This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-KRAS antibody produced in mouse
catalog :
SAB1404011
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4F3
reactivity :
human
application :
western blot
citations: 32
Reference
Zeng M, Xiong Y, Safaee N, Nowak R, Donovan K, Yuan C, et al. Exploring Targeted Degradation Strategy for Oncogenic KRASG12C. Cell Chem Biol. 2020;27:19-31.e6 pubmed publisher
Qu L, Yi Z, Zhu S, Wang C, Cao Z, Zhou Z, et al. Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs. Nat Biotechnol. 2019;37:1059-1069 pubmed publisher
Zeng M, Lu J, Li L, Feru F, Quan C, Gero T, et al. Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C. Cell Chem Biol. 2017;24:1005-1016.e3 pubmed publisher
Lu J, Harrison R, Li L, Zeng M, Gondi S, Scott D, et al. KRAS G12C Drug Development: Discrimination between Switch II Pocket Configurations Using Hydrogen/Deuterium-Exchange Mass Spectrometry. Structure. 2017;25:1442-1448.e3 pubmed publisher
Miyo M, Konno M, Nishida N, Sueda T, Noguchi K, Matsui H, et al. Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer. Sci Rep. 2016;6:38415 pubmed publisher
Bukong T, Kodys K, Szabo G. A Novel Human Radixin Peptide Inhibits Hepatitis C Virus Infection at the Level of Cell Entry. Int J Pept Res Ther. 2014;20:269-276 pubmed
Jiao F, Hu H, Yuan C, Wang L, Jiang W, Jin Z, et al. Elevated expression level of long noncoding RNA MALAT-1 facilitates cell growth, migration and invasion in pancreatic cancer. Oncol Rep. 2014;32:2485-92 pubmed publisher
van der Ent W, Burrello C, Teunisse A, Ksander B, van der Velden P, Jager M, et al. Modeling of human uveal melanoma in zebrafish xenograft embryos. Invest Ophthalmol Vis Sci. 2014;55:6612-22 pubmed publisher
Foster J, Wu W, Scott S, Bassi M, Mohan D, Daoud Y, et al. Transforming growth factor β and insulin signal changes in stromal fibroblasts of individual keratoconus patients. PLoS ONE. 2014;9:e106556 pubmed publisher
Li Z, Jiang J, Kong W. Berberine up-regulates hepatic low-density lipoprotein receptor through Ras-independent but AMP-activated protein kinase-dependent Raf-1 activation. Biol Pharm Bull. 2014;37:1766-75 pubmed
Kweon K, Lee C, Jung S, Ban E, Kang S, Jeong J, et al. Sirt1 induction confers resistance to etoposide-induced genotoxic apoptosis in thyroid cancers. Int J Oncol. 2014;45:2065-75 pubmed publisher
Carver J, Dexheimer T, Hsu D, Weng M, Smith J, Guha R, et al. A high-throughput assay for small molecule destabilizers of the KRAS oncoprotein. PLoS ONE. 2014;9:e103836 pubmed publisher
Jiang X, Yu X, Fan J, Guo L, Zhu C, Jiang W, et al. RFT2 is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenesis by sustaining cell proliferation and protecting against cell death. Cancer Lett. 2014;353:78-86 pubmed publisher
Aini W, Miyagawa Hayashino A, Ozeki M, Adeeb S, Hirata M, Tamaki K, et al. Accelerated telomere reduction and hepatocyte senescence in tolerated human liver allografts. Transpl Immunol. 2014;31:55-9 pubmed publisher
van der Ent W, Jochemsen A, Teunisse A, Krens S, Szuhai K, Spaink H, et al. Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53. J Pathol. 2014;233:415-24 pubmed publisher
Vander Griend D, Litvinov I, Isaacs J. Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation. Int J Biol Sci. 2014;10:627-42 pubmed publisher
Lai P, Hsu C, Wang S, Lee J, Tseng M, Hwang J, et al. Production of a neutralizing antibody against envelope protein of dengue virus type 2 using the linear array epitope technique. J Gen Virol. 2014;95:2155-2165 pubmed publisher
Kim J, Jayaprakasha G, Patil B. Obacunone exhibits anti-proliferative and anti-aromatase activity in vitro by inhibiting the p38 MAPK signaling pathway in MCF-7 human breast adenocarcinoma cells. Biochimie. 2014;105:36-44 pubmed publisher
Yeh C, Yen C, Chen Y, Cheng C, Huang S, Chang T, et al. Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumors. Oncotarget. 2014;5:4071-86 pubmed
Iqbal N, Xu L, Devitt C, Skapek S. Isolation and characterization of mammalian cells expressing the Arf promoter during eye development. Biotechniques. 2014;56:239-49 pubmed publisher
Brown D, LASSEGUE B, Lee M, Zafari R, Long J, Saavedra H, et al. Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts. PLoS ONE. 2014;9:e96657 pubmed publisher
Cortez M, Valdecanas D, Zhang X, Zhan Y, Bhardwaj V, Calin G, et al. Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer. Mol Ther. 2014;22:1494-1503 pubmed publisher
Boufraqech M, Zhang L, Jain M, Patel D, Ellis R, Xiong Y, et al. miR-145 suppresses thyroid cancer growth and metastasis and targets AKT3. Endocr Relat Cancer. 2014;21:517-31 pubmed publisher
Bohanon F, Wang X, Ding C, Ding Y, Radhakrishnan G, Rastellini C, et al. Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis. J Surg Res. 2014;190:55-63 pubmed publisher
Wan J, Benkdane M, Alons E, Lotersztajn S, Pavoine C. M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease. Am J Pathol. 2014;184:1763-72 pubmed publisher
Song J, Zheng B, Bu X, Fei Y, Shi S. Negative association of R-Ras activation and breast cancer development. Oncol Rep. 2014;31:2776-84 pubmed publisher
Yang H, Xu W, Li Y, Lan P, Zhang J, Zhang Y, et al. Superior activity of a new histone deacetylase inhibitor (ZYJ-34c) in inhibiting growth of human leukemia cells by inducing p21WAF1 expression and cell cycle arrest. Anticancer Drugs. 2014;25:767-77 pubmed publisher
Wu X, Qi X, Liang M, Li C, Cardona C, Li D, et al. Roles of viroplasm-like structures formed by nonstructural protein NSs in infection with severe fever with thrombocytopenia syndrome virus. FASEB J. 2014;28:2504-16 pubmed publisher
Sakai H, Fujigaki H, Mazur S, Appella E. Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication. Cell Cycle. 2014;13:1015-29 pubmed publisher
He Q, Huang Y, Cai L, Zhang S, Zhang C. Expression and prognostic value of Ars2 in hepatocellular carcinoma. Int J Clin Oncol. 2014;19:880-8 pubmed publisher
Chew T, Liu X, Liu L, Spitsbergen J, Gong Z, Low B. Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models. Oncogene. 2014;33:2717-27 pubmed publisher
Puebla Osorio N, Kim J, Ojeda S, Zhang H, Tavana O, Li S, et al. A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining. Oncogene. 2014;33:2748-57 pubmed publisher
product information
Product No. :
SAB1404011
Product Name :
Monoclonal Anti-KRAS antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
4F3
Applications/Description :
Suitable for capture ELISA; western blot: 1-5 μg/mL; indirect ELISA
Species Reactivity :
human
Isotype :
IgG2aκ
Storage :
Store at -20°C
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA