This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Phosphotyrosine antibody produced in mouse
catalog :
P4110
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PY20
application :
western blot, immunoprecipitation
citations: 26
Reference
Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
Klebanovych A, Sladkova V, Sulimenko T, Vosecká V, Capek M, Dráberová E, et al. Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1. Cells. 2019;8: pubmed publisher
Ceccon M, Mauri M, Massimino L, Giudici G, Piazza R, Gambacorti Passerini C, et al. Mitochondrial Hyperactivation and Enhanced ROS Production are Involved in Toxicity Induced by Oncogenic Kinases Over-Signaling. Cancers (Basel). 2018;10: pubmed publisher
Betarelli R, Rocco M, Yeste M, Fernández Novell J, Placci A, Azevedo Pereira B, et al. The achievement of boar sperm in vitro capacitation is related to an increase of disrupted disulphide bonds and intracellular reactive oxygen species levels. Andrology. 2018;6:781-797 pubmed publisher
Yang C, Sui Z, Xu T, Liu W, Wang X, Zeng X. Lipid raft‑associated β‑adducin participates in neutrophil migration. Mol Med Rep. 2018;18:1353-1360 pubmed publisher
Rocco M, Betarelli R, Placci A, Fernández Novell J, Spinaci M, Casao A, et al. Melatonin affects the motility and adhesiveness of in vitro capacitated boar spermatozoa via a mechanism that does not depend on intracellular ROS levels. Andrology. 2018;6:720-736 pubmed publisher
Pollard D, Berger C, So E, Yu L, Hadavizadeh K, Jennings P, et al. Broad-Spectrum Regulation of Nonreceptor Tyrosine Kinases by the Bacterial ADP-Ribosyltransferase EspJ. MBio. 2018;9: pubmed publisher
Teng Y, Pi W, Wang Y, Cowell J. WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling. Oncogene. 2016;35:4633-40 pubmed publisher
Patel A, Yamashita N, Ascano M, Bodmer D, Boehm E, Bodkin Clarke C, et al. RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome. Nat Commun. 2015;6:10119 pubmed publisher
Wakatsuki S, Furuno A, Ohshima M, Araki T. Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration. J Cell Biol. 2015;211:881-96 pubmed publisher
Almeida M, Mesquita F, Cruz R, Osorio H, Custodio R, Brito C, et al. Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection. J Biol Chem. 2015;290:8383-95 pubmed publisher
Urra J, Villaroel Espíndola F, Covarrubias A, Rodríguez Gil J, Ramírez Reveco A, Concha I. Presence and function of dopamine transporter (DAT) in stallion sperm: dopamine modulates sperm motility and acrosomal integrity. PLoS ONE. 2014;9:e112834 pubmed publisher
Shi Y, Wang J, Chandarlapaty S, Cross J, Thompson C, Rosen N, et al. PTEN is a protein tyrosine phosphatase for IRS1. Nat Struct Mol Biol. 2014;21:522-7 pubmed publisher
Wakatsuki S, Araki T, Sehara Fujisawa A. Neuregulin-1/glial growth factor stimulates Schwann cell migration by inducing ?5 ?1 integrin-ErbB2-focal adhesion kinase complex formation. Genes Cells. 2014;19:66-77 pubmed publisher
Luo J, Xu T, Li C, Ba X, Wang X, Jiang Y, et al. p85-RhoGDI2, a novel complex, is required for PSGL-1-induced ?1 integrin-mediated lymphocyte adhesion to VCAM-1. Int J Biochem Cell Biol. 2013;45:2764-73 pubmed publisher
Tang H, Duan C, Bleher R, Goldberg E. Human lactate dehydrogenase A (LDHA) rescues mouse Ldhc-null sperm function. Biol Reprod. 2013;88:96 pubmed publisher
Fukushima T, Nakamura Y, Yamanaka D, Shibano T, Chida K, Minami S, et al. Phosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation. J Biol Chem. 2012;287:29713-21 pubmed publisher
Phung B, Sun J, Schepsky A, Steingrimsson E, Rönnstrand L. C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation. PLoS ONE. 2011;6:e24064 pubmed publisher
Cieśla J, Fraczyk T, Rode W. Phosphorylation of basic amino acid residues in proteins: important but easily missed. Acta Biochim Pol. 2011;58:137-48 pubmed
Fukushima T, Nedachi T, Akizawa H, Akahori M, Hakuno F, Takahashi S. Distinct modes of activation of phosphatidylinositol 3-kinase in response to cyclic adenosine 3', 5'-monophosphate or insulin-like growth factor I play different roles in regulation of cyclin D1 and p27Kip1 in FRTL-5 cells. Endocrinology. 2008;149:3729-42 pubmed publisher
Hendriks W, Elson A, Harroch S, Stoker A. Protein tyrosine phosphatases: functional inferences from mouse models and human diseases. FEBS J. 2008;275:816-30 pubmed publisher
Ma W, Xia C, Ling P, Qiu M, Luo Y, Tan T, et al. Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes. Oncogene. 2001;20:1703-14 pubmed
Sarmay G, Pecht I, Gergely J. Protein-tyrosine kinase activity tightly associated with human type II Fc gamma receptors. Proc Natl Acad Sci U S A. 1994;91:4140-4 pubmed
Barry S, Critchley D. The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both pp125FAK and protein kinase C-delta to focal adhesions. J Cell Sci. 1994;107 ( Pt 7):2033-45 pubmed
Dvir A, Milner Y, Chomsky O, Gilon C, Gazit A, Levitzki A. The inhibition of EGF-dependent proliferation of keratinocytes by tyrphostin tyrosine kinase blockers. J Cell Biol. 1991;113:857-65 pubmed
Gutch M, Daly C, Reich N. Tyrosine phosphorylation is required for activation of an alpha interferon-stimulated transcription factor. Proc Natl Acad Sci U S A. 1992;89:11411-5 pubmed
product information
Catalog Number :
P4110
Product Name :
Monoclonal Anti-Phosphotyrosine antibody produced in mouse
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
unconjugated
Clone Name :
PY20
Isotype :
IgG2b
Product Description :
clone PY20, purified immunoglobulin, buffered aqueous glycerol solution
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA