This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
(±)-Sotalol hydrochloride
catalog :
S0278
citations: 39
Reference
Nash C, Wei W, Irannejad R, Smrcka A. Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy. elife. 2019;8: pubmed publisher
Hayes H, Nicolini A, Arrowood C, Chvatal S, Wolfson D, Cho H, et al. Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology. Sci Rep. 2019;9:11893 pubmed publisher
Stancescu M, Molnar P, McAleer C, McLamb W, Long C, Oleaga C, et al. A phenotypic in vitro model for the main determinants of human whole heart function. Biomaterials. 2015;60:20-30 pubmed publisher
Allen LaPointe N, Dai D, Thomas L, Piccini J, Peterson E, Al Khatib S. Antiarrhythmic drug use in patients <65 years with atrial fibrillation and without structural heart disease. Am J Cardiol. 2015;115:316-22 pubmed publisher
Van Asbroeck P, Huybrechts W, De Soir R. Case report, aetiology, and treatment of an acquired long-QT syndrome. Acta Clin Belg. 2014;69:132-4 pubmed publisher
Leslie S. Sotalol-associated cardiogenic shock in a patient with asymptomatic transient rate-related cardiomyopathy. Med J Aust. 2013;199:658-9 pubmed
Juvet T, Gourineni V, Ravi S, Zarich S. Life-threatening hyperkalemia: a potentially lethal drug combination. Conn Med. 2013;77:491-3 pubmed
Piccini J, Zhao Y, Steinberg B, He X, Mathew J, Fullerton D, et al. Comparative effectiveness of pharmacotherapies for prevention of atrial fibrillation following coronary artery bypass surgery. Am J Cardiol. 2013;112:954-60 pubmed publisher
DeLillo D, Jesty S, Souza M. Episodic syncope caused by ventricular flutter in a tiger (Panthera tigris). J Zoo Wildl Med. 2013;44:500-4 pubmed
Thelle D, Selmer R, Gjesdal K, Sakshaug S, Jugessur A, Graff Iversen S, et al. Resting heart rate and physical activity as risk factors for lone atrial fibrillation: a prospective study of 309,540 men and women. Heart. 2013;99:1755-60 pubmed publisher
Höjer J. [QTc-prolongation in acute drug-poisoning. Guidelines for management from the Swedish Poisons Information Centre]. Lakartidningen. 2013;110:953-5 pubmed
Deftereos S, Giannopoulos G, Kossyvakis C, Efremidis M, Panagopoulou V, Raisakis K, et al. Effectiveness of moxonidine to reduce atrial fibrillation burden in hypertensive patients. Am J Cardiol. 2013;112:684-7 pubmed publisher
Arsenault K, Yusuf A, Crystal E, Healey J, Morillo C, Nair G, et al. Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery. Cochrane Database Syst Rev. 2013;:CD003611 pubmed publisher
Arnold J, Hansen M, Gorman G, Inoue T, Rao V, Spellen S, et al. The effect of Rho-associated kinase inhibition on the ocular penetration of timolol maleate. Invest Ophthalmol Vis Sci. 2013;54:1118-26 pubmed publisher
Frommeyer G, Rajamani S, Grundmann F, Stypmann J, Osada N, Breithardt G, et al. New insights into the beneficial electrophysiologic profile of ranolazine in heart failure: prevention of ventricular fibrillation with increased postrepolarization refractoriness and without drug-induced proarrhythmia. J Card Fail. 2012;18:939-49 pubmed publisher
Obrenovic Kircanski B, Orbović B, Vranes M, Parapid B, Kovacevic Kostic N, Velinovic M, et al. [Atrial fibrillation after coronary artery bypass surgery: possibilities of prevention]. Srp Arh Celok Lek. 2012;140:521-7 pubmed
Braam S, Tertoolen L, Casini S, Matsa E, Lu H, Teisman A, et al. Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes. Stem Cell Res. 2013;10:48-56 pubmed publisher
Baumert M, Starc V, Porta A. Conventional QT variability measurement vs. template matching techniques: comparison of performance using simulated and real ECG. PLoS ONE. 2012;7:e41920 pubmed publisher
Isaza C, Trombert V. [Practical ECG problems. Torsade de pointes in an elderly patient]. Rev Med Suisse. 2012;8:1025 pubmed
Antony Muthu Prabhu A, Subramanian V, Rajendiran N. Excimer formation in inclusion complexes of β-cyclodextrin with salbutamol, sotalol and atenolol: spectral and molecular modeling studies. Spectrochim Acta A Mol Biomol Spectrosc. 2012;96:95-107 pubmed publisher
Drimba L, Hegedus C, Yin D, Sari R, Nemeth J, Szilvassy Z, et al. Beneficial cardiac effects of cicletanine in conscious rabbits with metabolic syndrome. J Cardiovasc Pharmacol. 2012;60:208-18 pubmed publisher
Nguemo F, Saric T, Pfannkuche K, Watzele M, Reppel M, Hescheler J. In vitro model for assessing arrhythmogenic properties of drugs based on high-resolution impedance measurements. Cell Physiol Biochem. 2012;29:819-32 pubmed publisher
Hariman R, Khin M, Zoble R. Wide QRS Tachycardia in a young patient. Arch Intern Med. 2012;172:537; discussion 538-9 pubmed publisher
Shah A, Moon Grady A, Bhogal N, Collins K, Tacy T, Brook M, et al. Effectiveness of sotalol as first-line therapy for fetal supraventricular tachyarrhythmias. Am J Cardiol. 2012;109:1614-8 pubmed publisher
Liu X, Limberis J, Su Z, Houseman K, Diaz G, Gintant G, et al. Characterization of A-935142, a hERG enhancer, in the presence and absence of standard hERG blockers. Life Sci. 2012;90:607-11 pubmed publisher
Liu W, Okochi H, Benet L, Zhai S. Sotalol permeability in cultured-cell, rat intestine, and PAMPA system. Pharm Res. 2012;29:1768-74 pubmed publisher
Burashnikov A, Pourrier M, Gibson J, Lynch J, Antzelevitch C. Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol. Circ Arrhythm Electrophysiol. 2012;5:400-8 pubmed publisher
Yamakawa Y, Furutani K, Inanobe A, Ohno Y, Kurachi Y. Pharmacophore modeling for hERG channel facilitation. Biochem Biophys Res Commun. 2012;418:161-6 pubmed publisher
Goodman I, Lu C. Intraosseous infusion is unreliable for adenosine delivery in the treatment of supraventricular tachycardia. Pediatr Emerg Care. 2012;28:47-8 pubmed publisher
Kumar S, Sutherland F, Morton J, Lee G, Morgan J, Wong J, et al. Long-term omega-3 polyunsaturated fatty acid supplementation reduces the recurrence of persistent atrial fibrillation after electrical cardioversion. Heart Rhythm. 2012;9:483-91 pubmed publisher
Clusin W. Role of sodium/calcium exchange in heart failure-induced arrhythmias: a potential therapeutic target. Heart Rhythm. 2012;9:579-80 pubmed publisher
Kim M, Smith P, Jhaveri M, Lin J, Klingman D. One-year treatment persistence and potential adverse events among patients with atrial fibrillation treated with amiodarone or sotalol: a retrospective claims database analysis. Clin Ther. 2011;33:1668-1681.e1 pubmed publisher
Milberg P, Pott C, Frommeyer G, Fink M, Ruhe M, Matsuda T, et al. Acute inhibition of the Na(+)/Ca(2+) exchanger reduces proarrhythmia in an experimental model of chronic heart failure. Heart Rhythm. 2012;9:570-8 pubmed publisher
Franz M, Singh S. Comparative pharmacophysiology of vernakalant, ranolazine, and d-sotalol in canine pulmonary vein sleeve preparations: new flavors or same old taste?. Heart Rhythm. 2012;9:430-1 pubmed publisher
Sicouri S, Pourrier M, Gibson J, Lynch J, Antzelevitch C. Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations. Heart Rhythm. 2012;9:422-9 pubmed publisher
Schmalhofer W, Swensen A, Thomas B, Felix J, Haedo R, Solly K, et al. A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel. Assay Drug Dev Technol. 2010;8:714-26 pubmed publisher
Doggrell S. The effects of (+/-)-, (+)-, and (-)-atenolol, sotalol, and amosulalol on the rat left atria and portal vein. Chirality. 1993;5:8-14 pubmed
Pasnani J, Ferrier G. Pro- and antiarrhythmic effects of d-sotalol and dl-sotalol in an isolated tissue model of ischemia and reperfusion. J Pharmacol Exp Ther. 1994;271:184-92 pubmed
Groh W, Gibson K, McAnulty J, Maylie J. Beta-adrenergic blocking property of dl-sotalol maintains class III efficacy in guinea pig ventricular muscle after isoproterenol. Circulation. 1995;91:262-4 pubmed
product information
Catalog Number :
S0278
Product Name :
(±)-Sotalol hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (TLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA