product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-α-Synuclein antibody produced in rabbit
catalog :
S3062
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4a
  • western blot; mouse; 1:1000; loading ...; fig 6a
  • immunocytochemistry; human; 1:1000; loading ...; fig 1c
  • western blot; human; 1:1000; loading ...; fig 2
Cholanians A, Phan A, Ditzel E, Camenisch T, Lau S, Monks T. From the Cover: Arsenic Induces Accumulation of α-Synuclein: Implications for Synucleinopathies and Neurodegeneration. Toxicol Sci. 2016;153:271-81 pubmed publisher
Olah J, Szunyogh S, Szénási T, Szaniszlo T, Szabó A, Lehotzky A, et al. Interactions between two regulatory proteins of microtubule dynamics, HDAC6, TPPP/p25, and the hub protein, DYNLL/LC8. Biochim Biophys Acta Mol Cell Res. 2019;1866:118556 pubmed publisher
Luo Z, Ahlers Dannen K, Spicer M, Yang J, Alberico S, Stevens H, et al. Age-dependent nigral dopaminergic neurodegeneration and α-synuclein accumulation in RGS6-deficient mice. JCI Insight. 2019;5: pubmed publisher
Naletova I, Satriano C, Pietropaolo A, Gianì F, Pandini G, Triaca V, et al. The Copper(II)-Assisted Connection between NGF and BDNF by Means of Nerve Growth Factor-Mimicking Short Peptides. Cells. 2019;8: pubmed publisher
Li H, Ham A, Ma T, Kuo S, Kanter E, Kim D, et al. Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations. Autophagy. 2019;15:113-130 pubmed publisher
Latina V, Caioli S, Zona C, Ciotti M, Borreca A, Calissano P, et al. NGF-Dependent Changes in Ubiquitin Homeostasis Trigger Early Cholinergic Degeneration in Cellular and Animal AD-Model. Front Cell Neurosci. 2018;12:487 pubmed publisher
de Camargo L, de Carvalho M, Shinjo S, de Oliveira A, Zanoteli E. Clinical, Histological, and Immunohistochemical Findings in Inclusion Body Myositis. Biomed Res Int. 2018;2018:5069042 pubmed publisher
Florenzano F, Veronica C, Ciasca G, Ciotti M, Pittaluga A, Olivero G, et al. Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies. Oncotarget. 2017;8:64745-64778 pubmed publisher
Morales I, Sánchez A, Rodriguez Sabate C, Rodriguez M. Striatal astrocytes engulf dopaminergic debris in Parkinson's disease: A study in an animal model. PLoS ONE. 2017;12:e0185989 pubmed publisher
Aufschnaiter A, Habernig L, Kohler V, Diessl J, Carmona Gutierrez D, Eisenberg T, et al. The Coordinated Action of Calcineurin and Cathepsin D Protects Against α-Synuclein Toxicity. Front Mol Neurosci. 2017;10:207 pubmed publisher
Latina V, Caioli S, Zona C, Ciotti M, Amadoro G, Calissano P. Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons. Front Cell Neurosci. 2017;11:68 pubmed publisher
Kim Y, Miller A, Lins L, Han S, Keiser M, Boudreau R, et al. RNA Interference of Human α-Synuclein in Mouse. Front Neurol. 2017;8:13 pubmed publisher
Dráberová E, Sulimenko V, Vinopal S, Sulimenko T, Sladkova V, D Agostino L, et al. Differential expression of human ?-tubulin isotypes during neuronal development and oxidative stress points to a ?-tubulin-2 prosurvival function. FASEB J. 2017;31:1828-1846 pubmed publisher
Kaur G, Pawlik M, Gandy S, Ehrlich M, Smiley J, Levy E. Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein. Mol Psychiatry. 2017;22:981-989 pubmed publisher
product information
Product No. :
S3062
Product Name :
Anti-α-Synuclein antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200 using formic acid treated sections of Alzheimer′s Disease brain; western blot: 1:1,000 using extract of rat brain homogenate; microarray
Species Reactivity :
rat, human
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA