Kjell J, Fischer Sternjak J, Thompson A, Friess C, Sticco M, Salinas F, et al. Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis. Cell Stem Cell. 2020;26:277-293.e8 pubmed publisher

Ma A, Stratikopoulos E, Park K, Wei J, Martin T, Yang X, et al. Discovery of a first-in-class EZH2 selective degrader. Nat Chem Biol. 2020;16:214-222 pubmed publisher

Van Ziel A, Wolzak K, Nölle A, Hoetjes P, Berenjeno Correa E, van Anken E, et al. No evidence for cell-to-cell transmission of the unfolded protein response in cell culture. J Neurochem. 2020;152:208-220 pubmed publisher

Shafa M, Walsh T, Panchalingam K, Richardson T, Menendez L, Tian X, et al. Long-Term Stability and Differentiation Potential of Cryopreserved cGMP-Compliant Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2019;21: pubmed publisher

Pandey P, Tomney A, Woon M, Uth N, Shafighi F, Ngabo I, et al. End-to-End Platform for Human Pluripotent Stem Cell Manufacturing. Int J Mol Sci. 2019;21: pubmed publisher

Stoyas C, Bushart D, Switonski P, Ward J, Alaghatta A, Tang M, et al. Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7. Neuron. 2019;: pubmed publisher

Randzavola L, Strege K, Juzans M, Asano Y, Stinchcombe J, Gawden Bone C, et al. Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019;129:5600-5614 pubmed publisher

Habib P, Stamm A, Schulz J, Reich A, Slowik A, Capellmann S, et al. EPO and TMBIM3/GRINA Promote the Activation of the Adaptive Arm and Counteract the Terminal Arm of the Unfolded Protein Response after Murine Transient Cerebral Ischemia. Int J Mol Sci. 2019;20: pubmed publisher

Persoon C, Hoogstraaten R, Nassal J, van Weering J, Kaeser P, Toonen R, et al. The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators. Neuron. 2019;104:1065-1080.e12 pubmed publisher

Zullo J, Drake D, Aron L, O Hern P, Dhamne S, Davidsohn N, et al. Regulation of lifespan by neural excitation and REST. Nature. 2019;574:359-364 pubmed publisher

Picchiarelli G, Demestre M, Zuko A, Been M, Higelin J, Dieterlé S, et al. FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis. Nat Neurosci. 2019;22:1793-1805 pubmed publisher

Kim J, Lana B, Torelli S, Ryan D, Catapano F, Ala P, et al. A new patient-derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α-dystroglycan. EMBO Rep. 2019;20:e47967 pubmed publisher

Puri R, Cheng X, Lin M, Huang N, Sheng Z. Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts. Nat Commun. 2019;10:3645 pubmed publisher

Feutz A, De Geyter C. Accuracy, discriminative properties and reliability of a human ESC-based in vitro toxicity assay to distinguish teratogens responsible for neural tube defects. Arch Toxicol. 2019;93:2375-2384 pubmed publisher

Mahmoudinia S, Niapour A, Ghasemi Hamidabadi H, Mazani M. 2,4-D causes oxidative stress induction and apoptosis in human dental pulp stem cells (hDPSCs). Environ Sci Pollut Res Int. 2019;26:26170-26183 pubmed publisher

Farfel Becker T, Roney J, Cheng X, Li S, Cuddy S, Sheng Z. Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity. Cell Rep. 2019;28:51-64.e4 pubmed publisher

Liu Z, Osipovitch M, Benraiss A, Huynh N, Foti R, Bates J, et al. Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling. Cell Rep. 2019;27:3832-3843.e6 pubmed publisher

De Santis R, Alfano V, de Turris V, Colantoni A, Santini L, Garone M, et al. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis. Cell Rep. 2019;27:3818-3831.e5 pubmed publisher

Malaguti M, Migueles R, Blin G, Lin C, Lowell S. Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation. Dev Cell. 2019;: pubmed publisher

Chantzi E, Jarvius M, Niklasson M, Segerman A, Gustafsson M. COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining. BMC Bioinformatics. 2019;20:304 pubmed publisher

Tischbein M, Baron D, Lin Y, Gall K, Landers J, Fallini C, et al. The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing. J Biol Chem. 2019;: pubmed publisher

Chung D, Salsman J, Dellaire G. Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis. Cell Cycle. 2019;18:1135-1153 pubmed publisher

Robinson M, Valente K, Willerth S. A Novel Toolkit for Characterizing the Mechanical and Electrical Properties of Engineered Neural Tissues. Biosensors (Basel). 2019;9: pubmed publisher

Vila O, Uzel S, Ma S, Williams D, Pak J, Kamm R, et al. Quantification of human neuromuscular function through optogenetics. Theranostics. 2019;9:1232-1246 pubmed publisher

Kim J, Kim J, Kim J, Jung H, Lee W, Lee J. Restorative Mechanism of Neural Progenitor Cells Overexpressing Arginine Decarboxylase Genes Following Ischemic Injury. Exp Neurobiol. 2019;28:85-103 pubmed publisher

Masnata M, Sciacca G, Maxan A, Bousset L, Denis H, Lauruol F, et al. Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms. Acta Neuropathol. 2019;137:981-1001 pubmed publisher

Ogi H, Moriwaki S, Kokubo M, Hikida Y, Itoh K. Label-free classification of neurons and glia in neural stem cell cultures using a hyperspectral imaging microscopy combined with machine learning. Sci Rep. 2019;9:633 pubmed publisher

Boija A, Klein I, Sabari B, Dall Agnese A, Coffey E, Zamudio A, et al. Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains. Cell. 2018;175:1842-1855.e16 pubmed publisher

Festuccia N, Halbritter F, Corsinotti A, Gagliardi A, Colby D, Tomlinson S, et al. Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation. EMBO J. 2018;37: pubmed publisher

Persoon C, Moro A, Nassal J, Farina M, Broeke J, Arora S, et al. Pool size estimations for dense-core vesicles in mammalian CNS neurons. EMBO J. 2018;37: pubmed publisher

Dell Anno M, Wang X, Onorati M, Li M, Talpo F, Sekine Y, et al. Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit. Nat Commun. 2018;9:3419 pubmed publisher

Milanese C, Cerri S, Ulusoy A, Gornati S, Plat A, Gabriels S, et al. Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson's disease. Cell Death Dis. 2018;9:818 pubmed publisher

Lee S, Oh Y, Lü Y, Kim W, Yoo A. MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts. Dev Cell. 2018;46:73-84.e7 pubmed publisher

Li Y, Guo B, Yang R, Xiao Z, Gao X, Yu J, et al. A novel long noncoding RNA lnc158 promotes the differentiation of mouse neural precursor cells into oligodendrocytes by targeting nuclear factor-IB. Neuroreport. 2018;29:1121-1128 pubmed publisher

Song M, Kim H, Park S, Kwon H, Joung I, Kim Kwon Y. Aucubin Promotes Differentiation of Neural Precursor Cells into GABAergic Neurons. Exp Neurobiol. 2018;27:112-119 pubmed publisher

Compeer E, Kraus F, Ecker M, Redpath G, Amiezer M, Rother N, et al. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun. 2018;9:1597 pubmed publisher

Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, et al. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. Nat Commun. 2018;9:335 pubmed publisher

Dabo S, Maillard P, Collados Rodriguez M, Hansen M, Mazouz S, Bigot D, et al. Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT. Sci Rep. 2017;7:16129 pubmed publisher

Radotić V, Braeken D, Kovacic D. Microelectrode array-induced neuronal alignment directs neurite outgrowth: analysis using a fast Fourier transform (FFT). Eur Biophys J. 2017;46:719-727 pubmed publisher

Jahn K, Wieltsch C, Blumer N, Mehlich M, Pathak H, Khan A, et al. A cell culture model for investigation of synapse influenceability: epigenetics, expression and function of gene targets important for synapse formation and preservation in SH-SY5Y neuroblastoma cells differentiated by retinoic acid. J Neural Transm (Vienna). 2017;124:1341-1367 pubmed publisher

Abernathy D, Kim W, McCoy M, Lake A, Ouwenga R, Lee S, et al. MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts. Cell Stem Cell. 2017;21:332-348.e9 pubmed publisher

Sloan S, Darmanis S, Huber N, Khan T, Birey F, Caneda C, et al. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells. Neuron. 2017;95:779-790.e6 pubmed publisher

Lin K, Moroishi T, Meng Z, Jeong H, Plouffe S, Sekido Y, et al. Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation. Nat Cell Biol. 2017;19:996-1002 pubmed publisher

Su L, Luo R, Liu Q, Su J, Yang L, Ding Y, et al. Atg5- and Atg7-dependent autophagy in dopaminergic neurons regulates cellular and behavioral responses to morphine. Autophagy. 2017;13:1496-1511 pubmed publisher

Lin M, Cheng X, Tammineni P, Xie Y, Zhou B, Cai Q, et al. Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions. Neuron. 2017;94:595-610.e6 pubmed publisher

Schampel A, Volovitch O, Koeniger T, Scholz C, Jörg S, Linker R, et al. Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis. Proc Natl Acad Sci U S A. 2017;114:E3295-E3304 pubmed publisher

Sotthibundhu A, Ekthuwapranee K, Govitrapong P. Comparison of melatonin with growth factors in promoting precursor cells proliferation in adult mouse subventricular zone. EXCLI J. 2016;15:829-841 pubmed publisher

Plouffe S, Meng Z, Lin K, Lin B, Hong A, Chun J, et al. Characterization of Hippo Pathway Components by Gene Inactivation. Mol Cell. 2016;64:993-1008 pubmed publisher

Sepulveda Diaz J, Ouidja M, Socias S, Hamadat S, Guerreiro S, Raisman Vozari R, et al. A simplified approach for efficient isolation of functional microglial cells: Application for modeling neuroinflammatory responses in vitro. Glia. 2016;64:1912-24 pubmed publisher

Amin H, Maccione A, Marinaro F, Zordan S, Nieus T, Berdondini L. Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays. Front Neurosci. 2016;10:121 pubmed publisher

Su L, Li H, Lv L, Feng Y, Li G, Luo R, et al. Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation. Autophagy. 2015;11:1745-59 pubmed publisher

Vakilian H, Mirzaei M, Sharifi Tabar M, Pooyan P, Habibi Rezaee L, Parker L, et al. DDX3Y, a Male-Specific Region of Y Chromosome Gene, May Modulate Neuronal Differentiation. J Proteome Res. 2015;14:3474-83 pubmed publisher

Riddick G, Song H, Holbeck S, Kopp W, Walling J, Ahn S, et al. An in silico screen links gene expression signatures to drug response in glioblastoma stem cells. Pharmacogenomics J. 2015;15:347-53 pubmed publisher

Brooks M, Jackson E, Warrington N, Luo J, Forys J, Taylor S, et al. PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells. PLoS ONE. 2014;9:e107397 pubmed publisher

Hillberg A, Kathirgamanathan K, Lam J, Law L, Garkavenko O, Elliott R. Improving alginate-poly-L-ornithine-alginate capsule biocompatibility through genipin crosslinking. J Biomed Mater Res B Appl Biomater. 2013;101:258-68 pubmed publisher

Khanna O, Larson J, Moya M, Opara E, Brey E. Generation of alginate microspheres for biomedical applications. J Vis Exp. 2012;: pubmed publisher

Abbah S, Liu J, Lam R, Goh J, Wong H. In vivo bioactivity of rhBMP-2 delivered with novel polyelectrolyte complexation shells assembled on an alginate microbead core template. J Control Release. 2012;162:364-72 pubmed publisher

Oda K, Yumoto R, Nagai J, Katayama H, Takano M. Enhancement effect of poly(amino acid)s on insulin uptake in alveolar epithelial cells. Drug Metab Pharmacokinet. 2012;27:570-8 pubmed

Förtsch C, Hupp S, Ma J, Mitchell T, Maier E, Benz R, et al. Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity. Toxins (Basel). 2011;3:43-62 pubmed publisher

Crews L, Ruf R, Patrick C, Dumaop W, Trejo Morales M, Achim C, et al. Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders. Mol Neurodegener. 2011;6:67 pubmed publisher

Fonte V, Dostal V, Roberts C, Gonzales P, Lacor P, Lacor P, et al. A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo. Mol Neurodegener. 2011;6:61 pubmed publisher

Dhara S, Majumder A, Dodla M, Stice S. Nonviral gene delivery in neural progenitors derived from human pluripotent stem cells. Methods Mol Biol. 2011;767:343-54 pubmed publisher

Wang Y, Pang X, Zhitomirsky I. Electrophoretic deposition of chiral polymers and composites. Colloids Surf B Biointerfaces. 2011;87:505-9 pubmed publisher

Opanasopit P, Tragulpakseerojn J, Apirakaramwong A, Ngawhirunpat T, Rojanarata T. Chitosan enhances transfection efficiency of cationic polypeptides/DNA complexes. Int J Pharm. 2011;410:161-8 pubmed publisher

Long H, Bock H, Lei T, Chai X, Yuan J, Herz J, et al. Identification of alternatively spliced Dab1 and Fyn isoforms in pig. BMC Neurosci. 2011;12:17 pubmed publisher

Mahairaki V, Lim S, Christopherson G, Xu L, Nasonkin I, Yu C, et al. Nanofiber matrices promote the neuronal differentiation of human embryonic stem cell-derived neural precursors in vitro. Tissue Eng Part A. 2011;17:855-63 pubmed publisher

Khadka D, Haynie D. Insoluble synthetic polypeptide mats from aqueous solution by electrospinning. ACS Appl Mater Interfaces. 2010;2:2728-32 pubmed publisher

Crews L, Adame A, Patrick C, DeLaney A, Pham E, Rockenstein E, et al. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. J Neurosci. 2010;30:12252-62 pubmed publisher

Giovagnoli S, Blasi P, Luca G, Fallarino F, Calvitti M, Mancuso F, et al. Bioactive long-term release from biodegradable microspheres preserves implanted ALG-PLO-ALG microcapsules from in vivo response to purified alginate. Pharm Res. 2010;27:285-95 pubmed publisher

Völlner F, Ernst W, Driemel O, Morsczeck C. A two-step strategy for neuronal differentiation in vitro of human dental follicle cells. Differentiation. 2009;77:433-41 pubmed publisher

Taura D, Noguchi M, Sone M, Hosoda K, Mori E, Okada Y, et al. Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett. 2009;583:1029-33 pubmed publisher

Shan Z, Lei L, Chen Y, Jin L, Shen J. [Programmed application of extracellular matrix promotes neural differentiation of mouse embryonic stem cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2008;28:2126-30 pubmed

Oh J, Recknor J, Recknor J, Mallapragada S, Sakaguchi D. Soluble factors from neocortical astrocytes enhance neuronal differentiation of neural progenitor cells from adult rat hippocampus on micropatterned polymer substrates. J Biomed Mater Res A. 2009;91:575-85 pubmed publisher

Hatada I, Namihira M, Morita S, Kimura M, Horii T, Nakashima K. Astrocyte-specific genes are generally demethylated in neural precursor cells prior to astrocytic differentiation. PLoS ONE. 2008;3:e3189 pubmed publisher

Bartosh T, Wang Z, Rosales A, Dimitrijevich S, Roque R. 3D-model of adult cardiac stem cells promotes cardiac differentiation and resistance to oxidative stress. J Cell Biochem. 2008;105:612-23 pubmed publisher

Leung A, Lawrie G, Nielsen L, Trau M. Synthesis and characterization of alginate/poly-L-ornithine/alginate microcapsules for local immunosuppression. J Microencapsul. 2008;25:387-98 pubmed publisher

Lu S, Gold M. Inflammation-induced increase in evoked calcium transients in subpopulations of rat dorsal root ganglion neurons. Neuroscience. 2008;153:279-88 pubmed publisher

O Toole M, Lamoureux P, Miller K. A physical model of axonal elongation: force, viscosity, and adhesions govern the mode of outgrowth. Biophys J. 2008;94:2610-20 pubmed publisher

Thanos C, Calafiore R, Basta G, Bintz B, Bell W, Hudak J, et al. Formulating the alginate-polyornithine biocapsule for prolonged stability: evaluation of composition and manufacturing technique. J Biomed Mater Res A. 2007;83:216-24 pubmed

Mann A, Khan M, Shukla V, Ganguli M. Atomic force microscopy reveals the assembly of potential DNA "nanocarriers" by poly-L-ornithine. Biophys Chem. 2007;129:126-36 pubmed

Thanos C, Schneider P, Bintz B, Jensen R, Bryant B, Bell W, et al. The in vitro expression and secretion of vascular endothelial growth factor from free and alginate-polyornithine encapsulated choroid plexus epithelium. Tissue Eng. 2007;13:747-56 pubmed

Harnett E, Alderman J, Wood T. The surface energy of various biomaterials coated with adhesion molecules used in cell culture. Colloids Surf B Biointerfaces. 2007;55:90-7 pubmed

Iacovitti L, Donaldson A, Marshall C, Suon S, Yang M. A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo. Brain Res. 2007;1127:19-25 pubmed

Cui Y, Shakesheff K, Adams G. Encapsulation of RIN-m5F cells within Ba2+ cross-linked alginate beads affects proliferation and insulin secretion. J Microencapsul. 2006;23:663-76 pubmed

Thanos C, Bintz B, Emerich D. Stability of alginate-polyornithine microcapsules is profoundly dependent on the site of transplantation. J Biomed Mater Res A. 2007;81:1-11 pubmed

Okuda T, Kawakami S, Maeie T, Niidome T, Yamashita F, Hashida M. Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration. J Control Release. 2006;114:69-77 pubmed

Ponce S, Orive G, Hernandez R, Gascón A, Pedraz J, de Haan B, et al. Chemistry and the biological response against immunoisolating alginate-polycation capsules of different composition. Biomaterials. 2006;27:4831-9 pubmed

Uebersax L, Fedele D, Schumacher C, Kaplan D, Merkle H, Boison D, et al. The support of adenosine release from adenosine kinase deficient ES cells by silk substrates. Biomaterials. 2006;27:4599-607 pubmed

Smith C. Cytoskeletal movements and substrate interactions during initiation of neurite outgrowth by sympathetic neurons in vitro. J Neurosci. 1994;14:384-98 pubmed