Schmitt A, Garcia J, Hung T, Flynn R, Shen Y, Qu K, et al. An inducible long noncoding RNA amplifies DNA damage signaling. Nat Genet. 2016;48:1370-1376 pubmed publisher

Shang R, Zhang F, Xu B, Xi H, Zhang X, Wang W, et al. Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects. Nat Commun. 2015;6:8430 pubmed publisher

Kirschner K, Samarajiwa S, Cairns J, Menon S, Perez Mancera P, Tomimatsu K, et al. Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. PLoS Genet. 2015;11:e1005053 pubmed publisher

McDonnell S, Spiller D, White M, Prior I, Paraoan L. ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions. Cell Death Discov. 2019;5:132 pubmed publisher

Steels A, Vannevel L, Zwaenepoel O, Gettemans J. Nb-induced stabilisation of p53 in HPV-infected cells. Sci Rep. 2019;9:12680 pubmed publisher

Miao H, Wang L, Zhan H, Dai J, Chang Y, Wu F, et al. A long noncoding RNA distributed in both nucleus and cytoplasm operates in the PYCARD-regulated apoptosis by coordinating the epigenetic and translational regulation. PLoS Genet. 2019;15:e1008144 pubmed publisher

Chen H, Huang H, Zhao J, Wang Z, Chang M, Xue L, et al. Age-dependent copy number variations of TP53 tumour suppressor gene associated with altered phosphorylation status of p53 protein in sporadic schwannomas. J Neurooncol. 2019;143:369-379 pubmed publisher

Chen H, Xue L, Huang H, Wang H, Zhang X, Zhu W, et al. Synergistic effect of Nutlin-3 combined with MG-132 on schwannoma cells through restoration of merlin and p53 tumour suppressors. EBioMedicine. 2018;36:252-265 pubmed publisher

Yusenko M, Jakobs A, Klempnauer K. A novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity. Sci Rep. 2018;8:13159 pubmed publisher

Wiesmann N, Strozynski J, Beck C, Zimmermann N, Mendler S, Gieringer R, et al. Knockdown of hnRNPK leads to increased DNA damage after irradiation and reduces survival of tumor cells. Carcinogenesis. 2017;38:321-328 pubmed publisher

Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D Angelo C, et al. SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage. Nucleic Acids Res. 2017;45:1820-1834 pubmed publisher

Pfister N, Fomin V, Regunath K, Zhou J, Zhou W, Silwal Pandit L, et al. Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells. Genes Dev. 2015;29:1298-315 pubmed publisher

Minamino M, Oka T, Kanouchi H. Growth suppression and cell death by pyridoxal is dependent on p53 in the human breast cancer cell line MCF-7. Biosci Biotechnol Biochem. 2015;79:124-9 pubmed publisher

Cook G, Caudell D, Elford H, Pardee T. The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML. PLoS ONE. 2014;9:e112619 pubmed publisher

Xie D, Lan L, Huang K, Chen L, Xu C, Wang R, et al. Association of p53/p21 expression and cigarette smoking with tumor progression and poor prognosis in non-small cell lung cancer patients. Oncol Rep. 2014;32:2517-26 pubmed publisher

Yu H, Yue X, Zhao Y, Li X, Wu L, Zhang C, et al. LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers. Nat Commun. 2014;5:5218 pubmed publisher

Mohamed M, Mohamed M, Fathi M, Shouman S, Abdelhamid I. Chalcones incorporated pyrazole ring inhibit proliferation, cell cycle progression, angiogenesis and induce apoptosis of MCF7 cell line. Anticancer Agents Med Chem. 2014;14:1282-92 pubmed

Sun Y, Chen C, Zhang P, Xie H, Hou L, Hui Z, et al. Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway. Sci Rep. 2014;4:6527 pubmed publisher

Ivanov V, Hei T. Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC). Apoptosis. 2014;19:1736-54 pubmed publisher

Jiao F, Hu H, Yuan C, Wang L, Jiang W, Jin Z, et al. Elevated expression level of long noncoding RNA MALAT-1 facilitates cell growth, migration and invasion in pancreatic cancer. Oncol Rep. 2014;32:2485-92 pubmed publisher

Vizioli M, Santos J, Pilotti S, Mazzoni M, Anania M, Miranda C, et al. Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved. Oncotarget. 2014;5:8270-83 pubmed

Williams R, Hubberstey A. Benzo(a)pyrene exposure causes adaptive changes in p53 and CYP1A gene expression in Brown bullhead (Ameiurus nebulosus). Aquat Toxicol. 2014;156:201-10 pubmed publisher

van der Ent W, Burrello C, Teunisse A, Ksander B, van der Velden P, Jager M, et al. Modeling of human uveal melanoma in zebrafish xenograft embryos. Invest Ophthalmol Vis Sci. 2014;55:6612-22 pubmed publisher

Ma Y, Gong Y, Cheng Z, Loganathan S, Kao C, Sarkaria J, et al. Critical functions of RhoB in support of glioblastoma tumorigenesis. Neuro Oncol. 2015;17:516-25 pubmed publisher

Murao K, Yoshioka R, Kubo Y. Human papillomavirus infection in Bowen disease: negative p53 expression, not p16(INK4a) overexpression, is correlated with human papillomavirus-associated Bowen disease. J Dermatol. 2014;41:878-84 pubmed publisher

Chen H, Guo S, Li Z, Lu Y, Jiang D, Zhang R, et al. A critical role for interferon regulatory factor 9 in cerebral ischemic stroke. J Neurosci. 2014;34:11897-912 pubmed publisher

Forini F, Kusmic C, Nicolini G, Mariani L, Zucchi R, Matteucci M, et al. Triiodothyronine prevents cardiac ischemia/reperfusion mitochondrial impairment and cell loss by regulating miR30a/p53 axis. Endocrinology. 2014;155:4581-90 pubmed publisher

Raoof M, Zhu C, Cisneros B, Liu H, Corr S, Wilson L, et al. Hyperthermia inhibits recombination repair of gemcitabine-stalled replication forks. J Natl Cancer Inst. 2014;106: pubmed publisher

Tomicic M, Aasland D, Naumann S, Meise R, Barckhausen C, Kaina B, et al. Translesion polymerase ? is upregulated by cancer therapeutics and confers anticancer drug resistance. Cancer Res. 2014;74:5585-96 pubmed publisher

Xin Y, Zhang H, Tang T, Liu G, Wang J, Jiang G, et al. Low‑dose radiation‑induced apoptosis in human leukemia K562 cells through mitochondrial pathways. Mol Med Rep. 2014;10:1569-75 pubmed publisher

Okadome M, Saito T, Nishiyama N, Ariyoshi K, Shimamoto K, Shimada T, et al. Prediction of histological types of endometrial cancer by endometrial cytology. J Obstet Gynaecol Res. 2014;40:1931-9 pubmed publisher

Yamaguchi T, Ikehara S, Nakanishi H, Ikehara Y. A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma. J Pathol. 2014;234:228-38 pubmed publisher

Su L, Zheng H, Li Z, Qiu J, Chen S, Liu J, et al. Mechanistic studies on the anticancer activity of 2,4-disubstituted quinazoline derivative. Biochim Biophys Acta. 2014;1840:3123-30 pubmed publisher

van der Ent W, Jochemsen A, Teunisse A, Krens S, Szuhai K, Spaink H, et al. Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53. J Pathol. 2014;233:415-24 pubmed publisher

Pardee T, Stadelman K, Jennings Gee J, Caudell D, Gmeiner W. The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells. Oncotarget. 2014;5:4170-9 pubmed

Mylona E, Melissaris S, Nomikos A, Theohari I, Giannopoulou I, Tzelepis K, et al. Effect of BRCA1 immunohistochemical localizations on prognosis of patients with sporadic breast carcinomas. Pathol Res Pract. 2014;210:533-40 pubmed publisher

Yeh C, Yen C, Chen Y, Cheng C, Huang S, Chang T, et al. Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumors. Oncotarget. 2014;5:4071-86 pubmed

Shoji K, Teishima J, Hayashi T, Ohara S, McKeehan W, Matsubara A. Restoration of fibroblast growth factor receptor 2IIIb enhances the chemosensitivity of human prostate cancer cells. Oncol Rep. 2014;32:65-70 pubmed publisher

van Miltenburg M, van Nimwegen M, Tijdens I, Lalai R, Kuiper R, Klarenbeek S, et al. Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation. Br J Cancer. 2014;110:2747-55 pubmed publisher

Iqbal N, Xu L, Devitt C, Skapek S. Isolation and characterization of mammalian cells expressing the Arf promoter during eye development. Biotechniques. 2014;56:239-49 pubmed publisher

Kitamura Y, Ito M, Matsuo T, Boda T, Oka S, Yoshihara M, et al. Characteristic epithelium with low-grade atypia appears on the surface of gastric cancer after successful Helicobacter pylori eradication therapy. Helicobacter. 2014;19:289-95 pubmed publisher

Guo X, Sesaki H, Qi X. Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo. Biochem J. 2014;461:137-46 pubmed publisher

Bohanon F, Wang X, Ding C, Ding Y, Radhakrishnan G, Rastellini C, et al. Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis. J Surg Res. 2014;190:55-63 pubmed publisher

Ke R, Wang Y, Mao Y, Zhang J, Xiong J. Decreased expression of LASS2 is associated with worse prognosis in meningiomas. J Neurooncol. 2014;118:369-376 pubmed publisher

Yu Z, Xu Z, Disante G, Wright J, Wang M, Li Y, et al. miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. Oncotarget. 2014;5:1083-90 pubmed

Sin T, Yu A, Yung B, Yip S, Chan L, Wong C, et al. Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart. J Physiol. 2014;592:2535-48 pubmed publisher

Li Q, Zhang Y, El Naggar A, Xiong S, Yang P, Jackson J, et al. Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors. Mol Cancer Res. 2014;12:901-11 pubmed publisher

Laget S, Miotto B, Chin H, Esteve P, Roberts R, Pradhan S, et al. MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress. Epigenetics. 2014;9:546-56 pubmed publisher

Barbieri E, De Preter K, Capasso M, Chen Z, Hsu D, Tonini G, et al. Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma. Cancer Res. 2014;74:765-74 pubmed publisher

Karabulut S, Demiroglu Zergeroglu A, Yilmaz E, Sagir F, Delikara N. p53 and mitogen-activated protein kinase pathway protein profiles in fresh and frozen spermatozoa. Andrologia. 2014;46:1113-7 pubmed publisher

Park H, Park J, Park S, Cho J, Kim S, Park B. Subcellular localization of Mdm2 expression and prognosis of breast cancer. Int J Clin Oncol. 2014;19:842-51 pubmed publisher

Benbrook D, Nammalwar B, Long A, Matsumoto H, Singh A, Bunce R, et al. SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheres. Invest New Drugs. 2014;32:412-23 pubmed publisher

Leufke C, Leykauf J, Krunic D, Jauch A, Holtgreve Grez H, Böhm Steuer B, et al. The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas. Oncogene. 2014;33:3506-18 pubmed publisher

Sangar F, Schreurs A, Umana Diaz C, Claperon A, Desbois Mouthon C, Calmel C, et al. Involvement of small ArfGAP1 (SMAP1), a novel Arf6-specific GTPase-activating protein, in microsatellite instability oncogenesis. Oncogene. 2014;33:2758-67 pubmed publisher

You B, Park W. Zebularine inhibits the growth of A549 lung cancer cells via cell cycle arrest and apoptosis. Mol Carcinog. 2014;53:847-57 pubmed publisher

Wedeken L, Singh P, Klempnauer K. Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA. J Biol Chem. 2011;286:42855-62 pubmed publisher

Ng K, Ebrahem Q, Negrotto S, Mahfouz R, Link K, Hu Z, et al. p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia. Leukemia. 2011;25:1739-50 pubmed publisher

Vilas Zornoza A, Agirre X, Martín Palanco V, Martin Subero J, San Jose Eneriz E, Garate L, et al. Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia. PLoS ONE. 2011;6:e17012 pubmed publisher

Negrotto S, Hu Z, Alcazar O, Ng K, Triozzi P, Lindner D, et al. Noncytotoxic differentiation treatment of renal cell cancer. Cancer Res. 2011;71:1431-41 pubmed publisher

Yu W, Qiu Z, Gao N, Wang L, Cui H, Qian Y, et al. PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53-MDM2 loop. Nucleic Acids Res. 2011;39:2234-48 pubmed publisher

Lindström M, Nister M. Silencing of ribosomal protein S9 elicits a multitude of cellular responses inhibiting the growth of cancer cells subsequent to p53 activation. PLoS ONE. 2010;5:e9578 pubmed publisher

Hubbard K, Catalano J, Puri R, Gnatt A. Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis. BMC Cancer. 2008;8:133 pubmed publisher

Soria G, Podhajcer O, Prives C, Gottifredi V. P21Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation. Oncogene. 2006;25:2829-38 pubmed

Schneider E, Montenarh M, Wagner P. Regulation of CAK kinase activity by p53. Oncogene. 1998;17:2733-41 pubmed

Bonsing B, Corver W, Gorsira M, van Vliet M, Oud P, Cornelisse C, et al. Specificity of seven monoclonal antibodies against p53 evaluated with Western blotting, immunohistochemistry, confocal laser scanning microscopy, and flow cytometry. Cytometry. 1997;28:11-24 pubmed