This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
IL-15 human
catalog :
SRP3077
citations: 19
Reference
Allan A, Sanderson N, Gubbins S, Ellis S, Hammond J. Cattle NK Cell Heterogeneity and the Influence of MHC Class I. J Immunol. 2015;195:2199-206 pubmed publisher
Cany J, van der Waart A, Spanholtz J, Tordoir M, Jansen J, van der Voort R, et al. Combined IL-15 and IL-12 drives the generation of CD34+-derived natural killer cells with superior maturation and alloreactivity potential following adoptive transfer. Oncoimmunology. 2015;4:e1017701 pubmed
Mongini P, Gupta R, Boyle E, Nieto J, Lee H, Stein J, et al. TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells. J Immunol. 2015;195:901-23 pubmed publisher
Brückner S, Agnandji S, Berberich S, Bache E, Fernandes J, Schweiger B, et al. Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial. PLoS Negl Trop Dis. 2015;9:e0003768 pubmed publisher
Yuan H, Meng X, Guo W, Cai P, Li W, Li Q, et al. Transmembrane-Bound IL-15-Promoted Epithelial-Mesenchymal Transition in Renal Cancer Cells Requires the Src-Dependent Akt/GSK-3β/β-Catenin Pathway. Neoplasia. 2015;17:410-20 pubmed publisher
Pierce J, Maples J, Hickner R. IL-15 concentrations in skeletal muscle and subcutaneous adipose tissue in lean and obese humans: local effects of IL-15 on adipose tissue lipolysis. Am J Physiol Endocrinol Metab. 2015;308:E1131-9 pubmed publisher
Boerman G, van Ostaijen Ten Dam M, Kraal K, Santos S, Ball L, Lankester A, et al. Role of NKG2D, DNAM-1 and natural cytotoxicity receptors in cytotoxicity toward rhabdomyosarcoma cell lines mediated by resting and IL-15-activated human natural killer cells. Cancer Immunol Immunother. 2015;64:573-83 pubmed publisher
van der Waart A, Fredrix H, van der Voort R, Schaap N, Hobo W, Dolstra H. siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8(+) T cells in NOD/SCID/IL2Rg(null) mice. Cancer Immunol Immunother. 2015;64:645-54 pubmed publisher
Feng S, Madsen S, Viller N, Neutzsky Wulff A, Geisler C, Karlsson L, et al. Interleukin-15-activated natural killer cells kill autologous osteoclasts via LFA-1, DNAM-1 and TRAIL, and inhibit osteoclast-mediated bone erosion in vitro. Immunology. 2015;145:367-79 pubmed publisher
Broux B, Mizee M, Vanheusden M, van der Pol S, van Horssen J, Van Wijmeersch B, et al. IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis. J Immunol. 2015;194:2099-109 pubmed publisher
Kesarwani P, Al Khami A, Scurti G, Thyagarajan K, Kaur N, Husain S, et al. Promoting thiol expression increases the durability of antitumor T-cell functions. Cancer Res. 2014;74:6036-6047 pubmed publisher
de Rham C, Hadaya K, Bandelier C, Ferrari Lacraz S, Villard J. Expression of killer cell immunoglobulin-like receptors (KIRs) by natural killer cells during acute CMV infection after kidney transplantation. Transpl Immunol. 2014;31:157-64 pubmed publisher
Bunse M, Bendle G, Linnemann C, Bies L, Schulz S, Schumacher T, et al. RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer. Mol Ther. 2014;22:1983-91 pubmed publisher
Leuenberger T, Pfueller C, Luessi F, Bendix I, Paterka M, Prozorovski T, et al. Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase. PLoS ONE. 2014;9:e100871 pubmed publisher
Traitanon O, Gorbachev A, Bechtel J, Keslar K, Baldwin W, Poggio E, et al. IL-15 induces alloreactive CD28(-) memory CD8 T cell proliferation and CTLA4-Ig resistant memory CD8 T cell activation. Am J Transplant. 2014;14:1277-89 pubmed publisher
Sui Y, Hogg A, Wang Y, Frey B, Yu H, Xia Z, et al. Vaccine-induced myeloid cell population dampens protective immunity to SIV. J Clin Invest. 2014;124:2538-49 pubmed publisher
Mishra A, Sullivan L, Caligiuri M. Molecular pathways: interleukin-15 signaling in health and in cancer. Clin Cancer Res. 2014;20:2044-50 pubmed publisher
Nielsen N, Pascal V, Fasth A, Sundström Y, Galsgaard E, Ahern D, et al. Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts. Immunology. 2014;142:581-93 pubmed publisher
Grabstein K, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, et al. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science. 1994;264:965-8 pubmed
product information
Catalog Number :
SRP3077
Product Name :
IL-15 human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE),
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA