This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Spectrin from human erythrocytes
catalog :
S3644
citations: 49
Reference
Neumann B, Coakley S, Giordano Santini R, Linton C, Lee E, Nakagawa A, et al. EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway. Nature. 2015;517:219-22 pubmed publisher
Mozar A, Grau M, Lamarre Y, Weyel L, Suhr F, Collins B, et al. Red blood cell nitric oxide synthase activation is increased in patients with sickle cell hemoglobin C disease. Am J Hematol. 2015;90:E30-2 pubmed publisher
Ho T, Zollinger D, Chang K, Xu M, Cooper E, Stankewich M, et al. A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier. Nat Neurosci. 2014;17:1664-72 pubmed publisher
Armbrust K, Wang X, Hathorn T, Cramer S, Chen G, Zu T, et al. Mutant ?-III spectrin causes mGluR1? mislocalization and functional deficits in a mouse model of spinocerebellar ataxia type 5. J Neurosci. 2014;34:9891-904 pubmed publisher
Morais de Sá E, Mukherjee A, Lowe N, St Johnston D. Slmb antagonises the aPKC/Par-6 complex to control oocyte and epithelial polarity. Development. 2014;141:2984-92 pubmed publisher
Keilhoff G, Lucas B, Pinkernelle J, Steiner M, Fansa H. Effects of cerebrolysin on motor-neuron-like NSC-34 cells. Exp Cell Res. 2014;327:234-55 pubmed publisher
Amor V, Feinberg K, Eshed Eisenbach Y, Vainshtein A, Frechter S, Grumet M, et al. Long-term maintenance of Na+ channels at nodes of Ranvier depends on glial contact mediated by gliomedin and NrCAM. J Neurosci. 2014;34:5089-98 pubmed publisher
Sheldon R, Lee C, Jiang X, Knox R, Ferriero D. Hypoxic preconditioning protection is eliminated in HIF-1α knockout mice subjected to neonatal hypoxia-ischemia. Pediatr Res. 2014;76:46-53 pubmed publisher
Trinh Trang Tan M, Bigot S, Picot J, Lecomte M, Kordeli E. AlphaII-spectrin participates in the surface expression of cell adhesion molecule L1 and neurite outgrowth. Exp Cell Res. 2014;322:365-80 pubmed publisher
Kwa L, Wensley B, Alexander C, Browning S, Lichman B, Clarke J. The folding of a family of three-helix bundle proteins: spectrin R15 has a robust folding nucleus, unlike its homologous neighbours. J Mol Biol. 2014;426:1600-10 pubmed publisher
Mohandas N. An open-and-shut case?. Blood. 2013;122:2928-9 pubmed publisher
Andres A, Regev L, Phi L, Seese R, Chen Y, Gall C, et al. NMDA receptor activation and calpain contribute to disruption of dendritic spines by the stress neuropeptide CRH. J Neurosci. 2013;33:16945-60 pubmed publisher
King M, Phillips G, Bignone P, Hayes N, Pinder J, Baines A. A conserved sequence in calmodulin regulated spectrin-associated protein 1 links its interaction with spectrin and calmodulin to neurite outgrowth. J Neurochem. 2014;128:391-402 pubmed publisher
Baines A. Link up and fold up--templating the formation of spectrin tetramers. J Mol Biol. 2014;426:7-10 pubmed publisher
Kline C, Wright P, Koval O, Zmuda E, Johnson B, Anderson M, et al. ?IV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells. Proc Natl Acad Sci U S A. 2013;110:17576-81 pubmed publisher
Hill S, Kwa L, Shammas S, Lee J, Clarke J. Mechanism of assembly of the non-covalent spectrin tetramerization domain from intrinsically disordered partners. J Mol Biol. 2014;426:21-35 pubmed publisher
Xuan Z, Barthet G, Shioi J, Xu J, Georgakopoulos A, Bruban J, et al. Presenilin-1/γ-secretase controls glutamate release, tyrosine phosphorylation, and surface expression of N-methyl-D-aspartate receptor (NMDAR) subunit GluN2B. J Biol Chem. 2013;288:30495-501 pubmed publisher
Harper S, Sriswasdi S, Tang H, Gaetani M, Gallagher P, Speicher D. The common hereditary elliptocytosis-associated ?-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation. Blood. 2013;122:3045-53 pubmed publisher
Berezniakova A, Zhemela O. [Deformability of the erythrocytes membrane in rats of different age in hypoxia]. Fiziol Zh. 2013;59:72-7 pubmed
Ruzafa D, Conejero Lara F, Morel B. Modulation of the stability of amyloidogenic precursors by anion binding strongly influences the rate of amyloid nucleation. Phys Chem Chem Phys. 2013;15:15508-17 pubmed publisher
Dong Z, Qi J, Peng H, Liu J, Zhang J. Spectrin domain of eukaryotic initiation factor 3a is the docking site for formation of the a:b:i:g subcomplex. J Biol Chem. 2013;288:27951-9 pubmed publisher
Tögel M, Meyer H, Lehmacher C, Heinisch J, Pass G, Paululat A. The bHLH transcription factor hand is required for proper wing heart formation in Drosophila. Dev Biol. 2013;381:446-59 pubmed publisher
Wilson A, Schoenauer R, Ehler E, Agarkova I, Bennett P. Cardiomyocyte growth and sarcomerogenesis at the intercalated disc. Cell Mol Life Sci. 2014;71:165-81 pubmed publisher
Vesely M, Schreiber R. Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy. Ann N Y Acad Sci. 2013;1284:1-5 pubmed publisher
Ayllón N, Villar M, Busby A, Kocan K, Blouin E, Bonzon Kulichenko E, et al. Anaplasma phagocytophilum inhibits apoptosis and promotes cytoskeleton rearrangement for infection of tick cells. Infect Immun. 2013;81:2415-25 pubmed publisher
Toporkiewicz M, Grzybek M, Meissner J, Michalczyk I, Dubielecka P, Korycka J, et al. Release of an ~55kDa fragment containing the actin-binding domain of β-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1. Arch Biochem Biophys. 2013;535:205-13 pubmed publisher
Zhang P, Herbig U, Coffman F, Lambert M. Non-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage. Nucleic Acids Res. 2013;41:5321-40 pubmed publisher
Ishihara M, Araya N, Sato T, Tatsuguchi A, Saichi N, Utsunomiya A, et al. Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia. Blood. 2013;121:4340-7 pubmed publisher
Rasband M. Cytoskeleton: axons earn their stripes. Curr Biol. 2013;23:R197-8 pubmed publisher
Dai L, Lidie K, Chen Q, Adelsberger J, Zheng X, Huang D, et al. IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation. J Exp Med. 2013;210:517-34 pubmed publisher
Siegel C, McCullough L. NAD+ and nicotinamide: sex differences in cerebral ischemia. Neuroscience. 2013;237:223-31 pubmed publisher
Budhram R, Pandya K, Lau Cam C. Protection by taurine and thiotaurine against biochemical and cellular alterations induced by diabetes in a rat model. Adv Exp Med Biol. 2013;775:321-43 pubmed publisher
Wolny M, Wróblewska A, Machnicka B, Sikorski A. [Spectrin--variety of functions hidden in the structure]. Postepy Biochem. 2012;58:245-54 pubmed
Picas L, Rico F, Deforet M, Scheuring S. Structural and mechanical heterogeneity of the erythrocyte membrane reveals hallmarks of membrane stability. ACS Nano. 2013;7:1054-63 pubmed publisher
Schoch K, von Reyn C, Bian J, Telling G, Meaney D, Saatman K. Brain injury-induced proteolysis is reduced in a novel calpastatin-overexpressing transgenic mouse. J Neurochem. 2013;125:909-20 pubmed publisher
Duregotti E, Tedesco E, Montecucco C, Rigoni M. Calpains participate in nerve terminal degeneration induced by spider and snake presynaptic neurotoxins. Toxicon. 2013;64:20-8 pubmed publisher
van Zwieten R, François J, van Leeuwen K, van Wesel A, van Bruggen R, van Solinge W, et al. Hereditary spherocytosis due to band 3 deficiency: 15 novel mutations in SLC4A1. Am J Hematol. 2013;88:159-60 pubmed publisher
Randles L, Dawes G, Wensley B, Steward A, Nickson A, Clarke J. Understanding pathogenic single-nucleotide polymorphisms in multidomain proteins--studies of isolated domains are not enough. FEBS J. 2013;280:1018-27 pubmed publisher
Xu K, Zhong G, Zhuang X. Actin, spectrin, and associated proteins form a periodic cytoskeletal structure in axons. Science. 2013;339:452-6 pubmed publisher
Lise S, Clarkson Y, Perkins E, Kwasniewska A, Sadighi Akha E, Schnekenberg R, et al. Recessive mutations in SPTBN2 implicate β-III spectrin in both cognitive and motor development. PLoS Genet. 2012;8:e1003074 pubmed publisher
Salcedo Sicilia L, Granell S, Jovic M, Sicart A, Mato E, Johannes L, et al. ?III spectrin regulates the structural integrity and the secretory protein transport of the Golgi complex. J Biol Chem. 2013;288:2157-66 pubmed publisher
Ciana A, Achilli C, Hannoush R, Risso A, Balduini C, Minetti G. Freely turning over palmitate in erythrocyte membrane proteins is not responsible for the anchoring of lipid rafts to the spectrin skeleton: a study with bio-orthogonal chemical probes. Biochim Biophys Acta. 2013;1828:924-31 pubmed publisher
Bains M, Cebak J, Gilmer L, Barnes C, Thompson S, Geddes J, et al. Pharmacological analysis of the cortical neuronal cytoskeletal protective efficacy of the calpain inhibitor SNJ-1945 in a mouse traumatic brain injury model. J Neurochem. 2013;125:125-32 pubmed publisher
Shammas S, Rogers J, Hill S, Clarke J. Slow, reversible, coupled folding and binding of the spectrin tetramerization domain. Biophys J. 2012;103:2203-14 pubmed publisher
Lai Y, Zhao J, Yue Y, Duan D. ?2 and ?3 helices of dystrophin R16 and R17 frame a microdomain in the ?1 helix of dystrophin R17 for neuronal NOS binding. Proc Natl Acad Sci U S A. 2013;110:525-30 pubmed publisher
Bellstedt P, Herbst C, Häfner S, Leppert J, Görlach M, Ramachandran R. Solid state NMR of proteins at high MAS frequencies: symmetry-based mixing and simultaneous acquisition of chemical shift correlation spectra. J Biomol NMR. 2012;54:325-35 pubmed publisher
Borgia A, Wensley B, Soranno A, Nettels D, Borgia M, Hoffmann A, et al. Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy. Nat Commun. 2012;3:1195 pubmed publisher
He M, Jenkins P, Bennett V. Cysteine 70 of ankyrin-G is S-palmitoylated and is required for function of ankyrin-G in membrane domain assembly. J Biol Chem. 2012;287:43995-4005 pubmed publisher
Korsgren C, Lux S. The carboxyterminal EF domain of erythroid alpha-spectrin is necessary for optimal spectrin-actin binding. Blood. 2010;116:2600-7 pubmed publisher
product information
Catalog Number :
S3644
Product Name :
Spectrin from human erythrocytes
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
buffered aqueous glycerol solution
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA