This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Oncostatin M human
catalog :
O9635
citations: 41
Reference
Grimm F, Iwata Y, Sirenko O, Bittner M, Rusyn I. High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes. Assay Drug Dev Technol. 2015;13:529-46 pubmed publisher
Pothoven K, Norton J, Hulse K, Suh L, Carter R, Rocci E, et al. Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease. J Allergy Clin Immunol. 2015;136:737-746.e4 pubmed publisher
Lapeire L, Hendrix A, Lambein K, Van Bockstal M, Braems G, Van Den Broecke R, et al. Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/STAT3 signaling. Cancer Res. 2014;74:6806-19 pubmed publisher
Lauber S, Wong S, Cutz J, Tanaka M, Barra N, Lhotak S, et al. Novel function of Oncostatin M as a potent tumour-promoting agent in lung. Int J Cancer. 2015;136:831-43 pubmed publisher
Aranda A, Bezunartea J, Casales E, Rodriguez Madoz J, Larrea E, Prieto J, et al. A quick and efficient method to generate mammalian stable cell lines based on a novel inducible alphavirus DNA/RNA layered system. Cell Mol Life Sci. 2014;71:4637-51 pubmed publisher
Proctor C, MacDonald C, Milner J, Rowan A, Cawston T. A computer simulation approach to assessing therapeutic intervention points for the prevention of cytokine-induced cartilage breakdown. Arthritis Rheumatol. 2014;66:979-89 pubmed publisher
Karakawa M, Komine M, Hanakawa Y, Tsuda H, Sayama K, Tamaki K, et al. CCL27 is downregulated by interferon gamma via epidermal growth factor receptor in normal human epidermal keratinocytes. J Cell Physiol. 2014;229:1935-45 pubmed publisher
Szibor M, Pöling J, Warnecke H, Kubin T, Braun T. Remodeling and dedifferentiation of adult cardiomyocytes during disease and regeneration. Cell Mol Life Sci. 2014;71:1907-16 pubmed publisher
Stobbe Maicherski N, Wolff S, Wolff C, Abel J, Sydlik U, Frauenstein K, et al. The interleukin-6-type cytokine oncostatin M induces aryl hydrocarbon receptor expression in a STAT3-dependent manner in human HepG2 hepatoma cells. FEBS J. 2013;280:6681-90 pubmed publisher
Wang Y, van Boxel Dezaire A, Cheon H, Yang J, Stark G. STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor. Proc Natl Acad Sci U S A. 2013;110:16975-80 pubmed publisher
Migita K, Izumi Y, Torigoshi T, Satomura K, Izumi M, Nishino Y, et al. Inhibition of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signalling pathway in rheumatoid synovial fibroblasts using small molecule compounds. Clin Exp Immunol. 2013;174:356-63 pubmed publisher
Rinaldi A, Mensah A, Kwee I, Forconi F, Orlandi E, Lucioni M, et al. Promoter methylation patterns in Richter syndrome affect stem-cell maintenance and cell cycle regulation and differ from de novo diffuse large B-cell lymphoma. Br J Haematol. 2013;163:194-204 pubmed publisher
Sörensen Zender I, Rong S, Susnik N, Lange J, Gueler F, Degen J, et al. Role of fibrinogen in acute ischemic kidney injury. Am J Physiol Renal Physiol. 2013;305:F777-85 pubmed publisher
Guo L, Chen C, Shi M, Wang F, Chen X, Diao D, et al. Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition. Oncogene. 2013;32:5272-82 pubmed publisher
Giot J, Paris I, Levillain P, Huguier V, Charreau S, Delwail A, et al. Involvement of IL-1 and oncostatin M in acanthosis associated with hypertensive leg ulcer. Am J Pathol. 2013;182:806-18 pubmed publisher
Liang H, Block T, Wang M, Nefsky B, Long R, Hafner J, et al. Interleukin-6 and oncostatin M are elevated in liver disease in conjunction with candidate hepatocellular carcinoma biomarker GP73. Cancer Biomark. 2012;11:161-71 pubmed publisher
Wang M, Pan C, Chiou S, Chen W, Chang H, Lee O, et al. Oncostatin m modulates the mesenchymal-epithelial transition of lung adenocarcinoma cells by a mesenchymal stem cell-mediated paracrine effect. Cancer Res. 2012;72:6051-64 pubmed publisher
Canady J, Arndt S, Karrer S, Bosserhoff A. Increased KGF expression promotes fibroblast activation in a double paracrine manner resulting in cutaneous fibrosis. J Invest Dermatol. 2013;133:647-657 pubmed publisher
Albasanz Puig A, Murray J, Namekata M, Wijelath E. Opposing roles of STAT-1 and STAT-3 in regulating vascular endothelial growth factor expression in vascular smooth muscle cells. Biochem Biophys Res Commun. 2012;428:179-84 pubmed publisher
Tu H, Lin T, Chiu Y, Tang C, Yang R, Fu W. Enhancement of placenta growth factor expression by oncostatin M in human rheumatoid arthritis synovial fibroblasts. J Cell Physiol. 2013;228:983-90 pubmed publisher
Sone M, Nishikawa Y, Nagahama Y, Kumagai E, Doi Y, Omori Y, et al. Recovery of mature hepatocytic phenotype following bile ductular transdifferentiation of rat hepatocytes in vitro. Am J Pathol. 2012;181:2094-104 pubmed publisher
David E, Tirode F, Baud huin M, Guihard P, Laud K, Delattre O, et al. Oncostatin M is a growth factor for Ewing sarcoma. Am J Pathol. 2012;181:1782-95 pubmed publisher
Ko H, Kang H, Kim H, Choi S, Park I, Shin J. The effects of oncostatin M on trophoblast cells: influence on matrix metalloproteinases-2 and -9, and invasion activity. Placenta. 2012;33:908-13 pubmed publisher
Ganesh K, Das A, Dickerson R, Khanna S, Parinandi N, Gordillo G, et al. Prostaglandin E? induces oncostatin M expression in human chronic wound macrophages through Axl receptor tyrosine kinase pathway. J Immunol. 2012;189:2563-73 pubmed publisher
Chollangi S, Mather T, Rodgers K, Ash J. A unique loop structure in oncostatin M determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor. J Biol Chem. 2012;287:32848-59 pubmed
Sarközi R, Flucher K, Haller V, Pirklbauer M, Mayer G, Schramek H. Oncostatin M inhibits TGF-?1-induced CTGF expression via STAT3 in human proximal tubular cells. Biochem Biophys Res Commun. 2012;424:801-6 pubmed publisher
Nicolaidou V, Wong M, Redpath A, Ersek A, Baban D, Williams L, et al. Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation. PLoS ONE. 2012;7:e39871 pubmed publisher
Kanda N, Hau C, Tada Y, Sato S, Watanabe S. Decreased serum LL-37 and vitamin D3 levels in atopic dermatitis: relationship between IL-31 and oncostatin M. Allergy. 2012;67:804-12 pubmed publisher
Ishkitiev N, Yaegaki K, Imai T, Tanaka T, Nakahara T, Ishikawa H, et al. High-purity hepatic lineage differentiated from dental pulp stem cells in serum-free medium. J Endod. 2012;38:475-80 pubmed publisher
Pechkovsky D, Prele C, Wong J, Hogaboam C, McAnulty R, Laurent G, et al. STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF. Am J Pathol. 2012;180:1398-412 pubmed publisher
Gilbert S, Blain E, al Sabah A, Zhang Y, Duance V, Mason D. Protein kinase R plays a pivotal role in oncostatin M and interleukin-1 signalling in bovine articular cartilage chondrocytes. Eur Cell Mater. 2012;23:41-57 pubmed
West N, Murphy L, Watson P. Oncostatin M suppresses oestrogen receptor-? expression and is associated with poor outcome in human breast cancer. Endocr Relat Cancer. 2012;19:181-95 pubmed publisher
Guihard P, Danger Y, Brounais B, David E, Brion R, Delecrin J, et al. Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling. Stem Cells. 2012;30:762-72 pubmed publisher
Pöling J, Gajawada P, Lörchner H, Polyakova V, Szibor M, Böttger T, et al. The Janus face of OSM-mediated cardiomyocyte dedifferentiation during cardiac repair and disease. Cell Cycle. 2012;11:439-45 pubmed publisher
Becerik S, Oztürk V, Atmaca H, Atilla G, Emingil G. Gingival crevicular fluid and plasma acute-phase cytokine levels in different periodontal diseases. J Periodontol. 2012;83:1304-13 pubmed
Langeslag M, Constantin C, Andratsch M, Quarta S, Mair N, Kress M. Oncostatin M induces heat hypersensitivity by gp130-dependent sensitization of TRPV1 in sensory neurons. Mol Pain. 2011;7:102 pubmed publisher
Kanda N, Watanabe S. Increased serum human β-defensin-2 levels in atopic dermatitis: relationship to IL-22 and oncostatin M. Immunobiology. 2012;217:436-45 pubmed publisher
Chen Y, Tseng C, Wang H, Kuo H, Yang V, Lee O. Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol. Hepatology. 2012;55:1193-203 pubmed publisher
Kubin T, Pöling J, Kostin S, Gajawada P, Hein S, Rees W, et al. Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling. Cell Stem Cell. 2011;9:420-32 pubmed publisher
Inada M, Follenzi A, Cheng K, Surana M, Joseph B, Benten D, et al. Phenotype reversion in fetal human liver epithelial cells identifies the role of an intermediate meso-endodermal stage before hepatic maturation. J Cell Sci. 2008;121:1002-13 pubmed publisher
Kitamura T, Tange T, Terasawa T, Chiba S, Kuwaki T, Miyagawa K, et al. Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J Cell Physiol. 1989;140:323-34 pubmed
product information
Catalog Number :
O9635
Product Name :
Oncostatin M human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
BioReagent, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA