This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
AM630
catalog :
SML0327
citations: 144
Reference
Wu Q, Zhang M, Liu X, Zhang J, Wang H. CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus. Int J Mol Med. 2020;45:475-484 pubmed publisher
Du J, Liu Z, Yan Y, Xiong J, Jia X, DI Z, et al. The Cannabinoid WIN 55,212-2 Reduces Delayed Neurologic Sequelae After Carbon Monoxide Poisoning by Promoting Microglial M2 Polarization Through ST2 Signaling. J Mol Neurosci. 2020;70:422-432 pubmed publisher
Lopes J, Bastos J, Costa R, Aguiar D, Moreira F. The roles of cannabinoid CB1 and CB2 receptors in cocaine-induced behavioral sensitization and conditioned place preference in mice. Psychopharmacology (Berl). 2020;237:385-394 pubmed publisher
Zeng J, Li X, Cheng Y, Ke B, Wang R. Activation of cannabinoid receptor type 2 reduces lung ischemia reperfusion injury through PI3K/Akt pathway. Int J Clin Exp Pathol. 2019;12:4096-4105 pubmed
Aly E, Khajah M, Masocha W. β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain. Molecules. 2019;25: pubmed publisher
Petrosino S, Schiano Moriello A, Verde R, Allarà M, Imperatore R, Ligresti A, et al. Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity. J Neuroinflammation. 2019;16:274 pubmed publisher
Koyama S, Purk A, Kaur M, Soini H, Novotny M, Davis K, et al. Beta-caryophyllene enhances wound healing through multiple routes. PLoS ONE. 2019;14:e0216104 pubmed publisher
Mao Y, Huang Y, Zhang Y, Wang C, Wu H, Tian X, et al. Cannabinoid receptor 2‑selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord. Mol Med Rep. 2019;20:5100-5110 pubmed publisher
Wang Z, Lu M, Ren J, Wu X, Long M, Chen L, et al. Electroacupuncture inhibits mast cell degranulation via cannabinoid CB2 receptors in a rat model of allergic contact dermatitis. Acupunct Med. 2019;37:348-355 pubmed publisher
Udoh M, Santiago M, Devenish S, McGregor I, Connor M. Cannabichromene is a cannabinoid CB2 receptor agonist. Br J Pharmacol. 2019;176:4537-4547 pubmed publisher
Mohammadi Vosough E, Baradaran Rahimi V, Masoud S, Mirkarimi H, Demneh M, Abed A, et al. Evaluation of protective effects of non-selective cannabinoid receptor agonist WIN 55,212-2 against the nitroglycerine-induced acute and chronic animal models of migraine: A mechanistic study. Life Sci. 2019;232:116670 pubmed publisher
Dikmen D, Okcay Y, Arslan R, Bektas N. Cannabinoid system involves in the analgesic effect of protocatechuic acid. Daru. 2019;27:605-612 pubmed publisher
Li X, Peng Z, Zhou Y, Wang J, Lin X, Dong X, et al. Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors. Toxicol Lett. 2019;: pubmed publisher
Martin Sanchez A, Warnault V, Montagud Romero S, Pastor A, Mondragón N, de la Torre R, et al. Alcohol-induced conditioned place preference is modulated by CB2 cannabinoid receptors and modifies levels of endocannabinoids in the mesocorticolimbic system. Pharmacol Biochem Behav. 2019;: pubmed publisher
Bai J, Ge G, Wang Y, Zhang W, Wang Q, Wang W, et al. A selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice. Biomed Pharmacother. 2019;116:109025 pubmed publisher
Yao E, Zhang G, Huang J, Yang X, Peng L, Huang X, et al. Immunomodulatory effect of oleoylethanolamide in dendritic cells via TRPV1/AMPK activation. J Cell Physiol. 2019;: pubmed publisher
Masocha W, Thomas A. Indomethacin plus minocycline coadministration relieves chemotherapy and antiretroviral drug-induced neuropathic pain in a cannabinoid receptors-dependent manner. J Pharmacol Sci. 2019;139:325-332 pubmed publisher
Grabiec U, Hohmann T, Ghadban C, Rothgänger C, Wong D, Antonietti A, et al. Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures. Int J Mol Sci. 2019;20: pubmed publisher
Bhatta P, Dhukhwa A, Sheehan K, Al Aameri R, Borse V, Ghosh S, et al. Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea. Sci Rep. 2019;9:4131 pubmed publisher
Rossi F, Tortora C, Palumbo G, Punzo F, Argenziano M, Casale M, et al. CB2 Receptor Stimulation and Dexamethasone Restore the Anti-Inflammatory and Immune-Regulatory Properties of Mesenchymal Stromal Cells of Children with Immune Thrombocytopenia. Int J Mol Sci. 2019;20: pubmed publisher
Espinosa Riquer Z, Ibarra Sanchez A, Vibhushan S, Bratti M, Charles N, Blank U, et al. TLR4 Receptor Induces 2-AG-Dependent Tolerance to Lipopolysaccharide and Trafficking of CB2 Receptor in Mast Cells. J Immunol. 2019;: pubmed publisher
Spiller K, Bi G, He Y, Galaj E, Gardner E, Xi Z. Cannabinoid CB1 and CB2 receptor mechanisms underlie cannabis reward and aversion in rats. Br J Pharmacol. 2019;176:1268-1281 pubmed publisher
Oliveira C, Castor M, Castor C, Costa Á, Ferreira R, Silva J, et al. Evidence for the involvement of opioid and cannabinoid systems in the peripheral antinociception mediated by resveratrol. Toxicol Appl Pharmacol. 2019;369:30-38 pubmed publisher
Myose T, Shirakawa A, Irie K, Yamashita Y, Nakano T, Takase Y, et al. Δ9-Tetrahydrocannabinol elicited 22-kHz ultrasonic vocalization changes after air puff stimulus through CB1 receptor in adult rats. Neurosci Lett. 2019;701:132-135 pubmed publisher
Li L, Dong X, Tu C, Li X, Peng Z, Zhou Y, et al. Opposite effects of cannabinoid CB1 and CB2 receptors on antipsychotic clozapine-induced cardiotoxicity. Br J Pharmacol. 2019;176:890-905 pubmed publisher
Viana T, Bastos J, Costa R, Hott S, Mansur F, Coimbra C, et al. Hypothalamic endocannabinoid signalling modulates aversive responses related to panic attacks. Neuropharmacology. 2019;148:284-290 pubmed publisher
Wang K, Wang Z, Cui R, Chu H. Polysaccharopeptide from Trametes versicolor blocks inflammatory osteoarthritis pain-morphine tolerance effects via activating cannabinoid type 2 receptor. Int J Biol Macromol. 2019;126:805-810 pubmed publisher
Salama R, Abdelsalam R, Abdel Salam O, Khattab M, Salem N, El Khyat Z, et al. Modulation of gastric acid secretion by cannabinoids in rats. J Biochem Mol Toxicol. 2019;33:e22256 pubmed publisher
Huo J, Ma R, Chai X, Liang H, Jiang P, Zhu X, et al. Inhibiting a spinal cord signaling pathway protects against ischemia injury in rats. J Thorac Cardiovasc Surg. 2019;157:494-503.e1 pubmed publisher
Chen T, Xiong Y, Long M, Zheng D, Ke H, Xie J, et al. Electro-acupuncture Pretreatment at Zusanli (ST36) Acupoint Attenuates Lipopolysaccharide-Induced Inflammation in Rats by Inhibiting Ca2+ Influx Associated with Cannabinoid CB2 Receptors. Inflammation. 2019;42:211-220 pubmed publisher
Gobira P, Oliveira A, Gomes J, da Silveira V, Asth L, Bastos J, et al. Opposing roles of CB1 and CB2 cannabinoid receptors in the stimulant and rewarding effects of cocaine. Br J Pharmacol. 2019;176:1541-1551 pubmed publisher
Selvaraj P, Wen J, Tanaka M, Zhang Y. Therapeutic effect of a novel fatty acid amide hydrolase inhibitor PF04457845 in the repetitive closed head injury mouse model. J Neurotrauma. 2018;: pubmed publisher
Cruz S, Sanchez Miranda E, Castillo Arellano J, Cervantes Villagrana R, Ibarra Sanchez A, Gonzalez Espinosa C. Anandamide inhibits FcεRI-dependent degranulation and cytokine synthesis in mast cells through CB2 and GPR55 receptor activation. Possible involvement of CB2-GPR55 heteromers. Int Immunopharmacol. 2018;64:298-307 pubmed publisher
Wang Z, Li Y, Cai S, Li R, Cao G. Cannabinoid receptor 2 agonist attenuates blood‑brain barrier damage in a rat model of intracerebral hemorrhage by activating the Rac1 pathway. Int J Mol Med. 2018;42:2914-2922 pubmed publisher
Salaga M, Binienda A, Tichkule R, Thakur G, Makriyannis A, Storr M, et al. The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome. Eur J Pharmacol. 2018;836:34-43 pubmed publisher
Petrosino S, Verde R, Vaia M, Allarà M, Iuvone T, Di Marzo V. Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis. J Pharmacol Exp Ther. 2018;365:652-663 pubmed publisher
Fogaça M, Campos A, Coelho L, Duman R, Guimarães F. The anxiolytic effects of cannabidiol in chronically stressed mice are mediated by the endocannabinoid system: Role of neurogenesis and dendritic remodeling. Neuropharmacology. 2018;135:22-33 pubmed publisher
Fonseca B, Correia da Silva G, Teixeira N. Cannabinoid-induced cell death in endometrial cancer cells: involvement of TRPV1 receptors in apoptosis. J Physiol Biochem. 2018;74:261-272 pubmed publisher
Wang P, Zheng T, Zhang M, Xu B, Zhang R, Zhang T, et al. Antinociceptive effects of the endogenous cannabinoid peptide agonist VD-hemopressin(β) in mice. Brain Res Bull. 2018;139:48-55 pubmed publisher
Wen J, Jones M, Tanaka M, Selvaraj P, Symes A, Cox B, et al. WWL70 protects against chronic constriction injury-induced neuropathic pain in mice by cannabinoid receptor-independent mechanisms. J Neuroinflammation. 2018;15:9 pubmed publisher
Ferreira R, Castor M, Piscitelli F, Di Marzo V, Duarte I, Romero T. The Involvement of the Endocannabinoid System in the Peripheral Antinociceptive Action of Ketamine. J Pain. 2018;19:487-495 pubmed publisher
Zhang X, Thayer S. Monoacylglycerol lipase inhibitor JZL184 prevents HIV-1 gp120-induced synapse loss by altering endocannabinoid signaling. Neuropharmacology. 2018;128:269-281 pubmed publisher
Köse S, Aerts Kaya F, Köprü Ã, Nemutlu E, KuÅŸkonmaz B, KaraosmanoÄŸlu B, et al. Human bone marrow mesenchymal stem cells secrete endocannabinoids that stimulate in vitro hematopoietic stem cell migration effectively comparable to beta-adrenergic stimulation. Exp Hematol. 2018;57:30-41.e1 pubmed publisher
Wang J, Xu Y, Zhu L, Zou Y, Kong W, Dong B, et al. Cannabinoid receptor 2 as a novel target for promotion of renal cell carcinoma prognosis and progression. J Cancer Res Clin Oncol. 2018;144:39-52 pubmed publisher
Neves L, Gonçalves E, Cavalli J, Vieira G, Laurindo L, Simões R, et al. Photobiomodulation Therapy Improves Acute Inflammatory Response in Mice: the Role of Cannabinoid Receptors/ATP-Sensitive K+ Channel/p38-MAPK Signalling Pathway. Mol Neurobiol. 2018;55:5580-5593 pubmed publisher
Emer A, Donatello N, Batisti A, Oliveira Belmonte L, Santos A, Martins D. The role of the endocannabinoid system in the antihyperalgesic effect of Cedrus atlantica essential oil inhalation in a mouse model of postoperative pain. J Ethnopharmacol. 2018;210:477-484 pubmed publisher
Navarro G, Borroto Escuela D, Angelats E, Etayo Í, Reyes Resina I, Pulido Salgado M, et al. Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia. Brain Behav Immun. 2018;67:139-151 pubmed publisher
Chen I, Cheng J, Tong Y. Metabolic Syndrome Induced Bladder Cannabinoid Receptor Changes in the Fructose-Fed Rats. Low Urin Tract Symptoms. 2018;10:198-203 pubmed publisher
Wasilewski A, Misicka A, Sacharczuk M, Fichna J. Modulation of the endocannabinoid system by the fatty acid amide hydrolase, monoacylglycerol and diacylglycerol lipase inhibitors as an attractive target for secretory diarrhoea therapy. J Physiol Pharmacol. 2017;68:591-596 pubmed
Jing N, Fang B, Wang Z, Ma H. Remote Ischemia Preconditioning Attenuates Blood-Spinal Cord Barrier Breakdown in Rats Undergoing Spinal Cord Ischemia Reperfusion Injury: Associated with Activation and Upregulation of CB1 and CB2 Receptors. Cell Physiol Biochem. 2017;43:2516-2524 pubmed publisher
López Dyck E, Andrade Urzúa F, Elizalde A, Ferrer Villada T, Dagnino Acosta A, Huerta M, et al. ACPA and JWH-133 modulate the vascular tone of superior mesenteric arteries through cannabinoid receptors, BKCa channels, and nitric oxide dependent mechanisms. Pharmacol Rep. 2017;69:1131-1139 pubmed publisher
Cui N, Wang C, Zhao Z, Zhang J, Xu Y, Yang Y, et al. The Roles of Anandamide, Fatty Acid Amide Hydrolase, and Leukemia Inhibitory Factor on the Endometrium during the Implantation Window. Front Endocrinol (Lausanne). 2017;8:268 pubmed publisher
Tian L, Li W, Yang L, Chang N, Fan X, Ji X, et al. Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-?B p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis. Front Immunol. 2017;8:1214 pubmed publisher
Guan T, Zhao G, Duan H, Liu Y, Zhao F. Activation of type 2 cannabinoid receptor (CB2R) by selective agonists regulates the deposition and remodelling of the extracellular matrix. Biomed Pharmacother. 2017;95:1704-1709 pubmed publisher
Couch D, Tasker C, Theophilidou E, Lund J, O Sullivan S. Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon. Clin Sci (Lond). 2017;131:2611-2626 pubmed publisher
Zhang M, Chi M, Zou H, Tian S, Zhang Z, Wang G. Effects of coadministration of low dose cannabinoid type 2 receptor agonist and morphine on vanilloid receptor 1 expression in a rat model of cancer pain. Mol Med Rep. 2017;16:7025-7031 pubmed publisher
Casey S, Atwal N, Vaughan C. Cannabis constituent synergy in a mouse neuropathic pain model. Pain. 2017;158:2452-2460 pubmed publisher
Philpott H, OʼBrien M, McDougall J. Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis. Pain. 2017;158:2442-2451 pubmed publisher
Wasilewski A, Krajewska U, Owczarek K, Lewandowska U, Fichna J. Fatty acid amide hydrolase (FAAH) inhibitor PF-3845 reduces viability, migration and invasiveness of human colon adenocarcinoma Colo-205 cell line: an in vitro study. Acta Biochim Pol. 2017;64:519-525 pubmed publisher
Ji D, Liang Z, Liu G, Zhao G, Fang J. Bufalin attenuates cancer-induced pain and bone destruction in a model of bone cancer. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:1211-1219 pubmed publisher
Gu S, Lee H, Lee T, Song Y, Kim Y, Han K, et al. A synthetic cannabinoid JWH-210 reduces lymphoid organ weights and T-cell activator levels in mice via CB2 receptors. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:1201-1209 pubmed publisher
Celorrio M, Rojo Bustamante E, Fernández Suárez D, Saez E, Estella Hermoso de Mendoza A, Muller C, et al. GPR55: A therapeutic target for Parkinson's disease?. Neuropharmacology. 2017;125:319-332 pubmed publisher
Feliú A, Bonilla Del Río I, Carrillo Salinas F, Hernández Torres G, Mestre L, Puente N, et al. 2-Arachidonoylglycerol Reduces Proteoglycans and Enhances Remyelination in a Progressive Model of Demyelination. J Neurosci. 2017;37:8385-8398 pubmed publisher
Martella A, Sijben H, Rufer A, Grether U, Fingerle J, Ullmer C, et al. A Novel Selective Inverse Agonist of the CB2 Receptor as a Radiolabeled Tool Compound for Kinetic Binding Studies. Mol Pharmacol. 2017;92:389-400 pubmed publisher
Xu C, Hermes D, Nwanguma B, Jacobs I, Mackie K, Mukhopadhyay S, et al. Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. Mol Cell Neurosci. 2017;83:92-102 pubmed publisher
Segat G, Manjavachi M, Matias D, Passos G, Freitas C, Costa R, et al. Antiallodynic effect of ?-caryophyllene on paclitaxel-induced peripheral neuropathy in mice. Neuropharmacology. 2017;125:207-219 pubmed publisher
Sun L, Dong R, Xu X, Yang X, Peng M. Activation of cannabinoid receptor type 2 attenuates surgery-induced cognitive impairment in mice through anti-inflammatory activity. J Neuroinflammation. 2017;14:138 pubmed publisher
Su B, Chen X, Huo J, Guo S, Ma R, Liu Y. The synthetic cannabinoid WIN55212-2 ameliorates traumatic spinal cord injury via inhibition of GAPDH/Siah1 in a CB2-receptor dependent manner. Brain Res. 2017;1671:85-92 pubmed publisher
Seleverstov O, Tobiasz A, Jackson J, Sullivan R, Ma D, Sullivan J, et al. Maternal alcohol exposure during mid-pregnancy dilates fetal cerebral arteries via endocannabinoid receptors. Alcohol. 2017;61:51-61 pubmed publisher
Salazar A, Carozzo A, Correa F, Davio C, Franchi A. Evidence for CB2 receptor involvement in LPS-induced reduction of cAMP intracellular levels in uterine explants from pregnant mice: pathophysiological implications. Mol Hum Reprod. 2017;23:500-508 pubmed publisher
Almeida Santos A, Moreira F, Guimarães F, Aguiar D. 2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. J Psychopharmacol. 2017;31:740-749 pubmed publisher
Qian W, Yin N, Gao F, Miao Y, Li Q, Li F, et al. Cannabinoid CB1 and CB2 receptors differentially modulate L- and T-type Ca2+ channels in rat retinal ganglion cells. Neuropharmacology. 2017;124:143-156 pubmed publisher
Karwad M, Couch D, Theophilidou E, Sarmad S, Barrett D, Larvin M, et al. The role of CB1 in intestinal permeability and inflammation. FASEB J. 2017;31:3267-3277 pubmed publisher
Sergeeva O, De Luca R, Mazur K, Chepkova A, Haas H, Bauer A. N-oleoyldopamine modulates activity of midbrain dopaminergic neurons through multiple mechanisms. Neuropharmacology. 2017;119:111-122 pubmed publisher
Karpińska O, Baranowska Kuczko M, Kloza M, Ambroz Ewicz E, Kozłowski T, Kasacka I, et al. Activation of CB1 receptors by 2-arachidonoylglycerol attenuates vasoconstriction induced by U46619 and angiotensin II in human and rat pulmonary arteries. Am J Physiol Regul Integr Comp Physiol. 2017;312:R883-R893 pubmed publisher
Dotsey E, Ushach I, Pone E, Nakajima R, Jasinskas A, Argueta D, et al. Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice. Sci Rep. 2017;7:42584 pubmed publisher
Li M, Suchland K, Ingram S. Compensatory Activation of Cannabinoid CB2 Receptor Inhibition of GABA Release in the Rostral Ventromedial Medulla in Inflammatory Pain. J Neurosci. 2017;37:626-636 pubmed publisher
Soethoudt M, Grether U, Fingerle J, Grim T, Fezza F, De Petrocellis L, et al. Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. Nat Commun. 2017;8:13958 pubmed publisher
Annunziata P, Cioni C, Mugnaini C, Corelli F. Potent immunomodulatory activity of a highly selective cannabinoid CB2 agonist on immune cells from healthy subjects and patients with multiple sclerosis. J Neuroimmunol. 2017;303:66-74 pubmed publisher
Ferrini M, Hong S, Stierle A, Stierle D, Stella N, Roberts K, et al. CB2 receptors regulate natural killer cells that limit allergic airway inflammation in a murine model of asthma. Allergy. 2017;72:937-947 pubmed publisher
Al Suleimani Y, Al Mahruqi A. The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric oxide-cGMP-dependent vasorelaxant. Eur J Pharmacol. 2017;794:209-215 pubmed publisher
Jiang B, Wang Y, Wang H, Song L, Huang C, Zhu Q, et al. Antidepressant-like effects of fenofibrate in mice via the hippocampal brain-derived neurotrophic factor signalling pathway. Br J Pharmacol. 2017;174:177-194 pubmed publisher
Fung S, Xu C, Hamel E, Wager Miller J, Woodruff G, Miller A, et al. Novel indole-based compounds that differentiate alkylindole-sensitive receptors from cannabinoid receptors and microtubules: Characterization of their activity on glioma cell migration. Pharmacol Res. 2017;115:233-241 pubmed publisher
Matthews A, Lee J, Borazjani A, Mangum L, Hou X, Ross M. Oxyradical stress increases the biosynthesis of 2-arachidonoylglycerol: involvement of NADPH oxidase. Am J Physiol Cell Physiol. 2016;311:C960-C974 pubmed publisher
Nabissi M, Morelli M, Offidani M, Amantini C, Gentili S, Soriani A, et al. Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration. Oncotarget. 2016;7:77543-77557 pubmed publisher
Vaia M, Petrosino S, De Filippis D, Negro L, Guarino A, Carnuccio R, et al. Palmitoylethanolamide reduces inflammation and itch in a mouse model of contact allergic dermatitis. Eur J Pharmacol. 2016;791:669-674 pubmed publisher
Xu J, Tang Y, Xie M, Bie B, Wu J, Yang H, et al. Activation of cannabinoid receptor 2 attenuates mechanical allodynia and neuroinflammatory responses in a chronic post-ischemic pain model of complex regional pain syndrome type I in rats. Eur J Neurosci. 2016;44:3046-3055 pubmed publisher
Karwad M, Macpherson T, Wang B, Theophilidou E, Sarmad S, Barrett D, et al. Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPAR?. FASEB J. 2017;31:469-481 pubmed publisher
Almada M, Amaral C, Diniz da Costa M, Correia da Silva G, Teixeira N, Fonseca B. The endocannabinoid anandamide impairs in vitro decidualization of human cells. Reproduction. 2016;152:351-61 pubmed publisher
Huang Z, Wang H, Wang J, Zhao M, Sun N, Sun F, et al. Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca(2+) oscillations in mouse pancreatic acinar cells. Sci Rep. 2016;6:29757 pubmed publisher
Breuer A, Haj C, Fogaça M, Gomes F, Silva N, Pedrazzi J, et al. Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects. PLoS ONE. 2016;11:e0158779 pubmed publisher
Rossi F, Bellini G, Luongo L, Manzo I, Tolone S, Tortora C, et al. Cannabinoid Receptor 2 as Antiobesity Target: Inflammation, Fat Storage, and Browning Modulation. J Clin Endocrinol Metab. 2016;101:3469-78 pubmed publisher
Kamikubo R, Kai K, Tsuji Naito K, Akagawa M. β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes. Mol Nutr Food Res. 2016;60:2228-2242 pubmed publisher
Gómez Cañas M, Morales P, García Toscano L, Navarrete C, Muñoz E, Jagerovic N, et al. Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile. Pharmacol Res. 2016;110:205-215 pubmed publisher
Lu C, Shi L, Sun B, Zhang Y, Hou B, Sun Y, et al. A Single Intrathecal or Intraperitoneal Injection of CB2 Receptor Agonist Attenuates Bone Cancer Pain and Induces a Time-Dependent Modification of GRK2. Cell Mol Neurobiol. 2017;37:101-109 pubmed publisher
Jia J, Peng J, Li Z, Wu Y, Wu Q, Tu W, et al. Cannabinoid CB2 Receptor Mediates Nicotine-Induced Anti-Inflammation in N9 Microglial Cells Exposed to β Amyloid via Protein Kinase C. Mediators Inflamm. 2016;2016:4854378 pubmed publisher
Cannizzaro C, Malta G, Argo A, Brancato A, Roda G, Casagni E, et al. Behavioural and pharmacological characterization of a novel cannabinomimetic adamantane-derived indole, APICA, and considerations on the possible misuse as a psychotropic spice abuse, in C57bl/6J mice. Forensic Sci Int. 2016;265:6-12 pubmed publisher
Li Y, Kim J. CB2 Cannabinoid Receptor Knockout in Mice Impairs Contextual Long-Term Memory and Enhances Spatial Working Memory. Neural Plast. 2016;2016:9817089 pubmed publisher
Powers M, Breit K, Chester J. Genetic Versus Pharmacological Assessment of the Role of Cannabinoid Type 2 Receptors in Alcohol Reward-Related Behaviors. Alcohol Clin Exp Res. 2015;39:2438-46 pubmed publisher
Zhang M, Wang K, Ma M, Tian S, Wei N, Wang G. Low-Dose Cannabinoid Type 2 Receptor Agonist Attenuates Tolerance to Repeated Morphine Administration via Regulating μ-Opioid Receptor Expression in Walker 256 Tumor-Bearing Rats. Anesth Analg. 2016;122:1031-7 pubmed publisher
Di Giacomo D, De Domenico E, Sette C, Geremia R, Grimaldi P. Type 2 cannabinoid receptor contributes to the physiological regulation of spermatogenesis. FASEB J. 2016;30:1453-63 pubmed publisher
Soliman E, Van Dross R. Anandamide-induced endoplasmic reticulum stress and apoptosis are mediated by oxidative stress in non-melanoma skin cancer: Receptor-independent endocannabinoid signaling. Mol Carcinog. 2016;55:1807-1821 pubmed publisher
Tomić M, Pecikoza U, Micov A, Stepanović Petrović R. The Efficacy of Eslicarbazepine Acetate in Models of Trigeminal, Neuropathic, and Visceral Pain: The Involvement of 5-HT1B/1D Serotonergic and CB1/CB2 Cannabinoid Receptors. Anesth Analg. 2015;121:1632-9 pubmed publisher
Abalo R, Chen C, Vera G, Fichna J, Thakur G, López Pérez A, et al. In vitro and non-invasive in vivo effects of the cannabinoid-1 receptor agonist AM841 on gastrointestinal motor function in the rat. Neurogastroenterol Motil. 2015;27:1721-35 pubmed publisher
Gobira P, Vilela L, Gonçalves B, Santos R, de Oliveira A, Vieira L, et al. Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release. Neurotoxicology. 2015;50:116-21 pubmed publisher
Bitencourt R, Alpár A, Cinquina V, Ferreira S, Pinheiro B, Lemos C, et al. Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents. Neurochem Int. 2015;90:72-84 pubmed publisher
Sophocleous A, Marino S, Logan J, Mollat P, Ralston S, Idris A. Bone Cell-autonomous Contribution of Type 2 Cannabinoid Receptor to Breast Cancer-induced Osteolysis. J Biol Chem. 2015;290:22049-60 pubmed publisher
Wen J, Ribeiro R, Tanaka M, Zhang Y. Activation of CB2 receptor is required for the therapeutic effect of ABHD6 inhibition in experimental autoimmune encephalomyelitis. Neuropharmacology. 2015;99:196-209 pubmed publisher
Hojnik M, Dobovišek L, Knez Z, Ferk P. A synergistic interaction of 17-β-estradiol with specific cannabinoid receptor type 2 antagonist/inverse agonist on proliferation activity in primary human osteoblasts. Biomed Rep. 2015;3:554-558 pubmed
Hassanpour S, Zendehdel M, Babapour V, Charkhkar S. Endocannabinoid and nitric oxide interaction mediates food intake in neonatal chicken. Br Poult Sci. 2015;56:443-51 pubmed publisher
Tang J, Tao Y, Tan L, Yang L, Niu Y, Chen Q, et al. Cannabinoid receptor 2 attenuates microglial accumulation and brain injury following germinal matrix hemorrhage via ERK dephosphorylation in vivo and in vitro. Neuropharmacology. 2015;95:424-33 pubmed publisher
Ikeda H, Ikegami M, Kai M, Kamei J. Cannabinoid functions in the amygdala contribute to conditioned fear memory in streptozotocin-induced diabetic mice: Interaction with glutamatergic functions. Exp Neurol. 2015;269:233-41 pubmed publisher
Deng L, Cornett B, Mackie K, Hohmann A. CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain. Mol Pharmacol. 2015;88:64-74 pubmed publisher
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product information
Catalog Number :
SML0327
Product Name :
AM630
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥90% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA