This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Raloxifene hydrochloride
catalog :
R1402
citations: 51
Reference
D amour J, Magagna Poveda A, Moretto J, Friedman D, Lafrancois J, Pearce P, et al. Interictal spike frequency varies with ovarian cycle stage in a rat model of epilepsy. Exp Neurol. 2015;269:102-19 pubmed publisher
Bartonkova I, Novotna A, Dvorak Z. Novel stably transfected human reporter cell line AIZ-AR as a tool for an assessment of human androgen receptor transcriptional activity. PLoS ONE. 2015;10:e0121316 pubmed publisher
Vidugiriene J, Leippe D, Sobol M, Vidugiris G, Zhou W, Meisenheimer P, et al. Bioluminescent cell-based NAD(P)/NAD(P)H assays for rapid dinucleotide measurement and inhibitor screening. Assay Drug Dev Technol. 2014;12:514-26 pubmed publisher
Nichols H, DeRoo L, Scharf D, Sandler D. Risk-benefit profiles of women using tamoxifen for chemoprevention. J Natl Cancer Inst. 2015;107:354 pubmed publisher
Ishihara Y, Itoh K, Ishida A, Yamazaki T. Selective estrogen-receptor modulators suppress microglial activation and neuronal cell death via an estrogen receptor-dependent pathway. J Steroid Biochem Mol Biol. 2015;145:85-93 pubmed publisher
Hermansen L, Sørensen M, Barckman J, Bechtold J, Søballe K, Baas J. Incorporation of raloxifene-impregnated allograft around orthopedic titanium implants impairs early fixation but improves new bone formation. Acta Orthop. 2015;86:127-33 pubmed publisher
Abdelazim I, Abdelrazak K, Al Kadi M, Yehia A, Nusair B, Faza M. Effect of raloxifene hydrochloride on bone mineral density and bone turnover in Kuwaiti postmenopausal women with osteoporosis. Arch Osteoporos. 2014;9:189 pubmed publisher
Inoue K, Mizuo H, Kawaguchi S, Fukuda K, Kusano K, Yoshimura T. Oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase. Drug Metab Dispos. 2014;42:1326-33 pubmed publisher
Tran T, Ramasamy T, Cho H, Kim Y, Poudel B, Choi H, et al. Formulation and optimization of raloxifene-loaded solid lipid nanoparticles to enhance oral bioavailability. J Nanosci Nanotechnol. 2014;14:4820-31 pubmed
Fontana R, Della Torre S, Meda C, Longo A, Eva C, Maggi A. Estrogen replacement therapy regulation of energy metabolism in female mouse hypothalamus. Endocrinology. 2014;155:2213-21 pubmed publisher
. Experts add second drug to breast cancer prevention regimen. Harv Womens Health Watch. 2013;21:8 pubmed
. Summaries for patients. Using medications to decrease the risk for breast cancer in women: recommendations from the U.S. Preventive Services Task Force. Ann Intern Med. 2013;159:I-28 pubmed
Pinkerton J, Thomas S. Use of SERMs for treatment in postmenopausal women. J Steroid Biochem Mol Biol. 2014;142:142-54 pubmed publisher
Moyer V. Medications to decrease the risk for breast cancer in women: recommendations from the U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2013;159:698-708 pubmed publisher
Wise J. NICE recommends preventive drugs for breast cancer. BMJ. 2013;346:f4116 pubmed publisher
Grove E, Abrahamsen B, Vestergaard P. Heart failure in patients treated with bisphosphonates. J Intern Med. 2013;274:342-50 pubmed publisher
Unkila M, Kari S, Yatkin E, Lammintausta R. Vaginal effects of ospemifene in the ovariectomized rat preclinical model of menopause. J Steroid Biochem Mol Biol. 2013;138:107-15 pubmed publisher
Kumar P, Song Z. Identification of raloxifene as a novel CB2 inverse agonist. Biochem Biophys Res Commun. 2013;435:76-81 pubmed publisher
McCarthy M. Breast cancer drugs should be offered to healthy but high risk women, US panel concludes. BMJ. 2013;346:f2499 pubmed publisher
Nelson H, Smith M, Griffin J, Fu R. Use of medications to reduce risk for primary breast cancer: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2013;158:604-14 pubmed publisher
Mendoza Edroso C, Sánchez Garrido Lestache N, López Picado A. [Postmenopausal osteoporosis: Primary prevention or excessive use of medications]. Semergen. 2013;39:123-9 pubmed publisher
Foster S, Shi N, Curkendall S, Stock J, Chu B, Burge R, et al. Fractures in women treated with raloxifene or alendronate: a retrospective database analysis. BMC Womens Health. 2013;13:15 pubmed publisher
Daniels L, Grady D, Mosca L, Collins P, Mitlak B, Amewou Atisso M, et al. Is diabetes mellitus a heart disease equivalent in women? Results from an international study of postmenopausal women in the Raloxifene Use for the Heart (RUTH) Trial. Circ Cardiovasc Qual Outcomes. 2013;6:164-70 pubmed publisher
Budoff M. Diabetes mellitus in women can be RUTHless: lessons from the Raloxifene Use for The Heart (RUTH) Trial. Circ Cardiovasc Qual Outcomes. 2013;6:137-8 pubmed publisher
Liu S, Han S, Smith C. Cooperative activation of gene expression by agonists and antagonists mediated by estrogen receptor heteroligand dimer complexes. Mol Pharmacol. 2013;83:1066-77 pubmed publisher
Kavas A, Cagatay S, Banerjee S, Keskin D, Tezcaner A. Potential of Raloxifene in reversing osteoarthritis-like alterations in rat chondrocytes: an in vitro model study. J Biosci. 2013;38:135-47 pubmed
Briongos L, Sañudo S, Garcia Alonso M, Ruiz Mambrilla M, Duenas Laita A, Perez Castrillon J. Treatment of osteoporosis and hip fractures in a Spanish health area. Eur Rev Med Pharmacol Sci. 2013;17:266-8 pubmed
Cook I, Wang T, Almo S, Kim J, Falany C, Leyh T. Testing the sulfotransferase molecular pore hypothesis. J Biol Chem. 2013;288:8619-26 pubmed publisher
Schaid D, Jenkins G, Ingle J, Weinshilboum R. Two-phase designs to follow-up genome-wide association signals with DNA resequencing studies. Genet Epidemiol. 2013;37:229-38 pubmed publisher
Nishi Y, Satoh M, Nagasu H, Kadoya H, Ihoriya C, Kidokoro K, et al. Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status. Kidney Int. 2013;83:662-73 pubmed publisher
Tran T, Poudel B, Marasini N, Woo J, Choi H, Yong C, et al. Development of raloxifene-solid dispersion with improved oral bioavailability via spray-drying technique. Arch Pharm Res. 2013;36:86-93 pubmed publisher
Ando H, Otoda T, Ookami H, Nagai Y, Inano A, Takamura T, et al. Dosing time-dependent effect of raloxifene on plasma plasminogen activator inhibitor-1 concentrations in post-menopausal women with osteoporosis. Clin Exp Pharmacol Physiol. 2013;40:227-32 pubmed publisher
Tran T, Poudel B, Marasini N, Chi S, Choi H, Yong C, et al. Preparation and evaluation of raloxifene-loaded solid dispersion nanoparticle by spray-drying technique without an organic solvent. Int J Pharm. 2013;443:50-7 pubmed publisher
. Breast cancer facts. J Okla State Med Assoc. 2012;105:411-2 pubmed
Yadav A, Carey E. Osteoporosis in chronic liver disease. Nutr Clin Pract. 2013;28:52-64 pubmed publisher
Takeda S, Sakai S, Shiraishi A, Koike N, Mihara M, Endo K. Combination treatment with eldecalcitol (ED-71) and raloxifene improves bone mechanical strength by suppressing bone turnover and increasing bone mineral density in ovariectomized rats. Bone. 2013;53:167-73 pubmed publisher
Westphal C, Schubert C, Prelle K, Penkalla A, Fliegner D, Petrov G, et al. Effects of estrogen, an ER? agonist and raloxifene on pressure overload induced cardiac hypertrophy. PLoS ONE. 2012;7:e50802 pubmed publisher
Ismailoglu O, Oral B, Sutcu R, Kara Y, Tomruk O, Demir N. Neuroprotective effects of raloxifene on experimental spinal cord injury in rats. Am J Med Sci. 2013;345:39-44 pubmed publisher
Martins Maciel E, Campos L, Salgueiro Pagadigorria C, Bracht A, Ishii Iwamoto E. Raloxifene affects fatty acid oxidation in livers from ovariectomized rats by acting as a pro-oxidant agent. Toxicol Lett. 2013;217:82-9 pubmed publisher
Sadhu K, Eierhoff T, Römer W, Winssinger N. Photoreductive uncaging of fluorophore in response to protein oligomers by templated reaction in vitro and in cellulo. J Am Chem Soc. 2012;134:20013-6 pubmed publisher
Vlachopoulos C, Xaplanteris P, Stefanadis C. Raloxifene, arterial function and Ockham's razor. Vascul Pharmacol. 2013;58:1-2 pubmed publisher
Rodrigues Junior D, Lopes Costa P, dos Santos A, da Silva B. Effects of tamoxifen and raloxifene on body and uterine weights of rats in persistent estrus. Clin Exp Obstet Gynecol. 2012;39:362-4 pubmed
Coopey S, Mazzola E, Buckley J, Sharko J, Belli A, Kim E, et al. The role of chemoprevention in modifying the risk of breast cancer in women with atypical breast lesions. Breast Cancer Res Treat. 2012;136:627-33 pubmed publisher
Khedr N, El Ashmawy N, El Bahrawy H, Haggag A, El Abd E. Modulation of bone turnover in orchidectomized rats treated with raloxifene and risedronate. Fundam Clin Pharmacol. 2013;27:526-34 pubmed publisher
Barreto G, Santos Galindo M, Diz Chaves Y, Pernia O, Carrero P, Azcoitia I, et al. Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones. Endocrinology. 2009;150:5010-5 pubmed publisher
Kobayashi H, Hamaya E. [Raloxifene hydrochloride (Evista Tablet 60 mg) for postmenopausal osteoporosis: mode of action and clinical efficacy]. Nihon Yakurigaku Zasshi. 2005;125:37-48 pubmed
Itabashi A. [Raloxifene hydrochloride]. Nihon Rinsho. 2004;62 Suppl 2:528-35 pubmed
Saitta A, Morabito N, Frisina N, Cucinotte D, Corrado F, D Anna R, et al. Cardiovascular effects of raloxifene hydrochloride. Cardiovasc Drug Rev. 2001;19:57-74 pubmed
Snyder K, Sparano N, Malinowski J. Raloxifene hydrochloride. Am J Health Syst Pharm. 2000;57:1669-75; quiz 1676-8 pubmed
Fitzpatrick S, Berrodin T, Jenkins S, Sindoni D, Deecher D, Frail D. Effect of estrogen agonists and antagonists on induction of progesterone receptor in a rat hypothalamic cell line. Endocrinology. 1999;140:3928-37 pubmed
Khovidhunkit W, Shoback D. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999;130:431-9 pubmed
product information
Catalog Number :
R1402
Product Name :
Raloxifene hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA