Costa A, Sousa S, Pinto Costa R, Mateus J, Lopes C, Costa A, et al. The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction. elife. 2020;9: pubmed publisher

Di Rita A, Maiorino T, Bruqi K, Volpicelli F, Bellenchi G, Strappazzon F. miR-218 Inhibits Mitochondrial Clearance by Targeting PRKN E3 Ubiquitin Ligase. Int J Mol Sci. 2020;21: pubmed publisher

Yun C, Roh E, Kim S, Han J, Lee J, Jung D, et al. Stem Cell Factor-Inducible MITF-M Expression in Therapeutics for Acquired Skin Hyperpigmentation. Theranostics. 2020;10:340-352 pubmed publisher

Mendes A, Blascke de Mello M, Parente J, Omoto A, Neto Neves E, Fazan R, et al. Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats. Life Sci. 2020;244:117153 pubmed publisher

Mohammadzadeh L, Abnous K, Razavi B, Hosseinzadeh H. Crocin-protected malathion-induced spatial memory deficits by inhibiting TAU protein hyperphosphorylation and antiapoptotic effects. Nutr Neurosci. 2020;23:221-236 pubmed publisher

Rodríguez Fdez S, Citterio C, Lorenzo Martín L, Baltanás Copado J, Llorente Gonzalez C, Corbalan Garcia S, et al. Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output. Cells. 2019;8: pubmed publisher

El Hassouni B, Mantini G, Immordino B, Peters G, Giovannetti E. CX-5461 Inhibits Pancreatic Ductal Adenocarcinoma Cell Growth, Migration and Induces DNA Damage. Molecules. 2019;24: pubmed publisher

Chopra S, Jenney A, Palmer A, Niepel M, Chung M, Mills C, et al. Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells. Cell Syst. 2019;: pubmed publisher

Gülcüler Balta G, Monzel C, Kleber S, Beaudouin J, Balta E, Kaindl T, et al. 3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival. Cell Rep. 2019;29:2295-2306.e6 pubmed publisher

Simões F, Quaresma M, Clarke L, Silva I, Pankonien I, Railean V, et al. TMEM16A chloride channel does not drive mucus production. Life Sci Alliance. 2019;2: pubmed publisher

Nigro E, Distefano G, Chiaravalli M, Matafora V, Castelli M, Pesenti Gritti A, et al. Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness. Sci Rep. 2019;9:16640 pubmed publisher

Randzavola L, Strege K, Juzans M, Asano Y, Stinchcombe J, Gawden Bone C, et al. Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019;129:5600-5614 pubmed publisher

Choi H, Madhu V, Shapiro I, Risbud M. Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation. Sci Rep. 2019;9:15469 pubmed publisher

Granato M, Gilardini Montani M, Zompetta C, Santarelli R, Gonnella R, Romeo M, et al. Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization. Biomolecules. 2019;9: pubmed publisher

Diprima M, Wang D, Tröster A, Maric D, Terrades García N, Ha T, et al. Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma. Mol Oncol. 2019;13:2441-2459 pubmed publisher

Lazzari Dean J, Gest A, Miller E. Optical estimation of absolute membrane potential using fluorescence lifetime imaging. elife. 2019;8: pubmed publisher

Barão F, Barão V, Gornati V, Silvestre G, Silva A, Lacchini S, et al. Study of the Biomechanical and Histological Properties of the Abdominal Aorta of Diabetic Rats Exposed to Cigarette Smoke. J Vasc Res. 2019;56:255-266 pubmed publisher

El Hajj A, Yen F, Oster T, Malaplate C, Pauron L, Corbier C, et al. Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor (LSR) in mice brain. PLoS ONE. 2019;14:e0218812 pubmed publisher

Angele C, Alessandra C, Martina D, Margherita G, Chiara U, Antonella R, et al. Post-translational inhibition of YAP oncogene expression by 4-hydroxynonenal in bladder cancer cells. Free Radic Biol Med. 2019;: pubmed publisher

Finetti F, Cassioli C, Cianfanelli V, Onnis A, Paccagnini E, Kabanova A, et al. The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases. Cell Death Differ. 2019;: pubmed publisher

Di Rienzo M, Antonioli M, Fusco C, Liu Y, Mari M, Orhon I, et al. Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains. Sci Adv. 2019;5:eaau8857 pubmed publisher

Xing Y, Zhang J, Wei H, Zhang H, Guan Y, Wang X, et al. Reduction of the PI3K/Akt related signaling activities in skeletal muscle tissues involves insulin resistance in intrauterine growth restriction rats with catch-up growth. PLoS ONE. 2019;14:e0216665 pubmed publisher

Kho D, Uddin M, Chatterjee M, Vogt A, Raz A, Wu G. GP78 cooperates with DUSP1 to stimulate EGFR-mediated ERK signaling. Mol Cell Biol. 2019;: pubmed publisher

Kang F, Wang S, So E, Chang M, Wong K, Cheng K, et al. Propofol may increase caspase and MAPK pathways, and suppress the Akt pathway to induce apoptosis in MA‑10 mouse Leydig tumor cells. Oncol Rep. 2019;41:3565-3574 pubmed publisher

Ribeiro D, Casarotto P, Spiacci A, Fernandes G, Pinheiro L, Tanus Santos J, et al. Activation of the TRKB receptor mediates the panicolytic-like effect of the NOS inhibitor aminoguanidine. Prog Neuropsychopharmacol Biol Psychiatry. 2019;93:232-239 pubmed publisher

Bomsztyk K, Mar D, Wang Y, Denisenko O, Ware C, Frazar C, et al. PIXUL-ChIP: integrated high-throughput sample preparation and analytical platform for epigenetic studies. Nucleic Acids Res. 2019;: pubmed publisher

Drews K, Calgi M, Harrison W, Drews C, Costa Pinheiro P, Shaw J, et al. Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis. J Virol. 2019;93: pubmed publisher

Cantero M, Almeida R, Morato P, Santos Junior V, Moura C, Amaya Farfan J, et al. The Expression of and Preoperative Correlation between Heat-Shock Protein 70, EuroSCORE, and Lactate in Patients undergoing CABG with Cardiopulmonary Bypass. Braz J Cardiovasc Surg. 2019;34:156-164 pubmed publisher

He W, You Y, Du S, Lei T, Wang H, Li X, et al. Anti-neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells via the regulation of YAP. Oncol Lett. 2019;17:1008-1018 pubmed publisher

Brailoiu E, Chakraborty S, Brailoiu G, Zhao P, Barr J, Ilies M, et al. Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP3-Evoked Ca2+ Signals through Sigma-1 Receptors. Cell Rep. 2019;26:330-337.e4 pubmed publisher

Adzic M, Glavonic E, Nesic M, Milosavljevic M, Mihaljevic M, Petrovic Z, et al. Glucocorticoid receptor alpha translational isoforms as mediators of early adversities and negative emotional states. Prog Neuropsychopharmacol Biol Psychiatry. 2019;90:288-299 pubmed publisher

Blascke de Mello M, Parente J, Schulz R, Castro M. Matrix metalloproteinase (MMP)-2 activation by oxidative stress decreases aortic calponin-1 levels during hypertrophic remodeling in early hypertension. Vascul Pharmacol. 2019;116:36-44 pubmed publisher

Raimondi M, Cesselli D, Di Loreto C, La Marra F, Schneider C, Demarchi F. USP1 (ubiquitin specific peptidase 1) targets ULK1 and regulates its cellular compartmentalization and autophagy. Autophagy. 2019;15:613-630 pubmed publisher

Gilardini Montani M, Santarelli R, Granato M, Gonnella R, Torrisi M, Faggioni A, et al. EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation. Autophagy. 2019;15:652-667 pubmed publisher

Yakhine Diop S, Niso Santano M, Rodríguez Arribas M, Gómez Sánchez R, Martínez Chacón G, Uribe Carretero E, et al. Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson's Disease Patients. Mol Neurobiol. 2019;56:2466-2481 pubmed publisher

Karalis T, Heldin P, Vynios D, Neill T, Buraschi S, Iozzo R, et al. Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors. Matrix Biol. 2019;78-79:118-138 pubmed publisher

Granato M, Gilardini Montani M, Angiolillo C, D Orazi G, Faggioni A, Cirone M. Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1. Viruses. 2018;11: pubmed publisher

Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher

Mu F, Liu T, Zheng H, Xie X, Lei T, He X, et al. Mangiferin induces radiosensitization in glioblastoma cells by inhibiting nonhomologous end joining. Oncol Rep. 2018;40:3663-3673 pubmed publisher

Baumdick M, Gelléri M, Uttamapinant C, Beránek V, Chin J, Bastiaens P. A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation. Nat Commun. 2018;9:3847 pubmed publisher

Savitski M, Zinn N, Faelth Savitski M, Poeckel D, Gade S, Becher I, et al. Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis. Cell. 2018;173:260-274.e25 pubmed publisher

Warth B, Raffeiner P, Granados A, Huan T, Fang M, Forsberg E, et al. Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy. Cell Chem Biol. 2018;25:291-300.e3 pubmed publisher

Yang Y, Lei T, Du S, Tong R, Wang H, Yang J, et al. Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma. Int J Oncol. 2018;52:709-720 pubmed publisher

Iseka F, Goetz B, Mushtaq I, An W, Cypher L, Bielecki T, et al. Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function. J Immunol. 2018;200:483-499 pubmed publisher

Young C, Chira N, Róg J, Al Khalidi R, Benard M, Galas L, et al. Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibition. J Mol Cell Biol. 2018;10:229-242 pubmed publisher

Colecchia D, Stasi M, Leonardi M, Manganelli F, Nolano M, Veneziani B, et al. Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B. Autophagy. 2017;: pubmed publisher

Colasuonno F, Borghi R, Niceforo A, Muzzi M, Bertini E, Di Giulio A, et al. Senescence-associated ultrastructural features of long-term cultures of induced pluripotent stem cells (iPSCs). Aging (Albany NY). 2017;9:2209-2222 pubmed publisher

Venkatachalam G, Surana U, Clement M. Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress. Nucleic Acids Res. 2017;45:10564-10582 pubmed publisher

Mori M, Hazan R, Danielian P, Mahoney J, Li H, LU J, et al. Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis. Nat Commun. 2017;8:15857 pubmed publisher

Alghanem A, Wilkinson E, Emmett M, Aljasir M, Holmes K, Rothermel B, et al. RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells. Angiogenesis. 2017;20:341-358 pubmed publisher

Dai X, Ahn K, Wang L, Kim C, Deivasigamni A, Arfuso F, et al. Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma. Mol Cancer Ther. 2016;15:2966-2976 pubmed

Li L, Zhao J, Liu K, Li G, Han Y, Liu Y. Geniposide prevents rotenone-induced apoptosis in primary cultured neurons. Neural Regen Res. 2015;10:1617-21 pubmed publisher

Wang B, Liu J, Gong Z. Resveratrol induces apoptosis in K562 cells via the regulation of mitochondrial signaling pathways. Int J Clin Exp Med. 2015;8:16926-33 pubmed

Obis T, Hurtado E, Nadal L, Tomàs M, Priego M, Simon A, et al. The novel protein kinase C epsilon isoform modulates acetylcholine release in the rat neuromuscular junction. Mol Brain. 2015;8:80 pubmed publisher

Pereira B, Arruda F, Reis P, Felix T, Santos P, Rafacho B, et al. Tomato (Lycopersicon esculentum) Supplementation Induces Changes in Cardiac miRNA Expression, Reduces Oxidative Stress and Left Ventricular Mass, and Improves Diastolic Function. Nutrients. 2015;7:9640-9 pubmed publisher

Dixon Clarke S, Elkins J, Cheng S, Morin G, Bullock A. Structures of the CDK12/CycK complex with AMP-PNP reveal a flexible C-terminal kinase extension important for ATP binding. Sci Rep. 2015;5:17122 pubmed publisher

Fang X, Qiao H, Groveman B, Feng S, Pflueger M, Xin W, et al. Regulated internalization of NMDA receptors drives PKD1-mediated suppression of the activity of residual cell-surface NMDA receptors. Mol Brain. 2015;8:75 pubmed publisher

Ferreira Barbosa J, Labrie J, Beaudry F, Gagnon C, Jacques M. Actinobacillus pleuropneumoniae induces SJPL cell cycle arrest in G2/M-phase and inhibits porcine reproductive and respiratory syndrome virus replication. Virol J. 2015;12:188 pubmed publisher

Ibach J, Radon Y, Gelléri M, Sonntag M, Brunsveld L, Bastiaens P, et al. Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits. PLoS ONE. 2015;10:e0143162 pubmed publisher

Clarke N, Biscocho J, Kwei K, Davidson J, Sridhar S, Gong X, et al. Integrative Genomics Implicates EGFR as a Downstream Mediator in NKX2-1 Amplified Non-Small Cell Lung Cancer. PLoS ONE. 2015;10:e0142061 pubmed publisher

Varughese E, Kasper S, Anneken E, Yadav J. SHP-2 Mediates Cryptosporidium parvum Infectivity in Human Intestinal Epithelial Cells. PLoS ONE. 2015;10:e0142219 pubmed publisher

Grant N, Coates P, Woods Y, Bray S, Morrice N, Hastie C, et al. Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis. BMC Cancer. 2015;15:885 pubmed publisher

Derive N, Landmann C, Montembault E, Claverie M, Pierre Elies P, Goutte Gattat D, et al. Bub3-BubR1-dependent sequestration of Cdc20Fizzy at DNA breaks facilitates the correct segregation of broken chromosomes. J Cell Biol. 2015;211:517-32 pubmed publisher

Sharma B, Upadhyay R, Dua B, Khan N, Katoch V, Bajaj B, et al. Mycobacterium tuberculosis secretory proteins downregulate T cell activation by interfering with proximal and downstream T cell signalling events. BMC Immunol. 2015;16:67 pubmed publisher

Zu M, Li C, Fang J, Lian W, Liu A, Zheng L, et al. Drug Discovery of Host CLK1 Inhibitors for Influenza Treatment. Molecules. 2015;20:19735-47 pubmed publisher

Kim H, Denli A, Wright R, Baul T, Clemenson G, Morcos A, et al. REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II. J Neurosci. 2015;35:14872-84 pubmed publisher

Lv J, Wang X, Zhang Y, Li D, Zhang J, Sun L. Adsorption between TC-stabilized AuNPs and the phosphate group: application of the PTP1B activity assay. Analyst. 2015;140:8017-22 pubmed publisher

Ito K, Matsuzaki M, Sasahara T, Shin M, Yayama K. Orthovanadate-Induced Vasoconstriction of Rat Mesenteric Arteries Is Mediated by Rho Kinase-Dependent Inhibition of Myosin Light Chain Phosphatase. Biol Pharm Bull. 2015;38:1809-16 pubmed publisher

Aumailley L, Dubois M, Garand C, Marette A, Lebel M. Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase. Exp Gerontol. 2015;72:192-203 pubmed publisher

Li L, Leung D, Goleva E. Activated p38 MAPK in Peripheral Blood Monocytes of Steroid Resistant Asthmatics. PLoS ONE. 2015;10:e0141909 pubmed publisher

Anreddy N, Patel A, Zhang Y, Wang Y, Shukla S, Kathawala R, et al. A-803467, a tetrodotoxin-resistant sodium channel blocker, modulates ABCG2-mediated MDR in vitro and in vivo. Oncotarget. 2015;6:39276-91 pubmed publisher

Huynh H, Ong R, Zopf D. Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer. J Exp Clin Cancer Res. 2015;34:132 pubmed publisher

Arafeh R, Qutob N, Emmanuel R, Keren Paz A, Madore J, Elkahloun A, et al. Recurrent inactivating RASA2 mutations in melanoma. Nat Genet. 2015;47:1408-10 pubmed publisher

Bogen D, Wei J, Azorsa D, Ormanoglu P, Buehler E, Guha R, et al. Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma. Oncotarget. 2015;6:35247-62 pubmed publisher

Aristizabal M, Negri G, Kobor M. The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition. PLoS Genet. 2015;11:e1005608 pubmed publisher

Yu H, Pan B, Weyer A, Wu H, Meng J, Fischer G, et al. CaMKII Controls Whether Touch Is Painful. J Neurosci. 2015;35:14086-102 pubmed publisher

Zhao C, Andersen H, Ozyilmaz B, Ramaprabhu S, Pastorin G, Ho H. Spontaneous and specific myogenic differentiation of human mesenchymal stem cells on polyethylene glycol-linked multi-walled carbon nanotube films for skeletal muscle engineering. Nanoscale. 2015;7:18239-49 pubmed publisher

Chaube B, Malvi P, Singh S, Mohammad N, Meena A, Bhat M. Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression. Oncotarget. 2015;6:37281-99 pubmed publisher

Kurahashi T, Hamashima S, Shirato T, Lee J, Homma T, Kang E, et al. An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy. Biochem Biophys Res Commun. 2015;467:866-71 pubmed publisher

Li J, Duan X, Dong D, Zhang Y, Li W, Zhao L, et al. Hepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice. Int J Environ Res Public Health. 2015;12:12628-42 pubmed publisher

Sinadinos A, Young C, Al Khalidi R, Teti A, Kalinski P, Mohamad S, et al. P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy. PLoS Med. 2015;12:e1001888 pubmed publisher

Santoro M, Guido C, De Amicis F, Sisci D, Cione E, Vincenza D, et al. Bergapten induces metabolic reprogramming in breast cancer cells. Oncol Rep. 2016;35:568-76 pubmed publisher

Chin Y, Yang S, Chang T, Changou C, Lai H, Fu E, et al. Mechanisms of dihydrotestosterone action on resveratrol-induced anti-proliferation in breast cancer cells with different ERα status. Oncotarget. 2015;6:35866-79 pubmed publisher

Cho S, Choi J, Kim J, Cho J, Kim S, Hong S, et al. AKT-independent Reelin signaling requires interactions of heterotrimeric Go and Src. Biochem Biophys Res Commun. 2015;467:1063-9 pubmed publisher

Yoshizaki Y, Mori Y, Tsuzaki Y, Mori T, Nomura N, Wakabayashi M, et al. Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3. Biochem Biophys Res Commun. 2015;467:229-34 pubmed publisher

Indu S, Sekhar S, Sengottaiyan J, Kumar A, Pillai S, Laloraya M, et al. Aberrant Expression of Dynein light chain 1 (DYNLT1) is Associated with Human Male Factor Infertility. Mol Cell Proteomics. 2015;14:3185-95 pubmed publisher

Duncan C, Mohamad S, Young D, Skelton A, Leahy T, Munday D, et al. Human IFNAR2 deficiency: Lessons for antiviral immunity. Sci Transl Med. 2015;7:307ra154 pubmed publisher

Vernekar D, Bhargava P. Yeast Bud27 modulates the biogenesis of Rpc128 and Rpc160 subunits and the assembly of RNA polymerase III. Biochim Biophys Acta. 2015;1849:1340-53 pubmed publisher

Mandai S, Mori T, Sohara E, Rai T, Uchida S. Generation of Hypertension-Associated STK39 Polymorphism Knockin Cell Lines With the Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 System. Hypertension. 2015;66:1199-206 pubmed publisher

Farina A, Cappabianca L, Ruggeri P, Gneo L, Maccarone R, Mackay A. Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity. Oncotarget. 2015;6:35636-51 pubmed publisher

Genzer Y, Dadon M, Burg C, Chapnik N, Froy O. Ketogenic diet delays the phase of circadian rhythms and does not affect AMP-activated protein kinase (AMPK) in mouse liver. Mol Cell Endocrinol. 2015;417:124-30 pubmed publisher

Huang C, Jayakumar T, Chang C, Fong T, Lu S, Thomas P, et al. Hinokitiol Exerts Anticancer Activity through Downregulation of MMPs 9/2 and Enhancement of Catalase and SOD Enzymes: In Vivo Augmentation of Lung Histoarchitecture. Molecules. 2015;20:17720-34 pubmed publisher

Hayano S, Takefuji M, Maeda K, Noda T, Ichimiya H, Kobayashi K, et al. Akt-dependent Girdin phosphorylation regulates repair processes after acute myocardial infarction. J Mol Cell Cardiol. 2015;88:55-63 pubmed publisher

Basheer W, Harris B, Mentrup H, Abreha M, Thames E, Lea J, et al. Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis. J Mol Cell Cardiol. 2015;88:1-13 pubmed publisher

Ingeson Carlsson C, Martinez Monleon A, Nilsson M. Differential effects of MAPK pathway inhibitors on migration and invasiveness of BRAF(V600E) mutant thyroid cancer cells in 2D and 3D culture. Exp Cell Res. 2015;338:127-35 pubmed publisher

Ma Z, Hou T, Shi W, Liu W, He H. Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol. Int J Mol Sci. 2015;16:22062-80 pubmed publisher

Tebbe A, Klammer M, Sighart S, Schaab C, Daub H. Systematic evaluation of label-free and super-SILAC quantification for proteome expression analysis. Rapid Commun Mass Spectrom. 2015;29:795-801 pubmed publisher

Wang X, Jia Q, Xiao J, Jiao H, Lin H. Glucocorticoids retard skeletal muscle development and myoblast protein synthesis through a mechanistic target of rapamycin (mTOR)-signaling pathway in broilers (Gallus gallus domesticus). Stress. 2015;18:686-98 pubmed publisher

Cho K, Lee E, Kim J, Choi J, Kim H, Han S, et al. Proteinase 3 Induces Neuronal Cell Death Through Microglial Activation. Neurochem Res. 2015;40:2242-51 pubmed publisher

Ochoa Ruiz E, Díaz Ruiz R, Hernández Vázquez A, Ibarra González I, Ortiz Plata A, Rembao D, et al. Biotin deprivation impairs mitochondrial structure and function and has implications for inherited metabolic disorders. Mol Genet Metab. 2015;116:204-14 pubmed publisher

Chanoca A, Kovinich N, Burkel B, Stecha S, Bohorquez Restrepo A, Ueda T, et al. Anthocyanin Vacuolar Inclusions Form by a Microautophagy Mechanism. Plant Cell. 2015;27:2545-59 pubmed publisher

Chattopadhyay S, Veleeparambil M, Poddar D, Abdulkhalek S, Bandyopadhyay S, Fensterl V, et al. EGFR kinase activity is required for TLR4 signaling and the septic shock response. EMBO Rep. 2015;16:1535-47 pubmed publisher

Christensen T, Bailey M, Kenyon C, Jensen B, Hunter R. Sodium homeostasis is preserved in a global 11β-hydroxysteroid dehydrogenase type 1 knockout mouse model. Exp Physiol. 2015;100:1362-78 pubmed publisher

Buscà R, Christen R, Lovern M, Clifford A, Yue J, Goss G, et al. ERK1 and ERK2 present functional redundancy in tetrapods despite higher evolution rate of ERK1. BMC Evol Biol. 2015;15:179 pubmed publisher

Shi J, Liu N, Xiao Y, Takei Y, Yasue M, Suzuki Y, et al. The Effects of a Selective CK2 Inhibitor on Anti-glomerular Basement Membrane Glomerulonephritis in Rats. Biol Pharm Bull. 2015;38:1345-51 pubmed publisher

Nakayama A, Morita H, Nakao T, Yamaguchi T, Sumida T, Ikeda Y, et al. A Food-Derived Flavonoid Luteolin Protects against Angiotensin II-Induced Cardiac Remodeling. PLoS ONE. 2015;10:e0137106 pubmed publisher

Wei C, Xiao Q, Kuang X, Zhang T, Yang Z, Wang L. Fucoidan inhibits proliferation of the SKM-1 acute myeloid leukaemia cell line via the activation of apoptotic pathways and production of reactive oxygen species. Mol Med Rep. 2015;12:6649-55 pubmed publisher

Arnaud M, Vallée A, Robert G, Bonneau J, Leroy C, Varin Blank N, et al. CD9, a key actor in the dissemination of lymphoblastic leukemia, modulating CXCR4-mediated migration via RAC1 signaling. Blood. 2015;126:1802-12 pubmed publisher

Shahidullah M, Mandal A, Delamere N. Damage to lens fiber cells causes TRPV4-dependent Src family kinase activation in the epithelium. Exp Eye Res. 2015;140:85-93 pubmed publisher

Lambert R, Srodulski S, Peng X, Margulies K, Despa F, Despa S. Intracellular Na+ Concentration ([Na+]i) Is Elevated in Diabetic Hearts Due to Enhanced Na+-Glucose Cotransport. J Am Heart Assoc. 2015;4:e002183 pubmed publisher

Murphy M, Xiong Y, Pattabiraman G, Manavalan T, Qiu F, Medvedev A. Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling. J Leukoc Biol. 2015;98:963-74 pubmed publisher

Wilhelmsen K, Xu F, Farrar K, Tran A, Khakpour S, Sundar S, et al. Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation. Sci Signal. 2015;8:ra86 pubmed publisher

Giotopoulos G, van der Weyden L, Osaki H, Rust A, Gallipoli P, Meduri E, et al. A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression. J Exp Med. 2015;212:1551-69 pubmed publisher

Garwood C, Ratcliffe L, Morgan S, Simpson J, Owens H, Vazquez Villaseñor I, et al. Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors. Mol Brain. 2015;8:51 pubmed publisher

Rocha M, Godoy K, de Castro P, Hori J, Bom V, Brown N, et al. The Aspergillus fumigatus pkcA G579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model. PLoS ONE. 2015;10:e0135195 pubmed publisher

Gobbo M, Dizeyi N, Abrahamsson P, Bertilsson P, Masitéli V, Pytlowanciv E, et al. Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions. J Diabetes Res. 2015;2015:538529 pubmed publisher

Luc J, Paulin R, Zhao J, Freed D, Michelakis E, Nagendran J. 2-Methoxyestradiol: A Hormonal Metabolite Modulates Stimulated T-Cells Function and proliferation. Transplant Proc. 2015;47:2057-66 pubmed publisher

Sabet O, Stockert R, Xouri G, Brüggemann Y, Stanoev A, Bastiaens P. Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode. Nat Commun. 2015;6:8047 pubmed publisher

Yoshino Y, Ishioka C. Inhibition of glycogen synthase kinase-3 beta induces apoptosis and mitotic catastrophe by disrupting centrosome regulation in cancer cells. Sci Rep. 2015;5:13249 pubmed publisher

De Blasio M, Boije M, Vaughan O, Bernstein B, Davies K, Plein A, et al. Developmental Expression and Glucocorticoid Control of the Leptin Receptor in Fetal Ovine Lung. PLoS ONE. 2015;10:e0136115 pubmed publisher

Goh W, Ow G, Kuznetsov V, Chong S, Lim Y. DLAT subunit of the pyruvate dehydrogenase complex is upregulated in gastric cancer-implications in cancer therapy. Am J Transl Res. 2015;7:1140-51 pubmed

Surico D, Farruggio S, Marotta P, Raina G, Mary D, Surico N, et al. Human Chorionic Gonadotropin Protects Vascular Endothelial Cells from Oxidative Stress by Apoptosis Inhibition, Cell Survival Signalling Activation and Mitochondrial Function Protection. Cell Physiol Biochem. 2015;36:2108-20 pubmed publisher

Kauko O, Laajala T, Jumppanen M, Hintsanen P, Suni V, Haapaniemi P, et al. Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling. Sci Rep. 2015;5:13099 pubmed publisher

Polat A, Karayel Ã, Giese S, Harmanda B, Sanal E, Hu C, et al. Phosphoproteomic Analysis of Aurora Kinase Inhibition in Monopolar Cytokinesis. J Proteome Res. 2015;14:4087-98 pubmed publisher

D Angelo V, Iannotta A, Ramaglia M, Lombardi A, Zarone M, Desiderio V, et al. EZH2 is increased in paediatric T-cell acute lymphoblastic leukemia and is a suitable molecular target in combination treatment approaches. J Exp Clin Cancer Res. 2015;34:83 pubmed publisher

Liu Y, Gai L, Liu J, Cui Y, Zhang Y, Feng J. Expression of poly(C)-binding protein 1 (PCBP1) in NSCLC as a negative regulator of EMT and its clinical value. Int J Clin Exp Pathol. 2015;8:7165-72 pubmed

Ren J, Li Z, Tu C. MiR-135 post-transcriptionally regulates FOXO1 expression and promotes cell proliferation in human malignant melanoma cells. Int J Clin Exp Pathol. 2015;8:6356-66 pubmed

Ramani V, Awasthi S. Toll-like receptor 4-interacting SPA4 peptide suppresses the NLRP3 inflammasome in response to LPS and ATP stimuli. J Leukoc Biol. 2015;98:1037-48 pubmed publisher

Nitta T, Ha D, Galvez F, Miyazawa T, Fan H. Human and murine APOBEC3s restrict replication of koala retrovirus by different mechanisms. Retrovirology. 2015;12:68 pubmed publisher

Shi Y, Ma I, Patel R, Shang X, Zhao Y, Cheng J, et al. NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis. Cell Death Dis. 2015;6:e1841 pubmed publisher

Morris D, Lei B, Longo L, Bomsztyk K, Schwinn D, Michelotti G. Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation. PLoS ONE. 2015;10:e0134442 pubmed publisher

Liu N, Shi J, Xiao Y, Yasue M, Takei Y, Sanefuji H, et al. Effects of a Tricaprylin Emulsion on Anti-glomerular Basement Membrane Glomerulonephritis in Rats: In Vivo and in Silico Studies. Biol Pharm Bull. 2015;38:1175-84 pubmed publisher

Serra H, Chivite I, Angulo Urarte A, Soler A, Sutherland J, Arruabarrena Aristorena A, et al. PTEN mediates Notch-dependent stalk cell arrest in angiogenesis. Nat Commun. 2015;6:7935 pubmed publisher

Jiang W, Wei W, Gaertig M, Li S, Li X. Therapeutic Effect of Berberine on Huntington's Disease Transgenic Mouse Model. PLoS ONE. 2015;10:e0134142 pubmed publisher

O Dell R, Cameron D, Zipfel W, Olson E. Reelin Prevents Apical Neurite Retraction during Terminal Translocation and Dendrite Initiation. J Neurosci. 2015;35:10659-74 pubmed publisher

Tedeschi P, Lin H, Gounder M, Kerrigan J, Abali E, SCOTTO K, et al. Suppression of Cytosolic NADPH Pool by Thionicotinamide Increases Oxidative Stress and Synergizes with Chemotherapy. Mol Pharmacol. 2015;88:720-7 pubmed publisher

Douglas T, Champagne C, Morizot A, Lapointe J, Saleh M. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice. J Immunol. 2015;195:2365-73 pubmed publisher

Husmann K, Ducommun P, Sabile A, Pedersen E, Born W, Fuchs B. Signal transduction and downregulation of C-MET in HGF stimulated low and highly metastatic human osteosarcoma cells. Biochem Biophys Res Commun. 2015;464:1222-1227 pubmed publisher

Succoio M, Comegna M, D Ambrosio C, Scaloni A, Cimino F, Faraonio R. Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence. J Proteomics. 2015;128:18-29 pubmed publisher

Weaver E, Zamora F, Hearne J, Martin Caraballo M. Posttranscriptional regulation of T-type Ca(2+) channel expression by interleukin-6 in prostate cancer cells. Cytokine. 2015;76:309-320 pubmed publisher

Hong J, Sha S, Zhou L, Wang C, Yin J, Chen L. Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons. Cell Death Dis. 2015;6:e1832 pubmed publisher

Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed publisher

Ostrop J, Jozefowski K, Zimmermann S, Hofmann K, Strasser E, Lepenies B, et al. Contribution of MINCLE-SYK Signaling to Activation of Primary Human APCs by Mycobacterial Cord Factor and the Novel Adjuvant TDB. J Immunol. 2015;195:2417-28 pubmed publisher

Mahgoub T, Eustace A, Collins D, Walsh N, O Donovan N, Crown J. Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma. Int J Oncol. 2015;47:900-8 pubmed publisher

Yan L, Liu X, Yin A, Wei Y, Yang Q, Kong B. Huaier aqueous extract inhibits cervical cancer cell proliferation via JNK/p38 pathway. Int J Oncol. 2015;47:1054-60 pubmed publisher

Wu J, Song M, Li T, Zhu Z, Pan J. The Rho-mDia1 signaling pathway is required for cyclic strain-induced cytoskeletal rearrangement of human periodontal ligament cells. Exp Cell Res. 2015;337:28-36 pubmed publisher

Bae E, Chen B, Yan B, Shin B, Cho J, Kim I, et al. Delayed hippocampal neuronal death in young gerbil following transient global cerebral ischemia is related to higher and longer-term expression of p63 in the ischemic hippocampus. Neural Regen Res. 2015;10:944-50 pubmed publisher

Shihabudeen M, Roy D, James J, Thirumurugan K. Chenodeoxycholic acid, an endogenous FXR ligand alters adipokines and reverses insulin resistance. Mol Cell Endocrinol. 2015;414:19-28 pubmed publisher

Patel V, Massenburg D, Vujicic S, Feng L, Tang M, Litbarg N, et al. Apoptotic cells activate AMP-activated protein kinase (AMPK) and inhibit epithelial cell growth without change in intracellular energy stores. J Biol Chem. 2015;290:22352-69 pubmed publisher

Weight C, Jones E, Horn N, Wellner N, Carding S. Elucidating pathways of Toxoplasma gondii invasion in the gastrointestinal tract: involvement of the tight junction protein occludin. Microbes Infect. 2015;17:698-709 pubmed publisher

Arai M, Uchida K, Sadhu S, Ahmed F, Koyano T, Kowithayakorn T, et al. Hedgehog inhibitors from Artocarpus communis and Hyptis suaveolens. Bioorg Med Chem. 2015;23:4150-4 pubmed publisher

Harnett C, Abusneina A, Clément J, Gauthier E. Inhibition of MCL-1 by obatoclax sensitizes Sp2/0-Ag14 hybridoma cells to glutamine deprivation-induced apoptosis. Cell Biochem Funct. 2015;33:334-40 pubmed publisher

Kusunoki Y, Matsui I, Hamano T, Shimomura A, Mori D, Yonemoto S, et al. Excess 25-hydroxyvitamin D3 exacerbates tubulointerstitial injury in mice by modulating macrophage phenotype. Kidney Int. 2015;88:1013-29 pubmed publisher

Zhang Z, Ma W, Wang L, Gong H, Tian Y, Zhang J, et al. Activation of Type 4 Metabotropic Glutamate Receptor Attenuates Oxidative Stress-Induced Death of Neural Stem Cells with Inhibition of JNK and p38 MAPK Signaling. Stem Cells Dev. 2015;24:2709-22 pubmed publisher

Yang X, Zhao E, Zhuang W, Sun F, Han H, Han H, et al. LPA signaling is required for dopaminergic neuron development and is reduced through low expression of the LPA1 receptor in a 6-OHDA lesion model of Parkinson's disease. Neurol Sci. 2015;36:2027-33 pubmed publisher

Garner F, Shomali M, Paquin D, Lyttle C, Hattersley G. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015;26:948-56 pubmed publisher

Biyajima K, Kakizaki F, Shen X, Mori K, Sugai M, Taketo M, et al. Id2 deletion attenuates Apc-deficient ileal tumor formation. Biol Open. 2015;4:993-1001 pubmed publisher

Zhang J, Lv J, Wang X, Li D, Wang Z, Li G. A simple and visible colorimetric method through Zr(4+)-phosphate coordination for the assay of protein tyrosine phosphatase 1B and screening of its inhibitors. Analyst. 2015;140:5716-23 pubmed publisher

Mousseau G, Kessing C, Fromentin R, Trautmann L, Chomont N, Valente S. The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency. MBio. 2015;6:e00465 pubmed publisher

Measso do Bonfim C, Simão Sobrinho J, Lacerda Nogueira R, Salgado Kupper D, Cardoso Pereira Valera F, Lacerda Nogueira M, et al. Differences in Transcriptional Activity of Human Papillomavirus Type 6 Molecular Variants in Recurrent Respiratory Papillomatosis. PLoS ONE. 2015;10:e0132325 pubmed publisher

De Amicis F, Aquila S, Morelli C, Guido C, Santoro M, Perrotta I, et al. Bergapten drives autophagy through the up-regulation of PTEN expression in breast cancer cells. Mol Cancer. 2015;14:130 pubmed publisher

Wang Y, Wang F, Wen S, Guo Y, Liu X, Zhang X, et al. Artesunate-enhanced apoptosis of human high-risk myelodysplastic cells induced by the DNA methyltransferase inhibitor decitabine. Oncol Lett. 2015;9:2449-2454 pubmed

Carnemolla A, Lazell H, Moussaoui S, Bates G. In Vivo Profiling Reveals a Competent Heat Shock Response in Adult Neurons: Implications for Neurodegenerative Disorders. PLoS ONE. 2015;10:e0131985 pubmed publisher

Abraham S, Scarcia M, Bagshaw R, McMahon K, Grant G, Harvey T, et al. A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. Nat Commun. 2015;6:7286 pubmed publisher

Aznar N, Midde K, Dunkel Y, López Sánchez I, Pavlova Y, Marivin A, et al. Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling. elife. 2015;4:e07091 pubmed publisher

Liu Z, Liu W, Huang Y, Guo J, Zhao R, Yang X. Lipopolysaccharide significantly influences the hepatic triglyceride metabolism in growing pigs. Lipids Health Dis. 2015;14:64 pubmed publisher

Cheng C, Cheng J, Chen C, Rau R, Chang Y, Tsaur M. Nerve growth factor-induced synapse-like structures in contralateral sensory ganglia contribute to chronic mirror-image pain. Pain. 2015;156:2295-309 pubmed publisher

Ramos Filho D, Chicaybam G, de Souza Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro Lopes G, et al. High Intensity Interval Training (HIIT) Induces Specific Changes in Respiration and Electron Leakage in the Mitochondria of Different Rat Skeletal Muscles. PLoS ONE. 2015;10:e0131766 pubmed publisher

Hedayatizadeh Omran A, Valadan R, Rafiei A, Tehrani M, Alizadeh Navaei R. VERO stable cell lines expressing full-length human epidermal growth factor receptors 2 and 3: platforms for subtractive phage display. DNA Cell Biol. 2015;34:573-8 pubmed publisher

Yoshino Y, Suzuki M, Takahashi H, Ishioka C. Inhibition of invasion by glycogen synthase kinase-3 beta inhibitors through dysregulation of actin re-organisation via down-regulation of WAVE2. Biochem Biophys Res Commun. 2015;464:275-80 pubmed publisher

Kazlauskaite A, Martínez Torres R, Wilkie S, Kumar A, Peltier J, González A, et al. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. EMBO Rep. 2015;16:939-54 pubmed publisher

Lee J, Homma T, Kurahashi T, Kang E, Fujii J. Oxidative stress triggers lipid droplet accumulation in primary cultured hepatocytes by activating fatty acid synthesis. Biochem Biophys Res Commun. 2015;464:229-35 pubmed publisher

Harvey R, McCaughan C, Wise L, Mercer A, Fleming S. Orf virus inhibits interferon stimulated gene expression and modulates the JAK/STAT signalling pathway. Virus Res. 2015;208:180-8 pubmed publisher

Thompson C, Bloom L, Ogiue Ikeda M, Machida K. SH2-PLA: a sensitive in-solution approach for quantification of modular domain binding by proximity ligation and real-time PCR. BMC Biotechnol. 2015;15:60 pubmed publisher

Vaeth M, Zee I, Concepcion A, Maus M, Shaw P, Portal Celhay C, et al. Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. J Immunol. 2015;195:1202-17 pubmed publisher

Li G, Li J, Tan B, Wang J, Kong X, Guan G, et al. Characterization and Regulation of the Amino Acid Transporter SNAT2 in the Small Intestine of Piglets. PLoS ONE. 2015;10:e0128207 pubmed publisher

Ahmed Z, Timsah Z, Suen K, Cook N, Lee G, Lin C, et al. Grb2 monomer-dimer equilibrium determines normal versus oncogenic function. Nat Commun. 2015;6:7354 pubmed publisher

Crafter C, Vincent J, Tang E, Dudley P, James N, Klinowska T, et al. Combining AZD8931, a novel EGFR/HER2/HER3 signalling inhibitor, with AZD5363 limits AKT inhibitor induced feedback and enhances antitumour efficacy in HER2-amplified breast cancer models. Int J Oncol. 2015;47:446-54 pubmed publisher

Lee S, Jung J, Shin J, Shin K, Cho C, Rhee Y, et al. Immunostimulatory polysaccharide isolated from the leaves of Diospyros kaki Thumb modulate macrophage via TLR2. Int J Biol Macromol. 2015;79:971-82 pubmed publisher

Lim H, Park H, Kim H. Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts. Biochem Pharmacol. 2015;96:337-48 pubmed publisher

Evers van Gogh I, Alex S, Stienstra R, Brenkman A, Kersten S, Kalkhoven E. Electric Pulse Stimulation of Myotubes as an In Vitro Exercise Model: Cell-Mediated and Non-Cell-Mediated Effects. Sci Rep. 2015;5:10944 pubmed publisher

Yang J, Zhou S, Gu J, Wang Y, Guo M, Liu Y. Differences in Unfolded Protein Response Pathway Activation in the Lenses of Three Types of Cataracts. PLoS ONE. 2015;10:e0130705 pubmed publisher

Librán Pérez M, Geurden I, Dias K, Corraze G, Panserat S, Soengas J. Feeding rainbow trout with a lipid-enriched diet: effects on fatty acid sensing, regulation of food intake and cellular signaling pathways. J Exp Biol. 2015;218:2610-9 pubmed publisher

Nishida H, Ikegami A, Kaneko C, Kakuma H, Nishi H, Tanaka N, et al. Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats. PLoS ONE. 2015;10:e0128805 pubmed publisher

Murphy M, Xiong Y, Pattabiraman G, Qiu F, Medvedev A. Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance. J Biol Chem. 2015;290:19218-32 pubmed publisher

Karmakar U, Ishikawa N, Toume K, Arai M, Sadhu S, Ahmed F, et al. Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium. Bioorg Med Chem. 2015;23:4746-54 pubmed publisher

Mizukami T, Togashi Y, Sogabe S, Banno E, Terashima M, De Velasco M, et al. EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition. Int J Oncol. 2015;47:499-505 pubmed publisher

Deng G, Ju X, Meng Q, Yu Z, Ma L. Emodin inhibits the proliferation of PC3 prostate cancer cells in vitro via the Notch signaling pathway. Mol Med Rep. 2015;12:4427-4433 pubmed publisher

Mitra S, Siddiqui W, Khandelwal S. C-Phycocyanin protects against acute tributyltin chloride neurotoxicity by modulating glial cell activity along with its anti-oxidant and anti-inflammatory property: A comparative efficacy evaluation with N-acetyl cysteine in adult rat brain. Chem Biol Interact. 2015;238:138-50 pubmed publisher

Ohnmacht S, Marchetti C, Gunaratnam M, Besser R, Haider S, Di Vita G, et al. A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer. Sci Rep. 2015;5:11385 pubmed publisher

Fujii A, Shearer T, Azuma M. Galectin-3 enhances extracellular matrix associations and wound healing in monkey corneal epithelium. Exp Eye Res. 2015;137:71-8 pubmed publisher

Orlando S, Gallastegui E, Besson A, Abril G, Aligué R, Pujol M, et al. p27Kip1 and p21Cip1 collaborate in the regulation of transcription by recruiting cyclin-Cdk complexes on the promoters of target genes. Nucleic Acids Res. 2015;43:6860-73 pubmed publisher

Cerella C, Muller F, Gaigneaux A, Radogna F, Viry E, Chateauvieux S, et al. Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450. Cell Death Dis. 2015;6:e1782 pubmed publisher

Park O, Ki S, Xu M, Wang H, Feng D, Tam J, et al. Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences. Cell Biosci. 2015;5:25 pubmed publisher

Jarome T, Ferrara N, Kwapis J, Helmstetter F. Contextual Information Drives the Reconsolidation-Dependent Updating of Retrieved Fear Memories. Neuropsychopharmacology. 2015;40:3044-52 pubmed publisher

Stival C, La Spina F, Baró Graf C, Arcelay E, Arranz S, Ferreira J, et al. Src Kinase Is the Connecting Player between Protein Kinase A (PKA) Activation and Hyperpolarization through SLO3 Potassium Channel Regulation in Mouse Sperm. J Biol Chem. 2015;290:18855-64 pubmed publisher

Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S. Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy. Sci Rep. 2015;5:11163 pubmed publisher

Tseng S, Chou M, Chu I. Cetuximab-conjugated iron oxide nanoparticles for cancer imaging and therapy. Int J Nanomedicine. 2015;10:3663-85 pubmed publisher

Bakker N, van Doorn J, Renes J, Donker G, Hokken Koelega A. IGF-1 Levels, Complex Formation, and IGF Bioactivity in Growth Hormone-Treated Children With Prader-Willi Syndrome. J Clin Endocrinol Metab. 2015;100:3041-9 pubmed publisher

You H, Gao T, Cooper T, Morris S, Awad A. Arginase inhibition: a new treatment for preventing progression of established diabetic nephropathy. Am J Physiol Renal Physiol. 2015;309:F447-55 pubmed publisher

Wu L, Wang F, Donly K, Wan C, Luo D, Harris S, et al. Establishment of Immortalized Mouse Bmp2 Knock-Out Dental Papilla Mesenchymal Cells Necessary for Study of Odontoblastic Differentiation and Odontogenesis. J Cell Physiol. 2015;230:2588-95 pubmed publisher

Shinmura K, Kato H, Kawanishi Y, Nagura K, Kamo T, Okubo Y, et al. SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer. Oncol Rep. 2015;34:727-38 pubmed publisher

Abdalla M, Sabbineni H, Prakash R, Ergul A, Fagan S, Somanath P. The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGFβ-induced pulmonary fibrosis. Br J Pharmacol. 2015;172:4173-88 pubmed publisher

Spagnoletti A, Paulesu L, Mannelli C, Ermini L, Romagnoli R, Cintorino M, et al. Low concentrations of Bisphenol A and para-Nonylphenol affect extravillous pathway of human trophoblast cells. Mol Cell Endocrinol. 2015;412:56-64 pubmed publisher

Pérez Luz S, Gimenez Cassina A, Fernández Frías I, Wade Martins R, Díaz Nido J. Delivery of the 135 kb human frataxin genomic DNA locus gives rise to different frataxin isoforms. Genomics. 2015;106:76-82 pubmed publisher

Yue C, Shen S, Deng J, Priceman S, Li W, Huang A, et al. STAT3 in CD8+ T Cells Inhibits Their Tumor Accumulation by Downregulating CXCR3/CXCL10 Axis. Cancer Immunol Res. 2015;3:864-870 pubmed publisher

Parafati M, Lascala A, Morittu V, Trimboli F, Rizzuto A, Brunelli E, et al. Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome. J Nutr Biochem. 2015;26:938-48 pubmed publisher

Karystinou A, Roelofs A, Neve A, Cantatore F, Wackerhage H, De Bari C. Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells. Arthritis Res Ther. 2015;17:147 pubmed publisher

Sekine Y, Togi S, Muromoto R, Kon S, Kitai Y, Yoshimura A, et al. STAP-2 Protein Expression in B16F10 Melanoma Cells Positively Regulates Protein Levels of Tyrosinase, Which Determines Organs to Infiltrate in the Body. J Biol Chem. 2015;290:17462-73 pubmed publisher

Amaral C, Crisma A, Masi L, Martins A, Hirabara S, Curi R. DNA Methylation Changes Induced by a High-Fat Diet and Fish Oil Supplementation in the Skeletal Muscle of Mice. J Nutrigenet Nutrigenomics. 2014;7:314-26 pubmed publisher

Feng S, Wang J, Zhang Y, Creighton C, Ittmann M. FGF23 promotes prostate cancer progression. Oncotarget. 2015;6:17291-301 pubmed

La Torre A, Hoshino A, Cavanaugh C, Ware C, Reh T. The GIPC1-Akt1 Pathway Is Required for the Specification of the Eye Field in Mouse Embryonic Stem Cells. Stem Cells. 2015;33:2674-85 pubmed publisher

de Graaf E, Kaplon J, Mohammed S, Vereijken L, Duarte D, Redondo Gallego L, et al. Signal Transduction Reaction Monitoring Deciphers Site-Specific PI3K-mTOR/MAPK Pathway Dynamics in Oncogene-Induced Senescence. J Proteome Res. 2015;14:2906-14 pubmed publisher

Yu X, He L, Cao P, Yu Q. Eriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3. PLoS ONE. 2015;10:e0128406 pubmed publisher

Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed publisher

Huang Z, Newcomb C, Lei Y, Zhou Y, Bornstein P, Amendt B, et al. Bioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration. Biomaterials. 2015;61:216-28 pubmed publisher

Cox C, Mandell E, STEWART L, Lu R, Johnson D, McCarter S, et al. Endosomal regulation of contact inhibition through the AMOT:YAP pathway. Mol Biol Cell. 2015;26:2673-84 pubmed publisher

Liu C, Lai C, Yen W, Lin Y, Chang H, Tai T, et al. Reciprocal regulation of C-Maf tyrosine phosphorylation by Tec and Ptpn22. PLoS ONE. 2015;10:e0127617 pubmed publisher

Kashyap M, Pore S, Wang Z, Gingrich J, Yoshimura N, Tyagi P. Inflammasomes are important mediators of prostatic inflammation associated with BPH. J Inflamm (Lond). 2015;12:37 pubmed publisher

Doi A, Iijima K, Kano S, Ishizaka Y. Viral protein R of HIV type-1 induces retrotransposition and upregulates glutamate synthesis by the signal transducer and activator of transcription 1 signaling pathway. Microbiol Immunol. 2015;59:398-409 pubmed publisher

Feng X, Szulzewsky F, Yerevanian A, Chen Z, Heinzmann D, Rasmussen R, et al. Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis. Oncotarget. 2015;6:15077-94 pubmed

Cihalova D, Staud F, Ceckova M. Interactions of cyclin-dependent kinase inhibitors AT-7519, flavopiridol and SNS-032 with ABCB1, ABCG2 and ABCC1 transporters and their potential to overcome multidrug resistance in vitro. Cancer Chemother Pharmacol. 2015;76:105-16 pubmed publisher

Rocha G, Villalobos E, Fuentes C, Villarroel P, Reyes M, Díaz X, et al. Preadipocyte proliferation is elevated by calcium sensing receptor activation. Mol Cell Endocrinol. 2015;412:251-6 pubmed publisher

Ward R, Colclough N, Challinor M, Debreczeni J, Eckersley K, Fairley G, et al. Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of ERK1/2. J Med Chem. 2015;58:4790-801 pubmed publisher

Kim J, Kang Y, Lee J, Choi D, Cho Y, Shin J, et al. The natural phytochemical dehydroabietic acid is an anti-aging reagent that mediates the direct activation of SIRT1. Mol Cell Endocrinol. 2015;412:216-25 pubmed publisher

Wasil L, Wei L, Chang C, Lan L, Shair K. Regulation of DNA Damage Signaling and Cell Death Responses by Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) and LMP2A in Nasopharyngeal Carcinoma Cells. J Virol. 2015;89:7612-24 pubmed publisher

Lewkowicz P, Cwiklińska H, Mycko M, Cichalewska M, Domowicz M, Lewkowicz N, et al. Dysregulated RNA-Induced Silencing Complex (RISC) Assembly within CNS Corresponds with Abnormal miRNA Expression during Autoimmune Demyelination. J Neurosci. 2015;35:7521-37 pubmed publisher

Vandana M, Sahoo S. Synergistic activity of combination therapy with PEGylated pemetrexed and gemcitabine for an effective cancer treatment. Eur J Pharm Biopharm. 2015;94:83-93 pubmed publisher

Inoue T, Fujiwara T, Rikitake Y, Maruo T, Mandai K, Kimura K, et al. Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb. J Comp Neurol. 2015;523:1824-39 pubmed publisher

Dixon S, Winter G, Musavi L, Lee E, Snijder B, Rebsamen M, et al. Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death. ACS Chem Biol. 2015;10:1604-9 pubmed publisher

Tang Y, Wang Y, Deosarkar S, Soroush F, Kiani M, Wang B. Fast, Stable Induction of P-Glycoprotein-mediated Drug Resistance in BT-474 Breast Cancer Cells by Stable Transfection of ABCB1 Gene. Anticancer Res. 2015;35:2531-8 pubmed

Kathawala R, Wang Y, Shukla S, Zhang Y, Alqahtani S, Kaddoumi A, et al. ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) are not primary resistance factors for cabazitaxel. Chin J Cancer. 2015;34:115-20 pubmed publisher

Ma W, Yu J, Qi X, Liang L, Zhang Y, Ding Y, et al. Radiation-induced microRNA-622 causes radioresistance in colorectal cancer cells by down-regulating Rb. Oncotarget. 2015;6:15984-94 pubmed

Zhang A, Hitomi M, Bar Shain N, Dalimov Z, Ellis L, Velpula K, et al. Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration. Oncotarget. 2015;6:11640-51 pubmed

Krishnan H, Retzbach E, Ramirez M, Liu T, Li H, Miller W, et al. PKA and CDK5 can phosphorylate specific serines on the intracellular domain of podoplanin (PDPN) to inhibit cell motility. Exp Cell Res. 2015;335:115-22 pubmed publisher

Schwalm C, Jamart C, Benoit N, Naslain D, Prémont C, Prévet J, et al. Activation of autophagy in human skeletal muscle is dependent on exercise intensity and AMPK activation. FASEB J. 2015;29:3515-26 pubmed publisher

Goulopoulou S, Hannan J, Matsumoto T, Ogbi S, Ergul A, Webb R. Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes. Am J Physiol Heart Circ Physiol. 2015;309:H297-304 pubmed publisher

Lee C, Park J, Cho J, Ahn J, Bae E, Won M. Differences in the protein expression levels of Trx2 and Prx3 in the hippocampal CA1 region between adult and aged gerbils following transient global cerebral ischemia. Mol Med Rep. 2015;12:2555-62 pubmed publisher

Iliuk A, Jayasundera K, Wang W, Schluttenhofer R, Geahlen R, Tao W. In-Depth Analyses of B Cell Signaling Through Tandem Mass Spectrometry of Phosphopeptides Enriched by PolyMAC. Int J Mass Spectrom. 2015;377:744-753 pubmed

Venugopal S, Chen M, Liao W, Er S, Wong W, Ge R. Isthmin is a novel vascular permeability inducer that functions through cell-surface GRP78-mediated Src activation. Cardiovasc Res. 2015;107:131-42 pubmed publisher

Zhao X, Fu J, Xu A, Yu L, Zhu J, Dai R, et al. Gankyrin drives malignant transformation of chronic liver damage-mediated fibrosis via the Rac1/JNK pathway. Cell Death Dis. 2015;6:e1751 pubmed publisher

Nygaard H, Kaufman A, Sekine Konno T, Huh L, Going H, Feldman S, et al. Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer's disease mouse model. Alzheimers Res Ther. 2015;7:25 pubmed publisher

Choi H, Jeon H, Lee O, Lee B. Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high-fat diet-fed zebrafish and mice: Inhibition of early adipogenesis via cell-cycle arrest and AMPKα activation. Mol Nutr Food Res. 2015;59:1458-71 pubmed publisher

Travaglia A, Pietropaolo A, Di Martino R, Nicoletti V, La Mendola D, Calissano P, et al. A small linear peptide encompassing the NGF N-terminus partly mimics the biological activities of the entire neurotrophin in PC12 cells. ACS Chem Neurosci. 2015;6:1379-92 pubmed publisher

Mariano G, Ricciardi M, Trisciuoglio D, Zampieri M, Ciccarone F, Guastafierro T, et al. PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression. Oncotarget. 2015;6:15008-21 pubmed

Behr C, Hesketh A, Barlow M, Glick R, Symons M, Steinberg B, et al. Celecoxib inhibits Ewing sarcoma cell migration via actin modulation. J Surg Res. 2015;198:424-33 pubmed publisher

Ortutay Z, Oksanen A, Aittomäki S, Ortutay C, Pesu M. Proprotein convertase FURIN regulates T cell receptor-induced transactivation. J Leukoc Biol. 2015;98:73-83 pubmed publisher

Cao S, Moss W, O Grady T, Concha M, Strong M, Wang X, et al. New Noncoding Lytic Transcripts Derived from the Epstein-Barr Virus Latency Origin of Replication, oriP, Are Hyperedited, Bind the Paraspeckle Protein, NONO/p54nrb, and Support Viral Lytic Transcription. J Virol. 2015;89:7120-32 pubmed publisher

Iram S, Gruber S, Raguimova O, Thomas D, Robia S. ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening. Mol Pharmacol. 2015;88:84-94 pubmed publisher

Lee Y, Gao Q, Kim E, Lee Y, Park S, Lee H, et al. Pretreatment with 5-hydroxymethyl-2-furaldehyde blocks scopolamine-induced learning deficit in contextual and spatial memory in male mice. Pharmacol Biochem Behav. 2015;134:57-64 pubmed publisher

Guan N, Svennersten K, De Verdier P, Wiklund N, Gustafsson L. Receptors involved in the modulation of guinea pig urinary bladder motility by prostaglandin D2. Br J Pharmacol. 2015;172:4024-37 pubmed publisher

Cascio G, Martín Cófreces N, Rodríguez Frade J, López Cotarelo P, Criado G, Pablos J, et al. CXCL12 Regulates through JAK1 and JAK2 Formation of Productive Immunological Synapses. J Immunol. 2015;194:5509-19 pubmed publisher

Park S, Park J, Han A, Davaatseren M, Kim H, Kim M, et al. Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells via activation of AMP-activated protein kinase. Cell Biochem Funct. 2015;33:220-5 pubmed publisher

Carelli Alinovi C, Giardina B, Misiti F. Amyloid beta peptide (1-42)-mediated antioxidant imbalance is associated with activation of protein kinase C in red blood cells. Cell Biochem Funct. 2015;33:196-201 pubmed publisher

Kaushansky N, Eisenstein M, Boura Halfon S, Hansen B, Nielsen C, Milo R, et al. Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease. J Biol Chem. 2015;290:15260-78 pubmed publisher

Bonsignore L, Butler J, Klinge C, Schaner Tooley C. Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis. Oncotarget. 2015;6:12248-63 pubmed

Liu H, Li L, Voss C, Wang F, Liu J, Li S. A Comprehensive Immunoreceptor Phosphotyrosine-based Signaling Network Revealed by Reciprocal Protein-Peptide Array Screening. Mol Cell Proteomics. 2015;14:1846-58 pubmed publisher

Xu Y, Sheng H, Tang Z, Lu J, Ni X. Inflammation and increased IDO in hippocampus contribute to depression-like behavior induced by estrogen deficiency. Behav Brain Res. 2015;288:71-8 pubmed publisher

Alkhateeb A, Buckett P, Gardeck A, Kim J, Byrne S, Fraenkel P, et al. The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro. Am J Physiol Gastrointest Liver Physiol. 2015;308:G1019-26 pubmed publisher

Park G, Yoon B, Kim Y, Choi S, Moon J, Kwon S, et al. Conversion of mouse fibroblasts into cardiomyocyte-like cells using small molecule treatments. Biomaterials. 2015;54:201-12 pubmed publisher

Gillis E, Williams J, Garrett M, Mooney J, Sasser J. The Dahl salt-sensitive rat is a spontaneous model of superimposed preeclampsia. Am J Physiol Regul Integr Comp Physiol. 2015;309:R62-70 pubmed publisher

Pasqua T, Filice E, Mazza R, Quintieri A, Carmela Cerra M, Iannacone R, et al. Cardiac and hepatic role of r-AtHSP70: basal effects and protection against ischemic and sepsis conditions. J Cell Mol Med. 2015;19:1492-503 pubmed publisher

Zou Z, Cai Y, Chen Y, Chen S, Liu L, Shen Z, et al. Bone marrow-derived mesenchymal stem cells attenuate acute liver injury and regulate the expression of fibrinogen-like-protein 1 and signal transducer and activator of transcription 3. Mol Med Rep. 2015;12:2089-97 pubmed publisher

Cheng Y, Guo X, Gong Y, Ding X, Yu Y. Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis. Mol Med Rep. 2015;12:2009-14 pubmed publisher

Moldenhauer L, Cockshell M, Frost L, Parham K, Tvorogov D, Tan L, et al. Interleukin-3 greatly expands non-adherent endothelial forming cells with pro-angiogenic properties. Stem Cell Res. 2015;14:380-95 pubmed publisher

Bhalla N, Formisano N, Miodek A, Jain A, Di Lorenzo M, Pula G, et al. Plasmonic ruler on field-effect devices for kinase drug discovery applications. Biosens Bioelectron. 2015;71:121-128 pubmed publisher

Skwarska A, Augustin E, Beffinger M, Wojtczyk A, Konicz S, Laskowska K, et al. Targeting of FLT3-ITD kinase contributes to high selectivity of imidazoacridinone C-1311 against FLT3-activated leukemia cells. Biochem Pharmacol. 2015;95:238-52 pubmed publisher

Huan C, Wang Y, Ni B, Wang R, Huang L, Ren X, et al. Porcine epidemic diarrhea virus uses cell-surface heparan sulfate as an attachment factor. Arch Virol. 2015;160:1621-8 pubmed publisher

Sharon C, Baranwal S, Patel N, Rodriguez Agudo D, Pandak W, Majumdar A, et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. Oncotarget. 2015;6:15332-47 pubmed

Cho Y, Shin M, Ko I, Kim S, Kim C, Sung Y, et al. Ulinastatin inhibits cerebral ischemia-induced apoptosis in the hippocampus of gerbils. Mol Med Rep. 2015;12:1796-802 pubmed publisher

Gupta J, Igea A, Papaioannou M, López Casas P, Llonch E, Hidalgo M, et al. Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors. Oncotarget. 2015;6:8539-51 pubmed

Olianas M, Dedoni S, Onali P. Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts. Biochem Pharmacol. 2015;95:311-23 pubmed publisher

Yang T, Shi R, Chang L, Tang K, Chen K, Yu G, et al. Huachansu suppresses human bladder cancer cell growth through the Fas/Fasl and TNF- alpha/TNFR1 pathway in vitro and in vivo. J Exp Clin Cancer Res. 2015;34:21 pubmed publisher

Schläpfer M, Piegeler T, Dull R, Schwartz D, Mao M, Bonini M, et al. Propofol increases morbidity and mortality in a rat model of sepsis. Crit Care. 2015;19:45 pubmed publisher

Chen H, Guan R, Lei Y, Chen J, Ge Q, Zhang X, et al. Lymphangiogenesis in gastric cancer regulated through Akt/mTOR-VEGF-C/VEGF-D axis. BMC Cancer. 2015;15:103 pubmed publisher

Sahoo S, Shaikh S, Sopariwala D, Bal N, Bruhn D, Kopeć W, et al. The N Terminus of Sarcolipin Plays an Important Role in Uncoupling Sarco-endoplasmic Reticulum Ca2+-ATPase (SERCA) ATP Hydrolysis from Ca2+ Transport. J Biol Chem. 2015;290:14057-67 pubmed publisher

Choi U, Choi W, Hur J, Kim Y. Polyubiquitin chain-dependent protein degradation in TRIM30 cytoplasmic bodies. Exp Mol Med. 2015;47:e159 pubmed publisher

D Andrea I, Fardella V, Fardella S, Pallante F, Ghigo A, Iacobucci R, et al. Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling. EMBO Mol Med. 2015;7:904-17 pubmed publisher

Papadopoulos C, Orso G, Mancuso G, Herholz M, Gumeni S, Tadepalle N, et al. Spastin binds to lipid droplets and affects lipid metabolism. PLoS Genet. 2015;11:e1005149 pubmed publisher

Bolisetty S, Zarjou A, Hull T, Traylor A, Perianayagam A, Joseph R, et al. Macrophage and epithelial cell H-ferritin expression regulates renal inflammation. Kidney Int. 2015;88:95-108 pubmed publisher

Zoratti G, Tanabe L, Varela F, Murray A, Bergum C, Colombo Ã, et al. Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling. Nat Commun. 2015;6:6776 pubmed publisher

Yin G, Chen J, Wei S, Wang H, Chen Q, Lin Y, et al. Adenoviral vector-mediated overexpression of osteoprotegerin accelerates osteointegration of titanium implants in ovariectomized rats. Gene Ther. 2015;22:636-44 pubmed publisher

Blanco B, Herrero Sánchez M, Rodríguez Serrano C, Sánchez Barba M, Del Cañizo M. Profound blockade of T cell activation requires concomitant inhibition of different class I PI3K isoforms. Immunol Res. 2015;62:175-88 pubmed publisher

Lu J, Luo C, Bali K, Xie R, Mains R, Eipper B, et al. A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses. Nat Commun. 2015;6:6820 pubmed publisher

Chinen I, Nakahama T, Kimura A, Nguyen N, Takemori H, Kumagai A, et al. The aryl hydrocarbon receptor/microRNA-212/132 axis in T cells regulates IL-10 production to maintain intestinal homeostasis. Int Immunol. 2015;27:405-15 pubmed publisher

Khodabukus A, Baehr L, Bodine S, Baar K. Role of contraction duration in inducing fast-to-slow contractile and metabolic protein and functional changes in engineered muscle. J Cell Physiol. 2015;230:2489-97 pubmed publisher

Xu X, Zhang Z, Chen Y, Yuan M, Yuan S, Bao J. Antiviral and antitumor activities of the lectin extracted from Aspidistra elatior. Z Naturforsch C J Biosci. 2015;70:7-13 pubmed publisher

Urbańska K, Pajak B, Orzechowski A, Sokołowska J, Grodzik M, Sawosz E, et al. The effect of silver nanoparticles (AgNPs) on proliferation and apoptosis of in ovo cultured glioblastoma multiforme (GBM) cells. Nanoscale Res Lett. 2015;10:98 pubmed publisher

Maubant S, Tesson B, Maire V, Ye M, Rigaill G, Gentien D, et al. Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells. PLoS ONE. 2015;10:e0122333 pubmed publisher

Schmid C, Robinson M, Scheifinger N, Müller S, Cogliatti S, Tzankov A, et al. DUSP4 deficiency caused by promoter hypermethylation drives JNK signaling and tumor cell survival in diffuse large B cell lymphoma. J Exp Med. 2015;212:775-92 pubmed publisher

Aubert L, Guilbert M, Corbet C, Génot E, Adriaenssens E, Chassat T, et al. NGF-induced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib. Oncotarget. 2015;6:9807-19 pubmed

Jeong S, Cho G. Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells. Biochem Biophys Res Commun. 2015;460:971-6 pubmed publisher

Yu Y, Jian M, Wang Y, Han R. Propofol ameliorates calpain-induced collapsin response mediator protein-2 proteolysis in traumatic brain injury in rats. Chin Med J (Engl). 2015;128:919-27 pubmed publisher

Mohan R, Atreja S. Tyrosine phosphorylation of cytochrome c as a signaling event in frozen thawed buffalo spermatozoa at the cross-roads of capacitation and apoptosis. Cryobiology. 2015;70:253-61 pubmed publisher

Stephenson S, Douglas E, Mertens Walker I, Lisle J, Maharaj M, Herington A. Anti-tumour effects of antibodies targeting the extracellular cysteine-rich region of the receptor tyrosine kinase EphB4. Oncotarget. 2015;6:7554-69 pubmed

Bohnekamp J, Cryderman D, Paululat A, Baccam G, Wallrath L, Magin T. A Drosophila Model of Epidermolysis Bullosa Simplex. J Invest Dermatol. 2015;135:2031-2039 pubmed publisher

Tian R, Wang H, Gish G, Petsalaki E, Pasculescu A, Shi Y, et al. Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proc Natl Acad Sci U S A. 2015;112:E1594-603 pubmed publisher

Chu U, Duellman T, Weaver S, Tao Y, Yang J. Endothelial protective genes induced by statin are mimicked by ERK5 activation as triggered by a drug combination of FTI-277 and GGTI-298. Biochim Biophys Acta. 2015;1850:1415-25 pubmed publisher

Kummalue T, Inoue T, Miura Y, Narusawa M, Inoue H, Komatsu N, et al. Ribosomal protein L11- and retinol dehydrogenase 11-induced erythroid proliferation without erythropoietin in UT-7/Epo erythroleukemic cells. Exp Hematol. 2015;43:414-423.e1 pubmed publisher

Manjunath S, Kumar G, Mishra B, Mishra B, Sahoo A, Joshi C, et al. Genomic analysis of host - Peste des petits ruminants vaccine viral transcriptome uncovers transcription factors modulating immune regulatory pathways. Vet Res. 2015;46:15 pubmed publisher

Schmidt A, Lu W, Sindhava V, Huang Y, Burkhardt J, Yang E, et al. Regulatory T cells require TCR signaling for their suppressive function. J Immunol. 2015;194:4362-70 pubmed publisher

Gryshchenko A, Bdzhola V, Balanda A, Briukhovetska N, Kotey I, Golub A, et al. Design, synthesis and biological evaluation of N-phenylthieno[2,3-d]pyrimidin-4-amines as inhibitors of FGFR1. Bioorg Med Chem. 2015;23:2287-93 pubmed publisher

Park J, Hiroshima Y, Lee J, Maawy A, Hoffman R, Bouvet M. MUC1 selectively targets human pancreatic cancer in orthotopic nude mouse models. PLoS ONE. 2015;10:e0122100 pubmed publisher

Schneiders J, Fuchs F, Damm J, Herden C, Gerstberger R, Soares D, et al. The transcription factor nuclear factor interleukin 6 mediates pro- and anti-inflammatory responses during LPS-induced systemic inflammation in mice. Brain Behav Immun. 2015;48:147-64 pubmed publisher

Novak M, Leonard M, Yang X, Kowluru A, Belkin A, Kaetzel D. Metastasis suppressor NME1 regulates melanoma cell morphology, self-adhesion and motility via induction of fibronectin expression. Exp Dermatol. 2015;24:455-61 pubmed publisher

Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed publisher

Abdal Dayem A, Choi H, Kim Y, Cho S. Antiviral effect of methylated flavonol isorhamnetin against influenza. PLoS ONE. 2015;10:e0121610 pubmed publisher

Wu C, Wu H, Wang C, Lin C, Hsu S, Chen Y, et al. Akt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells. Cell Cycle. 2015;14:1207-17 pubmed publisher

Guo C, Hao C, Shao R, Fang B, Correa A, Hofstetter W, et al. RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer. Oncotarget. 2015;6:11114-24 pubmed

Baëhl S, Garneau H, Le Page A, Lorrain D, Viens I, Svotelis A, et al. Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture. Exp Gerontol. 2015;65:58-68 pubmed publisher

Lan X, Wen H, Saleem M, Mikulak J, Malhotra A, Skorecki K, et al. Vascular smooth muscle cells contribute to APOL1-induced podocyte injury in HIV milieu. Exp Mol Pathol. 2015;98:491-501 pubmed publisher

Merckx E, Demuyser T, Bentea E, Van Liefferinge J, Albertini G, Deneyer L, et al. Lack of effect of Theiler's murine encephalomyelitis virus infection on system xc⁻. Neurosci Lett. 2015;593:124-8 pubmed publisher

Petpiroon N, Suktap C, Pongsamart S, Chanvorachote P, Sukrong S. Kaempferol-3-O-rutinoside from Afgekia mahidoliae promotes keratinocyte migration through FAK and Rac1 activation. J Nat Med. 2015;69:340-8 pubmed publisher

Brambilla L, Genini D, Laurini E, Merulla J, Perez L, Fermeglia M, et al. Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3). Mol Oncol. 2015;9:1194-206 pubmed publisher

Nabekura T, Hiroi T, Kawasaki T, Uwai Y. Effects of natural nuclear factor-kappa B inhibitors on anticancer drug efflux transporter human P-glycoprotein. Biomed Pharmacother. 2015;70:140-5 pubmed publisher

Gustafsson A, Abramenkovs A, Stenerlöw B. Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair. Mutat Res. 2014;769:1-10 pubmed publisher

Yamashita H, Yano Y, Kawano K, Matsuzaki K. Oligomerization-function relationship of EGFR on living cells detected by the coiled-coil labeling and FRET microscopy. Biochim Biophys Acta. 2015;1848:1359-66 pubmed publisher

Dos Santos G, Rogel M, Baker M, Troken J, Urich D, Morales Nebreda L, et al. Vimentin regulates activation of the NLRP3 inflammasome. Nat Commun. 2015;6:6574 pubmed publisher

Palei A, Spradley F, Granger J. Chronic hyperleptinemia results in the development of hypertension in pregnant rats. Am J Physiol Regul Integr Comp Physiol. 2015;308:R855-61 pubmed publisher

Choi E, Park C, Shin S, Cho E, Kim B, Hwang J, et al. Zanthoxylum schinifolium leaf ethanol extract inhibits adipocyte differentiation through inactivation of the extracellular signal regulated kinase and phosphoinositide 3-kinase/Akt signaling pathways in 3T3-L1 pre-adipocytes. Mol Med Rep. 2015;12:1314-20 pubmed publisher

Zhao X, Xu Z, Wang Z, Wu Z, Gong Y, Zhou L, et al. RNA silencing of integrin-linked kinase increases the sensitivity of the A549 lung cancer cell line to cisplatin and promotes its apoptosis. Mol Med Rep. 2015;12:960-6 pubmed publisher

Hue C, Cho F, Cao S, Dale Bass C, Meaney D, Morrison B. Dexamethasone potentiates in vitro blood-brain barrier recovery after primary blast injury by glucocorticoid receptor-mediated upregulation of ZO-1 tight junction protein. J Cereb Blood Flow Metab. 2015;35:1191-8 pubmed publisher

Riahi Y, Kaiser N, Cohen G, Abd Elrahman I, Blum G, Shapira O, et al. Foam cell-derived 4-hydroxynonenal induces endothelial cell senescence in a TXNIP-dependent manner. J Cell Mol Med. 2015;19:1887-99 pubmed publisher

Yu H, Zou B, Wang X, Li M. Effect of tyrphostin AG879 on Kv 4.2 and Kv 4.3 potassium channels. Br J Pharmacol. 2015;172:3370-82 pubmed publisher

Olazabal Herrero A, García Santisteban I, Rodríguez J. Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage. Mol Cancer. 2015;14:33 pubmed publisher

Tsuru A, Setoguchi T, Matsunoshita Y, Nagao Kitamoto H, Nagano S, Yokouchi M, et al. Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression. Br J Cancer. 2015;112:1232-40 pubmed publisher

Bouris P, Skandalis S, Piperigkou Z, Afratis N, Karamanou K, Aletras A, et al. Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells. Matrix Biol. 2015;43:42-60 pubmed publisher

Uygur B, Abramo K, Leikina E, Vary C, Liaw L, Wu W. SLUG is a direct transcriptional repressor of PTEN tumor suppressor. Prostate. 2015;75:907-16 pubmed publisher

Aguilar Alonso F, Solano J, Vargas Olvera C, Pacheco Bernal I, Pariente Pérez T, Ibarra Rubio M. MAPKs' status at early stages of renal carcinogenesis and tumors induced by ferric nitrilotriacetate. Mol Cell Biochem. 2015;404:161-70 pubmed publisher

McAdoo S, Bhangal G, Page T, Cook H, Pusey C, Tam F. Correlation of disease activity in proliferative glomerulonephritis with glomerular spleen tyrosine kinase expression. Kidney Int. 2015;88:52-60 pubmed publisher

Ligaba S, Khurana A, Graham G, Krawczyk E, Jablonski S, Petricoin E, et al. Multifactorial analysis of conditional reprogramming of human keratinocytes. PLoS ONE. 2015;10:e0116755 pubmed publisher

Mao F, Xu M, Zuo X, Yu J, Xu W, Moussalli M, et al. 15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway. FASEB J. 2015;29:2359-70 pubmed publisher

Shen J, Yu Q. Gambogic amide selectively upregulates TrkA expression and triggers its activation. Pharmacol Rep. 2015;67:217-23 pubmed publisher

Omori K, Asai M, Kuga D, Ushida K, Izuchi T, Mii S, et al. Girdin is phosphorylated on tyrosine 1798 when associated with structures required for migration. Biochem Biophys Res Commun. 2015;458:934-40 pubmed publisher

Yang Y, Yang Y, Xie X, Wang Z, Gong W, Zhang H, et al. Dual-modified liposomes with a two-photon-sensitive cell penetrating peptide and NGR ligand for siRNA targeting delivery. Biomaterials. 2015;48:84-96 pubmed publisher

Young C, Sinadinos A, Lefebvre A, Chan P, Arkle S, Vaudry D, et al. A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90. Autophagy. 2015;11:113-30 pubmed publisher

Blazquez C, Chiarlone A, Bellocchio L, Resel E, Pruunsild P, García Rincón D, et al. The CB? cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway. Cell Death Differ. 2015;22:1618-29 pubmed publisher

Chaudhuri O, Gu L, Darnell M, Klumpers D, Bencherif S, Weaver J, et al. Substrate stress relaxation regulates cell spreading. Nat Commun. 2015;6:6364 pubmed publisher

Gillen J, Li W, Liang Q, Avey D, Wu J, Wu F, et al. A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses. J Virol. 2015;89:4918-31 pubmed publisher

Wang Y, Chen S, Gao W, Ding J, Shi W, Feng X, et al. Experimental study of survival of pedicled perforator flap with flow-through and flow-end blood supply. Br J Surg. 2015;102:375-81 pubmed publisher

Tancharoen S, Matsuyama T, Kawahara K, Tanaka K, Lee L, Machigashira M, et al. Cleavage of host cytokeratin-6 by lysine-specific gingipain induces gingival inflammation in periodontitis patients. PLoS ONE. 2015;10:e0117775 pubmed publisher

Almeida C, DeMaman A, Kusuda R, Cadetti F, Ravanelli M, Queiroz A, et al. Exercise therapy normalizes BDNF upregulation and glial hyperactivity in a mouse model of neuropathic pain. Pain. 2015;156:504-13 pubmed publisher

Bhardwaj R, Yester J, Singh S, Biswas D, Surace M, Waters M, et al. RelB/p50 complexes regulate cytokine-induced YKL-40 expression. J Immunol. 2015;194:2862-70 pubmed publisher

Kim J, Jin X, Ham S, Lee S, Seo S, Kim S, et al. IRF7 promotes glioma cell invasion by inhibiting AGO2 expression. Tumour Biol. 2015;36:5561-9 pubmed publisher

Harrill J, Robinette B, Freudenrich T, Mundy W. Media formulation influences chemical effects on neuronal growth and morphology. In Vitro Cell Dev Biol Anim. 2015;51:612-29 pubmed publisher

Barbosa B, Lopes Maria J, Gomes A, Angeloni M, Castro A, Franco P, et al. IL10, TGF beta1, and IFN gamma modulate intracellular signaling pathways and cytokine production to control Toxoplasma gondii infection in BeWo trophoblast cells. Biol Reprod. 2015;92:82 pubmed publisher

Kim S, Hyun M, Go K, Zouboulis C, Kim B. Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway. Int J Mol Med. 2015;35:1042-50 pubmed publisher

Gonçalves N, Teixeira Coelho M, Saraiva M. Protective role of anakinra against transthyretin-mediated axonal loss and cell death in a mouse model of familial amyloidotic polyneuropathy. J Neuropathol Exp Neurol. 2015;74:203-17 pubmed publisher

Abella V, Santoro A, Scotece M, Conde J, López López V, Lazzaro V, et al. Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways. Toxicol Lett. 2015;234:13-9 pubmed publisher

Onopiuk M, Brutkowski W, Young C, Krasowska E, Róg J, Ritso M, et al. Store-operated calcium entry contributes to abnormal Ca²⁺ signalling in dystrophic mdx mouse myoblasts. Arch Biochem Biophys. 2015;569:1-9 pubmed publisher

Lütken S, Frøkiær J, Nielsen S. AVP-induced increase in AQP2 and p-AQP2 is blunted in heart failure during cardiac remodeling and is associated with decreased AT1R abundance in rat kidney. PLoS ONE. 2015;10:e0116501 pubmed publisher

Newby E, Kaushal K, Myers D, Ducsay C. Adrenocorticotropic Hormone and PI3K/Akt Inhibition Reduce eNOS Phosphorylation and Increase Cortisol Biosynthesis in Long-Term Hypoxic Ovine Fetal Adrenal Cortical Cells. Reprod Sci. 2015;22:932-41 pubmed publisher

Boriushkin E, Wang J, Li J, Jing G, Seigel G, Zhang S. Identification of p58IPK as a novel neuroprotective factor for retinal neurons. Invest Ophthalmol Vis Sci. 2015;56:1374-86 pubmed publisher

Lv M, Lv M, Chen L, Qin T, Zhang X, Liu P, et al. Angiomotin promotes breast cancer cell proliferation and invasion. Oncol Rep. 2015;33:1938-46 pubmed publisher

Nagy S, Darula Z, Kállai B, Bögre L, Bánhegyi G, Medzihradszky K, et al. Activation of AtMPK9 through autophosphorylation that makes it independent of the canonical MAPK cascades. Biochem J. 2015;467:167-75 pubmed publisher

Augustin E, Skwarska A, Weryszko A, Pelikant I, Sankowska E, Borowa Mazgaj B. The antitumor compound triazoloacridinone C-1305 inhibits FLT3 kinase activity and potentiates apoptosis in mutant FLT3-ITD leukemia cells. Acta Pharmacol Sin. 2015;36:385-99 pubmed publisher

Luu W, Hart Smith G, Sharpe L, Brown A. The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally. J Lipid Res. 2015;56:888-97 pubmed publisher

Do K, Speranza G, Bishop R, Khin S, Rubinstein L, Kinders R, et al. Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer. Invest New Drugs. 2015;33:720-8 pubmed publisher

Castro García P, Díaz Moreno M, Gil Gas C, Fernández Gómez F, Honrubia Gómez P, Álvarez Simón C, et al. Defects in subventricular zone pigmented epithelium-derived factor niche signaling in the senescence-accelerated mouse prone-8. FASEB J. 2015;29:1480-92 pubmed publisher

Eufemi M, Cocchiola R, Romaniello D, Correani V, Di Francesco L, Fabrizi C, et al. Acetylation and phosphorylation of STAT3 are involved in the responsiveness of microglia to beta amyloid. Neurochem Int. 2015;81:48-56 pubmed publisher

Chakraborty S, Lakshmanan M, Swa H, Chen J, Zhang X, Ong Y, et al. An oncogenic role of Agrin in regulating focal adhesion integrity in hepatocellular carcinoma. Nat Commun. 2015;6:6184 pubmed publisher

Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia A, et al. ADAM8 as a drug target in pancreatic cancer. Nat Commun. 2015;6:6175 pubmed publisher

Liang R, Shen X, Zhang B, Li Y, Xu W, Zhao C, et al. Apoptosis signal-regulating kinase 1 promotes Ochratoxin A-induced renal cytotoxicity. Sci Rep. 2015;5:8078 pubmed publisher

Dai X, Ahn K, Kim C, Siveen K, Ong T, Shanmugam M, et al. Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3. Mol Oncol. 2015;9:818-33 pubmed publisher

Steiner J, Lang C. Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction. Alcohol Clin Exp Res. 2015;39:1-10 pubmed publisher

Vochyánová Z, Bartošová L, Bujdáková V, Fictum P, Husník R, Suchý P, et al. Diplacone and mimulone ameliorate dextran sulfate sodium-induced colitis in rats. Fitoterapia. 2015;101:201-7 pubmed publisher

Rao F, Xu J, Fu C, Cha J, Gadalla M, Xu R, et al. Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1. Proc Natl Acad Sci U S A. 2015;112:1773-8 pubmed publisher

Rios F, Neves K, Nguyen Dinh Cat A, Even S, Palacios R, Montezano A, et al. Cholesteryl ester-transfer protein inhibitors stimulate aldosterone biosynthesis in adipocytes through Nox-dependent processes. J Pharmacol Exp Ther. 2015;353:27-34 pubmed publisher

Zuco V, Cassinelli G, Cossa G, Gatti L, Favini E, Tortoreto M, et al. Targeting the invasive phenotype of cisplatin-resistant non-small cell lung cancer cells by a novel histone deacetylase inhibitor. Biochem Pharmacol. 2015;94:79-90 pubmed publisher

Lee G, Yan L, Vatner D, Vatner S. Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis. Basic Res Cardiol. 2015;110:7 pubmed publisher

Rajgopal A, Rebhun J, Burns C, Scholten J, Balles J, Fast D. Immunomodulatory effects of Lippia sidoides extract: induction of IL-10 through cAMP and p38 MAPK-dependent mechanisms. J Med Food. 2015;18:370-7 pubmed publisher

Mandal A, Shahidullah M, Delamere N. Calcium entry via connexin hemichannels in lens epithelium. Exp Eye Res. 2015;132:52-8 pubmed publisher

Tsuboi K, Okamoto Y, Rahman I, Uyama T, Inoue T, Tokumura A, et al. Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis. Biochim Biophys Acta. 2015;1851:537-48 pubmed publisher

Alé A, Bruna J, Herrando M, Navarro X, Udina E. Toxic effects of bortezomib on primary sensory neurons and Schwann cells of adult mice. Neurotox Res. 2015;27:430-40 pubmed publisher

Song E, Oh W, Ulu A, Carr H, Zuo Y, Frost J. Acetylation of the RhoA GEF Net1A controls its subcellular localization and activity. J Cell Sci. 2015;128:913-22 pubmed publisher

Adderley S, Zhang X, Breslin J. Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction. Microcirculation. 2015;22:237-48 pubmed publisher

Tsirmoula S, Lamprou M, Hatziapostolou M, Kieffer N, Papadimitriou E. Pleiotrophin-induced endothelial cell migration is regulated by xanthine oxidase-mediated generation of reactive oxygen species. Microvasc Res. 2015;98:74-81 pubmed publisher

Yue J, Abraham M, Lapierre M, Mighiu P, Light P, Filippi B, et al. A fatty acid-dependent hypothalamic-DVC neurocircuitry that regulates hepatic secretion of triglyceride-rich lipoproteins. Nat Commun. 2015;6:5970 pubmed publisher

Sun R, Wu Y, Wang Y, Zang K, Wei H, Wang F, et al. DNA methylation regulates bromodomain-containing protein 2 expression during adipocyte differentiation. Mol Cell Biochem. 2015;402:23-31 pubmed publisher

Wehinger S, Ortiz R, Díaz M, Aguirre A, Valenzuela M, Llanos P, et al. Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells. Biochim Biophys Acta. 2015;1852:693-708 pubmed publisher

Suwa S, Kasubata A, Kato M, Iida M, Watanabe K, Miura O, et al. The tryptophan derivative, tranilast, and conditioned medium with indoleamine 2,3-dioxygenase-expressing cells inhibit the proliferation of lymphoid malignancies. Int J Oncol. 2015;46:1369-76 pubmed publisher

Zuo J, Guo Y, Peng X, Tang Y, Zhang X, He P, et al. Inhibitory action of pristimerin on hypoxia‑mediated metastasis involves stem cell characteristics and EMT in PC-3 prostate cancer cells. Oncol Rep. 2015;33:1388-94 pubmed publisher

Seto S, Parks A, Qiu Y, Soslowsky L, Karas S, Platt M, et al. Cathepsins in Rotator Cuff Tendinopathy: Identification in Human Chronic Tears and Temporal Induction in a Rat Model. Ann Biomed Eng. 2015;43:2036-46 pubmed publisher

Cohen T, Hwang A, Restrepo C, Yuan C, Trojanowski J, Lee V. An acetylation switch controls TDP-43 function and aggregation propensity. Nat Commun. 2015;6:5845 pubmed publisher

Loría F, Diaz Nido J. Frataxin knockdown in human astrocytes triggers cell death and the release of factors that cause neuronal toxicity. Neurobiol Dis. 2015;76:1-12 pubmed publisher

Nakagawa Y, Gallo R. Endogenous intracellular cathelicidin enhances TLR9 activation in dendritic cells and macrophages. J Immunol. 2015;194:1274-84 pubmed publisher

Bon H, Wadhwa K, Schreiner A, Osborne M, Carroll T, Ramos Montoya A, et al. Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer. Mol Cancer Res. 2015;13:620-635 pubmed publisher

Kremlitzka M, Mácsik Valent B, Erdei A. Syk is indispensable for CpG-induced activation and differentiation of human B cells. Cell Mol Life Sci. 2015;72:2223-36 pubmed publisher

Liu K, Ludgate L, Yuan Z, Hu J. Regulation of multiple stages of hepadnavirus replication by the carboxyl-terminal domain of viral core protein in trans. J Virol. 2015;89:2918-30 pubmed publisher

Cao J, Lin C, Wang H, Wang L, Zhou N, Jin Y, et al. Circovirus transport proceeds via direct interaction of the cytoplasmic dynein IC1 subunit with the viral capsid protein. J Virol. 2015;89:2777-91 pubmed publisher

Lin G, Alwaal A, Sun F, Zhang H, Li H, Wang L, et al. Estrogen attenuates TGF-β1 induced elastogenesis in rat urethral smooth muscle cells by inhibiting Smad response elements. J Urol. 2015;193:2131-7 pubmed publisher

Bellizzi A, Greco M, Rubino R, Paradiso A, Forciniti S, Zeeberg K, et al. The scaffolding protein NHERF1 sensitizes EGFR-dependent tumor growth, motility and invadopodia function to gefitinib treatment in breast cancer cells. Int J Oncol. 2015;46:1214-24 pubmed publisher

Dirat B, Ader I, Golzio M, Massa F, Mettouchi A, Laurent K, et al. Inhibition of the GTPase Rac1 mediates the antimigratory effects of metformin in prostate cancer cells. Mol Cancer Ther. 2015;14:586-96 pubmed publisher

Fang L, Barber A, Shenberger J. Regulation of fibroblast growth factor 2 expression in oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2014;56:207-15 pubmed publisher

Fleetwood F, Klint S, Hanze M, Gunneriusson E, Frejd F, Ståhl S, et al. Simultaneous targeting of two ligand-binding sites on VEGFR2 using biparatopic Affibody molecules results in dramatically improved affinity. Sci Rep. 2014;4:7518 pubmed publisher

Xing S, Zhang C, Yuan J, Yang H, Zhao S, Zhang H. Adiponectin induces apoptosis in hepatocellular carcinoma through differential modulation of thioredoxin proteins. Biochem Pharmacol. 2015;93:221-31 pubmed publisher

Hwang J, Purdy J, Wu K, Rabinowitz J, Shenk T. Estrogen-related receptor α is required for efficient human cytomegalovirus replication. Proc Natl Acad Sci U S A. 2014;111:E5706-15 pubmed publisher

Scudder S, Goo M, Cartier A, Molteni A, Schwarz L, Wright R, et al. Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8. J Neurosci. 2014;34:16637-49 pubmed publisher

Thompson J, Shuttleworth T. Anchoring protein AKAP79-mediated PKA phosphorylation of STIM1 determines selective activation of the ARC channel, a store-independent Orai channel. J Physiol. 2015;593:559-72 pubmed publisher

del Castillo G, Sánchez Blanco E, Martín Villar E, Valbuena Diez A, Langa C, Pérez Gómez E, et al. Soluble endoglin antagonizes Met signaling in spindle carcinoma cells. Carcinogenesis. 2015;36:212-22 pubmed publisher

Maiuthed A, Chanvorachote P. Cisplatin at sub-toxic levels mediates integrin switch in lung cancer cells. Anticancer Res. 2014;34:7111-7 pubmed

Kogita A, Togashi Y, Hayashi H, Banno E, Terashima M, De Velasco M, et al. Activated MET acts as a salvage signal after treatment with alectinib, a selective ALK inhibitor, in ALK-positive non-small cell lung cancer. Int J Oncol. 2015;46:1025-30 pubmed publisher

Günther C, Kind B, Reijns M, Berndt N, Martínez Bueno M, Wolf C, et al. Defective removal of ribonucleotides from DNA promotes systemic autoimmunity. J Clin Invest. 2015;125:413-24 pubmed publisher

Tüzmen M, Yücel N, Kalburcu T, Demiryas N. Effects of curcumin and tannic acid on the aluminum- and lead-induced oxidative neurotoxicity and alterations in NMDA receptors. Toxicol Mech Methods. 2015;25:120-7 pubmed publisher

Hattori H, Janky R, Nietfeld W, Aerts S, Madan Babu M, Venkitaraman A. p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response. Cell Cycle. 2014;13:2572-86 pubmed publisher

Lin X, Xu Q, Veenstra R. Functional formation of heterotypic gap junction channels by connexins-40 and -43. Channels (Austin). 2014;8:433-43 pubmed publisher

Alshaker H, Wang Q, Frampton A, Krell J, Waxman J, Winkler M, et al. Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer. Breast Cancer Res Treat. 2015;149:59-67 pubmed publisher

López Arribillaga E, Rodilla V, Pellegrinet L, Guiu J, Iglesias M, Roman A, et al. Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch. Development. 2015;142:41-50 pubmed publisher

Özlü N, Qureshi M, Toyoda Y, Renard B, Mollaoglu G, Özkan N, et al. Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis. EMBO J. 2015;34:251-65 pubmed publisher

Wellberg E, Rudolph M, Lewis A, Padilla Just N, Jedlicka P, Anderson S. Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasis. Breast Cancer Res. 2014;16:481 pubmed publisher

Cai H, Liu W, Xue Y, Shang X, Liu J, Li Z, et al. Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression. J Neuropathol Exp Neurol. 2015;74:25-37 pubmed publisher

Bender M, Giannini S, Grozovsky R, Jönsson T, Christensen H, Pluthero F, et al. Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice. Blood. 2015;125:1014-24 pubmed publisher

Kwapiszewski R, Kwapiszewska K, Kutter J, Brzozka Z. Three-layer poly(methyl methacrylate) microsystem for analysis of lysosomal enzymes for diagnostic purposes. Anal Chim Acta. 2015;853:702-9 pubmed publisher

Karuppagounder V, Arumugam S, Thandavarayan R, Pitchaimani V, Sreedhar R, Afrin R, et al. Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice. Int Immunopharmacol. 2014;23:617-23 pubmed

Yamaguchi T, Izumi Y, Nakamura Y, Yamazaki T, Shiota M, Sano S, et al. Repeated remote ischemic conditioning attenuates left ventricular remodeling via exosome-mediated intercellular communication on chronic heart failure after myocardial infarction. Int J Cardiol. 2015;178:239-46 pubmed publisher

Kettenbach A, Sano H, Keller S, Lienhard G, Gerber S. SPECHT - single-stage phosphopeptide enrichment and stable-isotope chemical tagging: quantitative phosphoproteomics of insulin action in muscle. J Proteomics. 2015;114:48-60 pubmed publisher

Na S, Aldonza M, Sung H, Kim Y, Son Y, Cho S, et al. Stanniocalcin-2 (STC2): A potential lung cancer biomarker promotes lung cancer metastasis and progression. Biochim Biophys Acta. 2015;1854:668-76 pubmed publisher

Lucena M, Pinto M, Garçon D, McNamara J, Leone F. A kinetic characterization of the gill V(H(+))-ATPase in juvenile and adult Macrobrachium amazonicum, a diadromous palaemonid shrimp. Comp Biochem Physiol B Biochem Mol Biol. 2015;181:15-25 pubmed publisher

Stelzhammer V, Alsaif M, Chan M, Rahmoune H, Steeb H, Guest P, et al. Distinct proteomic profiles in post-mortem pituitary glands from bipolar disorder and major depressive disorder patients. J Psychiatr Res. 2015;60:40-8 pubmed publisher

Lee M, Bingham K, Mitchell T, Meredith J, Rawlings J. Calcium mobilization is both required and sufficient for initiating chromatin decondensation during activation of peripheral T-cells. Mol Immunol. 2015;63:540-9 pubmed publisher

Healy M, Chow J, Byrne F, Breen D, Leitinger N, Li C, et al. Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine. J Hepatol. 2015;62:599-606 pubmed publisher

Delint Ramirez I, Maldonado Ruiz R, Torre Villalvazo I, Fuentes Mera L, Garza Ocañas L, Tovar A, et al. Genetic obesity alters recruitment of TANK-binding kinase 1 and AKT into hypothalamic lipid rafts domains. Neurochem Int. 2015;80:23-32 pubmed publisher

Miki A, Kanamori A, Nakamura M, Matsumoto Y, Mizokami J, Negi A. The expression of syntaphilin is down-regulated in the optic nerve after axonal injury. Exp Eye Res. 2014;129:38-47 pubmed publisher

Kim Y, Bahn M, Kim Y, Shin J, Cheong S, Ju B, et al. Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites. Dev Biol. 2015;397:129-39 pubmed publisher

Greenshields A, Doucette C, Sutton K, Madera L, Annan H, Yaffe P, et al. Piperine inhibits the growth and motility of triple-negative breast cancer cells. Cancer Lett. 2015;357:129-40 pubmed publisher

Jilani Y, Lu S, Lei H, Karnitz L, Chadli A. UNC45A localizes to centrosomes and regulates cancer cell proliferation through ChK1 activation. Cancer Lett. 2015;357:114-20 pubmed publisher

Kunath T, Yamanaka Y, Detmar J, MacPhee D, Caniggia I, Rossant J, et al. Developmental differences in the expression of FGF receptors between human and mouse embryos. Placenta. 2014;35:1079-88 pubmed publisher

Morgan Bathke M, Harris Z, Arnett D, Klein R, Burd R, Ann D, et al. The Rapalogue, CCI-779, improves salivary gland function following radiation. PLoS ONE. 2014;9:e113183 pubmed publisher

Onnureddy K, Ravinder -, Onteru S, Singh D. IGF-1 attenuates LPS induced pro-inflammatory cytokines expression in buffalo (Bubalus bubalis) granulosa cells. Mol Immunol. 2015;64:136-43 pubmed publisher

Monsey M, Gerhard D, Boyle L, Briones M, Seligsohn M, Schafe G. A diet enriched with curcumin impairs newly acquired and reactivated fear memories. Neuropsychopharmacology. 2015;40:1278-88 pubmed publisher

Liu G, Honisch S, Liu G, Schmidt S, Pantelakos S, Alkahtani S, et al. Inhibition of SGK1 enhances mAR-induced apoptosis in MCF-7 breast cancer cells. Cancer Biol Ther. 2015;16:52-9 pubmed publisher

Steiner J, Lang C. Sepsis attenuates the anabolic response to skeletal muscle contraction. Shock. 2015;43:344-51 pubmed publisher

Henze A, Garvalov B, Seidel S, Cuesta A, Ritter M, Filatova A, et al. Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nat Commun. 2014;5:5582 pubmed publisher

Garvalov B, Foss F, Henze A, Bethani I, Gräf Höchst S, Singh D, et al. PHD3 regulates EGFR internalization and signalling in tumours. Nat Commun. 2014;5:5577 pubmed publisher

Sylow L, Møller L, Kleinert M, Richter E, Jensen T. Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1. J Physiol. 2015;593:645-56 pubmed publisher

Jiang L, Campagne C, Sundström E, Sousa P, Imran S, Seltenhammer M, et al. Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses. BMC Cancer. 2014;14:857 pubmed publisher

Saitoh S, Mori A, Uehara L, Masuda F, Soejima S, Yanagida M. Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR. Mol Biol Cell. 2015;26:373-86 pubmed publisher

Fan G, Wrzeszczynski K, Fu C, Su G, Pappin D, Lucito R, et al. A quantitative proteomics-based signature of platinum sensitivity in ovarian cancer cell lines. Biochem J. 2015;465:433-42 pubmed publisher

Fernandes R, Bento C, Matafome P, Sena C, Seiça R, Pereira P. Atorvastatin-mediated protection of the retina in a model of diabetes with hyperlipidemia. Can J Physiol Pharmacol. 2014;92:1037-43 pubmed publisher

Landon A, Muniandy P, Shetty A, Lehrmann E, Volpon L, Houng S, et al. MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL. Nat Commun. 2014;5:5413 pubmed publisher

Hancox U, Cosulich S, Hanson L, Trigwell C, Lenaghan C, Ellston R, et al. Inhibition of PI3Kβ signaling with AZD8186 inhibits growth of PTEN-deficient breast and prostate tumors alone and in combination with docetaxel. Mol Cancer Ther. 2015;14:48-58 pubmed publisher

Park J, Pyee J, Park H. Pinosylvin at a high concentration induces AMPK-mediated autophagy for preventing necrosis in bovine aortic endothelial cells. Can J Physiol Pharmacol. 2014;92:993-9 pubmed publisher

Shriver M, Stroka K, Vitolo M, Martin S, Huso D, Konstantopoulos K, et al. Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis. Oncogene. 2015;34:4248-59 pubmed publisher

Yi P, Chew L, Zhang Z, Ren H, Wang F, Cong X, et al. KIF5B transports BNIP-2 to regulate p38 mitogen-activated protein kinase activation and myoblast differentiation. Mol Biol Cell. 2015;26:29-42 pubmed publisher

Yu X, Long Y. Autophagy modulates amino acid signaling network in myotubes: differential effects on mTORC1 pathway and the integrated stress response. FASEB J. 2015;29:394-407 pubmed publisher

Xiao Y, Wang S. Differentiation of Schwann‑like cells from human umbilical cord blood mesenchymal stem cells in vitro. Mol Med Rep. 2015;11:1146-52 pubmed publisher

Luo L, Kim E, Cheung H, Weir B, Dunn G, Shen R, et al. The Tyrosine Kinase Adaptor Protein FRS2 Is Oncogenic and Amplified in High-Grade Serous Ovarian Cancer. Mol Cancer Res. 2015;13:502-9 pubmed publisher

Shimada S, Fukai M, Wakayama K, Ishikawa T, Kobayashi N, Kimura T, et al. Hydrogen sulfide augments survival signals in warm ischemia and reperfusion of the mouse liver. Surg Today. 2015;45:892-903 pubmed publisher

Gritti M, Würth R, Angelini M, Barbieri F, Peretti M, Pizzi E, et al. Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current. Oncotarget. 2014;5:11252-68 pubmed

Tang J, Wang G, Zhang M, Li F, Sang Y, Wang B, et al. Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer. Oncotarget. 2014;5:10778-90 pubmed

Chen K, Bai H, Liu Y, Hoyle D, Shen W, Wu L, et al. EphB4 forward-signaling regulates cardiac progenitor development in mouse ES cells. J Cell Biochem. 2015;116:467-75 pubmed publisher

Ferrari de Andrade L, Ngiow S, Stannard K, Rusakiewicz S, Kalimutho M, Khanna K, et al. Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma. Cancer Res. 2014;74:7298-308 pubmed publisher

Clayton N, Nelson C, Weeden T, Taylor K, Moreland R, Scheule R, et al. Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease. Mol Ther Nucleic Acids. 2014;3:e206 pubmed publisher

Mu G, Zhang L, Li H, Liao Y, Yu H. Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer. Dig Dis Sci. 2015;60:1067-80 pubmed publisher

Ju J, Oh S, Lee K, Yang W, Nam K, Moon H, et al. Cytokeratin19 induced by HER2/ERK binds and stabilizes HER2 on cell membranes. Cell Death Differ. 2015;22:665-76 pubmed publisher

Petridou N, Skourides P. FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis. Nat Commun. 2014;5:5240 pubmed publisher

Gallot Y, Durieux A, Castells J, Desgeorges M, Vernus B, Plantureux L, et al. Myostatin gene inactivation prevents skeletal muscle wasting in cancer. Cancer Res. 2014;74:7344-56 pubmed publisher

Khodabukus A, Baar K. Contractile and metabolic properties of engineered skeletal muscle derived from slow and fast phenotype mouse muscle. J Cell Physiol. 2015;230:1750-7 pubmed publisher

Lou J, Low Nam S, Kerkvliet J, Hoppe A. Delivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages. J Cell Sci. 2014;127:5228-39 pubmed publisher

Vančo J, Gáliková J, Hosek J, Dvorak Z, Paráková L, Trávníček Z. Gold(I) complexes of 9-deazahypoxanthine as selective antitumor and anti-inflammatory agents. PLoS ONE. 2014;9:e109901 pubmed publisher

Chen X, Xie X, Zhao Q, Wang F, Bai Y, Yin J, et al. Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells. Mol Med Rep. 2015;11:105-12 pubmed publisher

Huber R, Myre M, Cotman S. Loss of Cln3 function in the social amoeba Dictyostelium discoideum causes pleiotropic effects that are rescued by human CLN3. PLoS ONE. 2014;9:e110544 pubmed publisher

Chen C, Song X, Ma S, Wang X, Xu J, Zhang H, et al. Cdc42 inhibitor ML141 enhances G-CSF-induced hematopoietic stem and progenitor cell mobilization. Int J Hematol. 2015;101:5-12 pubmed publisher

Zhu J, Zhang X, Li L, Su G. Protective effects of epigallocatechin-3 gallate on atrial electrical and structural remodeling in a rabbit rapid atrial pacing model. Cell Biochem Biophys. 2015;71:897-903 pubmed publisher

St Germain J, Taylor P, Zhang W, Li Z, Ketela T, Moffat J, et al. Differential regulation of FGFR3 by PTPN1 and PTPN2. Proteomics. 2015;15:419-33 pubmed publisher

Goren I, Pfeilschifter J, Frank S. Uptake of neutrophil-derived Ym1 protein distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing. Am J Pathol. 2014;184:3249-61 pubmed publisher

Zhang W, Li H, Yang Y, Liao J, Yang G. Knockdown or inhibition of aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras-E-cadherin pathway. Cancer Lett. 2014;355:273-80 pubmed publisher

Toniolo A, Fadini G, Tedesco S, Cappellari R, Vegeto E, Maggi A, et al. Alternative activation of human macrophages is rescued by estrogen treatment in vitro and impaired by menopausal status. J Clin Endocrinol Metab. 2015;100:E50-8 pubmed publisher

Gwak H, Park M, Park I, Woo S, Jin H, Rhee C, et al. Tetraarsenic oxide-induced inhibition of malignant glioma cell invasion in vitro via a decrease in matrix metalloproteinase secretion and protein kinase B phosphorylation. J Neurosurg. 2014;121:1483-91 pubmed publisher

Chen W, Yeap Y, Bogoyevitch M. The JNK1/JNK3 interactome--contributions by the JNK3 unique N-terminus and JNK common docking site residues. Biochem Biophys Res Commun. 2014;453:576-81 pubmed publisher

Uemura Y, Shibata R, Kanemura N, Ohashi K, Kambara T, Hiramatsu Ito M, et al. Adipose-derived protein omentin prevents neointimal formation after arterial injury. FASEB J. 2015;29:141-51 pubmed publisher

Liu H, Wang T, Li Q, Guan X, Xu Q. Knock-down of p300 decreases the proliferation and odontogenic differentiation potentiality of HDPCs. Int Endod J. 2015;48:976-85 pubmed publisher

Nordströma U, Beauvais G, Ghosh A, Pulikkaparambil Sasidharan B, Lundblad M, Fuchs J, et al. Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease. Neurobiol Dis. 2015;73:70-82 pubmed publisher

Kaliyaperumal A, Pennucci J, Nagatani J, Juan G, Swanson S, Gupta S. A method to quantitate the neutralizing capacity of anti-therapeutic protein antibodies in serum and their correlation to clinical impact. J Pharm Biomed Anal. 2015;102:176-83 pubmed publisher

Anitei M, Chenna R, Czupalla C, Esner M, Christ S, Lenhard S, et al. A high-throughput siRNA screen identifies genes that regulate mannose 6-phosphate receptor trafficking. J Cell Sci. 2014;127:5079-92 pubmed publisher

Dielschneider R, Xiao W, Yoon J, Noh E, Banerji V, Li H, et al. Gefitinib targets ZAP-70-expressing chronic lymphocytic leukemia cells and inhibits B-cell receptor signaling. Cell Death Dis. 2014;5:e1439 pubmed publisher

Rajan V, Tripathi J, Variyar P, Pandey B. Mechanism of cytotoxicity by Psoralea corylifolia extract in human breast carcinoma cells. J Environ Pathol Toxicol Oncol. 2014;33:265-77 pubmed

Chmielecki J, Hutchinson K, Frampton G, Chalmers Z, Johnson A, Shi C, et al. Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes. Cancer Discov. 2014;4:1398-405 pubmed publisher

Kang Y, Ling J, Suzuki R, Roife D, Chopin Laly X, Truty M, et al. SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium. PLoS ONE. 2014;9:e107948 pubmed publisher

Cejudo Martin P, Yuen A, Vlahovich N, Lock P, Courtneidge S, Diaz B. Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5. PLoS ONE. 2014;9:e107674 pubmed publisher

Maggioni D, Nicolini G, Rigolio R, Biffi L, Pignataro L, Gaini R, et al. Myricetin and naringenin inhibit human squamous cell carcinoma proliferation and migration in vitro. Nutr Cancer. 2014;66:1257-67 pubmed publisher

Chadt A, Immisch A, de Wendt C, Springer C, Zhou Z, Stermann T, et al. “Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected]. Diabetes. 2015;64:746-59 pubmed publisher

Poli M, Asperti M, Ruzzenenti P, Mandelli L, Campostrini N, Martini G, et al. Oversulfated heparins with low anticoagulant activity are strong and fast inhibitors of hepcidin expression in vitro and in vivo. Biochem Pharmacol. 2014;92:467-75 pubmed publisher

Roberto V, Tiago D, Silva I, Cancela M. MiR-29a is an enhancer of mineral deposition in bone-derived systems. Arch Biochem Biophys. 2014;564:173-83 pubmed publisher

Sadi G, Ergin V, Yilmaz G, Pektas M, Yildirim O, Menevse A, et al. High-fructose corn syrup-induced hepatic dysfunction in rats: improving effect of resveratrol. Eur J Nutr. 2015;54:895-904 pubmed publisher

Rakesh K, Jagadish S, Vinayaka A, Hemshekhar M, Paul M, Thushara R, et al. A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis. PLoS ONE. 2014;9:e107182 pubmed publisher

Johnson J, Dia V, Wallig M, Gonzalez de Mejia E. Luteolin and Gemcitabine Protect Against Pancreatic Cancer in an Orthotopic Mouse Model. Pancreas. 2015;44:144-51 pubmed publisher

Saran V, Sharma V, Wambolt R, Yuen V, Allard M, McNeill J. Combined metoprolol and ascorbic acid treatment prevents intrinsic damage to the heart during diabetic cardiomyopathy. Can J Physiol Pharmacol. 2014;92:827-37 pubmed publisher

Gerarduzzi C, He Q, Antoniou J, Di Battista J. Quantitative phosphoproteomic analysis of signaling downstream of the prostaglandin e2/g-protein coupled receptor in human synovial fibroblasts: potential antifibrotic networks. J Proteome Res. 2014;13:5262-80 pubmed publisher

De Amicis F, Guido C, Santoro M, Lanzino M, Panza S, Avena P, et al. A novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells. J Cell Mol Med. 2014;18:2252-65 pubmed publisher

Scuderi C, Stecca C, Valenza M, Ratano P, Bronzuoli M, Bartoli S, et al. Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer's disease. Cell Death Dis. 2014;5:e1419 pubmed publisher

Walsh M, Pearce E, Cejas P, Lee J, Wang L, Choi Y. IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals. J Immunol. 2014;193:3992-4001 pubmed publisher

Chen X, Shi X, Zhao C, Li X, Lan X, Liu S, et al. Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms. Oncotarget. 2014;5:9118-32 pubmed

Zieger M, Ahnelt P, Uhrin P. CX3CL1 (fractalkine) protein expression in normal and degenerating mouse retina: in vivo studies. PLoS ONE. 2014;9:e106562 pubmed publisher

Mitić T, Caporali A, Floris I, Meloni M, Marchetti M, Urrutia R, et al. EZH2 modulates angiogenesis in vitro and in a mouse model of limb ischemia. Mol Ther. 2015;23:32-42 pubmed publisher

Perfetto B, Filosa R, De Gregorio V, Peduto A, La Gatta A, de Caprariis P, et al. In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat). J Med Microbiol. 2014;63:1474-1483 pubmed publisher

Palazuelos J, Crawford H, Klingener M, Sun B, Karelis J, Raines E, et al. TACE/ADAM17 is essential for oligodendrocyte development and CNS myelination. J Neurosci. 2014;34:11884-96 pubmed publisher

Esteras N, Alquézar C, Bartolomé F, de la Encarnación A, Bermejo Pareja F, Molina J, et al. G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients. Mol Neurobiol. 2015;52:386-98 pubmed publisher

Zhou D, Cui Y, Xiao P, Jiang M, Han B. A general and scalable synthesis approach to porous graphene. Nat Commun. 2014;5:4716 pubmed publisher

Loinard C, Basatemur G, Masters L, Baker L, Harrison J, Figg N, et al. Deletion of chromosome 9p21 noncoding cardiovascular risk interval in mice alters Smad2 signaling and promotes vascular aneurysm. Circ Cardiovasc Genet. 2014;7:799-805 pubmed publisher

Zhou L, Wang Z, Lian H, Song H, Zhang Y, Zhang X, et al. Altered expression of dopamine receptors in cholinergic motoneurons of the hypoglossal nucleus in a 6-OHDA-induced Parkinson's disease rat model. Biochem Biophys Res Commun. 2014;452:560-6 pubmed publisher

Guelzim N, Huneau J, Mathé V, Tesseraud S, Mourot J, Simon N, et al. N-3 fatty acids improve body composition and insulin sensitivity during energy restriction in the rat. Prostaglandins Leukot Essent Fatty Acids. 2014;91:203-11 pubmed publisher

Asnaghi L, Lin M, Lim K, Lim K, Tripathy A, Wendeborn M, et al. Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation. PLoS ONE. 2014;9:e105372 pubmed publisher

Pérez S, Pereda J, Sabater L, Sastre J. Pancreatic ascites hemoglobin contributes to the systemic response in acute pancreatitis. Free Radic Biol Med. 2015;81:145-55 pubmed publisher

Szczęsny E, Basta Kaim A, Slusarczyk J, Trojan E, Glombik K, Regulska M, et al. The impact of prenatal stress on insulin-like growth factor-1 and pro-inflammatory cytokine expression in the brains of adult male rats: the possible role of suppressors of cytokine signaling proteins. J Neuroimmunol. 2014;276:37-46 pubmed publisher

Finnen R, Hay T, Dauber B, Smiley J, Banfield B. The herpes simplex virus 2 virion-associated ribonuclease vhs interferes with stress granule formation. J Virol. 2014;88:12727-39 pubmed publisher

Terashima M, Sakai K, Togashi Y, Hayashi H, De Velasco M, Tsurutani J, et al. Synergistic antitumor effects of S-1 with eribulin in vitro and in vivo for triple-negative breast cancer cell lines. Springerplus. 2014;3:417 pubmed publisher

Arruda Barbosa L, Rodrigues K, Souza Neto F, Duarte G, Borges R, Magalhães P, et al. Vasorelaxant effects of 1-nitro-2-phenylethene in rat isolated aortic rings. Vascul Pharmacol. 2014;63:55-62 pubmed publisher

Pfisterer K, Forster F, Paster W, Supper V, Ohradanova Repic A, Eckerstorfer P, et al. The late endosomal transporter CD222 directs the spatial distribution and activity of Lck. J Immunol. 2014;193:2718-32 pubmed publisher

Swa H, Shaik A, Lim L, Gunaratne J. Mass spectrometry based quantitative proteomics and integrative network analysis accentuates modulating roles of annexin-1 in mammary tumorigenesis. Proteomics. 2015;15:408-18 pubmed publisher

Vasconcelos Silva A, Lima F, Brito T, Lahlou S, Magalhães P. Vasorelaxation induced by methyl cinnamate, the major constituent of the essential oil of Ocimum micranthum, in rat isolated aorta. Clin Exp Pharmacol Physiol. 2014;41:755-62 pubmed publisher

Frullini A, Da Pozzo E, Felice F, Burchielli S, Martini C, Di Stefano R. Prevention of excessive endothelin-1 release in sclerotherapy: in vitro and in vivo studies. Dermatol Surg. 2014;40:769-75 pubmed publisher

Su C, Chan C, Chen H, Wu C, Hsiao C, Lee P, et al. Lutein inhibits the migration of retinal pigment epithelial cells via cytosolic and mitochondrial Akt pathways (lutein inhibits RPE cells migration). Int J Mol Sci. 2014;15:13755-67 pubmed publisher

Nagappan A, Varghese J, Pranesh G, Jeyaseelan V, Jacob M. Indomethacin inhibits activation of endothelial nitric oxide synthase in the rat kidney: possible role of this effect in the pathogenesis of indomethacin-induced renal damage. Chem Biol Interact. 2014;221:77-87 pubmed publisher

Watnick R, Rodriguez R, Wang S, Blois A, Rangarajan A, Ince T, et al. Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells. Oncogene. 2015;34:2823-35 pubmed publisher

Ueki T, Uwagaki M, Yamamoto S, Michibata H. Participation of thioredoxin in the V(V)-reduction reaction by Vanabin2. Biochim Biophys Acta. 2014;1840:3238-45 pubmed publisher

Mladenović D, Hrnčić D, Petronijević N, Jevtić G, Radosavljević T, Rašić Marković A, et al. Finasteride improves motor, EEG, and cellular changes in rat brain in thioacetamide-induced hepatic encephalopathy. Am J Physiol Gastrointest Liver Physiol. 2014;307:G931-40 pubmed publisher

Lin G, LaPensee C, Qin Z, Schwartz J. Reciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3. Mol Cell Endocrinol. 2014;395:19-31 pubmed publisher

Lööv C, Nadadhur A, Hillered L, Clausen F, Erlandsson A. Extracellular ezrin: a novel biomarker for traumatic brain injury. J Neurotrauma. 2015;32:244-51 pubmed publisher

Sha L, Dong L, Lv L, Bai L, Ji X. HOXB9 promotes epithelial-to-mesenchymal transition via transforming growth factor-?1 pathway in hepatocellular carcinoma cells. Clin Exp Med. 2015;15:55-64 pubmed publisher

Li Y, Zhang B, Huang K, He X, Luo Y, Liang R, et al. Mitochondrial proteomic analysis reveals the molecular mechanisms underlying reproductive toxicity of zearalenone in MLTC-1 cells. Toxicology. 2014;324:55-67 pubmed publisher

Hamatani H, Hiromura K, Sakairi T, Takahashi S, Watanabe M, Maeshima A, et al. Expression of a novel stress-inducible protein, sestrin 2, in rat glomerular parietal epithelial cells. Am J Physiol Renal Physiol. 2014;307:F708-17 pubmed publisher

Hamouda M, Belhacene N, Puissant A, Colosetti P, Robert G, Jacquel A, et al. The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells. Oncotarget. 2014;5:6252-66 pubmed

Jayanthan A, Ruan Y, Truong T, Narendran A. Aurora kinases as druggable targets in pediatric leukemia: heterogeneity in target modulation activities and cytotoxicity by diverse novel therapeutic agents. PLoS ONE. 2014;9:e102741 pubmed publisher

Pathania D, Kuang Y, Sechi M, Neamati N. Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells. Br J Pharmacol. 2015;172:50-63 pubmed publisher

Ferry A, Joanne P, Hadj Saïd W, Vignaud A, Lilienbaum A, Hourde C, et al. Advances in the understanding of skeletal muscle weakness in murine models of diseases affecting nerve-evoked muscle activity, motor neurons, synapses and myofibers. Neuromuscul Disord. 2014;24:960-72 pubmed publisher

Fernández Barral A, Orgaz J, Baquero P, Ali Z, Moreno A, Tiana M, et al. Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma. Neoplasia. 2014;16:529-42 pubmed publisher

Bainbridge T, DeAlmeida V, Izrael Tomasevic A, Chalouni C, Pan B, Goldsmith J, et al. Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains. PLoS ONE. 2014;9:e102695 pubmed publisher

Wang C, Hsiao C, Lin Y, Wu J, Kuo Y, Lee C, et al. Carbamazepine attenuates inducible nitric oxide synthase expression through Akt inhibition in activated microglial cells. Pharm Biol. 2014;52:1451-9 pubmed publisher

Misra S, Ghatak S, Vyas A, O Brien P, Markwald R, Khetmalas M, et al. Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer. Med Chem Res. 2014;23:3836-3851 pubmed

Moreno E, Doughty Shenton D, Plano D, Font M, Encio I, Palop J, et al. A dihydroselenoquinazoline inhibits S6 ribosomal protein signalling, induces apoptosis and inhibits autophagy in MCF-7 cells. Eur J Pharm Sci. 2014;63:87-95 pubmed publisher

Hsu J, Liu S, Lee C, Hsu L, Ho Y, Huang H, et al. A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2014;387:979-90 pubmed publisher

Heck N, Dos Santos M, Amairi B, Salery M, Besnard A, Herzog E, et al. A new automated 3D detection of synaptic contacts reveals the formation of cortico-striatal synapses upon cocaine treatment in vivo. Brain Struct Funct. 2015;220:2953-66 pubmed publisher

Uriostegui Acosta M, Hernandez Ochoa I, Sánchez Gutiérrez M, Piña Guzmán B, Rafael Vázquez L, Solís Heredia M, et al. Methamidophos alters sperm function and DNA at different stages of spermatogenesis in mice. Toxicol Appl Pharmacol. 2014;279:391-400 pubmed publisher

Schlager M, Hoang H, Urnavicius L, Bullock S, Carter A. In vitro reconstitution of a highly processive recombinant human dynein complex. EMBO J. 2014;33:1855-68 pubmed publisher

Dewi N, Yagasaki K, Miura Y. Anti-proliferative effect of pterostilbene on rat hepatoma cells in culture. Cytotechnology. 2015;67:671-80 pubmed publisher

Liu N, Li X, Huang H, Zhao C, Liao S, Yang C, et al. Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth. Oncotarget. 2014;5:5453-71 pubmed

Tian A, Wilson G, Lie S, Wu G, Hu Z, Hebbard L, et al. Synergistic effects of IAP inhibitor LCL161 and paclitaxel on hepatocellular carcinoma cells. Cancer Lett. 2014;351:232-41 pubmed publisher

Panigrahi G, Yadav A, Yadav A, Ansari K, Chaturvedi R, Vashistha V, et al. Hepatic transcriptional analysis in rats treated with Cassia occidentalis seed: involvement of oxidative stress and impairment in xenobiotic metabolism as a putative mechanism of toxicity. Toxicol Lett. 2014;229:273-83 pubmed publisher

Chao M, Erkekoglu P, Tseng C, Ye W, Trudel L, Skipper P, et al. Intracellular generation of ROS by 3,5-dimethylaminophenol: persistence, cellular response, and impact of molecular toxicity. Toxicol Sci. 2014;141:300-13 pubmed publisher

Varga J, Bátor J, Péter M, Árvai Z, Pap M, Setalo G, et al. The role of the p53 protein in nitrosative stress-induced apoptosis of PC12 rat pheochromocytoma cells. Cell Tissue Res. 2014;358:65-74 pubmed publisher

Choi W, Park M, Park K, Courneya J, Cho J, Schon L, et al. Comparative analysis of gene expression in normal and degenerative human tendon cells: effects of cyclic strain. Foot Ankle Int. 2014;35:1045-56 pubmed publisher

Guo X, Tian X, Ruan Z, Chen Y, Wu L, Gong Q, et al. Dysregulation of neurotrophic and inflammatory systems accompanied by decreased CREB signaling in ischemic rat retina. Exp Eye Res. 2014;125:156-63 pubmed publisher

Porlan E, Martí Prado B, Morante Redolat J, Consiglio A, Delgado A, Kypta R, et al. MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin. Nat Cell Biol. 2014;16:629-38 pubmed publisher

Hsu P, Yang F, Smith Kinnaman W, Yang W, Song J, Mosley A, et al. Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA polymerase II CTD. J Mol Biol. 2014;426:2970-81 pubmed publisher

Gryshchenko A, Levchenko K, Bdzhola V, Ruban T, Lukash L, Yarmoluk S. Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors. J Enzyme Inhib Med Chem. 2015;30:126-32 pubmed publisher

Carvajal R, Sosman J, Quevedo J, Milhem M, Joshua A, Kudchadkar R, et al. Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial. JAMA. 2014;311:2397-405 pubmed publisher

Jones D, Keune W, Anderson K, Stephens L, Hawkins P, Divecha N. The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation. FEBS J. 2014;281:3591-608 pubmed publisher

Wang Y, Kathawala R, Zhang Y, Patel A, Kumar P, Shukla S, et al. Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1. Biochem Pharmacol. 2014;90:367-78 pubmed publisher

Wang H, Chiang W, Huang H, Shen Y, Chiang H. Src-homology 2 domain-containing tyrosine phosphatase 2 promotes oral cancer invasion and metastasis. BMC Cancer. 2014;14:442 pubmed publisher

Segvić Klarić M, Medić N, Hulina A, Zanić Grubisić T, Rumora L. Disturbed Hsp70 and Hsp27 expression and thiol redox status in porcine kidney PK15 cells provoked by individual and combined ochratoxin A and citrinin treatments. Food Chem Toxicol. 2014;71:97-105 pubmed publisher

Frietsch J, Kastner C, Grunewald T, Schweigel H, Nollau P, Ziermann J, et al. LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia. Oncotarget. 2014;5:5257-71 pubmed

Napolitano M, Comegna M, Succoio M, Leggiero E, Pastore L, Faraonio R, et al. Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs. PLoS ONE. 2014;9:e98669 pubmed publisher

BuÅ‚dak Å, Łabuzek K, BuÅ‚dak R, KozÅ‚owski M, Machnik G, Liber S, et al. Metformin affects macrophages' phenotype and improves the activity of glutathione peroxidase, superoxide dismutase, catalase and decreases malondialdehyde concentration in a partially AMPK-independent manner in LPS-stimulated human monocytes/macropha. Pharmacol Rep. 2014;66:418-29 pubmed publisher

Zelnikar M, Bencina M, Jerala R, Mancek Keber M. Vanadate from air pollutant inhibits hrs-dependent endosome fusion and augments responsiveness to toll-like receptors. PLoS ONE. 2014;9:e99287 pubmed publisher

Lund D, Mouly V, Cornelison D. MMP-14 is necessary but not sufficient for invasion of three-dimensional collagen by human muscle satellite cells. Am J Physiol Cell Physiol. 2014;307:C140-9 pubmed publisher

LaPensee C, Lin G, Dent A, Schwartz J. Deficiency of the transcriptional repressor B cell lymphoma 6 (Bcl6) is accompanied by dysregulated lipid metabolism. PLoS ONE. 2014;9:e97090 pubmed publisher

Francavilla A, Pesetti B, Barone M, Morgano A, Bovenga F, Napoli A, et al. Transient GFER knockdown in vivo impairs liver regeneration after partial hepatectomy. Int J Biochem Cell Biol. 2014;53:343-51 pubmed publisher

Matteucci A, Gaddini L, Villa M, Varano M, Parravano M, Monteleone V, et al. Neuroprotection by rat Müller glia against high glucose-induced neurodegeneration through a mechanism involving ERK1/2 activation. Exp Eye Res. 2014;125:20-9 pubmed publisher

Yamane K, Indalao I, Chida J, Yamamoto Y, Hanawa M, Kido H. Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza. PLoS ONE. 2014;9:e98032 pubmed publisher

Appolloni I, Barilari M, Caviglia S, Gambini E, Reisoli E, Malatesta P. A cadherin switch underlies malignancy in high-grade gliomas. Oncogene. 2015;34:1991-2002 pubmed publisher

Yu K, Wang Y, Wang L, Jian Y, Zhao X, Chen J, et al. Mitochondrial KATP channel involvement in angiotensin II-induced autophagy in vascular smooth muscle cells. Basic Res Cardiol. 2014;109:416 pubmed publisher

Gandhi R, Yi J, Ha J, Shi H, Ismail O, Nathoo S, et al. Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis. Am J Physiol Renal Physiol. 2014;307:F205-21 pubmed publisher

Li H, Hui X, Li K, Tang X, Hu X, Xu A, et al. High-level expression, purification and characterization of active human C1q and tumour necrosis factor-related protein-1 in Escherichia coli. Lett Appl Microbiol. 2014;59:334-41 pubmed publisher

Batson J, MacCarthy Morrogh L, Archer A, Tanton H, Nobes C. EphA receptors regulate prostate cancer cell dissemination through Vav2-RhoA mediated cell-cell repulsion. Biol Open. 2014;3:453-62 pubmed publisher

Remant B, Chandrashekaran V, Cheng B, Chen H, Pena M, Zhang J, et al. Redox potential ultrasensitive nanoparticle for the targeted delivery of camptothecin to HER2-positive cancer cells. Mol Pharm. 2014;11:1897-905 pubmed publisher

Gupta M, Qi X, Thakur V, Manor D. Tyrosine phosphorylation of Dbl regulates GTPase signaling. J Biol Chem. 2014;289:17195-202 pubmed publisher

Stragier E, Massart R, Saléry M, Hamon M, Geny D, Martin V, et al. Ethanol-induced epigenetic regulations at the Bdnf gene in C57BL/6J mice. Mol Psychiatry. 2015;20:405-12 pubmed publisher

Rial D, Pamplona F, Moreira E, Moreira K, Hipólide D, Rodrigues D, et al. Cellular prion protein is present in dopaminergic neurons and modulates the dopaminergic system. Eur J Neurosci. 2014;40:2479-86 pubmed publisher

Sanchez Aguilera A, Sánchez Alonso J, Vicente Torres M, Colino A. A novel short-term plasticity of intrinsic excitability in the hippocampal CA1 pyramidal cells. J Physiol. 2014;592:2845-64 pubmed publisher

Shen X, Zhang B, Liang R, Cheng W, Xu W, Luo Y, et al. Central role of Nix in the autophagic response to ochratoxin A. Food Chem Toxicol. 2014;69:202-9 pubmed publisher

Yang Y, Yang W, Yu T, Sung G, Park K, Yoon K, et al. ATF-2/CREB/IRF-3-targeted anti-inflammatory activity of Korean red ginseng water extract. J Ethnopharmacol. 2014;154:218-28 pubmed publisher

Ingeson Carlsson C, Nilsson M. Dual contribution of MAPK and PI3K in epidermal growth factor-induced destabilization of thyroid follicular integrity and invasion of cells into extracellular matrix. Exp Cell Res. 2014;326:210-8 pubmed publisher

Searleman A, Iliuk A, Collier T, Chodosh L, Tao W, Bose R. Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer. Electrophoresis. 2014;35:3463-9 pubmed publisher

Woodson E, Anderson M, Loftus M, Kedes D. Progressive accumulation of activated ERK2 within highly stable ORF45-containing nuclear complexes promotes lytic gammaherpesvirus infection. PLoS Pathog. 2014;10:e1004066 pubmed publisher

Kim S, Toyokawa H, Yamao J, Satoi S, Yanagimoto H, Yamamoto T, et al. Antitumor effect of angiotensin II type 1 receptor blocker losartan for orthotopic rat pancreatic adenocarcinoma. Pancreas. 2014;43:886-90 pubmed publisher

Thushara R, Hemshekhar M, Paul M, Shanmuga Sundaram M, Shankar R, Kemparaju K, et al. Crocin prevents sesamol-induced oxidative stress and apoptosis in human platelets. J Thromb Thrombolysis. 2014;38:321-30 pubmed publisher

Bussi I, Levin G, Golombek D, Agostino P. Involvement of dopamine signaling in the circadian modulation of interval timing. Eur J Neurosci. 2014;40:2299-310 pubmed publisher

Malm M, Bass T, Gudmundsdotter L, Lord M, Frejd F, Ståhl S, et al. Engineering of a bispecific affibody molecule towards HER2 and HER3 by addition of an albumin-binding domain allows for affinity purification and in vivo half-life extension. Biotechnol J. 2014;9:1215-22 pubmed publisher

McAllister F, Pineda D, Jimbo M, Lal S, Burkhart R, Moughan J, et al. dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: a dual-institutional follow-up with the RTOG 9704 trial. Cancer Biol Ther. 2014;15:688-98 pubmed publisher

Wang J, Xia Y, Wang G, Zhou T, Guo Y, Zhang C, et al. In-depth proteomic analysis of whole testis tissue from the adult rhesus macaque. Proteomics. 2014;14:1393-402 pubmed publisher

Iwata T, Fujii T, Morii K, Saito M, Sugiyama J, Nishio H, et al. Cytokine profile in cervical mucosa of Japanese patients with cervical intraepithelial neoplasia. Int J Clin Oncol. 2015;20:126-33 pubmed publisher

Rizza P, Barone I, Zito D, Giordano F, Lanzino M, De Amicis F, et al. Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines. Breast Cancer Res. 2014;16:R21 pubmed publisher

Rhee Y, Chung P, Kim S, Ahn J. CXCR4 and PTEN are involved in the anti-metastatic regulation of anethole in DU145 prostate cancer cells. Biochem Biophys Res Commun. 2014;447:557-62 pubmed publisher

Park G, Choi Y, Kim Y, Lee H, Kim D, Hur D. ROS-mediated JNK/p38-MAPK activation regulates Bax translocation in Sorafenib-induced apoptosis of EBV-transformed B cells. Int J Oncol. 2014;44:977-85 pubmed publisher

Wan C, Hou S, Ni R, Lv L, Ding Z, Huang X, et al. MIF4G domain containing protein regulates cell cycle and hepatic carcinogenesis by antagonizing CDK2-dependent p27 stability. Oncogene. 2015;34:237-45 pubmed publisher

Wright A, Magnaldo T, Sontag R, Anderson L, Sadler N, Piehowski P, et al. Deficient expression of aldehyde dehydrogenase 1A1 is consistent with increased sensitivity of Gorlin syndrome patients to radiation carcinogenesis. Mol Carcinog. 2015;54:473-84 pubmed publisher

Marivin A, Berthelet J, Cartier J, Paul C, Gemble S, Morizot A, et al. cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation. Oncogene. 2014;33:5534-45 pubmed publisher

Hsieh Y, van der Heyde H, Oh E, Guan J, Chang P. Osteopontin mediates tumorigenic transformation of a preneoplastic murine cell line by suppressing anoikis: an Arg-Gly-Asp-dependent-focal adhesion kinase-caspase-8 axis. Mol Carcinog. 2015;54:379-92 pubmed publisher

Sales C, Santos A, Cintra D, Colli C. Magnesium-deficient high-fat diet: effects on adiposity, lipid profile and insulin sensitivity in growing rats. Clin Nutr. 2014;33:879-88 pubmed publisher

Luis Ravelo D, Anton I, Zandueta C, Valencia K, Ormazabal C, Martínez Canarias S, et al. A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer. Oncogene. 2014;33:5090-9 pubmed publisher

Shi M, Liao Y, Shih Y, Tsai L. Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells. Phytomedicine. 2013;20:743-52 pubmed publisher

Wang B, Tanaka K, Morita A, Ninomiya Y, Maruyama K, Fujita K, et al. Sodium orthovanadate (vanadate), a potent mitigator of radiation-induced damage to the hematopoietic system in mice. J Radiat Res. 2013;54:620-9 pubmed publisher

Delwar Z, Siden A, Cruz M, Yakisich J. Menadione : sodium orthovanadate combination eliminates and inhibits migration of detached cancer cells. ISRN Pharmacol. 2012;2012:307102 pubmed publisher

Yang Y, Zhou H, Binmadi N, Proia P, Basile J. Plexin-B1 activates NF-?B and IL-8 to promote a pro-angiogenic response in endothelial cells. PLoS ONE. 2011;6:e25826 pubmed publisher

Qazi A, Halterman M, Mi Z, Zhang T, Schor N. Chopper is prodeath regardless of the effect of p75ICD on sensitivity to oxidative stress. Oxid Med Cell Longev. 2011;2011:391659 pubmed publisher

Giorgio C, Hassan Mohamed I, Flammini L, Barocelli E, Incerti M, Lodola A, et al. Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation. PLoS ONE. 2011;6:e18128 pubmed publisher

Qian S, Li H, Chen Y, Zhang W, Yang S, Wu Y. Synthesis and biological evaluation of oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B. J Nat Prod. 2010;73:1743-50 pubmed publisher

Kumar A, Sharma S, Tripathi V, Maurya R, Srivastava S, Bhatia G, et al. Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents. Bioorg Med Chem. 2010;18:4138-48 pubmed publisher

Bulbul M, Tan R, Gemici B, Ozdem S, Ustunel I, Acar N, et al. Endogenous orexin-A modulates gastric motility by peripheral mechanisms in rats. Peptides. 2010;31:1099-108 pubmed publisher

Hayashida Y, Rodríguez C, Ogata G, Partida G, Oi H, Stradleigh T, et al. Inhibition of adult rat retinal ganglion cells by D1-type dopamine receptor activation. J Neurosci. 2009;29:15001-16 pubmed publisher

Kuo C, Chu C, Lin J, Lo L. Selective activation of SHP2 activity by cisplatin revealed by a novel chemical probe-based assay. Biochem Biophys Res Commun. 2010;391:230-4 pubmed publisher

Koo H, Kang S, Lee J, Kim N, Chung H, Pae H. Triptolide Inhibits the Proliferation of Immortalized HT22 Hippocampal Cells Via Persistent Activation of Extracellular Signal-Regulated Kinase-1/2 by Down-Regulating Mitogen-Activated Protein Kinase Phosphatase-1 Expression. J Korean Neurosurg Soc. 2009;46:389-96 pubmed publisher

Kumar A, Maurya R, Sharma S, Ahmad P, Singh A, Bhatia G, et al. Pyranocoumarins: a new class of anti-hyperglycemic and anti-dyslipidemic agents. Bioorg Med Chem Lett. 2009;19:6447-51 pubmed publisher

Firaguay G, Nunes J. Analysis of signaling events by dynamic phosphoflow cytometry. Sci Signal. 2009;2:pl3 pubmed publisher

Bernaciak T, Zareno J, Parsons J, Silva C. A novel role for signal transducer and activator of transcription 5b (STAT5b) in beta1-integrin-mediated human breast cancer cell migration. Breast Cancer Res. 2009;11:R52 pubmed publisher

Schoeberl B, Pace E, Fitzgerald J, Harms B, Xu L, Nie L, et al. Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis. Sci Signal. 2009;2:ra31 pubmed publisher

Devine P, Hoyer P, Keating A. Current methods in investigating the development of the female reproductive system. Methods Mol Biol. 2009;550:137-57 pubmed publisher

Singh F, Parihar A, Chaurasia S, Singh A, Singh S, Tamrakar A, et al. 5,6-Diarylanthranilo-1,3-dinitriles as a new class of antihyperglycemic agents. Bioorg Med Chem Lett. 2009;19:2158-61 pubmed publisher

Moyer A, Ramadan R, Novosad B, Astley R, Callegan M. Bacillus cereus-induced permeability of the blood-ocular barrier during experimental endophthalmitis. Invest Ophthalmol Vis Sci. 2009;50:3783-93 pubmed publisher

Debnath J. Detachment-induced autophagy in three-dimensional epithelial cell cultures. Methods Enzymol. 2009;452:423-39 pubmed publisher

Prosser S, Straatman K, Fry A. Molecular dissection of the centrosome overduplication pathway in S-phase-arrested cells. Mol Cell Biol. 2009;29:1760-73 pubmed publisher

Wang X, Rao R, Kosakowska Cholody T, Masood M, Southon E, Zhang H, et al. Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice. J Cell Biol. 2009;184:143-58 pubmed publisher

Leung E, Fraser M, Fiscus R, Tsang B. Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: involvement in p53 regulation and cisplatin resistance. Br J Cancer. 2008;98:1803-9 pubmed publisher

Casselli T, Lynch T, Southward C, Jones B, DeVinney R. Vibrio parahaemolyticus inhibition of Rho family GTPase activation requires a functional chromosome I type III secretion system. Infect Immun. 2008;76:2202-11 pubmed publisher

Flanagin S, Nelson J, Castner D, Denisenko O, Bomsztyk K. Microplate-based chromatin immunoprecipitation method, Matrix ChIP: a platform to study signaling of complex genomic events. Nucleic Acids Res. 2008;36:e17 pubmed publisher

Dixit M, Tripathi B, Srivastava A, Goel A. Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors. Bioorg Med Chem Lett. 2005;15:3394-7 pubmed

Sharon A, Pratap R, Tripathi B, Srivastava A, Maulik P, Ram V. Biaryls and heterobiaryls as alpha-glucosidase and protein tyrosine phosphatase inhibitors. Bioorg Med Chem Lett. 2005;15:1341-4 pubmed

Walchli S, Curchod M, Gobert R, Arkinstall S, Hooft van Huijsduijnen R. Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants. J Biol Chem. 2000;275:9792-6 pubmed

Swarup G, Speeg K, Cohen S, Garbers D. Phosphotyrosyl-protein phosphatase of TCRC-2 cells. J Biol Chem. 1982;257:7298-301 pubmed

Cox R, Gilbert P, Griffin M. Alkaline inorganic pyrophosphatase activity of mammalian-cell alkaline phosphatase. Biochem J. 1967;105:155-61 pubmed

Stankiewicz P, Gresser M. Inhibition of phosphatase and sulfatase by transition-state analogues. Biochemistry. 1988;27:206-12 pubmed

Gordon J. Use of vanadate as protein-phosphotyrosine phosphatase inhibitor. Methods Enzymol. 1991;201:477-82 pubmed

Munoz P, Guma A, Camps M, Furriols M, Testar X, Palacin M, et al. Vanadate stimulates system A amino acid transport activity in skeletal muscle. Evidence for the involvement of intracellular pH as a mediator of vanadate action. J Biol Chem. 1992;267:10381-8 pubmed