Anti-Mouse Tlr2 (C-term) antibody produced in rabbit | MilliporeSigma SAB1300199 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MilliporeSigma

other brands :

FLUKA, Sigma-Aldrich, Roche Applied Science

product type :

antibody

product name :

Anti-Mouse Tlr2 (C-term) antibody produced in rabbit

catalog :

SAB1300199

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2a	Bhaskar S, Helen A. Quercetin modulates toll-like receptor-mediated protein kinase signaling pathways in oxLDL-challenged human PBMCs and regulates TLR-activated atherosclerotic inflammation in hypercholesterolemic rats. Mol Cell Biochem. 2016;423:53-65 pubmed
western blot; human; loading ...; fig 4d	Bhaskar S, Sudhakaran P, Helen A. Quercetin attenuates atherosclerotic inflammation and adhesion molecule expression by modulating TLR-NF-?B signaling pathway. Cell Immunol. 2016;310:131-140 pubmed publisher
	Wang D, Jiang Y, Li Z, Xue L, Li X, Liu Y, et al. The Effect of Candida albicans on the Expression Levels of Toll-like Receptor 2 and Interleukin-8 in HaCaT Cells Under High- and Low-glucose Conditions. Indian J Dermatol. 2018;63:201-207 pubmed publisher
	Mendez R, Banerjee S. Proximal Ligation Assay (PLA) on Lung Tissue and Cultured Macrophages to Demonstrate Protein-protein Interaction. Bio Protoc. 2017;7: pubmed publisher

product information

cat no :

SAB1300199

brand :

SIGMA

name :

Anti-Mouse Tlr2 (C-term) antibody produced in rabbit

prod type :

Chemical

name suffix :

IgG fraction of antiserum, buffered aqueous solution

storage :

-20C

storage temp :

-20C

physical form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

shipped in :

dry ice

general description :

TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

ncbi accession no :

NP_036035

syns :

Anti-CD282 antigen; Anti-Toll-like receptor 2

form :

buffered aqueous solution

antibody form :

IgG fraction of antiserum

application(s) :

western blot: 1:100-1:500; indirect ELISA: 1:1000; immunohistochemistry: 1:50-1:100

species reactivity :

mouse, human

immunogen :

TLR2 (NP_036035, 725-760)