This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
IGF-I human
catalog :
SRP3069
citations: 36
Reference
Rahaie A, Toghyani M, Eghbalsaied S. Cotreatment of IGF1 and Fadrozole Upregulates the Expression of RSPO1, SOX9, and AMH in Chicken Embryos. Cells Tissues Organs. 2019;:1-11 pubmed publisher
Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, et al. AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nat Cell Biol. 2019;21:226-237 pubmed publisher
Al Rekabi Z, Wheeler M, Leonard A, Fura A, Juhlin I, Frazar C, et al. Activation of the IGF1 pathway mediates changes in cellular contractility and motility in single-suture craniosynostosis. J Cell Sci. 2016;129:483-91 pubmed publisher
Lippolis C, Refolo M, D Alessandro R, Carella N, Messa C, Cavallini A, et al. Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1. J Exp Clin Cancer Res. 2015;34:90 pubmed publisher
Huang X, Ye H, Feng B, Huang H. Insights into insulin-like peptide system in invertebrates from studies on IGF binding domain-containing proteins in the female mud crab, Scylla paramamosain. Mol Cell Endocrinol. 2015;416:36-45 pubmed publisher
Zhou H, Qian W, Uckun F, Wang L, Wang Y, Chen H, et al. IGF1 Receptor Targeted Theranostic Nanoparticles for Targeted and Image-Guided Therapy of Pancreatic Cancer. ACS Nano. 2015;9:7976-91 pubmed publisher
Frisch C, Zimmermann K, Zilleßen P, Pfeifer A, Racké K, Mayer P. Non-small cell lung cancer cell survival crucially depends on functional insulin receptors. Endocr Relat Cancer. 2015;22:609-21 pubmed publisher
Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M. Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism. Sci Rep. 2015;5:11603 pubmed publisher
Otani H, Yamamoto H, Takaoka M, Sakaguchi M, Soh J, Jida M, et al. TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0129838 pubmed publisher
Anderson J, Kalscheur K, Clapper J, Perry G, Keisler D, Garcia A, et al. Feeding fat from distillers dried grains with solubles to dairy heifers: II. Effects on metabolic profile. J Dairy Sci. 2015;98:5709-19 pubmed publisher
Varewijck A, Lamberts S, van der Lely A, Neggers S, Hofland L, Janssen J. Changes in circulating IGF1 receptor stimulating activity do not parallel changes in total IGF1 during GH treatment of GH-deficient adults. Eur J Endocrinol. 2015;173:119-27 pubmed publisher
Rak A, Drwal E, Karpeta A, Gregoraszczuk E. Regulatory Role of Gonadotropins and Local Factors Produced by Ovarian Follicles on In Vitro Resistin Expression and Action on Porcine Follicular Steroidogenesis. Biol Reprod. 2015;92:142 pubmed publisher
Gao C, Zhi R, Yang Z, Li H, Yan H, Wang X. Low dose of IGF-I increases cell size of skeletal muscle satellite cells via Akt/S6K signaling pathway. J Cell Biochem. 2015;116:2637-48 pubmed publisher
Diot M, Reverchon M, Ramé C, Baumard Y, Dupont J. Expression and effect of NAMPT (visfatin) on progesterone secretion in hen granulosa cells. Reproduction. 2015;150:53-63 pubmed publisher
Olianas M, Dedoni S, Onali P. Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts. Biochem Pharmacol. 2015;95:311-23 pubmed publisher
Fukushima T, Yoshihara H, Furuta H, Kamei H, Hakuno F, Luan J, et al. Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity. Nat Commun. 2015;6:6780 pubmed publisher
Shi S, Wang C, Acton A, Eckert G, Trippel S. Role of sox9 in growth factor regulation of articular chondrocytes. J Cell Biochem. 2015;116:1391-400 pubmed publisher
Kobayashi T, Shiraishi A, Hara Y, Kadota Y, Yang L, Inoue T, et al. Stromal-epithelial interaction study: The effect of corneal epithelial cells on growth factor expression in stromal cells using organotypic culture model. Exp Eye Res. 2015;135:109-17 pubmed publisher
Jang G, Hong I, Kim R, Lee S, Park S, Lee E, et al. Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells. Cancer Res. 2015;75:1691-702 pubmed publisher
Ramirez M, Ornstein A, Luque G, Perez Millan M, Garcia Tornadú I, Rubinstein M, et al. Pituitary and brain dopamine D2 receptors regulate liver gene sexual dimorphism. Endocrinology. 2015;156:1040-51 pubmed publisher
Hutchison M, White P. Prostacyclin regulates bone growth via the Epac/Rap1 pathway. Endocrinology. 2015;156:499-510 pubmed publisher
Suzuki S, Morimoto S, Fujishiro M, Kawasaki M, Hayakawa K, Miyashita T, et al. Inhibition of the insulin-like growth factor system is a potential therapy for rheumatoid arthritis. Autoimmunity. 2015;48:251-8 pubmed publisher
Lamas N, Johnson Kerner B, Roybon L, Kim Y, Garcia Diaz A, Wichterle H, et al. Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures. PLoS ONE. 2014;9:e110324 pubmed publisher
McNally J, Crowe M, Roche J, Beltman M. Effects of physiological and/or disease status on the response of postpartum dairy cows to synchronization of estrus using an intravaginal progesterone device. Theriogenology. 2014;82:1263-72 pubmed publisher
Birk R, Sommer J, Haas D, Faber A, Aderhold C, Schultz J, et al. Influence of static magnetic fields combined with human insulin-like growth factor 1 on human satellite cell cultures. In Vivo. 2014;28:795-802 pubmed
Tian D, Kreeger P. Analysis of the quantitative balance between insulin-like growth factor (IGF)-1 ligand, receptor, and binding protein levels to predict cell sensitivity and therapeutic efficacy. BMC Syst Biol. 2014;8:98 pubmed publisher
Nielsen R, Holm L, Jensen J, Heinemeier K, Remvig L, Kjaer M. Tendon protein synthesis rate in classic Ehlers-Danlos patients can be stimulated with insulin-like growth factor-I. J Appl Physiol (1985). 2014;117:694-8 pubmed publisher
Drexler A, Pietri J, Pakpour N, Hauck E, Wang B, Glennon E, et al. Human IGF1 regulates midgut oxidative stress and epithelial homeostasis to balance lifespan and Plasmodium falciparum resistance in Anopheles stephensi. PLoS Pathog. 2014;10:e1004231 pubmed publisher
Choukair D, Hügel U, Sander A, Uhlmann L, Tönshoff B. Inhibition of IGF-I-related intracellular signaling pathways by proinflammatory cytokines in growth plate chondrocytes. Pediatr Res. 2014;76:245-51 pubmed publisher
Li H, Xu L, Li C, Zhao L, Ma Y, Zheng H, et al. Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells. Mol Cancer. 2014;13:136 pubmed publisher
Mikkelsen J, Resch Z, Kalra B, Savjani G, Kumar A, Conover C, et al. Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity. Oncotarget. 2014;5:1014-25 pubmed
Huang Z, Fang Z, Zhen H, Zhou L, Amin H, Shi P. Inhibition of type I insulin-like growth factor receptor tyrosine kinase by picropodophyllin induces apoptosis and cell cycle arrest in T lymphoblastic leukemia/lymphoma. Leuk Lymphoma. 2014;55:1876-83 pubmed publisher
Li H, Baldwin B, Zahnow C. LIP expression is regulated by IGF-1R signaling and participates in suppression of anoikis. Mol Cancer. 2011;10:100 pubmed publisher
Fiorilli P, Partridge D, Staniszewska I, Wang J, Grabacka M, So K, et al. Integrins mediate adhesion of medulloblastoma cells to tenascin and activate pathways associated with survival and proliferation. Lab Invest. 2008;88:1143-56 pubmed publisher
Gilkes D, Pan Y, Coppola D, Yeatman T, Reuther G, Chen J. Regulation of MDMX expression by mitogenic signaling. Mol Cell Biol. 2008;28:1999-2010 pubmed publisher
D Ercole A. Insulin-like growth factors and their receptors in growth. Endocrinol Metab Clin North Am. 1996;25:573-90 pubmed
product information
Catalog Number :
SRP3069
Product Name :
IGF-I human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE),
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA