This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Ribonuclease A from bovine pancreas
catalog :
R4875
citations: 105
Reference
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Leturcq M, Mortuaire M, Hardiville S, Schulz C, Lefebvre T, Vercoutter Edouart A. O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions. Cell Mol Life Sci. 2018;75:4321-4339 pubmed publisher
Katorcha E, Gonzalez Montalban N, Makarava N, Kovacs G, Baskakov I. Prion replication environment defines the fate of prion strain adaptation. PLoS Pathog. 2018;14:e1007093 pubmed publisher
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Yang W, Lee Y, Jones A, Woolnough J, Zhou D, Dai Q, et al. The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment. Nat Commun. 2014;5:3818 pubmed publisher
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Jönsson U, Blom K, Stålenheim G, Håkansson L, Venge P. The production of the eosinophil proteins ECP and EPX/EDN are regulated in a reciprocal manner. APMIS. 2014;122:283-91 pubmed publisher
Babkina I, Kuznetsov I, Soloviev Y, Russo E, Ten E. Angiogenic factors in blood serum of bone tumor patients. Klin Lab Diagn. 2013;:63-5, 31-3 pubmed
Spadaccini R, Ercole C, Graziano G, Wechselberger R, Boelens R, Picone D. Mechanism of 3D domain swapping in bovine seminal ribonuclease. FEBS J. 2014;281:842-50 pubmed
Hayashi N, Kuyama H, Nakajima C, Kawahara K, Miyagi M, Nishimura O, et al. Imidazole C-2 hydrogen/deuterium exchange reaction at histidine for probing protein structure and function with matrix-assisted laser desorption ionization mass spectrometry. Biochemistry. 2014;53:1818-26 pubmed publisher
Fiorini C, Gotte G, Donnarumma F, Picone D, Donadelli M. Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells. Biochim Biophys Acta. 2014;1843:976-84 pubmed publisher
Juntawong P, Girke T, Bazin J, Bailey Serres J. Translational dynamics revealed by genome-wide profiling of ribosome footprints in Arabidopsis. Proc Natl Acad Sci U S A. 2014;111:E203-12 pubmed publisher
Premzl M. Comparative genomic analysis of eutherian ribonuclease A genes. Mol Genet Genomics. 2014;289:161-7 pubmed publisher
Premkumar L, Kurth F, Neyer S, Schembri M, Martin J. The multidrug resistance IncA/C transferable plasmid encodes a novel domain-swapped dimeric protein-disulfide isomerase. J Biol Chem. 2014;289:2563-76 pubmed publisher
Damodaran S. Electrodynamic pressure modulation of protein stability in cosolvents. Biochemistry. 2013;52:8363-73 pubmed publisher
Sheng J, Yu W, Gao X, Xu Z, Hu G. Angiogenin stimulates ribosomal RNA transcription by epigenetic activation of the ribosomal DNA promoter. J Cell Physiol. 2014;229:521-9 pubmed publisher
Gotte G, Laurents D, Merlino A, Picone D, Spadaccini R. Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: new scaffolds for potential antitumor drugs. FEBS Lett. 2013;587:3601-8 pubmed publisher
Pica A, Merlino A, Buell A, Knowles T, Pizzo E, D Alessio G, et al. Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase. Acta Crystallogr D Biol Crystallogr. 2013;69:2116-23 pubmed publisher
Vergara A, Russo Krauss I, Montesarchio D, Paduano L, Merlino A. Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu. Inorg Chem. 2013;52:10714-6 pubmed publisher
Köberle V, Pleli T, Schmithals C, Augusto Alonso E, Haupenthal J, Bonig H, et al. Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers. PLoS ONE. 2013;8:e75184 pubmed publisher
Pulido D, Moussaoui M, Nogués M, Torrent M, Boix E. Towards the rational design of antimicrobial proteins: single point mutations can switch on bactericidal and agglutinating activities on the RNase A superfamily lineage. FEBS J. 2013;280:5841-52 pubmed publisher
Wong M, Khirich G, Loria J. What's in your buffer? Solute altered millisecond motions detected by solution NMR. Biochemistry. 2013;52:6548-58 pubmed publisher
Kim K, Park S, Wee S, Kim J. Overexpression of angiogenin in pterygium body fibroblasts and its association with proliferative potency. Invest Ophthalmol Vis Sci. 2013;54:6355-62 pubmed publisher
Bottero V, Sadagopan S, Johnson K, Dutta S, Veettil M, Chandran B. Kaposi's sarcoma-associated herpesvirus-positive primary effusion lymphoma tumor formation in NOD/SCID mice is inhibited by neomycin and neamine blocking angiogenin's nuclear translocation. J Virol. 2013;87:11806-20 pubmed publisher
Ghidini A, Ander C, Winqvist A, Stromberg R. An RNA modification with remarkable resistance to RNase A. Chem Commun (Camb). 2013;49:9036-8 pubmed publisher
Sundlass N, Eller C, Cui Q, Raines R. Contribution of electrostatics to the binding of pancreatic-type ribonucleases to membranes. Biochemistry. 2013;52:6304-12 pubmed publisher
Whiting C, Castillo A, Haque M, Majid D. Protective role of the endothelial isoform of nitric oxide synthase in ANG II-induced inflammatory responses in the kidney. Am J Physiol Renal Physiol. 2013;305:F1031-41 pubmed publisher
Schaafhausen M, Yang W, Centanin L, Wittbrodt J, Bosserhoff A, Fischer A, et al. Tumor angiogenesis is caused by single melanoma cells in a manner dependent on reactive oxygen species and NF-?B. J Cell Sci. 2013;126:3862-72 pubmed publisher
Nagaraju G, Ganji P, Park W, Wen J, Mahaseth H, Landry J, et al. Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1? and STAT-3. Angiogenesis. 2013;16:903-17 pubmed publisher
Gagne D, Doucet N. Structural and functional importance of local and global conformational fluctuations in the RNase A superfamily. FEBS J. 2013;280:5596-607 pubmed publisher
Ricciardolo F, Sabatini F, Sorbello V, Benedetto S, Defilippi I, Petecchia L, et al. Expression of vascular remodelling markers in relation to bradykinin receptors in asthma and COPD. Thorax. 2013;68:803-11 pubmed publisher
Gavrilenko A, Voronov D, Bochkov N. [The use of genetic angiogenesis inductors in surgical treatment of chronic lower limb ischemia]. Khirurgiia (Mosk). 2013;:25-9 pubmed
Solé M, Brandt W, Arnold U. Striking stabilization of Rana catesbeiana ribonuclease 3 by guanidine hydrochloride. FEBS Lett. 2013;587:737-42 pubmed publisher
Padhi A, Jayaram B, Gomes J. Prediction of functional loss of human angiogenin mutants associated with ALS by molecular dynamics simulations. Sci Rep. 2013;3:1225 pubmed publisher
Prapansilp P, Medana I, Mai N, Day N, Phu N, Yeo T, et al. A clinicopathological correlation of the expression of the angiopoietin-Tie-2 receptor pathway in the brain of adults with Plasmodium falciparum malaria. Malar J. 2013;12:50 pubmed publisher
Sun X, Wiedeman A, Agrawal N, Teal T, Tanaka L, Hudkins K, et al. Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice. J Immunol. 2013;190:2536-43 pubmed publisher
Chao T, Raines R. Fluorogenic label to quantify the cytosolic delivery of macromolecules. Mol Biosyst. 2013;9:339-42 pubmed publisher
Chan A, Tsai J, Lo V, Li G, Wong M, Che C. Gold-mediated selective cysteine modification of peptides using allenes. Chem Commun (Camb). 2013;49:1428-30 pubmed publisher
Shek Y, Chalikian T. Interactions of glycine betaine with proteins: insights from volume and compressibility measurements. Biochemistry. 2013;52:672-80 pubmed publisher
Granner T, Maloney S, Antecka E, Correa J, Burnier M. 3,4 dihydroxyphenyl ethanol reduces secretion of angiogenin in human retinal pigment epithelial cells. Br J Ophthalmol. 2013;97:371-4 pubmed publisher
Zhai Y, Winter R. Effect of molecular crowding on the temperature-pressure stability diagram of ribonuclease A. Chemphyschem. 2013;14:386-93 pubmed publisher
Kong Y, Chen J, Gao F, Brydson R, Johnson B, Heath G, et al. Near-infrared fluorescent ribonuclease-A-encapsulated gold nanoclusters: preparation, characterization, cancer targeting and imaging. Nanoscale. 2013;5:1009-17 pubmed publisher
Kuwahara A, Jinnin M, Makino T, Kajihara I, Makino K, Honda N, et al. Angiogenin expression in the sera and skin of patients with rheumatic diseases. Biosci Trends. 2012;6:229-33 pubmed
Chen X, Henschke L, Wu Q, Muthoosamy K, Neumann B, Weil T. Site-selective azide incorporation into endogenous RNase A via a "chemistry" approach. Org Biomol Chem. 2013;11:353-61 pubmed publisher
Iyer S, Holloway D, Acharya K. Crystal structures of murine angiogenin-2 and -3-probing 'structure--function' relationships amongst angiogenin homologues. FEBS J. 2013;280:302-18 pubmed publisher
van Blitterswijk M, Vlam L, van Es M, van der Pol W, Hennekam E, Dooijes D, et al. Genetic overlap between apparently sporadic motor neuron diseases. PLoS ONE. 2012;7:e48983 pubmed publisher
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Thiyagarajan N, Ferguson R, Subramanian V, Acharya K. Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons. Nat Commun. 2012;3:1121 pubmed publisher
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Huang S, Yang N, Liu Y, Gao J, Huang T, Hu L, et al. Grape seed proanthocyanidins inhibit colon cancer-induced angiogenesis through suppressing the expression of VEGF and Ang1. Int J Mol Med. 2012;30:1410-6 pubmed publisher
Li C, Lin Q, Wang J, Shen L, Ma G, Su Z, et al. Preparation, structural analysis and bioactivity of ribonuclease A-albumin conjugate: tetra-conjugation or PEG as the linker. J Biotechnol. 2012;162:283-8 pubmed publisher
Misra P, Kishore N. Glycine betaine: a widely reported osmolyte induces differential and selective conformational stability and enhances aggregation in some proteins in the presence of surfactants. Biopolymers. 2012;97:933-49 pubmed publisher
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Laparra J, Sanz Y. Bifidobacteria inhibit the inflammatory response induced by gliadins in intestinal epithelial cells via modifications of toxic peptide generation during digestion. J Cell Biochem. 2010;109:801-7 pubmed publisher
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Beard J, Razzell W. PURIFICATION OF ALKALINE RIBONUCLEASE II FROM MITOCHONDRIAL AND SOLUBLE FRACTIONS OF LIVER. J Biol Chem. 1964;239:4186-93 pubmed
Joseph McCarthy D, Fedorov A, Almo S. Comparison of experimental and computational functional group mapping of an RNase A structure: implications for computer-aided drug design. Protein Eng. 1996;9:773-80 pubmed
Cannistraro V, Kennell D. Purification and characterization of ribonuclease M and mRNA degradation in Escherichia coli. Eur J Biochem. 1989;181:363-70 pubmed
product information
Catalog Number :
R4875
Product Name :
Ribonuclease A from bovine pancreas
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
Type I-A, powder, ≥60% RNase A basis (SDS-PAGE),
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA