This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
PRMT5/MEP50 Active human
catalog :
SRP0145
citations: 5
Reference
Radzisheuskaya A, Shliaha P, Grinev V, Lorenzini E, Kovalchuk S, Shlyueva D, et al. PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia. Nat Struct Mol Biol. 2019;26:999-1012 pubmed publisher
Chitiprolu M, Jagow C, Tremblay V, Bondy Chorney E, Paris G, Savard A, et al. A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy. Nat Commun. 2018;9:2794 pubmed publisher
Likhite N, Jackson C, Liang M, Krzyzanowski M, Lei P, Wood J, et al. The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling. Sci Signal. 2015;8:ra115 pubmed publisher
Gupta N, Madapura M, Bhat U, Rao M. Mapping of Post-translational Modifications of Transition Proteins, TP1 and TP2, and Identification of Protein Arginine Methyltransferase 4 and Lysine Methyltransferase 7 as Methyltransferase for TP2. J Biol Chem. 2015;290:12101-22 pubmed publisher
Wei T, Hsia J, Chiu S, Su L, Juan C, Lee Y, et al. Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis. Cell Signal. 2014;26:2940-50 pubmed publisher
product information
Catalog Number :
SRP0145
Product Name :
PRMT5/MEP50 Active human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
recombinant, expressed in FreeStyle™ 293-F cells, ≥60% (SDS-PAGE)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA