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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Quinidine
catalog :
Q3625
citations: 135
Reference
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Milligan C, Li M, Gazina E, Heron S, Nair U, Trager C, et al. KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine. Ann Neurol. 2014;75:581-90 pubmed publisher
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Boulé S, Kouakam C, Brigadeau F. Very prolonged episode of self-terminating ventricular fibrillation in a patient with Brugada syndrome. Can J Cardiol. 2013;29:1742.e1-3 pubmed publisher
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Pellegrino P, Di Biase M, Brunetti N. Quinidine for the management of electrical storm in an old patient with Brugada syndrome and syncope. Acta Cardiol. 2013;68:201-3 pubmed
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Viskin S, Wilde A, Guevara Valdivia M, Daoulah A, Krahn A, Zipes D, et al. Quinidine, a life-saving medication for Brugada syndrome, is inaccessible in many countries. J Am Coll Cardiol. 2013;61:2383-7 pubmed publisher
Jain R, Dhanjai -. Nano graphene based sensor for antiarrhythmic agent quinidine in solubilized system. Colloids Surf B Biointerfaces. 2013;105:278-83 pubmed publisher
Martinkova M, Kubickova B, Stiborova M. Effects of cytochrome P450 inhibitors on peroxidase activity. Neuro Endocrinol Lett. 2012;33 Suppl 3:33-40 pubmed
Guo Q, Zhao J. Highly enantioselective three-component direct Mannich reactions of unfunctionalized ketones catalyzed by bifunctional organocatalysts. Org Lett. 2013;15:508-11 pubmed publisher
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El Harchi A, Melgari D, Zhang Y, Zhang H, Hancox J. Action potential clamp and pharmacology of the variant 1 Short QT Syndrome T618I hERG K⁺ channel. PLoS ONE. 2012;7:e52451 pubmed publisher
Lai P, Walters J. Azithromycin kills invasive Aggregatibacter actinomycetemcomitans in gingival epithelial cells. Antimicrob Agents Chemother. 2013;57:1347-51 pubmed publisher
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Kessler S, Vlimant M, Guerin P. The sugar meal of the African malaria mosquito Anopheles gambiae and how deterrent compounds interfere with it: a behavioural and neurophysiological study. J Exp Biol. 2013;216:1292-306 pubmed publisher
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Yang T, Smith J, Leake B, Sanders C, Meiler J, Roden D. An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1. Mol Pharmacol. 2013;83:481-9 pubmed publisher
Ishii K, Norota I, Obara Y. Endocytic regulation of voltage-dependent potassium channels in the heart. J Pharmacol Sci. 2012;120:264-9 pubmed
Sequiera G, Mehta A, Ooi T, Shim W. Ontogenic development of cardiomyocytes derived from transgene-free human induced pluripotent stem cells and its homology with human heart. Life Sci. 2013;92:63-71 pubmed publisher
Pandey S, Dwivedi H, Singh S, Siddiqui W, Tripathi R. Antimalarial interaction of quinine and quinidine with clarithromycin. Parasitology. 2013;140:406-13 pubmed publisher
Barot M, Gokulgandhi M, Pal D, Mitra A. Mitochondrial localization of P-glycoprotein and peptide transporters in corneal epithelial cells--novel strategies for intracellular drug targeting. Exp Eye Res. 2013;106:47-54 pubmed publisher
Gorka A, Sherlach K, De Dios A, Roepe P. Relative to quinine and quinidine, their 9-epimers exhibit decreased cytostatic activity and altered heme binding but similar cytocidal activity versus Plasmodium falciparum. Antimicrob Agents Chemother. 2013;57:365-74 pubmed publisher
Wu S, Zeng W, Wang Q, Chen F. Asymmetric trifluoromethylation of aromatic aldehydes by cooperative catalysis with (IPr)CuF and quinidine-derived quaternary ammonium salt. Org Biomol Chem. 2012;10:9334-7 pubmed publisher
Cros C, Skinner M, Moors J, Lainee P, Valentin J. Detecting drug-induced prolongation of the QRS complex: new insights for cardiac safety assessment. Toxicol Appl Pharmacol. 2012;265:200-8 pubmed publisher
Belhassen B. Is quinidine the ideal drug for brugada syndrome?. Heart Rhythm. 2012;9:2001-2 pubmed publisher
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Marquez M, Bonny A, Hernández Castillo E, De Sisti A, Gómez Flores J, Nava S, et al. Long-term efficacy of low doses of quinidine on malignant arrhythmias in Brugada syndrome with an implantable cardioverter-defibrillator: a case series and literature review. Heart Rhythm. 2012;9:1995-2000 pubmed publisher
Phillips K, Hirsch G, Epstein D, Preston K. Cardiac complications of unwitting co-injection of quinine/quinidine with heroin in an intravenous drug user. J Gen Intern Med. 2012;27:1722-5 pubmed publisher
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product information
Catalog Number :
Q3625
Product Name :
Quinidine
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
anhydrous
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA