Anti-SMN antibody, Mouse monoclonal | MilliporeSigma S2944 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MilliporeSigma

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science

product type :

antibody

product name :

Anti-SMN antibody, Mouse monoclonal

catalog :

S2944

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B1

reactivity :

human, mouse

application :

western blot

citations: 10

Reference
Conlon E, Fagegaltier D, Agius P, Davis Porada J, Gregory J, Hubbard I, et al. Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism. elife. 2018;7: pubmed publisher
Garcia Lopez A, Tessaro F, Jonker H, Wacker A, Richter C, Comte A, et al. Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes. Nat Commun. 2018;9:2032 pubmed publisher
Li Y, Collins M, An J, Geiser R, Tegeler T, Tsantilas K, et al. Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network. Brain Res. 2016;1647:79-93 pubmed publisher
Hemdan T, Linden M, Lind S, Namuduri A, Sjöstedt E, de Ståhl T, et al. The prognostic value and therapeutic target role of stathmin-1 in urinary bladder cancer. Br J Cancer. 2014;111:1180-7 pubmed publisher
Crawford T, Paushkin S, Kobayashi D, Forrest S, JOYCE C, Finkel R, et al. Evaluation of SMN protein, transcript, and copy number in the biomarkers for spinal muscular atrophy (BforSMA) clinical study. PLoS ONE. 2012;7:e33572 pubmed publisher
Kobayashi D, Olson R, Sly L, Swanson C, Chung B, Naryshkin N, et al. Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses. PLoS ONE. 2011;6:e24269 pubmed publisher
Paushkin S, Gubitz A, Massenet S, Dreyfuss G. The SMN complex, an assemblyosome of ribonucleoproteins. Curr Opin Cell Biol. 2002;14:305-12 pubmed
Baccon J, Pellizzoni L, Rappsilber J, Mann M, Dreyfuss G. Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. J Biol Chem. 2002;277:31957-62 pubmed
Charroux B, Pellizzoni L, Perkinson R, Shevchenko A, Mann M, Dreyfuss G. Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. J Cell Biol. 1999;147:1181-94 pubmed
Liu Q, Dreyfuss G. A novel nuclear structure containing the survival of motor neurons protein. EMBO J. 1996;15:3555-65 pubmed

product information

Product No. :

S2944

Product Name :

Anti-SMN antibody, Mouse monoclonal

Host :

mouse

Conjugate :

unconjugated

Antibody Type :

monoclonal

Clone Number (if monoclonal) :

2B1

Applications/Description :

Suitable for microarray; western blot: 2-4 μg/mL using A431 cell extract

Species Reactivity :

Xenopus, mouse, human

Isotype :

IgG1

Concentration :

~2 mg/mL

Storage :

Store at -20°C