:262-74 pubmed publisher
Alfaro A, Roberts B, Kwong L, Bijlsma M, Roelink H. Ptch2 mediates the Shh response in Ptch1-/- cells. Development. 2014;141:3331-9 pubmed publisher
Mondrinos M, Jones P, Finck C, Lelkes P. Engineering de novo assembly of fetal pulmonary organoids. Tissue Eng Part A. 2014;20:2892-907 pubmed publisher
Kumar S, Balczarek K, Lai Z. Evolution of the hedgehog gene family. Genetics. 1996;142:965-72 pubmed
Lanske B, Karaplis A, Lee K, Luz A, Vortkamp A, Pirro A, et al. PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth. Science. 1996;273:663-6 pubmed
product information
Catalog Number :
SRP3156
Product Name :
Sonic Hedgehog human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE),
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA