product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-p53 antibody produced in mouse
catalog :
P8999
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DO-7
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; loading ...; fig 5a
Mehta N, Lyon J, Patil K, Mokarram N, Kim C, Bellamkonda R. Bacterial Carriers for Glioblastoma Therapy. Mol Ther Oncolytics. 2017;4:1-17 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Macritchie N, Volpert G, Al Washih M, Watson D, Futerman A, Kennedy S, et al. Effect of the sphingosine kinase 1 selective inhibitor, PF-543 on arterial and cardiac remodelling in a hypoxic model of pulmonary arterial hypertension. Cell Signal. 2016;28:946-55 pubmed publisher
  • western blot; human; loading ...; fig 6
McNaughton M, Pitman M, Pitson S, Pyne N, Pyne S. Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells. Oncotarget. 2016;7:16663-75 pubmed publisher
  • western blot; human
Rodríguez Sureda V, Vilches Ã, Sánchez O, Audí L, Domínguez C. Intracellular oxidant activity, antioxidant enzyme defense system, and cell senescence in fibroblasts with trisomy 21. Oxid Med Cell Longev. 2015;2015:509241 pubmed publisher
Barabutis N, Dimitropoulou C, Gregory B, Catravas J. Wild-type p53 enhances endothelial barrier function by mediating RAC1 signalling and RhoA inhibition. J Cell Mol Med. 2018;22:1792-1804 pubmed publisher
Barabutis N, Khangoora V, Marik P, Catravas J. Hydrocortisone and Ascorbic Acid Synergistically Prevent and Repair Lipopolysaccharide-Induced Pulmonary Endothelial Barrier Dysfunction. Chest. 2017;152:954-962 pubmed publisher
Oktay Y, Ülgen E, Can Ã, Akyerli C, Yüksel Å, Erdemgil Y, et al. IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. Sci Rep. 2016;6:27569 pubmed publisher
Harrington B, He Y, Davies C, Wallace S, Adams M, Beaven E, et al. Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer. Br J Cancer. 2016;114:417-26 pubmed publisher
Shi H, Fu C, Wang W, Li Y, Du S, Cao R, et al. The FGF-1-specific single-chain antibody scFv1C9 effectively inhibits breast cancer tumour growth and metastasis. J Cell Mol Med. 2014;18:2061-70 pubmed publisher
product information
Product No. :
P8999
Product Name :
Monoclonal Anti-p53 antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
DO-7
Applications/Description :
Suitable for immunocytochemistry; western blot: 0.1-0.2 μg/mL using human A431; indirect ELISA; immunoprecipitation (IP); immunohistochemistry
Species Reactivity :
human
Isotype :
IgG2b
Concentration :
~2 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA