This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
SB-525334
catalog :
S8822
citations: 7
Reference
Wei Z, Sakamuru S, Zhang L, Zhao J, Huang R, Kleinstreuer N, et al. Identification and Profiling of Environmental Chemicals That Inhibit the TGFβ/SMAD Signaling Pathway. Chem Res Toxicol. 2019;32:2433-2444 pubmed publisher
Contreras O, Cruz Soca M, Theret M, Soliman H, Tung L, Groppa E, et al. Cross-talk between TGF-β and PDGFRα signaling pathways regulates the fate of stromal fibro-adipogenic progenitors. J Cell Sci. 2019;132: pubmed publisher
Gerbaud P, Pidoux G, Guibourdenche J, Pathirage N, Costa J, Badet J, et al. Mesenchymal activin-A overcomes defective human trisomy 21 trophoblast fusion. Endocrinology. 2011;152:5017-28 pubmed publisher
Thomas M, Docx C, Holmes A, Beach S, Duggan N, England K, et al. Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by mon. Am J Pathol. 2009;174:380-9 pubmed publisher
Laping N, Everitt J, Frazier K, Burgert M, Portis M, Cadacio C, et al. Tumor-specific efficacy of transforming growth factor-beta RI inhibition in Eker rats. Clin Cancer Res. 2007;13:3087-99 pubmed
Higashiyama H, Yoshimoto D, Kaise T, Matsubara S, Fujiwara M, Kikkawa H, et al. Inhibition of activin receptor-like kinase 5 attenuates bleomycin-induced pulmonary fibrosis. Exp Mol Pathol. 2007;83:39-46 pubmed
Grygielko E, Martin W, Tweed C, Thornton P, Harling J, Brooks D, et al. Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis. J Pharmacol Exp Ther. 2005;313:943-51 pubmed
product information
Catalog Number :
S8822
Product Name :
SB-525334
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA