This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Pentoxifylline
catalog :
P1784
citations: 61
Reference
Lai J, Svedin P, Ek C, Mottahedin A, Wang X, Levy O, et al. Vancomycin Is Protective in a Neonatal Mouse Model of Staphylococcus epidermidis-Potentiated Hypoxic-Ischemic Brain Injury. Antimicrob Agents Chemother. 2020;64: pubmed publisher
Tsunoda R, Serrano Recalde E, Arruda R, Oliveira B, Pinto S, Celeghini E. Effects of pentoxifylline supplementation to semen extender on post-breeding inflammation response assessed by endometrial cytology and vascular perfusion in mares. Anim Reprod Sci. 2019;208:106128 pubmed publisher
Tian L, Ye Z, Kafka K, Stewart D, Anders R, Schwarz K, et al. Biliary Atresia Relevant Human Induced Pluripotent Stem Cells Recapitulate Key Disease Features in a Dish. J Pediatr Gastroenterol Nutr. 2019;68:56-63 pubmed publisher
Salian S, Nayak G, Kumari S, Patel S, Gowda S, Shenoy Y, et al. Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development. J Assist Reprod Genet. 2019;36:255-266 pubmed publisher
Fernández Zafra T, Gao T, Jurczak A, Sandor K, Hore Z, Agalave N, et al. Exploring the transcriptome of resident spinal microglia after collagen antibody-induced arthritis. Pain. 2019;160:224-236 pubmed publisher
Talar B, Gajos Michniewicz A, Talar M, Chouaib S, Czyz M. Pentoxifylline Inhibits WNT Signalling in ?-Cateninhigh Patient-Derived Melanoma Cell Populations. PLoS ONE. 2016;11:e0158275 pubmed publisher
Gonzalez Fajardo L, Fernández O, MCMAHON PRATT D, Saravia N. Ex vivo host and parasite response to antileishmanial drugs and immunomodulators. PLoS Negl Trop Dis. 2015;9:e0003820 pubmed publisher
Wang X, Parrish A. Loss of α(E)-catenin promotes Fas mediated apoptosis in tubular epithelial cells. Apoptosis. 2015;20:921-9 pubmed publisher
De Oliveira A, Poça K, Totino P, Paumgartten F. Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship. PLoS ONE. 2015;10:e0117842 pubmed publisher
Johnson D, Pascoe E, Badve S, Dalziel K, Cass A, Clarke P, et al. A randomized, placebo-controlled trial of pentoxifylline on erythropoiesis-stimulating agent hyporesponsiveness in anemic patients with CKD: the Handling Erythropoietin Resistance With Oxpentifylline (HERO) trial. Am J Kidney Dis. 2015;65:49-57 pubmed publisher
Mathurin P, Louvet A, Duhamel A, Nahon P, Carbonell N, Boursier J, et al. Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. JAMA. 2013;310:1033-41 pubmed publisher
Halegoua De Marzio D, Fenkel J. Treatment of severe alcoholic hepatitis with corticosteroids and pentoxifylline. JAMA. 2013;310:1029-30 pubmed publisher
Ciociola F, Colpi G. Peyronie's disease: a "triple oxygenant therapy". Arch Ital Urol Androl. 2013;85:36-40 pubmed publisher
Aljudaibi B, Qumosani K, Chandok N. Pentoxifylline for slow to resolve hepatopulmonary syndrome post liver transplantation: helpful or unnecessary?. Acta Gastroenterol Belg. 2013;76:70-1 pubmed
Parker R, Armstrong M, Corbett C, Rowe I, Houlihan D. Systematic review: pentoxifylline for the treatment of severe alcoholic hepatitis. Aliment Pharmacol Ther. 2013;37:845-54 pubmed publisher
Godlevsky L, Drozdova G, Kobolev E, Mustyatsa V, Polyasnyi V. Pentoxifylline potentiates antiepileptic activity of diazepam on the model of treatment-resistant focal epilepsy. Bull Exp Biol Med. 2013;154:326-8 pubmed
Baykara M, Atabek M, Eklioğlu B, Kurtoglu S. Pentoxifylline treatment for protecting diabetic retinopaty in children with type 1 diabetes. J Pediatr Endocrinol Metab. 2013;26:19-24 pubmed publisher
Bravo Cuellar A, Hernandez Flores G, Lerma Díaz J, Domínguez Rodríguez J, Jave Suarez L, de Celis Carrillo R, et al. Pentoxifylline and the proteasome inhibitor MG132 induce apoptosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65. J Biomed Sci. 2013;20:13 pubmed publisher
Fugler L, Eades S, Moore R, Koch C, Keowen M. Plasma matrix metalloproteinase activity in horses after intravenous infusion of lipopolysaccharide and treatment with matrix metalloproteinase inhibitors. Am J Vet Res. 2013;74:473-80 pubmed publisher
Nisi A, Panfili M, De Rosa G, Boffa G, Groppa F, Gusella M, et al. Pharmacokinetics of pentoxifylline and its main metabolites in patients with different degrees of heart failure following a single dose of a modified-release formulation. J Clin Pharmacol. 2013;53:51-7 pubmed publisher
Badri S, Dashti Khavidaki S, Ahmadi F, Mahdavi Mazdeh M, Abbasi M, Khalili H. Effect of add-on pentoxifylline on proteinuria in membranous glomerulonephritis: a 6-month placebo-controlled trial. Clin Drug Investig. 2013;33:215-22 pubmed publisher
Chukanova E, Khodzhamzharov B, Chukanova A. [Current possibilities of the correction of oxidative stress in acute brain ischaemia]. Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112:79-82 pubmed
Akudugu J, Serafin A, Böhm L. In vitro radiosensitization by pentoxifylline does not depend on p53 status. Int J Radiat Biol. 2013;89:462-70 pubmed publisher
Potts J, Verma S. Alcoholic hepatitis: diagnosis and management in 2012. Expert Rev Gastroenterol Hepatol. 2012;6:695-710 pubmed publisher
Jull A, Arroll B, Parag V, Waters J. Pentoxifylline for treating venous leg ulcers. Cochrane Database Syst Rev. 2012;12:CD001733 pubmed publisher
Gamidov C, Ovchinnikov R, Popova A, Tkhagapsoeva R, Izhbaev S. [Current approach to therapy for male infertility in patients with varicocele]. Ter Arkh. 2012;84:56-61 pubmed
Stepanovs D, Mishnev A. Multicomponent pharmaceutical cocrystals: furosemide and pentoxifylline. Acta Crystallogr C. 2012;68:o488-91 pubmed publisher
Babaei S, Bayat M, Nouruzian M, Bayat M. Pentoxifylline improves cutaneous wound healing in streptozotocin-induced diabetic rats. Eur J Pharmacol. 2013;700:165-72 pubmed publisher
Norsted Gregory E, Delaney A, Abdelmoaty S, Bas D, Codeluppi S, Wigerblad G, et al. Pentoxifylline and propentofylline prevent proliferation and activation of the mammalian target of rapamycin and mitogen activated protein kinase in cultured spinal astrocytes. J Neurosci Res. 2013;91:300-12 pubmed publisher
Nasiri Toosi Z, Dashti Khavidaki S, Khalili H, Lessan Pezeshki M. A review of the potential protective effects of pentoxifylline against drug-induced nephrotoxicity. Eur J Clin Pharmacol. 2013;69:1057-73 pubmed publisher
Sohail U, Satapathy S. Diagnosis and management of alcoholic hepatitis. Clin Liver Dis. 2012;16:717-36 pubmed publisher
Kamran M, Gude R. Preclinical evaluation of the antimetastatic efficacy of Pentoxifylline on A375 human melanoma cell line. Biomed Pharmacother. 2012;66:617-26 pubmed publisher
Türke B, Balázs C. [Treatment of pretibial myxoedema with pentoxifylline]. Orv Hetil. 2012;153:1719-22 pubmed publisher
Spriggs M, Reeder C. Treatment of vasculitis and dermatitis in a 59-yr-old Nile hippopotamus (Hippopotamus amphibius). J Zoo Wildl Med. 2012;43:652-6 pubmed
Gupta V. Chemical stability of pentoxifylline in a topical cream. Int J Pharm Compd. 2012;16:80-1 pubmed
Stevens J, Simpson E, Harnan S, Squires H, Meng Y, Thomas S, et al. Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. Br J Surg. 2012;99:1630-8 pubmed publisher
Sidhu S, Goyal O, Singla M, Bhatia K, Chhina R, Sood A. Pentoxifylline in severe alcoholic hepatitis: a prospective, randomised trial. J Assoc Physicians India. 2012;60:20-2 pubmed
Fang C, Huang J, Shyu R, Yen C, Shiao C, Chiang C, et al. Fibrin-Induced epithelial-to-mesenchymal transition of peritoneal mesothelial cells as a mechanism of peritoneal fibrosis: effects of pentoxifylline. PLoS ONE. 2012;7:e44765 pubmed publisher
Lin H, Yeh C. Genipin-crosslinked chitosan scaffolds and its efficacy in releasing anti-inflammatory medicine. Biomed Mater Eng. 2012;22:321-32 pubmed publisher
Hamama S, Gilbert Sirieix M, Vozenin M, Delanian S. Radiation-induced enteropathy: molecular basis of pentoxifylline-vitamin E anti-fibrotic effect involved TGF-?1 cascade inhibition. Radiother Oncol. 2012;105:305-12 pubmed publisher
Cakmak S, Cakmak A, Gonul M, Kilic A, Gul U. Pentoxifylline use in dermatology. Inflamm Allergy Drug Targets. 2012;11:422-32 pubmed
Shan D, Wu H, Yuan Q, Li J, Zhou R, Liu G. Pentoxifylline for diabetic kidney disease. Cochrane Database Syst Rev. 2012;:CD006800 pubmed publisher
LU D, Song H, Li Y, Clarke J, Shi G. Pentoxifylline for endometriosis. Cochrane Database Syst Rev. 2012;1:CD007677 pubmed publisher
Salhiyyah K, Senanayake E, Abdel Hadi M, Booth A, Michaels J. Pentoxifylline for intermittent claudication. Cochrane Database Syst Rev. 2012;1:CD005262 pubmed publisher
Squires H, Simpson E, Meng Y, Harnan S, Stevens J, Wong R, et al. A systematic review and economic evaluation of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease. Health Technol Assess. 2011;15:1-210 pubmed publisher
Haque K, Pammi M. Pentoxifylline for treatment of sepsis and necrotizing enterocolitis in neonates. Cochrane Database Syst Rev. 2011;:CD004205 pubmed publisher
Zheng W, Ouyang H, Zheng X, Liu S, Mata M, Fink D, et al. Glial TNF? in the spinal cord regulates neuropathic pain induced by HIV gp120 application in rats. Mol Pain. 2011;7:40 pubmed publisher
Badri S, Dashti Khavidaki S, Lessan Pezeshki M, Abdollahi M. A review of the potential benefits of pentoxifylline in diabetic and non-diabetic proteinuria. J Pharm Pharm Sci. 2011;14:128-37 pubmed
Li W, Zheng L, Sheng C, Cheng X, Qing L, Qu S. Systematic review on the treatment of pentoxifylline in patients with non-alcoholic fatty liver disease. Lipids Health Dis. 2011;10:49 pubmed publisher
Harris E, Schulzke S, Patole S. Pentoxifylline in preterm neonates: a systematic review. Paediatr Drugs. 2010;12:301-11 pubmed publisher
Gil M, Hernandez M, Roca J, Almiñana C, Lucas X, Cuello C, et al. Pentoxifylline added to freezing or post-thaw extenders does not improve the survival or in vitro fertilising capacity of boar spermatozoa. Reproduction. 2010;139:557-64 pubmed publisher
Appenzeller S, Hazel E. Pentoxifylline for the treatment of anterior uveitis in Behcet's disease: possible alternative for TNF blockers. Rheumatol Int. 2011;31:1511-3 pubmed publisher
Groesdonk H, Heringlake M, Heinze H. [Anti-inflammatory effects of pentoxifylline: importance in cardiac surgery]. Anaesthesist. 2009;58:1136-43 pubmed publisher
Whitfield K, Rambaldi A, Wetterslev J, Gluud C. Pentoxifylline for alcoholic hepatitis. Cochrane Database Syst Rev. 2009;:CD007339 pubmed publisher
Lv D, Song H, Li Y, Clarke J, Shi G. Pentoxifylline versus medical therapies for subfertile women with endometriosis. Cochrane Database Syst Rev. 2009;:CD007677 pubmed publisher
Shaw S, Shah M, Williams S, Fildes J. Immunological mechanisms of pentoxifylline in chronic heart failure. Eur J Heart Fail. 2009;11:113-8 pubmed publisher
Zargari O. Pentoxifylline: a drug with wide spectrum applications in dermatology. Dermatol Online J. 2008;14:2 pubmed
Renke M, Rutkowski P, Tylicki L, Zietkiewicz M, Larczynski W, Rutkowski B. [Pentoxifylline old drug or new hope for nephrology?]. Przegl Lek. 2008;65:358-61 pubmed
Wei T, Sabsovich I, Guo T, Shi X, Zhao R, Li W, et al. Pentoxifylline attenuates nociceptive sensitization and cytokine expression in a tibia fracture rat model of complex regional pain syndrome. Eur J Pain. 2009;13:253-62 pubmed publisher
Reuter B, Wallace J. Phosphodiesterase inhibitors prevent NSAID enteropathy independently of effects on TNF-alpha release. Am J Physiol. 1999;277:G847-54 pubmed publisher
Poulakis N, Androutsos G, Kazi D, Bastas A, Provata A, Bitsakou C, et al. The differential effect of pentoxifylline on cytokine production by alveolar macrophages and its clinical implications. Respir Med. 1999;93:52-7 pubmed
product information
Catalog Number :
P1784
Product Name :
Pentoxifylline
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA