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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
N-Succinyl-Ala-Ala-Ala-p-nitroanilide
catalog :
S4760
citations: 50
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Wang L, Lee W, Oh J, Cui Y, Ryu B, Jeon Y. Protective Effect of Sulfated Polysaccharides from Celluclast-Assisted Extract of Hizikia fusiforme Against Ultraviolet B-Induced Skin Damage by Regulating NF-κB, AP-1, and MAPKs Signaling Pathways In Vitro in Human Dermal Fibroblasts. Mar Drugs. 2018;16: pubmed publisher
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You C, Arvizo R, Rotello V. Regulation of alpha-chymotrypsin activity on the surface of substrate-functionalized gold nanoparticles. Chem Commun (Camb). 2006;:2905-7 pubmed
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Kocabiyik S, Ozdemir I. Purification and characterization of an intracellular chymotrypsin-like serine protease from Thermoplasma volcanium. Biosci Biotechnol Biochem. 2006;70:126-34 pubmed
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Steuerwald A, Villeneuve J, Sun L, Stenken J. In vitro characterization of an in situ microdialysis sampling assay for elastase activity detection. J Pharm Biomed Anal. 2006;40:1041-7 pubmed
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Volpi N. Inhibition of human leukocyte elastase activity by chondroitin sulfates. Chem Biol Interact. 1997;105:157-67 pubmed
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Roy P, Colas B, Durand P. Purification, kinetical and molecular characterizations of a serine collagenolytic protease from greenshore crag (Carcinus maenas) digestive gland. Comp Biochem Physiol B Biochem Mol Biol. 1996;115:87-95 pubmed
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Uitto V, Nieminen A, Coil J, Hurttia H, Larjava H. Oral fluid elastase as an indicator of periodontal health. J Clin Periodontol. 1996;23:30-7 pubmed
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Wolz R. A kinetic comparison of the homologous proteases astacin and meprin A. Arch Biochem Biophys. 1994;310:144-51 pubmed
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Harvey S, Vrabel A, Smith S, Wieben E. Androgen regulation of an elastase-like protease activity in the seminal vesicle. Biol Reprod. 1995;52:1059-65 pubmed
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Bieth J, Spiess B, Wermuth C. The synthesis and analytical use of a highly sensitive and convenient substrate of elastase. Biochem Med. 1974;11:350-7 pubmed
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Ogawa M, Nishibe S, Mori T, Neumann S. Effect of human urinary trypsin inhibitor on granulocyte elastase activity. Res Commun Chem Pathol Pharmacol. 1987;55:271-4 pubmed
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Gardi C, Lungarella G. Isolation and partial characterization of rat elastolytic enzymes from various cells and tissues. Arch Biochem Biophys. 1986;250:63-9 pubmed
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Fera T, Abboud R, Richter A, Johal S. Acute effect of smoking on elastaselike esterase activity and immunologic neutrophil elastase levels in bronchoalveolar lavage fluid. Am Rev Respir Dis. 1986;133:568-73 pubmed
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Watanabe Y, Kumagai Y, Shimamori Y, Fujimoto Y. Purification and characterization of a membrane-bound neutral endopeptidase from human placenta. Biochem Med Metab Biol. 1987;37:22-30 pubmed
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Redini F, Tixier J, Petitou M, Choay J, Robert L, Hornebeck W. Inhibition of leucocyte elastase by heparin and its derivatives. Biochem J. 1988;252:515-9 pubmed
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Franck C, Byrjalsen I. A simple and sensitive chromogen assay for the measurement of elastase-type enzyme activity in human plasma. Biol Chem Hoppe Seyler. 1988;369:677-82 pubmed
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Schwartz E, Cruickshank F, Lebwohl M. Elastase-like protease and elastolytic activities expressed in cultured dermal fibroblasts derived from lesional skin of patients with pseudoxanthoma elasticum, actinic elastosis, and cutis laxa. Clin Chim Acta. 1988;176:219-24 pubmed
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Redini F, Lafuma C, Pujol J, Robert L, Hornebeck W. Effect of cytokines and growth factors on the expression of elastase activity by human synoviocytes, dermal fibroblasts and rabbit articular chondrocytes. Biochem Biophys Res Commun. 1988;155:786-93 pubmed
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Ishida M, Ogawa M, Mori T, Mega T. Determination and characterization of succinyl tri-alanine p-nitroanilide hydrolyzing metalloendopeptidase in serum. Enzyme. 1987;37:202-7 pubmed
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Ooyama T, Fukuda K, Masuda S, Nakamura H. Administration of elastase blocks the formation of fragmented elastic fibers in aorta of rabbit. Artery. 1989;16:293-311 pubmed
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Ito Y, Fukaya Y, Ohno Y, Matsumoto T, Yoshitomi S, Kurita H. Serum succinyltrialanine p-nitroanilide-hydrolytic activity in workers occupationally exposed to lead. Toxicol Lett. 1989;48:83-91 pubmed
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Kramps J, Morrison H, Burnett D, Dijkman J, Stockley R. Determination of elastase inhibitory activity of alpha 1-proteinase inhibitor and bronchial antileukoprotease: different results using insoluble elastin or synthetic low molecular weight substrates. Scand J Clin Lab Invest. 1987;47:405-10 pubmed
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Rouis M, Nigon F, Lafuma C, Hornebeck W, Chapman M. Expression of elastase activity by human monocyte-macrophages is modulated by cellular cholesterol content, inflammatory mediators, and phorbol myristate acetate. Arteriosclerosis. 1990;10:246-55 pubmed
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Sibille Y, Martinot J, Polomski L, Wallaert B, Demusis M, Rankin J, et al. Phagocyte enzymes in bronchoalveolar lavage from patients with pulmonary sarcoidosis and collagen vascular disorders. Eur Respir J. 1990;3:249-56 pubmed
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Orstan A, Gafni A. Inhibition of proteinase K by phosphorylated sugars. Biochem Int. 1991;25:657-62 pubmed
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Hornebeck W, Homsy R, Ayrault Jarrier M, Stanislavski L, Robert L. Characterization of metalloelastase-like activity from the plasma of a patient with Tangier disease. Biol Chem Hoppe Seyler. 1991;372:1057-64 pubmed
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Gminski J, Drozdz M. Succinyl trialanine p-nitroanilide hydrolytic activities in plasma and the aorta of rabbits experimentally immunized with soluble elastin. Exp Pathol. 1991;43:37-40 pubmed
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product information
Catalog Number :
S4760
Product Name :
N-Succinyl-Ala-Ala-Ala-p-nitroanilide
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
elastase substrate
company information

MilliporeSigma
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