Dedoni S, Marras L, Olianas M, Ingianni A, Onali P. Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis. Apoptosis. 2020;25:697-714 pubmed publisher

Dees S, Pontiggia L, Jasmin J, Sotgia F, Lisanti M, Mercier I. Essential role of STAT5a in DCIS formation and invasion following estrogen treatment. Aging (Albany NY). 2020;12:15104-15120 pubmed publisher

Chakraborty J, Sen S, Ghosh P, Jain A, Das S. Inhibition of multiple defense responsive pathways by CaWRKY70 transcription factor promotes susceptibility in chickpea under Fusarium oxysporum stress condition. BMC Plant Biol. 2020;20:319 pubmed publisher

Bonifacio M, Cerqueni G, Cometa S, Licini C, Sabbatini L, Mattioli Belmonte M, et al. Insights into Arbutin Effects on Bone Cells: Towards the Development of Antioxidant Titanium Implants. Antioxidants (Basel). 2020;9: pubmed publisher

Lim W, Kang C. Avenanthramide C suppresses hypoxia-induced cyclooxygenase-2 expression through sirtuin1 activation in non-small-cell lung cancer cells. Anim Cells Syst (Seoul). 2020;24:79-83 pubmed publisher

Cheng Y, Chou Y, Lai F, Jan M, Chang T, Jou I, et al. Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3β-mediated epileptic seizure activity in mice. Acta Neuropathol Commun. 2020;8:6 pubmed publisher

Huang S, Wu L, Lee M, Chang C, Cheng W, Fang Y, et al. A robust TDP-43 knock-in mouse model of ALS. Acta Neuropathol Commun. 2020;8:3 pubmed publisher

Verdura E, Schluter A, Fernández Eulate G, Ramos Martín R, Zulaica M, Planas Serra L, et al. A deep intronic splice variant advises reexamination of presumably dominant SPG7 Cases. Ann Clin Transl Neurol. 2020;7:105-111 pubmed publisher

Rubio R, Mohr I. Inhibition of ULK1 and Beclin1 by an α-herpesvirus Akt-like Ser/Thr kinase limits autophagy to stimulate virus replication. Proc Natl Acad Sci U S A. 2019;: pubmed publisher

Belli M, Secchi C, Stupack D, Shimasaki S. FOXO1 Negates the Cooperative Action of FOXL2C134W and SMAD3 in CYP19 Expression in HGrC1 Cells by Sequestering SMAD3. J Endocr Soc. 2019;3:2064-2081 pubmed publisher

Li T, Coan J, Krajewski K, Zhang L, Elias J, Strahl B, et al. Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules. Sci Rep. 2019;9:14226 pubmed publisher

Niikura Y, Kitagawa R, Fang L, Kitagawa K. CENP-A Ubiquitylation Is Indispensable to Cell Viability. Dev Cell. 2019;50:683-689.e6 pubmed publisher

Civciristov S, Huang C, Liu B, Marquez E, Gondin A, Schittenhelm R, et al. Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks. J Biol Chem. 2019;294:16198-16213 pubmed publisher

Uzquiano A, Cifuentes Diaz C, Jabali A, Romero D, Houllier A, Dingli F, et al. Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia. Cell Rep. 2019;28:1596-1611.e10 pubmed publisher

Waisner H, Kalamvoki M. The ICP0 Protein of Herpes Simplex Virus 1 (HSV-1) Downregulates Major Autophagy Adaptor Proteins Sequestosome 1 and Optineurin during the Early Stages of HSV-1 Infection. J Virol. 2019;93: pubmed publisher

Vredevoogd D, Kuilman T, Ligtenberg M, Boshuizen J, Stecker K, de Bruijn B, et al. Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold. Cell. 2019;178:585-599.e15 pubmed publisher

Caron M, Sharma A, O Sullivan J, Myler L, Ferreira M, Rodrigue A, et al. Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks. Nat Commun. 2019;10:2954 pubmed publisher

Park S, Safi R, Liu X, Baldi R, Liu W, Liu J, et al. Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer. Cell Rep. 2019;27:3587-3601.e4 pubmed publisher

Regué L, Minichiello L, Avruch J, Dai N. Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation. J Biol Chem. 2019;294:11944-11951 pubmed publisher

Tung Y, Peng K, Chen Y, Yen Y, Chang M, Thams S, et al. Mir-17∼92 Confers Motor Neuron Subtype Differential Resistance to ALS-Associated Degeneration. Cell Stem Cell. 2019;: pubmed publisher

Takashi Y, Kosako H, Sawatsubashi S, Kinoshita Y, Ito N, Tsoumpra M, et al. Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation. Proc Natl Acad Sci U S A. 2019;116:11418-11427 pubmed publisher

Brayford S, Kenny F, Hiratsuka T, Serna Morales E, Yolland L, Luchici A, et al. Heterotypic contact inhibition of locomotion can drive cell sorting between epithelial and mesenchymal cell populations. J Cell Sci. 2019;132: pubmed publisher

Zhang S, Bell E, Zhi H, Brown S, Imran S, Azuara V, et al. OCT4 and PAX6 determine the dual function of SOX2 in human ESCs as a key pluripotent or neural factor. Stem Cell Res Ther. 2019;10:122 pubmed publisher

Ni X, Kou W, Gu J, Wei P, Wu X, Peng H, et al. TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination. EMBO J. 2019;38: pubmed publisher

Steinbusch M, Caron M, Surtel D, van den Akker G, van Dijk P, Friedrich F, et al. The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion. J Biol Chem. 2019;294:5121-5136 pubmed publisher

Chang C, Zanini M, Shirvani H, Cheng J, Yu H, Feng C, et al. Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation. Dev Cell. 2019;48:184-199.e5 pubmed publisher

Abaev Schneiderman E, Admoni Elisha L, Levy D. SETD3 is a positive regulator of DNA-damage-induced apoptosis. Cell Death Dis. 2019;10:74 pubmed publisher

Tan S, Yu C, Sim Z, Low Z, Lee B, See F, et al. Pomegranate activates TFEB to promote autophagy-lysosomal fitness and mitophagy. Sci Rep. 2019;9:727 pubmed publisher

Klein C, Roussel G, Brun S, Rusu C, Patte Mensah C, Maitre M, et al. 5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer's disease. Acta Neuropathol Commun. 2018;6:136 pubmed publisher

Mathis C, Lascombe I, Monnien F, Bittard H, Kleinclauss F, Bedgedjian I, et al. Down-regulation of A-FABP predicts non-muscle invasive bladder cancer progression: investigation with a long term clinical follow-up. BMC Cancer. 2018;18:1239 pubmed publisher

Driessen R, Stassen O, Sjöqvist M, Suarez Rodriguez F, Grolleman J, Bouten C, et al. Shear stress induces expression, intracellular reorganization and enhanced Notch activation potential of Jagged1. Integr Biol (Camb). 2018;10:719-726 pubmed publisher

Bigoni Ordóñez G, Ortiz Sánchez E, Rosendo Chalma P, Valencia González H, Aceves C, Garcia Carranca A. Molecular iodine inhibits the expression of stemness markers on cancer stem-like cells of established cell lines derived from cervical cancer. BMC Cancer. 2018;18:928 pubmed publisher

Zhang F, Wang Y, Wang T, Yao L, Lam S, Huang X, et al. cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development. Proc Natl Acad Sci U S A. 2018;115:E9449-E9458 pubmed publisher

Morgan M, Fitzwalter B, Owens C, Powers R, Sottnik J, Gamez G, et al. Metastatic cells are preferentially vulnerable to lysosomal inhibition. Proc Natl Acad Sci U S A. 2018;115:E8479-E8488 pubmed publisher

Wang T, Reingruber J, Woodruff M, Majumder A, Camarena A, Artemyev N, et al. The PDE6 mutation in the rd10 retinal degeneration mouse model causes protein mislocalization and instability and promotes cell death through increased ion influx. J Biol Chem. 2018;293:15332-15346 pubmed publisher

Battaglia Hsu S, Ghemrawi R, Coelho D, Dreumont N, Mosca P, Hergalant S, et al. Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR. Nucleic Acids Res. 2018;46:7844-7857 pubmed publisher

Parker S, Stotland A, MacFarlane E, Wilson N, Orosco A, Venkatraman V, et al. Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice. Am J Physiol Heart Circ Physiol. 2018;315:H1112-H1126 pubmed publisher

Deschamps T, Kalamvoki M. Extracellular Vesicles Released by Herpes Simplex Virus 1-Infected Cells Block Virus Replication in Recipient Cells in a STING-Dependent Manner. J Virol. 2018;92: pubmed publisher

Rahnamoun H, Hong J, Sun Z, Lee J, Lu H, Lauberth S. Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4. J Biol Chem. 2018;293:13234-13246 pubmed publisher

Calcinotto A, Spataro C, Zagato E, Di Mitri D, Gil V, Crespo M, et al. IL-23 secreted by myeloid cells drives castration-resistant prostate cancer. Nature. 2018;559:363-369 pubmed publisher

Nedi T, White P, Coupar I, Irving H. Effect of the 5-HT4 receptor agonist tegaserod on the expression of GRK2 and GRK6 in the rat gastrointestinal tract. BMC Res Notes. 2018;11:362 pubmed publisher

Basu Ball W, Baker C, Neff J, Apfel G, Lagerborg K, Žun G, et al. Ethanolamine ameliorates mitochondrial dysfunction in cardiolipin-deficient yeast cells. J Biol Chem. 2018;293:10870-10883 pubmed publisher

Abou Faycal C, Brambilla E, Agorreta J, Lepeltier N, Jacquet T, Lemaître N, et al. The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma. Br J Cancer. 2018;118:1596-1608 pubmed publisher

Parisotto M, Grelet E, El Bizri R, Dai Y, Terzic J, Eckert D, et al. PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo. J Exp Med. 2018;215:1749-1763 pubmed publisher

Bolick D, Medeiros P, Ledwaba S, Lima A, Nataro J, Barry E, et al. Critical Role of Zinc in a New Murine Model of Enterotoxigenic Escherichia coli Diarrhea. Infect Immun. 2018;86: pubmed publisher

Sakr M, Li X, Sabeh F, Feinberg T, Tesmer J, Tang Y, et al. Tracking the Cartoon mouse phenotype: Hemopexin domain-dependent regulation of MT1-MMP pericellular collagenolytic activity. J Biol Chem. 2018;293:8113-8127 pubmed publisher

Sun J, Hu Q, Peng H, Peng C, Zhou L, Lu J, et al. The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43. J Biol Chem. 2018;293:8275-8284 pubmed publisher

Smith Moore S, Neil S, Fraefel C, Linden R, Bollen M, Rowe H, et al. Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome. Proc Natl Acad Sci U S A. 2018;115:E3529-E3538 pubmed publisher

Mathew M, Donaldson J. Distinct cargo-specific response landscapes underpin the complex and nuanced role of galectin-glycan interactions in clathrin-independent endocytosis. J Biol Chem. 2018;293:7222-7237 pubmed publisher

Porreca R, Glousker G, Awad A, Matilla Fernandez M, Gibaud A, Naucke C, et al. Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension. Nucleic Acids Res. 2018;46:4533-4545 pubmed publisher

Wang T, Du Q, Wu X, Niu Y, Guan L, Wang Z, et al. Porcine MKRN1 Modulates the Replication and Pathogenesis of Porcine Circovirus Type 2 by Inducing Capsid Protein Ubiquitination and Degradation. J Virol. 2018;92: pubmed publisher

Behrens G, Winzen R, Rehage N, Dörrie A, Barsch M, Hoffmann A, et al. A translational silencing function of MCPIP1/Regnase-1 specified by the target site context. Nucleic Acids Res. 2018;46:4256-4270 pubmed publisher

Baggio L, Yusta B, Mulvihill E, Cao X, Streutker C, Butany J, et al. GLP-1 Receptor Expression Within the Human Heart. Endocrinology. 2018;159:1570-1584 pubmed publisher

Chen J, Lin W, Chen Z, Liu H. PARP-1-dependent recruitment of cold-inducible RNA-binding protein promotes double-strand break repair and genome stability. Proc Natl Acad Sci U S A. 2018;115:E1759-E1768 pubmed publisher

Liu J, Tang L, Wang Y, Lu S, Zhang E, Wang Z, et al. Identification of MAVS as a Novel Risk Factor for the Development of Osteoarthritis. Aging Dis. 2018;9:40-50 pubmed publisher

Uchino Y, Woodward A, Mauris J, Peterson K, Verma P, Nilsson U, et al. Galectin-3 is an amplifier of the interleukin-1β-mediated inflammatory response in corneal keratinocytes. Immunology. 2018;154:490-499 pubmed publisher

Leo D, Sukhanov I, Zoratto F, Illiano P, Caffino L, Sanna F, et al. Pronounced Hyperactivity, Cognitive Dysfunctions, and BDNF Dysregulation in Dopamine Transporter Knock-out Rats. J Neurosci. 2018;38:1959-1972 pubmed publisher

Misra A, Gleeson E, Wang W, Ye C, Zhou P, Kimata J. Glycosyl-Phosphatidylinositol-Anchored Anti-HIV Env Single-Chain Variable Fragments Interfere with HIV-1 Env Processing and Viral Infectivity. J Virol. 2018;92: pubmed publisher

Lim J, Bang Y, Choi J, Han A, Kwon M, Liu K, et al. LRRK2 G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT1A Receptor Upregulation in Mice. J Neurosci. 2018;38:1611-1621 pubmed publisher

Wang D, Sun X, Wei Y, Liang H, Yuan M, Jin F, et al. Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level. Nucleic Acids Res. 2018;46:2012-2029 pubmed publisher

Hu Y, Semova I, Sun X, Kang H, Chahar S, Hollenberg A, et al. Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways. J Biol Chem. 2018;293:2006-2014 pubmed publisher

Rodarte E, Ramos M, Davalos A, Moreira D, Moreno D, Cardenas E, et al. Munc13 proteins control regulated exocytosis in mast cells. J Biol Chem. 2018;293:345-358 pubmed publisher

Xue L, Liu L, Huang J, Wen J, Yang R, Bo L, et al. Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Activates Type I Interferon Signals in Lupus Nephritis. Biomed Res Int. 2017;2017:4927376 pubmed publisher

Zhao C, Fang J, Li C, Zhang M. Connexin43 and AMPK Have Essential Role in Resistance to Oxidative Stress Induced Necrosis. Biomed Res Int. 2017;2017:3962173 pubmed publisher

Tangudu N, Alan B, Vinchi F, Woerle K, Lai D, Vettorazzi S, et al. Scavenging reactive oxygen species production normalizes ferroportin expression and ameliorates cellular and systemic iron disbalances in hemolytic mouse model. Antioxid Redox Signal. 2017;: pubmed publisher

Rossi M, Saverioni D, Di Bari M, Baiardi S, Lemstra A, Pirisinu L, et al. Atypical Creutzfeldt-Jakob disease with PrP-amyloid plaques in white matter: molecular characterization and transmission to bank voles show the M1 strain signature. Acta Neuropathol Commun. 2017;5:87 pubmed publisher

Short S, Kondo J, Smalley Freed W, Takeda H, Dohn M, Powell A, et al. p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia. J Clin Invest. 2017;127:4462-4476 pubmed publisher

Conway L, Cardarelli R, Moore Y, Jones K, McWilliams L, Baker D, et al. N-Ethylmaleimide increases KCC2 cotransporter activity by modulating transporter phosphorylation. J Biol Chem. 2017;292:21253-21263 pubmed publisher

Maximiano W, da Silva E, Santana A, de Oliveira P, Jamur M, Oliver C. Mast Cell Mediators Inhibit Osteoblastic Differentiation and Extracellular Matrix Mineralization. J Histochem Cytochem. 2017;:22155417734174 pubmed publisher

Padilla Benavides T, Nasipak B, Paskavitz A, Haokip D, Schnabl J, Nickerson J, et al. Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition. J Biol Chem. 2017;292:18592-18607 pubmed publisher

Lucas Hourani M, Dauzonne D, Munier Lehmann H, Khiar S, Nisole S, Dairou J, et al. Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response. Antimicrob Agents Chemother. 2017;61: pubmed publisher

Hosomi S, Grootjans J, Tschurtschenthaler M, Krupka N, Matute J, Flak M, et al. Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation. J Exp Med. 2017;214:2985-2997 pubmed publisher

Spaeth J, Gupte M, Perelis M, Yang Y, CYPHERT H, Guo S, et al. Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning. Diabetes. 2017;66:2830-2839 pubmed publisher

Hamon A, Masson C, Bitard J, Gieser L, Roger J, Perron M. Retinal Degeneration Triggers the Activation of YAP/TEAD in Reactive Müller Cells. Invest Ophthalmol Vis Sci. 2017;58:1941-1953 pubmed publisher

Lemler D, Lynch M, Tesfay L, Deng Z, Paul B, Wang X, et al. DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms. Breast Cancer Res. 2017;19:25 pubmed publisher

Eliscovich C, Shenoy S, Singer R. Imaging mRNA and protein interactions within neurons. Proc Natl Acad Sci U S A. 2017;114:E1875-E1884 pubmed publisher

Augustine T, Chaudhary P, Gupta K, Islam S, Ghosh P, Santra M, et al. Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCFcyclin F E3 Ligase Machinery. J Biol Chem. 2017;292:5349-5363 pubmed publisher

Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, et al. Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death. J Biol Chem. 2017;292:4727-4742 pubmed publisher

Ren Y, Zhao P, Liu J, Yuan Y, Cheng Q, Zuo Y, et al. Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus. PLoS Pathog. 2016;12:e1005764 pubmed publisher

Faltermeier C, Drake J, Clark P, Smith B, Zong Y, Volpe C, et al. Functional screen identifies kinases driving prostate cancer visceral and bone metastasis. Proc Natl Acad Sci U S A. 2016;113:E172-81 pubmed publisher

Yoshikawa R, Izumi T, Yamada E, Nakano Y, Misawa N, Ren F, et al. A Naturally Occurring Domestic Cat APOBEC3 Variant Confers Resistance to Feline Immunodeficiency Virus Infection. J Virol. 2016;90:474-85 pubmed publisher

Roque A, Orrego M, Ponte I, Suau P. The preferential binding of histone H1 to DNA scaffold-associated regions is determined by its C-terminal domain. Nucleic Acids Res. 2004;32:6111-9 pubmed