Yuan X, Wu Q, Wang P, Jing Y, Yao H, Tang Y, et al. Intraspinal administration of interleukin-7 promotes neuronal apoptosis and limits functional recovery through JAK/STAT5 pathway following spinal cord injury. Biochem Biophys Res Commun. 2019;514:1023-1029 pubmed publisher

Randlett O, Haesemeyer M, Forkin G, Shoenhard H, Schier A, Engert F, et al. Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish. Curr Biol. 2019;29:1337-1345.e4 pubmed publisher

Raimondi M, Cesselli D, Di Loreto C, La Marra F, Schneider C, Demarchi F. USP1 (ubiquitin specific peptidase 1) targets ULK1 and regulates its cellular compartmentalization and autophagy. Autophagy. 2019;15:613-630 pubmed publisher

Johnston A, Bu W, Hein S, Garcia S, Camacho L, Xue L, et al. Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions. Breast Cancer Res. 2018;20:42 pubmed publisher

Cant Barrett K, Spijkers Hagelstein J, Buijs Gladdines J, Uitdehaag J, Smits W, van der Zwet J, et al. MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia. Leukemia. 2016;30:1832-43 pubmed publisher

Panić G, Vargas M, Scandale I, Keiser J. Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni. PLoS Negl Trop Dis. 2015;9:e0003962 pubmed publisher

Liao Z, Gu L, Vergalli J, Mariani S, De Dominici M, Lokareddy R, et al. Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia. Mol Cancer Ther. 2015;14:1777-93 pubmed publisher

Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher

Nogami A, Oshikawa G, Okada K, Fukutake S, Umezawa Y, Nagao T, et al. FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia. Oncotarget. 2015;6:9189-205 pubmed

Borriello F, Longo M, Spinelli R, Pecoraro A, Granata F, Staiano R, et al. IL-3 synergises with basophil-derived IL-4 and IL-13 to promote the alternative activation of human monocytes. Eur J Immunol. 2015;45:2042-51 pubmed publisher

Enyeart J, Enyeart J. Adrenal fasciculata cells express T-type and rapidly and slowly activating L-type Ca2+ channels that regulate cortisol secretion. Am J Physiol Cell Physiol. 2015;308:C899-918 pubmed publisher

Kim H, Lee W, Lee K, Bae S, Kim M, Joo Y, et al. Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia. Ann Hematol. 2015;94:739-46 pubmed publisher

Hartmann F, Khademi M, Aram J, Ammann S, Kockum I, Constantinescu C, et al. Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells. Nat Commun. 2014;5:5056 pubmed publisher

Finlay Schultz J, Cittelly D, Hendricks P, Patel P, Kabos P, Jacobsen B, et al. Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a. Oncogene. 2015;34:3676-87 pubmed publisher

Sempio C, Morini L, Vignali C, Groppi A. Simple and sensitive screening and quantitative determination of 88 psychoactive drugs and their metabolites in blood through LC-MS/MS: application on postmortem samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;970:1-7 pubmed publisher

Li H, Zheng H, Sun Y, Yu Q, Li L. Signal transducer and activator of transcription 5a inhibited by pimozide may regulate survival of goat mammary gland epithelial cells by regulating parathyroid hormone-related protein. Gene. 2014;551:279-89 pubmed publisher

Ritorto M, Ewan R, Pérez Oliva A, Knebel A, Buhrlage S, Wightman M, et al. Screening of DUB activity and specificity by MALDI-TOF mass spectrometry. Nat Commun. 2014;5:4763 pubmed publisher

Sprissler C, Belenki D, Maurer H, Aumann K, Pfeifer D, Klein C, et al. Depletion of STAT5 blocks TEL-SYK-induced APMF-type leukemia with myelofibrosis and myelodysplasia in mice. Blood Cancer J. 2014;4:e240 pubmed publisher

Anwar Mohamed A, Barakat K, Bhat R, Noskov S, Tyrrell D, Tuszynski J, et al. A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity. Toxicol Lett. 2014;230:382-92 pubmed publisher

Trasi N, Baird J, Kestur U, Taylor L. Factors influencing crystal growth rates from undercooled liquids of pharmaceutical compounds. J Phys Chem B. 2014;118:9974-82 pubmed publisher

Duluc D, Joo H, Ni L, Yin W, Upchurch K, Li D, et al. Induction and activation of human Th17 by targeting antigens to dendritic cells via dectin-1. J Immunol. 2014;192:5776-88 pubmed publisher

Schafranek L, Nievergall E, Powell J, Hiwase D, Leclercq T, Hughes T, et al. Sustained inhibition of STAT5, but not JAK2, is essential for TKI-induced cell death in chronic myeloid leukemia. Leukemia. 2015;29:76-85 pubmed publisher

Liang Q, Dexheimer T, Zhang P, Rosenthal A, Villamil M, You C, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014;10:298-304 pubmed publisher

Mothi M, Sampson S. Pimozide for schizophrenia or related psychoses. Cochrane Database Syst Rev. 2013;:CD001949 pubmed publisher

Fabbro S, Aultman J, Mostow E. Delusions of parasitosis: ethical and clinical considerations. J Am Acad Dermatol. 2013;69:156-9 pubmed publisher

Gunduz Bruce H, Oliver S, Gueorguieva R, Forselius Bielen K, D Souza D, Zimolo Z, et al. Efficacy of pimozide augmentation for clozapine partial responders with schizophrenia. Schizophr Res. 2013;143:344-7 pubmed publisher

Rizzo R, Eddy C, Calì P, Gulisano M, Cavanna A. Metabolic effects of aripiprazole and pimozide in children with Tourette syndrome. Pediatr Neurol. 2012;47:419-22 pubmed publisher

Preskorn S. Changes in the product label for pimozide illustrate both the promises and the challenges of personalized medicine. J Clin Psychiatry. 2012;73:1191-3 pubmed publisher

Rogers H, Bhattaram A, Zineh I, Gobburu J, Mathis M, Laughren T, et al. CYP2D6 genotype information to guide pimozide treatment in adult and pediatric patients: basis for the U.S. Food and Drug Administration's new dosing recommendations. J Clin Psychiatry. 2012;73:1187-90 pubmed publisher

Covell D. Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen. PLoS ONE. 2012;7:e44631 pubmed publisher

Roessner V, Schoenefeld K, Buse J, Bender S, Ehrlich S, Munchau A. Pharmacological treatment of tic disorders and Tourette Syndrome. Neuropharmacology. 2013;68:143-9 pubmed publisher

Smyj R, Wang X, Han F. Pimozide. Profiles Drug Subst Excip Relat Methodol. 2012;37:287-311 pubmed publisher

Sharaf S. Effect of GnRHa, pimozide and Ovaprim on ovulation and plasma sex steroid hormones in African catfish Clarias gariepinus. Theriogenology. 2012;77:1709-16 pubmed publisher

Grosso S, Verrotti A, Messina M, Sacchini M, Balestri P. Management of status dystonicus in children. Cases report and review. Eur J Paediatr Neurol. 2012;16:390-5 pubmed publisher

Bar Natan M, Nelson E, Walker S, Kuang Y, Distel R, Frank D. Dual inhibition of Jak2 and STAT5 enhances killing of myeloproliferative neoplasia cells. Leukemia. 2012;26:1407-10 pubmed publisher

Chen J, Dexheimer T, Ai Y, Liang Q, Villamil M, Inglese J, et al. Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells. Chem Biol. 2011;18:1390-400 pubmed publisher

Collins L, Sager T, Sams A, Pennarola A, Port R, Shahriari M, et al. The novel adenosine A2A antagonist Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade. Pharmacol Biochem Behav. 2012;100:498-505 pubmed publisher

Agarwal M, Giannoni Guzmán M, Morales Matos C, Del Valle Díaz R, Abramson C, Giray T. Dopamine and octopamine influence avoidance learning of honey bees in a place preference assay. PLoS ONE. 2011;6:e25371 pubmed publisher

Zarazaga L, Celi I, Guzmán J, Malpaux B. The effect of nutrition on the neural mechanisms potentially involved in melatonin-stimulated LH secretion in female Mediterranean goats. J Endocrinol. 2011;211:263-72 pubmed publisher

Gulisano M, Calì P, Cavanna A, Eddy C, Rickards H, Rizzo R. Cardiovascular safety of aripiprazole and pimozide in young patients with Tourette syndrome. Neurol Sci. 2011;32:1213-7 pubmed publisher

Martin W, Forouzanfar T. The efficacy of anticonvulsants on orofacial pain: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111:627-33 pubmed publisher

Friedman J, Lindenmayer J, Alcantara F, Bowler S, Parak M, White L, et al. Pimozide augmentation of clozapine inpatients with schizophrenia and schizoaffective disorder unresponsive to clozapine monotherapy. Neuropsychopharmacology. 2011;36:1289-95 pubmed publisher

Yang M, Zhou M, He L, Chen N, Zakrzewska J. Non-antiepileptic drugs for trigeminal neuralgia. Cochrane Database Syst Rev. 2011;:CD004029 pubmed publisher

Nelson E, Walker S, Weisberg E, Bar Natan M, Barrett R, Gashin L, et al. The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors. Blood. 2011;117:3421-9 pubmed publisher

Schmalhofer W, Swensen A, Thomas B, Felix J, Haedo R, Solly K, et al. A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel. Assay Drug Dev Technol. 2010;8:714-26 pubmed publisher

Ladizinski B, Busse K, Bhutani T, Koo J. Aripiprazole as a viable alternative for treating delusions of parasitosis. J Drugs Dermatol. 2010;9:1531-2 pubmed

Guzmán J, Cal R, García López A, Chereguini O, Kight K, Olmedo M, et al. Effects of in vivo treatment with the dopamine antagonist pimozide and gonadotropin-releasing hormone agonist (GnRHa) on the reproductive axis of Senegalese sole (Solea senegalensis). Comp Biochem Physiol A Mol Integr Physiol. 2011;158:235-45 pubmed publisher

Gosai S, Kwak J, Luke C, Long O, King D, Kovatch K, et al. Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin ?1-antitrypsin Z. PLoS ONE. 2010;5:e15460 pubmed publisher

Bancila M, Copin J, Daali Y, Schatlo B, Gasche Y, Bijlenga P. Two structurally different T-type Ca 2+ channel inhibitors, mibefradil and pimozide, protect CA1 neurons from delayed death after global ischemia in rats. Fundam Clin Pharmacol. 2011;25:469-78 pubmed publisher

Reid E, Lio P. Successful treatment of Morgellons disease with pimozide therapy. Arch Dermatol. 2010;146:1191-3 pubmed publisher

Trudeau V, Somoza G, Natale G, Pauli B, Wignall J, Jackman P, et al. Hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin-releasing hormone agonist and a dopamine antagonist. Reprod Biol Endocrinol. 2010;8:36 pubmed publisher

Pringsheim T, Marras C. Pimozide for tics in Tourette's syndrome. Cochrane Database Syst Rev. 2009;:CD006996 pubmed publisher

Rathbone J, McMonagle T. Pimozide for schizophrenia or related psychoses. Cochrane Database Syst Rev. 2007;:CD001949 pubmed

Browne R, Li H, Seratt J, Kouba A. Progesterone improves the number and quality of hormone induced Fowler toad (Bufo fowleri) oocytes. Reprod Biol Endocrinol. 2006;4:3 pubmed

Lorenzo C, Koo J. Pimozide in dermatologic practice: a comprehensive review. Am J Clin Dermatol. 2004;5:339-49 pubmed

van Vloten W. Pimozide: use in dermatology. Dermatol Online J. 2003;9:3 pubmed

Sultana A, McMonagle T. Pimozide for schizophrenia or related psychoses. Cochrane Database Syst Rev. 2000;:CD001949 pubmed

Sultana A, McMonagle T. Pimozide for schizophrenia or related psychoses. Cochrane Database Syst Rev. 2000;:CD001949 pubmed

Tueth M, Cheong J. Clinical uses of pimozide. South Med J. 1993;86:344-9 pubmed

Colvin C, Tankanow R. Pimozide: use in Tourette's syndrome. Drug Intell Clin Pharm. 1985;19:421-4 pubmed

Shapiro A, Shapiro E, Fulop G. Pimozide treatment of tic and Tourette disorders. Pediatrics. 1987;79:1032-9 pubmed

Opler L, Feinberg S. The role of pimozide in clinical psychiatry: a review. J Clin Psychiatry. 1991;52:221-33 pubmed