This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Varenicline tartrate
catalog :
PZ0004
citations: 28
Reference
Chuang Y, Lee C, Lin C, Liu C, Huang S, Lee J, et al. An Integrated Genomic Strategy to Identify CHRNB4 as a Diagnostic/Prognostic Biomarker for Targeted Therapy in Head and Neck Cancer. Cancers (Basel). 2020;12: pubmed publisher
Park J, Kim K, Son H, Jung J, Park J. Pharmacokinetic comparisons of two different varenicline formulations in humans: Varenicline tartrate versus varenicline oxalate
. Int J Clin Pharmacol Ther. 2020;58:121-127 pubmed publisher
Zaccarelli Magalhães J, Sandini T, de Abreu G, Petrocelli B, Moreira N, Reis Silva T, et al. Prolonged exposure of rats to varenicline increases anxiety and alters serotonergic system, but has no effect on memory. Pharmacol Biochem Behav. 2019;181:1-8 pubmed publisher
Waeiss R, Knight C, Hauser S, Pratt L, McBride W, Rodd Z. Therapeutic challenges for concurrent ethanol and nicotine consumption: naltrexone and varenicline fail to alter simultaneous ethanol and nicotine intake by female alcohol-preferring (P) rats. Psychopharmacology (Berl). 2019;: pubmed publisher
Kazan T, Charntikov S. Individual differences in responding to bupropion or varenicline in a preclinical model of nicotine self-administration vary according to individual demand for nicotine. Neuropharmacology. 2019;148:139-150 pubmed publisher
Mizoguchi H, Wang T, Kusaba M, Fukumoto K, Yamada K. Nicotine and varenicline ameliorate changes in reward-based choice strategy and altered decision-making in methamphetamine-treated rats. Behav Brain Res. 2019;359:935-941 pubmed publisher
Holmes N, Pan J, Davis A, Panayi M, Clemens K. Rats choose high doses of nicotine in order to compensate for changes in its price and availability. Addict Biol. 2019;24:849-859 pubmed publisher
Tan R, Bolukbaşi Hatip F, Açikalin Ö, Yamauchi A, Kataoka Y, Hatip Al Khatib I. Effect of varenicline on behavioral deficits in a rat model of Parkinson's disease induced by unilateral 6-hydroxydopamine lesion of substantia nigra. Behav Pharmacol. 2018;29:327-335 pubmed publisher
Kamens H, Silva C, Peck C, Miller C. Varenicline modulates ethanol and saccharin consumption in adolescent male and female C57BL/6J mice. Brain Res Bull. 2018;138:20-25 pubmed publisher
Kurosawa T, Higuchi K, Okura T, Kobayashi K, Kusuhara H, Deguchi Y. Involvement of Proton-Coupled Organic Cation Antiporter in Varenicline Transport at Blood-Brain Barrier of Rats and in Human Brain Capillary Endothelial Cells. J Pharm Sci. 2017;106:2576-2582 pubmed publisher
Piestansky J, Maráková K, Galba J, Kovac A, Mikus P. Comparison of hydrodynamically closed two-dimensional capillary electrophoresis coupled with ultraviolet detection and hydrodynamically open capillary electrophoresis hyphenated with mass spectrometry in the bioanalysis of varenicline. J Sep Sci. 2017;40:2292-2303 pubmed publisher
Ohmura Y, Sasamori H, Tsutsui Kimura I, Izumi T, Yoshida T, Yoshioka M. Varenicline provokes impulsive action by stimulating ?4?2 nicotinic acetylcholine receptors in the infralimbic cortex in a nicotine exposure status-dependent manner. Pharmacol Biochem Behav. 2017;154:1-10 pubmed publisher
Jackson A, Silk S, Buhidma Y, Shoaib M. Varenicline, the clinically effective smoking cessation agent, restores probabilistic response reversal performance during withdrawal from nicotine. Addict Biol. 2017;22:1316-1328 pubmed publisher
Clemens K, Lay B, Holmes N. Extended nicotine self-administration increases sensitivity to nicotine, motivation to seek nicotine and the reinforcing properties of nicotine-paired cues. Addict Biol. 2017;22:400-410 pubmed publisher
Terry A, Plagenhoef M, Callahan P. Effects of the nicotinic agonist varenicline on the performance of tasks of cognition in aged and middle-aged rhesus and pigtail monkeys. Psychopharmacology (Berl). 2016;233:761-71 pubmed publisher
de Bejczy A, Löf E, Walther L, Guterstam J, Hammarberg A, Asanovska G, et al. Varenicline for treatment of alcohol dependence: a randomized, placebo-controlled trial. Alcohol Clin Exp Res. 2015;39:2189-99 pubmed publisher
Marks M, O Neill H, Wynalda Camozzi K, Ortiz N, Simmons E, Short C, et al. Chronic treatment with varenicline changes expression of four nAChR binding sites in mice. Neuropharmacology. 2015;99:142-55 pubmed publisher
Lambert C, Philpot R, Engberg M, Johns B, Wecker L. Analysis of gait in rats with olivocerebellar lesions and ability of the nicotinic acetylcholine receptor agonist varenicline to attenuate impairments. Behav Brain Res. 2015;291:342-350 pubmed publisher
Randall P, Jaramillo A, Frisbee S, Besheer J. The role of varenicline on alcohol-primed self-administration and seeking behavior in rats. Psychopharmacology (Berl). 2015;232:2443-54 pubmed publisher
Price K, Lillestol R, Ulens C, Lummis S. Varenicline Interactions at the 5-HT3 Receptor Ligand Binding Site are Revealed by 5-HTBP. ACS Chem Neurosci. 2015;6:1151-7 pubmed publisher
Hall B, Slade S, Wells C, Rose J, Levin E. Bupropion-varenicline interactions and nicotine self-administration behavior in rats. Pharmacol Biochem Behav. 2015;130:84-9 pubmed publisher
Gubner N, McKinnon C, Phillips T. Effects of varenicline on ethanol-induced conditioned place preference, locomotor stimulation, and sensitization. Alcohol Clin Exp Res. 2014;38:3033-42 pubmed publisher
Panlilio L, Hogarth L, Shoaib M. Concurrent access to nicotine and sucrose in rats. Psychopharmacology (Berl). 2015;232:1451-60 pubmed publisher
Guy E, Fisher D, Higgins G, Fletcher P. Examination of the effects of varenicline, bupropion, lorcaserin, or naltrexone on responding for conditioned reinforcement in nicotine-exposed rats. Behav Pharmacol. 2014;25:775-83 pubmed publisher
Schassburger R, Levin M, Weaver M, Palmatier M, Caggiula A, Donny E, et al. Differentiating the primary reinforcing and reinforcement-enhancing effects of varenicline. Psychopharmacology (Berl). 2015;232:975-83 pubmed publisher
Tsai P, Bake S, Balaraman S, Rawlings J, Holgate R, Dubois D, et al. MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells. Biol Open. 2014;3:741-58 pubmed publisher
Goktalay T, Buyukuysal S, Uslu G, Coskun A, Yorgancioglu A, Kayir H, et al. Varenicline disrupts prepulse inhibition only in high-inhibitory rats. Prog Neuropsychopharmacol Biol Psychiatry. 2014;53:54-60 pubmed publisher
Costello M, Reynaga D, Mojica C, Zaveri N, Belluzzi J, Leslie F. Comparison of the reinforcing properties of nicotine and cigarette smoke extract in rats. Neuropsychopharmacology. 2014;39:1843-51 pubmed publisher
product information
Catalog Number :
PZ0004
Product Name :
Varenicline tartrate
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA