product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-Podocin antibody produced in rabbit
catalog :
P0372
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 54
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; loading ...; fig s4d
Schell C, Sabass B, Helmstaedter M, Geist F, Abed A, Yasuda Yamahara M, et al. ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier. Dev Cell. 2018;47:741-757.e8 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 3b
Hou X, Dong H, Sun L, Yang M, Cheng H, Chen Y. Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome. Chin Med J (Engl). 2018;131:2713-2725 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2b
Qing X, Chinenov Y, Redecha P, Madaio M, Roelofs J, FARBER G, et al. iRhom2 promotes lupus nephritis through TNF-? and EGFR signaling. J Clin Invest. 2018;128:1397-1412 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 4a
Hu M, Azeloglu E, Ron A, Tran Ba K, Calizo R, Tavassoly I, et al. A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction. Sci Rep. 2017;7:43934 pubmed publisher
  • western blot; mouse
Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, et al. A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. JCI Insight. 2016;1: pubmed publisher
  • immunocytochemistry; mouse; 1:50; tbl 1
Li M, Corbelli A, Watanabe S, Armelloni S, Ikehata M, Parazzi V, et al. Three-dimensional podocyte-endothelial cell co-cultures: Assembly, validation, and application to drug testing and intercellular signaling studies. Eur J Pharm Sci. 2016;86:1-12 pubmed publisher
  • immunohistochemistry; rat; fig 4
Funk J, Ott V, Herrmann A, Rapp W, Raab S, Riboulet W, et al. Semiautomated quantitative image analysis of glomerular immunohistochemistry markers desmin, vimentin, podocin, synaptopodin and WT-1 in acute and chronic rat kidney disease models. Histochem Cell Biol. 2016;145:315-26 pubmed publisher
Sembach F, Fink L, Johansen T, Boland B, Secher T, Thrane S, et al. Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice. Physiol Rep. 2019;7:e14333 pubmed publisher
Lu X, Liu B, Cao Y, Song C, Su H, Chen G, et al. High glucose reduces expression of podocin in cultured human podocytes by stimulating TRPC6. Am J Physiol Renal Physiol. 2019;317:F1605-F1611 pubmed publisher
Puelles V, van der Wolde J, Wanner N, Scheppach M, Cullen McEwen L, Bork T, et al. mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans. JCI Insight. 2019;4: pubmed publisher
Abdallah M, Martin M, El Tahchi M, Balme S, Faour W, Varga B, et al. Influence of Hydrolyzed Polyacrylamide Hydrogel Stiffness on Podocyte Morphology, Phenotype, and Mechanical Properties. ACS Appl Mater Interfaces. 2019;11:32623-32632 pubmed publisher
Wehbi B, Oblet C, Boyer F, Huard A, Druilhe A, Paraf F, et al. Mesangial Deposition Can Strongly Involve Innate-Like IgA Molecules Lacking Affinity Maturation. J Am Soc Nephrol. 2019;: pubmed publisher
Nilsson D, Heglind M, Arani Z, Enerback S. Foxc2 is essential for podocyte function. Physiol Rep. 2019;7:e14083 pubmed publisher
Brinkkoetter P, Bork T, Salou S, Liang W, Mizi A, Ozel C, et al. Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics. Cell Rep. 2019;27:1551-1566.e5 pubmed publisher
Lin C, Hsu Y, Huang Y, Shih Y, Wang C, Chiang W, et al. A KDM6A-KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction. EMBO Mol Med. 2019;11: pubmed publisher
Li L, Liu Y, Li S, Yang R, Zeng C, Rong W, et al. Signal regulatory protein α protects podocytes through promoting autophagic activity. JCI Insight. 2019;5: pubmed publisher
Dylewski J, Dobrinskikh E, Lewis L, Tonsawan P, Miyazaki M, Jat P, et al. Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo. PLoS ONE. 2019;14:e0209732 pubmed publisher
Sieber K, Batorsky A, Siebenthall K, Hudkins K, Vierstra J, Sullivan S, et al. Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci. J Am Soc Nephrol. 2019;: pubmed publisher
Goto T, Hara H, Sanbo M, Masaki H, Sato H, Yamaguchi T, et al. Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. Nat Commun. 2019;10:451 pubmed publisher
Wanner N, Vornweg J, Combes A, Wilson S, Plappert J, Rafflenbeul G, et al. DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation. J Am Soc Nephrol. 2019;30:63-78 pubmed publisher
Gonçalves G, Costa Pessoa J, Thieme K, Lins B, Oliveira Souza M. Intracellular albumin overload elicits endoplasmic reticulum stress and PKC-delta/p38 MAPK pathway activation to induce podocyte apoptosis. Sci Rep. 2018;8:18012 pubmed publisher
Hale L, Howden S, Phipson B, Lonsdale A, Er P, Ghobrial I, et al. 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening. Nat Commun. 2018;9:5167 pubmed publisher
Rauch C, Feifel E, Kern G, Murphy C, Meier F, Parson W, et al. Differentiation of human iPSCs into functional podocytes. PLoS ONE. 2018;13:e0203869 pubmed publisher
Cooper C, Dutta N, Martin C, Piscione T, Thorner P, Jones N. Characterization of a novel disease-associated mutation within NPHS1 and its effects on nephrin phosphorylation and signaling. PLoS ONE. 2018;13:e0203905 pubmed publisher
Chozinski T, Mao C, Halpern A, Pippin J, Shankland S, Alpers C, et al. Volumetric, Nanoscale Optical Imaging of Mouse and Human Kidney via Expansion Microscopy. Sci Rep. 2018;8:10396 pubmed publisher
Niedenberger B, Cook K, Baena V, Serra N, Velte E, Agno J, et al. Dynamic cytoplasmic projections connect mammalian spermatogonia in vivo. Development. 2018;145: pubmed publisher
Wen H, Kumar V, Lan X, Shoshtari S, Eng J, Zhou X, et al. APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress. Biosci Rep. 2018;38: pubmed publisher
Armelloni S, Ikehata M, Mattinzoli D, Li M, Alfieri C, Rastaldi M, et al. NeuroD Expression in Podocytes and Interrelationships with Nephrin at Both Nuclear and Cytoplasmic Sites. Cell Physiol Biochem. 2018;46:873-889 pubmed publisher
Asfahani R, Tahoun M, Miller Hodges E, Bellerby J, Virasami A, Sampson R, et al. Activation of podocyte Notch mediates early Wt1 glomerulopathy. Kidney Int. 2018;93:903-920 pubmed publisher
Unnersjö Jess D, Scott L, Sevilla S, Patrakka J, Blom H, Brismar H. Confocal super-resolution imaging of the glomerular filtration barrier enabled by tissue expansion. Kidney Int. 2018;93:1008-1013 pubmed publisher
Martin C, Petersen K, Aoudjit L, Tilak M, Eremina V, Hardy W, et al. ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies. J Am Soc Nephrol. 2018;29:92-103 pubmed publisher
Lu S, Liu S, Wietelmann A, Kojonazarov B, Atzberger A, Tang C, et al. Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4). PLoS ONE. 2017;12:e0183166 pubmed publisher
Furuta I, Zhai T, Umazume T, Ishikawa S, Nakagawa K, Kojima T, et al. Effects of childbirth on podocyturia in women with normotensive, uncomplicated pregnancies. Am J Physiol Renal Physiol. 2017;312:F1112-F1119 pubmed publisher
Sambi M, Chow T, Whiteley J, Li M, Chua S, Raileanu V, et al. Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors. Stem Cell Rev. 2017;13:513-531 pubmed publisher
Kuppe C, Van Roeyen C, Leuchtle K, Kabgani N, Vogt M, van Zandvoort M, et al. Investigations of Glucocorticoid Action in GN. J Am Soc Nephrol. 2017;28:1408-1420 pubmed publisher
Fan X, Yang H, Kumar S, Tumelty K, Pisarek Horowitz A, Rasouly H, et al. SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. JCI Insight. 2016;1:e86934 pubmed publisher
Kindt F, Hammer E, Kemnitz S, Blumenthal A, Klemm P, Schlüter R, et al. A novel assay to assess the effect of pharmaceutical compounds on the differentiation of podocytes. Br J Pharmacol. 2017;174:163-176 pubmed publisher
Koehler S, Brähler S, Kuczkowski A, Binz J, Hackl M, Hagmann H, et al. Single and Transient Ca2+ Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion. Sci Rep. 2016;6:35400 pubmed publisher
Herrera M, Söderberg M, Sabirsh A, Valastro B, Mölne J, Santamaria B, et al. Inhibition of T-cell activation by the CTLA4-Fc Abatacept is sufficient to ameliorate proteinuric kidney disease. Am J Physiol Renal Physiol. 2017;312:F748-F759 pubmed publisher
Subramanian B, Sun H, Yan P, Charoonratana V, Higgs H, Wang F, et al. Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury. Kidney Int. 2016;90:363-372 pubmed publisher
Tan X, Chen Y, Liang X, Yu C, Lai Y, Zhang L, et al. Lipopolysaccharide-induced podocyte injury is mediated by suppression of autophagy. Mol Med Rep. 2016;14:811-8 pubmed publisher
Jarad G, Knutsen R, Mecham R, Miner J. Albumin contributes to kidney disease progression in Alport syndrome. Am J Physiol Renal Physiol. 2016;311:F120-30 pubmed publisher
Koehler S, Tellkamp F, Niessen C, Bloch W, Kerjaschki D, Schermer B, et al. Par3A is dispensable for the function of the glomerular filtration barrier of the kidney. Am J Physiol Renal Physiol. 2016;311:F112-9 pubmed publisher
Pullman J, Nylk J, Campbell E, Gunn Moore F, Prystowsky M, Dholakia K. Visualization of podocyte substructure with structured illumination microscopy (SIM): a new approach to nephrotic disease. Biomed Opt Express. 2016;7:302-11 pubmed publisher
New L, Martin C, Scott R, Platt M, Keyvani Chahi A, Stringer C, et al. Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture. J Am Soc Nephrol. 2016;27:2422-35 pubmed publisher
Enatsu N, Miyake H, Chiba K, Fujisawa M. Candesartan Mediated Amelioration of Cisplatin-Induced Testicular Damage Is Associated with Alterations in Expression Patterns of Nephrin and Podocin. Biomed Res Int. 2015;2015:273784 pubmed publisher
Sasaki H, Marusugi K, Kimura J, Kitamura H, Nagasaki K, Torigoe D, et al. Genetic background-dependent diversity in renal failure caused by the tensin2 gene deficiency in the mouse. Biomed Res. 2015;36:323-30 pubmed publisher
Unnersjö Jess D, Scott L, Blom H, Brismar H. Super-resolution stimulated emission depletion imaging of slit diaphragm proteins in optically cleared kidney tissue. Kidney Int. 2016;89:243-7 pubmed publisher
Chang W, Fornoni A, Tietjen G, Mendez J, Niklason L, Saltzman W, et al. Tissue-Engineered Microvasculature to Reperfuse Isolated Renal Glomeruli. Tissue Eng Part A. 2015;21:2673-9 pubmed publisher
Chung J, Huber T, Gödel M, Jarad G, Hartleben B, Kwoh C, et al. Albumin-associated free fatty acids induce macropinocytosis in podocytes. J Clin Invest. 2015;125:2307-16 pubmed publisher
Ising C, Koehler S, Brähler S, Merkwirth C, Höhne M, Baris O, et al. Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure. EMBO Mol Med. 2015;7:275-87 pubmed publisher
Kalwa H, Storch U, Demleitner J, Fiedler S, Mayer T, Kannler M, et al. Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes. J Cell Physiol. 2015;230:1389-99 pubmed publisher
Aggarwal P, Veron D, Thomas D, Siegel D, Moeckel G, Kashgarian M, et al. Semaphorin3a promotes advanced diabetic nephropathy. Diabetes. 2015;64:1743-59 pubmed publisher
Ding Z, Xu L, Wang S, Kou J, Xu Y, Chen C, et al. Ameliorating Adriamycin-Induced Chronic Kidney Disease in Rats by Orally Administrated Cardiotoxin from Naja naja atra Venom. Evid Based Complement Alternat Med. 2014;2014:621756 pubmed publisher
product information
Product No. :
P0372
Product Name :
Anti-Podocin antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for indirect immunofluorescence: 10-20 μg/mL using acetone-fixed human or rat kidney frozen sections; western blot (chemiluminescent): 0.5-1 μg/mL using whole extract of rat glomeruli
Species Reactivity :
rat, mouse, human
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA