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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Pilocarpine nitrate salt
catalog :
P6628
citations: 56
Reference
Cai F, Gao L, Gong H, Jiang F, Pei C, Zhang X, et al. Network Centrality of Resting-State fMRI in Primary Angle-Closure Glaucoma Before and After Surgery. PLoS ONE. 2015;10:e0141389 pubmed publisher
Römermann K, Bankstahl J, Löscher W, Bankstahl M. Pilocarpine-induced convulsive activity is limited by multidrug transporters at the rodent blood-brain barrier. J Pharmacol Exp Ther. 2015;353:351-9 pubmed publisher
Asuntha G, Raju Y, Sundaresan C, Rasheed A, Chowdary V, Vandana K, et al. Effect of Argemone mexicana (L.) against lithium-pilocarpine induced status epilepticus and oxidative stress in Wistar rats. Indian J Exp Biol. 2015;53:31-5 pubmed
Zhang Y, Shen W, Zhang L, Pan Z, Long C, Cui W, et al. Proteomics reveals potential non-neuronal cholinergic receptor-effectors in endothelial cells. Acta Pharmacol Sin. 2014;35:1137-49 pubmed publisher
Pothmann L, Müller C, Averkin R, Bellistri E, Miklitz C, Uebachs M, et al. Function of inhibitory micronetworks is spared by Na+ channel-acting anticonvulsant drugs. J Neurosci. 2014;34:9720-35 pubmed publisher
He L, Wendt M, Glasser A. Pharmacologically and Edinger-Westphal stimulated accommodation in rhesus monkeys does not rely on changes in anterior chamber pressure. Exp Eye Res. 2014;125:244-55 pubmed publisher
Shrot S, Ramaty E, Biala Y, Bar Klein G, Daninos M, Kamintsky L, et al. Prevention of organophosphate-induced chronic epilepsy by early benzodiazepine treatment. Toxicology. 2014;323:19-25 pubmed publisher
Soukupova M, Binaschi A, Falcicchia C, Zucchini S, Roncon P, Palma E, et al. Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy. Exp Neurol. 2014;257:39-49 pubmed publisher
Pimentel M, Filho M, Araújo M, Gomes D, da Costa L. Evaluation of radioprotective effect of pilocarpine ingestion on salivary glands. Anticancer Res. 2014;34:1993-9 pubmed
Aqil B, West A, Dowlin M, Tam E, Nordstrom C, Buffone G, et al. Implementation of a quality improvement program to improve sweat test performance in a pediatric hospital. Arch Pathol Lab Med. 2014;138:920-2 pubmed publisher
Hadera M, Smeland O, McDonald T, Tan K, Sonnewald U, Borges K. Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy. J Neurochem. 2014;129:107-19 pubmed publisher
Clasadonte J, Dong J, Hines D, Haydon P. Astrocyte control of synaptic NMDA receptors contributes to the progressive development of temporal lobe epilepsy. Proc Natl Acad Sci U S A. 2013;110:17540-5 pubmed publisher
Temp F, Santos A, Marafiga J, Jesse A, Lenz Q, Oliveira S, et al. Alpha melanocyte stimulating hormone (α-MSH) does not modify pentylenetetrazol- and pilocarpine-induced seizures. Life Sci. 2013;93:723-31 pubmed publisher
Vargas J, Takahashi D, Thomson K, Wilcox K. The expression of kainate receptor subunits in hippocampal astrocytes after experimentally induced status epilepticus. J Neuropathol Exp Neurol. 2013;72:919-32 pubmed publisher
Peng Z, Zhang N, Wei W, Huang C, Cetina Y, Otis T, et al. A reorganized GABAergic circuit in a model of epilepsy: evidence from optogenetic labeling and stimulation of somatostatin interneurons. J Neurosci. 2013;33:14392-405 pubmed publisher
Marcos S, Ortiz S, Pérez Merino P, Birkenfeld J, Duran S, Jiménez Alfaro I. Three-dimensional evaluation of accommodating intraocular lens shift and alignment in vivo. Ophthalmology. 2014;121:45-55 pubmed publisher
Strupińska M, Rostafińska Suchar G, Pirianowicz Chaber E, Stables J, Jiang J, Paruszewski R. Synthesis and research of benzylamides of some isocyclic and heterocyclic acids as potential anticonvulsants. Acta Pol Pharm. 2013;70:681-6 pubmed
Besio W, Cuellar Herrera M, Luna Munguia H, Orozco Suarez S, Rocha L. Effects of transcranial focal electrical stimulation alone and associated with a sub-effective dose of diazepam on pilocarpine-induced status epilepticus and subsequent neuronal damage in rats. Epilepsy Behav. 2013;28:432-6 pubmed publisher
Wendt M, He L, Glasser A. Comparison between carbachol iontophoresis and intravenous pilocarpine stimulated accommodation in anesthetized rhesus monkeys. Exp Eye Res. 2013;115:123-30 pubmed publisher
Heng K, Haney M, Buckmaster P. High-dose rapamycin blocks mossy fiber sprouting but not seizures in a mouse model of temporal lobe epilepsy. Epilepsia. 2013;54:1535-41 pubmed publisher
Suidan G, Brill A, De Meyer S, Voorhees J, Cifuni S, Cabral J, et al. Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice. Arterioscler Thromb Vasc Biol. 2013;33:2112-20 pubmed publisher
Khurana S, Jadeja R, Twaddell W, Cheng K, Rachakonda V, Saxena N, et al. Effects of modulating M3 muscarinic receptor activity on azoxymethane-induced liver injury in mice. Biochem Pharmacol. 2013;86:329-38 pubmed publisher
Grasse D, Karunakaran S, Moxon K. Neuronal synchrony and the transition to spontaneous seizures. Exp Neurol. 2013;248:72-84 pubmed publisher
Hester M, Danzer S. Accumulation of abnormal adult-generated hippocampal granule cells predicts seizure frequency and severity. J Neurosci. 2013;33:8926-36 pubmed publisher
Mazzuferi M, Kumar G, van Eyll J, Danis B, Foerch P, Kaminski R. Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy. Ann Neurol. 2013;74:560-8 pubmed publisher
Pulido Rios M, McNamara A, Obedencio G, Ji Y, Jaw Tsai S, Martin W, et al. In vivo pharmacological characterization of TD-4208, a novel lung-selective inhaled muscarinic antagonist with sustained bronchoprotective effect in experimental animal models. J Pharmacol Exp Ther. 2013;346:241-50 pubmed publisher
Faure J, Akimana G, Carneiro J, Cosquer B, Ferrandon A, Geiger K, et al. A comprehensive behavioral evaluation in the lithium-pilocarpine model in rats: effects of carisbamate administration during status epilepticus. Epilepsia. 2013;54:1203-13 pubmed publisher
Khan M, Vishakante G, Bathool A. Development and characterization of pilocarpine loaded Eudragit nanosuspensions for ocular drug delivery. J Biomed Nanotechnol. 2013;9:124-31 pubmed
Smeland O, Hadera M, McDonald T, Sonnewald U, Borges K. Brain mitochondrial metabolic dysfunction and glutamate level reduction in the pilocarpine model of temporal lobe epilepsy in mice. J Cereb Blood Flow Metab. 2013;33:1090-7 pubmed publisher
abramochkin D, Tapilina S, Sukhova G. Effect of selective stimulation of muscarinic M3 cholinoceptors on electrical and contractile activity of rat ventricular myocardium. Bull Exp Biol Med. 2013;154:295-8 pubmed
Loeber D. Neuroleptic drugs. N Z Dent J. 2012;108:153 pubmed
Yang H, Guo R, Wu J, Peng Y, Xie D, Zheng W, et al. The antiepileptic effect of the glycolytic inhibitor 2-deoxy-D-glucose is mediated by upregulation of K(ATP) channel subunits Kir6.1 and Kir6.2. Neurochem Res. 2013;38:677-85 pubmed publisher
França K, de Almeida A, Infantosi A, Duarte M, da Silveira G, Scorza F, et al. Enhanced synaptic connectivity in the dentate gyrus during epileptiform activity: network simulation. Comput Intell Neurosci. 2013;2013:949816 pubmed publisher
Distler M, Gorfinkle N, Papale L, Wuenschell G, Termini J, Escayg A, et al. Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility. Epilepsia. 2013;54:649-57 pubmed publisher
Jiang J, Quan Y, Ganesh T, Pouliot W, Dudek F, Dingledine R. Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation. Proc Natl Acad Sci U S A. 2013;110:3591-6 pubmed publisher
Alvarenga T, Matos G, Scorza F, Amado D, Cavalheiro E, Tufik S, et al. Sexual response in female rats with status epilepticus. Epilepsia. 2013;54:644-8 pubmed publisher
Holtman L, van Vliet E, Aronica E, Wouters D, Wadman W, Gorter J. Blood plasma inflammation markers during epileptogenesis in post-status epilepticus rat model for temporal lobe epilepsy. Epilepsia. 2013;54:589-95 pubmed publisher
Jang M, Bonaguidi M, Kitabatake Y, Sun J, Song J, Kang E, et al. Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis. Cell Stem Cell. 2013;12:215-23 pubmed publisher
Karbowski L, Parker G, Persinger M. Post-seizure drug treatment in young rats determines clear incremental losses of frontal cortical and hippocampal neurons: the resultant damage is similar to very old brains. Epilepsy Behav. 2013;27:18-21 pubmed publisher
Yu J, Proddutur A, Elgammal F, Ito T, Santhakumar V. Status epilepticus enhances tonic GABA currents and depolarizes GABA reversal potential in dentate fast-spiking basket cells. J Neurophysiol. 2013;109:1746-63 pubmed publisher
Córdova S, Loss C, de Oliveira D. Low-intensity physical training recovers object recognition memory impairment in rats after early-life induced Status epilepticus. Int J Dev Neurosci. 2013;31:196-201 pubmed publisher
Kim J, Jang B, Choi B, Kim H, Sohn M, Chung T, et al. Post-treatment of an NADPH oxidase inhibitor prevents seizure-induced neuronal death. Brain Res. 2013;1499:163-72 pubmed publisher
da Cruz G, Felipe C, Scorza F, da Costa M, Tavares A, Menezes M, et al. Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms. Pharmacol Biochem Behav. 2013;104:144-53 pubmed publisher
Jou S, Kao I, Yi P, Chang F. Electrical stimulation of left anterior thalamic nucleus with high-frequency and low-intensity currents reduces the rate of pilocarpine-induced epilepsy in rats. Seizure. 2013;22:221-9 pubmed publisher
Risbud R, Porter B. Changes in microRNA expression in the whole hippocampus and hippocampal synaptoneurosome fraction following pilocarpine induced status epilepticus. PLoS ONE. 2013;8:e53464 pubmed publisher
Kubova H, Mares P. Are morphologic and functional consequences of status epilepticus in infant rats progressive?. Neuroscience. 2013;235:232-49 pubmed publisher
Lin W, Huang H, Lin M, Chen S, Lv X, Che C, et al. Seizure-induced 5-HT release and chronic impairment of serotonergic function in rats. Neurosci Lett. 2013;534:1-6 pubmed publisher
Seo J, Jung S, Lee S, Yang H, Kim B, Choi J, et al. Early deficits in social behavior and cortical rhythms in pilocarpine-induced mouse model of temporal lobe epilepsy. Exp Neurol. 2013;241:38-44 pubmed publisher
de Souza T, Silva I, Carvalho A, Gomes V, Duarte A, Leao J, et al. Juvenile Sjögren syndrome: distinctive age, unique findings. Pediatr Dent. 2012;34:427-30 pubmed
Li X, Yang F, Wang Y, Wang J, Ma L, Jiang W. Brain recruitment of dendritic cells following Li-pilocarpine induced status epilepticus in adult rats. Brain Res Bull. 2013;91:8-13 pubmed publisher
Phelan K, Shwe U, Abramowitz J, Wu H, Rhee S, Howell M, et al. Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms. Mol Pharmacol. 2013;83:429-38 pubmed publisher
Freddo T, Neville N, Gong H. Pilocarpine-induced flare is physiological rather than pathological. Exp Eye Res. 2013;107:37-43 pubmed publisher
Oh Y, Na J, Jeong J, Park D, Park K, Ko J, et al. Alterations in hyperpolarization-activated cyclic nucleotidegated cation channel (HCN) expression in the hippocampus following pilocarpine-induced status epilepticus. BMB Rep. 2012;45:635-40 pubmed
Andrioli A, Fabene P, Spreafico R, Cavalheiro E, Bentivoglio M. Different patterns of neuronal activation and neurodegeneration in the thalamus and cortex of epilepsy-resistant Proechimys rats versus Wistar rats after pilocarpine-induced protracted seizures. Epilepsia. 2009;50:832-48 pubmed publisher
Chang S, Bray S, Li Z, Zarnescu D, He C, Jin P, et al. Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila. Nat Chem Biol. 2008;4:256-63 pubmed publisher
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
product information
Catalog Number :
P6628
Product Name :
Pilocarpine nitrate salt
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA