This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Phosphodiesterase II from bovine spleen
catalog :
P9041
citations: 31
Reference
Kang B, Miyauchi K, Matuszewski M, D Almeida G, Rubio M, Alfonzo J, et al. Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs. Nucleic Acids Res. 2017;45:2124-2136 pubmed publisher
Angelone T, Quintieri A, Pasqua T, Gentile S, Tota B, Mahata S, et al. Phosphodiesterase type-2 and NO-dependent S-nitrosylation mediate the cardioinhibition of the antihypertensive catestatin. Am J Physiol Heart Circ Physiol. 2012;302:H431-42 pubmed publisher
Keravis T, Lugnier C. Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments. Br J Pharmacol. 2012;165:1288-305 pubmed publisher
Pav O, Kóšiová I, Barvik I, Pohl R, Budesinsky M, Rosenberg I. Synthesis of oligoribonucleotides with phosphonate-modified linkages. Org Biomol Chem. 2011;9:6120-6 pubmed publisher
Upadhayaya R, Deshpande S, Li Q, Kardile R, Sayyed A, Kshirsagar E, et al. Carba-LNA-5MeC/A/G/T modified oligos show nucleobase-specific modulation of 3'-exonuclease activity, thermodynamic stability, RNA selectivity, and RNase H elicitation: synthesis and biochemistry. J Org Chem. 2011;76:4408-31 pubmed publisher
Yoshida R, Miyashita K, Inoue M, Shimamoto A, Yan Z, Egashira A, et al. Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer. Eur J Hum Genet. 2011;19:320-5 pubmed publisher
Liu Y, Xu J, Karimiahmadabadi M, Zhou C, Chattopadhyaya J. Synthesis of 2',4'-propylene-bridged (carba-ENA) thymidine and its analogues: the engineering of electrostatic and steric effects at the bottom of the minor groove for nuclease and thermodynamic stabilities and elicitation of RNase H. J Org Chem. 2010;75:7112-28 pubmed publisher
Rubinson E, Gowda A, Spratt T, Gold B, Eichman B. An unprecedented nucleic acid capture mechanism for excision of DNA damage. Nature. 2010;468:406-11 pubmed publisher
Skarphedinsdottir H, Hallgrimsson G, Hansson T, Hägerroth P, Liewenborg B, Tjärnlund U, et al. Genotoxicity in herring gulls (Larus argentatus) in Sweden and Iceland. Mutat Res. 2010;702:24-31 pubmed publisher
Wojcik M, Stec W. The effect of divalent cations on the catalytic activity of the human plasma 3'-exonuclease. Biometals. 2010;23:1113-21 pubmed publisher
Ramanujam R, Naqvi N. PdeH, a high-affinity cAMP phosphodiesterase, is a key regulator of asexual and pathogenic differentiation in Magnaporthe oryzae. PLoS Pathog. 2010;6:e1000897 pubmed publisher
Thayer J, Puri N, Burnett C, Hail M, Rao S. Identification of RNA linkage isomers by anion exchange purification with electrospray ionization mass spectrometry of automatically desalted phosphodiesterase-II digests. Anal Biochem. 2010;399:110-7 pubmed publisher
Gao H, Liu Y, Rumley M, Yuan H, Mao B. Sequence confirmation of chemically modified RNAs using exonuclease digestion and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom. 2009;23:3423-30 pubmed publisher
Masood A, Huang Y, Hajjhussein H, Xiao L, Li H, Wang W, et al. Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling. J Pharmacol Exp Ther. 2009;331:690-9 pubmed publisher
Cockerham R, Puche A, Munger S. Heterogeneous sensory innervation and extensive intrabulbar connections of olfactory necklace glomeruli. PLoS ONE. 2009;4:e4657 pubmed publisher
Sauer S, Reinhardt R, Lehrach H, Gut I. Single-nucleotide polymorphisms: analysis by mass spectrometry. Nat Protoc. 2006;1:1761-71 pubmed
Honcharenko D, Barman J, Varghese O, Chattopadhyaya J. Comparison of the RNase H cleavage kinetics and blood serum stability of the north-conformationally constrained and 2'-alkoxy modified oligonucleotides. Biochemistry. 2007;46:5635-46 pubmed
Linder J, Bruder S, Schultz A, Schultz J. Changes in purine specificity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2. FEBS J. 2007;274:1514-23 pubmed
Diederen R, La Heij E, Markerink van Ittersum M, Kijlstra A, Hendrikse F, de Vente J. Selective blockade of phosphodiesterase types 2, 5 and 9 results in cyclic 3'5' guanosine monophosphate accumulation in retinal pigment epithelium cells. Br J Ophthalmol. 2007;91:379-84 pubmed
Liu X, Hou J, Liu J. Chlamydial DNA polymerase I can bypass lesions in vitro. Biochem Biophys Res Commun. 2006;345:1083-91 pubmed
Nazarkina Z, Pyshnyi D, Pyshnaya I, Lavrik O, Khodyreva S. Use of modified flap structures for study of base excision repair proteins. Biochemistry (Mosc). 2005;70:1327-34 pubmed
Saneyoshi H, Seio K, Sekine M. A general method for the synthesis of 2'-O-cyanoethylated oligoribonucleotides having promising hybridization affinity for DNA and RNA and enhanced nuclease resistance. J Org Chem. 2005;70:10453-60 pubmed
Feng H, Dong L, Klutz A, Aghaebrahim N, Cao W. Defining amino acid residues involved in DNA-protein interactions and revelation of 3'-exonuclease activity in endonuclease V. Biochemistry. 2005;44:11486-95 pubmed
Juan Fita M, Vargas M, Hernandez J. The phosphodiesterase 3 inhibitor cilostamide enhances inotropic responses to glucagon but not to dobutamine in rat ventricular myocardium. Eur J Pharmacol. 2005;512:207-13 pubmed
Gupta R, Beck J, Sheil M, Ralph S. Identification of bifunctional GA and AG intrastrand crosslinks formed between cisplatin and DNA. J Inorg Biochem. 2005;99:552-9 pubmed
Snyder P, Esselstyn J, Loughney K, Wolda S, Florio V. The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis. J Lipid Res. 2005;46:494-503 pubmed
Boess F, Hendrix M, van der Staay F, Erb C, Schreiber R, van Staveren W, et al. Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance. Neuropharmacology. 2004;47:1081-92 pubmed
Fock E, Lavrova E, Bachteeva V, Chernigovskaya E, Parnova R. Nitric oxide inhibits arginine-vasotocin-induced increase of water osmotic permeability in frog urinary bladder. Pflugers Arch. 2004;448:197-203 pubmed
Maurice D. Dynamic regulation of cAMP signaling by cGMP in the cardiovascular system: roles of phosphodiesterase 2 and phosphodiesterase 3 enzymes. Proc West Pharmacol Soc. 2003;46:32-6 pubmed
Bamford D, Mindich L. Characterization of the DNA-protein complex at the termini of the bacteriophage PRD1 genome. J Virol. 1984;50:309-15 pubmed
Balsamo J, Lilien J. N-cadherin is stably associated with and is an acceptor for a cell surface N-acetylgalactosaminylphosphotransferase. J Biol Chem. 1990;265:2923-8 pubmed
product information
Catalog Number :
P9041
Product Name :
Phosphodiesterase II from bovine spleen
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
lyophilized powder, ?5.0 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA