Zhang S, Wu S, Ren J, Chen X, Zhang X, Feng Y, et al. Strategy of blood pressure intervention in the elderly hypertensive patients (STEP): Rational, design, and baseline characteristics for the main trial. Contemp Clin Trials. 2020;89:105913 pubmed publisher

Kono K, Fukuchi Y, Okawa H, Nunoya K, Imawaka H, Watanabe H, et al. Unique Hydrolysis of an Ester-Type Prodrug of Levodopa in Human Plasma: Relay-Type Role Sharing between Alpha-1 Acid Glycoprotein and Human Serum Albumin. Mol Pharm. 2019;16:4131-4138 pubmed publisher

Ikemura N, Yamaori S, Kobayashi C, Kamijo S, Murayama N, Yamazaki H, et al. Inhibitory effects of antihypertensive drugs on human cytochrome P450 2J2 activity: Potent inhibition by azelnidipine and manidipine. Chem Biol Interact. 2019;306:1-9 pubmed publisher

Wunder C, Persu A, Lengelé J, Mg Georges C, Renkin J, Pasquet A, et al. Adherence to antihypertensive drug treatment in patients with apparently treatment-resistant hypertension in the INSPiRED pilot study. Blood Press. 2019;28:168-172 pubmed publisher

Al Harbi N, Imam F, Al Harbi M, Al Shabanah O, Alotaibi M, As Sobeai H, et al. Rutin inhibits carfilzomib-induced oxidative stress and inflammation via the NOS-mediated NF-κB signaling pathway. Inflammopharmacology. 2019;: pubmed publisher

Chen H, Fu W, Wang Z, Wang X, Lei T, Zhu F, et al. Reliability of Docking-Based Virtual Screening for GPCR Ligands with Homology Modeled Structures: A Case Study of the Angiotensin II Type I Receptor. ACS Chem Neurosci. 2019;10:677-689 pubmed publisher

Yu M, Kim D, Park J, Shin S, Lee S, Choi B, et al. Albuminuria during treatment with angiotensin type II receptor blocker is a predictor for GFR decline among non-diabetic hypertensive CKD patients. PLoS ONE. 2018;13:e0202676 pubmed publisher

Zonneveld T, Richard E, Vergouwen M, Nederkoorn P, De Haan R, Roos Y, et al. Blood pressure-lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients with a history of stroke or transient ischaemic attack. Cochrane Database Syst Rev. 2018;7:CD007858 pubmed publisher

Avataneo V, De Nicolò A, Rabbia F, Perlo E, Burrello J, Berra E, et al. Therapeutic drug monitoring-guided definition of adherence profiles in resistant hypertension and identification of predictors of poor adherence. Br J Clin Pharmacol. 2018;84:2535-2543 pubmed publisher

Muraya N, Kadowaki D, Miyamura S, Kitamura K, Uchimura K, Narita Y, et al. Benzbromarone Attenuates Oxidative Stress in Angiotensin II- and Salt-Induced Hypertensive Model Rats. Oxid Med Cell Longev. 2018;2018:7635274 pubmed publisher

Nakamura F, Tsukamoto I, Inoue S, Hashimoto K, Akagi M. Cyclic compressive loading activates angiotensin II type 1 receptor in articular chondrocytes and stimulates hypertrophic differentiation through a G-protein-dependent pathway. FEBS Open Bio. 2018;8:962-973 pubmed publisher

Custodero C, Mankowski R, Lee S, Chen Z, Wu S, Manini T, et al. Evidence-based nutritional and pharmacological interventions targeting chronic low-grade inflammation in middle-age and older adults: A systematic review and meta-analysis. Ageing Res Rev. 2018;46:42-59 pubmed publisher

Alsofany J, Hamza M, Abdelbary A. Fabrication of Nanosuspension Directly Loaded Fast-Dissolving Films for Enhanced Oral Bioavailability of Olmesartan Medoxomil: In Vitro Characterization and Pharmacokinetic Evaluation in Healthy Human Volunteers. AAPS PharmSciTech. 2018;19:2118-2132 pubmed publisher

Kwon S, Hsieh Y, Shin Y, Kang P, Seol G. Linalyl acetate prevents olmesartan-induced intestinal hypermotility mediated by interference of the sympathetic inhibitory pathway in hypertensive rat. Biomed Pharmacother. 2018;102:362-368 pubmed publisher

Brondi A, Garcia J, Trevisan M. Development and Validation of a Chromatography Method Using Tandem UV/Charged Aerosol Detector for Simultaneous Determination of Amlodipine Besylate and Olmesartan Medoxomil: Application to Drug-Excipient Compatibility Study. J Anal Methods Chem. 2017;2017:4878316 pubmed publisher

Shimada H, Kogure N, Noro E, Kudo M, Sugawara K, Sato I, et al. High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in human adrenal cells. FEBS Open Bio. 2017;7:1410-1421 pubmed publisher

Kamo S, Nakanishi T, Aotani R, Nakamura Y, Gose T, Tamai I. Impact of FDA-Approved Drugs on the Prostaglandin Transporter OATP2A1/SLCO2A1. J Pharm Sci. 2017;106:2483-2490 pubmed publisher

Zhou Y, Guan X, Chen X, Yu M, Wang C, Chen X, et al. Angiotensin II/Angiotensin II Receptor Blockade Affects Osteoporosis via the AT1/AT2-Mediated cAMP-Dependent PKA Pathway. Cells Tissues Organs. 2017;204:25-37 pubmed publisher

Gorain B, Choudhury H, Tekade R, Karan S, Jaisankar P, Pal T. Comparative biodistribution and safety profiling of olmesartan medoxomil oil-in-water oral nanoemulsion. Regul Toxicol Pharmacol. 2016;82:20-31 pubmed publisher

Shimoura H, Tanaka H, Matsumoto K, Mochizuki Y, Hatani Y, Hatazawa K, et al. Effects of a changeover from other angiotensin II receptor blockers to olmesartan on left ventricular hypertrophy in heart failure patients. Heart Vessels. 2017;32:584-590 pubmed publisher

Heo S, Yoo G, Choi J, Park H, Park S, Baek S. A rapid method for the simultaneous determination of 25 anti-hypertensive compounds in dietary supplements using ultra-high-pressure liquid chromatography. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016;33:1627-1636 pubmed

Kodati D, Kotakonda H, Yellu N. Population Pharmacokinetic Modeling of Olmesartan, the Active Metabolite of Olmesartan Medoxomil, in Patients with Hypertension. Eur J Drug Metab Pharmacokinet. 2017;42:573-581 pubmed publisher

Hong K, Zhao G, Hong Z, Sun Z, Yang Y, Clifford P, et al. Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles. J Physiol. 2016;594:7027-7047 pubmed publisher

Kourlaba G, Gialama F, Tsioufis K, Maniadakis N. A literature review to evaluate the clinical and economic value of olmesartan for the treatment of hypertensive patients. Int J Cardiol. 2016;221:60-74 pubmed publisher

Catalá López F, Macías Saint Gerons D, González Bermejo D, Rosano G, Davis B, Ridao M, et al. Cardiovascular and Renal Outcomes of Renin-Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Meta-Analyses. PLoS Med. 2016;13:e1001971 pubmed publisher

Golubović J, Birkemeyer C, Protić A, Otašević B, Zečević M. Structure-response relationship in electrospray ionization-mass spectrometry of sartans by artificial neural networks. J Chromatogr A. 2016;1438:123-32 pubmed publisher

Bakhtiari E, Hosseini A, Boroushaki M, Mousavi S. Synergistic, cytotoxic and apoptotic activities of olmesartan with NF-κB inhibitor against HeLa human cell line. Toxicol Mech Methods. 2015;25:614-21 pubmed publisher

Song S, Matsushima N, Lee J, Mendell J. Linear mixed-effects model of QTc prolongation for olmesartan medoxomil. J Clin Pharmacol. 2016;56:96-100 pubmed publisher