Yun C, Roh E, Kim S, Han J, Lee J, Jung D, et al. Stem Cell Factor-Inducible MITF-M Expression in Therapeutics for Acquired Skin Hyperpigmentation. Theranostics. 2020;10:340-352 pubmed publisher

Sapio L, Salzillo A, Illiano M, Ragone A, Spina A, Chiosi E, et al. Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells. J Cell Physiol. 2020;235:3741-3752 pubmed publisher

Wu L, Gong Z, Wang H, Zhou Z, Zhang M, Liu C, et al. TSPO ligands prevent the proliferation of vascular smooth muscle cells and attenuate neointima formation through AMPK activation. Acta Pharmacol Sin. 2020;41:34-46 pubmed publisher

Nalinratana N, Meksuriyen D, Ongpipattanakul B. Asiaticoside but not its aglycone exhibits neuritogenicity through TrkA receptor signaling: a bridge between ERK1/2-CREB and Akt-GSK3β/RhoA. Neuroreport. 2019;30:1261-1270 pubmed publisher

Hoffmann M, Gogola J, Ptak A. Apelin abrogates the stimulatory effects of 17β-estradiol and insulin-like growth factor-1 on proliferation of epithelial and granulosa ovarian cancer cell lines via crosstalk between APLNR and ERα/IGF1R. Mol Biol Rep. 2019;46:6325-6338 pubmed publisher

Crescitelli M, Rauschemberger M, Cepeda S, Sandoval M, Massheimer V. Role of estrone on the regulation of osteoblastogenesis. Mol Cell Endocrinol. 2019;498:110582 pubmed publisher

Dal Cim T, Poluceno G, Lanznaster D, de Oliveira K, Nedel C, Tasca C. Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A1 and A2A adenosine receptors and PI3K, MEK, and PKC pathways. Purinergic Signal. 2019;15:465-476 pubmed publisher

Piersma S, Pak Wittel M, Lin A, Plougastel Douglas B, Yokoyama W. Activation Receptor-Dependent IFN-γ Production by NK Cells Is Controlled by Transcription, Translation, and the Proteasome. J Immunol. 2019;203:1981-1988 pubmed publisher

Luo S, Kang S, Wang Z, Liu X, Day J, Wu Z, et al. Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease. J Neurosci. 2019;39:7291-7305 pubmed publisher

Nagashima H, Mahlakõiv T, Shih H, Davis F, Meylan F, Huang Y, et al. Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation. Immunity. 2019;51:682-695.e6 pubmed publisher

Shan C, Sun H, Zhou Y, Wang W. Jasmonic acid-induced hydrogen sulfide activates MEK1/2 in regulating the redox state of ascorbate in Arabidopsis thaliana leaves. Plant Signal Behav. 2019;14:1629265 pubmed publisher

Finetti F, Cassioli C, Cianfanelli V, Onnis A, Paccagnini E, Kabanova A, et al. The intraflagellar transport protein IFT20 controls lysosome biogenesis by regulating the post-Golgi transport of acid hydrolases. Cell Death Differ. 2019;: pubmed publisher

Markworth R, Adolfs Y, Dambeck V, Steinbeck L, Lizé M, Pasterkamp R, et al. Sensory axon growth requires spatiotemporal integration of CaSR and TrkB signalling. J Neurosci. 2019;: pubmed publisher

Cheng M, Yang L, Fan M, An S, Li J. Proatherogenic stimuli induce HuR in atherosclerosis through MAPK/ErK pathway. Am J Transl Res. 2019;11:2317-2327 pubmed

Verdejo Torres O, Flores Maldonado C, Padilla Benavides T, Campos Blázquez J, Lara Lemus R, Perez Salazar E, et al. Ouabain Accelerates Collective Cell Migration Through a cSrc and ERK1/2 Sensitive Metalloproteinase Activity. J Membr Biol. 2019;: pubmed publisher

Majeed Y, Upadhyay R, Alhousseiny S, Taha T, Musthak A, Shaheen Y, et al. Potent and PPARα-independent anti-proliferative action of the hypolipidemic drug fenofibrate in VEGF-dependent angiosarcomas in vitro. Sci Rep. 2019;9:6316 pubmed publisher

Wang Y, Chen W, Lai Y, Chen Y, Wu M, Kuo C, et al. Influence of Tea Consumption on the Development of Second Esophageal Neoplasm in Patients with Head and Neck Cancer. Cancers (Basel). 2019;11: pubmed publisher

Graziani F, Pinton P, Olleik H, Pujol A, Nicoletti C, Sicre M, et al. Deoxynivalenol inhibits the expression of trefoil factors (TFF) by intestinal human and porcine goblet cells. Arch Toxicol. 2019;93:1039-1049 pubmed publisher

Yun C, Hong S, Lee Y, Lee J, Jung D, Kim G, et al. Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary Disorder. Theranostics. 2019;9:646-660 pubmed publisher

Meyer C, Wooten D, Paudel B, BAUER J, Hardeman K, Westover D, et al. Quantifying Drug Combination Synergy along Potency and Efficacy Axes. Cell Syst. 2019;8:97-108.e16 pubmed publisher

Wang L, Zhou Y, Chen Z, Sun L, Wu J, Li H, et al. PLCβ2 negatively regulates the inflammatory response to virus infection by inhibiting phosphoinositide-mediated activation of TAK1. Nat Commun. 2019;10:746 pubmed publisher

Naito K, Kurihara K, Moteki H, Kimura M, Natsume H, Ogihara M. Effect of Selective Serotonin (5-HT)2B Receptor Agonist BW723C86 on Epidermal Growth Factor/Transforming Growth Factor-α Receptor Tyrosine Kinase and Ribosomal p70 S6 Kinase Activities in Primary Cultures of Adult Rat Hepatocytes. Biol Pharm Bull. 2019;42:631-637 pubmed publisher

Ting C, Lee K, Wu S, Feng P, Chan Y, Chen Y, et al. FOSB⁻PCDHB13 Axis Disrupts the Microtubule Network in Non-Small Cell Lung Cancer. Cancers (Basel). 2019;11: pubmed publisher

Kim J, Pajarillo E, Rizor A, Son D, Lee J, Aschner M, et al. LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia. PLoS ONE. 2019;14:e0210248 pubmed publisher

Calvo N, Carriere P, Martín M, Gigola G, Gentili C. PTHrP treatment of colon cancer cells promotes tumor associated-angiogenesis by the effect of VEGF. Mol Cell Endocrinol. 2019;483:50-63 pubmed publisher

Treppiedi D, Giardino E, Catalano R, Mangili F, Vercesi P, Sala E, et al. Somatostatin analogs regulate tumor corticotrophs growth by reducing ERK1/2 activity. Mol Cell Endocrinol. 2019;483:31-38 pubmed publisher

Manickam G, Moffatt P, Murshed M. Role of SMPD3 during Bone Fracture Healing and Regulation of Its Expression. Mol Cell Biol. 2019;39: pubmed publisher

Lou Q, Hu Y, Ma Y, Dong Z. RNA interference may suppress stress granule formation by preventing argonaute 2 recruitment. Am J Physiol Cell Physiol. 2019;316:C81-C91 pubmed publisher

Mazucanti C, Kawamoto E, Mattson M, Scavone C, Camandola S. Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis. J Cereb Blood Flow Metab. 2019;39:1544-1556 pubmed publisher

Wei Y, Ma R, Zhang J, Wu X, Yu G, Hu X, et al. Excessive periostin expression and Th2 response in patients with nasal polyps: association with asthma. J Thorac Dis. 2018;10:6585-6597 pubmed publisher

Choi J, Jang A, Kim D, Park M, Lim S, Kim M, et al. PRMT1 mediates RANKL-induced osteoclastogenesis and contributes to bone loss in ovariectomized mice. Exp Mol Med. 2018;50:111 pubmed publisher

Sabharwal S, Rosen D, Grein J, Tedesco D, Joyce Shaikh B, Ueda R, et al. GITR Agonism Enhances Cellular Metabolism to Support CD8+ T-cell Proliferation and Effector Cytokine Production in a Mouse Tumor Model. Cancer Immunol Res. 2018;6:1199-1211 pubmed publisher

Martín M, Gigola G, Zwenger A, Carriquiriborde M, Gentil F, Gentili C. Potential therapeutic targets for growth arrest of colorectal cancer cells exposed to PTHrP. Mol Cell Endocrinol. 2018;478:32-44 pubmed publisher

Dong Y, Wu Z, He M, Chen Y, Chen Y, Shen X, et al. ADAM9 mediates the interleukin-6-induced Epithelial-Mesenchymal transition and metastasis through ROS production in hepatoma cells. Cancer Lett. 2018;421:1-14 pubmed publisher

Maugeri G, D Amico A, Rasà D, Saccone S, Federico C, Magro G, et al. Caffeine Effect on HIFs/VEGF Pathway in Human Glioblastoma Cells Exposed to Hypoxia. Anticancer Agents Med Chem. 2018;18:1432-1439 pubmed publisher

Park K, Mitra A, Rahat B, Kim K, Pfeifer K. Loss of imprinting mutations define both distinct and overlapping roles for misexpression of IGF2 and of H19 lncRNA. Nucleic Acids Res. 2017;45:12766-12779 pubmed publisher

Lu C, Hung C, Jean W, Lin T, Huang S, Wang S. Lycopene depresses glutamate release through inhibition of voltage-dependent Ca ²⁺ entry and protein kinase C in rat cerebrocortical nerve terminals. Can J Physiol Pharmacol. 2017;: pubmed publisher

Im D, Lee J, Lee J, Shin H, No K, Park S, et al. Inhibition of collagenase and melanogenesis by ethanol extracts of Orostachys japonicus A. Berger: possible involvement of Erk and Akt signaling pathways in melanoma cells. Acta Biochim Biophys Sin (Shanghai). 2017;49:945-953 pubmed publisher

Sheng X, Tu H, Chien W, Kang K, Lu D, Liou H, et al. Antagonism of proteasome inhibitor-induced heme oxygenase-1 expression by PINK1 mutation. PLoS ONE. 2017;12:e0183076 pubmed publisher

Martin L, Smith S, Khoutorsky A, Magnussen C, Samoshkin A, Sorge R, et al. Epiregulin and EGFR interactions are involved in pain processing. J Clin Invest. 2017;127:3353-3366 pubmed publisher

Lee S, Choi B. Involvement of NLRP10 in IL-1? induction of oral epithelial cells by periodontal pathogens. Innate Immun. 2017;23:569-577 pubmed publisher

Vyas F, Nelson C, Freeman F, Boocock D, Hargreaves A, Dickenson J. β2-adrenoceptor-induced modulation of transglutaminase 2 transamidase activity in cardiomyoblasts. Eur J Pharmacol. 2017;813:105-121 pubmed publisher

Sim M, Ham J, Lee M. Young leaves of reed (Phragmites communis) suppress melanogenesis and oxidative stress in B16F10 melanoma cells. Biomed Pharmacother. 2017;93:165-171 pubmed publisher

Fang W, Bi D, Zheng R, Cai N, Xu H, Zhou R, et al. Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages. Sci Rep. 2017;7:1663 pubmed publisher

Ren H, Yin X, Yu H, Xiao H. Stevioside induced cytotoxicity in colon cancer cells via reactive oxygen species and mitogen-activated protein kinase signaling pathways-mediated apoptosis. Oncol Lett. 2017;13:2337-2343 pubmed publisher

Zhao B, Hu M, Wu H, Ren C, Wang J, Cui S. Tenascin-C expression and its associated pathway in BMSCs following co-culture with mechanically stretched ligament fibroblasts. Mol Med Rep. 2017;15:2465-2472 pubmed publisher

Wang Z, Shao M, Liu Y. Promotion of Wilms' tumor cells migration and invasion by mono-2-ethyhexyl phthalate (MEHP) via activation of NF-?B signals. Chem Biol Interact. 2017;270:1-8 pubmed publisher

Calvo N, Carriere P, Martín M, Gentili C. RSK activation via ERK modulates human colon cancer cells response to PTHrP. J Mol Endocrinol. 2017;59:13-27 pubmed publisher

Ma A, He M, Bai J, Wong M, Ko W, Wong A. Dual Role of Insulin in Spexin Regulation: Functional Link Between Food Intake and Spexin Expression in a Fish Model. Endocrinology. 2017;158:560-577 pubmed publisher

Wang Y, Zhao M, Liu J, Ni J, Jiao Y, Bai C. Up regulation of IL-6 is involved in di (2-ethylhexyl) phthalate (DEHP) induced migration and invasion of non small cell lung cancer (NSCLC) cells. Biomed Pharmacother. 2017;89:1037-1044 pubmed publisher

Suares A, Mori Sequeiros Garcia M, Paz C, Gonzalez Pardo V. Antiproliferative effects of Bortezomib in endothelial cells transformed by viral G protein-coupled receptor associated to Kaposi's sarcoma. Cell Signal. 2017;32:124-132 pubmed publisher

Lu C, Lin T, Chang C, Huang S, Wang S. Ciproxifan, a histamine H3 receptor antagonist and inverse agonist, presynaptically inhibits glutamate release in rat hippocampus. Toxicol Appl Pharmacol. 2017;319:12-21 pubmed publisher

Sallam M, El Gowilly S, Abdel Galil A, El Mas M. Cyclosporine counteracts endotoxemia-evoked reductions in blood pressure and cardiac autonomic dysfunction via central sGC/MAPKs signaling in rats. Eur J Pharmacol. 2017;797:143-152 pubmed publisher

Campana W, Mantuano E, Azmoon P, Henry K, Banki M, Kim J, et al. Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells. FASEB J. 2017;31:1744-1755 pubmed publisher

Chang C, Liao K, Chen C. 2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-?B Pathways in RAW 264.7 Macrophage Cells. PLoS ONE. 2017;12:e0168945 pubmed publisher

He P, Kawamura H, Takemoto M, Maezawa Y, Ishikawa T, Ishibashi R, et al. Combination of cilostazol and probucol protected podocytes from lipopolysaccharide-induced injury by both anti-inflammatory and anti-oxidative mechanisms. J Nephrol. 2017;30:531-541 pubmed publisher

Lee D, Shin M, Shin K. Characterization of Macrophage-Activating Polysaccharide Isolated from Fermented Brown Rice. J Med Food. 2016;19:1147-1154 pubmed

Rizwan A, Zhan X, Zamponi G, Turner R. Long-Term Potentiation at the Mossy Fiber-Granule Cell Relay Invokes Postsynaptic Second-Messenger Regulation of Kv4 Channels. J Neurosci. 2016;36:11196-11207 pubmed

Zhang L, Wang X, Cao H, Chen Y, Chen X, Zhao X, et al. Vasopressin V1A receptor mediates cell proliferation through GRK2-EGFR-ERK1/2 pathway in A7r5 cells. Eur J Pharmacol. 2016;792:15-25 pubmed publisher

Gao J, Bai T, Ren L, Ding Y, Zhong X, Wang H, et al. The PLC/PKC/Ras/MEK/Kv channel pathway is involved in uncarboxylated osteocalcin-regulated insulin secretion in rats. Peptides. 2016;86:72-79 pubmed publisher

Sasaki T, Inami K, Numata Y, Funakoshi K, Yoshida M, Kumagai T, et al. Activation of p38 Mitogen-Activated Protein Kinase by Clotrimazole Induces Multidrug Resistance-Associated Protein 3 Activation through a Novel Transcriptional Element. J Pharmacol Exp Ther. 2016;359:102-9 pubmed publisher

Bruns B, Hönle T, Kellermann P, Ayala A, Perl M. Divergent Effects of Neutrophils on Fas-Induced Pulmonary Inflammation, Apoptosis, and Lung Damage. Shock. 2017;47:225-235 pubmed publisher

Ebenezer A, Arunachalam P, Elden B. H4R activation utilizes distinct signaling pathways for the production of RANTES and IL-13 in human mast cells. J Recept Signal Transduct Res. 2017;37:133-140 pubmed publisher

Maugeri G, D Amico A, Reitano R, Magro G, Cavallaro S, Salomone S, et al. PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression. Front Pharmacol. 2016;7:139 pubmed publisher

Chen S, Zhang L, Xu R, Ti Y, Zhao Y, Zhou L, et al. TheBDKRB2 +9/-9 Polymorphisms Influence Pro-Inflammatory Cytokine Levels in Knee Osteoarthritis by Altering TLR-2 Expression: Clinical and in Vitro Studies. Cell Physiol Biochem. 2016;38:1245-56 pubmed publisher

Cannavo A, Liccardo D, Eguchi A, Elliott K, Traynham C, Ibetti J, et al. Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun. 2016;7:10877 pubmed publisher

Wan J, Wu W, Chen Y, Kang N, Zhang R. Insufficient radiofrequency ablation promotes the growth of non-small cell lung cancer cells through PI3K/Akt/HIF-1α signals. Acta Biochim Biophys Sin (Shanghai). 2016;48:371-7 pubmed publisher

Teng J, Wu S, Chen J, Li Q, Peng F, Zhu Z, et al. The Activation of ERK1/2 and JNK MAPK Signaling by Insulin/IGF-1 Is Responsible for the Development of Colon Cancer with Type 2 Diabetes Mellitus. PLoS ONE. 2016;11:e0149822 pubmed publisher

Hu Y, Hou Z, Liu D, Yang X. Tartary buckwheat flavonoids protect hepatic cells against high glucose-induced oxidative stress and insulin resistance via MAPK signaling pathways. Food Funct. 2016;7:1523-36 pubmed publisher

Lee J, Paik J, Yun M, Lee S, Yang S. The Effect of (-)-Epigallocatechin-3-Gallate on IL-1β Induced IL-8 Expression in Orbital Fibroblast from Patients with Thyroid-Associated Ophthalmopathy. PLoS ONE. 2016;11:e0148645 pubmed publisher

Veena M, Melvin P, Prabhu S, Shailasree S, Shetty H, Kini K. Molecular cloning of a coiled-coil-nucleotide-binding-site-leucine-rich repeat gene from pearl millet and its expression pattern in response to the downy mildew pathogen. Mol Biol Rep. 2016;43:117-28 pubmed publisher

Jin C, Li J, Cheng L, Liu F, Wu N. Gp120 binding with DC-SIGN induces reactivation of HIV-1 provirus via the NF-κB signaling pathway. Acta Biochim Biophys Sin (Shanghai). 2016;48:275-81 pubmed publisher

Song N, Liu H, Ma X, Zhang S. Placental Growth Factor Promotes Ovarian Cancer Cell Invasion via ZEB2. Cell Physiol Biochem. 2016;38:351-8 pubmed publisher

Kim H, Yang J, Yoon S. Brief low [Mg(2+)]o-induced Ca(2+) spikes inhibit subsequent prolonged exposure-induced excitotoxicity in cultured rat hippocampal neurons. Korean J Physiol Pharmacol. 2016;20:101-9 pubmed publisher

de Oliveira A, Yousif N, Bhatia H, Hermanek J, Huell M, Fiebich B. Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia. J Neuroinflammation. 2016;13:11 pubmed publisher

Bae J, Han M, Yao C, Chung J. Chaetocin inhibits IBMX-induced melanogenesis in B16F10 mouse melanoma cells through activation of ERK. Chem Biol Interact. 2016;245:66-71 pubmed publisher

Yang S, Krug S, Heitmann J, Hu L, Reinhold A, Sauer S, et al. Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183-triggered opening of the blood-nerve barrier. Biomaterials. 2016;82:20-33 pubmed publisher

Liu J, Liu X, Liu Y, Sun Y, Li S, Li C, et al. MicroRNA 28-5p regulates ATP-binding cassette transporter A1 via inhibiting extracellular signal-regulated kinase 2. Mol Med Rep. 2016;13:433-40 pubmed publisher

Yang J, Hou Y, Zhou M, Wen S, Zhou J, Xu L, et al. Twist induces epithelial-mesenchymal transition and cell motility in breast cancer via ITGB1-FAK/ILK signaling axis and its associated downstream network. Int J Biochem Cell Biol. 2016;71:62-71 pubmed publisher

Han B, Zhou H, Jia G, Wang Y, Song Z, Wang G, et al. MAPKs and Hsc70 are critical to the protective effect of molecular hydrogen during the early phase of acute pancreatitis. FEBS J. 2016;283:738-56 pubmed publisher

He J, Johnson J, Monfregola J, Ramadass M, Pestonjamasp K, Napolitano G, et al. Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses. Mol Biol Cell. 2016;27:572-87 pubmed publisher

Lin L, Qiu Q, Zhou N, Dong W, Shen J, Jiang W, et al. Dickkopf-1 is involved in BMP9-induced osteoblast differentiation of C3H10T1/2 mesenchymal stem cells. BMB Rep. 2016;49:179-84 pubmed

Peng B, Zhu H, Klausen C, Ma L, Wang Y, Leung P. GnRH regulates trophoblast invasion via RUNX2-mediated MMP2/9 expression. Mol Hum Reprod. 2016;22:119-29 pubmed publisher

Adamopoulos C, Piperi C, Gargalionis A, Dalagiorgou G, Spilioti E, Korkolopoulou P, et al. Advanced glycation end products upregulate lysyl oxidase and endothelin-1 in human aortic endothelial cells via parallel activation of ERK1/2-NF-κB and JNK-AP-1 signaling pathways. Cell Mol Life Sci. 2016;73:1685-98 pubmed publisher

Rawendra R, Lin P, Chang C, Hsu J, Huang T, Shih W. Potentiation of Acute Promyelocytic Leukemia Cell Differentiation and Prevention of Leukemia Development in Mice by Oleanolic Acid. Anticancer Res. 2015;35:6583-90 pubmed

Gao Y, Liao G, Xiang C, Yang X, Cheng X, Ou Y. Effects of phycocyanin on INS-1 pancreatic β-cell mediated by PI3K/Akt/FoxO1 signaling pathway. Int J Biol Macromol. 2016;83:185-94 pubmed publisher

Na Y, Jung D, Gu G, Jang A, Suh Y, Seok S. The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production. Sci Signal. 2015;8:ra121 pubmed publisher

Park S, Lee J, Ku S, Cho I, Byun S, Kim S, et al. Isoliquiritigenin in licorice functions as a hepatic protectant by induction of antioxidant genes through extracellular signal-regulated kinase-mediated NF-E2-related factor-2 signaling pathway. Eur J Nutr. 2016;55:2431-2444 pubmed

Paeschke A, Possehl A, Klingel K, Voss M, Voss K, Kespohl M, et al. The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3. Eur J Immunol. 2016;46:619-33 pubmed publisher

Liao F, Zheng Y, Cai J, Fan J, Wang J, Yang J, et al. Catestatin attenuates endoplasmic reticulum induced cell apoptosis by activation type 2 muscarinic acetylcholine receptor in cardiac ischemia/reperfusion. Sci Rep. 2015;5:16590 pubmed publisher

Lieske N, Tonby K, Kvale D, Dyrhol Riise A, Tasken K. Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors. PLoS ONE. 2015;10:e0141903 pubmed publisher

Ito K, Matsuzaki M, Sasahara T, Shin M, Yayama K. Orthovanadate-Induced Vasoconstriction of Rat Mesenteric Arteries Is Mediated by Rho Kinase-Dependent Inhibition of Myosin Light Chain Phosphatase. Biol Pharm Bull. 2015;38:1809-16 pubmed publisher

Ali M, Driscoll C, Walters P, Limper A, Carmona E. β-Glucan-Activated Human B Lymphocytes Participate in Innate Immune Responses by Releasing Proinflammatory Cytokines and Stimulating Neutrophil Chemotaxis. J Immunol. 2015;195:5318-26 pubmed publisher

Nagaoka A, Yoshida H, Nakamura S, Morikawa T, Kawabata K, Kobayashi M, et al. Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID (Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199) and HA Synthases in Growth Factor-stimulated Fibroblasts. J Biol Chem. 2015;290:30910-23 pubmed publisher

Dong Z, Chen J, Ruan Y, Zhou T, Chen Y, Chen Y, et al. CFTR-regulated MAPK/NF-κB signaling in pulmonary inflammation in thermal inhalation injury. Sci Rep. 2015;5:15946 pubmed publisher

Castellana B, Aasen T, Moreno Bueno G, Dunn S, Ramón y Cajal S. Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells. Oncotarget. 2015;6:38239-56 pubmed publisher

Quatrini L, Molfetta R, Zitti B, Peruzzi G, Fionda C, Capuano C, et al. Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells. Sci Signal. 2015;8:ra108 pubmed publisher

Turrà D, El Ghalid M, Rossi F, Di Pietro A. Fungal pathogen uses sex pheromone receptor for chemotropic sensing of host plant signals. Nature. 2015;527:521-4 pubmed publisher

Fang F, Guo H, Zhang J, Ban L, Liu J, Yu P. Anti-cancer effects of 2-oxoquinoline derivatives on the HCT116 and LoVo human colon cancer cell lines. Mol Med Rep. 2015;12:8062-70 pubmed publisher

Xing R, Yang L, Jin Y, Sun L, Li C, Li Z, et al. Interleukin-21 Induces Proliferation and Proinflammatory Cytokine Profile of Fibroblast-like Synoviocytes of Patients with Rheumatoid Arthritis. Scand J Immunol. 2016;83:64-71 pubmed publisher

Piao C, Ralay Ranaivo H, Rusie A, Wadhwani N, Koh S, Wainwright M. Thrombin decreases expression of the glutamate transporter GLAST and inhibits glutamate uptake in primary cortical astrocytes via the Rho kinase pathway. Exp Neurol. 2015;273:288-300 pubmed publisher

Du L, Yang Y, Wang Y, Xue C, Kurihara H, Takahashi K. EPA-enriched phospholipids ameliorate cancer-associated cachexia mainly via inhibiting lipolysis. Food Funct. 2015;6:3652-62 pubmed publisher

Cao R, Wu W, Zhou X, Liu K, Li B, Huang X, et al. Let-7g induces granulosa cell apoptosis by targeting MAP3K1 in the porcine ovary. Int J Biochem Cell Biol. 2015;68:148-57 pubmed publisher

Wang D, Fu L, Sun H, Guo L, DuBois R. Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice. Gastroenterology. 2015;149:1884-1895.e4 pubmed publisher

Zhang X, Han X, Tang Y, Wu Y, Qu B, Shen N. miR-744 enhances type I interferon signaling pathway by targeting PTP1B in primary human renal mesangial cells. Sci Rep. 2015;5:12987 pubmed publisher

Xiong W, Shao Z, Xiong Y, Chen J, Sun Y, Zhu L, et al. Dehydroandrographolide enhances innate immunity of intestinal tract through up-regulation the expression of hBD-2. Daru. 2015;23:37 pubmed publisher

Zeng X, Li N, Pan D, Miao Q, Ma G, Liu Y, et al. Kruppel-like factor 2 inhibit the angiogenesis of cultured human liver sinusoidal endothelial cells through the ERK1/2 signaling pathway. Biochem Biophys Res Commun. 2015;464:1241-1247 pubmed publisher

Lin H, Lin H, Lin I, Chiou Y, Chen H, Liu C, et al. Mechanical phenotype of cancer cells: cell softening and loss of stiffness sensing. Oncotarget. 2015;6:20946-58 pubmed

Kondo H, Miyoshi K, Sakiyama S, Tangoku A, Noma T. Differential Regulation of Gene Expression of Alveolar Epithelial Cell Markers in Human Lung Adenocarcinoma-Derived A549 Clones. Stem Cells Int. 2015;2015:165867 pubmed publisher

Schlich R, Lamers D, Eckel J, Sell H. Adipokines enhance oleic acid-induced proliferation of vascular smooth muscle cells by inducing CD36 expression. Arch Physiol Biochem. 2015;121:81-7 pubmed publisher

Kippenberger S, Zöller N, Kleemann J, Müller J, Kaufmann R, Hofmann M, et al. STAT6-Dependent Collagen Synthesis in Human Fibroblasts Is Induced by Bovine Milk. PLoS ONE. 2015;10:e0131783 pubmed publisher

Li Y, Liu G, Li H, Bi Y. Neuregulin-1β Regulates the migration of Different Neurochemical Phenotypic Neurons from Organotypically Cultured Dorsal Root Ganglion Explants. Cell Mol Neurobiol. 2016;36:69-81 pubmed publisher

He M, Zheng B, Zhang Y, Zhang X, Wang C, Yang Z, et al. KLF4 mediates the link between TGF-β1-induced gene transcription and H3 acetylation in vascular smooth muscle cells. FASEB J. 2015;29:4059-70 pubmed publisher

Nimlamool W, Andrews R, Falk M. Connexin43 phosphorylation by PKC and MAPK signals VEGF-mediated gap junction internalization. Mol Biol Cell. 2015;26:2755-68 pubmed publisher

He J, Shen N, Huang X. Thyroid carcinoma cells produce PLGF to enhance metastasis. Tumour Biol. 2015;36:8601-7 pubmed publisher

Moriwaki Y, Takada K, Tsuji S, Kawashima K, Misawa H. Transcriptional regulation of SLURP2, a psoriasis-associated gene, is under control of IL-22 in the skin: A special reference to the nested gene LYNX1. Int Immunopharmacol. 2015;29:71-5 pubmed publisher

Franz D, Contreras F, González H, Prado C, Elgueta D, Figueroa C, et al. Dopamine receptors D3 and D5 regulate CD4(+)T-cell activation and differentiation by modulating ERK activation and cAMP production. J Neuroimmunol. 2015;284:18-29 pubmed publisher

Chen H, Shi B, Feng X, Kong W, Chen W, Geng L, et al. Leptin and Neutrophil-Activating Peptide 2 Promote Mesenchymal Stem Cell Senescence Through Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway in Patients With Systemic Lupus Erythematosus. Arthritis Rheumatol. 2015;67:2383-93 pubmed publisher

Liu S, Zhang X, Han N, Lv S, Xiong J. Pretreatment with low dose etomidate prevents etomidate-induced rat adrenal insufficiency by regulating oxidative stress-related MAPKs and apoptosis. Environ Toxicol Pharmacol. 2015;39:1212-20 pubmed publisher

Schweitzer K, Chen S, Law S, Van Demark M, Poirier C, Justice M, et al. Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures. Am J Physiol Lung Cell Mol Physiol. 2015;309:L175-87 pubmed publisher

Yuan Z, Guo W, Yang J, Li L, Wang M, Lei Y, et al. PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells. J Biol Chem. 2015;290:14927-44 pubmed publisher

Tan Y, Wang Y, Li L, Xia J, Peng S, He Y. Chemokine-like factor 1-derived C-terminal peptides induce the proliferation of dermal microvascular endothelial cells in psoriasis. PLoS ONE. 2015;10:e0125073 pubmed publisher

Bian Y, Ren L, Wang L, Xu S, Tao J, Zhang X, et al. A novel imidazopyridine derivative, X22, prevents the retinal ischemia-reperfusion injury via inhibition of MAPKs. Exp Eye Res. 2015;135:26-36 pubmed publisher

Jiang X, Guo C, Zeng X, Li H, Chen B, DU F. A soluble receptor for advanced glycation end-products inhibits myocardial apoptosis induced by ischemia/reperfusion via the JAK2/STAT3 pathway. Apoptosis. 2015;20:1033-47 pubmed publisher

Ramírez D, Saba J, Carniglia L, Durand D, Lasaga M, Caruso C. Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus. Mol Cell Endocrinol. 2015;411:28-37 pubmed publisher

Ali A, Mundi M, Koutsari C, Bernlohr D, Jensen M. Adipose Tissue Free Fatty Acid Storage In Vivo: Effects of Insulin Versus Niacin as a Control for Suppression of Lipolysis. Diabetes. 2015;64:2828-35 pubmed publisher

Cui T, Srivastava A, Han C, Yang L, Zhao R, Zou N, et al. XPC inhibits NSCLC cell proliferation and migration by enhancing E-Cadherin expression. Oncotarget. 2015;6:10060-72 pubmed

Jeon Y, Ahn Y, Chung W, Choi H, Suh Y. Synergistic effect between celecoxib and luteolin is dependent on estrogen receptor in human breast cancer cells. Tumour Biol. 2015;36:6349-59 pubmed publisher

Du L, Feng S, Yin L, Wang X, Zhang A, Yang K, et al. Identification and functional characterization of grass carp IL-17A/F1: An evaluation of the immunoregulatory role of teleost IL-17A/F1. Dev Comp Immunol. 2015;51:202-11 pubmed publisher

Qian Y, Shi D, Qiu J, Zhu F, Qian J, He S, et al. ObRb downregulation increases breast cancer cell sensitivity to tamoxifen. Tumour Biol. 2015;36:6813-21 pubmed publisher

Meka D, Müller Rischart A, Nidadavolu P, Mohammadi B, Motori E, Ponna S, et al. Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration. J Clin Invest. 2015;125:1873-85 pubmed publisher

Dembitz V, Lalić H, Ostojic A, Vrhovac R, Banfic H, Visnjic D. The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation. Int J Hematol. 2015;102:12-24 pubmed publisher

Wang J, Xu H, Wang Q, Zhang H, Lin Y, Zhang H, et al. CIAPIN1 targets Na⁺/H⁺ exchanger 1 to mediate MDA-MB-231 cells' metastasis through regulation of MMPs via ERK1/2 signaling pathway. Exp Cell Res. 2015;333:60-72 pubmed publisher

Drasin D, Guarnieri A, Neelakantan D, Kim J, Cabrera J, Wang C, et al. TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation. Cancer Res. 2015;75:1908-21 pubmed publisher

Chen B, Miller A, Rebelatto M, Brewah Y, Rowe D, Clarke L, et al. S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo. PLoS ONE. 2015;10:e0115828 pubmed publisher

Huang W, Zhu S, Liu Q, Li C, Li L. Placenta growth factor promotes migration through regulating epithelial-mesenchymal transition-related protein expression in cervical cancer. Int J Clin Exp Pathol. 2014;7:8506-19 pubmed

Iwao T, Kodama N, Kondo Y, Kabeya T, Nakamura K, Horikawa T, et al. Generation of enterocyte-like cells with pharmacokinetic functions from human induced pluripotent stem cells using small-molecule compounds. Drug Metab Dispos. 2015;43:603-10 pubmed publisher

Wang D, Han S, Peng R, Wang X, Yang X, Yang R, et al. FAM83D activates the MEK/ERK signaling pathway and promotes cell proliferation in hepatocellular carcinoma. Biochem Biophys Res Commun. 2015;458:313-20 pubmed publisher

Hebel T, Eisinger K, Neumeier M, Rein Fischboeck L, Pohl R, Meier E, et al. Lipid abnormalities in alpha/beta2-syntrophin null mice are independent from ABCA1. Biochim Biophys Acta. 2015;1851:527-36 pubmed publisher

Sun K, Zhang Y, Bogdanov M, Wu H, Song A, Li J, et al. Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity. Blood. 2015;125:1643-52 pubmed publisher

Gu X, Fu J, Bai J, Zhang C, Wang J, Pan W. Low-frequency electrical stimulation induces the proliferation and differentiation of peripheral blood stem cells into Schwann cells. Am J Med Sci. 2015;349:157-61 pubmed publisher

Bąbolewska E, Brzezińska Błaszczyk E. Human-derived cathelicidin LL-37 directly activates mast cells to proinflammatory mediator synthesis and migratory response. Cell Immunol. 2015;293:67-73 pubmed publisher

Wang J, Wu Y, Zhao F, Wu Y, Dong W, Zhao J, et al. Fgf-signaling-dependent Sox9a and Atoh1a regulate otic neural development in zebrafish. J Neurosci. 2015;35:234-44 pubmed publisher

Tamminen J, Yin M, Rönty M, Sutinen E, Pasternack A, Ritvos O, et al. Overexpression of activin-A and -B in malignant mesothelioma - attenuated Smad3 signaling responses and ERK activation promote cell migration and invasive growth. Exp Cell Res. 2015;332:102-15 pubmed publisher

Liu M, Yang J, Xing X, Cui X, Li M. Interleukin-17A promotes functional activation of systemic sclerosis patient-derived dermal vascular smooth muscle cells by extracellular-regulated protein kinases signalling pathway. Arthritis Res Ther. 2014;16:4223 pubmed publisher

Park H, Bolton E. Glial cell line-derived neurotrophic factor induces cell proliferation in the mouse urogenital sinus. Mol Endocrinol. 2015;29:289-306 pubmed publisher

Wang Z, Wang Y, Ye J, Lu X, Cheng Y, Xiang L, et al. bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway. J Cell Mol Med. 2015;19:595-607 pubmed publisher

Shan J, Donelan W, Hayner J, Zhang F, Dudenhausen E, Kilberg M. MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells. Biochim Biophys Acta. 2015;1853:539-48 pubmed publisher

Luo X, Li T, Zhu Y, Dai Y, Zhao J, Guo Z, et al. The insulinotrophic effect of insulin-like peptide 5 in vitro and in vivo. Biochem J. 2015;466:467-73 pubmed publisher

Friedrich M, Diegelmann J, Schauber J, Auernhammer C, Brand S. Intestinal neuroendocrine cells and goblet cells are mediators of IL-17A-amplified epithelial IL-17C production in human inflammatory bowel disease. Mucosal Immunol. 2015;8:943-58 pubmed publisher

Thaler R, Sturmlechner I, Spitzer S, Riester S, Rumpler M, Zwerina J, et al. Acute-phase protein serum amyloid A3 is a novel paracrine coupling factor that controls bone homeostasis. FASEB J. 2015;29:1344-59 pubmed publisher

Zhang R, Liu S, Guo B, Chang L, Li Y. Chemerin induces insulin resistance in rat cardiomyocytes in part through the ERK1/2 signaling pathway. Pharmacology. 2014;94:259-64 pubmed publisher

Cai H, Liu W, Xue Y, Shang X, Liu J, Li Z, et al. Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression. J Neuropathol Exp Neurol. 2015;74:25-37 pubmed publisher

Lee J, Patel K, Tae H, Lustig A, Kim J, Mattson M, et al. Ghrelin augments murine T-cell proliferation by activation of the phosphatidylinositol-3-kinase, extracellular signal-regulated kinase and protein kinase C signaling pathways. FEBS Lett. 2014;588:4708-19 pubmed publisher

Atif S, Lee S, Li L, Uematsu S, Akira S, Gorjestani S, et al. Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9. Eur J Immunol. 2015;45:513-24 pubmed publisher

Rath S, Das L, Kokate S, Pratheek B, Chattopadhyay S, Goswami C, et al. Regulation of Noxa-mediated apoptosis in Helicobacter pylori-infected gastric epithelial cells. FASEB J. 2015;29:796-806 pubmed publisher

Buendia I, Egea J, Parada E, Navarro E, Leon R, Rodríguez Franco M, et al. The melatonin-N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction. ACS Chem Neurosci. 2015;6:288-96 pubmed publisher

Goyal R, Goyal D, Chu N, Van Wickle J, Longo L. Cerebral artery alpha-1 AR subtypes: high altitude long-term acclimatization responses. PLoS ONE. 2014;9:e112784 pubmed publisher

Kim J, Yun J, Kim Y, Kwon E, Choi H, Yeom S, et al. Mutagenicity and tumor-promoting effects of Tiglium seed extract via PKC and MAPK signaling pathways. Biosci Biotechnol Biochem. 2015;79:374-83 pubmed publisher

Cheng D, Zhang L, Yang G, Zhao L, Peng F, Tian Y, et al. Hepatitis C virus NS5A drives a PTEN-PI3K/Akt feedback loop to support cell survival. Liver Int. 2015;35:1682-91 pubmed publisher

Akhtar N, Makki M, Haqqi T. MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes. Arthritis Rheumatol. 2015;67:423-34 pubmed publisher

Lisi S, Sisto M, D Amore M, Lofrumento D. Co-culture system of human salivary gland epithelial cells and immune cells from primary Sjögren's syndrome patients: an in vitro approach to study the effects of Rituximab on the activation of the Raf-1/ERK1/2 pathway. Int Immunol. 2015;27:183-94 pubmed publisher

Kao C, Chao A, Tsai C, Chuang W, Huang W, Chen G, et al. Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation. Cell Death Dis. 2014;5:e1510 pubmed publisher

Nowatari T, Murata S, Nakayama K, Sano N, Maruyama T, Nozaki R, et al. Sphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human. Hepatol Res. 2015;45:1136-45 pubmed publisher

Xing X, Gu X, Ma T, Ye H. Biglycan up-regulated vascular endothelial growth factor (VEGF) expression and promoted angiogenesis in colon cancer. Tumour Biol. 2015;36:1773-80 pubmed publisher

Gao X, Yu L, Moore A, Kissling G, Waalkes M, Dixon D. Cadmium and proliferation in human uterine leiomyoma cells: evidence of a role for EGFR/MAPK pathways but not classical estrogen receptor pathways. Environ Health Perspect. 2015;123:331-6 pubmed publisher

Lim H, Back K, Kim H, Choi Y, Park Y, Kook K. Hyaluronic acid induces COX-2 expression via CD44 in orbital fibroblasts from patients with thyroid-associated ophthalmopathy. Invest Ophthalmol Vis Sci. 2014;55:7441-50 pubmed publisher

Wang H, Liao S, Geng R, Zheng Y, Liao R, Yan F, et al. IGF-1 signaling via the PI3K/Akt pathway confers neuroprotection in human retinal pigment epithelial cells exposed to sodium nitroprusside insult. J Mol Neurosci. 2015;55:931-40 pubmed publisher

Raffo D, Pontiggia O, Bal de Kier Joffe E, Simian M. Non-genomic actions of estradiol and 4-OH-tamoxifen on murine breast cancer cells. Oncol Rep. 2015;33:439-47 pubmed publisher

Zhang K, Chen H, Chen Y, Qiu K, Zheng X, Li G, et al. Bisphenol A stimulates human lung cancer cell migration via upregulation of matrix metalloproteinases by GPER/EGFR/ERK1/2 signal pathway. Biomed Pharmacother. 2014;68:1037-43 pubmed publisher

Du X, Li Y, Jing X, Zhao L. Effect of a heat shock protein 90-specific inhibitor on the proliferation and apoptosis induced by VEGF-C in cervical cancer cells. Exp Ther Med. 2014;8:1559-1564 pubmed

Beermann S, Vauth M, Hein R, Seifert R, Neumann D. Distinct signalling pathways of murine histamine H1- and H4-receptors expressed at comparable levels in HEK293 cells. PLoS ONE. 2014;9:e107481 pubmed publisher

Xia Y, Khoi P, Yoon H, Lian S, Joo Y, Chay K, et al. Piperine inhibits IL-1β-induced IL-6 expression by suppressing p38 MAPK and STAT3 activation in gastric cancer cells. Mol Cell Biochem. 2015;398:147-56 pubmed publisher

Shu Q, Li W, Li J, Wang W, Liu C, Sun K. Cross-talk between cAMP and MAPK pathways in HSD11B2 induction by hCG in placental trophoblasts. PLoS ONE. 2014;9:e107938 pubmed publisher

Huang Y, Zhao M, Xu H, Wang K, Fu Z, Jiang Y, et al. RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis. Oncotarget. 2014;5:6734-45 pubmed

Liu J, He J, Huang L, Dou L, Wu S, Yuan Q. Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury and neurite outgrowth. Neural Regen Res. 2014;9:943-50 pubmed publisher

Nakamura M, Nakagawa M, Watanabe J. Ubiquitin-like protein MNSFβ negatively regulates T cell function and survival. Immunol Invest. 2015;44:1-12 pubmed publisher

Romero Ramirez H, Morales Guadarrama M, Pelayo R, López Santiago R, Santos Argumedo L. CD38 expression in early B-cell precursors contributes to extracellular signal-regulated kinase-mediated apoptosis. Immunology. 2015;144:271-81 pubmed publisher

Koivisto E, Jurado Acosta A, Moilanen A, Tokola H, Aro J, Pennanen H, et al. Characterization of the regulatory mechanisms of activating transcription factor 3 by hypertrophic stimuli in rat cardiomyocytes. PLoS ONE. 2014;9:e105168 pubmed publisher

Li J, Philip J, Xu X, Theccanat T, Abdur Razzaque M, Akhter S. β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling. J Mol Cell Cardiol. 2014;76:73-83 pubmed publisher

Zhong W, Hutchinson T, Chebolu S, Darmani N. Serotonin 5-HT3 receptor-mediated vomiting occurs via the activation of Ca2+/CaMKII-dependent ERK1/2 signaling in the least shrew (Cryptotis parva). PLoS ONE. 2014;9:e104718 pubmed publisher

Lu J, Zhu Y, Feng W, Pan Y, Li S, Han D, et al. Platelet-derived growth factor mediates interleukin-13-induced collagen I production in mouse airway fibroblasts. J Biosci. 2014;39:693-700 pubmed

Nakajima Y, Inagaki Y, Kido J, Nagata T. Advanced glycation end products increase expression of S100A8 and A9 via RAGE-MAPK in rat dental pulp cells. Oral Dis. 2015;21:328-34 pubmed publisher

Han S, Li Z, Master L, Master Z, Wu A. Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin ?1-ERK pathway. Br J Cancer. 2014;111:1400-9 pubmed publisher

Latvala S, Mäkelä S, Miettinen M, Charpentier E, Julkunen I. Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages. Clin Exp Immunol. 2014;178:320-33 pubmed publisher

Lim A, Chan L, Tang S, Lai K, Leung J. Albumin and glycated albumin activate KIM-1 release in tubular epithelial cells through distinct kinetics and mechanisms. Inflamm Res. 2014;63:831-9 pubmed publisher

Kim G, Lee S, Kim Y. Torilis japonica extract, a new potential EMT suppressor agent by regulation of EGFR signaling pathways. Int J Oncol. 2014;45:1673-9 pubmed publisher

Lin T, Lu C, Wang C, Huang S, Wang S. Cyclooxygenase 2 inhibitor celecoxib inhibits glutamate release by attenuating the PGE2/EP2 pathway in rat cerebral cortex endings. J Pharmacol Exp Ther. 2014;351:134-45 pubmed publisher

Poenitzsch Strong A, Setaluri V, Spiegelman V. MicroRNA-340 as a modulator of RAS-RAF-MAPK signaling in melanoma. Arch Biochem Biophys. 2014;563:118-24 pubmed publisher

Del Nogal M, Troyano N, Calleros L, Griera M, Rodriguez Puyol M, Rodriguez Puyol D, et al. Hyperosmolarity induced by high glucose promotes senescence in human glomerular mesangial cells. Int J Biochem Cell Biol. 2014;54:98-110 pubmed publisher

Clancy P, Koblar S, Golledge J. Angiotensin receptor 1 blockade reduces secretion of inflammation associated cytokines from cultured human carotid atheroma and vascular cells in association with reduced extracellular signal regulated kinase expression and activation. Atherosclerosis. 2014;236:108-15 pubmed publisher

Bąbolewska E, Pietrzak A, Brzezińska Błaszczyk E. Cathelicidin rCRAMP stimulates rat mast cells to generate cysteinyl leukotrienes, synthesize TNF and migrate: involvement of PLC/A2, PI3K and MAPK signaling pathways. Int Immunol. 2014;26:637-46 pubmed publisher

Otte A, Rauprich F, von der Ohe J, Hillemanns P, Hass R. Interference of Ca²? with the proliferation of SCCOHT-1 and ovarian adenocarcinoma cells. Int J Oncol. 2014;45:1151-8 pubmed publisher

Kim B, Kim H, Lee G, So I, Kim S. Effects of San-Huang-Xie-Xin-tang, a traditional Chinese prescription for clearing away heat and toxin, on the pacemaker activities of interstitial cells of Cajal from the murine small intestine. J Ethnopharmacol. 2014;155:744-52 pubmed publisher

Uekita T, Fujii S, Miyazawa Y, Iwakawa R, Narisawa Saito M, Nakashima K, et al. Oncogenic Ras/ERK signaling activates CDCP1 to promote tumor invasion and metastasis. Mol Cancer Res. 2014;12:1449-59 pubmed publisher

Lee Y, Park H, Woo S, Park E, Kang J. RhoA/phosphatidylinositol 3-kinase/protein kinase B/mitogen-activated protein kinase signaling after growth arrest-specific protein 6/mer receptor tyrosine kinase engagement promotes epithelial cell growth and wound repair via upregulation of hepatoc. J Pharmacol Exp Ther. 2014;350:563-77 pubmed publisher

Mao Y, Sarhan D, Steven A, Seliger B, Kiessling R, Lundqvist A. Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity. Clin Cancer Res. 2014;20:4096-106 pubmed publisher

Li H, Xu L, Li C, Zhao L, Ma Y, Zheng H, et al. Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells. Mol Cancer. 2014;13:136 pubmed publisher

Leite P, Lima Araújo K, França G, Lagrota Candido J, Santos W, Quirico Santos T. Implant of polymer containing pentacyclic triterpenes from Eugenia punicifolia inhibits inflammation and activates skeletal muscle remodeling. Arch Immunol Ther Exp (Warsz). 2014;62:483-91 pubmed publisher

Ito T, Morita T, Yoshida K, Negishi T, Yukawa K. Semaphorin 3A-Plexin-A1 signaling through ERK activation is crucial for Toll-like receptor-induced NO production in BV-2 microglial cells. Int J Mol Med. 2014;33:1635-42 pubmed publisher

Varela L, Bermudez B, Ortega Gomez A, Lopez S, Sanchez R, Villar J, et al. Postprandial triglyceride-rich lipoproteins promote invasion of human coronary artery smooth muscle cells in a fatty-acid manner through PI3k-Rac1-JNK signaling. Mol Nutr Food Res. 2014;58:1349-64 pubmed publisher

Sisto M, Lisi S, D Amore M, Lofrumento D. The metalloproteinase ADAM17 and the epidermal growth factor receptor (EGFR) signaling drive the inflammatory epithelial response in Sjögren's syndrome. Clin Exp Med. 2015;15:215-25 pubmed publisher

Tavares N, Araújo Santos T, Afonso L, Nogueira P, Lopes U, Soares R, et al. Understanding the mechanisms controlling Leishmania amazonensis infection in vitro: the role of LTB4 derived from human neutrophils. J Infect Dis. 2014;210:656-66 pubmed publisher

Terada N, Shiraishi T, Zeng Y, Aw Yong K, Mooney S, Liu Z, et al. Correlation of Sprouty1 and Jagged1 with aggressive prostate cancer cells with different sensitivities to androgen deprivation. J Cell Biochem. 2014;115:1505-15 pubmed publisher

Liu F, Liu X, Zhang L, Cheng Y, Jiang Y. Binding of prorenin to (pro)renin receptor induces the proliferation of human umbilical artery smooth muscle cells via ROS generation and ERK1/2 activation. J Renin Angiotensin Aldosterone Syst. 2014;15:99-108 pubmed publisher

Jin Y, Zhang W, Liu Y, Zhang M, Xu L, Wu Q, et al. rhPDGF-BB via ERK pathway osteogenesis and adipogenesis balancing in ADSCs for critical-sized calvarial defect repair. Tissue Eng Part A. 2014;20:3303-13 pubmed publisher

Wu K, Huang G, Chen C, Chang H, Deng Y. Cyclosporine A induces connective tissue growth factor expression in human gingival fibroblasts: suppression by epigallocatechin-3-gallate. J Formos Med Assoc. 2014;113:828-32 pubmed publisher

Osório C, Chacón P, White M, Kisiswa L, Wyatt S, Rodríguez Tébar A, et al. Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL. Mol Cell Neurosci. 2014;59:24-36 pubmed publisher

Stampolidis P, Ullrich A, Iacobelli S. LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention. Oncogene. 2015;34:39-52 pubmed publisher

Wang Y, Wang H, Hegde V, Dubuisson O, Gao Z, Dhurandhar N, et al. Interplay of pro- and anti-inflammatory cytokines to determine lipid accretion in adipocytes. Int J Obes (Lond). 2013;37:1490-8 pubmed publisher

Li Y, Li B, Wan X, Zhang W, Zhong L, Tang S. NMDA receptor activation stimulates transcription-independent rapid wnt5a protein synthesis via the MAPK signaling pathway. Mol Brain. 2012;5:1 pubmed publisher

Dellinger M, Brekken R. Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium. PLoS ONE. 2011;6:e28947 pubmed publisher

Milara J, Serrano A, Peiró T, Gavaldá A, Miralpeix M, Morcillo E, et al. Aclidinium inhibits human lung fibroblast to myofibroblast transition. Thorax. 2012;67:229-37 pubmed publisher

Glaros E, Kim W, Garner B. Myriocin-mediated up-regulation of hepatocyte apoA-I synthesis is associated with ERK inhibition. Clin Sci (Lond). 2010;118:727-36 pubmed publisher

Yan J, Gao Z, Yu G, He Q, Weng J, Ye J. Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha. Mol Endocrinol. 2007;21:1630-41 pubmed

Brown S, Szyf M. Epigenetic programming of the rRNA promoter by MBD3. Mol Cell Biol. 2007;27:4938-52 pubmed

Hamazaki T, Kehoe S, Nakano T, Terada N. The Grb2/Mek pathway represses Nanog in murine embryonic stem cells. Mol Cell Biol. 2006;26:7539-49 pubmed

Chen X, Mao Z, Liu S, Liu H, Wang X, Wu H, et al. Dedifferentiation of adult human myoblasts induced by ciliary neurotrophic factor in vitro. Mol Biol Cell. 2005;16:3140-51 pubmed

Pang L, Sawada T, Decker S, Saltiel A. Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J Biol Chem. 1995;270:13585-8 pubmed

Dudley D, Pang L, Decker S, Bridges A, Saltiel A. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A. 1995;92:7686-9 pubmed

Alessi D, Cuenda A, Cohen P, Dudley D, Saltiel A. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem. 1995;270:27489-94 pubmed