This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Psoralen
catalog :
P8399
citations: 67
Reference
Li N, Wang J, Wallace S, Chen J, Zhou J, D Andrea A. Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair. Nucleic Acids Res. 2020;48:3014-3028 pubmed publisher
Ayil Gutiérrez B, Villegas Mendoza J, Santes Hernndez Z, Paz González A, Mireles Martínez M, Rosas García N, et al. Ruta graveolens Extracts and Metabolites against Spodoptera frugiperda. Nat Prod Commun. 2015;10:1955-8 pubmed
Bellare P, Dufresne A, Ganem D. Inefficient Codon Usage Impairs mRNA Accumulation: the Case of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2015;89:7097-107 pubmed publisher
Xie J, Kim H, Moreau L, Puhalla S, Garber J, Al Abo M, et al. RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway. J Clin Invest. 2015;125:1523-32 pubmed publisher
Zellweger R, Dalcher D, Mutreja K, Berti M, Schmid J, Herrador R, et al. Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells. J Cell Biol. 2015;208:563-79 pubmed publisher
Tree J, Hall G, Pearson G, Rayner E, Graham V, Steeds K, et al. Sequence of pathogenic events in cynomolgus macaques infected with aerosolized monkeypox virus. J Virol. 2015;89:4335-44 pubmed publisher
Barr J, Jones J, Oberlies N, Paine M. Inhibition of human aldehyde oxidase activity by diet-derived constituents: structural influence, enzyme-ligand interactions, and clinical relevance. Drug Metab Dispos. 2015;43:34-41 pubmed publisher
Ainslie G, Wolf K, Li Y, Connolly E, Scarlett Y, Hull J, et al. Assessment of a candidate marker constituent predictive of a dietary substance-drug interaction: case study with grapefruit juice and CYP3A4 drug substrates. J Pharmacol Exp Ther. 2014;351:576-84 pubmed publisher
Paradisi A, Tabolli S, Didona B, Sobrino L, Russo N, Abeni D. Markedly reduced incidence of melanoma and nonmelanoma skin cancer in a nonconcurrent cohort of 10,040 patients with vitiligo. J Am Acad Dermatol. 2014;71:1110-6 pubmed publisher
Heipertz E, Davies M, Lin E, Norbury C. Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation. J Immunol. 2014;193:4169-77 pubmed publisher
Humme D, Nast A, Erdmann R, Vandersee S, Beyer M. Systematic review of combination therapies for mycosis fungoides. Cancer Treat Rev. 2014;40:927-33 pubmed publisher
Arnoldi F, De Lorenzo G, Mano M, Schraner E, Wild P, Eichwald C, et al. Rotavirus increases levels of lipidated LC3 supporting accumulation of infectious progeny virus without inducing autophagosome formation. PLoS ONE. 2014;9:e95197 pubmed publisher
Hsieh M, Chen M, Yu Y, Sheu G, Chiou H. Psoralen reverses docetaxel-induced multidrug resistance in A549/D16 human lung cancer cells lines. Phytomedicine. 2014;21:970-7 pubmed publisher
Raquet N, Schrenk D. Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures. Food Chem Toxicol. 2014;68:257-66 pubmed publisher
Anokhina M, Bessonov S, Miao Z, Westhof E, Hartmuth K, Luhrmann R. RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core. EMBO J. 2013;32:2804-18 pubmed publisher
Ramamoorthy M, May A, Tadokoro T, Popuri V, Seidman M, Croteau D, et al. The RecQ helicase RECQL5 participates in psoralen-induced interstrand cross-link repair. Carcinogenesis. 2013;34:2218-30 pubmed publisher
Reyes A, Kazak L, Wood S, Yasukawa T, Jacobs H, Holt I. Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts. Nucleic Acids Res. 2013;41:5837-50 pubmed publisher
Suhasini A, Sommers J, Muniandy P, Coulombe Y, Cantor S, Masson J, et al. Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response. Mol Cell Biol. 2013;33:2212-27 pubmed publisher
McNeill D, Paramasivam M, Baldwin J, Huang J, Vyjayanti V, Seidman M, et al. NEIL1 responds and binds to psoralen-induced DNA interstrand crosslinks. J Biol Chem. 2013;288:12426-36 pubmed publisher
Kouzine F, Gupta A, Baranello L, Wójtowicz D, Ben Aissa K, Liu J, et al. Transcription-dependent dynamic supercoiling is a short-range genomic force. Nat Struct Mol Biol. 2013;20:396-403 pubmed publisher
Furuhashi T, Saito C, Torii K, Nishida E, Yamazaki S, Morita A. Photo(chemo)therapy reduces circulating Th17 cells and restores circulating regulatory T cells in psoriasis. PLoS ONE. 2013;8:e54895 pubmed publisher
Khafagy N, Salem S, Ghaly E. Comparative study of systemic psoralen and ultraviolet A and narrowband ultraviolet B in treatment of chronic urticaria. Photodermatol Photoimmunol Photomed. 2013;29:12-7 pubmed publisher
Smith L, Makarova A, Samson L, Thiesen K, Dhar A, Bessho T. Bypass of a psoralen DNA interstrand cross-link by DNA polymerases β, ι, and κ in vitro. Biochemistry. 2012;51:8931-8 pubmed publisher
Vare D, Groth P, Carlsson R, Johansson F, Erixon K, Jenssen D. DNA interstrand crosslinks induce a potent replication block followed by formation and repair of double strand breaks in intact mammalian cells. DNA Repair (Amst). 2012;11:976-85 pubmed publisher
Chen W, Li J, Qu H, Song Z, Yang Z, Huo J, et al. The melanocortin 1 receptor (MC1R) inhibits the inflammatory response in Raw 264.7 cells and atopic dermatitis (AD) mouse model. Mol Biol Rep. 2013;40:1987-96 pubmed publisher
Macias V, Marques Pinto G, Cardoso J. Phototherapy for pityriasis lichenoides: our experience. Cutan Ocul Toxicol. 2013;32:124-7 pubmed publisher
Diwan R, Malpathak N. Effect of polyamines on shoot multiplication and furanocoumarin production in Ruta graveolens cultures. Nat Prod Commun. 2012;7:895-8 pubmed
Yang Z, Huang J, Liu S, Zhao Y, Shen Z, Wang Y, et al. The osteoprotective effect of psoralen in ovariectomy-induced osteoporotic rats via stimulating the osteoblastic differentiation from bone mesenchymal stem cells. Menopause. 2012;19:1156-64 pubmed
Fan H, Liao K, Hu W, Su J, Tian Y, Qi F, et al. [Kinetic study on pyrolysis of psoralen]. Zhongguo Zhong Yao Za Zhi. 2012;37:207-11 pubmed
Meitei K, Ali S. Fig leaf extract and its bioactive compound psoralen induces skin darkening effect in reptilian melanophores via cholinergic receptor stimulation. In Vitro Cell Dev Biol Anim. 2012;48:335-9 pubmed publisher
Yamada M, Okumoto A, Yamada T. Preparation of DNA-polyintercalator conjugate and its functional property. Int J Biol Macromol. 2012;51:215-20 pubmed publisher
Robinson A, Van Voorhees A, Hsu S, Korman N, Lebwohl M, Bebo B, et al. Treatment of pustular psoriasis: from the Medical Board of the National Psoriasis Foundation. J Am Acad Dermatol. 2012;67:279-88 pubmed publisher
Dubensky T, SKOBLE J, Lauer P, Brockstedt D. Killed but metabolically active vaccines. Curr Opin Biotechnol. 2012;23:917-23 pubmed publisher
Kluger N, Jacot W, Frouin E, Rigau V, Poujol S, Dereure O, et al. Permanent scalp alopecia related to breast cancer chemotherapy by sequential fluorouracil/epirubicin/cyclophosphamide (FEC) and docetaxel: a prospective study of 20 patients. Ann Oncol. 2012;23:2879-2884 pubmed publisher
Baigude H, Ahsanullah -, Li Z, Zhou Y, Rana T. miR-TRAP: a benchtop chemical biology strategy to identify microRNA targets. Angew Chem Int Ed Engl. 2012;51:5880-3 pubmed publisher
Ozkan I, Kose O, Ozmen I, Arca E. Efficacy and safety of non-laser, targeted UVB phototherapy alone and in combination with psoralen gel or calcipotriol ointment in the treatment of localized, chronic, plaque-type psoriasis. Int J Dermatol. 2012;51:609-13 pubmed publisher
Leanza L, Henry B, Sassi N, Zoratti M, Chandy K, Gulbins E, et al. Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells. EMBO Mol Med. 2012;4:577-93 pubmed publisher
Walker D, Martínez Fernández D, Correal E, Romero Espinar P, Antonio Del Río J. Accumulation of furanocoumarins by Bituminaria bituminosa in relation to plant development and environmental stress. Plant Physiol Biochem. 2012;54:133-9 pubmed publisher
Nagase K, Hirashima N, Koba S, Inoue T, Misago N, Narisawa Y. Acquired dermal melanocytosis induced by psoralen plus ultraviolet A therapy. Acta Derm Venereol. 2012;92:691-2 pubmed publisher
Qiu R, Li L, Zhu M, Liu J. [Study on the chemical constituents of Psoralea corylifolia]. Zhong Yao Cai. 2011;34:1211-3 pubmed
Marumoto S, Miyazawa M. Structure-activity relationships for naturally occurring coumarins as ?-secretase inhibitor. Bioorg Med Chem. 2012;20:784-8 pubmed publisher
Xu R, Cao M, Wu X, Wang X, Ruan L, Quan X, et al. Kv1.3 channels as a potential target for immunomodulation of CD4+ CD28null T cells in patients with acute coronary syndrome. Clin Immunol. 2012;142:209-17 pubmed publisher
Borgatti M, Chilin A, Piccagli L, Lampronti I, Bianchi N, Mancini I, et al. Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects. Eur J Med Chem. 2011;46:4870-7 pubmed publisher
Poortinga G, Wall M, Sanij E, Siwicki K, Ellul J, Brown D, et al. c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiation. Nucleic Acids Res. 2011;39:3267-81 pubmed publisher
Piccagli L, Borgatti M, Nicolis E, Bianchi N, Mancini I, Lampronti I, et al. Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis. Bioorg Med Chem. 2010;18:8341-9 pubmed publisher
Zhang B, Fan C, Dong L, Wang F, Yue J. Structural modification of a specific antimicrobial lead against Helicobacter pylori discovered from traditional Chinese medicine and a structure-activity relationship study. Eur J Med Chem. 2010;45:5258-64 pubmed publisher
Davis R, Demirkiran O, Sykes M, Avery V, Suraweera L, Fechner G, et al. 7',8'-Dihydroobolactone, a typanocidal alpha-pyrone from the rainforest tree Cryptocarya obovata. Bioorg Med Chem Lett. 2010;20:4057-9 pubmed publisher
Diwan R, Malpathak N. Furanocoumarins: novel topoisomerase I inhibitors from Ruta graveolens L. Bioorg Med Chem. 2009;17:7052-5 pubmed publisher
Perez Montoto L, Santana L, González Díaz H. Scoring function for DNA-drug docking of anticancer and antiparasitic compounds based on spectral moments of 2D lattice graphs for molecular dynamics trajectories. Eur J Med Chem. 2009;44:4461-9 pubmed publisher
Martin S, Shisler J. Early viral protein synthesis is necessary for NF-kappaB activation in modified vaccinia Ankara (MVA)-infected 293 T fibroblast cells. Virology. 2009;390:298-306 pubmed publisher
Stern R. Psoralen and ultraviolet a light therapy for psoriasis. N Engl J Med. 2007;357:682-90 pubmed
Diffey B. The contribution of medical physics to the development of psoralen photochemotherapy (PUVA) in the UK: a personal reminiscence. Phys Med Biol. 2006;51:R229-44 pubmed
Fontana E, Dansette P, Poli S. Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr Drug Metab. 2005;6:413-54 pubmed
Barraja P, Sciabica L, Diana P, Lauria A, Montalbano A, Almerico A, et al. Synthesis and photochemotherapeutic activity of thiopyrano[2,3-e]indol-2-ones. Bioorg Med Chem Lett. 2005;15:2291-4 pubmed
Kinsler V, Hawk J, Atherton D. Diffuse cutaneous mastocytosis treated with psoralen photochemotherapy: case report and review of the literature. Br J Dermatol. 2005;152:179-80 pubmed
Morison W. Psoralen ultraviolet A therapy in 2004. Photodermatol Photoimmunol Photomed. 2004;20:315-20 pubmed
McKenna K. Iatrogenic skin cancer: induction by psoralen/ultraviolet A and immunosuppression of organ transplant recipients. Photodermatol Photoimmunol Photomed. 2004;20:289-96 pubmed
McGinnis K, Shapiro M, Vittorio C, Rook A, Junkins Hopkins J. Psoralen plus long-wave UV-A (PUVA) and bexarotene therapy: An effective and synergistic combined adjunct to therapy for patients with advanced cutaneous T-cell lymphoma. Arch Dermatol. 2003;139:771-5 pubmed
Ma W, Wlaschek M, Hommel C, Schneider L, Scharffetter Kochanek K. Psoralen plus UVA (PUVA) induced premature senescence as a model for stress-induced premature senescence. Exp Gerontol. 2002;37:1197-201 pubmed
Wollowitz S. Fundamentals of the psoralen-based Helinx technology for inactivation of infectious pathogens and leukocytes in platelets and plasma. Semin Hematol. 2001;38:4-11 pubmed
Wellinger R, Lucchini R, Dammann R, Sogo J. In vivo mapping of nucleosomes using psoralen-DNA crosslinking and primer extension. Methods Mol Biol. 1999;119:161-73 pubmed
Gasparro F, Liao B, Foley P, Wang X, McNiff J. Psoralen photochemotherapy, clinical efficacy, and photomutagenicity: the role of molecular epidemiology in minimizing risks. Environ Mol Mutagen. 1998;31:105-12 pubmed
Cullinane C, Bohr V. DNA interstrand cross-links induced by psoralen are not repaired in mammalian mitochondria. Cancer Res. 1998;58:1400-4 pubmed
McClelland P, Morgan P, Leach E, Shelk J. Psoralen photochemotherapy. Dermatol Nurs. 1997;9:403-15; quiz 416-7 pubmed
Moor A, Gasparro F. Biochemical aspects of psoralen photochemotherapy. Clin Dermatol. 1996;14:353-65 pubmed
Kornhauser A, Wamer W, Giles A. Psoralen phototoxicity: correlation with serum and epidermal 8-methoxypsoralen and 5-methoxypsoralen in the guinea pig. Science. 1982;217:733-5 pubmed
Pathak M. Molecular aspects of drug photosensitivity with special emphasis on psoralen photosensitization reaction. J Natl Cancer Inst. 1982;69:163-70 pubmed
product information
Catalog Number :
P8399
Product Name :
Psoralen
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥99% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA