Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; 1:2000; loading ...; fig 2
| Lopes Rodrigues V, Di Luca A, Mleczko J, Meleady P, Henry M, Pesic M, et al. Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles. Sci Rep. 2017;7:44541 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 3a
| Seebacher N, Richardson D, Jansson P. A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC. Cell Death Dis. 2016;7:e2510 pubmed publisher
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- immunohistochemistry; human
- western blot; human
| Jansson P, Yamagishi T, Arvind A, Seebacher N, Gutierrez E, Stacy A, et al. Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes multidrug resistance by a novel mechanism involving the hijacking of lysosomal P-glycoprotein (Pgp). J Biol Chem. 2015;290:9588-603 pubmed publisher
|
| Katt M, Mayo L, Ellis S, Mahairaki V, Rothstein J, Cheng L, et al. The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model. Fluids Barriers CNS. 2019;16:20 pubmed publisher
|
| Ji N, Yang Y, Cai C, Wang J, Lei Z, Wu Z, et al. Midostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study. Front Oncol. 2019;9:514 pubmed publisher
|
| De Vera A, Gupta P, Lei Z, Liao D, Narayanan S, Teng Q, et al. Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo. Cancer Lett. 2019;442:91-103 pubmed publisher
|
| Ji N, Yang Y, Cai C, Lei Z, Wang J, Gupta P, et al. VS-4718 Antagonizes Multidrug Resistance in ABCB1- and ABCG2-Overexpressing Cancer Cells by Inhibiting the Efflux Function of ABC Transporters. Front Pharmacol. 2018;9:1236 pubmed publisher
|
| Wang H, Gao Z, Liu X, Agarwal P, Zhao S, Conroy D, et al. Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance. Nat Commun. 2018;9:562 pubmed publisher
|
| Al Akra L, Bae D, Sahni S, Huang M, Park K, Lane D, et al. Tumor stressors induce two mechanisms of intracellular P-glycoprotein-mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones. J Biol Chem. 2018;293:3562-3587 pubmed publisher
|
| Inci F, Celik U, Turken B, Özer H, Kok F. Construction of P-glycoprotein incorporated tethered lipid bilayer membranes. Biochem Biophys Rep. 2015;2:115-122 pubmed publisher
|
| Wang C, Huang C, Chou P, Chang Y, Wei S, Guengerich F, et al. 7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway. Oncotarget. 2017;8:66033-66050 pubmed publisher
|
| Lopes Rodrigues V, Oliveira A, Correia da Silva M, Pinto M, Lima R, Sousa E, et al. A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. Bioorg Med Chem. 2017;25:581-596 pubmed publisher
|
| Ma J, Zhang Y, Tang K, Zhang H, Yin X, Li Y, et al. Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles. Cell Res. 2016;26:713-27 pubmed publisher
|
| Zhang Y, Zhang G, Wang Y, Patel B, Talele T, Yang D, et al. Bafetinib (INNO-406) reverses multidrug resistance by inhibiting the efflux function of ABCB1 and ABCG2 transporters. Sci Rep. 2016;6:25694 pubmed publisher
|
| Wang Y, Huang Y, Anreddy N, Zhang G, Zhang Y, Xie M, et al. Tea nanoparticle, a safe and biocompatible nanocarrier, greatly potentiates the anticancer activity of doxorubicin. Oncotarget. 2016;7:5877-91 pubmed publisher
|
| Seebacher N, Lane D, Jansson P, Richardson D. Glucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug Transporter. J Biol Chem. 2016;291:3796-820 pubmed publisher
|
| Giuliano S, Cormerais Y, Dufies M, Grepin R, Colosetti P, Belaid A, et al. Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux. Autophagy. 2015;11:1891-904 pubmed publisher
|
| Zhang Y, Zhang H, Zhang G, Wang Y, Kathawala R, Si R, et al. Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents. Oncotarget. 2015;6:24277-90 pubmed
|
| Ween M, Armstrong M, Oehler M, Ricciardelli C. The role of ABC transporters in ovarian cancer progression and chemoresistance. Crit Rev Oncol Hematol. 2015;96:220-56 pubmed publisher
|
| Seebacher N, Richardson D, Jansson P. Glucose modulation induces reactive oxygen species and increases P-glycoprotein-mediated multidrug resistance to chemotherapeutics. Br J Pharmacol. 2015;172:2557-72 pubmed publisher
|
| Kadova Z, Dolezelova E, Cermanova J, Hroch M, Laho T, Muchova L, et al. IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats. Am J Physiol Renal Physiol. 2015;308:F388-99 pubmed publisher
|
| Wang Y, Kathawala R, Zhang Y, Patel A, Kumar P, Shukla S, et al. Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1. Biochem Pharmacol. 2014;90:367-78 pubmed publisher
|
| Dessilly G, Elens L, Panin N, Capron A, Decottignies A, Demoulin J, et al. ABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell lines. PLoS ONE. 2014;9:e91555 pubmed publisher
|
| Ma Q, Zhang Y, Shi J, Li G. Clinical significance of P-glycoprotein and glutathione S-transferase ? expression in gallbladder carcinoma. Exp Ther Med. 2014;7:635-639 pubmed
|
| Yamagishi T, Sahni S, Sharp D, Arvind A, Jansson P, Richardson D. P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration. J Biol Chem. 2013;288:31761-71 pubmed publisher
|
| Yosef N, Ubogu E. An immortalized human blood-nerve barrier endothelial cell line for in vitro permeability studies. Cell Mol Neurobiol. 2013;33:175-86 pubmed publisher
|
| Su C. Tanshinone IIA potentiates the efficacy of 5-FU in Colo205 colon cancer cells in vivo through downregulation of P-gp and LC3-II. Exp Ther Med. 2012;3:555-559 pubmed
|
| Ferreira P, Ruela de Sousa R, Queiroz K, Souza A, Milani R, Pilli R, et al. Knocking down low molecular weight protein tyrosine phosphatase (LMW-PTP) reverts chemoresistance through inactivation of Src and Bcr-Abl proteins. PLoS ONE. 2012;7:e44312 pubmed publisher
|
| Mason C, Buhimschi I, Buhimschi C, Dong Y, Weiner C, Swaan P. ATP-binding cassette transporter expression in human placenta as a function of pregnancy condition. Drug Metab Dispos. 2011;39:1000-7 pubmed publisher
|
| Abraham I, Jain S, Wu C, Khanfar M, Kuang Y, Dai C, et al. Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells. Biochem Pharmacol. 2010;80:1497-506 pubmed publisher
|
| Shen T, Kuang Y, Ashby C, Lei Y, Chen A, Zhou Y, et al. Imatinib and nilotinib reverse multidrug resistance in cancer cells by inhibiting the efflux activity of the MRP7 (ABCC10). PLoS ONE. 2009;4:e7520 pubmed publisher
|
| Kuang Y, Shen T, Chen X, Sodani K, Hopper Borge E, Tiwari A, et al. Lapatinib and erlotinib are potent reversal agents for MRP7 (ABCC10)-mediated multidrug resistance. Biochem Pharmacol. 2010;79:154-61 pubmed publisher
|
| Zhou Y, Hopper Borge E, Shen T, Huang X, Shi Z, Kuang Y, et al. Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance. Biochem Pharmacol. 2009;77:993-1001 pubmed publisher
|
| Shi Z, Tiwari A, Shukla S, Robey R, Kim I, Parmar S, et al. Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478. Biochem Pharmacol. 2009;77:781-93 pubmed publisher
|
| Lemaire S, Van Bambeke F, Mingeot Leclercq M, Tulkens P. Modulation of the cellular accumulation and intracellular activity of daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) efflux transporter in human THP-1 macrophages and madin-darby canine kidney cells. Antimicrob Agents Chemother. 2007;51:2748-57 pubmed
|
| Azzariti A, Colabufo N, Berardi F, Porcelli L, Niso M, Simone G, et al. Cyclohexylpiperazine derivative PB28, a sigma2 agonist and sigma1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer. Mol Cancer Ther. 2006;5:1807-16 pubmed
|
| Leitch G, Scanlon M, Shaw A, Visvesvara G. Role of P glycoprotein in the course and treatment of Encephalitozoon microsporidiosis. Antimicrob Agents Chemother. 2001;45:73-8 pubmed
|
| Chu T, Lin T, Kawinski E. Detection of soluble P-glycoprotein in culture media and extracellular fluids. Biochem Biophys Res Commun. 1994;203:506-12 pubmed
|
| Chu T, Kawinski E, Lin T. Characterization of a new monoclonal antibody F4 detecting cell surface epitope and P-glycoprotein in drug-resistant human tumor cell lines. Hybridoma. 1993;12:417-29 pubmed
|