This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Phosphoserine antibody produced in mouse
catalog :
P3430
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PSR-45
reactivity :
mouse, rat
application :
western blot, immunohistochemistry - paraffin section
citations: 53
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig 5c
Oya K, Ishida K, Nishida T, Sato S, Kishino M, Hirose K, et al. Immunohistochemical analysis of dentin matrix protein 1 (Dmp1) phosphorylation by Fam20C in bone: implications for the induction of biomineralization. Histochem Cell Biol. 2017;147:341-351 pubmed publisher
  • western blot; mouse
Miyagishima H, Isono K, Fujimura Y, Iyo M, Takihara Y, Masumoto H, et al. Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase. Histochem Cell Biol. 2003;120:111-9 pubmed
Matsuoka H, Harada K, Mashima K, Inoue M. Muscarinic receptor stimulation induces TASK1 channel endocytosis through a PKC-Pyk2-Src pathway in PC12 cells. Cell Signal. 2020;65:109434 pubmed publisher
Poon J, Fries A, Wessel G, Yajima M. Evolutionary modification of AGS protein contributes to formation of micromeres in sea urchins. Nat Commun. 2019;10:3779 pubmed publisher
Amaya E, Alarcón L, Martín Tapia D, Cuellar Perez F, Cano Cortina M, Ortega Olvera J, et al. Activation of the Ca2+ sensing receptor and the PKC/WNK4 downstream signaling cascade induces incorporation of ZO-2 to tight junctions and its separation from 14-3-3. Mol Biol Cell. 2019;30:2377-2398 pubmed publisher
Jing X, Wang X, Zhang T, Zhu W, Fang Y, Wu H, et al. Cell cycle-dependent phosphorylation of PRPS1 fuels nucleotide synthesis and promotes tumorigenesis. Cancer Res. 2019;: pubmed publisher
Ahmad S, She Z, Kraatz H. Electrochemical studies of human nAChR a7 subunit phosphorylation by kinases PKA, PKC and Src. Anal Biochem. 2019;574:46-56 pubmed publisher
Sager R, Woodford M, Backe S, Makedon A, Baker Williams A, DiGregorio B, et al. Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90. Cell Rep. 2019;26:1344-1356.e5 pubmed publisher
Zemoura K, Balakrishnan K, Grampp T, Benke D. Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) β-Dependent Phosphorylation of GABAB1 Triggers Lysosomal Degradation of GABAB Receptors via Mind Bomb-2 (MIB2)-Mediated Lys-63-Linked Ubiquitination. Mol Neurobiol. 2019;56:1293-1309 pubmed publisher
Guo H, Nolan T, Song G, Liu S, Xie Z, Chen J, et al. FERONIA Receptor Kinase Contributes to Plant Immunity by Suppressing Jasmonic Acid Signaling in Arabidopsis thaliana. Curr Biol. 2018;28:3316-3324.e6 pubmed publisher
Priyadarshini R, Hussain M, Attri P, Kaur E, Tripathi V, Priya S, et al. BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor. Cell Rep. 2018;24:947-961.e7 pubmed publisher
Peng Y, Chen L, Li S, Zhang Y, Xu R, Liu Z, et al. BRI1 and BAK1 interact with G proteins and regulate sugar-responsive growth and development in Arabidopsis. Nat Commun. 2018;9:1522 pubmed publisher
Park S, Yoon S, Sun E, Zhou R, Bae J, Seo Y, et al. Glycoprotein 90K Promotes E-Cadherin Degradation in a Cell Density-Dependent Manner via Dissociation of E-Cadherin-p120-Catenin Complex. Int J Mol Sci. 2017;18: pubmed publisher
Liu J, Wang G, Duan Y, Dai Y, Bao Y, Hu M, et al. Modulation of the Nur77-Bcl-2 apoptotic pathway by p38? MAPK. Oncotarget. 2017;8:69731-69745 pubmed publisher
Pandey S, Talukdar I, Jain B, Tanti G, Goswami S. GSK3β and ERK regulate the expression of 78 kDa SG2NA and ectopic modulation of its level affects phases of cell cycle. Sci Rep. 2017;7:7555 pubmed publisher
Kim S, Kim H, Park M, Cho S, Goughnour P, Han D, et al. Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells. J Cell Biol. 2017;216:2201-2216 pubmed publisher
Fujii N, Matsuo Y, Matsunaga T, Endo S, Sakai H, Yamaguchi M, et al. Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells. J Biol Chem. 2016;291:24787-24799 pubmed
Patel S, Trivedi G, Darie C, Clarkson B. The possible roles of B-cell novel protein-1 (BCNP1) in cellular signalling pathways and in cancer. J Cell Mol Med. 2017;21:456-466 pubmed publisher
Xia P, Zhou J, Song X, Wu B, Liu X, Li D, et al. Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction. J Mol Cell Biol. 2014;6:240-54 pubmed publisher
Bakshi K, Parihar R, Goswami S, Walsh M, Friedman E, Wang H. Prenatal cocaine exposure uncouples mGluR1 from Homer1 and Gq Proteins. PLoS ONE. 2014;9:e91671 pubmed publisher
Kim H, Kim S, Park H, Lee J, Yoon J, Choi S, et al. Functional interplay between Aurora B kinase and Ssu72 phosphatase regulates sister chromatid cohesion. Nat Commun. 2013;4:2631 pubmed publisher
Quirós M, Alarcón L, Ponce A, Giannakouros T, Gonzalez Mariscal L. The intracellular fate of zonula occludens 2 is regulated by the phosphorylation of SR repeats and the phosphorylation/O-GlcNAcylation of S257. Mol Biol Cell. 2013;24:2528-43 pubmed publisher
Ferro F, Spelat R, D Aurizio F, Puppato E, Pandolfi M, Beltrami A, et al. Dental pulp stem cells differentiation reveals new insights in Oct4A dynamics. PLoS ONE. 2012;7:e41774 pubmed publisher
Barber M, Hendrickx A, Beullens M, Ceulemans H, Oxley D, Thelen S, et al. The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1?. Biochem J. 2012;443:173-83 pubmed publisher
Bakshi K, Kosciuk M, Nagele R, Friedman E, Wang H. Prenatal cocaine exposure increases synaptic localization of a neuronal RasGEF, GRASP-1 via hyperphosphorylation of AMPAR anchoring protein, GRIP. PLoS ONE. 2011;6:e25019 pubmed publisher
Cieśla J, Fraczyk T, Rode W. Phosphorylation of basic amino acid residues in proteins: important but easily missed. Acta Biochim Pol. 2011;58:137-48 pubmed
Zorina A, Stepanchenko N, Novikova G, Sinetova M, Panichkin V, Moshkov I, et al. Eukaryotic-like Ser/Thr protein kinases SpkC/F/K are involved in phosphorylation of GroES in the Cyanobacterium synechocystis. DNA Res. 2011;18:137-51 pubmed publisher
Ching T, Chiang W, Chen C, Hsu A. Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity. Aging Cell. 2011;10:506-19 pubmed publisher
Tansi F, Blanchard V, Berger M, Tauber R, Reutter W, Fan H. Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cells. Virol J. 2010;7:267 pubmed publisher
Chen F, Ellis E, Strom S, Shneider B. ATPase Class I Type 8B Member 1 and protein kinase C zeta induce the expression of the canalicular bile salt export pump in human hepatocytes. Pediatr Res. 2010;67:183-7 pubmed publisher
Bakshi K, Gennaro S, CHAN C, Kosciuk M, Liu J, Stucky A, et al. Prenatal cocaine reduces AMPA receptor synaptic expression through hyperphosphorylation of the synaptic anchoring protein GRIP. J Neurosci. 2009;29:6308-19 pubmed publisher
Bodrato N, Franco L, Fresia C, Guida L, Usai C, Salis A, et al. Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose. J Biol Chem. 2009;284:14777-87 pubmed publisher
Yellaturu C, Deng X, Cagen L, Wilcox H, Mansbach C, Siddiqi S, et al. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles. J Biol Chem. 2009;284:7518-32 pubmed publisher
Bruzzone S, Bodrato N, Usai C, Guida L, Moreschi I, Nano R, et al. Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger. J Biol Chem. 2008;283:32188-97 pubmed publisher
Bardales J, Hellman U, Villamarin J. Identification of multiple isoforms of the cAMP-dependent protein kinase catalytic subunit in the bivalve mollusc Mytilus galloprovincialis. FEBS J. 2008;275:4479-89 pubmed publisher
Hendriks W, Elson A, Harroch S, Stoker A. Protein tyrosine phosphatases: functional inferences from mouse models and human diseases. FEBS J. 2008;275:816-30 pubmed publisher
Pluemsampant S, Safronova O, Nakahama K, Morita I. Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors. Int J Cancer. 2008;122:333-41 pubmed
Mishra S, Melino G, Murphy L. Transglutaminase 2 kinase activity facilitates protein kinase A-induced phosphorylation of retinoblastoma protein. J Biol Chem. 2007;282:18108-15 pubmed
Taylor N. Identification of cellulose synthase AtCesA7 (IRX3) in vivo phosphorylation sites--a potential role in regulating protein degradation. Plant Mol Biol. 2007;64:161-71 pubmed
Lattuada D, Vigano P, Mangioni S, Sassone J, Di Francesco S, Vignali M, et al. Accumulation of retinoid X receptor-alpha in uterine leiomyomas is associated with a delayed ligand-dependent proteasome-mediated degradation and an alteration of its transcriptional activity. Mol Endocrinol. 2007;21:602-12 pubmed
Yue W, Gershburg E, Pagano J. Hyperphosphorylation of EBNA2 by Epstein-Barr virus protein kinase suppresses transactivation of the LMP1 promoter. J Virol. 2005;79:5880-5 pubmed
Purdom S, Chen Q. Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts. J Pharmacol Exp Ther. 2005;312:1179-86 pubmed
Efendiev R, Krmar R, Ogimoto G, Zwiller J, Tripodi G, Katz A, et al. Hypertension-linked mutation in the adducin alpha-subunit leads to higher AP2-mu2 phosphorylation and impaired Na+,K+-ATPase trafficking in response to GPCR signals and intracellular sodium. Circ Res. 2004;95:1100-8 pubmed
Slavin D, Koritschoner N, Prieto C, López Díaz F, Chatton B, Bocco J. A new role for the Kruppel-like transcription factor KLF6 as an inhibitor of c-Jun proto-oncoprotein function. Oncogene. 2004;23:8196-205 pubmed
Tanaka T, Akatsuka S, Ozeki M, Shirase T, Hiai H, Toyokuni S. Redox regulation of annexin 2 and its implications for oxidative stress-induced renal carcinogenesis and metastasis. Oncogene. 2004;23:3980-9 pubmed
Dudognon P, Maeder Garavaglia C, Carpentier J, Paccaud J. Regulation of a COPII component by cytosolic O-glycosylation during mitosis. FEBS Lett. 2004;561:44-50 pubmed
Alsheikh M, Heyen B, Randall S. Ion binding properties of the dehydrin ERD14 are dependent upon phosphorylation. J Biol Chem. 2003;278:40882-9 pubmed
Matsushima Nishiwaki R, Okuno M, Takano Y, Kojima S, Friedman S, Moriwaki H. Molecular mechanism for growth suppression of human hepatocellular carcinoma cells by acyclic retinoid. Carcinogenesis. 2003;24:1353-9 pubmed
Warke V, Nambiar M, Krishnan S, Tenbrock K, Geller D, Koritschoner N, et al. Transcriptional activation of the human inducible nitric-oxide synthase promoter by Kruppel-like factor 6. J Biol Chem. 2003;278:14812-9 pubmed
Stronati L, Gensabella G, Lamberti C, Barattini P, Frasca D, Tanzarella C, et al. Expression and DNA binding activity of the Ku heterodimer in bladder carcinoma. Cancer. 2001;92:2484-92 pubmed
Chen M, Chang S, Huang H, Chen J. A protein kinase activity associated with Epstein-Barr virus BGLF4 phosphorylates the viral early antigen EA-D in vitro. J Virol. 2000;74:3093-104 pubmed
Sarmay G, Pecht I, Gergely J. Protein-tyrosine kinase activity tightly associated with human type II Fc gamma receptors. Proc Natl Acad Sci U S A. 1994;91:4140-4 pubmed
Thomas M, Gronowski A, Berry S, Bergad P, Rotwein P. Growth hormone rapidly activates rat serine protease inhibitor 2.1 gene transcription and induces a DNA-binding activity distinct from those of Stat1, -3, and -4. Mol Cell Biol. 1995;15:12-8 pubmed
product information
Catalog Number :
P3430
Product Name :
Monoclonal Anti-Phosphoserine antibody produced in mouse
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
unconjugated
Clone Name :
PSR-45
Isotype :
IgG1
Product Description :
clone PSR-45, ascites fluid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA